JPWO2020002177A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020002177A5
JPWO2020002177A5 JP2020572424A JP2020572424A JPWO2020002177A5 JP WO2020002177 A5 JPWO2020002177 A5 JP WO2020002177A5 JP 2020572424 A JP2020572424 A JP 2020572424A JP 2020572424 A JP2020572424 A JP 2020572424A JP WO2020002177 A5 JPWO2020002177 A5 JP WO2020002177A5
Authority
JP
Japan
Prior art keywords
catheter
patient
target area
needle
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020572424A
Other languages
Japanese (ja)
Other versions
JP2021529588A (en
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/066574 external-priority patent/WO2020002177A1/en
Publication of JP2021529588A publication Critical patent/JP2021529588A/en
Publication of JPWO2020002177A5 publication Critical patent/JPWO2020002177A5/ja
Pending legal-status Critical Current

Links

Claims (20)

カテーテルであって、
遠位部分及び近位部分、
前記カテーテルの前記遠位部分に配置され、血管構造の外部に配置されている対象者の軟組織内のロケーションをイメージングし、画像信号を生成するイメージング装置、並びに
前記カテーテルの前記遠位部分に配置された第1の出口ポートを備える第1のルーメンであって、ガイドワイヤを受け入れる第1のルーメン、
を備えるカテーテルと、
前記カテーテル内にスライド可能に配置された針であって、第2のルーメンおよび第2の出口ポートを備える針と、
前記画像信号を受信するためのコントローラと
を備える、血管内処置システムであって、
前記コントローラは、実行されると1つ又は複数のプロセッサに、
前記画像信号を使用して前記血管構造の外部に配置されている前記対象者の軟組織をイメージングすることと、
前記対象者の軟組織内の対象領域を識別することと、
前記針を前記カテーテルに対して並進させ、前記針を、前記血管構造を通じて前記対象領域へと挿入させることと、
前記針を通じて前記対象領域に治療薬を送達することと
を行わせる命令を含む、非一時的コンピュータ可読媒体を備える、
血管内処置システム。
It ’s a catheter,
Distal and proximal parts,
An imaging device that is located in the distal portion of the catheter and is located outside the vascular structure to image a location in the subject's soft tissue and generate an image signal, as well as in the distal portion of the catheter. A first lumen with a first exit port and a first lumen that accepts a guide wire.
With a catheter and
A needle slidably disposed within the catheter, comprising a second lumen and a second exit port.
An intravascular treatment system comprising a controller for receiving the image signal.
When the controller is executed, it becomes one or more processors.
Using the image signal to image the soft tissue of the subject located outside the vascular structure,
Identifying the target area within the subject's soft tissue and
The needle is translated with respect to the catheter and the needle is inserted into the target area through the vascular structure.
A non-temporary computer-readable medium comprising an instruction to deliver a therapeutic agent to the subject area through the needle.
Intravascular treatment system.
前記非一時的コンピュータ可読媒体の、前記対象領域を識別するための前記命令は、実行されると、1つ又は複数のプロセッサに、前記対象領域内の組織のタイプを決定することを行わせる命令を含む、請求項1に記載の血管内処置システム。 The instruction for identifying the area of interest on the non-temporary computer-readable medium, when executed, causes one or more processors to determine the type of tissue within the area of interest. The intravascular treatment system according to claim 1. 前記非一時的コンピュータ可読媒体の、前記対象領域を識別するための前記命令は、実行されると、1つ又は複数のプロセッサに、前記対象者の軟組織内の前記対象領域のロケーション又は位置を決定することを行わせる命令を含む、請求項1に記載の血管内処置システム。 When executed, the instruction for identifying the target area of the non-temporary computer-readable medium determines the location or location of the target area in the soft tissue of the subject to one or more processors. The intravascular treatment system of claim 1, comprising an instruction to do so. 前記対象領域の前記ロケーション又は位置は距離を含む、請求項3に記載の血管内処置システム。 The intravascular treatment system of claim 3, wherein the location or location of the subject area comprises a distance. 前記距離は前記対象者の軟組織の別の部分に対するものである、請求項4に記載の血管内処置システム。 The intravascular treatment system of claim 4, wherein the distance is to another portion of the subject's soft tissue. 前記非一時的コンピュータ可読媒体の、前記対象領域を識別するための前記命令は、実行されると、1つ又は複数のプロセッサに、前記対象領域のサイズを識別することを行わせる命令を含む、請求項1に記載の血管内処置システム。 The instructions for identifying the target area of the non-temporary computer-readable medium include instructions that, when executed, cause one or more processors to identify the size of the target area. The intravascular treatment system according to claim 1. 前記非一時的コンピュータ可読媒体の、前記対象領域を識別するための前記命令は、実行されると、1つ又は複数のプロセッサに、前記対象領域の密度を識別することを行わせる命令を含む、請求項1に記載の血管内処置システム。 The instructions for identifying the target area of the non-temporary computer-readable medium include instructions that, when executed, cause one or more processors to identify the density of the target area. The intravascular treatment system according to claim 1. 前記針を通じて前記対象領域に前記治療薬を送達するための前記命令は、実行されると、1つ又は複数のプロセッサに、前記対象領域のサイズ及び前記対象領域の密度のうちの少なくとも1つに基づく量の治療薬を送達することを行わせる命令を含む、請求項1に記載の血管内処置システム。 The instruction to deliver the therapeutic agent to the subject area through the needle, when executed, to one or more processors, to at least one of the size of the subject area and the density of the subject area. The intravascular treatment system according to claim 1, comprising an instruction to deliver a therapeutic agent in a base amount. 前記画像信号は、500キロヘルツ(KHz)~30メガヘルツ(MHz)の間のエネルギーを生成するトランスデューサから生成される、請求項1に記載の血管内処置システム。 The intravascular treatment system of claim 1, wherein the image signal is generated from a transducer that produces energy between 500 kHz (KHz) and 30 MHz (MHz). 前記針は、前記カテーテルの前記第1のルーメンの少なくとも一部分に実質的に平行である、請求項1に記載の血管内処置システム。 The intravascular treatment system of claim 1, wherein the needle is substantially parallel to at least a portion of the first lumen of the catheter. 患者を処置する方法であって、前記患者は、皮膚の下且つ血管構造の外部に配置されている組織を含み、前記方法は、
