KR101322464B1 - Bio sensor and measuring device - Google Patents

Abstract

Disclosed are a bio sensor which reduces contamination caused by impurities and a measuring device. The present invention comprises: a protruded bar which equips with a sensor unit, which generates response signals of samples flowed in, at one end part; a side part frame which is connected to one end of the protruded bar and extended along the longitudinal direction of the protruded bar; and a sealing material which surrounds the protruded bar and the side part frame. If one side of the protruded bar is compressed, the side part frame is bent and the sensor unit of the protruded bar tears the sealing material and is exposed to outside.

Description

Bio sensor and measuring device {BIO SENSOR AND MEASURING DEVICE}

The present invention relates to a biosensor and a measuring device, and more particularly, to an individually packaged biosensor to improve safety and convenience.

Bio sensor refers to a means of investigating the properties of a substance by using a function of a living organism. Since a bio substance such as blood sugar or ketone is used as a detection device, it has excellent sensitivity and reaction specificity. Therefore, it is used in a wide range of fields such as clinical chemical analysis in the medical / medical field, process measurement in the bio industry, environmental measurement, and stability evaluation of chemicals. In particular, biosensors are widely used for various self tests such as blood glucose measurement, pregnancy diagnosis, urine test, and rapid disease diagnosis. The most common electrochemical biosensor is mainly used to measure blood glucose. An electrochemical reaction occurs when a sample such as blood is introduced into the biosensor, and an electrical signal is generated and transmitted to a measuring instrument connected to or connected to the biosensor. That's the way.

Such biosensors are usually packaged in a plurality of storage containers or individually wrapped in wrapping paper, so that the user takes out one by one and analyzes and mounts the measuring device. However, the biosensor packaged in this manner has a problem that the user takes out one by one by hand and is contaminated by his or her hand while mounting it on the measuring device.

SUMMARY OF THE INVENTION An object of the present invention devised in view of the above is to provide a biosensor and a measuring device capable of reducing contamination caused by impurities during mounting a biosensor to a measuring device.

In addition, an object of the present invention is to provide a biosensor and a measuring device that is made of a structure that is easy to laminate on the measuring device, and is configured to be removed after the measurement is completed by its own elastic force to improve the ease of use.

Bio-sensor and measuring device for achieving the object of the present invention as described above is a protruding bar provided at one end of the sensor unit for generating a reaction signal of the incoming sample; A side frame connected to the other end of the protruding bar and extending along the longitudinal direction of the protruding bar; And a sealing material surrounding the protruding bar and the side frame. Including, the side frame is bent by pressing the other side of the protruding bar while the sensor portion of the protruding bar tears the sealing material and is exposed to the outside.

In addition, more preferably, the side frames are formed at both ends of the rear end frame extending laterally from the other end of the protruding bar, and the other end of the side frame is connected to each other by a front end frame.

In addition, more preferably, the side frame is made of an elastic material.

In addition, more preferably, a bent groove is provided in the middle region of the side frame.

In addition, more preferably, one end of the protruding portion is provided with an inclined surface, the inclined surface in contact with the inclined surface is provided with an inclined surface inclined in the same direction as the inclined surface.

Also, more preferably, a lancet is mounted at the end of the protruding bar.

More preferably, a lancet is mounted on the outside of the tip frame.

More preferably, the sensor unit may include a spacer and a cover layer arranged side by side at intervals such that a reference electrode and a reaction electrode are stacked on each signal transmission electrode and an insulator, and a suction flow path is formed thereon. It is laminated.

Measuring device for achieving the object of the present invention as described above is a biosensor; A main body provided with a mounting portion on which at least one biosensor is installed; A pressing member which presses one end of the biosensor to bend the side frame and simultaneously expose the sensor unit of the protruding bar to the outside; A door installed at the front end of the mounting part of the main body to restrict access of the biosensor; A measurement circuit unit configured to measure a concentration of a target substance based on a reaction generated in the sensor unit by sample introduction; And a display unit which displays a measurement result of the measurement circuit unit.

