KR20080047348A - Cucurbituril added cigarettes and manufacturing method thereof - Google Patents

Abstract

A cigarette including cucurbituril, a hollow shaped nano-particle and a method for manufacturing the same are provided to reduce generation of harmful ingredients from the cigarette. A cigarette(10) including cucurbituril comprises: a cigarette rod(11) made of processed tobacco leaves; and a cigarette filter(12) including cucurbituril particles, which is combined with one side of the cigarette rod. A method for manufacturing the cigarette including cucurbituril includes the steps of: manufacturing the cigarette rod by mixing, processing, cutting, and wrapping with cigarette paper; manufacturing the cigarette filter by adding cucurbituril; and combining the cigarette rod and the cigarette filter.

Description

Tobacco with cucurbituril and its manufacturing method {CUCURBITURIL ADDED CIGARETTES AND MANUFACTURING METHOD THEREOF}

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cigarette to which cucurbituril is added and a method for manufacturing the same, and to a cigarette having a reduced amount of harmful components and a method for producing the same.

Generally, tobacco is processed according to the purpose of using tobacco leaf as a raw material. These cigarettes can be divided into cigarettes (cigarette), cigars, cigars and the like as most of them for smoking. Cigarettes make up the majority of cigarettes, and cigarettes are often referred to as cigarettes.

Tobacco contains a large amount of harmful ingredients, so excessive smoking can have serious consequences for human health. Therefore, in recent years, there has been a regulation to prohibit smoking in public places, and the degree of the regulation is gradually strengthening.

The research on the association between smoking and disease has been intensively studied since the mid-1900s, and there is a continuous accumulation of evidence for the increase in the incidence of various diseases including lung cancer and other health problems due to smoking. In fact, about 4,000 kinds of components have been found in cigarette smoke so far, and these components account for about 95% of the total volume of tobacco smoke, and the remaining thousands of components are present in extremely small amounts.

Tobacco smoke is caused by incomplete combustion of tobacco, and when tobacco is completely burned, only water and carbon dioxide are generated. This incomplete combustion is caused by incomplete combustibility of some tobacco leaf components, insufficient oxygen supply and local temperature differences when the cigarette is burned.

In addition, the combustion process is a process of distillation, sublimation, pyrolysis, thermal synthesis, volatilization. Tobacco smoke is an aerosol that is a mixture of liquid or fine particles in a gas.A Cambridge glass fiber filter has the efficiency of filtering 99% or more of particles larger than 0.1 μm in diameter. The material that passed through) is called a gas or vapor component, and these components consist of nitrogen (59%), oxygen (13.4%), carbon dioxide (13.5%), carbon monoxide (3.2%), In addition, it contains volatile components having low molecular weight such as aldehydes, ketones, alcohols, and esters, which are toxic to bronchial cilia.

The material filtered by the Cambridge glass fiber filter is called particulates phasecomponents, which make up about 8% of tobacco smoke. Such particulate matter includes at least 38 known carcinogens, including tar, and potentially carcinogens, nicotine, many kinds of inorganic and organic chemicals.

Republic of Korea Patent Application Publication No. 2005-0083035, 1999-0031164 attached to the filter containing activated carbon, zeolite particles, adsorbent powder, etc. to minimize the amount of harmful components in the human body inhaled in the smoke when smoking Tobacco is disclosed.

However, these methods are not satisfactory enough to reduce the amount of harmful components inhaled in the body when smoking.

Technical challenge

Accordingly, it is an object of the present invention to provide a tobacco and a method for producing the same in which the amount of harmful components is reduced.

Technical solution

According to the invention,

Tobacco filter comprising a cucurbituril of formula (1) is provided.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

According to one embodiment of the invention, X is O, A ₁ and A ₂ are both H and n is an integer from 5 to 12.

According to another embodiment of the present invention, X is O, A ₁ and A ₂ are both OH, and n is an integer of 5 to 12.

According to another embodiment of the present invention, X is O, A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12.

