KR20200141555A - Artificial disc and method for manufacturing the same - Google Patents

Abstract

Disclosed are an artificial disc installed between vertebrae facing each other and a method for manufacturing the same. The disclosed artificial disk includes: a first plate which is installed by being in contact with any one of the vertebrae, includes at least one first fixing protrusion formed on one surface that is in contact with one of the vertebrae so as to prevent separation, and has a first receiving groove formed on the other surface; a second plate which includes at least one second fixing protrusion formed on one surface that is in contact with the other of the vertebrae so as to prevent separation, and has a second receiving groove formed on the other surface; a core motion member which is located between the first receiving groove and the second receiving groove and moves so that the second plate can be relatively subjected to a plane motion and a rotational motion with respect to the first plate; and a buffer member which is installed between a part of the core motion member and the first plate, has a third receiving groove formed therein, and reduces impact and noise when the first plate is relatively subjected to a plane motion with respect to the core movement member.

Description

Artificial disk and its manufacturing method {ARTIFICIAL DISC AND METHOD FOR MANUFACTURING THE SAME}

The present invention relates to an artificial disk, and more particularly, to an artificial disk that can be used for a long period of time by maintaining the shape unchanged even with the force received from the movement of the spine after implantation and reducing frictional shock and noise, and to a manufacturing method thereof.

The spine is a long bone structure that supports the body at the back of the body, with a total of 26 vertebrae including 7 cervical vertebrae, 12 thoracic vertebrae, 5 lumbar vertebrae, 1 sacrum and 1 tailbone. Consists of. Apart from the sacrum and tailbone, there is a disc (intervertebral disc), a strong connective tissue that connects the vertebrae between the vertebrae. At this time, the disk can function as a cushion between the vertebrae, that is, a shock absorbing function during weight loading.

On the other hand, the disc may cause pain by aging, physical overload, strong external shock, incorrect posture, etc., such as degenerative changes, where the nucleus in the disc penetrates the outer layer of fibroblasts and presses the surrounding nerves. If the function of such a disk is lost, it can be replaced with an artificial disk that performs the same function. This artificial disc can restore and maintain the original height of the disc, which has been lowered due to the removal of the nucleus of the existing disc, as well as restore the natural moving function of the disc. Therefore, various kinds of artificial spinal discs are currently being developed and used. However, the conventional artificial disc for spine has a problem in that it is separated between the vertebrae after implantation or local kyphosis and non-fusion occur. In addition, there is a problem in that patients complain of discomfort during physical spine movement in daily life, and furthermore, noticeable noise is generated due to friction inside the artificial disc.

Korean Patent Publication No. 10-1457763 (October 28, 2014) Republic of Korea Patent Publication No. 10-2013-0055226 (2013.05.28.)

The present invention has been invented in view of the above points, and an object thereof is to provide an artificial disk that can be used for a long time by reducing frictional impact and noise inside the artificial disk, and a manufacturing method thereof.

In order to achieve the above object, in the artificial disc installed between the vertebrae facing each other, at least one of the vertebrae is installed in contact with one of the vertebrae, and is formed on one surface of the vertebrae to prevent separation. A first plate having one first fixing protrusion and having a first receiving groove formed on the other surface thereof; It is installed in contact with the other of the vertebrae, and has at least one second fixing protrusion formed on one surface in contact with the other vertebrae of the vertebrae to prevent separation, and a second receiving groove is formed on the other surface. With two plates; A core movement member positioned between the first receiving groove and the second receiving groove and moving so that the second plate can relatively move in plane and rotate relative to the first plate; And a third receiving groove is formed between a portion of the core movement member and the first plate, wherein the first plate relative to the core movement member reduces impact and noise during a plane movement. It may include a buffer member.

The first receiving groove has a semicircular shape and a pair of semicircular portions formed to be spaced apart from each other at predetermined intervals; It may include an extension formed extending in the spaced portion between the pair of semicircular portions.

A planar motion part which is installed in contact with the buffer member and makes a relatively planar motion with respect to the first plate together with the buffer member; A rotation movement part connected to the plane movement part and installed in the second receiving groove, and formed in a curved surface so that the second plate rotates relative to the core movement part; And a neck portion interposed between the planar motion part and the rotational motion part and configured to lock the side surface of the first receiving groove while supporting the plane motion part for the load of the rotational motion part.

The core motion member may further include a lead-in portion inserted into at least a portion of the rotational motion portion.

The lead-in portion may include at least one selected from a hole formed in the center of the rotational movement portion, a plurality of dimples lead-in throughout the rotational movement portion, and a groove formed linearly on the rotational movement portion.

It is accommodated in the interior of the inlet, it may further include a spine strengthening agent to strengthen the lubrication function and spine.

The core movement part may be made of ceramic, and the buffer member may be made of a synthetic polymer material.

The second plate has a predetermined thickness, an upper portion forming a curved surface, and a lower portion forming a flat surface, and the height of one surface of the front surface may be greater than the height of the surface of the rear surface.

The first and second fixing protrusions are formed in a plurality, and are located on one surface of each of the first plate and the second plate in contact with the first and second cervical vertebrae, and the gap between the first and second fixing protrusions It can be arranged narrower from the front to the rear.

Each of the first plate and the second plate includes a body made of a metallic material of a cobalt-chromium-molybdenum alloy; And a coating layer coated with at least one of titanium and hydroxyapatite on one surface of the body in contact with the first and second cervical vertebrae.

When the second plate moves with respect to the first plate, a range of an inner maximum angle therebetween may be 20 to 25°.

In addition, in the artificial disc installed between the vertebrae facing each other, at least one first fixing protrusion that is installed in contact with one of the vertebrae and formed on one surface in contact with any one of the vertebrae to prevent separation And a first plate having a first receiving groove formed on the other surface thereof; A second plate having at least one second fixing protrusion formed on one surface of the vertebrae in contact with the other vertebrae to prevent separation, and having a second receiving groove formed on the other surface; A core motion member positioned between the first receiving groove and the second receiving groove, reducing impact and noise while moving relatively flat with respect to the first plate, and rotating relative to the second plate. And, the core movement member is installed in contact with the second receiving groove, and is formed in a curved surface to rotate relative to the second plate; A plan that is located on the lower surface of the core movement member and is installed in contact with the first receiving groove and moves relatively flat with respect to the first plate to prevent separation from within the first receiving groove and reduce impact and noise chapter; And a neck part interposed between the rotational movement part and the flange part, which locks in the first receiving groove so that the flange part can be fitted and installed, and reduces impact and noise during the plane movement of the core movement member.

