JPWO2008007674A1 - Chemical filling device - Google Patents

Abstract

The chemical filling device 100 includes a cylinder holder 110 and a piston holder 120. The cylinder holder 110 includes a flange support arm 111 and an adapter 150 that is detachably attached to the flange support arm 111. The flange support arm 111 supports the cylinder flange of the chemical syringe having the largest cylinder diameter among the chemical syringes filled with the chemical solution in the chemical solution filling apparatus 100. The adapter 150 includes a flange support portion 152 that supports a cylinder flange of a chemical syringe whose diameter is smaller than that of the chemical syringe.

Description

  The present invention relates to a chemical liquid filling device for filling a chemical liquid syringe with a chemical liquid.

Chemical syringes are widely used in the medical field. For example, CT (Computed Tomography) scanner, MRI (Magnetic)
In diagnostic imaging devices such as a Resonance Imaging (PET) device, a PET (Positron Emission Tomography) device, an angio device, and an MRA (MR Angio) device, a chemical syringe is used to inject a medical solution such as a contrast medium or physiological saline into a subject. It is done.

  A chemical solution used for inspection by an image diagnostic apparatus often has a high viscosity. For this reason, it is burdensome for the operator to manually fill the chemical syringe with the chemical solution. Therefore, Patent Document 1 and Patent Document 2 disclose a chemical liquid filling apparatus that automatically fills a chemical liquid into a chemical syringe.

  The chemical liquid filling device disclosed in Patent Document 1 includes a cylinder holder that holds a cylinder of the chemical liquid syringe, and a drive mechanism that moves the piston holder relative to the cylinder holder. When the operator inputs the inspection conditions from the input unit while holding the cylinder and piston of the chemical syringe on the cylinder holder and the piston holder, the chemical filling device determines the amount of the necessary chemical based on the input inspection conditions. The piston is moved according to the calculated amount of the chemical solution.

  Patent Document 2 describes that a chemical liquid filling device acquires data related to a chemical liquid and data related to a syringe, and fills the chemical liquid syringe with the chemical liquid based on these data. The chemical liquid filling device has a concave portion that holds a cylinder of the chemical liquid syringe and a rod that holds the piston of the chemical liquid syringe, and can slide the rod to fill the chemical liquid syringe with the chemical liquid.

Patent Document 1: JP 2000-189515 A Patent Document 2: JP 2004-313579 A

  As described above, the conventional chemical liquid filling device holds the chemical liquid syringe by separately holding the cylinder and the piston of the chemical liquid syringe and relatively moving the cylinder and the piston. However, there are a plurality of types of chemical liquid syringes having different capacities, for example, for 100 ml and 200 ml, and in many cases, the outer diameters of the cylinder and its flange are different depending on the capacity. Since the conventional chemical liquid filling device corresponds to only one type of outer diameter for holding the cylinder, when filling a plurality of types of chemical liquid syringes with a chemical liquid, the chemical liquid filling device for each type of the chemical liquid syringe It was necessary to prepare.

  In order to make it possible to fill a plurality of types of chemical liquid syringes, Patent Document 2 discloses that an adapter used in a chemical liquid injection apparatus can be attached to the chemical liquid filling apparatus, and a chemical liquid syringe with a small outer diameter is attached to the adapter. It is described that it can be attached to the chemical solution filling device via the. The adapter used in the chemical solution injector is a substantially semi-cylindrical member that holds the outer peripheral portion of the cylinder and the flange on the inner surface. Therefore, the size of the adapter itself is relatively large. Therefore, since it is necessary for the chemical filling apparatus to be attached with such an adapter, the size is limited when the apparatus is miniaturized.

  Furthermore, the conventional chemical solution filling apparatus fills the chemical solution into the chemical solution syringe by a predetermined amount or an amount obtained from the input data. Therefore, there is also a demand for manually setting the filling amount of the chemical solution arbitrarily.

  A first object of the present invention is to provide a chemical solution filling apparatus that can be downsized while being configured to be able to fill a plurality of types of chemical solution syringes having different diameters.

  Furthermore, in addition to the first object, the present invention has a second object to provide a chemical liquid filling device that can arbitrarily set the filling amount of the chemical liquid.

  A chemical liquid filling apparatus according to the present invention is a chemical liquid filling apparatus that fills a chemical liquid syringe with a cylinder and a piston that is movably provided in the cylinder, the cylinder holder supporting the cylinder, and the cylinder in the cylinder holder. A piston pulling mechanism for pulling out the piston of the supported liquid syringe from the cylinder. Here, the cylinder holder has a plurality of cylinder flange support portions that are adapted to a plurality of types of cylinders having different diameters and support cylinder flanges provided in the cylinders.

