KR101567781B1 - A Shelf of Irradiation Apparatus - Google Patents

Abstract

The present invention relates to a radiation stand of an irradiation apparatus. The present invention provides the radiation stand of the irradiation apparatus capable of emitting the same amount of radiation to radiation targets to receive the radiation. The present invention includes a plurality of unit shelves and a lateral side.

Description

A Shelf of Irradiation Apparatus.

The present invention relates to an irradiation stage of a radiation irradiation apparatus, and more particularly to an irradiation stage of a radiation irradiation apparatus capable of uniformly irradiating all the radiation irradiated from a radiation irradiation apparatus to a receiving case provided in a unit shelf.

An irradiation apparatus is an apparatus for irradiating radiation to blood products, cells and tissues and skin tissues, bones and research animals, and its radiation field size is determined by a radiation collimator.

Specifically, an open hole of the radiation collimator is formed in a rectangular shape having a horizontal irradiation angle of 60 ° from both sides of the central axis of the radiation and an upward and downward irradiation angle of 20 ° and 40 °, respectively, The dose can be calculated according to the distance and time of the subject to be examined and the biological change can be observed.

Such radiation studies, that is, biological studies by radiation, are generally used in all phases of clinical trials using small animals such as experimental mice, since it is impossible to target the human body.

Conventional laboratory animal irradiation studies were designed to irradiate multiple experimental mice in a cage.

However, in the case of the above-described method, irradiation is performed on cages accommodating three to five animals, so that the objects to be irradiated overlap with the source of the irradiation apparatus. Due to the overlapping phenomenon, the experimental mice have different dose values for each mouse.

That is, since the distances between the irradiation device and the experimental mouse are different from each other, an error occurs, and even when the examination of the experimental mouse is required, there is a problem that it is difficult to expect a reliable result.

Therefore, it is preferable to irradiate the mouse cage after arranging the mouse cage in consideration of the characteristics of the collimator inlet of the irradiation device. However, due to time problems and installation errors, There was a difficulty in irradiating the radiation.

Therefore, there is a need for a radiation irradiation apparatus that can be irradiated at the same distance between the irradiation apparatus and the irradiation object.

Korean Patent Registration No. 10-0458365

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned problems, and it is an object of the present invention to provide a radiation examination unit of a radiation irradiation apparatus which is adjustable so that irradiation objects irradiated with radiation can all be irradiated with the same amount of radiation.

According to an aspect of the present invention,

A plurality of unit shelves stacked in a vertical direction; And a side part fixing the unit shelves, wherein the unit shelves are formed so that the radiation irradiated from the irradiation device can be uniformly irradiated to the accommodating case provided in the unit shelf.

The unit shelf is fitted in a guide groove for a unit shelf formed on the inner side of the side portion and can slide in the forward and backward directions.

A fixing protrusion is formed on an upper surface of the unit shelf, a fixing groove is formed in a bottom surface extending portion of the receiving case, and a fixing groove is fitted in the fixing protrusion, so that the receiving case can be fixed.

The fixing groove may be formed in an arc shape.

Wherein the accommodating case comprises: a base plate on which the fixing groove is formed; A body on which an animal is carried on the base plate to form a receiving space; An opening / closing unit provided to one side of the body so that the animal can be loaded and unloaded; A receiving part provided on the upper part of the body, wherein a part of the receiving part is inserted into the receiving space and the feed is embedded; And a fixing member protruding outward from one side of the body so that a water bottle can be installed on one side of the body.

The animal feeder may further include at least one feed port for feeding feed contained in the storage unit. The animal feeder may be capable of sucking the animal through an opening formed in one side of the body.

In addition, the receiving case may be formed of a transparent material.

On the other hand, according to the present invention,

A plurality of unit shelves stacked in a vertical direction; A side part fixing the unit shelves; And a guide groove formed on the upper surface of the unit shelf and in which a bottom guide of the housing case is inserted. According to the positional adjustment of the housing case, the radiation irradiated from the irradiation device is irradiated uniformly in the housing case .

INDUSTRIAL APPLICABILITY As described above, the irradiation zone of the irradiation apparatus according to the present invention can be irradiated uniformly to the irradiation case provided in the unit shelf.

