KR20180020664A - 2 component type cosmetic composition - Google Patents

Abstract

The present specification relates to a two-component type cosmetic composition which includes: a first agent including an acidic polymer, an alpha-hydroxy acid and an active ingredient; and a second agent including carbonate and a thickening agent. Accordingly, the present invention can improve safety without skin irritation.

Description

2-component type cosmetic composition < RTI ID = 0.0 >

The present specification describes a two-pack cosmetic composition.

When a component stable at low pH is used among the active ingredients used for exerting an effect in a cosmetic, various methods for stably incorporating such an active ingredient into the cosmetic are considered. When the pH of the cosmetic is lowered by incorporating an acidic substance into the cosmetic, problems of irritation may occur when the skin is used, and it may be difficult to maintain the viscosity in a cosmetic having a low pH. Accordingly, such an active ingredient is generally used as a solubilized formulation, and it is difficult to realize a formulation having an appropriate viscosity.

Thus, there is a need for a composition that can stably incorporate an effective ingredient stable at low pH in a formulation while having excellent skin safety, and can realize a composition having a desired viscosity.

In view of the above, a problem to be solved by the present invention is to provide a cosmetic composition which contains an active ingredient stable at a low pH and is safe without skin irritation.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition excellent in long-term stability and high-temperature stability.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition which is realized with a desired viscosity.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition excellent in feeling of use.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition having improved skin absorbency.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition stably containing an active ingredient stable at low pH.

In one aspect, the present invention provides a pharmaceutical composition comprising a first agent comprising an acidic polymer, an alpha-hydroxy acid and an active ingredient; And a second agent comprising a carbonate and a thickening agent.

In one aspect, the present invention can provide a cosmetic composition which contains a stable active ingredient at a low pH and is highly safe without skin irritation.

In another aspect, the present invention can provide a cosmetic composition excellent in long-term stability and high-temperature stability.

In yet another aspect, the present invention can provide a cosmetic composition that is implemented with a desired viscosity.

From another viewpoint, the present invention can provide a cosmetic composition excellent in feeling of use.

In another aspect, the present invention can provide a cosmetic composition having improved skin absorbency.

In another aspect, the present invention can provide a cosmetic composition stably containing an active ingredient stable at low pH.

FIG. 1 is a graph showing a change in viscosity of a first agent of the composition according to an embodiment of the present invention over time. FIG.

Hereinafter, embodiments of the present invention will be described in more detail. However, the techniques disclosed in the present application are not limited to the embodiments described herein but may be embodied in other forms. It should be understood, however, that the embodiments disclosed herein are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit and scope of the invention.

The cosmetic composition according to one embodiment of the present invention can stably contain an active ingredient stable at low pH in a formulation. In this embodiment, the cosmetic composition comprises a first agent having a low pH and a second agent containing the active ingredient and having a viscosity and a pH different from that of the first agent, wherein the first agent and the second agent are mixed It is possible to provide a cosmetic composition which is excellent in stability during storage and excellent in use feeling and skin safety.

The first agent may comprise an acidic polymer, an alpha-hydroxy acid and an active ingredient.

The first agent exhibits a weakly acidic pH, so that the active ingredient can be stably maintained, and the viscosity can be stably maintained at a low pH over time, so that the formulation stability can be excellent.

The first agent may, for example, have a pH of from 3 to 5.

The first agent may have a viscosity of 20000 cps or more, 21000 cps or more, 22000 cps or more, 23000 cps or 24000 cps or more, 30,000 cps or less, 29000 cps or less, 28000 cps or less, 27000 cps or less, 26000 cps or 25000 cps, To 30000 cps, for example, 20000 cps to 25000 cps, and the viscosity can be maintained over time within the viscosity range. The active ingredient can be stably maintained in the first gelatin having the high viscosity as described above, a formulation having excellent feeling of use can be realized, and it can be easily discharged from the airless container.

The acidic polymer can stably maintain the viscosity of the formulation under a slightly acidic condition and can stably maintain the active ingredient. The acidic polymer may be, for example, polyacrylate crosspolymer-6.