  In the chemical solution filling apparatus of the present invention, since the cylinder holder has a plurality of cylinder flange support portions, a plurality of types of chemical solution syringes having different cylinder diameters can be mounted in a replaceable manner. In addition, since the cylinder holder supports the cylinder flange, not the outer peripheral surface of the cylinder, the size can be minimized.

  In the chemical solution filling apparatus of the present invention, the cylinder holder includes, for example, the following modes.

  In the first aspect, a pair of flange support arm portions that are one of a plurality of cylinder flange support portions that support the cylinder flange of the cylinder having the largest diameter among the plurality of types of cylinders, and are detachably attached to the flange support arm portions. And at least one adapter provided with a cylinder flange support portion adapted to a cylinder other than the cylinder having the largest diameter among the plurality of types of cylinders.

  In the second aspect, a pair of flange support arm portions that are one of a plurality of cylinder flange support portions that support the cylinder flange of the cylinder having the largest diameter among the plurality of types of cylinders, and are detachable from the flange support arm portions. And an adapter having a plurality of cylinder flange support portions respectively adapted to a plurality of types of cylinders other than the cylinder having the largest diameter among the plurality of types of cylinders.

  In the third aspect, the cylinder holder is formed with a plurality of cylinder flange support portions in a step shape.

  Further, in the chemical liquid filling device of the present invention, the piston pull-out mechanism has a piston holder that holds the piston flange of the piston and pulls the piston out of the cylinder by moving with respect to the cylinder holder, and the moving direction of the piston holder It is preferable to further include a filling amount setting section that includes an operation section that can be adjusted in position in a direction parallel to the position, and that stops the movement of the piston holder at a position corresponding to the position of the operation section. According to this, the position of the operation unit is adjusted according to the amount of the chemical liquid to be filled, and the chemical liquid filling amount to the chemical liquid syringe is set.

  In this case, the filling amount setting unit may further include a holder detection sensor that detects the piston holder, and may be configured to stop the movement of the piston holder when the piston holder is detected by the holder detection sensor.

  According to the chemical solution filling apparatus of the present invention, the cylinder holder is configured as described above, so that a plurality of types of chemical solution syringes having different cylinder diameters can be filled, but the cylinder is held. Thus, the entire chemical solution filling apparatus can be reduced in size. Moreover, the filling amount of a chemical | medical solution can be arbitrarily set by providing a filling amount setting part.

It is a perspective view of the chemical | medical solution filling apparatus by the 1st Embodiment of this invention. It is a perspective view of the state which equipped the chemical | medical solution filling apparatus shown in FIG. 1 with the 1st chemical | medical solution syringe. It is a perspective view of the state which mounted | wore the 2nd chemical | medical solution syringe with the chemical | medical solution filling apparatus shown in FIG. It is a perspective view shown in the state which took out the piston holder shown in FIG. 1 from the housing | casing of a chemical | medical solution filling apparatus. It is a figure which shows typically the various sensors and filling amount setting part which are provided inside the housing | casing of the chemical | medical solution filling apparatus shown in FIG. It is a top view of the filling amount setting part shown in FIG. It is a side view of the filling amount setting part shown in FIG. It is a top view of the fixing | fixed part to a guide shaft which shows the other example of the filling amount setting part. It is a side view in the part corresponding to FIG. 7A of the filling amount setting part shown to FIG. 7A. It is a top view of the fixing | fixed part to a guide shaft which shows the other example of the filling amount setting part. It is a side view in the part corresponding to Drawing 8A of the filling amount setting part shown in Drawing 8A. It is a top view of a cylinder holder used in a 2nd embodiment of the present invention. FIG. 9B is a front view of the cylinder holder shown in FIG. 9A. In FIG. 9B, it is a figure which shows the state which supported the cylinder of the 1st chemical | medical solution syringe. It is a figure which shows the state which supported the cylinder of the 2nd chemical | medical solution syringe in FIG. 9B. It is a perspective view of the cylinder holder which combined the 1st Embodiment and 2nd Embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 100 Chemical solution filling apparatus 101 Case 110,160 Cylinder holder 111 Flange support arm 120 Piston holder 131 Guide shaft 132 Ball screw shaft 140 Filling amount setting part 141 1st operation lever 142 2nd operation lever 145 Holder detection sensor 146 Stopper 150,170 Adapter 151, 162 Recess 152, 163, 164, 171, 172 Flange support 153 Fitting groove 200, 210 Chemical syringe 201, 211 Cylinder 201a, 211a Cylinder flange 202, 212 Piston

(First embodiment)
FIG. 1 is a perspective view of a chemical liquid filling apparatus according to a first embodiment of the present invention. 2 is a perspective view of a state in which the first chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG. 1, and FIG. 3 is a perspective view of a state in which the second chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG. FIG.