Further, the irradiation case of the irradiation apparatus according to the present invention is advantageous in that the receiving case can be attached to and detached from the unit shelf, and the number of irradiation targets that can be tested at one time can be appropriately adjusted.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a view showing an irradiation table of a radiation irradiation apparatus according to an embodiment of the present invention; FIG.
FIG. 2 is a view showing an irradiation table of the irradiation apparatus according to another embodiment of the present invention; FIG.
FIG. 3 is a view showing an irradiation table of the irradiation apparatus according to another embodiment of the present invention; FIG.
4 is a view showing a receiving case according to the present invention;
Figure 5 is a schematic representation of Figure 1;
6 is a view showing Embodiment 1-1;
7 is a view showing Embodiment 1-2;
8 is a view showing Embodiment 1-3;
9 is a view showing Embodiment 2; And
10 is a view showing Comparative Example 1. Fig.

Hereinafter, the present invention will be described in more detail with reference to examples and the like, but the following examples are intended to illustrate the present invention, and the scope of the present invention is not limited thereto.

The irradiating unit of the irradiation apparatus of the present invention includes a plurality of unit shelves stacked in a vertical direction; And a side part for fixing the unit shelves, wherein the unit shelf is irradiated with the radiation irradiated from the irradiation device in the same manner as the case of the unit shelf.

The radiation source of the irradiation apparatus is irradiated radially starting from a point. When the irradiation is performed at a certain distance, the distance should be adjusted not only by the irradiation angle but also by the irradiation object. To this end, the present invention can achieve this by adjusting the unit shelf and the receiving case.

Meanwhile, the 'object to be irradiated' used in the present invention may be collectively referred to as a receiving case including a laboratory animal or a laboratory animal, or a receiving case, unless otherwise specifically limited.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a view of an irradiation table 200 of a radiation irradiation apparatus according to an embodiment of the present invention.

1, the irradiation table 200 of the irradiation apparatus 110 includes a plurality of unit shelves 220 stacked in the vertical direction and a side portion 240 fixing the unit shelves 220, The shelf 220 is configured such that the radiation irradiated from the irradiation device 110 can be uniformly irradiated to the case 260 provided in the unit shelf 220.

First, the unit shelf 220 is stacked and fixed in a plurality of vertical directions between the left and right side portions 240 fixed vertically on the paper. At this time, the unit shelf guide grooves 242 are formed in the width direction inside the left and right side portions 240 and the unit shelf 220 is formed inside the unit shelf guide grooves 242 to be slidable. This operation can control the distance between the irradiation device 110 and the object to be irradiated, thereby controlling the intensity of the radiation.

In order to prevent the unit shelf 220 from falling in the rear direction when the unit shelf 220 is engaged with the unit shelf guide grooves 242 and inserted in the rear direction (arrow direction) A stopper (not shown) may be formed at the end of the guide groove 242. In addition, a roller (not shown) may be further provided in a region where the unit shelf guide groove 242 and the unit shelf 220 are in contact with each other for smooth sliding.

(Not shown) may be additionally formed between the left and right side portions 240 between the left and right side portions 240 in order to stably maintain the shape of the irradiation table 200 when the irradiation table 200 is installed upright. (Not shown) for connecting the first and second light emitting diodes.

Each of the unit shelves 220 and the side portions 240 may have a predetermined size and thickness in a plate shape so as to accommodate a predetermined object, Stainless steel or the like.

The irradiation table 200 according to the present invention includes a fixing protrusion 222 formed on a unit shelf 220 and a fixing groove 262 formed on a bottom surface extended portion of the accommodation case 260, The fixing groove 262 can be fitted. Therefore, the receiving case 260 is fixed to the unit shelf 220 and is rotatable in the left and right in a fixed state.

Specifically, the intensity of the radiation is inversely proportional to the distance square, so that the same distance to the object to be irradiated from the irradiation device 110 is required. 5, the unit shelves 220 are arranged such that the distances d ₁ , d _2, ..., d ₉ between the irradiation apparatus 110 and the receiving case 260 are all the same, A plurality of fixing protrusions 222 are formed in an arc shape (dotted line in Fig. 1) on the upper surface.

