KR102155354B1 - Mobile Multisensing Implant And Monitoring System For High-Risk Senile Disease Having The Same - Google Patents

Abstract

A wireless multi-sensing implant and a high-risk elderly disease constant monitoring system including the same are presented. An implant according to an embodiment of the present invention is an implant that is placed in the oral cavity of the human body, and has a hollow structure in which a thread is formed on an outer circumferential surface to be placed in the oral cavity of the human body, and a thread is formed on the inner circumferential surface so that the processor unit part can be bolted to the inside. , A sensor unit unit in which a first sensor is mounted in a form surrounding a thread formed on an outer circumferential surface; And a bolt structure having a screw thread formed on an outer surface so as to be bolted to the sensor unit part, a communication antenna is mounted in a form surrounding the thread formed on the outer circumferential surface, a second sensor is mounted on the outer surface, and the first sensor and the second The summary of the configuration is to include; a processor unit unit with an integrated IC chip that stores data detected from the sensor and transmits the stored data to the outside.
According to the present invention, it is possible to detect the blood-like and non-blood-based multiple biomarkers of a target patient in real time, and it is possible to easily determine the status of the target patient based on the detected data, thereby remarkably improving the accessibility of the elderly patient. In addition, it is possible to solve the problems of a medical management system according to the prior art in which the accessibility of elderly patients is very weak, and to provide an effective and rapid health care management system for high-risk elderly diseases.

Description

Mobile Multisensing Implant And Monitoring System For High-Risk Senile Disease Having The Same}

The present invention relates to a wireless multi-sensing implant and a high-risk elderly disease monitoring system including the same, and in more detail, a wireless multi-sensing implant configured to monitor high-risk elderly diseases such as diabetes, peri-implantitis and Alzheimer's disease, and the same. It relates to a technology for establishing an active medical treatment system for relevant diseases with a constant monitoring system for high-risk elderly diseases.

With the recent development of medicine, life expectancy is prolonged, and the elderly population rapidly increases, and there is an increasing demand for a response and management plan for diseases that threaten the healthy life of the elderly.

Diabetes, peri-implantitis, and Alzheimer's disease, which are commonly referred to as the top three high-risk elderly diseases, are serious obstacles to maintaining a healthy life in the elderly, and enormous national costs are required to manage and respond to these diseases. As a medical system, there are many limitations in the efficient management of this.

Under the conventional medical management system, access to the elderly patient is very weak, so unless the elderly patient with high-risk disease and mobility difficulties directly visit the hospital and receive medical examination, under the existing medical management system, the disease deterioration of the elderly patient is prevented. It is impossible to recognize or respond.

Specifically, in the case of diabetic patients, they must intermittently measure their blood sugar with a blood glucose meter (BG meter), which is a standard blood glucose monitoring machine.Therefore, it is quite inconvenient to use patients with disabilities in behavior such as the elderly. There is a problem in that it is not possible to respond at all to hypoglycemic emergencies that may occur during nighttime bedtime.

In addition, as the number of cases of dental implant surgery is increasing, the incidence of peri-implantitis is also increasing. Due to the nature of peri-implantitis that occurs after a certain period of time after dental implant surgery, the disease is very likely to develop in the elderly. .

Peri-implantitis is a new disease that is completely different from normal periodontal disease in terms of mechanism and structure, and standardized guidelines for treatment have not yet been established, and since the spread of inflammation is very fast, it is used for constant monitoring. Early detection of the disease has a decisive effect on the prognosis of the disease, so a quick diagnosis of peri-implantitis is essential.

In the case of Alzheimer's disease (dementia), which is the most representative and fatal disease in the elderly, it is very important to use a location tracking device when managing patients due to worsening symptoms, and systematic management by monitoring the symptom trend of patients with Alzheimer's history is required. The need is increasing.

If a close examination is required according to the types of these senile diseases, the target patient should visit the hospital regularly, dedicating time.

In general, in order to examine senile diseases, it is necessary to detect a large amount of information about a target patient, that is, a biomarker, and a detailed examination in which this detection process is performed takes a lot of time.