Also according to the invention,

Tobacco rod formed by rolling the processed leaf tobacco with citrus paper; And

To provide a cigarette comprising a cucurbituril of formula (1) and having a tobacco filter coupled to one side of the tobacco rod to filter out harmful components.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

Also according to the invention,

Tobacco rod formed by rolling the processed leaf tobacco with citrus paper; And

Is coupled to one side of the tobacco rod is provided with a tobacco filter for filtering harmful components,

There is provided a cigarette comprising a cucurbituril of Formula 1 between the tobacco rod and the tobacco filter.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

Also according to the invention,

Mixing, processing, and cutting the leaf tobacco, and then rolling the tobacco paper to produce a tobacco rod;

To prepare a tobacco filter by adding the cucurbituril of the formula (1); And

Combining the tobacco rod and a tobacco filter; there is provided a tobacco manufacturing method comprising a.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

Also according to the invention,

Mixing, processing, and cutting the leaf tobacco, and then rolling the tobacco paper to produce a tobacco rod;

Preparing a tobacco filter;

Preparing a cucurbituril of Formula 1; And combining the tobacco rod, the tobacco filter, and the cucurbituril.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a flow chart illustrating a manufacturing process of the tobacco added cucurbituril according to an embodiment of the present invention.

Referring to Figure 1 will be described in detail with respect to the manufacturing process of the tobacco to which the cucurbituril is added.

First, various leaf tobacco is mixed (S10). The mixing of leaf tobacco is a process for producing unique tobacco using the unique aroma, taste, or color of various tobacco leaves. Through this process, tobacco has its own taste and aroma.

Next, the mixed raw material is processed (S12). The processing of raw materials is to enhance the merchandise of tobacco by going through the process of fermentation, heating, flavoring, removal of defective parts. It is also possible to soften the leaf tobacco through humidification or heating.

Next, the processed tobacco leaves are cut to an appropriate size (S14). The cut leaf tobacco mixture is conveyed to a tobacco maker (not shown).

Thereafter, the tobacco maker rolls the transported tobacco leaf mixture with cigarette paper to make a tobacco rod without a filter (S16).

On the other hand, the cigarette filter is manufactured in a separate process (S30). In this case, cucurbituril may be added to the cigarette filter (S40). The content of cooker bituril is preferably 1 part by weight to 99 parts by weight, and more preferably 25 parts by weight to 75 parts by weight based on 100 parts by weight of the tobacco filter. If the content of the cucurbituril is less than 1 part by weight with respect to 100 parts by weight of the tobacco filter, the removal efficiency of harmful components by the cucurbituril is not preferable.

Next, the tobacco rod and the tobacco filter are combined (S18). In this case, the cucurbituril may be included between the tobacco rod and the tobacco filter without adding the cucurbituril to the cigarette filter (S40).

Finally, the individual cigarettes thus prepared are packaged (S20) to finally complete the product.

Cookerbituril was first reported in 1905 by R. Behrend, E. Meyer and F. Rusche. In 2000, Kim Ki-moon and his co-workers improved the method of synthesizing conventional cucurbituril [6], synthesizing and separating not only cucurbituril [6] but also the homologue cucurbituril [n] (n = 5, 7, 8). The structure was confirmed by X-ray diffraction (J. Am. Chem. Soc. 2000, 122, 540).

The cooker bituril will be described later.

Figure 2 is a perspective view of a cigarette added to cucurbituril according to an embodiment of the present invention.

2, a cigarette 10 according to an embodiment of the present invention includes a cigarette rod 11 and a cigarette filter 12.

The tobacco rod 11 is formed by rolling the tobacco leaf mixture into cigarette paper as described above.

The cigarette filter 12 includes a first filter part 12a in contact with the cigarette rod 11, a third filter part 12c in contact with a smoker's mouth, and a first filter part 12a and a third filter part 12c. The second filter unit 12b is disposed between.

The first filter part 12a and the third filter part 12c are conventional fiber filters, and the filter parts 12a and 12c may be formed of the same material or different materials.