Wherein the acidic polymer is present in an amount of at least 0.5 wt%, at least 0.6 wt%, at least 0.7 wt%, at least 0.8 wt%, at least 0.9 wt%, at least 1 wt%, at least 1.5 wt% At least 15 wt.%, At most 14 wt.%, At most 13 wt.%, At least 12 wt.%, At least 2.5 wt.%, At least 3 wt.%, At least 3.5 wt.%, At least 4 wt. Up to 11 wt.%, Up to 9 wt.%, Up to 8 wt.%, Up to 7 wt.% Or up to 6 wt.%, Such as from 0.5 wt.% To 15 wt.%, 10% by weight. Within the above range, the viscosity of the formulation can be stably maintained at a slightly acidic state, and the active ingredient can be stably contained.

The alpha-hydroxy acid can stably contain the active ingredient by keeping the pH of the first agent slightly acidic. For example, it may be at least one selected from malic acid, lactic acid, glycolic acid and citric acid, but is not limited thereto.

The alpha-hydroxy acid is present in an amount of at least 0.5 wt%, at least 0.6 wt%, at least 0.7 wt%, at least 0.8 wt%, at least 0.9 wt%, or at least 1 wt% 9.5% or less, 9% or less, 8.5% or less, 8% or less, 7.5% or less, 7% or less, 6.5% or less, 6% or less, 5.5% , 4.5 wt% or less, or 4 wt% or less, such as 0.5 wt% to 10 wt%, such as 1 wt% to 5 wt%. Within this range, the active ingredient can be stably contained in the first agent.

The active ingredient may be any substance which is stable at low pH, for example, it may be a stable substance at a pH of 3 to 5, for example, trisodium fructose diphosphate, ethyl ascorbic acid (ethyl but are not limited to, ascorbic acid, epigallocatechin gallate (EGCG), ascorbyl glucoside, and the like.

The active ingredient may be contained in an amount of 0.05 to 5% by weight, for example, 0.2 to 2% by weight based on the total weight of the first agent, and may exhibit efficacy within the above range, It can be excellent.

The second agent may include a carbonate and a thickener.

The second agent can neutralize the pH of the first agent to solve the skin irritation problem during use, exhibit a viscosity different from that of the first agent, and can adjust the viscosity when used as a mixed agent, thereby providing a cosmetic composition excellent in feeling of use.

The second agent exhibits weak alkalinity. When the second agent is mixed with the second agent, the pH is elevated through neutralization to provide a highly safe composition free from skin irritation. Also, when mixed with the first agent, CO- ₂ is generated to enhance the skin absorption power, viscosity of the mixture can be lowered, viscosity can be adjusted, and a smooth and refreshing feeling can be provided.

The second agent may have a pH of, for example, 9 to 10.

The second agent preferably has a viscosity of at least 10,000 cps, at least 11,000 cps, at least 12,000 cps, at least 13,000 cps, at least 14,000 cps, at least 15,000 cps, at least 16,000 cps, at least 17,000 cps, at least 18,000 cps, at most 20,000 cps, at most 19,000 cps, at most 18,000 cps, , Or 16000 cps or less, and may be, for example, 10000 cps to 20000 cps, for example, 15000 cps to 20000 cps. In one example, as a formulation having a viscosity lower than that of the first agent, the formulation is stable within the above range and can provide excellent feeling of use and can be easily discharged from an airless container.

The carbonate may neutralize the pH of the first agent, and when mixed with the first agent, CO- ₂ may be generated to enhance skin absorption. In addition, when mixed with the first agent, the viscosity of the mixed agent is lowered to provide a smooth and refreshing feel.

The carbonate may be, for example, ammonium carbonate, potassium carbonate, sodium carbonate, magnesium carbonate, potassium carbonate, zinc carbonate, aminoguanidine peanate, ammonium hydrogen carbonate, arginine bicarbonate, silver bicarbonate, sodium bicarbonate, potassium hydrogen carbonate, potassium sesquicarbonate , Calcium sesquicarbonate, and sodium sesquicarbonate may be used.