If the subject patient's senile disease rapidly worsens If the elderly patient is exposed to other risk situations due to weakened physical function, it becomes impossible for the target patient to visit the hospital directly. Therefore, in order to solve such a problem, a method of monitoring the physical condition of the target patient in real time should be reviewed.

For example, as shown in FIG. 1, a patient monitoring device having a collection liquid collector, an infusion regulator, a bodily fluid collector condition meter, and a body may be considered.

Specifically, in the case of the monitoring device shown in FIG. 1, a catheter is inserted into a target patient and desired data is detected through a urine bag connected to the catheter to determine the state of the target patient.

However, the device according to the prior art shown in FIG. 1 is a configuration that cannot be easily attached to or removed from a target patient, and a problem in that it causes very great inconvenience to the daily life of the target patient due to the collection liquid collector 1 such as a urine bag. There is.

Therefore, there is an urgent need to develop a technology capable of solving the problems of the prior art.

Korean Patent Registration No. 10-1576900 (registered on December 07, 2015)

An object of the present invention is to provide a wireless multi-sensing implant to enable constant monitoring in order to solve the problem of a medical management system according to the prior art, in which the accessibility of elderly patients is very weak, and to provide a high-risk elderly disease including such an implant. By establishing a monitoring system, it is to provide an effective and rapid health care management system for high-risk senile diseases.

The implant according to one aspect of the present invention for achieving this purpose is an implant that is placed in the oral cavity of the human body, and has a thread formed on the outer circumferential surface so that it is placed in the oral cavity of the human body, and the processor unit is bolted to the inner circumferential surface so that it can be fastened. A sensor unit unit having a hollow structure having a thread formed therein and in which the first sensor is mounted in a form surrounding the thread formed on the outer circumferential surface; And a bolt structure having a screw thread formed on an outer surface so as to be bolted to the sensor unit part, a communication antenna is mounted in a form surrounding the thread formed on the outer circumferential surface, a second sensor is mounted on the outer surface, and the first sensor and the second It may be a configuration including a; a processor unit unit with an integrated IC chip that stores the data detected from the sensor and transmits the stored data to the outside.

In one embodiment of the present invention, the sensor unit may be an artificial tooth root (fixture) structure that is placed in the upper or lower jaw in the oral cavity of the human body.

In this case, the processor unit may be bolted to the sensor unit and may have an abutment structure capable of mounting an artificial tooth on the upper part.

In one embodiment of the present invention, the integrated IC chip may have a configuration including a data storage unit that stores data detected from the first sensor and the second sensor.

In addition, the processor unit may have a configuration including a wireless communication device for transmitting data stored in the integrated IC chip to the outside.

In one embodiment of the present invention, a battery capable of charging and discharging, a self-powered device, or an RF-based energy generating device may be mounted inside or on one side of the processor unit.

In this case, the self-powered device includes: a piezoelectric element mounted adjacent to the upper surface of the processor unit unit and receiving a pressing force from an intraoral mastication motion to generate electric power; And a condenser mounted inside the processor unit and storing power generated from the piezoelectric element.

In addition, the RF-based energy generating device may include an induction coil having a loop structure surrounding an outer peripheral surface of the processor unit unit; And a capacitor mounted inside the processor unit and storing power generated from the induction coil.

In an embodiment of the present invention, the first sensor mounted on the outer circumferential surface of the sensor unit may be a blood sensor that detects a blood biomarker.

In addition, the second sensor mounted on the outer peripheral surface of the processor unit may be a sensor that detects a non-blood biomarker from gingival fissure or saliva.

In this case, the second sensor may be mounted on a portion adjacent to the gingival fissure formed on the interface between the artificial tooth and the gum.

The present invention can also provide a high-risk elderly disease constant monitoring system including the implant bar, the high-risk elderly disease constant monitoring system according to an aspect of the present invention, after receiving data from the processor unit of the implant, delivery An information extracting unit that determines a state of the human body based on the obtained data and stores result data; And an information transmission unit that determines whether there is an emergency situation based on the result data obtained through the information extraction unit, and transmits the emergency situation and the patient's location information to the emergency room or hospital in case of an emergency.