1, the fixing protrusions 222 are not limited as long as they protrude in a convex shape on the upper surface of the unit shelf 220. The plurality of fixing protrusions 222 may be spaced apart from each other by a predetermined distance Respectively.

2, the fixing protrusions 222 may be formed on the lower surface of the base plate 410 of the receiving case 260, instead of being formed on the upper surface of the unit shelf 220. In this case, And a fixing protrusion 266 may be formed on the top surface of the bottom plate 264. [

1 and 2, the fixing groove 262 is formed at a position corresponding to the fixing protrusion 222 and the fixing protrusion 222 of the accommodating case 260. As described above, The fixing groove 262 and the fixing protrusions 222 and 266 are fitted to each other to fix the housing case 260 and to rotate the housing case 260.

The fixing groove 262 is formed on the base plate 410 of the front surface of the body 420 And may be formed into a slit shape by perforating. The fixing groove 262 may have a size of 3/5 to 4/5 of the width of the housing case 260, and may be formed in an arc shape. By the fixing groove 262 formed in an arc shape, the housing case 260 can be moved left and right to adjust its position.

Also, since the accommodating case 260 can be detachably attached to the irradiation table 200, the number of irradiation targets can be selected and irradiated with the radiation.

The fixing protrusions 222 and 266 and the fixing groove 262 may be made of one material selected from the group consisting of nickel, brass, aluminum, copper, an alloy thereof, and iron coated with nickel on the outer surface .

3 is a view of the irradiation table 300 of the irradiation apparatus according to another embodiment of the present invention.

3, the irradiation table 300 of the irradiation apparatus 110 of the present invention includes a plurality of unit shelves 320 stacked in the vertical direction, a side portion 340 for fixing the unit shelves, And a pair of guide grooves 322 which are formed on the upper surface of the shelf 320 and into which the bottom guide 364 of the housing case 360 is inserted. 110 are formed so as to be uniformly irradiated to the containing case.

The unit shelf 320 is fixed between both side portions 340 fixed vertically on the paper surface and the unit shelf 320 is slid into the unit shelf guide grooves 342 of the side portion 340, Since it has been described above, it is omitted.

As a preferred example, the irradiation table 300 of the present invention may include a plurality of pairs of guide grooves 322 in the unit shelf 320 in the moving direction of the housing case 360.

Specifically, a plurality of guide grooves 322 may be formed in a state in which a pair of guide grooves 322 are spaced apart from each other at a predetermined interval. The width of the pair of guide grooves 322 is not limited to a great extent as long as it can be easily fastened to a pair of bottom guides 364 formed on both sides of the bottom of the housing case 360. [

The shape of the guide groove 322 and the bottom guide 364 are not limited as long as they are fastened to each other so that the position of the accommodation case 360 can be adjusted. The bottom surface guide 364 may be formed in a shape of '┏ ┓' or '┛┗' on both sides of the bottom surface of the housing case 360 And can be fastened to each other.

The length of each guide groove 322 may be equal to or smaller than the width of the upper surface of the unit shelf 320.

In some cases, the stopper 324 may be formed at the rear end of the guide groove 322 in the longitudinal direction. When the movement of the bottom guide 364 is stopped by the stopper 324, the movement of the receiving case 360 is completed do.

Since the guide groove 322 and the bottom guide 364 may be made of metal, the bottom guide 364 slides on the upper surface of the guide groove 322 and can slide smoothly.

That is, the guide grooves 322 and the bottom guide 364 are fastened and arranged side by side on the upper surface of the unit shelf 320. At this time, the accommodating case 360 can be arranged in an arcuate shape by appropriately adjusting the accommodating case 360 in the forward and backward directions, whereby the accommodating case 360 can receive the same amount of radiation from the irradiating device 110 . In addition, since the position of the housing case 360 can be adjusted differently, the amount of radiation irradiated by the housing case 360 can be adjusted.

Meanwhile, the case 400, 360, 260 used in the present invention will be described with reference to FIG.

The housing case 400, 360, 260 includes a base plate 410 on which a fixing groove is formed; A body 420 into which an animal is introduced to form a receiving space; An opening / closing part 422 provided so as to be openable / closable so as to carry the animal; A receiving portion 430 in which the feed is embedded; And a fixing member 440 on which a water bottle is installed.

