LT2629776T - Junginiai, kompozicijos ir būdai, tinkami cholesterolio mobilizavimui - Google Patents

Junginiai, kompozicijos ir būdai, tinkami cholesterolio mobilizavimui

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Publication number
LT2629776T
LT2629776T LTEP11835025.5T LT11835025T LT2629776T LT 2629776 T LT2629776 T LT 2629776T LT 11835025 T LT11835025 T LT 11835025T LT 2629776 T LT2629776 T LT 2629776T
Authority
LT
Lithuania
Prior art keywords
compositions
compounds
methods useful
mobilisation
cholesterol
Prior art date
Application number
LTEP11835025.5T
Other languages
English (en)
Inventor
Daniela Carmen Oniciu
Jean-Louis Henri Dasseux
Ronald Barbaras
Valery Kochubey
Dmitry Kovalsky
Oleg Gennadievich Rodin
Otto Geoffroy
Anna Rzepiela
Original Assignee
Cerenis Therapeutics Holding Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerenis Therapeutics Holding Sa filed Critical Cerenis Therapeutics Holding Sa
Publication of LT2629776T publication Critical patent/LT2629776T/lt

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • C07D211/40—Oxygen atoms
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    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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