  In the chemical liquid filling device 100 of the present embodiment, either the first chemical liquid syringe 200 shown in FIG. 2 or the second chemical liquid syringe 210 shown in FIG. By operating the chemical liquid syringes 200 and 210, the first or second chemical liquid syringes 200 and 210 are filled with the chemical liquid.

First, the chemical syringes 200 and 210 will be described with reference to FIGS.
The chemical syringes 200 and 210 include cylinders 201 and 211 and pistons 202 and 212 inserted into the cylinders 201 and 211 so as to be reciprocally movable in the axial direction thereof. The cylinders 200 and 210 have conduit portions 201b and 211b at one end thereof. The pistons 202 and 212 are inserted into the cylinders 201 and 211 from the other end which is the end opposite to the one ends of the cylinders 201 and 211. Cylinder flanges 201a and 211a are formed at the other ends of the cylinders 201 and 211, respectively. Similarly, piston flanges 202a and 212a are formed at the ends of the pistons 202 and 212 opposite to the side inserted into the cylinders 201 and 211, respectively.

  The capacity of first chemical liquid syringe 200 is larger than the capacity of second chemical liquid syringe 210. For example, the capacity of the first chemical liquid syringe 200 is 200 ml, and the capacity of the second chemical liquid syringe 210 is 100 ml. Therefore, when comparing the first chemical syringe 200 and the second chemical syringe 210, the first chemical syringe 200 is larger in size than the second chemical syringe 210. Specifically, the diameter of the cylinder 201 and the cylinder flange 201a of the first chemical liquid syringe 200 is larger than the diameter of the cylinder 211 and the cylinder flange 211a of the second chemical liquid syringe 210. In the present embodiment, the strokes of the pistons 202 and 212 are the same for both the first chemical liquid syringe 200 and the second chemical liquid syringe 210. However, the strokes of the pistons 202 and 212 may be different between the first chemical syringe 200 and the second chemical syringe 210.

  Next, the chemical solution filling apparatus 100 will be described.

  The chemical liquid filling device 100 includes a cylinder holder 110 and a piston holder 120 that is disposed so as to face the cylinder holder 110 and is supported to move in a direction toward and away from the cylinder holder 110. Although the direction in which the cylinder holder 110 and the piston holder 120 face each other is not particularly limited, in the present embodiment, both are arranged so that the piston holder 120 is positioned below the cylinder holder 110 in the usage state of the chemical liquid filling device 100. ing.

  The cylinder holder 110 includes two flange support arms 111 fixed to the housing 101 and an adapter 150 that is detachably attached to the flange support arm 111.

  The flange support arm 111 supports the cylinder flange 201a of the first chemical syringe 200, and is arranged in parallel at intervals in a direction orthogonal to the moving direction of the piston holder 120. The upper surface (surface opposite to the surface facing the piston holder 120) of these flange support arms 111 is a mounting surface 111a on which the cylinder flange 201a is mounted.

  As shown in FIG. 2, the cylinder flange 201 a is placed on the placement surface 111 a with the conduit portion 201 b facing upward, whereby the cylinder 201 of the first chemical syringe 200 is supported on the cylinder holder 110. The In this state, the piston 202 of the first chemical solution syringe 200 extends from between the two flange support portions 111 toward the piston holder 120, and the piston 202 between the two flange support portions 111 is filled with the chemical solution. Is accompanied by movement. Therefore, the interval between the two flange support arms 111 is set to an interval that does not interfere with the flange support arm 111 even if the piston 202 moves.

  The adapter 150 is for allowing the second chemical liquid syringe 210 to be attached instead of the first chemical liquid syringe 200, and the two fitting grooves 153 into which the flange support arms 111 of the cylinder holder 110 are respectively inserted. On both sides. By inserting the flange support arm 111 into these fitting grooves 153, the adapter 150 is detachably attached to the cylinder holder 110. A recess 151 for receiving the piston 212 of the second chemical liquid syringe 210 from the side is formed in a portion between the fitting grooves 153 of the adapter 150, and the adapter 150 is formed in a substantially U shape as a whole.

  The recess 151 is formed so that the opening size gradually increases on the side farther from the piston holder 120 than on the side closer to the piston holder 120. As a result, a flange support portion 152 protruding toward the center of the recess is formed in a step shape on the inner peripheral surface of the adapter 140 forming the recess 151. As shown in FIG. 3, the flange support portion 152 supports the cylinder 211 by placing the cylinder flange 211a of the second chemical liquid syringe 210 with the conduit portion 211b facing upward.