As described above, the biosensor according to the present invention can reduce the contamination of the biosensor by impurities during the measurement, thereby improving the reliability of the measured value.

In addition, the biosensor and the measuring device according to the present invention have an effect of increasing convenience of packaging because the biosensor can be easily stacked, and the efficiency of packaging is increased, and since the biosensor and the measuring device can be removed using their own elastic force after being inserted into the measuring device and the measurement is completed. have.

In addition, the biosensor and the measuring device according to the present invention have the effect of preventing the surrounding contamination by the measurement sample since the protrusion of the biosensor is introduced into the sealing material by the elastic force after the measuring operation is completed and removed from the measuring device. .

1 is a perspective view showing a biosensor as a first preferred embodiment of the present invention;
2 is a state diagram showing a state in which the biosensor is pressed;
3 is a cross-sectional view showing a state in which protrusions of a biosensor are packaged;
4 is a cross-sectional view showing a state in which the protrusion of the biosensor is pulled out;
5 is a cross-sectional view showing a state in which a biosensor is installed in a measuring device;
6 is a cross-sectional view showing a state in which the biosensor is withdrawn from the measuring device,
7 is a perspective view illustrating a sensor unit of a biosensor;
8 is a cross-sectional view showing a biosensor as a second preferred embodiment of the present invention;
9 is a sectional view showing a biosensor as a third preferred embodiment of the present invention.

Hereinafter, with reference to the accompanying drawings, a biosensor and a measuring device which is a preferred embodiment of the present invention will be described in detail as follows.

1 is a perspective view illustrating a biosensor according to a first embodiment of the present invention, FIG. 2 is a state diagram showing a pressurized state of the biosensor, and FIG. 3 is a cross-sectional view showing a protrusion of the biosensor packaged. 4 is a cross-sectional view illustrating a state in which the protrusion of the biosensor is drawn out, FIG. 5 is a cross-sectional view illustrating a state in which the biosensor is installed in the measuring device, and FIG. 6 is a state in which the biosensor is drawn out of the measuring device. 7 is a perspective view illustrating a sensor unit of a biosensor, FIG. 8 is a cross-sectional view showing a biosensor as a second preferred embodiment of the present invention, and FIG. 9 is a biosensor as a third preferred embodiment of the present invention. One cross section.

As shown in FIGS. 1 to 7, the biosensor 1 according to the first embodiment of the present invention has a structure inserted into a mounting part formed in the measuring device 50. In this case, the biosensor 1 may have a structure stacked in a storage space formed inside the measuring device 50.

The biosensor 1 has a structure in which a protruding bar 21 is positioned inside a frame forming a frame shape and sealed with a sealing material 30. Frame is preferably made of a rectangular frame shape as shown, if the frame is a trapezoidal shape, or a shape in which the protrusion bar 21 can be inserted into the triangle or the like depending on the use environment may be made of any shape other than square. Irrelevant

The biosensor 1 has a rectangular frame shape consisting of a side frame 22 extending in the same direction at both ends of the rear end frame 23 and a front end frame 24 connecting the ends of the side frame 22 to each other. Is done.

A protruding bar 21 extending along the longitudinal direction of the side frame 22 is formed in the inner middle region of the rear end frame 23, and a sensor unit 10 is formed on the upper end of the protruding bar 21. do.