The core motion member may further include a lead-in portion inserted into at least a portion of the rotational motion portion.

The first receiving groove has a semicircular shape and a pair of semicircular portions formed to be spaced apart from each other at predetermined intervals; It may include an extension formed extending in the spaced portion between the pair of semicircular portions.

In addition, in the method of manufacturing an artificial disk comprising a first plate, a second plate, a core movement member installed between the vertebrae facing each other, and a buffer member installed between the first plate and the core movement member, To manufacture a first plate in which a plurality of first fixing protrusions are formed on one surface in contact with any one spine, and a pair of semicircles are spaced apart by a predetermined distance on the other surface, and a first receiving groove is formed in a shape with an extension part extending therebetween. step; Manufacturing a second plate having a plurality of second fixing protrusions formed on one surface of the vertebrae in contact with the other vertebrae and having a second receiving groove formed on the other surface; It is formed in a curved surface on the upper side and the rotation movement part for relatively rotating movement of the second plate, and a plane movement part formed in a plane on the lower side for relatively plane movement of the first plate, and interposed between the rotation movement part and the plane movement part Manufacturing a core motion member including a neck portion formed on a side surface; It is installed between the first plate and the core movement member, and a third receiving groove is formed therein, and the first plate is made of an elastic material that relieves impact and noise when the first plate is relatively flat with respect to the core movement member. Manufacturing a buffer member; And inserting and installing the core movement member and the buffer member integrated between the first plate and the second plate to final assembly.

The step of manufacturing the core motion part may further include a lead-in part inserted into at least a part of the rotational motion part.

The artificial disk according to the present invention has a range of the maximum internal angle between the first plate and the second plate when the second plate flows, thereby improving the indications for surgery and neck motility of patients after transplantation, so that there is no restriction on the activities of daily life. .

In addition, the artificial disk according to the present invention includes a buffer member to reduce frictional impact and noise between the core center and the first plate, and can be used for a long time.

In addition, in the method for manufacturing an artificial disk according to the present invention, it is easy to insert and fasten the core center member to the first plate, but it is possible to prevent separation after implantation.

1 is a cross-sectional view showing a state in which an artificial disk according to an embodiment of the present invention is inserted between adjacent cervical vertebrae in the direction B and then installed.
Figure 2 is an exploded view showing an artificial disk according to an embodiment of the present invention.
3 is an exploded cross-sectional view taken along line III-III of FIG. 2.
Figure 4a is an assembly cross-sectional view showing a first embodiment of an artificial disk according to an embodiment of the present invention.
Figure 4b is an assembly cross-sectional view showing a second embodiment of an artificial disk according to an embodiment of the present invention.
Figure 4c is an assembly cross-sectional view showing a third embodiment of the artificial disk according to an embodiment of the present invention.
Figure 5a is a front view showing a second plate of the artificial disk according to an embodiment of the present invention.
5B is a plan view showing a second plate of an artificial disk according to an embodiment of the present invention.
6 is a cross-sectional view showing a core center member according to a first modified example of an artificial disk according to an embodiment of the present invention.
7A is a cross-sectional view showing a core center member according to a second modified example of an artificial disk according to an embodiment of the present invention.
Figure 7b is a plan view showing the rotation movement of Figure 7a.
8A is a cross-sectional view showing a core center member according to a third modified example of an artificial disk according to an embodiment of the present invention.
Figure 8b is a plan view showing the rotation movement of Figure 8a.
Figure 9 is an enlarged view of the main part, the combined cross-sectional view of Figure 4c.
10A is a cross-sectional view showing an operating state in the C and D directions of the artificial disk according to an embodiment of the present invention.
Figure 10b is a cross-sectional view showing an operating state of the A-direction of the artificial disk according to an embodiment of the present invention.
Figure 10c is a cross-sectional view showing an operating state in the B direction of the artificial disk according to an embodiment of the present invention.
11 is an exploded view showing an artificial disk according to another embodiment of the present invention.
12 is an exploded cross-sectional view taken along line XII-XII of FIG. 11;

Hereinafter, an artificial disk according to an embodiment of the present invention and a method of manufacturing the same will be described in detail with reference to the accompanying drawings. Here, the accompanying drawings are partially exaggerated or simplified for convenience and clarity of explanation and understanding of the configuration and operation of the technology, and each component does not exactly match the actual size.

First, a direction will be defined for the purpose of describing the present invention. With the artificial disc inserted into the patient's spine, the direction facing the patient's front (forward) is referred to as'A' (forward) for convenience of explanation, and the opposite direction, that is, the direction facing the patient's back (rear) Is referred to as'B' (rear) for convenience of explanation. And, for convenience of explanation, the term'left and right direction' refers to a direction perpendicular to the line connecting A and B on a two-dimensional plane and located on the left and right sides, for convenience of explanation,'C' (left) and'D' (right). It is called.

1 is a cross-sectional view showing a state in which an artificial disk according to an embodiment of the present invention is installed after being inserted in the direction B into A between one of the vertebrae and the other of the vertebrae. Here, the spine is a long bone structure that supports the body at the back of the body, and in detail, it refers to a vertebrae consisting of cervical, thoracic and lumbar vertebrae. Therefore, the spine referred to in the drawings may mean at least one of these.

One of the vertebrae (1) refers to the lower vertebrae (lower vertebrae), and the other of the vertebrae (3) refers to the upper vertebrae (vertebral body) corresponding to any one of the vertebrae (1). it means. The artificial disk 100 according to the embodiment of the present invention is installed between one of the spines 1 and the other spine 3, and is installed in the direction A (forward), that is, the patient's It can be installed in a direction from the front (front) to the B (rear), that is, to the rear (rear) of the patient. In addition, one of the vertebrae (1) and the other (3) are the smallest among the vertebrae and are formed in a'C' shape as a whole, so they are easier to move than other vertebrae, such as rotation, shaking, noding, etc. Exercise. For example, in the case of'head nod', one of the spines and the other (1)(3) of the spine can move in the A and B directions, and in the'shaking and rotation of the head', A, B, C And one of the vertebrae and the other vertebrae 1 and 3 may move in at least one of the D directions.