  As shown in FIG. 4, the piston holder 120 has a holder main body 121 and a slider portion 122 provided integrally with the holder main body 121, and together with a piston holder driving means for driving the piston holder 120, a piston pulling mechanism Configure.

  The slider portion 122 constitutes a part of a ball screw mechanism that is a piston holder driving means. The ball screw mechanism includes a ball screw shaft 132 disposed in parallel to a direction in which the flange support arm 111 (see FIG. 1) and the piston holder 120 face each other, and a ball screw nut that is screwed onto the ball screw shaft 132. The slider part 122 functions as this ball screw nut. Further, in order to prevent the slider portion 122 from rotating, a guide shaft 131 disposed in parallel with the ball screw shaft 132 passes through the slider portion 122.

  The slider portion 122, the guide shaft 131, and the ball screw shaft 132 are accommodated in the housing 101 (see FIG. 1) of the chemical liquid filling device 100.

  As shown in FIG. 1, the holder main body 121 extends outside the housing 101 and is positioned below the flange support arm 111. The holder main body 121 has two flange presser arms 121 a arranged in the same manner as the flange support arm 111. The interval between the two flange pressing arms 121a is larger than the diameter of the piston 202 and smaller than the diameter of the piston flange 202a. As shown in FIG. 2, the holder main body 121 has the cylinder holder 110 and the piston in a state where the cylinder 201 is supported on the flange support arm 111 and in a state where the cylinder 211 is supported on the adapter 150 as shown in FIG. 3. It is located between the flange 202a.

  According to the above configuration, the piston holder 120 moves in the axial direction of the ball screw shaft 132 by rotating the ball screw shaft 132. Depending on the rotation direction of the ball screw shaft 132, the piston holder 120 moves in a direction away from the cylinder holder 110 or moves in a direction approaching the cylinder holder 110. As a driving source for the ball screw shaft 132, for example, a stepping motor (not shown) can be used.

  As described above, in the chemical liquid filling device 100 of this embodiment, the first chemical liquid syringe 200 is mounted by supporting the cylinder flange 201a on the flange support arm 111 and holding the piston flange 202a by the piston holder 120. (See FIG. 2). Further, the cylinder flange 211a is supported on the adapter 150, and the piston flange 212a is held by the piston holder 120, whereby the second chemical syringe 210 is mounted (see FIG. 3).

  The adapter 211 as described above corresponds to the cylinder 211 of the second chemical syringe 210, but such an adapter is not necessary for the piston 212. When injecting a drug solution into a subject using a drug solution injection device (not shown), the drug solution injection device pushes the piston into the cylinder with the piston flange chucked. Since the rod portion and flange of the piston can be designed regardless of the capacity of the chemical syringe, in general, the dimensions of the piston flange are often common regardless of the capacity of the chemical syringe. Therefore, also in the chemical liquid filling apparatus 100 of this embodiment, the piston holder 120 can be used in common for the chemical liquid syringes 200 and 210.

  The chemical liquid filling device 100 of this embodiment includes an initialization sensor for setting the initial position of the piston holder 120, a syringe detection sensor for detecting the mounting of the chemical liquid syringes 200 and 210, and a filling amount for setting the filling amount of the chemical liquid. It further has a setting unit. These sensors and the filling amount setting unit are built in the housing 101.

  Referring to FIG. 5, the arrangement of the initialization sensor 131, the syringe detection sensor 136, and the filling amount setting unit 140 in the housing 101 is schematically shown.

  The initialization sensor 131 has a limit switch 132. This limit switch 132 has a lever type actuator. When the piston holder 120 is in the initial position, the slider portion 122 abuts to displace the actuator (indicated by a broken line in the figure). It is arranged at the position to turn on. When the limit switch 132 is turned on, it is detected that the piston holder 120 is in the initial position.

  The syringe detection sensor 136 is located above the cylinder holder 110 and includes a limit switch 137 and a rod 138 that is slidably supported. The rod 138 has a tip projecting from the side surface of the housing 101 at a position facing the outer peripheral surface of the cylinder when the chemical syringe is supported on the cylinder holder 110, and the tip is supported by a spring (not shown). It is biased in a direction protruding from the side surface of the body 101. The limit switch 137 has a lever-type actuator that is displaced when the rod 138 is pushed into the housing 101.