The sensor unit 10 is composed of a reaction layer and a cover layer. The reaction layer is preferably made of PCB or FPCB. In the reaction layer, the reference electrode 14 and the working electrode 16 are arranged on top of the signal transmission electrode 11 and the insulator 12 stacked thereon. The spacer 15, which is formed of a hot melt film, is stacked side by side at a predetermined interval on the reference electrode 14 and the working electrode 16. A cover layer 16 forming a cover layer is stacked on top of the spacers 15 arranged side by side at a predetermined interval. The cover layer 16 may be made of polycarbonate (PC), polyethylene (PET), film, or the like. It is preferable to use a PC that is softer than PET and is less likely to cause cracks at the corners when cutting. In addition, it is preferable that the transparent material is made so that the sample suction process can be confirmed. Spaces between the spacers 15 arranged side by side form a suction passage. In the suction passage, it is preferable that an air outlet communicating with the outside is formed so as to smoothly inhale the sample.

The reaction layer constituting the sensor unit 10 is preferably implemented by FPCB. After applying the reagent to each reaction electrode in the FPCB disc formed with electrodes on both sides, the hot melt film is raised, and the cover layer 16 is laminated thereon, and then bonded by heat fusion. When the bonding is completed by cutting for each reaction site to complete each sensor unit 10. Each sensor unit 10 preferably has a size of 1 to 3 mm in width, 2 to 5 mm in length, and 0.1 to 0.7 mm in thickness.

It is preferable that the bending groove 25 recessed to a predetermined depth is formed in the middle of the side frame 22 so that the side frame 22 can be bent smoothly. The bending groove 25 is preferably formed inside the side frame 22.

The sealing material 30 is mounted on the top and bottom surfaces of the frame consisting of the rear end frame 23, the side frame 22, and the front end frame 24. The sealing material 30 is preferably formed of a thin film material of a component that can block light and moisture, such as a foil, and does not affect the sensor unit 10. It is preferable that the inside of the sealing material 30 is sealed with a moisture proof material contained therein. Alternatively, the sealing material 30 may include a moisture proof component.

An inclined surface 21a is formed at one end surface of the protrusion 21. In addition, a rising surface 24a inclined in the same direction as the direction in which the inclined surface 21a is inclined is formed inside the tip frame 24 in contact with the inclined surface 21a.

As shown in FIG. 2, when the rear end frame 23 side of the biosensor 1 configured as described above is pressed, the end of the protruding bar 21 protrudes while the side frame 22 is bent. Referring to the process in which the protruding bar 21 protrudes in more detail, as shown in FIG. In this state, when the rear end frame 23 is pressed and the side frame 22 is bent, as shown in FIG. 4, the protruding bar 21 is advanced toward the front end frame 24, and the inclined surface 21a is raised. The protruding bar 21 is raised while contacting the 24a. As the sealing material 30 is torn by the rising protrusion bar 21, the protrusion bar 21 protrudes to the outside. The measurement operation is performed by the biosensor 1 mounted on the measuring device while the protrusion bar 21 penetrates the sealing material 30 and is exposed to the outside.

As shown in FIG. 5 and FIG. 6, when the measurement operation is performed in a state in which a plurality of biosensors 1 are stacked in a storage space formed inside the measuring device 50, at least the inside of the measuring device 50 may be disposed. One biosensor 1 is mounted. The biosensor 1 stored in the storage space operates the pressing member 51 to press the rear end frame 23 side of the biosensor 1.

When the rear end frame 23 presses the pressing member 51 while the front end frame 24 of the biosensor 1 is supported by the door 53 of the measuring device, the side frame 22 is bent and elastic. Is deformed. At this time, the side frame 22 is preferably made of an elastic material. When the force is applied due to the characteristics of the elastic material, the side frame 22 is bent and then returned to its original state where the force is removed.

At the same time as the side frame 22 is bent, the protruding bar 21 moves forward and is exposed to the outside through the sealing material 33. The sample may be sucked into the sensor unit 10 formed in the protrusion bar 21 exposed to the outside. In this case, the sensor unit 10 is in contact with the connecting element of the measuring device and is electrically connected to the measuring circuit unit of the measuring device 50. Thereafter, the measurement and analysis (quantitative or quantitative analysis) step of the biosensor 1 is performed. When a sample is introduced into the sensor unit 10, an electrochemical reaction is generated, and based on the reaction, the measurement circuit unit is a target substance in the sample. The concentration of is measured. The measurement result may be displayed on the display unit of the measuring device 50 or output by an output unit such as an internal or external printer or a speaker. The measuring device is provided with a display unit for displaying the measurement results. In addition, the measuring device is electrically connected to the sensor unit 10 is provided with a measuring circuit for performing the analysis.

