KR100680271B1 - Wireless communication terminal for measurement of body information with temperature correction - Google Patents

Abstract

 The present invention relates to a wireless communication terminal for measuring biometric information having a temperature correction function. Specifically, when measuring biometric information using a wireless communication terminal, the temperature of the wireless communication terminal is different from the ambient temperature using the biosensor. Because of this inaccuracy, the present invention relates to a wireless communication terminal for measuring biological information having a temperature correction function for correcting biometric information measured at a wireless communication terminal using an ambient measurement temperature using the biosensor. The wireless communication terminal for measuring temperature information with temperature correction function measures temperature with a non-contact temperature sensor to correct the biometric information of the wireless communication terminal, so it is possible to accurately measure various biomaterial information affected by the measured temperature and is safe and costly. It is economical for less.

Temperature correction, biosensor, non-contact temperature sensor, biometric information measurement, strip sensor insert

Description

Wireless communication terminal for measurement of body information with temperature correction function {wireless communication terminal for measurement of body information with temperature correction}

1 is a front view of a wireless communication terminal incorporating a conventional blood glucose measurement apparatus.

2 is a front view of a wireless communication terminal for measuring biological information having a temperature correction function according to the present invention.

Figure 3 is a block diagram of a wireless communication terminal for measuring biological information having a temperature correction function according to the present invention.

4 is a flowchart of a wireless communication terminal for measuring biometric information having a temperature correction function according to the present invention.

<Description of the symbols for the main parts of the drawings>

1, 11: Biosensor 2, 12: Battery Pack

8, 18: main body of the wireless communication terminal 9, 19: display unit

10: wireless communication terminal equipped with a blood glucose measurement device

13: Non-contact temperature sensor 14: Container of biosensor

20: Wireless communication terminal for measuring biological information with temperature correction function

210: power supply unit 220: temperature measuring unit

230: strip sensor insert 240: current measurement circuit

250: signal conversion unit 260: microprocessor unit

270: memory unit 280: wireless communication terminal

The present invention relates to a wireless communication terminal for measuring biometric information having a temperature correction function. More specifically, the temperature of the wireless communication terminal when measuring biometric information using the wireless communication terminal is different from the ambient temperature using the biosensor. The present invention relates to a wireless communication terminal for measuring biometric information having a temperature correction function for correcting the biometric information of a wireless communication terminal using an ambient temperature using the biosensor.

The biosensor selectively detects and measures chemical substances (especially complex organic compounds) contained in a sample by using a biological detection function in which a living organism reacts sensitively to a specific substance such as an enzyme or an antibody, or a microorganism. A chemical sensor used to make a test, also known as a biochemical detector. In general, a detector used to selectively detect and measure chemical substances such as organic compounds contained in a sample is called a chemical sensor. This biosensor detects complex organic compounds that have been difficult to detect using non-biochemical chemical sensors. It is used to detect and measure.

The first mechanism of the biosensor is a semiconductor device that detects a specific component such as an enzyme or an antibody (immune) of a living organism or a specific kind of microorganism in a detection device, which is a sensing device, and converts a physical quantity into a voltage or current value. It consists of a transducer, an electrode, etc., and displays the quantity (concentration) of the specific chemical substance detected by the detection element as a value of voltage and current.

Biosensors are also classified into enzyme sensors, microbial sensors, and immunosensors according to the type of detection element. Currently, only the enzymatic sensors and microbial sensors are in practical use, and specificity only affects specific substrate molecules or reactions of enzyme proteins. Enzyme sensors using (molecules, reaction identification and selection functions) are most commonly used.

Examples of enzyme sensors already developed or currently in use include glucose sensors used to detect blood glucose levels and monitoring symptoms of diabetic patients, urea sensors used to control hemodialysis of artificial kidneys, and blood uric acid. As a concentration sensor, there is a uric acid sensor which is used to monitor symptoms of gout patients. In addition, a multi-functional enzyme sensor that simultaneously detects the concentration of two or more chemicals, such as a freshness sensor that determines the freshness of fish by measuring the concentration of three chemicals simultaneously, has also been developed.

Microbial sensors, which use living microorganisms as a detection element, are fixed and installed in membranes, etc., and are used for process control of fermentation industry such as alcohol fermentation and glutamic acid fermentation, and measurement of biological oxygen demand (BOD) which is an indicator of water pollution. On the other hand, biosensors using large organisms such as fish are being studied, although their sensitivity is lower than that of microbial sensors.