  The syringe detection sensor 136 is off when the chemical liquid syringe is not attached to the chemical liquid filling device 100. When the chemical syringe is attached, the rod 138 is pushed into the housing 101 by the cylinder of the attached chemical syringe. The pushed rod 138 displaces the actuator of the limit switch 137, whereby the syringe detection sensor 136 is turned on. When the syringe detection sensor 136 is turned on, it is detected that the chemical liquid syringe is attached to the chemical liquid filling device 100.

  Here, it is preferable that the target drug solution syringes to be detected by the syringe detection sensor 136 are both the first and second drug solution syringes 200 and 210, but even if only the first drug solution syringe 200 having a large diameter is used. Good. In addition, as the output at the time of detection, a sensor that takes a plurality of states according to the displacement of the actuator is used instead of simple on / off, and which of the first chemical liquid syringe 200 and the second chemical liquid syringe 210 is mounted. May be determined by the output from the sensor.

  The initialization sensor 131 and the syringe detection sensor 136 described above are merely examples, and any optical type can be used as long as the chemical liquid syringe can be attached to the chemical liquid filling device 100 and the initialization position of the piston holder 120 can be detected. Any detection device such as a sensor can be used.

  The filling amount setting unit 140 is disposed below the piston holder 120, that is, at a position farther from the cylinder holder 110 than the piston holder 120. The filling amount setting unit 140 will be described with reference to FIGS. 6A and 6B.

  The filling amount setting unit 140 includes a first operation lever 141 through which the above-described guide shaft 131 and the ball screw shaft 132 pass and is slidably supported with respect to the guide shaft 131 and the ball screw shaft 132. A second operation lever 142 is provided on the first operation lever 141 so as to be rotatable around the support shaft 143 by a support shaft 143 arranged in parallel with the guide shaft 131. The support shaft 143 supports the second operation lever 142 at the intermediate portion in the longitudinal direction of the second operation lever 142.

  One end portions of the first operation lever 141 and the second operation lever 142 are operation knob portions 141a and 142a, respectively. The operation knob portions 141a and 142a are arranged to face each other and extend to the outside of the housing 101 (see FIG. 1). The second operation lever 142 is urged by the torsion coil spring 144 held by the support shaft 143 in a direction in which the operation knob portion 142 a is separated from the operation knob portion 141 a of the first operation lever 141.

  The tip of the second operation lever 142 (the end opposite to the side having the operation knob 142a) extends to a position facing the guide shaft 131, and a stopper 146 is fixed to the surface facing the guide shaft 131. Has been. The stopper 146 is preferably made of a material having a high coefficient of static friction with respect to the guide shaft 131, such as rubber.

  When the operation knobs 141a and 142a are not operated, the second operation lever 142 is urged by the urging force of the torsion coil spring 144 as shown by a solid line in FIG. The surface is pressurized. As a result, the filling amount setting unit 140 is held at that position without sliding with respect to the guide shaft 131.

  On the other hand, when the second operation lever 142 is rotated against the urging force of the torsion coil spring 144 by the operation of the operation knobs 141a and 142a as shown by a one-dot chain line in FIG. 6A, the stopper 146 is moved from the guide shaft 1341. Leave. As a result, the filling amount setting unit 140 can be arbitrarily moved along the axial direction of the guide shaft 131. That is, the first operation lever 141 is provided so that its position can be adjusted in a direction parallel to the moving direction of the piston holder 120.

  A holder detection sensor 145 that detects the piston holder 120 (see FIG. 1) is provided at the tip of the first operation lever 141. As the holder detection sensor 145, any means such as an optical sensor or a limit switch can be used as long as it can detect the piston holder 120. Here, an optical sensor having a light emitting element and a light receiving element is used as the holder detection sensor 145.

  In order to enable detection of the piston holder 120 by the holder detection sensor 145, a shielding plate 122a is provided so as to protrude from the slider portion 122 of the piston holder 120, as shown by a one-dot chain line in FIG. 6B. More specifically, the shielding plate 122a extends between the light emitting element and the light receiving element of the holder detection sensor 145 on the side of the slider part 122 facing the filling amount setting part 140.

  According to the above configuration, the piston holder 120 can be detected by the proximity of the piston holder 120 and the filling amount setting unit 140 so that the shielding plate 122a enters between the light emitting element and the light receiving element. it can.

  Next, the chemical | medical solution filling operation | movement by the chemical solution filling apparatus 100 of this form is demonstrated.

  When the chemical solution filling apparatus 100 is powered on, the piston holder 120 is moved to an initial position that is close to the cylinder holder 110. In this state, the first chemical solution syringe 200 or the second chemical solution syringe 210 is attached to the chemical solution filling apparatus 100. When the chemical liquid syringes 200 and 210 are attached, this is detected by the syringe detection sensor 136, and the chemical liquid filling apparatus 100 enters a standby state.