2 is an exploded view showing an artificial disk according to an embodiment of the present invention, and FIG. 3 is an exploded cross-sectional view taken along line III-III of FIG. 2.

2 and 3, the artificial disk 100 according to an embodiment of the present invention includes a first plate 110 installed in contact with one of the vertebrae 1 and the other vertebrae of the vertebrae ( It may include a second plate 170 installed in contact with 3), a core movement member 150 and a buffer member 157 installed between the first and second plates 110 and 170.

The first plate 110 includes at least one first fixing protrusion 115 that is formed on one side of the spine and is formed on one side to prevent separation, and the other side thereof is a first receiving groove 111 ) Can be formed. In detail, the first fixing protrusion 115 is formed in a transverse direction above the first plate 110 to prevent the artificial disc 100 from being separated from one of the vertebrae and the other vertebrae (1) (3). can do.

Here, the first receiving groove 111 may be formed such that a pair of semicircles are spaced apart at predetermined intervals and have a concave curved surface. For example, the first receiving groove 111 may have a groove shape such as a rumen shape that is concave toward the inner center. The function of the concave curved surface of the first receiving groove 111 can buffer the impact and pressure that the first plate 110 receives from the second plate 170 and the core motion member 150 during spinal segmental motion.

In addition, the first receiving groove may include a semicircular portion 113 and an extension portion 117. Here, the semicircular portions 113 may have a semicircular shape and may have a pair formed to be spaced apart from each other at predetermined intervals. The extension portion 117 may be formed to extend at a spaced portion between the pair of semicircular portions 113.

Here, since the extension part 117 has an elliptical shape and the left and right sides on a two-dimensional plane are wider than the lower surface of the core movement member 150, it can be easily fastened even if it is fastened in any direction of the lower surface of the core movement member 150. On the other hand, since the extension portion 117 of the first receiving groove 111 and the upper and lower lengths of the lower surface of the core motion member 150 are identical, the core motion member 150 may be tilted and fastened. Therefore, the structure in which the first receiving groove has the extension part 117 can prevent the core movement member 150 from being separated and separated even after fastening with the first plate 110. In addition, the first plate 110 has a first tool groove 119 having a depth coinciding with the tool on both sides in order to fix a tool for installation on one of the spines and the other spine (1) (3). It may further include.

The second plate 170 has at least one second fixing protrusion 175 that is formed on one surface of the vertebrae and is formed on one surface of the vertebrae to prevent separation, and a second receiving groove 171 on the other surface thereof. ) Can be formed. Here, the second receiving groove 171 may be formed in a hemispherical shape concave therein. In addition, the second plate 170 has a second tool groove 179 having a depth coinciding with the tool on both sides to fix a tool for installation on one of the spines and the other spine (1) (3). It may further include.

The core movement member 150 is located between the first receiving groove 111 and the second receiving groove 171, and the second plate 170 can relatively move in plane and rotation with respect to the first plate 110. To be able to exercise. The core movement member 150 may include a plane movement part 153, a rotation movement part 155, and a neck part 153 in detail referring to FIG. 3. The plane movement part 153 is installed in contact with the buffer member 157 and can move in a relatively plane with respect to the first plate 110 together with the buffer member 157. The rotational movement part 155 is connected to the plane movement part 153 and is installed in the second receiving groove 171, and is formed in a curved surface so that the second plate 170 rotates relative to the core movement member 150. I can. The neck part 153 is interposed between the plane movement part 153 and the rotation movement part 155, and the load of the rotation movement part 155 is supported by the plane movement part 153 and is locked to the side of the first receiving groove 111 You can do it. That is, the neck portion 153 may play a role of balancing and supporting the load as the area of the rotational motion portion 155 has a load and has a larger area than the planar motion portion 153.

The buffer member 157 may be installed between the core movement member 150 and the first plate 110, and a third receiving groove 151 in which the core movement member 150 is in contact and installed may be formed therein. In addition, the first plate 110 relative to the core movement member 150 may play a buffering role to reduce impact and noise during relatively flat movement.

The core motion member 150 may be made of ceramic, and the buffer member 157 may be made of a synthetic polymer material. That is, the core exercise member 150 is made of a ceramic material having stronger mechanical strength, and the buffer member 157 is durable and prevents impact and noise due to movement between the core exercise member 150 and the first plate 110. Synthetic polymer materials that are more suitable for buffering can be used. Therefore, the core motion member 150 and the buffer member 157 are made of materials of mutually complementary properties to absorb shock even after installation and reduce noise, thereby enabling long-term use.

The core motion member 150 may be made of ceramics. In particular, as a material applied to artificial teeth, artificial bones, and artificial organs, it can be made of ceramics with chemical stability and biocompatibility. For example, fine ceramics, ceramics mainly made of silicon nitride, alumina (Al ₂ O ₂ ), zirconia (Zirconia, ZrO ₂ ), hydroxyapatite (hydroxyapatite, Ca ₁₀ (PO ₄ ) ₆ (OH)) ₂ ), TCP (Tricalcium Phosphate), etc. may be included. These ceramics are excellent in biocompatibility and excellent in compressive strength and wear resistance. In addition, ceramic has excellent mechanical strength and excellent impact resistance, so even if it is separated between the first and second plates 110 and 170 and settles inside the human body, it is inactive inside the living body. Does not cause However, the core motion member 150 is not limited to a ceramic material, and synthetic polymer materials such as polyvinyl chloride (PVC), polypropylene (PP, Polypr-opylene), polyamide (Nylons, Polyamide) , Polymethylmethacrylate (PMMA), silicone, ultra-high-molecular polyethylene (UHMWPE), etc., biopolymer materials such as collagen (collagen-collagen), polysaccharides And the like and metal materials, for example, stainless steel, Co-Cr alloy, titanium (Ti), titanium alloy, and at least one of biocompatible materials such as shape memory alloy can be variously manufactured.

