MX2009006325A - 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents. - Google Patents

2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents.

Info

Publication number
MX2009006325A
MX2009006325A MX2009006325A MX2009006325A MX2009006325A MX 2009006325 A MX2009006325 A MX 2009006325A MX 2009006325 A MX2009006325 A MX 2009006325A MX 2009006325 A MX2009006325 A MX 2009006325A MX 2009006325 A MX2009006325 A MX 2009006325A
Authority
MX
Mexico
Prior art keywords
quinoxalinone
quinolinone
derivatives
antibacterial agents
compounds
Prior art date
Application number
MX2009006325A
Other languages
Spanish (es)
Inventor
Janelle Comita-Prevoir
Mark Cronin
Bolin Geng
Andrew Aydon Godfrey
Folkert Reck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39046831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009006325(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2009006325A publication Critical patent/MX2009006325A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The present invention relates to compounds of Formula (I) : and pharmaceutically acceptable salts thereof, to their use in the treatment of bacterial infections, and to their methods of preparation.
MX2009006325A 2006-12-15 2007-12-13 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents. MX2009006325A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87018106P 2006-12-15 2006-12-15
US96916307P 2007-08-30 2007-08-30
PCT/GB2007/004766 WO2008071961A1 (en) 2006-12-15 2007-12-13 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents

Publications (1)

Publication Number Publication Date
MX2009006325A true MX2009006325A (en) 2009-07-24

Family

ID=39046831

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006325A MX2009006325A (en) 2006-12-15 2007-12-13 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents.

Country Status (17)

Country Link
EP (1) EP2121702A1 (en)
JP (1) JP2010513255A (en)
KR (1) KR20090090385A (en)
AR (1) AR064369A1 (en)
AU (1) AU2007331247B2 (en)
BR (1) BRPI0720236A2 (en)
CA (1) CA2671485A1 (en)
CL (1) CL2007003641A1 (en)
CO (1) CO6190619A2 (en)
EC (1) ECSP099506A (en)
MX (1) MX2009006325A (en)
NO (1) NO20092655L (en)
PE (1) PE20081511A1 (en)
RU (1) RU2009126731A (en)
TW (1) TW200831517A (en)
UY (1) UY30788A1 (en)
WO (1) WO2008071961A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (en) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. Novel nitrogenated heterocyclic compound and salt thereof
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
CN102164919B (en) 2008-10-10 2014-04-09 埃科特莱茵药品有限公司 Oxazolidinyl antibiotics
AR076222A1 (en) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
KR20140033309A (en) * 2010-10-04 2014-03-18 브리티쉬 콜롬비아 캔써 에이전시 브랜치 Detection of fusobacterium in a gastrointestinal sample to diagnose gastrointestinal cancer
BR112020003477A2 (en) 2017-08-21 2020-08-25 Acadia Pharmaceuticals, Inc. compounds and method for treating a disease
WO2019040104A2 (en) * 2017-08-21 2019-02-28 Acadia Pharmaceuticals Inc. Compounds, salts thereof and methods for treatment of diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19601265A1 (en) * 1996-01-16 1997-07-17 Bayer Ag 2-oxo and 2-thio-1,2-dihydroquinolinyl oxazolidinones
TW200409637A (en) 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
JP5314244B2 (en) * 2004-10-27 2013-10-16 富山化学工業株式会社 Novel nitrogen-containing heterocyclic compounds and salts thereof
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (en) * 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. Novel nitrogenated heterocyclic compound and salt thereof
KR101409261B1 (en) * 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 Novel heterocyclic compound or salt thereof and intermediate thereof
JP2009539807A (en) * 2006-06-09 2009-11-19 グラクソ グループ リミテッド Substituted 1-methyl-1H-quinolin-2-one and 1-methyl-1H-1,5-naphthyridin-2-one as antibacterial agents
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
JP5315239B2 (en) * 2006-07-20 2013-10-16 グラクソ グループ リミテッド N-ethylquinolone and derivatives and analogs of N-ethylazaquinolone
EP1992628A1 (en) * 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones

Also Published As

Publication number Publication date
BRPI0720236A2 (en) 2013-12-24
AU2007331247B2 (en) 2011-10-20
JP2010513255A (en) 2010-04-30
CO6190619A2 (en) 2010-08-19
WO2008071961A8 (en) 2009-10-22
KR20090090385A (en) 2009-08-25
UY30788A1 (en) 2008-07-31
TW200831517A (en) 2008-08-01
CL2007003641A1 (en) 2008-09-22
WO2008071961A1 (en) 2008-06-19
EP2121702A1 (en) 2009-11-25
PE20081511A1 (en) 2008-12-12
NO20092655L (en) 2009-09-02
ECSP099506A (en) 2009-08-28
RU2009126731A (en) 2011-01-20
AR064369A1 (en) 2009-04-01
CA2671485A1 (en) 2008-06-19
AU2007331247A1 (en) 2008-06-19

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Legal Events

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