  The subsequent operation of the chemical solution filling apparatus 100 will be described by taking as an example the case of filling the first chemical solution syringe 200 with the chemical solution. When the chemical solution syringe 200 is attached to the chemical solution filling apparatus 100, the adapter 150 is not used and the cylinder flange 201 a is placed on the flange support arm 111. Since the piston holder 120 is in the initial position, the piston holder 120 is located between the flange support arm 111 and the piston flange 202a. In addition, the chemical | medical solution container (not shown) is connected to the conduit | pipe part 201b of the chemical | medical solution syringe 200 via the tube (not shown).

  If the 1st chemical | medical solution syringe 200 is mounted | worn, the filling amount of the chemical | medical solution to this chemical | medical solution syringe 200 will be set. The filling amount is set by the filling amount setting unit 140. First, the operator operates the operation knobs 141a and 142a to set the filling amount setting unit 140 at a predetermined position that is determined according to the filling amount of the drug solution into the drug solution syringe 200. In order to make it easy to set the position of the filling amount setting unit 140, a scale (not shown) indicating the filling amount associated with the position of the filling amount setting unit 140 is attached to the housing 101 in advance. Good.

  When the filling amount of the chemical solution into the chemical solution syringe 200 is set, the operator turns on a start switch (not shown) provided in the chemical solution filling apparatus 100. Then, the piston holder driving mechanism described above operates, and the piston holder 120 moves away from the cylinder holder 110. As the piston holder 120 moves, the piston 202 is pulled out from the cylinder 201 and the inside of the cylinder 201 becomes negative pressure, so that the chemical solution is filled into the cylinder 201 from the chemical solution container.

  The moving speed of the piston holder 120 at the time of filling the chemical liquid can be appropriately set according to the viscosity of the chemical liquid to be filled. For example, when the chemical solution is a contrast agent, it is preferable to move the piston holder 120 so that the filling rate of the chemical solution is in the range of 1.0 ml / sec to 3.0 ml / sec. Also. The moving speed of the piston holder 120 may be variable so that the injection speed of the chemical liquid can be adjusted according to the type of the chemical liquid.

  The movement of the piston holder 120 during the filling of the chemical liquid is also a movement in a direction approaching the filling amount setting unit 140. When the piston holder 120 moves toward the filling amount setting unit 140 and the shielding plate 122a is detected by the holder detection sensor 145 as shown in FIG. 6B, the operation of the piston holder driving mechanism is stopped.

  When the operation of the piston holder driving mechanism is stopped, the operation of filling the chemical liquid into the first chemical liquid syringe 200 is completed. When the chemical liquid filling operation is completed, the chemical syringe 200 is removed from the chemical liquid filling device 100.

  The chemical solution is filled into the chemical syringe 200 while the piston 202 is pulled out from the cylinder 201. Therefore, when the operation of the piston holder driving mechanism is stopped, a force in the direction of being pushed into the cylinder 201 acts on the piston 201 from the relationship between the internal pressure of the cylinder 201 and the atmospheric pressure. Due to this force, the cylinder flange 201a and the piston flange 202a are pressed against the flange support arm 111 and the piston holder 120, respectively, and it may be difficult to remove the chemical syringe 200.

  Therefore, it is preferable to move the piston holder 120 away from the flange support arm 111 by activating the piston pulling mechanism reversely after the operation of the piston holder driving mechanism for filling the chemical liquid is stopped. Thereby, the chemical solution syringe 200 can be easily detached from the chemical solution filling apparatus 100.

  The above is the filling operation of the chemical solution into the first chemical solution syringe 200. When filling the second chemical solution syringe 210 with the chemical solution, the adapter 150 is attached to the flange support arm 111, and the cylinder flange 211 a is mounted on the flange mounting surface 152 of the adapter 150, thereby the second chemical solution syringe 210. Is attached to the chemical solution filling apparatus 100. Subsequent procedures and operations are the same as those of the first chemical syringe 200.

  As described above, the cylinder holder 110 is configured such that the adapter 150 suitable for the second chemical liquid syringe 210 is detachably provided on the pair of flange support arms 111 suitable for the first chemical liquid syringe 200. The chemical solution can be filled into the two types of chemical solution syringes 200 and 210 having different diameters.

  In addition, the flange support arm 111 supports the cylinder flange 201a, and the adapter 150 is also attached to the flange support arm 111 and has a stepped recess 151 that supports the cylinder flange 212a of the second chemical syringe 210. It is formed as a part.