In addition, the buffer member 157 is made of a synthetic polymer material to reduce the occurrence of noise and reduce friction due to impact when the core movement member 15 moves relatively flat with the first plate 110. Can be. Synthetic polymers are, for example, polyvinyl chloride (PVC, Polyvinylchloride), polypropylene (PP, Polypr-opylene), polyamides (Nylons, Polyamide), polymethyl methacrylate (PMMA, Polymethylmethacryulate), silicone (Silicon) And ultra-high-molecular polyethylene (UHMWPE), and the like.

The buffer member 157 is not limited to synthetic polymer materials, and is made of biocompatible materials such as polymers such as ultra-high-molecular polyethylene (UHMWPE), and low friction elastomers such as polyurethane. It can be manufactured in various ways. Here, UHMWPE is a PE resin with a very high molecular weight, and its average molecular weight is about 10 times the molecular weight of high-density polyethylene. It has high impact strength that is maintained even at cryogenic temperatures, and has the advantage of not cracking even when a very strong impact (stress) is applied. In addition, because of its high melt viscosity, it is a material excellent in various mechanical properties such as wear resistance, self-lubrication, energy absorption at high stress, and soft deflection temperature. In more detail, the ultra-high-molecular polyethylene (UHMWPE) powder may have a density within 945 as an average value of the result measured according to the immersion method. That is, it may be appropriate when it is specifically 925 to 945 kg/m 3. In addition, the tensile stress (σ _y ) at yield is 18 MPa or more, the tensile stress (σ _R ) at the time of determination is 25 MPa or more, elongation at elongation (εR) is 250% or more, and the hole impact strength (α _CN ) is 25 to It can have a physical property of 126kJ/m².

4A is an assembled cross-sectional view showing a first embodiment of an artificial disk according to an embodiment of the present invention, and FIG. 4B is an assembled cross-sectional view showing a second embodiment of an artificial disk according to an embodiment of the present invention, and FIG. 4C Is an assembled cross-sectional view showing a third embodiment of an artificial disk according to an embodiment of the present invention.

In particular, the first receiving groove 111 and the buffer member 157 may satisfy Equation 1 below.

Here, D _1a denotes a bottom diameter of the buffer member 157 positioned parallel to the first plate 110, and D _1b denotes the bottom face of the buffer member 157 positioned at an angle to the first plate. It means the diameter of the bottom surface forming the intersecting angle, D ₂ means the diameter of the vertical axis of the inlet portion of the first receiving groove 111, D ₃ is the horizontal axis of the inlet portion of the first receiving groove 111 Means the diameter of.

4A to 4C, the first receiving groove 111 may have an elliptical shape having a vertical axis and a horizontal axis having different diameters. That is, the diameter D ₃ based on the horizontal axis of the inlet portion of the first receiving groove 111 can be easily installed even if it is installed in any direction on the bottom surface of the buffer member 157. On the other hand, since the diameter (D ₂ ) based on the vertical axis of the inlet portion of the first receiving groove 111 is smaller than the bottom diameter (D _1a ) of the buffer member 157 located parallel to the first plate 110, FIG. 4B It can be installed at an angle like this. Therefore, there is an advantage that separation between the first plate 110 and the buffer member 157 is not separated after installation. In addition, the artificial disk 100 according to the present invention can be used for a long time by maintaining the shape not to change even with the force received from the movement of the spine after implantation, and reducing frictional shock and noise.

5A is a front view showing a second plate of an artificial disk according to an embodiment of the present invention.

The second plate 170 of the artificial disk 100 according to an embodiment of the present invention has a predetermined thickness and has a curved upper surface and a flat surface, and the height of one surface of the front surface is greater than the height of the surface of the rear surface. I can. Such a structure enables the second plate 170 to move flexibly along the curved surface of the core motion member 150 and efficiently distributes the load applied to the core motion member 150.

5B is a plan view showing a second plate of an artificial disk according to an embodiment of the present invention.

The first fixing protrusion 115 and the second fixing protrusion 175 of the artificial disc 100 according to an embodiment of the present invention are formed in a plurality, one of the vertebrae and the other vertebrae (1) (3). ) May be located on one surface of each of the first plate 110 and the second plate 170 in contact with each other. The first fixing protrusion 115 and the second fixing protrusion 175 have a right triangle shape and are easily fastened when fastened in the B direction, but can be prevented from being separated unless a force is applied by force A. At this time, the distance between the first fixing protrusion 115 and the second fixing protrusion 175 may be arranged narrower from A (front) to B (rear). The radial arrangement of the first fixing protrusion 115 and the second fixing protrusion 175 may have a higher fixing force than a narrow arrangement and a wide arrangement. Therefore, when fastening from A (front) to B (rear), it is easily fastened, but when separating from B (rear) to A (front), it may be difficult to remove without the help of a separate mechanism.

6 is a cross-sectional view showing a core motion member according to a first modified example of an artificial disk according to an embodiment of the present invention, and FIG. 7A is a core motion according to a second modified example of the artificial disk according to an embodiment of the present invention. It is a cross-sectional view showing the member, and FIG. 7B is a plan view showing the rotating part of FIG. 7A. In addition, FIG. 8A is a cross-sectional view showing a core movement member according to a third modified example of an artificial disk according to an embodiment of the present invention, and FIG. 8B is a plan view showing the rotation movement part of FIG. 8A.

6 to 8B, the rotational movement part 155 of the core center member 150 according to the first to third modifications of the artificial disk according to an embodiment of the present invention is inserted into at least a part of The unit 151 may be further included. The lead-in portion 151 may include a hole 155a formed in the center of the rotational movement portion 155. Here, the hole 155a may mean a notch, a groove, a through hole, or the like. In addition, it may include a plurality of dimples 155b that are retracted throughout the rotational movement part 155, and may include a groove 155c that is linearly retracted on the rotational movement part 155. That is, the lead-in portion 151 may include at least one selected from among the holes 155a, dimples 155b, and grooves 155c.

Referring to FIG. 6, the core center member 150 according to the first modified example of the artificial disk according to an embodiment of the present invention may include a hole 155a. On the other hand, when the second receiving groove 171 and the core center member 150 are assembled with each other or processed respectively, point contact occurs due to a tolerance that occurs, and when this part is cracked, friction may increase. However, since the lead-in portion 151 is formed in the core center member 150, surface contact may be achieved, and friction may be reduced compared to point contact. Therefore, even after the procedure, patients can live without restrictions and discomfort in their daily spinal segment activities.