The second filter part 12b includes a cooker bituril represented by Chemical Formula 1 below.

[Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20.

Specifically, X is O, A ₁ and A ₂ are both H, and n is preferably an integer of 5 to 12.

Also specifically, X is O, A ₁ and A ₂ are both OH, and n may be an integer of 5 to 12.

Also specifically, X is O, A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n may be an integer of 5 to 12.

The above cucurbituril and cucurbituryl derivatives are compounds composed of glycoryl monomers without substituents. On the other hand, there is also disclosed a cucurbituril derivative synthesized using a glycoryl with a substituent introduced (Angew. Chem. Int. Ed, Engl. 1992, 31, 1475). Hereinafter, the cucurbituril and the cucurbituryl derivatives will be collectively referred to simply as cucurbituril.

Cookerbituril is a macrocyclic molecular compound, which has a lipophilic pupil, and has a hydrophilic inlet on both sides. Therefore, such cucurbituril has a lipophilic interaction in the cavity, and hydrogen bonds, polar interactions, cation-polar interactions, etc., at the two upper and lower entrances where six carbonyl groups are located, respectively, and are very different from various kinds of compounds. It shows the inclusion effect through stable non-covalent bond. In particular, such cucurbituril forms a complex through a non-covalent bond that is very stable against compounds having functional groups such as alkyl chains, amino groups, carboxylic acids, and alkali metals, heavy metals, amine groups, etc. Can be applied to

Meanwhile, the cucurbituril is a host molecule having an empty space therein and is known to form a master-guest molecular compound through a non-covalent bond (Acc. Chem. Res. 2003, 36, 621). Therefore, it has various molecules capable of forming a complex through covalent non-coupling with the cucurbituril and adsorption ability to harmful gases such as CO and NOx ( Angew. Chem. Int. Ed. 2002 , 41 , 3020.,) can filter out specific molecules or gases. Therefore, when the aforementioned cucurbituril homologues and derivatives or mixtures thereof are added to existing tobacco filters, filtration, deodorization of toxic substances such as nicotine, tar, nicotelin, anabacin and CO, NO, NOx, etc. by smoking, Inhalation of the body can be minimized by improving neutralization and removal ability.

Hydroxy cucurbituril represented by Formula 1 and having an alcohol group having an active substituent introduced into cucurbituril was developed after the research team continuously studied cucurbituril as a drug carrier (Korean Patent Publication No. 2003-60053). Such hydroxy cucurbituril facilitates the introduction of various functional groups and thus enables the synthesis of various kinds of cucurbituril derivatives.

In addition, the second filter part 12b may include only one cooker bituril of the cooker bituril represented by Formula 1, or may include two or more cooker biturils.

Hereinafter, cucurbituril corresponding to the value of n in Formulas 1 and 2 will be referred to as cucurbituril [n], respectively.

2 shows that the second filter part 12b including the cucurbituril is disposed separately from the first and third filter parts 12a and 12c, but the present invention is not limited thereto. 12b and the first and third filter parts 12a and 12c may be integrally formed. That is, in this case, the cooker bituril is dispersed and added to the first and third filter parts 12a and 12c.

Figure 3 is a perspective view of a tobacco added cucurbituril added according to another embodiment of the present invention.

The cigarette 20 according to the present embodiment includes a tobacco rod 21, a cigarette filter 22, and a cooker bituril 23.

This embodiment differs from the embodiment of FIG. 2 in that the cucurbituril 23 is not included in the tobacco filter 22 but is disposed between the tobacco rod 21 and the tobacco filter 22.

In the embodiment of Figures 2 and 3 such structural differences lead to differences in the manufacturing process. That is, in the case of Figure 2, the tobacco manufacturing process includes a tobacco rod manufacturing process-cigarette filter manufacturing process-a tobacco rod and a cigarette filter combined process, in the case of Figure 3 tobacco manufacturing process tobacco rod manufacturing process-tobacco filter Manufacturing process—tobacco rod, tobacco filter, and cucurbituril bonding process. That is, the cucurbituril is included in the cigarette filter 12 through the cigarette filter manufacturing process in FIG. 2, but in the case of FIG. It is included in the cigarette 20 through the process.

