KR20150131440A - Needle type blood sugar sensor and the manufacturing method of the same - Google Patents

Needle type blood sugar sensor and the manufacturing method of the same Download PDF

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KR20150131440A
KR20150131440A KR1020140057813A KR20140057813A KR20150131440A KR 20150131440 A KR20150131440 A KR 20150131440A KR 1020140057813 A KR1020140057813 A KR 1020140057813A KR 20140057813 A KR20140057813 A KR 20140057813A KR 20150131440 A KR20150131440 A KR 20150131440A
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sensor
needle
blood glucose
blood sugar
insulin
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윤치성
이혜정
이홍균
방호연
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주식회사 에이엠피올
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    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
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    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose

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Abstract

According to the present invention, a needle type blood sugar sensor can reduce a pain occurring when a needle is inserted into a body when a user wears the blood sugar sensor, because only one needle is needed to measure blood sugar. Also, since only one needle is inserted to measure blood sugar, a wound in a skin is reduced. Also, dangerous situations such as a hypoglycemia shock or the like can be prevented in advance since insulin can be immediately injected in accordance with the blood sugar measured in a sensor unit.

Description

레이저 가공을 통한 니들형 혈당센서 제조방법 및 니들형 혈당센서{Needle type blood sugar sensor and the manufacturing method of the same }[0001] The present invention relates to a needle type blood sugar sensor and a needle type blood sugar sensor,

본 발명은 레이저 가공을 통한 니들형 혈당센서 제조방법 및 니들형 혈당센서에 관한 것으로서, 보다 상세하게는 사용이 간편하고 사용시 고통이 저감될 수 있는 레이저 가공을 통한 니들형 혈당센서 제조방법 및 니들형 혈당센서에 관한 것이다. The present invention relates to a needle type blood glucose sensor manufacturing method and a needle type blood glucose sensor through laser processing, and more particularly, to a needle type blood glucose sensor manufacturing method by laser processing which is simple in use and can reduce pain at the time of use, Blood glucose sensor.

일반적으로 혈당(blood sugar)은 혈액 속에 함유되어 있는 포도당을 의미한다. 당뇨병은 인슐린의 분비량이 부족하거나 정상적인 기능이 이루어지지 않는 등의 대사질환의 일종으로 혈중 포도당의 농도가 높아지는 고혈당을 특징으로 하며, 고혈당으로 인하여 여러 증상 및 징후를 일으키게 된다. 당뇨병 환자의 경우 혈당 측정기를 상시 휴대하고, 주기적으로 혈당량을 체크하여 건강상태를 체크하거나 주치의에게 제공해야 한다. In general, blood sugar refers to glucose contained in the blood. Diabetes mellitus is a type of metabolic disease that lacks insulin secretion or does not function normally. It is characterized by hyperglycemia in which the concentration of glucose in the blood increases. Hyperglycemia causes various symptoms and signs. If you have diabetes, you should carry your blood glucose meter at all times, check your blood sugar regularly, check your health, or give it to your doctor.

그러나, 종래에는 환자인 사용자가 혈당량을 휴대용 혈당 측정기를 이용하여 매번 체크하여 사용하는 것이 번거로울 뿐만 아니라 체크한 혈당량을 메모해두어야 하기 때문에 사용이 불편한 문제점이 있다. However, conventionally, it is troublesome for the user, who checks and uses the blood sugar amount every time using the portable blood glucose meter, because the user who is the patient has to record the amount of the blood glucose checked, which is inconvenient to use.

최근에는 신체에 상시 착용가능한 혈당 측정기가 사용되고 있으나, 이러한 혈당 측정기의 경우 적어도 3개의 바늘이 인체에 삽입되어야 하기 때문에, 사용이 불편하고 착용자의 고통이 매우 큰 문제점이 있다. In recent years, blood glucose meters that can be worn at all times have been used in the body. However, in the case of such a blood glucose meter, at least three needles must be inserted into the human body, so that the use thereof is inconvenient and the pain of the wearer is very great.