Immune sensors using antibodies as detectors are used to diagnose diseases. For example, recently, an immunosensor equipped with an antibody corresponding to a cancer-specific marker (marker) as a detection element has been developed, and this makes cancer diagnosis faster. It may also be used for early diagnosis of AIDS.

As a new trend in recent years, small semiconductor biosensors in which enzymes are formed on a small semiconductor chip in a thin film form have been developed. When this is put into practical use, the small semiconductor biosensors are put into living organisms and directly incorporated into the body such as blood components. Measurements will be made, and simultaneous measurement of multiple chemicals will be easier and faster.

The second mechanism of the biosensor is to spectroscopically irradiate the measurement object with a wavelength of a certain area, and then analyze the reflected wavelength and read the measurement object by comparing with a previously prepared data table. Here, the wavelength of the predetermined region is used differently depending on the type of the measurement object.

When measuring biometric information using the biosensor as described above, blood glucose level, cholesterol level, liver level are greatly affected by temperature. Therefore, it is necessary to correct the temperature for accurate measurement.

Among them, the blood glucose measurement according to the first mechanism has the following characteristics.

Many diabetics are measuring blood glucose daily because of extreme exercise, food, and complications. Accordingly, there are many types of blood glucose meters, and there are various types of blood glucose meters, ranging from medical devices that measure blood sugar levels to diabetes phones having blood sugar measuring devices embedded in wireless communication terminals.

1 is a front view of a wireless communication terminal equipped with a conventional blood glucose measurement apparatus.

As shown in FIG. 1, a biosensor 1 coated with an enzyme reacting with blood sugar is inserted into a biosensor injecting unit 5 of a battery pack 2 in a wireless communication terminal 10 equipped with a blood sugar measuring apparatus. Thereafter, the blood sugar is measured by the wireless communication terminal main body 8 and sent to the display unit 9 to display the blood sugar level.

In addition, a mobile phone equipped with a conventional blood glucose measurement apparatus is described in Korean Patent Laid-Open No. 2003-96652. The Korean Patent Laid-Open Publication No. 2003-96652 discloses injecting blood into a strip sensor after inserting the glucose-sensitive enzyme-coated strip sensor into a wireless communication terminal, or injecting blood into the strip-sensor-coated strip sensor. After inserting the strip sensor into the wireless communication terminal. Then, glucose and enzyme react on the strip sensor to generate electrons, which are detected by the current sensor. The current sensor senses the current flowing between the two terminals and converts the sensed current into a digital signal to fit the input of the mobile station modem (MSM). The digital signal is input to the mobile station modem, and the mobile station modem processes the input digital signal based on the data (current / voltage relationship according to the reagent code) already databased in the memory unit. The signal thus processed is displayed as a blood sugar level by a liquid crystal display (LCD) display unit.

However, in the wireless communication terminal equipped with the blood glucose measurement apparatus as described above, the reaction between glucose and the glucose-reacting enzyme is sensitively changed according to temperature, and thus the following problems occur.

First, since the temperature occurs in the wireless communication terminal itself, it is not possible to measure the exact blood glucose level by maintaining a constant temperature.

 Second, since the temperature at which glucose reacts with enzymes cannot be known accurately, accurate blood glucose levels cannot be measured.

Therefore, the inventors of the present invention measure the ambient temperature at which glucose reacts with the glucose-reacting enzyme and use the temperature to correct the blood glucose level measured by the wireless communication terminal to obtain accurate blood glucose levels, thereby promoting the health of many diabetics and the general public. The present invention has been completed by developing an apparatus and method for accurately measuring biological information affected by temperature, including blood sugar.

An object of the present invention is to measure the temperature at which glucose reacts with glucose-reacting enzymes, and to correct blood sugar levels measured by wireless communication terminals to obtain accurate blood sugar levels, thereby promoting the health of many diabetics and the general public, and The present invention provides a wireless communication terminal for measuring biological information having a temperature correction function for accurately measuring biological information affected by temperature.

