KR102106212B1 - hypo-allergenic manicure composition by shellac for nail and toenail and its product method - Google Patents

Abstract

The present invention relates to a hypoallergenic nail polish composition for nails using shellac and a method for manufacturing the same, and in detail, a hypoallergenic nail polish composition for nails using shellac that can replace nitrocellulose, resin, plasticizer, and organic solvent harmful to the human body, and It relates to his manufacturing method.
Hypoallergenic nail polish composition for nails using shellac of the present invention is a hypoallergenic nail polish composition containing shellac used as a pharmaceutical coating agent, and ethyl acetate, which is highly harmful without using nitrocellulose, resin, or plasticizer, which may be harmful to the human body, Ester and ketone solvents such as butyl acetate, acetone, and methyl ethyl ketone are replaced with ethanol and isopropyl alcohol, and when applied to nails, they have a function or form as a nail polish, and at the same time, they are harmless to the human body and can be expected to have improved odor. .

Description

Hypoallergenic manicure composition for nails using shellac and its manufacturing method {hypo-allergenic manicure composition by shellac for nail and toenail and its product method}

The present invention relates to a hypoallergenic nail polish composition for nails using shellac and a method for manufacturing the same, and more specifically, nitrocellulose, which can be harmful to the human body, is shellac and polyvinylpyrrolidone, and has strong irritation and toxicity. , By replacing organic solvents such as butyl acetate with ethanol and isopropyl alcohol, it relates to a hypoallergenic nail polish composition for nails using shellac, which is harmless to the human body and has improved odor, and a method for manufacturing the same.

Manicure is a kind of color cosmetics used to protect nails and decorate fingertips beautifully. Recently, the nail art market is increasing not only in Korea but also abroad.

As a conventional patent technology, in Patent Publication No. 10-2017-0120784, in an aqueous nail polish composition comprising an acrylic polyurethane aqueous dispersion and hydrophilic silica, polyether-modified polydimethylsiloxane 0.1 to 0.5% by weight, triethylene glycol mono An aqueous nail polish composition is disclosed, characterized in that it contains 1 to 3% by weight of butyl ether and 1 to 3% by weight of a polyester aqueous dispersion.

In addition, the registered patent publication No. 10-1485805 includes a liquid base 100 parts by weight; 3 to 15 parts by weight of a luminous pigment and a ionic pigment; CNT (carbon nanotubes) 0.3 to 1.5 parts by weight and; It is composed of 4 to 15 parts by weight of calcium carbonate coated with stearic acid, and the liquid base comprises 20 to 43 wt% of a film forming agent composed of nitrocellulose and a vinyl-based synthetic resin based on 100 wt% of the total weight of the liquid base, A multicolored nail polish composition is disclosed, characterized in that it comprises 2 to 13 wt% of a camphor or ethyl benzoate plasticizer and 44 to 68 wt% of a solvent selected from acetone, ethyl alcohol and ethyl acetate.

In addition, the components of nail polish are largely composed of four components: a film-forming component, a solvent component, a coloring component, and an anti-sedimentation component.

Of these, the film-forming component is composed of nitrocellulose, alkyd resin, sulfonamide resin, sucrose-based resin, camphor, citric acid ester, camphor, and the like, and nitrocellulose and alkyd resin are most commonly used. However, nitrocellulose is unstable to heat, so there is a risk of explosion at high concentration, and there is a disadvantage that severe odor occurs.

In addition, the solvent component used for manicure must be dissolved in nitrocellulose, resin, plasticizer, etc. to adjust the viscosity to have an appropriate feeling of use and to have a proper volatilization rate. Is used. In particular, these organic solvents contain a large amount of highly volatile components and are absorbed into the human body through the respiratory system, so symptoms such as headache, dizziness, loss of appetite, memory impairment, and menstrual impurity may be required.

It can also cause allergic reactions in some people, and frequent use of manicure can cause shape changes such as thinning of nails or toenails, C-curves or straight nails, and nail or toenail cracks or broken nails. It can cause the same disease.

Therefore, the manicure manufacturing process is a representative environmentally polluted process, and there is a problem that has a very negative impact on the health and hygiene environment of workers and consumers in the manufacturing workshop and nail art shops.

On the other hand, shellac is a natural resin made by extracting insect fluids and secretions of female Lac-bug living in India and Thailand, and is used as an eco-friendly paint, food glaze, or pharmaceutical coating.