The carbonate is present in an amount of at least 0.1 wt%, at least 0.2 wt%, at least 0.3 wt%, at least 0.4 wt%, at least 0.5 wt%, at least 0.6 wt%, at least 0.7 wt% , At least 0.9%, at least 1%, at least 1.5%, at least 2%, at least 2.5%, at least 3%, at least 3.5%, at least 4%, at least 4.5% By weight, up to 9% by weight, up to 8.5% by weight, up to 8% by weight, up to 7.5% by weight, up to 7% by weight, up to 6.5% by weight, up to 6% By weight to 9% by weight, for example, 0.5% by weight to 6% by weight. Within this range, it is possible to provide a safe composition without skin irritation when used, and when the first and second additives are mixed, the absorption of the skin through CO ₂ generation can be enhanced.

The thickener gradually increases the stability of the second agent and can achieve an appropriate viscosity.

The thickener may be a commonly used thickener such as natural gums such as locust bean gum, gum arabic, tamarind gum, pectin, guar gum and xanthan gum, cellulose gum, carbomer, hydroxyethyl cellulose, poly Polyvinyl alcohol, polyvinyl acetate, acrylate / C10-30 alkyl acrylate crosspolymer, sodium polyacrylate, ammonium acryloyldimethyltaurate / vpicopolymer, hydroxypropylstarchphosphate, polyacrylate-13 / Polyacrylate-13, hydroxyethylacrylate / sodium acryloyldimethyltaurate copolymer, phage-240 / HCI copolymer bisdecyltestrashe-2-ethyl, polyacrylic acid- But are not limited thereto. In an embodiment, the second thickener may be an enhancer other than the amide-based, amine-based or ammonium-substituted polymer in the above-mentioned increments from the standpoint of stability at high pH and prevention of bad odor.

The agglomerating agent may be present in an amount of 0.5 wt% or more, 0.6 wt% or more, 0.7 wt% or more, 0.8 wt% or more, 0.9 wt% or more or 1 wt% or more, 10 wt% or less, 9.5 wt% Not more than 9 wt%, not more than 8.5 wt%, not more than 8 wt%, not more than 7.5 wt%, not more than 7 wt%, not more than 6.5 wt%, not more than 6 wt%, not more than 5.5 wt% By weight or less, or 4% by weight or less, for example, 0.5% by weight to 10% by weight, for example, 2% by weight to 5% by weight. The second agent can be stably maintained within the above range, and the viscosity of the mixture can be easily controlled.

In another embodiment, the second agent may further comprise at least one of a surfactant, oil, and wax. The oil and the wax may further include at least one of the oil and the wax to maximize the visible effect due to the generation of CO ₂ and improve the shielding effect of the effective substance to improve skin absorption.

The surfactant may be, for example, arachidyl alcohol / behenyl alcohol / arachidyl glucoside, cetearyl alcohol * Cetearyl glucoside, C14-22 alcohol * C12-20 alkyl glucoside (C14-22 ALCOHOLS * C12-20 ALKYL GLUCOSIDE), glyceryl stearate * PEG-100 stearate, sorbitan series, glucose series, sucrose & other sugar, But are not limited to, PEG ester, PEG ether, PEG glycerol ester, PEG-sorbitan, Ionic SAA, lecithin series. The surfactant may include, for example, 5% by weight to 10% by weight based on the total weight of the second agent.

The oil or wax may be, for example, natural oil, ester oil, PEG, PPG, silicone oil, hydrocarbon oil and the like, and examples thereof include jojoba seed oil, isopropyl palmitate, cyclopentasiloxane * cyclohexasiloxane, - caprylate / caprate, caprylic / capric triglyceride, and the like. The oil or wax may contain, for example, 8 to 15% by weight based on the total weight of the second agent.

The first agent and the second agent may be contained in a weight ratio of 1: 5 to 5: 1, 1: 3 to 3: 1, for example, 1: 1. Within the above range, there is no skin irritation of the mixture, the stability is excellent, and the feeling of use is excellent.