The receiving cases 400, 360, and 260 including the base plate 410 can be detachably attached to the unit shelves 220 and 320.

In one preferred embodiment, the base plate 410 may be formed with fixing grooves 262 and 412 so that the accommodating cases 400, 360 and 260 are movable left and right on a unit shelf. The fixing grooves 262 and 412 may be formed in a slit shape through the base plate 410, and may be concave or convex, preferably circular arc.

In another preferred embodiment, the base plate 410 may be detachably attached to the guide groove 322 of the unit shelf 320. Bottom guides 450 and 364 are formed on the side extension of the base plate 410 and the bottom guides 450 and 364 are inserted into the guide groove 322 of the unit shelf 320 in a sliding manner, Thereby enabling coupling.

Since the fixing grooves 262 and 412 and the unit shelf 220 have been described above, detailed description will be omitted.

On the other hand, the body 420 is coupled with the base plate 410, and a receiving space is formed so that animals can be brought in. The size of the body 420 is not limited as long as it is large enough to accommodate a laboratory animal. Preferably, the body 420 is sized according to the ecological and habitat of an animal according to the ILAR Guide . The body 420 may be formed of a transparent material so as to observe the state of the animal being accommodated, and more preferably, it may be formed of a plastic material which is light and easy to handle. However, the present invention is not limited thereto.

The opening and closing part 422 may be provided to be openable and closable to one side of the body 420 so that the animal can be carried. The opening and closing part 422 may be slidably mounted on the body 420. The structure of the opening and closing part 422 and the body 420 is not limited thereto and any structure may be employed if the opening and closing part 422 is openable and closable. However, a perforation hole 428 may be formed in the upper part of the opening and closing part to facilitate opening and closing. The perforation hole 428 serves to facilitate opening and closing of the body 420, and also serves as a breathing hole for a laboratory animal.

The housing part 430 is formed on the upper part of the body 420. The housing part 430 is not particularly limited as long as it can house the feed, but it may be formed in a hopper shape in which the lower part of the housing part 430 is inserted into the accommodation space. The receiving portion 430 may have a built-in structure or a removable structure.

The receiving portion 430 may be formed with one or more feed ports 432 for feeding the animal feed to the laboratory animal. The feed outlet 432 may be formed at a lower portion of the receiver 430 and the shape of the feed outlet 432 is not particularly limited as long as the animal can feed the feed through the feed outlet 432. However, it is preferable that the feed outlet 432 is formed in a size that does not escape the laboratory animal through the feed outlet 432.

The fixing member 440 is formed to protrude to the outside of the body 420. The fixing member 440 may protrude outward from one side of the body 420 so as to include a water tank 462 for a laboratory animal.

The fixing member 440 may have a shape in which a through hole 442 is formed so that an animal water bottle 462 can be inserted. The front end of the water bottle 462 is inserted through the opening 424 formed at one side of the body 420. The water bottle 462 is inserted into the fixing member 440 through the opening 424 formed at one side of the body 420. The laboratory animal can suck water through the distal end of the water can 462 inserted into the opening 424. [

In some cases, a locking protrusion (not shown) may be formed to open and close the fixing member 440 within a predetermined distance from the body 420, and to fix the fixing member 440 firmly.

The respiratory passages 426 may be formed at one side of the body 420 to enable respiration of the contained animal. May be formed in various positions and sizes, but preferably on top of the body 420, as long as the lab animals received by the breathing through holes 426 can prevent choking during the experiment.

{Example}

[Example 1] Fabrication of a radiation irradiation apparatus

A radiation table of the irradiation apparatus was prepared. At this time, nine storage cases are arranged on the unit shelves of five levels in each layer, and numbers from the storage case no.1 on the left side to the storage case no.9 on the right side are numbered.

The distance or angle of the receiving case was measured with different distance (D) between the irradiation apparatus and the irradiation table. The results are shown below. The distance (D) between the irradiation apparatus and the irradiation station was set to 1M, 2M, 3M, 4M, and 5M, and the result was shown by the distance (D) between the irradiation apparatus and the irradiation station.

1-1. Adjust the position of unit shelves

6 is a view illustrating a position control of a unit shelf according to an embodiment of the present invention.