カテーテルを提供するステップであって、前記カテーテルは、
遠位部分及び近位部分、
前記カテーテルの前記遠位部分に配置され、前記血管構造の外部に配置されている前記患者の軟組織内のロケーションをイメージングし、画像信号を生成するイメージング装置、並びに
前記カテーテルの前記遠位部に配置された第1の出口ポートを備える第1のルーメンであって、ガイドワイヤを受け入れる第1のルーメン、
を有する、ステップと、
前記カテーテル内でスライド可能に、且つ、前記カテーテルの前記第1のルーメンの少なくとも一部分に実質的に平行に、第2のルーメン及び第2の出口ポートを備える針を供給するステップと、
前記画像信号を使用して血管構造の外部に配置されている前記患者の軟組織をイメージングするステップと、
前記患者の軟組織内の対象領域を識別するステップと、
前記針を前記カテーテルに対して並進させ、前記針を、前記血管構造を通じて前記対象領域へと挿入するステップと、
前記針を通じて前記対象領域に治療薬を送達するステップと
を含む、患者を処置する方法。
A method of treating a patient, wherein the patient comprises tissue located under the skin and outside the vascular structure.
A step of providing a catheter, wherein the catheter is
Distal and proximal parts,
An imaging device located in the distal portion of the catheter and located outside the vascular structure in the soft tissue of the patient to generate an image signal, as well as in the distal portion of the catheter. A first rumen with a placed first exit port, a first rumen that accepts a guide wire.
Have, step and,
A step of supplying a needle with a second lumen and a second exit port that is slidable within the catheter and substantially parallel to at least a portion of the first lumen of the catheter.
The step of imaging the patient's soft tissue located outside the vascular structure using the image signal,
The step of identifying the target area in the patient's soft tissue,
A step of translating the needle with respect to the catheter and inserting the needle into the target area through the vascular structure.
A method of treating a patient, comprising delivering a therapeutic agent to the subject area through the needle.
前記対象領域を識別するステップは、前記対象領域内の組織のタイプを決定するステップを含む、請求項11に記載の患者を処置する方法。 The method of treating a patient according to claim 11, wherein the step of identifying the subject area comprises the step of determining the type of tissue within the subject area. 前記対象領域を識別するステップは、前記患者の軟組織内の前記対象領域のロケーション又は位置を決定するステップを含む、請求項11に記載の患者を処置する方法。 11. The method of treating a patient, wherein the step of identifying the subject area comprises the step of determining the location or location of the subject area within the soft tissue of the patient. 前記対象領域の前記ロケーション又は位置は距離を含む、請求項13に記載の患者を処置する方法。 13. The method of treating a patient according to claim 13, wherein the location or location of the subject area comprises a distance. 前記距離は前記患者の軟組織の別の部分に対するものである、請求項14に記載の患者を処置する方法。 The method of treating a patient according to claim 14, wherein the distance is relative to another portion of the patient's soft tissue. 前記対象領域を識別するステップは、前記対象領域のサイズを識別するステップを含む、請求項11に記載の患者を処置する方法。 The method of treating a patient according to claim 11, wherein the step of identifying the target area comprises a step of identifying the size of the target area. 前記対象領域を識別するステップは、前記対象領域の密度を識別するステップを含む、請求項11に記載の患者を処置する方法。 The method of treating a patient according to claim 11, wherein the step of identifying the target area includes a step of identifying the density of the target area. 前記針を通じて前記対象領域に前記治療薬を送達するステップは、前記対象領域のサイズ及び前記対象領域の密度のうちの少なくとも1つに基づく量の治療薬を送達するステップを含む、請求項11に記載の患者を処置する方法。 11. The step of delivering the therapeutic agent to the subject area through the needle comprises delivering an amount of the therapeutic agent based on at least one of the size of the target area and the density of the target area. How to treat the described patients. 前記イメージング装置は、500キロヘルツ(KHz)~30メガヘルツ(MHz)の間のエネルギーを生成するトランスデューサである、請求項11に記載の患者を処置する方法。 The method of treating a patient according to claim 11, wherein the imaging device is a transducer that produces energy between 500 kilohertz (KHz) and 30 megahertz (MHz). 前記針は、前記カテーテルの前記第1のルーメンの少なくとも一部分に実質的に平行である、請求項11に記載の患者を処置する方法。 11. The method of treating a patient, wherein the needle is substantially parallel to at least a portion of the first lumen of the catheter.
JP2020572424A 2018-06-28 2019-06-24 Local delivery of internally ultrasound-assisted therapeutic agents Pending JP2021529588A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862691535P 2018-06-28 2018-06-28
US62/691,535 2018-06-28
PCT/EP2019/066574 WO2020002177A1 (en) 2018-06-28 2019-06-24 Internal ultrasound assisted local therapeutic delivery