In the cosmetic composition according to the embodiments of the present invention, the first agent and the second agent may be mixed and used by applying a mixed agent.

The pH of the mixture may be from 5 to 6. Within this range, safety can be excellent without skin irritation.

The viscosity of the mixture may be, for example, 10000 cps or more, 11000 cps or more, 12000 cps or more, 13000 cps or more, or 14000 cps or more, 15000 cps or less, 14000 cps or less, 13000 cps or 12000 cps or less and 10000 cps to 15000 cps. The viscosity of the mixture is lowered as described above, so that a soft and refreshing feel can be provided.

The cosmetic composition according to the embodiments of the present invention is excellent in high temperature stability and can maintain a constant viscosity over a wide temperature range.

The cosmetic composition according to embodiments of the present invention may be formulated containing a cosmetically or dermatologically acceptable medium or base. It may be in the form of a suspension, a microemulsion, a microcapsule, a microgranule or an ionic (liposome) and a non-ionic follicular dispersion, or a cream, a skin, a lotion, a powder, an ointment, a spray, May be provided in the form of a stick. It can also be used in the form of a foam or in the form of an aerosol composition further containing a compressed propellant. These compositions may be prepared according to conventional methods in the art.

The cosmetic composition according to embodiments of the present invention can be used as a cosmetic composition in the form of a lipid, an organic solvent, a solubilizing agent, a thickening agent, a gelling agent, an antioxidant, a suspending agent, a stabilizer, a foaming agent, Such as an emulsifier, a nonionic emollient, a filler, a sequestering agent, a chelating agent, a preservative, a vitamin, a barrier, a wetting agent, a dye, a pigment, a hydrophilic or lipophilic active agent, a lipid vesicle or any other ingredient commonly used in cosmetics May contain adjuvants commonly used in the field of cosmetics or dermatology. Such adjuvants are introduced in amounts commonly used in the cosmetics or dermatological fields.

Hereinafter, the present invention will be described in detail with reference to Examples, Comparative Examples and Test Examples. It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not to be construed as limiting the scope of the present invention. It will be self-evident.

[Examples and Comparative Examples] Preparation of two-part cosmetic composition

Two-part cosmetic compositions of Example 1 and Comparative Example 1 were prepared according to the composition shown in Table 1 below.

(weight%) Ingredients Example 1 Comparative Example 1 The first agent Deionized water (D.I Water) To 100 To 100 Glycolic acid One One Lactic acid One One Ethyl ascorbic acid (3-O-Ethyl Ascorbic Acid) 2 2 Polyacrylate Crosspolymer-6 1.5 - Sodium carbomer - 1.5 Second article Deionized water (D.I Water) To 100 To 100 Cetearyl Alcohol * Cetearyl Glucoside (CETEARYL ALCOHOL * CETEARYL GLUCOSIDE) 2 2 Arachidyl alcohol / behenyl alcohol / arachidyl glucoside (ARACHIDYL ALCOHOL / BEHENYL ALCOHOL / ARACHIDYL GLUCOSIDE) 3 3 Simmondsia Chinensis (Jojoba) Seed Oil) One One Isopropyl palmitate (ISOPROPYL PALMITATE) One One Cyclopentasiloxane (Cyclopentasiloxane * Cyclohexasiloxane) 2 2 - Caprylate / Caprate (Coco-Caprylate / Caprate) 3 3 Caprylic / Capric triglyceride Caprylic / Capric) Triglyceride 4 4 Polyacrylate-13 & Polyisobutene * Polysorbate 20 (Polyacrylate-13 * Polyisobutene * Polysorbate 20) One One Xanthan gum 0.3 0.3 Sodium bicarbonate 6 6

[Test Example 1] Evaluation of viscosity change at low pH

In order to evaluate the stability with time of the first agent having a low pH in the above Examples and Comparative Examples, the viscosity with time was measured and the results are shown in FIG. The viscosity was measured using a rotary viscometer (Kinexus Ultra +, Malvern Instrument) and the viscosity was measured at 30 ° C for 5 weeks.