The present invention provides a biosensor insertion unit for inserting a biosensor that directly detects biometric information of a subject, a means for measuring temperature, and biometric information input from the biosensor based on previously stored analyzer initial data. In the wireless communication terminal having a control unit for analyzing the bio-information inputted from the biosensor using the temperature measured by the temperature measuring means, wherein the temperature measuring means does not directly contact the object temperature of the object It provides a wireless communication terminal for measuring biological information having a temperature correction function, characterized in that for measuring.

Hereinafter, the present invention will be described in detail.

A wireless communication terminal for measuring temperature information having a temperature correction function according to the present invention is a non-contact temperature sensor that measures the temperature of the storage container of the biosensor to grasp the ambient temperature using the biosensor, and the blood glucose level and cholesterol level at this temperature. It is to correct the values of biological information affected by temperature such as liver and liver values to the correct value.

Here, the wireless communication terminal for measuring biological information having the temperature correction function,

As the biosensor, it may be formed by applying an enzyme such as glucose reactive enzyme, cholesterol reactive enzyme and hepatic metabolite reactive enzyme.

The glucose reactive enzyme may be glucose oxidase and glucose dehydrogenase.

The temperature measuring means may be a non-contact temperature sensor.

The non-contact temperature sensor may be an infrared temperature sensor.

In the case of correcting the cholesterol level, a wireless communication terminal for measuring biological information having a temperature correction function for correcting the blood glucose level can be used in the same manner except that the cholesterol measuring biosensor is used instead of the glucose measuring biosensor.

In the case of correcting the liver level, a wireless communication terminal for measuring biological information having a temperature correction function for correcting the blood glucose level can be used in the same manner except that the liver level measuring biosensor is used instead of the glucose measuring biosensor.

In addition, the biometric information measuring method using a wireless communication terminal for measuring biometric information having a temperature correction function according to the present invention is a non-contact temperature sensor provided in the wireless communication terminal by measuring the temperature of the biosensor storage container and the temperature of the enzyme reaction temperature It is adopted to correct the values in the data table with the enzyme reaction temperature to obtain accurate biometric information.

Here, the blood glucose measurement method using a wireless communication terminal for measuring biometrics having the temperature correction function,

The method may further include returning to the step of recognizing whether the biometric information measurement mode (blood glucose measurement mode) is selected after performing a general function of the wireless communication terminal when the biometric information measurement mode (blood glucose measurement mode) is not selected. have.

The amount of blood may be 1 μl to 10 μl.

Correcting the cholesterol level may be the same as the method of correcting the blood sugar level except using the cholesterol sensor instead of the glucose sensor.

When the liver level is corrected, it may be the same as the method for correcting the blood glucose level except using the liver level sensor instead of the glucose sensor.

Hereinafter, with reference to the accompanying drawings, preferred embodiments of a wireless communication terminal for measuring biological information and a biometric information measuring method having a temperature correction function according to the present invention will be described in detail.

2 is a front view of a wireless communication terminal for measuring biological information having a temperature correction function according to the present invention.

As shown in FIG. 2, the wireless communication terminal 20 equipped with a blood glucose, cholesterol, and liver measuring device for temperature correction measures the temperature of the biosensor container 14 by using a non-contact temperature sensor 13. The non-contact temperature sensor 13 is preferably an infrared sensor. For reference, the reason for measuring the temperature of the biosensor container 14 is to measure the room temperature of the environment around the terminal.

Then, the biosensor 11 is inserted into the biosensor insertion unit 15 in the battery pack 12. The body 19 of the wireless communication terminal corrects the biometric information of blood glucose, cholesterol, and liver metabolites measured by referring to the temperature of the biosensor container 14 and displays the numerical value on the display unit 19. This will be described in more detail below.

Figure 3 is a block diagram of a wireless communication terminal for measuring biological information having a temperature correction function according to the present invention.

As shown in FIG. 3, a power supply voltage is supplied to the biometric information measuring device using the wireless communication terminal through the power supply unit 210. At this time, the power supply unit 210 may obtain energy mainly through a battery.

In addition, the temperature measuring unit 220 is a non-contact temperature sensor, by measuring the temperature of the strip sensor vessel to obtain the room temperature measurement results of the surrounding environment.

In addition, the strip sensor, which is a biosensor with biometric information detection unit, is inserted into the wireless communication terminal through the strip sensor inserting unit 230.