  Since both the flange support arm 111 and the adapter 150 support only the cylinder flanges 201a and 211a, not the outer peripheral surfaces of the chemical syringes 200 and 210, they can be configured to be extremely simple and small. As a result, the chemical liquid filling apparatus 100 according to the present embodiment can be significantly reduced in size compared to the conventional chemical liquid filling apparatus, whether viewed from the overall configuration including the adapter 150 or from the adapter 150 alone. .

  Furthermore, the chemical liquid filling device 100 of this embodiment has a filling amount setting unit 140 for stopping the movement of the piston holder 120, and the filling amount setting unit 140 is provided so that the position of the filling amount setting unit 140 can be adjusted. Can be set arbitrarily. Further, by supporting the first operation lever 141 and the piston holder 120 of the filling amount setting unit 140 on a common support member (in this embodiment, the guide shaft 131 and the ball screw shaft 132), a new for the filling amount setting unit 140 is obtained. No support member is required. This simplifies the structure, so that an increase in the size of the chemical solution filling apparatus 100 due to the provision of the filling amount setting unit 140 can be minimized.

  In the embodiment described above, the filling amount setting unit 140 has shown an example in which the filling amount setting unit 140 is fixed at an arbitrary position using the static frictional force between the guide shaft 131 and the stopper 146. The structure for fixing 140 is not limited to this.

  Some examples are described below. In the following description, differences from the above-described embodiment will be mainly described, and common configurations will not be particularly referred to. In the drawings to be referred to in the following description, the same reference numerals as those used in the above-described embodiment are attached to the configurations common to the above-described embodiment.

  In the example shown in FIGS. 6A and 6B, the meshing hook 147 extends from the distal end portion of the second operation lever 142 toward the guide shaft 131. On the other hand, a rack 131 b is provided in a region of the guide shaft 131 facing the meshing hook 147. The rack 131a has a large number of teeth arranged in the axial direction of the guide shaft 131.

  According to the above configuration, in a normal state where the first operation lever 141 and the second operation lever 142 are not operated, the engagement hook 147 is engaged with the rack 131a, thereby fixing the position of the filling amount setting unit. When the second operation lever 142 is operated with respect to the first operation lever 141 to release the engagement of the engagement hook 147 with the rack 131a, the filling amount setting unit can be moved along the guide shaft 131.

  In the example shown in FIGS. 7A and 8B, the positioning pin 148 extends from the distal end portion of the second operation lever 142 toward the guide shaft 131. On the other hand, a plurality of positioning holes 131 b are provided in the region facing the positioning pins 148 of the guide shaft 131 at regular intervals along the axial direction of the guide shaft 131.

  According to the above configuration, in a normal state where the first operation lever 141 and the second operation lever 142 are not operated, the positioning pin 148 engages with the positioning hole 131b, thereby fixing the position of the filling amount setting unit. Is done. When the second operation lever 142 is operated with respect to the first operation lever 141 and the engagement of the positioning pin 148 to the positioning hole 131b is released, the filling amount setting unit can be moved along the guide shaft 131. In this configuration, the position of the filling amount setting portion with respect to the guide shaft 131 can be adjusted by changing the positioning hole 131b with which the positioning pin 148 is engaged.

  As described above, in the present embodiment, the chemical liquid filling apparatus including the filling amount setting unit has been described as being able to arbitrarily set the filling amount of the chemical liquid. However, in the present invention, when the chemical liquid is filled, the movement amount of the piston holder 120 is determined in advance, and the chemical liquid can be filled by a predetermined amount. In that case, the filling amount setting unit is unnecessary.

  Further, in this embodiment, an example in which the adapter 150 is detachably provided so that two kinds of chemical syringes 200 and 210 having different diameters can be filled with the chemical solution is shown. It is also possible to use at least one other adapter having a different protrusion amount of the flange support portion. Thus, by using the further adapter, it can respond also to three or more types of liquid syringes having different diameters.

(Second Embodiment)
In 1st Embodiment, the chemical | medical solution filling apparatus which can be filled with a chemical | medical solution to two types of chemical | medical solution syringes from which a diameter differs was demonstrated using the adapter for cylinder holders. This embodiment demonstrates the example of the chemical | medical solution filling apparatus which can be filled with a chemical | medical solution to two types of chemical | medical solution syringes from which a diameter differs by using a cylinder holder as a specific shape without using an adapter.

  FIG. 9A shows a plan view of a cylinder holder 160 used in the second embodiment of the present invention. FIG. 9B is a front view of the cylinder holder 160. Since the configuration other than the cylinder holder 160 in the chemical liquid filling device of the present embodiment may be the same as that of the first embodiment, the description thereof will be omitted, and not only FIG. 9A and FIG. 9B but also the first embodiment. The cylinder holder 160 of this embodiment will be described with reference to the drawings used in the description.