1, the viscosity of Comparative Example 1 using a carbomer was lowered with time, while the composition of Example 1 was kept constant without significant viscosity change, so that the composition was stably maintained even at a low pH .

[Test Example 2] Evaluation of viscosity of a mixed material

The viscosity changes at the time of mixing the two-pack type compositions of the above Examples and Comparative Examples were confirmed and are shown in Table 3 below. The viscosity was measured using a rotary viscometer (Kinexus Ultra +, Malvern Instrument) at 26 ° C.

Viscosity (cps) The first agent Second article mixture Example 1 12447 23596 14595 Comparative Example 1 13086 23596 18796

From the results of Table 2, it can be seen that the viscosity of the mixture in Comparative Example 1 is relatively high at the average viscosity of the first agent and the second agent, while in the case of Example 1, the average value of the viscosity of the first agent and the second agent is It can be confirmed that the lower viscosity shows a decrease in viscosity.

[Test Example 3] Sensory evaluation

Eight of the trained professional panel were applied to the inside of the arm and the six examples of evaluation items of thickness, adhesion, softness, moisture, moisture, (1 - very poor, 5 - excellent), and the results are shown in Table 3.

Thickness A sense of closeness Softness Moisture Moistness Residual feeling Example 1 4.5 3.8 4.5 3.1 4.5 3.7 Comparative Example 1 2.1 1.8 3.5 3.5 2.5 2.1

From the results shown in Table 3, it can be confirmed that the compositions of the Examples show significantly better feeling in terms of thickness, adhesion, softness, moisture, moisturization and residual feeling as compared with the compositions of the Comparative Examples.

Claims (18)

A first agent comprising an acidic polymer, an alpha-hydroxy acid and an active ingredient; And
And a second agent comprising a carbonate and a thickening agent. The method according to claim 1,
Wherein the first agent has a pH of from 3 to 5. The method according to claim 1,
Wherein the second agent has a pH of 9-10. The method according to claim 1,
Wherein the first agent has a viscosity of 20,000 cps to 30,000 cps. The method according to claim 1,
Wherein the second agent has a viscosity of from 10,000 cps to 20,000 cps. The method according to claim 1,
Wherein the acidic polymer is polyacrylate crosspolymer-6. The method according to claim 1,
Wherein the thickener comprises a natural gum. 8. The method of claim 7,
Wherein the natural gums are selected from locust bean gum, gum arabic, tamarind gum, pectin, guar gum and xanthan gum. The method according to claim 1,
Wherein the alpha-hydroxy acid is selected from malic acid, lactic acid, glycolic acid and citric acid. The method according to claim 1,
The carbonate may be selected from the group consisting of ammonium carbonate, potassium carbonate, sodium carbonate, magnesium carbonate, potassium carbonate, zinc carbonate, aminoguanidine peanate, ammonium bicarbonate, arginine bicarbonate, silver bicarbonate, sodium bicarbonate, potassium hydrogen carbonate, potassium sesquicarbonate, Calcium sesquicarbonate and sodium sesquicarbonate. The method according to claim 1,
Wherein the pH of the mixture of the first and second agents is 5 to 6. The method according to claim 1,
Wherein the viscosity of the mixture of the first and second agents is from 10000 cps to 15000 cps. The method according to claim 1,
Wherein the first and second agents are present in a weight ratio of 1: 5 to 5: 1. The method according to claim 1,
Wherein the acidic polymer comprises from 1% to 10% by weight relative to the total weight of the first agent. The method according to claim 1,
Wherein the alpha-hydroxy acid comprises from 1 wt% to 5 wt%, based on the total weight of the first agent. The method according to claim 1,
Wherein the carbonate comprises from 0.5% to 6% by weight based on the total weight of the second agent. The method according to claim 1,
Wherein the thickener comprises from 2% to 5% by weight based on the total weight of the second agent. The method according to claim 1,
Wherein the second agent further comprises at least one of a surfactant, an oil, and a wax.

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