Shellac is a natural bio-adhesive plastic that is chemically similar to synthetic polymers, and has good durability and coating ability when dissolved in denatured alcohol or ethanol.

However, there is no conventionally known hypoallergenic nail polish composition for nails using shellac.

Therefore, the present invention was devised to solve the above problems, and the present invention is to improve the problems of the conventional nail polish composition, and provides a hypoallergenic nail polish composition for nails using shellac that is harmless to the human body and has improved odor. The purpose.

Another object of the present invention is to provide a method of manufacturing a hypoallergenic nail polish composition for nails using shellac having a non-toxic and stable formulation as a composition having a function or form as a nail polish having water resistance, coatability, and dryness. .

In order to solve the above problems, the present invention provides a hypoallergenic nail polish composition for nails using shellac containing shellac as a film-forming agent as a hypoallergenic nail polish composition for nails.

In the present invention, in the hypoallergenic nail polish composition for nails using shellac, the shellac is characterized by being included in a ratio of 15 to 30 parts by weight per 100 parts by weight of the nail polish composition. In the present invention, in the hypoallergenic nail polish composition for nails using shellac, when the shellac is less than 15 parts by weight, the effect of forming a film does not appear due to the addition of shellac, and when it exceeds 30 parts by weight, there is a fear that the stability of the formulation is inhibited.

Hypoallergenic nail polish composition for nails using shellac of the present invention is an auxiliary film-forming agent selected from the group consisting of acrylate copolymers, polyvinylpyrrolidone, polyvinyl alcohol, camphor, hydroxypropylmethylcellulose and rosin gum. It is characterized by including more than a species.

The auxiliary film forming agent is characterized in that it is included in a proportion of 2 to 5 parts by weight per 100 parts by weight of the nail polish composition.

The hypoallergenic nail polish composition for nails comprising shellac of the present invention is characterized in that it contains at least one in the group consisting of a solvent, a surfactant, a brightener, a colorant, an anti-settling agent and a water repellent.

The colorant is characterized in that it is at least one selected from black iron oxide, red iron oxide, yellow iron oxide, red No. 2 colorant, black No. 401 colorant, SL-6003S pearl pigment colorant and titanium dioxide.

The brightener is characterized in that the carnauba wax, bead wax and candelilla wax are used by dissolving 5 to 20 parts by weight per 100 parts by weight in oleyl alcohol.

The anti-settling agent is characterized by citric acid and ethylenediaminetetraacetic acid.

In addition, the present invention is a method of manufacturing a hypoallergenic nail polish composition for nails using shellac, comprising shellac; An auxiliary film forming agent; It provides a method of manufacturing a hypoallergenic nail polish composition for nails using shellac, characterized in that it comprises; mixing, further comprising one or more from the group consisting of a solvent, a surfactant, a brightener, a colorant, an anti-settling agent, and a water repellent.

In the method of manufacturing the nail polish composition according to the present invention, the solvent is characterized in that ethanol and isopropyl alcohol. In the method for manufacturing a nail polish composition according to the present invention, a shellac solution is prepared by using the solvent.

Hypoallergenic manicure composition for nails using shellac according to the present invention and its manufacturing method, because natural resin and hypoallergenic organic solvent were used instead of explosive nitrocellulose and toxic organic solvent.

1) It is safe because there is no danger of fire or explosion that may occur during production.

2) The odor is improved to prevent side effects that can be absorbed and absorbed through the respiratory system.

3) Natural friendly and non-toxic, harmless to human body

Has a remarkable effect.

1 to 3 are the results of the viscosity change by evaluating the stability of the nail polish composition prepared by the present invention
Figure 4 is the result of the change in the coating properties by evaluating the stability of the nail polish composition prepared by the present invention
5 is a result of the cytotoxicity test as a safety evaluation of the nail polish composition prepared by the present invention

Hereinafter, the present invention will be described in more detail by examples. However, the present invention is not limited by the following examples.

[Example 1] Preparation of shellac solution composition

1.1. Preparation of shellac solution using ethanol

10 to 40 parts by weight of shellac resin, 60 to 90 parts by weight of ethanol are mixed, dissolved in an airtight container and dissolved in an ultrasonic grinder at a temperature of 60 ° C for 90 to 120 minutes to prepare a shellac solution composition.