In addition, the current measuring circuit unit 240 receives the power supply voltage, has two terminals, and detects a change in current according to the concentration of analyte between the two terminals.

In addition, the signal converter 250 (ADC) converts the sensed current into biometric information in digital form.

In this case, there is a method for detecting the biological information in addition to the electrochemical method, there is a spectroscopic method. In the spectroscopic method, a wavelength of a predetermined range is irradiated to a measurement object, and then the wavelength is reflected and analyzed to compare the data with a previously prepared data table to read the measurement object. Here, the wavelength of the predetermined region is used differently depending on the type of the measurement object.

In addition, the microprocessor unit 260 obtains concentration data corresponding to the digital form biometric information input from the signal conversion unit 250 from the data table and then uses the temperature measurement value obtained from the temperature measuring unit 220. After correcting the obtained concentration data, and displays on the display unit.

In addition, the memory unit 270 is controlled by the microprocessor unit 260 and stores a data table to which density data corresponding to the biometric information is mapped.

In addition, the wireless communication terminal 280 (display unit) receives the concentration data from the microprocessor unit and displays it.

4 is a flowchart of a wireless communication terminal for measuring biometric information having a temperature correction function according to the present invention.

As shown in FIG. 4, after the operation of the wireless communication terminal starts (S310), it may be recognized whether the measurement mode is S320. <Yes> is a blood glucose measurement mode, and <No> is a general function (S400) of the wireless communication terminal.

In addition, in the temperature measuring step (S330), the temperature of the container containing the strip sensor, that is, the ambient temperature, is measured by the non-contact temperature sensor.

In addition, in the step of inserting the strip sensor (S340), the strip sensor is inserted into the strip sensor insertion part of the wireless communication terminal.

In addition, in the blood injection step (S350), the blood is collected and injected into the strip sensor.

In addition, the current measurement step (S360) detects that a current is formed between the two terminals by the electrons generated by the reaction of glucose (blood sugar) and glucose oxidase.

In addition, in the signal processing step S370, the sensed current is converted into biometric information in digital form.

In addition, in the concentration correction step (S380), the concentration data corresponding to the biometric information converted into the digital form is acquired in the memory unit 270 and then corrected using the temperature of the strip sensor container, for example, the measured temperature. The difference between the reference temperature and the preset reference temperature is obtained, and if the difference has a positive value, the numerical value corresponding to the value is added to the obtained concentration data, and if the difference has a negative value, the value is obtained. The concentration data corresponding to the biometric information is corrected by subtracting the numerical value corresponding to the from the obtained concentration.

In addition, in the blood sugar value display step S390, the corrected concentration data is displayed on the display element.

In addition, the blood sugar measurement mode (S320) returns to the step of recognizing whether the blood sugar measurement mode is selected.

In addition, when the blood glucose measurement mode is not selected, the general function step S400 returns to a step of recognizing whether the blood glucose measurement mode is selected after performing a general function of the wireless communication terminal.

Cholesterol level and liver metabolite level are the same as the method of measuring and correcting the blood glucose level except using a cholesterol sensor and a liver metabolite sensor, that is, a change in the physical quantity current.

In the above description of the preferred embodiment of the present invention by way of example, the scope of the present invention is not limited to this particular embodiment, and those skilled in the art are appropriate within the scope described in the claims of the present invention. It will be possible to change.

The wireless communication terminal for measuring biometric information having a temperature correction function of the present invention measures temperature with a non-contact temperature sensor to correct biometric information measured at the wireless communication terminal, thereby accurately measuring various biological materials affected by the measurement temperature. Safe and low cost, economical.

Claims (4)

Biosensor insertion unit for inserting a biosensor that directly detects the biometric information of the subject, means for measuring the temperature, and biometrics information input from the biosensor based on the analyzer data stored in advance before the analysis In the wireless communication terminal having a control unit for correcting the biometric information input from the biosensor using the temperature measured by the temperature measuring means, And the temperature measuring means measures a temperature of the object without directly contacting the object.  The wireless communication terminal of claim 1, wherein the biosensor comprises glucose oxidase or glucose dehydrogenase. 2. The wireless communication terminal for measuring biological information according to claim 1, wherein the temperature measuring means is a non-contact temperature sensor.  The wireless communication terminal for measuring biometric information according to claim 3, wherein the non-contact temperature sensor is an infrared temperature sensor.

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