Favorable effect

According to the present invention, it is possible to provide a cigarette and a method of manufacturing the same in which the amount of harmful components is reduced.

Best Mode for Carrying Out the Invention

Hereinafter, examples of the present invention are specifically illustrated, but the present invention is not limited to the following examples.

1 is a flow chart illustrating a manufacturing process of the tobacco added cucurbituril according to an embodiment of the present invention.

Figure 2 is a perspective view of a cigarette added to cucurbituril according to an embodiment of the present invention.

Figure 3 is a perspective view of a cigarette added to cucurbituril according to another embodiment of the present invention.

(Example 1)

Tobacco manufacturing

100 mg of cucurbituril [5] in powder form was finely ground and placed in a conventional tobacco (THIS ™, KT & G ™) filter as shown in FIG. 2 to prepare a test cigarette. Wherein X is O, A ₁ and A ₂ are all H;

Determination of Nicotine Concentration in Cigarette Filters

The test tobacco was inserted into a tobacco pipe to smoke, and then the tobacco filter was separated to determine the content of nicotine components adsorbed on the tobacco filter as follows. That is, the separated tobacco filter was eluted with about 15 ml of ethyl acetate, and then distilled under reduced pressure, 100 µl of ethyl acetate was dissolved in the residue, and used as an analytical sample. The analysis was performed using gas chromatography (HP, 5890. FID attached, USA), and the column was filled with 2% Tharmon 1000 + 1% KOH chromosorb WAM (8 / 100mesh), 3 mm in diameter and 2 m in length. Column was used. The column temperature was 100 ° C., the carrier gas was nitrogen, and the flow rate was 60 ml / min.

The results of measuring nicotine concentration are shown in Table 1 below.

TABLE 1

A: Use only existing cigarette filters without adding cucurbituril

B: I use the cigarette filter containing 100 mg of cucurbituril

In Table 1, it can be seen that a large amount of nicotine remains in the tobacco filter when the tobacco filter including the cucurbituril was used. Therefore, it can be seen through these results that the effect of reducing the amount of nicotine released to the outside of the tobacco filter cigarette filter.

Determination of CO and NO gas volume in the gas exiting the tobacco filter

Tobacco smoke exiting the cigarette filter was collected and the amount of CO and NO was measured. Analysis was performed using a gas analyzer (Eurotron, UniGas 3000+, Italy).

The results of measuring the amount of CO and NO gas are shown in Table 2 below.

TABLE 2

A: Use only existing cigarette filters without adding cucurbituril

B: Use the tobacco filter containing 100 mg of cucurbituril

From Table 2, it can be seen that the effect of reducing the amount of CO and NO gas emitted to the outside of the cigarette filter cigarette.

(Example 2)

Tobacco manufacturing

Test cigarettes were prepared in the same manner as in Example 1, except that cucurbituril [7] was used instead of cucurbituril [5].

Determination of Nicotine Concentration in Cigarette Filters

In the same manner as in Example 1, the concentration of nicotine adsorbed in the tobacco filter was measured.

The results of measuring nicotine concentration are shown in Table 3 below.

TABLE 3

A: Use only existing cigarette filters without adding cucurbituril

B: I use the cigarette filter containing 100 mg of cucurbituril

From Table 3, it can be seen that a large amount of nicotine remains in the tobacco filter when the tobacco filter including the cucurbituril was used. Therefore, it can be seen through these results that the effect of reducing the amount of nicotine released to the outside of the tobacco filter cigarette filter.

Determination of CO and NO gas volume in the gas exiting the tobacco filter

In the same manner as in Example 1, the amount of CO and NO was measured by collecting tobacco smoke exiting the tobacco filter.

The results of measuring the amount of CO and NO gas are shown in Table 4 below.