7A and 7B, in the second modification of the artificial disk according to an embodiment of the present invention, the rotational movement part 155 of the core movement member 150 includes a hole 155a and the hole 155a located at the center. A plurality of dimples 155b may be further included in the periphery. The dimple 155b has a shape such as a dimple, which is a small groove formed on the surface of the golf ball, and may have various shapes such as circular, triangular, and polygonal shapes like the hole 155a. As shown in FIG. 7B, a hole 155a is formed in the center of the rotational part 155, and a plurality of dimples 155b such as hemispherical small grooves may be formed in a constant radial arrangement around the rotational part 155. Therefore, it is possible to reduce friction generated due to a processing tolerance between the receiving groove 171 and the rotational movement part 155 and improve the flexibility of the contact. On the other hand, when the spaces between the plurality of dimples 115b are arranged to have a certain balance in the rotational movement unit 155, friction when contacting the second receiving groove 171 may be further reduced.

8A to 8B, the rotational movement part 155 of the core movement member 150 according to the third modified example of the artificial disk 100 according to an embodiment of the present invention has a hole 155a formed through the center. And at least one groove 155c. The hole 155a may accommodate foreign substances such as worn fine powder generated by rubbing the artificial disc 100 by spinal segmental motion. Accordingly, since the inside of the hole 155a accommodates foreign substances and prevents them from escaping to the outside of the artificial disk 100, side effects such as inflammation after the procedure can be reduced.

On the other hand, the artificial disk 100 may be immersed in a spine strengthening agent before installation between the vertebrae 1 and 3 facing each other. At this time, the inlet 151 of the core exercise member 150 may further include a spine strengthening agent. For example, the spine strengthening agent may include various stem cells, medicines, and nucleus, which are accommodated in the inlet 151 to strengthen the lubrication function and the spine.

In particular, stem cells may include, for example, embryonic stem cells, adult stem cells/tissue-specific stem cells, and induced pluripotent cells (iPSCs).

In addition, the at least one groove 155c may serve as a passage through which the spine enhancer stored in the hole 155a flows, so that it can be absorbed by one of the vertebrae facing each other and the other vertebrae (1) (3). . At least one groove 155c may be formed in a linear shape on a curved portion over one side of the core motion member 150. For example, the groove 155c may be linear in four directions from the center. This groove (155c) reduces friction caused by machining tolerances and improves contact flexibility when the rotational movement portion 155 of the core movement member 150 rotates and translates with respect to the second receiving groove 171 I can make it.

9 is an enlarged view of the main part, and is a combined cross-sectional view of FIG. 3.

The artificial disk 100 according to an embodiment of the present invention may include a body 10 on each of the first plate 110 and the second plate 170 and a coating layer 20 thereon. 6 shows that the coating layer 20 is formed on the top of the body 10 of the second plate 170, that is, on the upper surface of the spine in contact with the other spine 3, the body 10 of the first plate 110 The coating layer 20 may be formed on a lower surface, that is, on a bottom surface that contacts any one of the vertebrae 1.

The body 10 of each of the first and second plates 110 and 170 is a metal material of a cobalt-chromium-molybdenum alloy, titanium or titanium alloy, cobalt-chromium alloy, stainless steel. It can be made variously from biocompatible materials such as steel. In detail, the main body 10 may be made of a cobalt-chromium-molybdenum alloy, that is, 19Co28Cr6Mo in the formula. The content of the cobalt-chromium-molybdenum alloy material is 26 to 30% by weight of chromium, 5 to 7% by weight of molybdenum, within 0.75% by weight of iron, and 1% by weight of manganese (Manganese). Within, silicon (Silicon) within 1% by weight, carbon (Carbon) within 0.14% by weight or 0.15 to 0.35% by weight, nickel (Nickel) within 1% by weight, nitrogen (Nitrogen) within 0.25% by weight and cobalt ( Cobalt) may contain 55 to 70% by weight.

In addition, a coating layer 20 coated with at least one of titanium and hydroxyapatite (hereinafter referred to as HA) on one surface of the body 10 in contact with one of the vertebrae and the other vertebrae (1) (3) It may include.

Titanium coating may mean coating with non-alloyed titanium and titanium-aluminum-vanadium alloy (chemical formula: Ti-6Al-4V) powder. In detail, the titanium-aluminum-vanadium alloy powder may include 3 to 10% by weight of aluminum, 1 to 4.5% by weight of vanadium, 85 to 95% by weight of titanium, and 0.11 to 1.76% by weight of other additives. On the other hand, HA coating contains 50 to 79% by weight of hydroxyapatite, 0.5 to 5% by weight of β-TCP, 0.5 to 5% by weight of α-TCP, 0.5 to 5% by weight of TTCP, and 0.5 to 5% of CaO 5% by weight and other additives may be included. In addition, the thickness of the coating layer may be made of 0.01 to 0.2mm. If it is less than the minimum value of 0.01mm, the coating hardness is low and it is weak to scratch, and the original purpose of the coating may be lost. In addition, when it exceeds the maximum value of 0.2mm, the probability of seizure is high and friction may increase during the movement of the core motion part. Therefore, by including the above-described coating layer 20 on the body 10 of the artificial disk 100, the bio-stability of the artificial disk 100 implanted in one of the vertebrae and the other vertebrae (1) (3) ( Biostability), biocompatibility and interfacial compatibility can be improved.

10A is a cross-sectional view showing an operating state of the artificial disk in the C and D directions according to an embodiment of the present invention, and FIG. 10B is a cross-sectional view showing an operating state of the artificial disk in the A direction according to an embodiment of the present invention, and FIG. 10C Is a cross-sectional view showing an operating state of the artificial disk in the B direction according to an embodiment of the present invention.