Publications (2)

Publication Number Publication Date
JP2021529588A JP2021529588A (en) 2021-11-04
JPWO2020002177A5 true JPWO2020002177A5 (en) 2022-07-01

Family

ID=67003513

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020572424A Pending JP2021529588A (en) 2018-06-28 2019-06-24 Local delivery of internally ultrasound-assisted therapeutic agents

Country Status (5)

Country Link
US (1) US20200000525A1 (en)
EP (1) EP3813674A1 (en)
JP (1) JP2021529588A (en)
CN (1) CN112584774A (en)
WO (1) WO2020002177A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD834182S1 (en) * 2017-06-20 2018-11-20 Genesis Cosmetics LLC Syringe
USD913940S1 (en) * 2018-04-12 2021-03-23 Hamamatsu Photonics K.K. Electrode for X-ray tube
USD937414S1 (en) * 2019-03-12 2021-11-30 Neurescue Aps Reboa catheter tip
USD896373S1 (en) * 2019-06-27 2020-09-15 Karl Storz Endovision, Inc. Cystoscope distal tip
USD896374S1 (en) * 2019-06-27 2020-09-15 Karl Storz Endovision, Inc. Cystoscope distal tip
CN214956033U (en) * 2020-03-19 2021-11-30 巴德阿克塞斯系统股份有限公司 Data acquisition module, data acquisition equipment and medical device monitoring system
US20220079684A1 (en) * 2020-09-14 2022-03-17 Jaiben GEORGE Medical device for guiding a surgical instrument
JPWO2022202302A1 (en) * 2021-03-24 2022-09-29
WO2022202303A1 (en) * 2021-03-25 2022-09-29 テルモ株式会社 Computer program, information processing method, and information processing device
WO2022235980A1 (en) * 2021-05-05 2022-11-10 Acoustiic Inc. Event-based ultrasound system
WO2023136140A1 (en) * 2022-01-13 2023-07-20 朝日インテック株式会社 Catheter
US11779362B1 (en) * 2022-08-01 2023-10-10 Truvue, Inc. Methods and apparatus for true lumen re-entry