본 발명의 목적은, 사용이 간편하면서도 사용시 고통이 저감될 수 있는 레이저 가공을 통한 니들형 혈당센서 제조방법 및 니들형 혈당센서를 제공하는 데 있다. It is an object of the present invention to provide a needle type blood glucose sensor manufacturing method and a needle type blood glucose sensor through laser processing which can be easily used but suffer pain at the time of use.

본 발명에 따른 레이저 가공을 통한 니들형 혈당센서 제조방법은, 신체에 삽입되는 니들에 체액이 유입되도록 홀을 레이저를 이용해 가공하고, 상기 홀의 내주면에서 원주방향을 따라 소정각도로 이격된 위치에 서로 다른 복수의 센싱물질들이 각각 코팅된 복수의 센서층을 형성한다.A method of manufacturing a needle type blood glucose sensor by laser processing according to the present invention is characterized in that a hole is processed by a laser so that a body fluid is introduced into a needle inserted into a body and a plurality of holes are formed at positions spaced apart from each other by a predetermined angle along the circumferential direction The plurality of different sensing materials form a plurality of coated sensor layers, respectively.

본 발명에 따른 니들혈 혈당센서는, 신체에 삽입되고 체액이 유입되도록 홀이 형성된 1개의 센서용 니들과, 상기 홀의 내주면에서 원주방향을 따라 소정각도로 이격된 위치에 서로 다른 복수의 센싱물질들이 코팅되어 각각 형성되고, 상기 홀로 유입된 체액과의 접촉을 통해 혈당을 감지하는 복수의 센서층을 포함한다.The needle blood glucose sensor according to the present invention comprises a needle for a sensor which is inserted into a body and in which a hole is formed to allow a body fluid to be introduced thereinto and a plurality of sensing materials which are different from each other in a circumferential direction, And a plurality of sensor layers formed to be coated, respectively, for sensing blood glucose through contact with the bodily fluids introduced into the bodily fluids.

본 발명에 따른 니들혈 혈당센서는, 혈당을 측정하기 위한 니들이 1개만 필요하기 때문에, 사용자가 혈당센서를 착용시 신체에 니들 삽입할 때 느껴지는 고통이 저감될 수 있다. Since the needle blood glucose sensor according to the present invention requires only one needle for measuring blood glucose, the pain felt when the user inserts the needle into the body when the blood glucose sensor is worn can be reduced.

또한, 혈당 측정을 위한 니들이 1개만 삽입되기 때문에, 신체의 피부에 생기는 상처가 줄어들 수 있다.In addition, since only one needle for blood glucose measurement is inserted, wounds on the skin of the body can be reduced.

또한, 센서부에서 측정한 혈당에 따라 인슐린을 즉시 주입할 수 있기 때문에, 저혈당 쇼크 등의 위험 상황을 미리 예방할 수 있다. In addition, since insulin can be injected immediately according to the blood sugar measured by the sensor unit, a dangerous situation such as hypoglycemic shock can be prevented in advance.

도 1은 본 발명의 실시예에 따른 니들형 혈당센서를 신체에 착용한 상태가 도시된 도면이다.
도 2는 도 1에 도시된 니들혈 혈당센서의 센서용 니들이 도시된 단면도이다.
도 3은 도 2에서 A-A선 단면도이다. 1 is a view showing a state in which a needle type blood glucose sensor according to an embodiment of the present invention is worn on a body.
2 is a cross-sectional view of a needle for a sensor of the needle blood glucose sensor shown in Fig.
3 is a sectional view taken along the line AA in Fig.