10A to 10C, in an artificial disk 100 according to an embodiment of the present invention and another embodiment, a second plate 170 is formed with respect to the first plate 110 with the core exercise unit 150 as a center point. It can move forward, backward and left and right. In particular, when considering the anatomical movement of the human body, it is necessary to limit the movement within a specific range. Accordingly, when the second plate 170 flows with respect to the first plate 110, the range of the maximum inner angle θ therebetween may be 20 to 25°. For example, as shown in FIG. 8A, when the second plate 170 contacts the first plate 110 in the C direction when viewed from the front part A of the patient to be treated, the inner maximum angle in the D direction ( The range of θ) may be 20 to 25°. As such, when contacting in the opposite direction D, the range of the maximum internal angle θ in the C direction may be the same.

On the other hand, in the case of a conventional artificial disc having an inner maximum angle (θ) of an upper plate flow angle of 5.77 to 9.02° with respect to the lower plate, the limitation of limiting the segmental motion of the patient's spine after implantation and causing discomfort during segmental motion there was. On the other hand, when the second plate 170 flows with respect to the first plate 110, the range of the maximum internal angle θ therebetween is 20 to 25°. There are no restrictions on daily activities by improving them.

In addition, the artificial disk 100 according to an embodiment of the present invention is a buffer member located in the first receiving groove 111 when the second plate 170 contacts the first plate 110 in the C or D direction ( 157) can move in the opposite D or C direction. The plane movement of the buffer member 157 may prevent the core movement unit 150 from being separated from the second plate 170, alleviate impact, and reduce noise.

In addition, referring to FIG. 10B, in the artificial disk 100, the second plate 170 moves in the direction A with respect to the first plate 110 to represent an inner angle therebetween. In this case, the range of the inner maximum angle θ in the B direction may be 20 to 25°. On the other hand, the artificial disk 100 according to an embodiment of the present invention is controlled when the second plate 170 contacts the first plate 110 in the direction A, that is, when the patient undergoes prone movement. 1 The buffer member 157 located in the receiving groove 111 can move in a plane in the opposite direction B. The plane movement of the buffer member 157 may prevent the core movement unit 150 from being separated from the first plate 110, alleviate impact, and reduce noise.

In addition, referring to FIG. 10C, in the artificial disk 100, the second plate 170 moves in the B direction with respect to the first plate 110 to represent an internal angle therebetween. In this case, the range of the inner maximum angle θ in the A direction may be 20 to 25°. On the other hand, the artificial disk 100 according to an embodiment of the present invention is used when the second plate 170 is in contact with the first plate 110 in the direction B, that is, the patient undergoes an exercise in which the patient is tilted to the rear (rear). At this time, the buffer member 157 located in the first receiving groove 111 may move in a plane in the opposite direction A. The plane movement of the buffer member 157 may prevent the core movement unit 150 from being separated from the second plate 170, alleviate impact, and reduce noise.

Therefore, more preferably, the inner maximum angle θ in the C and D directions is 20.1°, and the inner maximum angle θ in the A and B directions is 24.3°. Therefore, it is possible to minimize the load while allowing the load on the core exercise unit 150 to be evenly distributed. In addition, in consideration of the anatomical movement of the human body, the movement is limited when the range of the inner maximum angle (θ) is 20 to 25˚, and the movement center of the human body and the center according to the movement of the artificial disk 100 quickly coincide with each other. You can do it. In other words, it is possible to minimize the load on the artificial disk 100 by distributing the stress acting on the spine through discontinuous movements due to the inconsistency of the upper and lower spines.

<Artificial disc manufacturing method>

Hereinafter, a method of manufacturing the artificial disk 100 according to the present invention will be described.

The manufacturing method of the artificial disk 100 according to the present invention includes a first plate 110, a second plate 170, and a core installed between one of the vertebrae facing each other and the other vertebrae (1) (3). It may be made of a cushioning member 157 installed between the exercise unit 150 and the first plate 110 and the core exercise unit 150.

First, in order to manufacture the first plate 110, a plurality of first fixing protrusions 115 are formed on one surface of the vertebrae in contact with one of the vertebrae 1, and a pair of semicircles are spaced apart from each other at a predetermined interval and It is possible to manufacture the first plate 110 in which the first receiving groove 111 having a shape in which the extension part 117 is extended is formed therebetween. At this time, the first plate 110 may have an elliptical shape in which the horizontal length of the first receiving groove 111 is longer than the vertical length because the extension portion 117 is provided. In such a structure, when the buffer member 157 or the core movement unit 150 is inserted into the first plate 110, it can be easily inserted into the horizontal axis of the first receiving groove 111 in any direction. On the other hand, the buffer member 157 or the core movement unit 150 may be installed at an angle on the vertical axis, and separation and separation after installation is difficult. Therefore, it is easy to insert and fasten the core movement member 150 to the first plate 110, but it is possible to prevent separation after implantation. In addition, there are no restrictions on the activities of daily life by improving the surgical indications and motility of the spinal segment of patients after transplantation.

The second plate 170 includes a second plate 170 having a plurality of second fixing protrusions 175 formed on one surface of the vertebrae in contact with the other vertebrae 3 and having a second receiving groove 171 formed on the other surface of the second plate 170. Can be manufactured.

The core movement unit 150 is formed in a curved surface on the upper side and a rotation movement unit 155 in which the second plate 170 rotates relatively, and a plane is formed on the lower side in which the first plate 110 moves relatively flat. It can be manufactured to include a neck portion 153 formed on the side is interposed between the movement unit 157 and the rotation movement unit 155 and the planar movement unit 157.

In addition, in the step of manufacturing the core movement unit 150, the rotation movement unit 155 includes a hole 155a recessed in the center of the curved portion, and a plurality of dimples recessed throughout the curved portion. ) (155b) and at least one of at least one groove 155c formed in a linear shape on a portion formed in a curved surface may be further included. Here, the groove 155c may be formed over the entire side of the core motion member 150.

In addition, the buffer member 157 is installed between the first plate 110 and the core movement member 150, and a third receiving groove 151 is formed therein, and the first plate with respect to the core movement member 150 (110) can be made of an elastic material that relieves impact and noise during relatively flat motion. Accordingly, the buffer member 157 may prevent separation of the core movement member 150 from the first plate 110 during plane movement, alleviate impact, and reduce noise.

The first plate 110, the second plate 170, and the core motion member 150 can be buffered by reducing friction and noise caused by impact by using other materials having superior elastic properties than the core motion member 150. ) Can be prevented from separating, alleviate impact, and reduce noise.