1.2. Preparation of shellac solution using isopropyl alcohol

10 to 40 parts by weight of shellac resin, 60 to 90 parts by weight of ethanol are mixed, and dissolved in an airtight container at a temperature of 60 ° C. for 120 minutes to 150 minutes with a sonicator to prepare a shellac solution composition.

[Example 2] Preparation of carnauba wax solution composition

5 to 20 parts by weight of carnauba wax, 80 to 95 parts by weight of oleyl alcohol are mixed, dissolved in an airtight container and dissolved in an ultrasonic grinder for 10 to 20 minutes at a temperature of 60 ° C. to prepare a carnauba wax solution composition. .

[Example 3] Preparation of hypoallergenic nail polish composition for nails using shellac

A nail polish composition was prepared according to the [Example 4] manufacturing method with the composition (unit: parts by weight) shown in Table 1 below.

Raw material name #Gold
(#G) #Yellow
(#Y) #Red
(#R) #Black
(#B) Ethanol
Shellac solution 15 to 35 10 to 30 35 to 55 35 to 55 Citric Acid 1 to 3 1 to 3 1 to 3 1 to 3 Polyethylene glycol 600 1 to 3 1 to 3 1 to 3 1 to 3 Polysorbate 80 1 to 3 1 to 3 1 to 3 1 to 3 Polyvinylpyrrolidone 2 to 5 2 to 5 2 to 5 2 to 5 Using isopropyl alcohol
Shellac solution 50 to 70 60 to 80 35 to 55 35 to 55 Carnauba wax solution 1 to 3 1 to 3 1 to 3 1 to 3 Dimethicone 1 to 3 1 to 3 1 to 3 1 to 3 Propylene glycol 1 to 3 1 to 3 1 to 3 1 to 3 Iron oxide (oxide / yellow) 1 to 2 1 to 3 - - Iron oxide (oxide / red) - - 1 to 5 - Iron oxide (oxide / black) - - - 1 to 5 Tar color (Red No. 2) - - - 0 to 1 Tar color (Black 401) - - - 0 to 1 Pearl pigment (SL-6003S) 1 to 4 - - - Titanium dioxide 1 to 2 1 to 3 - 0 to 1 Sum 100 100 100 100

[Example 4] Preparation of hypoallergenic nail polish composition for nails using shellac

The general manufacturing method of the hypoallergenic nail polish composition for nails using shellac is as follows.

1) Put shellac solution using ethanol into a beaker, add citric acid, polyethylene glycol 600 and polysorbate 80, and mix.

2) Polyvinylpyrrolidone is slowly added and stirred to prevent lump formation.

3) The shellac solution using isopropyl alcohol, the carnauba wax solution, dimethicone, propylene glycol, and colorant are mixed in order.

4) The entire mixture is mixed for 30 to 60 minutes to prepare a nail polish composition. At this time, the stirring speed is performed at 1000 to 1500 rpm.

Basically, the above manufacturing method is followed, but when tar color is added as a colorant, the tar color is less soluble in an isopropyl alcohol solvent, so the manufacturing method is different as follows.

1) Put shellac solution using ethanol into a beaker, add citric acid, polyethylene glycol 600 and polysorbate 80, and mix.

2) Polyvinylpyrrolidone is slowly added and stirred to prevent lump formation.

3 ') Carnauba wax solution, dimethicone, propylene glycol, and colorant are mixed in order and mixed for 10 to 20 minutes. At this time, the stirring speed is performed at 1000 to 1500 rpm.

4 ') The shellac solution using propyl alcohol was added last, and the entire mixture was mixed for 20 to 40 minutes to prepare a nail polish composition. At this time, the stirring speed is performed at 1000 to 1500 rpm.

[Example 5] Performance evaluation of hypoallergenic nail polish composition for nails using shellac

The performance evaluation of the nail polish composition prepared through the above [Example 3] and [Example 4] was carried out in the following manner, and the results are summarized in [Table 2].

 5.1. Skin irritation evaluation

The composition was applied to the nails, and differences in skin keratin changes and skin dryness were observed and evaluated. The evaluation methods were evaluated as ○: good, Δ: normal, and X: poor.

 5.2. Odor evaluation

When applying the composition to the nail, the difference in the degree to which an unpleasant or disgusting smell is smelled was evaluated by smell. The evaluation methods were evaluated as ○: good, Δ: normal, and X: poor.

 5.3. Water resistance evaluation

The composition was applied to nails, and the difference in the degree of peeling off by running tap water was observed and evaluated. The evaluation methods were evaluated as ○: good, Δ: normal, and X: poor.