In an embodiment of the present invention, the processor unit of the implant may repeatedly detect data from the first sensor and the second sensor during a preset time interval and then store the detected data by time.

As described above, according to the implant of the present invention, by providing a sensor unit unit and a processor unit unit having a specific structure, it is possible to detect blood and non-blood multi-biomarkers of a target patient in real time, and the detected data is Based on this, it is possible to easily judge the condition of the target patient, which can significantly improve the accessibility of elderly patients.

In addition, according to the implant of the present invention, by providing a processor unit unit having a structure that can be easily inserted or removed in the oral cavity of the human body, it is possible to provide an implant of a customized structure by easily reflecting the intraoral structure of the target patient. The maintenance of the processor unit is easy.

In addition, according to the implant of the present invention, by providing a battery of a specific structure, a self-powered device, or an RF-based energy generating device, a configuration for power supply can be compactly configured, so that the overall structure of the implant can be miniaturized, Since the implant can be driven in real time without a separate power supply, real-time monitoring of the target patient can be implemented.

In addition, according to the implant of the present invention, it is possible to utilize the advantages of a dental treatment system that is very accessible, and can actively control the operation of the sensor unit and data collection in both directions, and it is possible to perform repetitive measurements to implement efficient management of high-risk diseases. have.

In addition, according to the high-risk elderly disease constant monitoring system of the present invention, by providing an implant that performs a specific role, an information extraction unit, and an information transmission unit, it solves the problems of the medical management system according to the prior art that the accessibility of the elderly patient is very weak. In addition, it can provide an effective and rapid health care management system for high-risk senile diseases.

In addition, according to the constant monitoring system for high-risk elderly diseases of the present invention, it is possible to implement an innovative health care system by targeting three representative high-risk elderly diseases, and by using multiple sources such as blood biomarkers and non-blood biomarkers. Personalized precise diagnosis is possible, and by using an implant that includes a configuration capable of two-way wireless operation, it can effectively cope with emergency situations, and maximize accessibility and convenience by utilizing the clinical and industrial advantages of dental units and dental implants. .

1 is a block diagram showing a patient monitoring device according to the prior art.
Figure 2 is an exploded assembly view showing an implant according to an embodiment of the present invention.
FIG. 3 is a plan view looking down from the upper surface by extracting only the processor unit of FIG. 2.
4 is a schematic diagram showing a state in which an implant is placed in an oral cavity according to an embodiment of the present invention.
5 is a partially enlarged view showing a state in which an implant is placed in an oral cavity according to an embodiment of the present invention.
6 is a block diagram showing a system for constantly monitoring high-risk elderly diseases according to an embodiment of the present invention.
7 is a schematic diagram showing a state of operating a system for monitoring at risk elderly diseases according to an embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the drawings. Prior to this, terms or words used in the specification and claims should not be construed as being limited to a conventional or dictionary meaning, but should be interpreted as meanings and concepts consistent with the technical idea of the present invention.

Throughout this specification, when a member is said to be positioned "on" another member, this includes not only the case where the member is in contact with the other member, but also the case where another member exists between the two members. Throughout this specification, when a certain part "includes" a certain component, it means that other components may be further included rather than excluding other components unless otherwise stated.

FIG. 2 is an exploded and assembled view showing an implant according to an embodiment of the present invention, and FIG. 3 is a plan view viewed downward from an upper surface by extracting only the processor unit of FIG. 2.

Referring to these drawings, the implant 100 according to the present embodiment is to be placed in the oral cavity of the human body, and in particular, it may be placed at a point having excellent accessibility, such as inside the normal dentition, the posterior of the posterior tooth, or the palate of the palate.

The implant 100 according to the present embodiment may be configured to include a sensor unit unit 110 and a processor unit unit 120 having a specific structure, as shown in FIGS. 2 and 3.

Specifically, the sensor unit unit 110 has a structure in which threads are formed on the outer circumferential surface to be inserted into the oral cavity of the human body, and may have a hollow structure in which threads are formed on the inner circumferential surface so that the processor unit unit 120 can be bolted to the inside. When the sensor unit unit 110 is implanted in the alveolar bone of the maxilla or mandible in the oral cavity, the structure of the sensor unit unit 110 may be an artificial jigsaw (fixture) structure of a dental implant.