이하, 첨부된 도면을 참조하여 본 발명의 실시예에 대해 상세히 설명한다.Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

도 1은 본 발명의 실시예에 따른 니들형 혈당센서를 신체에 착용한 상태가 도시된 도면이다. 도 2는 도 1에 도시된 니들혈 혈당센서의 센서용 니들이 도시된 단면도이다. 도 3은 도 2에서 A-A선 단면도이다. 1 is a view showing a state in which a needle type blood glucose sensor according to an embodiment of the present invention is worn on a body. 2 is a cross-sectional view of a needle for a sensor of the needle blood glucose sensor shown in Fig. 3 is a sectional view taken along the line A-A in Fig.

도 1을 참조하면, 본 발명의 실시예에 따른 니들형 혈당센서는 신체의 복부(2)에 각각 착용되는 혈당 센서부(10)와, 인슐린 주입부(20)를 포함한다. 상기 혈당 센서부(10)와 상기 인슐린 주입부(20)는 무선 통신에 의해 신호를 송,수신한다.Referring to FIG. 1, a needle type blood glucose sensor according to an embodiment of the present invention includes a blood glucose sensor 10 and an insulin injector 20, which are respectively worn on the abdomen 2 of the body. The blood glucose sensor unit 10 and the insulin injecting unit 20 transmit and receive signals by wireless communication.

상기 혈당 센서부(10)는, 센서용 니들(12)과 복수의 센서층(14), 송신부(16)를 포함한다. The blood glucose sensor unit 10 includes a sensor needle 12, a plurality of sensor layers 14, and a transmitter 16.

상기 센서용 니들(12)은 상기 신체의 복부(2)에 삽입되고 체액이 유입되도록 홀(12a)이 형성된다. 상기 홀(12a)은 레이저 가공에 의해 형성된다. 상기 홀(12a)은 상기 센서용 니들(12)의 길이방향을 따라 길게 형성된다. The needle 12 for the sensor is inserted into the abdomen 2 of the body and the hole 12a is formed so that body fluids can be introduced. The hole 12a is formed by laser machining. The holes 12a are elongated along the longitudinal direction of the sensor needles 12.

상기 복수의 센서층(14)은, 상기 홀(12a)의 내주면에서 원주방향을 따라 소정각도 이격된 위치에 서로 다른 복수의 센싱물질들이 코팅되어 각각 형성된다. 여기서, 상기 복수의 센서층(14)은 3개의 제1,2,3센서층(14a)(14b)(14c)로 이루어진 것으로 예를 들어 설명한다. 상기 복수의 센서층(14)의 상기 홀(12a)로 유입된 체액과의 접촉을 통해 혈당을 감지한다. The plurality of sensor layers 14 are formed by coating a plurality of different sensing materials on the inner peripheral surface of the hole 12a at positions spaced apart from each other by a predetermined angle along the circumferential direction. Here, the plurality of sensor layers 14 are composed of three first, second, and third sensor layers 14a, 14b, and 14c, for example. And detects blood sugar through contact between the plurality of sensor layers (14) and body fluids introduced into the holes (12a).

상기 송신부(16)는 상기 복수의 센서층(14)에서 감지된 신호를 무선 통신을 통해 외부로 송신한다. 여기서, 상기 송신부(16)는 후술하는 상기 인슐린 주입부(20)의 수신부(22)와 통신하는 것으로 설명한다.The transmitter 16 transmits signals sensed by the plurality of sensor layers 14 to the outside through wireless communication. Here, it is assumed that the transmitting unit 16 communicates with the receiving unit 22 of the insulin injecting unit 20 described later.

상기 인슐린 주입부(20)는, 수신부(22), 인슐린 펌프(24), 인슐린 주입용 니들(26)을 포함한다. 상기 수신부(22), 인슐린 펌프(24) 및 인슐린 주입용 니들(26)은 하나의 케이싱에 구비된다.The insulin injecting unit 20 includes a receiving unit 22, an insulin pump 24, and an insulin injecting needle 26. The receiving unit 22, the insulin pump 24, and the insulin injecting needle 26 are provided in one casing.