Referring to FIG. 6, each unit shelf is slid to adjust its position. At this time, the distance slid by each level was measured for each distance (D) between the irradiation apparatus and the irradiation table, and the results are shown in Table 1 below. In addition, the sliding distance of the unit shelf was measured based on the center of the case of 5 levels.

Distance Level 1 Level 2 Level 3 Level 4 Level 5 1M - - 158.34 37.14

Center

2M 316.67 171.37 74.28 18.31 3M 201.14 111.42 49.00 12.17 4M 148.56 82.87 36.62 9.12 5M 118.03 66.05 29.25 7.30

^{(Unit: mm)}

1-2. Adjust the position of the case

FIG. 7 is a view illustrating a receiving case whose position is adjusted according to an embodiment of the present invention. FIG.

As shown in FIG. 7, after adjusting the unit shelf according to the embodiment 1-1, the position of the receiving case is adjusted so that the distance of the radiation source becomes the same. At this time, the length (d) between the parallel line passing through the center of the receiving case No. 5 for each level and the parallel line passing the center point of each receiving case in the same layer was measured, and the results are shown in Table 2 below .

Distance Floor
Mouse Cage Position No.1 No.2 No.3 No.4 No.5 No.6 No.7 No.8 No.9 1M

5 20.53 116.27 52.25 13.15










center










13.15 52.25 116.27 203.53 4 195.97 111.95 50.31 12.66 12.66 50.31 111.95 195.97 3 171.90 97.86 43.98 11.07 11.07 43.98 97.86 171.30 2M



5 117.10 66.16 29.50 7.39 7.39 29.50 66.16 117.10 4 116.03 65.55 29.22 7.32 7.32 29.22 65.55 116.03 3 112.75 63.70 28.40 7.11 7.11 28.40 63.70 112.75 2 107.07 60.49 26.97 6.76 6.76 26.97 60.49 107.07 One 98.56 55.68 24.83 6.22 6.22 24.83 55.68 98.56 3M



5 79.12 44.60 19.85 5.02 5.02 19.85 44.60 79.12 4 78.80 44.41 19.77 4.95 4.95 19.77 44.41 78.80 3 77.83 43.87 19.52 4.89 4.89 19.52 43.87 77.83 2 76.19 42.94 19.11 4.78 4.78 19.11 42.94 76.19 One 73.82 41.61 18.52 4.68 4.68 18.52 41.61 73.82 4M



5 59.30 33.39 14.85 3.72 3.72 14.85 33.39 59.30 4 59.17 33.32 14.82 3.71 3.71 14.82 33.32 59.17 3 58.76 33.09 14.72 3.68 3.68 14.72 33.09 58.76 2 58.07 32.70 14.55 3.64 3.64 14.55 32.70 58.07 One 57.10 32.15 14.30 3.58 3.58 14.30 32.15 57.10 5M



5 47.31 26.63 11.84 2.96 2.96 11.84 26.63 47.31 4 47.24 26.59 11.83 2.96 2.96 11.83 26.59 47.24 3 47.04 26.48 11.77 2.95 2.95 11.77 26.48 47.04 2 46.69 26.28 11.69 2.92 2.92 11.69 26.28 46.69 One 46.20 26.00 11.56 2.90 2.90 11.56 26.00 46.20

^{(Unit: mm)}

1-3. Angle adjustment of case

FIG. 8 is a view illustrating an accommodating case adjusted in an angle according to an embodiment of the present invention; FIG.

As shown in FIG. 8, after adjusting the position of the housing case according to the embodiment 1-2, the housing case was rotated to the left and right to adjust the angle of each housing case.

At this time, with respect to a line segment connecting the center of the irradiation source with the center point of each accommodating case, the accommodating case is rotated such that the directions of the accommodating cases are perpendicular to each other, with the irradiation source of the radiating apparatus being the central point. Table 3 shows the results of measuring the angle (?) Of each case according to the measured irradiation angle.