TABLE 4

A: Use only existing cigarette filters without adding cucurbituril

B: Use the tobacco filter containing 100 mg of cucurbituril

It can be seen from Table 4 that the effect of reducing the amount of CO and NO gas emitted to the cucurbituril outside the cigarette filter.

(Example 3)

Tobacco manufacturing

Except for using Cucurbituril [5] of Formula 1 above, except that Cucurbituril [5], [6], [7], and [8] were mixed in a weight ratio of 1: 1: 1: 1, respectively. A test cigarette was prepared in the same manner as in 1.

Determination of Nicotine Concentration in Cigarette Filters

In the same manner as in Example 1, the concentration of nicotine adsorbed in the tobacco filter was measured.

The results of measuring nicotine concentration are shown in Table 5 below.

TABLE 5

A: Use only existing cigarette filters without adding cucurbituril

B: I use the cigarette filter containing 100 mg of cucurbituril

From Table 5, it can be seen that a large amount of nicotine remains in the tobacco filter when the tobacco filter including the cucurbituril was used. Therefore, it can be seen through these results that the effect of reducing the amount of nicotine released to the outside of the tobacco filter cigarette filter.

Determination of CO and NO gas volume in the gas exiting the tobacco filter

In the same manner as in Example 1, the cigarette smoke exiting the cigarette filter was collected and the amount of CO and NO was measured.

The results of measuring the amount of CO and NO gas are shown in Table 6 below.

TABLE 6

A: Use only existing cigarette filters without adding cucurbituril

B: Use the tobacco filter containing 100 mg of cucurbituril

It can be seen from Table 6 that the effect of reducing the amount of CO and NO gas emitted to the outside of the cigarette filter cigarette filter.

(Example 4)

Tobacco manufacturing

X is O, A, except that ₁ and A ₂ are both the place of cucurbituril [5] of the above formula 1 H and X is O, A ₁ and A ₂ are both used a cucurbituril [6] of the above formula 1 OH And to prepare a test cigarette in the same manner as in Example 1.

Determination of Nicotine Concentration in Cigarette Filters

In the same manner as in Example 1, the concentration of nicotine adsorbed in the tobacco filter was measured.

The results of measuring nicotine concentration are shown in Table 7 below.

TABLE 7

A: Use only existing cigarette filters without adding cucurbituril

B: I use the cigarette filter containing 100 mg of cucurbituril

From Table 7, it can be seen that a large amount of nicotine remains in the cigarette filter when the cigarette filter including the cucurbituril is used. Therefore, it can be seen through these results that the effect of reducing the amount of nicotine released to the outside of the tobacco filter cigarette filter.

Determination of CO and NO gas volume in the gas exiting the tobacco filter

In the same manner as in Example 1, the amount of CO and NO was measured by collecting tobacco smoke exiting the tobacco filter.

The results of measuring the amount of CO and NO gas are shown in Table 8 below.

TABLE 8

A: Use only existing cigarette filters without adding cucurbituril

B: Use the tobacco filter containing 100 mg of cucurbituril

It can be seen from Table 8 that the effect of reducing the amount of CO and NO gas emitted to the outside of the cigarette filter cigarette filter.

In the present embodiment, when cooker bituril is added to tobacco, only the filtering effect on nicotine, and CO and NO gas among the harmful components of the cigarette has been examined. Inhalation of harmful components by smoking can be minimized by improving the ability to filter, deodorize, neutralize, or remove harmful components such as the like.

Although the preferred embodiment according to the present invention has been described above, this is merely exemplary, and it will be understood by those skilled in the art that various modifications and equivalent other embodiments are possible. Therefore, the protection scope of the present invention should be defined by the appended claims.