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794931A (en) 1986-02-28 1989-01-03 Cardiovascular Imaging Systems, Inc. Catheter apparatus, system and method for intravascular two-dimensional ultrasonography
US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
US4841977A (en) 1987-05-26 1989-06-27 Inter Therapy, Inc. Ultra-thin acoustic transducer and balloon catheter using same in imaging array subassembly
US4917097A (en) 1987-10-27 1990-04-17 Endosonics Corporation Apparatus and method for imaging small cavities
US4951677A (en) 1988-03-21 1990-08-28 Prutech Research And Development Partnership Ii Acoustic imaging catheter and the like
NL8902559A (en) 1989-10-16 1991-05-16 Du Med Bv INTRA-LUMINAL DEVICE.
US5240003A (en) 1989-10-16 1993-08-31 Du-Med B.V. Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board
US5095911A (en) 1990-05-18 1992-03-17 Cardiovascular Imaging Systems, Inc. Guidewire with imaging capability
US5135486A (en) 1990-08-31 1992-08-04 Endosonics Corporation Self-venting balloon dilitation catheter
US5167233A (en) 1991-01-07 1992-12-01 Endosonics Corporation Dilating and imaging apparatus
US5353798A (en) 1991-03-13 1994-10-11 Scimed Life Systems, Incorporated Intravascular imaging apparatus and methods for use and manufacture
US5243988A (en) 1991-03-13 1993-09-14 Scimed Life Systems, Inc. Intravascular imaging apparatus and methods for use and manufacture
US6134003A (en) 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
JP3479069B2 (en) 1991-04-29 2003-12-15 マサチューセッツ・インステチュート・オブ・テクノロジー Method and apparatus for optical imaging and measurement
US6111645A (en) 1991-04-29 2000-08-29 Massachusetts Institute Of Technology Grating based phase control optical delay line
US5183048A (en) 1991-06-24 1993-02-02 Endosonics Corporation Method and apparatus for removing artifacts from an ultrasonically generated image of a small cavity
US5373845A (en) 1992-05-22 1994-12-20 Echo Cath, Ltd. Apparatus and method for forward looking volume imaging
US5373849A (en) 1993-01-19 1994-12-20 Cardiovascular Imaging Systems, Inc. Forward viewing imaging catheter
US5368037A (en) 1993-02-01 1994-11-29 Endosonics Corporation Ultrasound catheter
US5453575A (en) 1993-02-01 1995-09-26 Endosonics Corporation Apparatus and method for detecting blood flow in intravascular ultrasonic imaging
US5921931A (en) 1997-04-08 1999-07-13 Endosonics Corporation Method and apparatus for creating a color blood flow image based upon ultrasonic echo signals received by an intravascular ultrasound imaging probe
EP1059878B1 (en) 1998-03-05 2005-11-09 Gil M. Vardi Optical-acoustic imaging device
US6200268B1 (en) 1999-09-10 2001-03-13 The Cleveland Clinic Foundation Vascular plaque characterization
US6554801B1 (en) * 2000-10-26 2003-04-29 Advanced Cardiovascular Systems, Inc. Directional needle injection drug delivery device and method of use
US6645195B1 (en) * 2001-01-05 2003-11-11 Advanced Cardiovascular Systems, Inc. Intraventricularly guided agent delivery system and method of use
ES2246999T3 (en) * 2001-11-23 2006-03-01 Nucletron B.V. AUTOCONTROLLED DEVICE GUIDED BY IMAGES TO INSERT A NEEDLE IN THE BODY OF AN ANIMAL TO PERFORM RADIOTHERAPY IN THIS BODY.
US7074188B2 (en) 2002-08-26 2006-07-11 The Cleveland Clinic Foundation System and method of characterizing vascular tissue
US6943881B2 (en) 2003-06-04 2005-09-13 Tomophase Corporation Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
EP2278266A3 (en) 2004-11-24 2011-06-29 The General Hospital Corporation Common-Path Interferometer for Endoscopic OCT
EP1887946A2 (en) 2005-06-06 2008-02-20 The Board Of Regents, The University Of Texas System Oct using spectrally resolved bandwidth
JP2008543511A (en) 2005-06-24 2008-12-04 ヴォルケイノウ・コーポレーション Vascular image preparation method
CN101287403B (en) * 2005-09-22 2011-06-15 康图拉公司 Probe for insertion in the anal canal
US8449465B2 (en) 2005-10-14 2013-05-28 Cleveland Clinic Foundation System and method for characterizing vascular tissue
WO2007047974A2 (en) 2005-10-20 2007-04-26 Board Of Regents, The University Of Texas System Rotating optical catheter tip for optical coherence tomography
US8125648B2 (en) 2006-06-05 2012-02-28 Board Of Regents, The University Of Texas System Polarization-sensitive spectral interferometry
US20080097476A1 (en) * 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies
US8108030B2 (en) 2006-10-20 2012-01-31 Board Of Regents, The University Of Texas System Method and apparatus to identify vulnerable plaques with thermal wave imaging of heated nanoparticles
WO2008091961A2 (en) 2007-01-23 2008-07-31 Volcano Corporation Optical coherence tomography implementation
US8781193B2 (en) 2007-03-08 2014-07-15 Sync-Rx, Ltd. Automatic quantitative vessel analysis
WO2009009802A1 (en) 2007-07-12 2009-01-15 Volcano Corporation Oct-ivus catheter for concurrent luminal imaging
EP2191227A4 (en) 2007-08-10 2017-04-19 Board of Regents, The University of Texas System Forward-imaging optical coherence tomography (oct) systems and probe
US7787127B2 (en) 2007-10-15 2010-08-31 Michael Galle System and method to determine chromatic dispersion in short lengths of waveguides using a common path interferometer
US7813609B2 (en) 2007-11-12 2010-10-12 Lightlab Imaging, Inc. Imaging catheter with integrated reference reflector
US9974509B2 (en) 2008-11-18 2018-05-22 Sync-Rx Ltd. Image super enhancement
US8187191B2 (en) 2009-01-08 2012-05-29 Volcano Corporation System and method for equalizing received intravascular ultrasound echo signals
US10058284B2 (en) * 2012-12-21 2018-08-28 Volcano Corporation Simultaneous imaging, monitoring, and therapy
WO2015074045A2 (en) * 2013-11-18 2015-05-21 Jeremy Stigall Therapeutic delivery catheter with imaging and tissue characterization
US11890025B2 (en) * 2013-11-18 2024-02-06 Philips Image Guided Therapy Corporation Guided thrombus dispersal catheter
US20160374710A1 (en) * 2014-03-12 2016-12-29 Yegor D. Sinelnikov Carotid body ablation with a transvenous ultrasound imaging and ablation catheter
US20150289750A1 (en) * 2014-04-11 2015-10-15 Jeremy Stigall Imaging and treatment device
WO2016009337A2 (en) * 2014-07-15 2016-01-21 Koninklijke Philips N.V. Devices and methods for intrahepatic shunts
CN107072693B (en) * 2014-09-15 2021-03-12 伊西康公司 System for targeted delivery of therapeutic agents to tissue
EP3285653B1 (en) * 2015-04-20 2019-12-18 Koninklijke Philips N.V. Dual lumen diagnostic catheter
CN107582109B (en) * 2017-10-09 2023-07-21 西安交通大学医学院第二附属医院 Catheter connecting device suitable for high-degree tortuous intravascular interventional therapy