포스 포스 위치 No.1 No.2 No.3 No.4 No.5 No.6 No.7 No.8 No.9 Counter Clock Wise

center
Clock Wise 1M (74.41) 37.20 27.90 18.60 9.30 9.30 18.60 27.90 37.20 2M (39.406 [deg.]) 19.70 14.78 9.85 4.93 4.93 9.85 14.78 19.70 3M (26.376) 13.19 9.90 6.59 3.30 3.30 6.59 9.90 13.19 4M (19.756 [deg.]) 9.88 7.41 4.94 2.47 2.47 4.94 7.49 9.88 5M (15.776) 7.89 5.92 3.94 1.97 1.97 3.94 5.92 7.89

^{(Unit: °)}

[Example 2: Measurement of radiation dose]

In accordance with the method of Example 1, the irradiation table of the irradiation apparatus was installed, and 23 mice each having a glass dosimeter inserted into the head portion and the body portion were housed one by one in a receiving case of the irradiation stage. Radiation of 0.1 Gy was irradiated so that the distance between the irradiation apparatus and the irradiation station was 2 m. The position of the mouse is shown in Fig.

[Comparative Example 1]

The same method as in Example 2 was used except that one or three mice were placed in a mouse cage using a shelf and a mouse cage sold on the market and irradiated with radiation.

On the other hand, the position of the mouse is shown in Fig.

[Experimental Example 1]

The mice irradiated with radiation according to Example 2 and Comparative Example 1 were taken out from the case. The head of the mouse and the glass dosimeter contained in the body were taken out and the doses were compared.

One) Example  Result according to 2

Mouse number Irradiation site Absorbed dose Mouse number Irradiation site Absorbed dose No.1
Head portion 0.096 No.13
Head portion 0.095 Body portion 0.096 Body portion 0.097 No.2
Head portion 0.097 No.14
Head portion 0.098 Body portion 0.096 Body portion 0.099 No.3
Head portion 0.095 No.15
Head portion 0.094 Body portion 0.096 Body portion 0.095 No.4
Head portion 0.094 No.16
Head portion 0.096 Body portion 0.095 Body portion 0.097 No.5
Head portion 0.097 No.17
Head portion 0.100 Body portion 0.097 Body portion 0.097 No.6
Head portion 0.095 No.18
Head portion 0.097 Body portion 0.094 Body portion 0.096 No.7
Head portion 0.096 No.19
Head portion 0.095 Body portion 0.097 Body portion 0.096 No.8
Head portion 0.094 No.20
Head portion 0.098 Body portion 0.096 Body portion 0.099 No.9
Head portion 0.096 No.21
Head portion 0.097 Body portion 0.096 Body portion 0.099 No.10
Head portion 0.098 No.22
Head portion 0.097 Body portion 0.096 Body portion 0.097 No.11
Head portion 0.101 No.23
Head portion 0.096 Body portion 0.099 Body portion 0.097 No.12
Head portion 0.096 Body portion 0.095

^{(Unit: Gy)}

Table 4 shows the results according to Example 2.

Referring to Table 4, the average absorbed dose of the mice (No. 1 to No. 5) on the 5th level was 0.0959 Gy, and the average absorption of the mice (No. 6 to No. 10) The average absorbed dose of mice (No.11 to No.15) at 0.0969 Gy and the average absorbed dose of mice (No.16 to No.20) at 2 levels were 0.0959 Gy, 0.0971 Gy, and the average absorbed dose of 0.097 Gy of mice (No.21 ~ No.23) on the 1st level were measured, and it was confirmed that the difference of average dose per level was not large.

In addition, it was confirmed that the error range of the average dose of each case with respect to the average dose of the entire case was less than 0 to ± 3%. As a result, a certain amount of dose was absorbed Respectively.

Therefore, it was confirmed that the radiation in the irradiation apparatus was irradiated in the same or similar manner to each mouse provided on the unit shelf.

One) The result according to Comparative Example 2

Table 5 shows the results of Comparative Example 1, and Table 5 shows the results.