  The cylinder holder 160 is configured by a generally plate-like member, and can be integrally provided in the housing of the chemical liquid filling device, as in the first embodiment. The cylinder holder 160 has a recess 162 that is partially opened in the thickness direction of the cylinder holder 160 so that the pistons 201 and 211 (see FIGS. 2 and 3) of the chemical syringes 200 and 210 can be received from the side. It is formed through. First and second flange support portions 163 and 164 are formed in a step shape on the inner peripheral surface of the recess 162.

  As shown in FIG. 10, the second flange support portion 164 supports the cylinder flange 211 a of the second chemical syringe 210 and is formed around the recess 162 as a first step. The first flange support portion 163 supports the cylinder flange 201a of the first chemical syringe 200, and is formed around the second flange support portion 164 as a second step.

  As described above, the cylinder holder 160 is configured to have the two flange support portions 163 and 164 provided in a staircase shape, so that two types of drug solution syringes having different diameters are filled with a drug solution without using an adapter. be able to. Further, by not using an adapter, the number of parts can be reduced and the adapter can be lost.

  In the second embodiment, the cylinder holder can be configured by having three or more flange support portions provided in a step shape. According to this, it can respond also to three or more types of chemical | medical solution syringes from which a diameter differs.

  Furthermore, in this invention, it can also respond | correspond to three or more types of chemical | medical solution syringes combining 1st Embodiment and 2nd Embodiment.

  For example, as shown in FIG. 12, an adapter 170 attached to the same flange support arm 111 as shown in FIG. 1 has a structure having two flange support portions 171 and 172 provided in a step shape. Thereby, it is possible to cope with three types of chemical syringes, one type of chemical syringe supported by the flange support arm 111 and two types of chemical syringes supported by the adapter 170. The flange support arm 111 supports the chemical syringe having the largest cylinder diameter among the three types of chemical syringes. Of course, if the number of stages of the flange support portion of the adapter 170 is three or more, it is possible to cope with four or more types of liquid syringes.

Claims (8)

A chemical liquid filling device for filling a chemical liquid syringe with a chemical liquid syringe having a cylinder and a piston provided movably in the cylinder,
A cylinder holder for supporting the cylinder;
A piston pull-out mechanism for pulling out the piston of the chemical syringe whose cylinder is supported by the cylinder holder from the cylinder;
With
The said cylinder holder is a chemical | medical solution filling apparatus which has the some cylinder flange support part which supports the cylinder flange each provided in the said cylinder adapted to the multiple types of cylinder from which a diameter differs. The cylinder holder is
A pair of flange support arm portions that are one of the plurality of cylinder flange support portions, supporting a cylinder flange of a cylinder having the largest diameter among the plurality of types of cylinders;
At least one adapter provided with the cylinder flange support portion that is detachably provided on the flange support arm portion and is adapted to a cylinder other than the cylinder having the largest diameter among the plurality of types of cylinders;
The chemical | medical solution filling apparatus of Claim 1 which has these. The cylinder holder is
A pair of flange support arm portions that are one of the plurality of cylinder flange support portions, supporting a cylinder flange of a cylinder having the largest diameter among the plurality of types of cylinders;
An adapter provided with a plurality of cylinder flange support portions, which is detachably provided on the flange support arm portion, and is respectively adapted to a plurality of types of cylinders other than the cylinder having the largest diameter among the plurality of types of cylinders;
The chemical | medical solution filling apparatus of Claim 1 which has these.   The chemical solution filling device according to claim 2 or 3, wherein a fitting groove into which the flange support arm portion is inserted is formed in the adapter.   The chemical solution filling device according to claim 1, wherein the plurality of cylinder flange support portions are formed in a step shape on the cylinder holder. The piston pull-out mechanism has a piston holder that holds a piston flange of the piston and pulls the piston out of the cylinder by moving with respect to the cylinder holder.
An operation unit provided so that the position of the piston holder can be adjusted in a direction parallel to the moving direction of the piston holder, and further includes a filling amount setting unit that stops the movement of the piston holder at a position corresponding to the position of the operation unit. The chemical solution filling apparatus according to any one of 1 to 5. The filling amount setting unit further includes a holder detection sensor for detecting the piston holder,
The chemical | medical solution filling apparatus of Claim 6 which stops the movement of the said piston holder when the said piston holder is detected by the said holder detection sensor.   The chemical solution filling device according to claim 6 or 7, wherein the piston holder and the operation unit are supported by a common support member so as to be movable.

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