Similar Documents

Publication Publication Date Title
JP3955897B2 (en) Ultrasonic therapy device
JP5535225B2 (en) System and method for ultrasonic treatment of thyroid and parathyroid glands
US7722539B2 (en) Treatment of unwanted tissue by the selective destruction of vasculature providing nutrients to the tissue
US7686763B2 (en) Use of contrast agents to increase the effectiveness of high intensity focused ultrasound therapy
US9630030B2 (en) Image guided plaque ablation
WO2006063357A1 (en) Treatment of vascular occlusions by interacorporeal and extracorporeal application of ultrasound
JPWO2020002177A5 (en)
US11033753B2 (en) Treatment method
JP2005518861A (en) Improved system and method for deploying an implantable medical device
JP2004357792A (en) Vascular restenosis preventive therapeutic apparatus by sound pressure wave induced by irradiation of high strength pulse light
US20120004546A1 (en) System and Method for Treating Hemorrhoids
JPWO2020002179A5 (en)
US20210379395A1 (en) Treatment Method and Treatment System
JP2012517252A (en) System and method for pretreatment planning for photodynamic phototherapy
US6488628B1 (en) Method for ultrasonically profiling the distribution of an administered medicament
CN204121122U (en) A kind of Internal Medicine-Oncology interventional therapy needle guidance apparatus
WO2019240032A1 (en) Diagnosis method, diagnosis system, and control method for diagnosis system
JP2020108764A (en) Balloon catheter with distal end having recessed shape
US20210379396A1 (en) Treatment method and treatment system
US20210379398A1 (en) Treatment method and treatment system
KR102481165B1 (en) Light therapy apparatus of sphincter using balloon catheter and the method thereof
US20170113066A1 (en) System to produce anatomical reproducibility and detect motion during a medical treatment and methods of use
KR101971997B1 (en) Device and method for providing ultrasound
US11185250B2 (en) Medical devices and related methods of use
US20050209669A1 (en) System for stent placement in a vasculature bifurcation