The first sensor 111 may be mounted on a thread formed on the outer peripheral surface of the sensor unit 110 in a form surrounding the outer peripheral surface.

At this time, the first sensor 111 is a blood sensor, and may detect a blood biomarker by being placed in the oral cavity. Specifically, when the sensor unit unit 110 is placed in the alveolar bone, a blood biomarker may be detected from blood flowing along the alveolar bone.

The first sensor 111 may detect glucose contained in blood, and through this, may obtain data on diabetes of a target patient. In addition, it is possible to determine whether peri-implantitis by measuring the acidity (pH) of blood detected around the alveolar bone, that is, around the teeth.

The first sensor 111 may be connected to the integrated IC chip 122 embedded in the processor unit unit 120 through the data transmission line 112 formed on the outer circumferential surface or inside the sensor unit unit 110. In this case, the data transmission line 112 may be a energized cable or a circuit printed on the outer surface of the sensor unit unit 110. When the data transmission line 112 is a printed circuit, it is preferable that the surface exposed to the outside is coated with an insulating material.

The sensor unit unit 110 having a structure including the first sensor 111 and the data transmission line 112 may be manufactured by a method such as insert injection molding or extrusion molding, and the intention of the designer and the condition of the target patient Of course, it is possible to select appropriate changes according to the requirements.

The processor unit unit 120 according to the present embodiment may be bolted to the sensor unit unit 110 and may have a bolt structure having a thread formed on an outer surface thereof.

When the above-mentioned sensor unit unit 110 is placed in the alveolar bone of the maxilla or mandible in the oral cavity, the processor unit unit 120 is bolted to the sensor unit unit 110, and the artificial tooth 101 is mounted thereon. It may be an abutment structure.

In this case, as shown in FIG. 2, a communication antenna 123 may be mounted on the outer surface of the processor unit 120 in a thread-wrapped form. In this case, the communication antenna 123 may be connected to the integrated IC chip mounted inside the processor unit 120 to transmit data stored in the integrated IC chip 122 to the outside.

In addition, the second sensor 121 may be mounted on the outer surface of the processor unit unit 120. At this time, the second sensor 121 is configured to detect a non-blood biomarker from gingival fissure and saliva.

The second sensor 121 is a sensor that utilizes saliva or gingival fissure fluid, and may be composed of two sensors, as shown in FIGS. 2 and 3.

One of the second sensors 121 is a sensor that detects data from a crevicular fluid. The gingival fissure fluid (crevicular fluid) is the first body fluid secreted from the inside of the body in the gingival fissure, and is a sample that most accurately reflects changes in body conditions. As shown in FIG. 5, the gingival fissure is a name that refers to a small gap formed at the interface between a tooth and a gum, and generally has a depth of about 3 mm. Numerous bacteria breed in the gingival fissure and attack the gingival, alveolar bone (gingival bone), and periodontal ligaments that support the teeth. The exudate from the epithelium of the gingival fissure is gingival fissure fluid (crevicular fluid), and it plays a role in protecting the gums from these bacteria.

In addition, the other of the second sensors 121 may detect saliva in the oral cavity to detect the Alzheimer's biomarker. Specifically, the Alzheimer's biomarker can be detected in the tear protein. At this time, since the fistula and the oral cavity share an anatomical space, the Alzheimer's biomarker can be detected from saliva remaining in the oral cavity.

The integrated IC chip 122 mounted inside the processor unit unit 120 according to the present embodiment may store data acquired from the first sensor 121 and the second sensor 122 therein. In this case, it is preferable that the integrated IC chip 122 has a structure including a data magnetic field (not shown) therein. The integrated IC chip 122 including the data storage unit can be easily separated together with the processor unit unit 120. Therefore, it is possible to easily identify the state of the target patient based on data stored in the integrated IC chip 122 of the processor unit 120 by visiting a dental hospital or the like for implant treatment.

The data stored in the integrated IC chip 122 is data that is continuously stored for a preset time interval, and includes blood-based biomarker and non-blood biomarker data of a target patient. Therefore, it is possible to more effectively and accurately determine the state of the target patient based on data continuously stored for a certain period and at a certain time interval.