Mouse number Irradiation site Absorbed dose Mouse number Irradiation site Absorbed dose No.1
Head portion 0.095 No.11
Head portion 0.101 Body portion 0.087 Body portion 0.110 No.2
Head portion 0.083 No.12
Head portion 0.115 Body portion 0.090 Body portion 0.107 No.3
Head portion 0.094 No.13
Head portion 0.092 Body portion 0.097 Body portion 0.092 No.4
Head portion 0.107 No.14
Head portion 0.074 Body portion 0.110 Body portion 0.072 No.5
Head portion 0.097 No.15
Head portion 0.058 Body portion 0.090 Body portion 0.067 No.6
Head portion 0.108 No.16
Head portion 0.070 Body portion 0.112 Body portion 0.057 No.7
Head portion 01092 No.17
Head portion 0.070 Body portion 0.094 Body portion 0.063 No.8
Head portion 0.094 No.18
Head portion 0.062 Body portion 0.091 Body portion 0.069 No.9
Head portion 0.092 No.19
Head portion 0.063 Body portion 0.082 Body portion 0.068 No.10
Head portion 0.086 No.20
Head portion 0.074 Body portion 0.095 Body portion 0.061

^{(Unit: Gy)}

Referring to Table 5, the average absorbed dose of the mice (No.1 to No.8) on the 4th level was 0.0961 Gy, and the average absorption of the mice (No. 9 to No. 13) The average dose of 0.097 Gy for the dose and 0.066 Gy for the mice (No.14 ~ No. 20) on the 1st level were measured. It was confirmed that the error range by level was considerably large, and that the mice on the 1st level absorbed a relatively small dose.

In particular, when the absorbed doses of mice housed in three housings are checked, it is confirmed that there is a large difference in absorbed dose between irradiated sites. It is confirmed that the dose absorbed by the mouse on the rear side is relatively small because the mice in one case are routed and overlapped with each other. Therefore, the range of average dose per mouse was less than 0 ~ ± 34%, which is a large error range compared to the average mouse dose.

The embodiments of the present invention described above and shown in the drawings should not be construed as limiting the technical idea of the present invention. The scope of protection of the present invention is limited only by the matters described in the claims, and those skilled in the art will be able to modify the technical idea of the present invention in various forms. Accordingly, such improvements and modifications will fall within the scope of the present invention as long as they are obvious to those skilled in the art.

110 ... ... The irradiation apparatus 200, 300 ... ... Research Center
262 ... ... Fixing groove 322 ... ... Guide groove
260, 360, 400 ... ... Housing case

Claims (9)

A plurality of unit shelves stacked in a vertical direction; And
A side part fixing the unit shelves;
Lt; / RTI >
The unit shelf is formed so that the radiation irradiated from the irradiation device can be uniformly irradiated to all the accommodating cases provided in the unit shelf,
Wherein the unit shelf is fitted in a guide groove for a unit shelf formed inside the side portion and is slidable in the forward and backward directions,
Wherein a unitary shelf is provided with a fixing protrusion on an upper surface thereof, a fixing groove is formed in a bottom surface extending portion of the containing case, and a fixing groove is fitted in the fixing protrusion to fix the containing case. delete delete The method according to claim 1,
Wherein the fixing groove is formed in an arc shape. The method according to claim 1,
The receiving case
A base plate on which the fixing groove is formed;
A body on which an animal is carried on the base plate to form a receiving space;
An opening / closing unit provided to one side of the body so that the animal can be loaded and unloaded;
A receiving part provided on the upper part of the body, wherein a part of the receiving part is inserted into the receiving space and the feed is embedded; And
A fixing member protruding outward from one side of the body so that a water bottle can be installed on one side of the body;
The irradiation surface of the irradiation apparatus including the irradiation surface. 6. The method of claim 5,
Further comprising at least one feed port for feeding the feed contained in the receiving section. 6. The method of claim 5,
Wherein the water reservoir mounted on the fixing member is provided with an irradiation unit for irradiating the animal through the opening formed on one side of the body. 6. The method of claim 5,
Wherein the receiving case is made of a transparent material. A plurality of unit shelves stacked in a vertical direction; And
A side part fixing the unit shelves;
And a guide groove formed on an upper surface of the unit shelf and in which a bottom guide of the housing case is fitted,
The radiation irradiated from the irradiation device is formed so as to be uniformly irradiated to the containing case according to the positional adjustment of the containing case,
Wherein the unit shelf is fitted in a guide groove for a unit shelf formed inside the side portion and is slidable in the forward and backward directions,
Wherein a unitary shelf is provided with a fixing protrusion on an upper surface thereof, a fixing groove is formed in a bottom surface extending portion of the containing case, and a fixing groove is fitted in the fixing protrusion to fix the containing case.

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