After the measurement and analysis is completed, as shown in FIG. 6, the door 53 is opened and the pressing force applied to the side frame 22 is released. As the pressing force is released, the side frame 22 is returned to its original state by its elastic force, and is removed from the mounting portion of the measuring device 50 while being bounced off by the elastic force at this time.

Similarly, the biosensor 1 according to the second preferred embodiment of the present invention has a lancet 40 mounted to the outside of the tip frame 24 as shown in FIG. 8. The lancet 40 may be composed of a structure in which a separate protective cap is covered. The lancet 40 is a needle used to collect blood. Other structures and operation methods are the same as in the first preferred embodiment of the present invention.

Similarly, the biosensor 1 according to the third preferred embodiment of the present invention has a lancet 40 mounted at the tip end of the protruding bar 21 as shown in FIG. 9. In this case, since the lancet 40 maintains a sealed state inside the sealing material 30, the lancet 40 may be configured to have a separate cap to protect it. Other structures and operation methods are the same as in the first preferred embodiment of the present invention.

It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined in the appended claims and their equivalents. Of course, such modifications are within the scope of the claims.

1: biosensor 10: sensor unit
21: protrusion bar 22: side frame
23: rear end frame 24: front end frame
30: Seal material

Claims (9)

A protruding bar 21 having a sensor part 10 generating a reaction signal of an incoming sample at one end thereof;
A side frame 22 connected to the other end of the protruding bar 21 and extending along the longitudinal direction of the protruding bar 21; And
Including; sealer 30 surrounding the protruding bar 21 and the side frame 22,
Biosensor, characterized in that the side frame 22 is bent by pressing the other side of the protruding bar 21, the sensor unit 10 of the protruding bar 21 tears the sealing material 30 and exposed to the outside. . The method of claim 1,
The side frame 22 is formed at both ends of the rear end frame 23 extending laterally from the other end of the protruding bar 21, and the other end of the side frame 22 is a front end frame 24. Biosensor, characterized in that connected to each other by). The biosensor according to claim 2, wherein the side frame (22) is made of an elastic material. The biosensor according to claim 3, wherein a bending groove (25) is provided in an intermediate region of the side frame (22). The inclined surface 21a is provided at one end of the protruding bar 21, and the inclined surface 21a in contact with the inclined surface 21a is in the same direction as the inclined surface 21a. Biosensor, characterized in that the rising surface (24a) inclined in the direction. The biosensor according to claim 1, wherein a lancet (40) is mounted at the end of the protruding bar (21). The biosensor according to claim 2, wherein a lancet (40) is mounted on an outer side of the tip frame (24). The method of claim 1, wherein the sensor unit 10
The spacers are arranged side by side at intervals so that the reference electrode 13 and the reaction electrode 14 are stacked on each of the signal transmission electrodes 11 and the insulators 12 are stacked. 15) and the cover layer 16, characterized in that the biosensor is configured to be laminated. A biosensor (1) according to claim 1;
A main body 52 having a mounting portion on which at least one biosensor 1 is installed;
A pressing member 51 for pressing the one end of the biosensor 1 to bend the side frame 22 and to expose the sensor portion 10 of the protruding bar 21 to the outside;
A door (53) installed at the front end of the mounting portion of the main body (52) and restricting access of the biosensor (1);
A measurement circuit unit for measuring a concentration of a target substance based on a reaction generated in the sensor unit 10 by sample inflow; And
A display unit which displays a measurement result of the measurement circuit unit; Biosensor measuring apparatus comprising a.

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