In some cases, the processor unit unit 120 may be configured to further include a wireless communication device 124 that transmits data stored in the integrated IC chip 122 to the outside, as shown in FIG. 2.

In this case, data that is continuously stored for a preset time interval can be transmitted to the outside by using the wireless communication device 124. As a result, it is possible to monitor the condition of the target patient in real time.

In this case, what can be applied to the wireless communication device is not particularly limited as long as it can be stably applied without a foreign body feeling in the oral cavity of the target patient, for example, an RF wireless transceiver, a Wi-Fi device, and a Bluetooth device.

Meanwhile, a battery capable of charging and discharging, a self-powered device 125, or an RF-based energy generating device may be mounted on the inside or one side of the processor unit unit 120 according to the present embodiment.

The above-mentioned self-powered device 125 may be configured to include a piezoelectric element for generating power by receiving a pressing force from an oral mastication motion. In this case, the piezoelectric element is preferably mounted adjacent to the upper surface of the processor unit 120 so as to effectively receive a pressing force from the masticating motion of the target patient. In addition, a capacitor for storing power generated from the piezoelectric element may be mounted inside the processor unit unit 120.

In addition, the above-mentioned RF-based energy generating device may have a configuration including an induction coil having a loop structure surrounding the outer circumferential surface of the processor unit unit 120. The induction coil is a component that generates power by using electromagnetic induction, and can generate power through a change in magnetic flux provided from the outside. In addition, a capacitor for storing power generated from the induction coil may be mounted inside the processor unit unit 120.

FIG. 6 is a block diagram illustrating a system for monitoring high-risk elderly diseases according to an embodiment of the present invention, and FIG. 7 is a schematic diagram illustrating a system for monitoring a system for constantly monitoring dangerous elderly diseases according to an embodiment of the present invention. Is shown.

Referring to these drawings, the high-risk elderly disease constant monitoring system 200 according to the present embodiment, as a configuration including the implant 100 according to the present invention, the information extracting unit 210 and information delivery to perform a specific role It may be a configuration including the unit 220.

The information extracting unit 210 according to the present embodiment is configured to receive data from the processor unit 120 of the implant 100 and then determine the state of the human body based on the transmitted data and store result data.

Specifically, when a target patient undergoes a regular dental examination, after removing the implant 100 from the target patient, data stored in the processor unit 120 of the implant 100 can be extracted using the information extraction unit 210 have.

The data extracted through the information extraction unit 210 is stored in a computer through the information delivery unit 220, or is used as precise diagnosis data when treating a specialized hospital for each disease.

When the target patient's condition rapidly deteriorates, the processor unit 120 of the implant 100 may notify the emergency situation and the patient's location information to a hospital or emergency room through a smart device in possession of the patient. In this case, an alarm such as an emergency alarm may be output to the patient to enable emergency treatment of the patient.

As described above, according to the high-risk elderly disease monitoring system of the present invention, the configuration for power supply can be compactly configured, so that the overall structure of the implant can be miniaturized, and desired data can be easily extracted from the target patient. . In addition, it is possible to solve the problems of the medical management system according to the prior art, in which the accessibility of the elderly patient is very weak, and to implement an effective and rapid health care management system for high-risk elderly diseases.

In addition, according to the constant monitoring system for high-risk elderly diseases of the present invention, it is possible to implement an innovative health care system by targeting three representative high-risk elderly diseases, and by using multiple sources such as blood biomarkers and non-blood biomarkers. Personalized precise diagnosis is possible, and by using an implant that includes a configuration capable of two-way wireless operation, it can effectively cope with emergency situations, and maximize accessibility and convenience by utilizing the clinical and industrial advantages of dental units and dental implants. .

In the above detailed description of the present invention, only special embodiments according thereto have been described. However, it should be understood that the present invention is not limited to a particular form mentioned in the detailed description, but rather, it is understood to include all modifications, equivalents, and substitutes within the spirit and scope of the present invention as defined by the appended claims. Should be.