The processing method of each of the first plate 110, the second plate 170, the core movement member 150, and the buffer member 157 described above can be manufactured by various manufacturing methods such as mold making and molding by 3D printing. have.

In addition, each of the first plate 110, the second plate 170, the core motion member 150 and the buffer member 157 has excellent biocompatibility such as ceramics, synthetic polymers, metals, and biopolymer materials. It is a material having excellent compressive strength and abrasion resistance and can be manufactured by selecting variously. In particular, the cushioning member 157 may be made of a synthetic polymer material that is more suitable for buffering impact and noise caused by movement between the core movement member 150 and the first plate 110 while having durability.

Finally, the artificial disk 100 can be completed, including the step of inserting and installing the integrated core movement member 150 and the buffer member 157 between the first plate 110 and the second plate 170 and finally assembling. I can.

11 is an exploded view showing an artificial disk according to another embodiment of the present invention, and FIG. 12 is an exploded cross-sectional view taken along line XII-XII of FIG. 11.

11 and 12, an artificial disk 200 according to another embodiment of the present invention includes a first plate 110 installed in contact with any one of the vertebrae 1, and the other of the vertebrae ( It may include a second plate 170 installed in contact with 3) and a core motion member 250 installed between the first and second plates 110 and 170. Here, each of the members of the artificial disc 200 performs substantially the same configuration, function, and role in the case of members having the same reference numerals mentioned in FIGS. 1 to 10C. Therefore, in order to avoid redundant description, a detailed description of members having the same reference numerals has been described above and will be omitted.

On the other hand, compared with the embodiment shown in FIGS. 1 to 10C, the core motion member 250 may be contrasted. The core movement member 250 may be located between the first receiving groove 111 and the second receiving groove 171. It is possible to reduce impact and noise while relatively moving in a plane with respect to the first plate 110, and to rotate relative to the second plate 170. In detail, the core movement member 250 may include a rotation movement part 255, a flange part 257, and a neck part 253. The rotational movement part 255 is installed in contact with the second receiving groove 271 and is formed in a curved surface so that the rotational movement with respect to the second plate 270 is possible. The flange portion 257 is located on the lower surface of the core movement member 250 and is installed in contact with the first receiving groove 111 and moves relatively flat with respect to the first plate 110 while the first receiving groove 111 ) To prevent departure and reduce impact and noise. The neck portion 253 is interposed between the rotational movement portion 255 and the flange portion 257, and is locked in the first receiving groove 111 so that the flange portion 257 can be aligned and installed, and the core movement member 250 It can play a role of reducing the impact during the plane movement of In addition, the neck portion 253 may be locked to the side of the first receiving groove 211 while the flange portion 257 supports the load of the rotational movement portion 255. That is, as the neck portion 253 has a load and a larger area than the flange portion 257 in an area of the rotational movement portion 255, it may balance and support the load.

In particular, the first receiving groove 111 and the flange portion 257 may satisfy Equation 2 below.

Here, C _1a (not shown) refers to the bottom diameter of the flange portion 257 located parallel to the first plate 110, and C _1b (not shown) is at an angle to the first plate 110 It means the diameter of the bottom surface forming an angle between the bottom surface of the flange portion 257 positioned so that D ₂ is the diameter based on the vertical axis of the inlet portion of the first receiving groove 111, and D ₃ is the first It refers to the diameter of the horizontal axis of the entrance portion of the receiving groove 111 as a reference.

Although not shown, the first receiving groove 111 may form an elliptical shape having different diameters of the vertical axis and the horizontal axis. That is, the diameter D ₃ based on the horizontal axis of the inlet portion of the first receiving groove 111 can be easily installed even if it is installed in any direction on the bottom surface of the flange portion 257. On the other hand, since the diameter (D ₂ ) based on the vertical axis of the entrance portion of the first receiving groove 111 is smaller than the bottom diameter (C _1a ) of the flange portion 257 located parallel to the first plate 110, Can be installed. Therefore, there is an advantage that separation between the first plate 110 and the flange portion 257 is not separated after installation.

The core motion member 250 may be made of ceramic. In particular, the rotational movement part 255 and the neck part 253 may be made of ceramic, and the flange part 257 may be made of a biocompatible synthetic polymer material. At this time, the flange portion 257 may be manufactured to be positioned under the core motion member 250 by a method such as thermosetting, injection molding, caulking, or the like. That is, the rotational movement part 255 and the neck part 253 are made of a ceramic material that is stronger in mechanical strength, and the flange part 257 is durable and buffers impact and noise caused by movement between the first plates 110. It is possible to use a more suitable synthetic polymer material. Therefore, the rotational movement part 255, the neck part 253, and the flange part 257 are made of materials of mutually complementary properties to absorb impact and reduce noise even after installation, so that they can be used for a long time. However, the present invention is not limited thereto, and each of the rotational movement part 255, the neck part 253, and the flange part 257 may be made of the same material.

In addition, the rotational movement unit 255 may have a first modification to a third modification as shown in FIGS. 6 to 8B. That is, the rotational movement unit 255 may further include at least one of a hole 155a, a plurality of dimples 155b, and at least one groove 155c. Therefore, it is possible to reduce the friction between the second receiving groove 171 and the rotational movement part 255 and improve the flexibility of the contact. In addition, after transplantation, patients' surgical indications and motility of spinal segments can be improved, resulting in unrestricted effects on daily activities.

The above-described embodiments are merely exemplary, and various modifications and other equivalent embodiments are possible from those of ordinary skill in the art to which the present invention pertains. Therefore, the true technical scope of the present invention should be determined by the technical spirit of the invention described in the claims.