상기 인슐린 펌프(24)는 상기 수신부(22)에서 수신한 신호에 따라 작동된다. 상기 인슐린 펌프(24)는 인슐린이 저장되는 인슐린 저장통에 구비된다.The insulin pump 24 is operated according to a signal received by the receiving unit 22. The insulin pump 24 is provided in an insulin reservoir for storing insulin.

상기 인슐린 주입용 니들(26)은 상기 인슐린 펌프(24)에 유로로 연결되고, 상기 신체의 복부(2)에 삽입되어 상기 신체에 인슐린을 투입한다. The insulin injecting needle 26 is connected to the insulin pump 24 through a channel and inserted into the abdomen 2 of the body to inject insulin into the body.

또한, 상기 니들형 혈당센서는, 상기 복수의 센서층(14)에서 감지된 신호에 따라 상기 송신부(16)의 작동을 제어하는 제어부(미도시)를 더 포함한다. The needle-type blood glucose sensor further includes a controller (not shown) for controlling the operation of the transmitter 16 according to signals sensed by the plurality of sensor layers 14.

상기와 같이 구성된 니들형 혈당센서의 제조방법은 다음과 같다. A method of manufacturing the needle-type blood glucose sensor as described above is as follows.

먼저, 상기 센서용 니들(12)에 체액이 유입될 수 있는 홀(12a)을 레이저를 이용해 가공한다.First, the hole 12a into which the body fluid can flow into the sensor needles 12 is processed by using a laser.

이후, 상기 가공된 홀(12a)의 내주면에 원주방향을 따라 소정각도 이격된 위치에 서로 다른 복수의 센싱물질들을 각각 코팅하여 복수의 센서층(14)을 형성한다.Then, a plurality of different sensing materials are coated on the inner circumferential surface of the processed hole 12a at a predetermined angle along the circumferential direction to form a plurality of sensor layers 14.

상기와 같이 구성된 니들형 혈당센서의 작동방법을 설명하면, 다음과 같다.A method of operating the needle-type blood glucose sensor configured as described above will now be described.

사용자가 상기 혈당 센서부(10)와 상기 인슐린 주입부(20)를 각각 착용한다. 이 때, 사용자는 상기 센서용 니들(12)을 자신의 신체 복부(2)에 삽입하고, 상기 인슐린 주입용 니들(26)도 상기 복부(2)에 삽입한다. 이 때, 인슐린 주입이 필요하지 않는 환자의 경우 상기 혈당 센서부(10)만을 사용하는 것도 물론 가능하다.The user wears the blood glucose sensor part 10 and the insulin injecting part 20, respectively. At this time, the user inserts the needle for sensor 12 into his / her body part 2 and inserts the insulin injection needle 26 into the abdominal part 2 as well. At this time, it is of course possible to use only the blood glucose sensor part 10 in the case of a patient who does not need insulin injection.

상기 센서용 니들(12)이 삽입되면, 상기 센서용 니들(12)의 홀(12a)로 체액이 유입되고, 유입된 체액은 상기 복수의 센서층(14)에 접촉된다.When the needle for the sensor 12 is inserted, the body fluid flows into the hole 12a of the sensor needle 12, and the inflow body fluid comes in contact with the plurality of sensor layers 14.

상기 복수의 센서층(14)은 체액과의 접촉을 통해 혈당을 측정하게 된다. 상기 복수의 센서층(14)에서 측정된 혈당이 미리 설정된 혈당 범위를 벗어나면, 상기 송신부(16)를 통해 그에 따른 신호를 송신한다. The plurality of sensor layers 14 measure blood glucose through contact with body fluids. When the blood glucose measured in the plurality of sensor layers 14 is out of the preset blood glucose range, the signal corresponding thereto is transmitted through the transmitter 16.