That is, the present invention is not limited to the specific embodiments and description described above, and any person having ordinary knowledge in the technical field to which the present invention pertains without departing from the gist of the present invention claimed in the claims, various modifications are implemented. It is possible, and such modifications will fall within the protection scope of the present invention.

100: implant
101: artificial tooth (crown)
110: sensor unit (fixture)
111: first sensor
112: data transmission line
113: thread
114: connection terminal
120: processor unit (abutment)
121: second sensor
122: integrated IC chip
123: communication antenna
124: wireless communication device
125: self-powered device
126: bolt head
127: thread
128: connection terminal
200: High-risk elderly disease constant monitoring system
210: information extraction unit
220: information transmission department

Claims (13)

The first sensor 111 has a hollow structure in which a thread is formed on the outer circumferential surface so that it is placed in the oral cavity of the human body, and a thread is formed on the inner circumferential surface so that the processor unit 120 can be bolted therein, and wraps the thread formed on the outer circumferential surface. The sensor unit unit 110 is mounted; And
A bolt structure having a screw thread formed on the outer surface so as to be bolted to the sensor unit unit 110, a communication antenna 123 is mounted in a form surrounding the thread formed on the outer peripheral surface, and a second sensor 121 is mounted on the outer surface And, the processor unit unit 120 on which the integrated IC chip 122 for storing the data detected from the first sensor 111 and the second sensor 121 and transmitting the stored data to the outside is mounted; an implant ( 100);
After receiving data from the processor unit 120 of the implant 100, an information extracting unit 210 that determines the state of the human body based on the transmitted data and stores result data; And
Including; an information transmission unit 220 that determines whether there is an emergency situation based on the result data obtained through the information extraction unit 210, and transmits the emergency situation and the patient's location information to an emergency room or hospital in case of an emergency. But,
The first sensor 111 mounted on the outer circumferential surface of the sensor unit 110 is a blood sensor that detects a blood biomarker,
The second sensor 121 mounted on the outer circumferential surface of the processor unit 120 is a sensor for detecting a non-blood biomarker from gingival fissure or saliva.
The method of claim 1,
The sensor unit unit 110 is a high-risk elderly disease constant monitoring system, characterized in that the artificial tooth root (fixture) structure to be placed in the upper or lower jaw in the oral cavity of the human body.
The method of claim 2,
The processor unit unit 120 is bolted to the sensor unit unit 110, the high-risk elderly disease constant monitoring system, characterized in that the abutment (abutment) structure in which the artificial tooth 101 can be mounted on the upper part.
The method of claim 1,
The integrated IC chip 122, a data storage unit for storing the data detected from the first sensor 111 and the second sensor 121; High-risk elderly disease constant monitoring system comprising a.
The method of claim 1,
The processor unit unit 120, a wireless communication device (124) for transmitting the data stored in the integrated IC chip (122) to the outside; High-risk elderly disease constant monitoring system comprising a.
The method of claim 1,
A high-risk elderly disease constant monitoring system, characterized in that a battery capable of charging and discharging, a self-powered device 125, or an RF-based energy generating device is mounted inside or on one side of the processor unit 120.
The method of claim 6,
The self-powered device 125,
A piezoelectric element mounted adjacent to the upper surface of the processor unit 120 and receiving pressing force from an intraoral mastication motion to generate electric power; And
A high-risk elderly disease constant monitoring system comprising; a capacitor mounted inside the processor unit 120 and storing power generated from the piezoelectric element.
The method of claim 6,
The RF-based energy generating device,
An induction coil having a loop structure surrounding the outer peripheral surface of the processor unit unit 120; And
A high-risk elderly disease constant monitoring system comprising a; a capacitor mounted inside the processor unit 120 and storing power generated from the induction coil.
delete delete The method of claim 1,
The second sensor 121 is a high-risk elderly disease constant monitoring system, characterized in that it is mounted on the areas (P1, P2) adjacent to the gingival fissure formed on the interface between the artificial tooth 101 and the gum.
delete The method of claim 1,
The processor unit 120 of the implant 100 repeatedly detects data from the first sensor 111 and the second sensor 121 during a preset time interval, and then stores the detected data by time. High-risk elderly disease constant monitoring system.

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