1: one of the vertebrae 3: the other of the vertebrae
10: main body 20: coating layer
100, 200: artificial disc 110: first plate
111: first accommodation groove 113: semicircle
115: first fixing protrusion 117: extension
119: first tool groove 130: buffer member
131: third receiving groove 150: core movement member
151: entry part 153: neck part
155: rotary motion part 155a: hole
155b: dimple 155c: groove
157: plane movement part 170: second plate
171: second receiving groove 175: second fixing protrusion
179: second tool groove 250: core moving member
253: neck portion 255: rotation movement portion
257: flange portion

Claims (16)

In the artificial disc installed between the vertebrae facing each other,
It is installed in contact with one of the vertebrae, and has at least one first fixing protrusion formed on one surface of the vertebrae in contact with any one of the vertebrae to prevent separation, and a first receiving groove is formed on the other surface. With 1 plate;
It is installed in contact with the other of the vertebrae, and has at least one second fixing protrusion formed on one surface in contact with the other vertebrae of the vertebrae to prevent separation, and a second receiving groove is formed on the other surface. With two plates;
A core movement member positioned between the first receiving groove and the second receiving groove and moving so that the second plate can relatively move in plane and rotate relative to the first plate; And
It is installed between a portion of the core movement member and the first plate, and a third receiving groove is formed therein, and a cushioning cushion that relieves shock and noise when the first plate moves relatively flat with respect to the core movement member. An artificial disc containing a member. The method of claim 1,
The first receiving groove,
A pair of semicircular portions having an outer shape of a semicircular shape and formed to be spaced apart from each other at predetermined intervals;
An artificial disk, characterized in that it comprises an extension formed extending in the spaced portion between the pair of semicircular portions. The method of claim 1,
The core movement member,
A planar movement unit installed in contact with the buffer member and configured to move in a relatively flat plane with respect to the first plate together with the buffer member;
A rotation movement part connected to the plane movement part and installed in the second receiving groove, and formed in a curved surface so that the second plate rotates relative to the core movement member; And
And a neck portion interposed between the planar motion part and the rotational motion part, and configured to lock the side surface of the first receiving groove while supporting the load of the rotational motion part. The method of claim 3,
The core movement member
Artificial disk, characterized in that it further comprises a lead-in portion formed in at least a portion of the rotational movement. The method of claim 4,
The inlet,
An artificial disk comprising at least one selected from a hole formed in the center of the rotational movement unit, a plurality of dimples recessed throughout the rotational movement unit, and a groove formed linearly on the rotational movement unit. The method of claim 5,
An artificial disk, characterized in that it further comprises a spine strengthening agent that is accommodated in the inlet and strengthens the lubrication function and the spine. The method of claim 1,
The core motion member is made of ceramic, and the buffer member is an artificial disk, characterized in that made of a synthetic polymer material. The method of claim 1,
The second plate,
An artificial disk having a predetermined thickness, wherein the upper part forms a curved surface and the lower part forms a flat surface, and the height of one side of the front side is greater than the height of the side of the rear side. The method of claim 1,
A plurality of the first and second fixing protrusions are formed, and are located on one surface of each of the first plate and the second plate in contact with one of the vertebrae and the other vertebrae,
Artificial disk, characterized in that the space between the first and second fixing projections are arranged narrower from the front to the rear. The method according to any one of claims 1 to 9,
Each of the first plate and the second plate includes a body made of a metallic material of a cobalt-chromium-molybdenum alloy; And
An artificial disc comprising a coating layer coated with at least one of titanium and hydroxyapatite on one surface of the body in contact with one of the vertebrae and the other vertebrae. The method according to any one of claims 1 to 9,
An artificial disk, characterized in that, when the second plate moves with respect to the first plate, the range of the maximum inner angle therebetween is 20 to 25°. In the artificial disc installed between the vertebrae facing each other,
It is installed in contact with one of the vertebrae, and has at least one first fixing protrusion formed on one surface of the vertebrae in contact with any one of the vertebrae to prevent separation, and a first receiving groove is formed on the other surface. With 1 plate;
A second plate having at least one second fixing protrusion formed on one surface of the vertebrae in contact with the other vertebrae to prevent separation, and having a second receiving groove formed on the other surface;
A core motion member positioned between the first receiving groove and the second receiving groove, reducing impact and noise while moving relatively flat with respect to the first plate, and rotating relative to the second plate. And
The core movement member,
A rotation movement unit installed in contact with the second receiving groove and formed in a curved surface to rotate relative to the second plate;
A plan that is located on the lower surface of the core movement member and is installed in contact with the first receiving groove and moves relatively flat with respect to the first plate to prevent separation from within the first receiving groove and reduce impact and noise chapter; And
It characterized in that it comprises a neck portion interposed between the rotational movement portion and the flange portion, locking the first receiving groove so that the flange portion can be installed in accordance with, and reduce the impact and noise during the plane movement of the core movement member. Artificial disc. The method of claim 12,
The hole said core movement member
Artificial disk, characterized in that it further comprises a lead-in portion formed in at least a portion of the rotational movement. The method of claim 12,
The first receiving groove,
A pair of semicircular portions having an outer shape of a semicircular shape and formed to be spaced apart from each other at predetermined intervals;
An artificial disk, characterized in that it comprises an extension formed extending in the spaced portion between the pair of semicircular portions. In the method of manufacturing an artificial disk comprising a first plate, a second plate, a core movement member installed between the vertebrae facing each other, and a buffer member installed between the first plate and the core movement member,
A first plate in which a plurality of first fixing protrusions are formed on one surface of the vertebrae in contact with one of the vertebrae, and a pair of semicircles are spaced apart from each other by a predetermined interval, and a first receiving groove having an extension part extending therebetween is formed. Manufacturing a;
Manufacturing a second plate having a plurality of second fixing protrusions formed on one surface of the vertebrae in contact with the other vertebrae and having a second receiving groove formed on the other surface;
It is formed in a curved surface on the upper side and the rotation movement part for relatively rotating movement of the second plate, and a plane movement part formed in a plane on the lower side for relatively plane movement of the first plate, and interposed between the rotation movement part and the plane movement part Manufacturing a core motion member including a neck portion formed on a side surface;
It is installed between the first plate and the core movement member, and a third receiving groove is formed therein, and the first plate is made of an elastic material that relieves impact and noise when the first plate is relatively flat with respect to the core movement member Manufacturing a buffer member; And
And inserting and installing the core moving member and the buffer member integrated between the first plate and the second plate to finally assemble the disk. The method of claim 15,
The step of manufacturing the core motion member,
Hole The method of manufacturing an artificial disk, characterized in that it further comprises a lead-in portion formed in at least a portion of the rotational movement.

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