 5.4. Applicability evaluation

The composition was applied to nails, and differences in the degree of suspension or pinholes on the dried film were observed and evaluated. The evaluation methods were evaluated as ○: good, Δ: normal, and X: poor.

 5.5. Dryness evaluation

Since the general manicure composition dries within 3 to 5 minutes, it was evaluated by measuring the time at which the composition disappears when applied to the nail and lightly touched with fingertips at 30 second intervals.

Evaluation items #Gold
(#G) #Yellow
(#Y) #Red
(#R) #Black
(#B) Skin irritation ○ ○ ○ ○ smell ○ ○ ○ ○ Water resistance ○ ○ ○ ○ Applicability ○ ○ ○ ○ Dryness 4 minutes to 4 minutes 30 seconds or less 4 minutes to 4 minutes 30 seconds or less 4 minutes to 4 minutes 30 seconds or less 4 minutes to 4 minutes 30 seconds or less

As a result of performing the performance evaluation of the hypoallergenic nail polish composition for nails using shellac, as shown in [Table 2], there is no odor and skin irritation, and is a harmless to manicure composition. It was evaluated as a composition having a function or form.

[Example 6] Evaluation of stability of hypoallergenic nail polish composition for nails using shellac

The stability evaluation of the nail polish composition prepared through the above [Example 3] and [Example 4] is prepared in a sealed container made of plastic material, and stored at 4 ℃, Room Temperature (25 ℃), and 40 ℃ by shading. The changes were recorded on the 0th, 1st, 2nd, 3rd, 5th, 1st week, 2nd week, 3rd week, and 4th week as follows.

 6.1. Viscosity change evaluation

The rotation speed of the viscometer spindle was measured at 60 rpm to measure the viscosity (unit: cP), and the change was recorded. The results are summarized in [Table 3] and [Drawings 1 to 3].

　
　 0 days 1 day 2 days 3 days 5 days 7 days 14 days 21 days 28 days STD STD
(%) 4 ℃ #G 255.0 179.5 223.5 172.0 177.0 213.0 196.5 136.0 159.0 36.1 14.1 #Y 238.5 195.0 203.5 244.5 200.0 181.5 143.5 140.0 184.0 36.0 15.1 #R 192.5 136.0 166.0 116.0 140.5 143.0 105.0 107.0 112.0 29.4 15.3 #B 225.5 225.5 210.0 136.0 189.0 194.5 181.5 131.5 143.5 36.9 16.4 RT
(25 ℃) #G 255.0 246.5 225.5 183.5 231.5 192.0 210.5 181.0 160.0 32.5 12.7 #Y 238.5 191.5 181.0 165.5 181.0 195.5 181.0 162.0 162.0 23.7 9.9 #R 192.5 156.0 164.0 142.5 136.5 136.5 121.5 128.5 117.5 23.6 12.3 #B 225.5 212.0 210.5 181.0 196.0 183.0 151.0 126.0 124.5 37.3 16.5 40 ℃ #G 255.0 141.0 151.0 140.0 135.0 130.0 108.5 104.0 112.5 45.4 17.8 #Y 238.5 151.0 156.0 121.5 141.5 148.0 129.5 125.5 130.0 35.7 14.9 #R 192.5 156.5 128.0 112.0 104.5 103.5 103.0 121.5 123.5 29.7 15.4 #B 225.5 176.0 107.0 121.5 103.0 111.5 106.5 106.0 107.5 42.6 18.9

 6.2. Evaluation of coating property change

The difference in the degree of suspension or pinhole formation on the dried film coated with artificial nails was visually observed to record the change. The evaluation methods were evaluated as O: good and X: poor, and the results are shown in [Table 4] and [Fig. 4].