Claims (20)

Tobacco filter comprising a cucurbituril of formula (1). [Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted hwandoen C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20. The method of claim 1, X is O, and A ₁ and A ₂ are both H and n is an integer of 5 to 12, wherein the tobacco filter. The method of claim 1, X is O, and A ₁ and A ₂ are both OH, and n is an integer of 5 to 12, wherein the tobacco filter. The method of claim 1, X is O, and A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12, wherein the tobacco filter. Tobacco rod formed by rolling the processed leaf tobacco with citrus paper; And Tobacco comprising a cucurbituril of formula (1) and having a tobacco filter coupled to one side of the tobacco rod to filter out harmful components. [Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20. The method of claim 5, Wherein X is O, and A ₁ and A ₂ are both H and n is an integer of 5 to 12. The method of claim 5, X is O, A ₁ and A ₂ are both OH, and n is an integer of 5 to 12, characterized in that tobacco. The method of claim 5, Wherein X is O, and A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12. Tobacco rod formed by rolling the processed leaf tobacco with citrus paper; And Is coupled to one side of the tobacco rod is provided with a tobacco filter for filtering harmful components, Tobacco comprising a cucurbituril of formula (1) between the tobacco rod and the tobacco filter. [Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20. The method of claim 9, Wherein X is O, and A ₁ and A ₂ are both H and n is an integer of 5 to 12. The method of claim 9, X is O, A ₁ and A ₂ are both OH, and n is an integer of 5 to 12, characterized in that tobacco. The method of claim 9, X is O, and A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12, wherein the tobacco filter. Mixing, processing, and cutting the leaf tobacco, and then rolling the tobacco paper to produce a tobacco rod; Preparing a tobacco filter by adding cucurbituril of Formula 1; And combining the tobacco rod and the tobacco filter. [Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20. The method of claim 13, Wherein X is O, A ₁ and A ₂ are both H, and n is an integer of 5 to 12. The method of claim 13, Wherein X is O, A ₁ and A ₂ are both OH, and n is an integer of 5 to 12. The method of claim 13, X is O, and A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12. Mixing, processing, and cutting the leaf tobacco, and then rolling the tobacco paper to produce a tobacco rod; Preparing a tobacco filter; Preparing a cucurbituril of Formula 1; And Combining the tobacco rod, tobacco filter, and cucurbituril; tobacco production method comprising a. [Formula 1]

Wherein X is O, S or NH; and A ₁ and A ₂ are each H, OR ¹ , OR ² or SR ¹ , SR ² or NHR ¹ , NHR ² ; R ¹ and R ² are each independently hydrogen, substituted or unsubstituted C ₁ -C ₃₀ alkyl, substituted or unsubstituted C ₁ -C ₃₀ alkenyl, substituted or unsubstituted C ₁ -C ₃₀ alkynyl , Substituted or unsubstituted C ₂ -C ₃₀ carbonylalkyl, substituted or unsubstituted C ₁ -C ₃₀ thioalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylthiol, substituted or unsubstituted C ₁ -C ₃₀ Alkoxy, substituted or unsubstituted C ₁ -C ₃₀ hydroxyalkyl, substituted or unsubstituted C ₁ -C ₃₀ alkylsilyl, substituted or unsubstituted C ₁ -C ₃₀ aminoalkyl, substituted or unsubstituted C _1- C ₃₀ aminoalkylthioalkyl, substituted or unsubstituted C ₅ -C ₃₀ cycloalkyl, substituted or unsubstituted C ₂ -C ₃₀ heterocycloalkyl, substituted or unsubstituted C ₆ -C ₃₀ aryl, substituted or unsubstituted hwandoen C ₆ -C ₂₀ aryl, substituted or unsubstituted C ₄ -C ₃₀ heteroaryl group, and a heteroaryl group consisting of alkyl substituted or unsubstituted C ₄ -C ₂₀ from Selected at least one; and, n is an integer of 4 to 20. The method of claim 17, Wherein X is O, A ₁ and A ₂ are both H, and n is an integer of 5 to 12. The method of claim 17, Wherein X is O, A ₁ and A ₂ are both OH, and n is an integer of 5 to 12. The method of claim 17, X is O, and A ₁ and A ₂ are both O—CH ₂ —CH═CH ₂ , and n is an integer of 5 to 12, wherein the tobacco filter.

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