상기 인슐린 주입부(20)에서는 상기 송신부(16)를 통해 송신된 신호에 따라 상기 인슐린 펌프(24)를 작동시킨다. 상기 인슐린 펌프(24)가 작동되면 상기 인슐린 주입용 니들(26)을 통해 인슐린이 적당량 주입되어, 저혈당 쇼크 등의 위험 상황이 예방될 수 있다. The insulin injector 20 operates the insulin pump 24 according to a signal transmitted through the transmitter 16. When the insulin pump 24 is operated, an appropriate amount of insulin is injected through the insulin injecting needle 26 to prevent a dangerous situation such as a hypoglycemic shock.

본 발명은 도면에 도시된 실시예를 참고로 설명되었으나 이는 예시적인 것에 불과하며, 본 기술 분야의 통상의 지식을 가진 자라면 이로부터 다양한 변형 및 균등한 다른 실시예가 가능하다는 점을 이해할 것이다. 따라서, 본 발명의 진정한 기술적 보호 범위는 첨부된 특허청구범위의 기술적 사상에 의하여 정해져야 할 것이다.While the present invention has been described with reference to exemplary embodiments, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims.

10: 혈당 센서부 12: 센서용 니들
14: 센서층 20: 인슐린 주입부
24: 인슐린 펌프 26: 인슐린 주입용 니들10: blood glucose sensor part 12: needle for sensor
14: sensor layer 20: insulin injection part
24: Insulin pump 26: Needle for insulin injection

Claims (3)

신체에 삽입되는 니들에 체액이 유입되도록 홀을 레이저를 이용해 가공하고, 상기 홀의 내주면에서 원주방향을 따라 소정각도로 이격된 위치에 서로 다른 복수의 센싱물질들이 각각 코팅된 복수의 센서층을 형성하는 레이저 가공을 통한 니들형 혈당센서 제조방법.A plurality of sensor layers coated with a plurality of different sensing materials are formed at positions spaced apart from each other by a predetermined angle in the circumferential direction on the inner circumferential surface of the hole so that the body fluid is introduced into the needle inserted into the body, A method of manufacturing a needle type blood glucose sensor by laser processing. 신체에 삽입되고 체액이 유입되도록 홀이 형성된 1개의 센서용 니들과;
상기 홀의 내주면에서 원주방향을 따라 소정각도로 이격된 위치에 서로 다른 복수의 센싱물질들이 코팅되어 각각 형성되고, 상기 홀로 유입된 체액과의 접촉을 통해 혈당을 감지하는 복수의 센서층을 포함하는 니들형 혈당센서. A sensor needle inserted into the body and having a hole for the body fluid to flow therein;
And a plurality of sensor layers formed on the inner circumferential surface of the hole at positions spaced apart from each other by a predetermined angle along a circumferential direction and formed of a plurality of different sensing materials coated on the inner circumferential surface of the hole, Blood glucose sensor. 청구항 2에 있어서,
상기 복수의 센서층에서 감지된 신호를 송신하는 송신부와;
상기 송신부에서 송신된 신호를 수신하는 수신부와;
상기 수신부의 신호에 따라 작동되는 인슐린 펌프와;
상기 인슐린 펌프에 연결되고, 상기 신체에 삽입되어 상기 신체에 인슐린을 투입하는 인슐린 주입용 니들을 더 포함하는 니들형 혈당센서.The method of claim 2,
A transmitter for transmitting a signal sensed by the plurality of sensor layers;
A receiver for receiving a signal transmitted from the transmitter;
An insulin pump operated according to a signal of the receiving unit;
And a needle connected to the insulin pump and inserted into the body for injecting insulin into the body.
KR1020140057813A 2014-05-14 2014-05-14 Needle type blood sugar sensor and the manufacturing method of the same KR20150131440A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110338888A (en) * 2019-07-18 2019-10-18 浙江荷清柔性电子技术有限公司 It is implanted into applicator

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110338888A (en) * 2019-07-18 2019-10-18 浙江荷清柔性电子技术有限公司 It is implanted into applicator
CN110338888B (en) * 2019-07-18 2024-05-07 浙江荷清柔性电子技术有限公司 Implant applicator

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