0 days 1 day 2 days 3 days 5 days 7 days 14 days 21 days 28 days #G 4 ℃ ○ ○ X X X ○ ○ X X RT (25 ℃) ○ X X X X X ○ ○ X 40 ℃ ○ ○ X ○ X X ○ X ○ #Y 4 ℃ ○ ○ X X X X ○ X X RT (25 ℃) ○ ○ X X X X ○ ○ ○ 40 ℃ ○ ○ X X X ○ ○ X X #R 4 ℃ ○ ○ ○ X ○ ○ ○ ○ ○ RT (25 ℃) ○ ○ ○ ○ ○ ○ ○ ○ ○ 40 ℃ ○ ○ ○ ○ ○ ○ ○ ○ ○ #B 4 ℃ ○ ○ ○ ○ ○ ○ ○ ○ ○ RT (25 ℃) ○ ○ ○ ○ ○ ○ ○ ○ ○ 40 ℃ ○ ○ ○ ○ ○ ○ ○ ○ ○

As a result of the stability evaluation of the hypoallergenic nail polish composition for nails using shellac, the time after preparing the nail polish composition as shown in [Table 3] and [Table 4], [Figures 1 to 3] and [Figure 4] Over time, the formulation was stabilized, and the nail polish composition blended in black was judged to be the most stable formulation.

[Example 7.] Safety evaluation of hypoallergenic nail polish composition for nails using shellac

The safety evaluation of the nail polish composition prepared through the above [Example 3] and [Example 4] is a test performed to determine whether the product has no toxicity or irritation, and is a cytotoxicity test, one of the animal replacement test methods. To evaluate the risk of manicure. The MTT assay was performed as follows, and the quantity of MTT was calculated by modifying the Mosmann method.

1) B16F10 mouse melanoma cells are grown in DMEM medium with 10% FBS added at 37 ° C and 5% CO2 incubator.

2) Dispense the grown cells into 96 wells at 1 × 104 cell / mL and incubate for 24 hours.

3) Replace with a new medium to which samples of extracts diluted to concentrations of 0.1, 0.5, 1, 5, and 10 mg / mL are added, and incubate for 24 hours.

4) After 24 hours, 20 μL of each well was added to MTT (3- (4,5-dimethylthiazol-2-yl) -2,5-diph enyltetr azolium bromide), followed by 2 hours at 37 ℃ and 5% CO2 incubator Incubate.

5) After 2 hours, the formed fomazan was dissolved with 200 μL DMSO, and the absorbance was measured with an ELISA reader at 595 nm to calculate cell viability.

Cell viability (%) = [(experimental group-blank) / control] X 100

The results are shown in [Table 5] and [Fig. 5].

0mg / mL 0.1mg / mL 0.5mg / mL 1mg / mL 5mg / mL 10mg / mL #G 100 ± 2.0 98.4 ± 1.9 92.8 ± 3.3 85.5 ± 3.2 81.7 ± 3.3 76.0 ± 3.7 #Y 100 ± 3.8 96.7 ± 4.1 90.3 ± 5.5 84.7 ± 5.2 79.0 ± 4.5 78.4 ± 2.5 #R 100 ± 1.5 97.0 ± 1.9 87.5 ± 2.3 80.2 ± 5.5 79.0 ± 2.7 76.2 ± 2.5 #B 100 ± 3.5 94.2 ± 6.1 89.5 ± 2.0 84.1 ± 3.1 79.4 ± 5.3 77.8 ± 2.4

As a result of conducting a safety evaluation of the hypoallergenic nail polish composition for nails using shellac, as shown in [Table 5] and [Figure 5], it was evaluated as a safe and natural friendly nail polish composition without toxicity.

As described above, the present invention has demonstrated the superiority of its physical properties through the above-described embodiments, but the present invention is not limited to the above-described embodiments, and various substitutions, modifications, and modifications are possible without departing from the spirit of the invention. Do.

Claims (3)

Shellac solution composition; An auxiliary film forming agent; In the method of manufacturing a hypoallergenic nail polish composition for nails using shellac comprising; mixing, further comprising at least one of each of a group consisting of a solvent, a surfactant, a brightener, a colorant, an anti-settling agent and a water repellent;
The shellac solution composition is prepared using ethanol, 10 to 40 parts by weight of a shellac resin, 60 to 90 parts by weight of ethanol, mixed, and placed in a closed container at 60 ° C for 90 minutes to 120 minutes using an ultrasonic grinder (sonication). Dissolving to prepare a shellac solution composition,
The auxiliary film-forming agent is a shellac, characterized in that it comprises at least one selected from the group consisting of acrylate copolymers, polyvinylpyrrolidone, polyvinyl alcohol, camphor, hydroxypropyl methylcellulose, and rosin gum. Method of manufacturing a hypoallergenic nail polish composition for nails using A hypoallergenic manicure composition for nails using shellac, characterized in that a hypoallergenic manicure composition for nails using shellac is prepared by the method for preparing a hypoallergenic nail polish composition for nails using shellac of claim 1.
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