JPWO2007037335A1 - Suture device - Google Patents

Abstract

The present invention is a suture instrument that is inserted into a body, to which a suture thread that sutures a perforation is connected, and to release an elongated anchor placed in the tissue, which is introduced into the tissue from the proximal end on the proximal side. Extending to the end, having a flexible base, and being disposed at the distal end of the base, wherein a plurality of the anchors can be accommodated therein, and a tip for discharging the anchor is substantially directed toward the proximal end of the base An anchor holder that is provided, and a tip position changing mechanism that is provided to change the tip position of the anchor holder, and that moves the anchor holder in a direction that intersects the longitudinal axis of the base. A suturing device comprising: a position operating device that operates the distal end position changing mechanism on the hand side to operate the distal end position of the anchor holder.

Description

The present invention relates to a suture instrument that sutures a perforation by inserting a suture tool orally or transanally. For example, the present invention relates to a suturing device for suturing a perforation formed in a wall of a luminal organ.
This application claims priority based on US patent application Ser. No. 11 / 238,016, filed Sep. 28, 2005, the contents of which are incorporated herein by reference.

When a treatment is performed in the patient's body, there are a case where the patient's body is incised by surgery, and an oral endoscopic or transanal endoscopic treatment. A method for suturing an abdominal perforation surgically is shown in FIGS. 6a-6c of US Pat. No. 6,066,146. In this suturing method, the needle is punctured into the tissue near the perforation, and the anchor with the suture thread is pushed out from the needle. After the needle has been removed from the tissue, the perforation is closed by tying two sutures sandwiching the perforation.
The treatment using the endoscope is performed by passing forceps, a high-frequency treatment tool, an incision tool, a suture tool, and the like through the channel of the endoscope. For example, when performing medical treatment in the abdominal cavity using an endoscope inserted into the lumen through a natural opening in the body such as the mouth or anus, the tissue is excised or incised from the abdominal cavity. Through this hole, medical treatment is performed by approaching from the lumen into the abdominal cavity. After performing the medical practice, the formed hole is sutured with a suture tool.

Here, a method for performing suturing in a luminal organ is shown, for example, in FIGS. 6 to 9 of Japanese Patent Application Laid-Open No. 2004-601. In this suturing method, the tissue is drawn into the overtube, and the needle is passed from the near side of the tissue toward the distal end side. From the inside of the needle, an anchor with a suture is pushed out to the distal end side of the tissue. Thereafter, when the needle is pulled out, the suture penetrates into the tissue, and the tissue is tightened with the suture. Further, there is a method shown in FIGS. 1, 4, and 5A to 5C of US Pat. No. 5,297,536. In this way, the flexible endoscope is inserted in the vicinity of the perforation via the mouth or the anus. The tissue surrounding the perforation is aspirated with a flexible endoscope tube. When the O-ring attached to the outside of the tube is pushed out from the tube tip, the sucked tissue is clamped by the O-ring.
US Pat. No. 6,066,146

By the way, when passing the suture of the tissue around the perforation, it is necessary to confirm that there are no other organs around. However, it has been difficult to confirm other organs with a conventional suture instrument. Here, if the needle is penetrated with the tissue surrounding the perforation from the outside to the inside, it can be easily confirmed that the needle has penetrated the tissue. It was not easy to penetrate the needle from the outside to the inside in the state where it was in the state.
The present invention has been made in view of the above circumstances, and a main object of the present invention is to enable a suture tool for suturing a perforation to be reliably penetrated from the outside to the inside.

The present invention is a suture instrument that is inserted into a body, to which a suture thread that sutures a perforation is connected, and to release an elongated anchor placed in the tissue, which is introduced into the tissue from the proximal end on the proximal side. Extending to the end, having a flexible base, and being disposed at the distal end of the base, wherein a plurality of the anchors can be accommodated therein, and a tip for discharging the anchor is substantially directed toward the proximal end of the base An anchor holder that is provided, and a tip position changing mechanism that is provided to change the tip position of the anchor holder, and that moves the anchor holder in a direction that intersects the longitudinal axis of the base. A suturing device comprising: a position operating device that operates the distal end position changing mechanism on the hand side to operate the distal end position of the anchor holder.
In this suturing device, when the anchor holder is arranged outside through the perforation, the tip position changing mechanism is driven by the position operation device, and the anchor holder is moved in a direction intersecting with the longitudinal axis of the base. When the base is pulled back in this state, the anchor retainer passes through the tissue surrounding the perforation from the outside to the inside. When the anchor is pushed out from the tip of the anchor retainer, the anchor is released while the suture penetrates the tissue. it can.

According to the present invention, in the suturing device according to claim 1, the tip position changing mechanism changes the position by moving the anchor holder to a position offset from an axis in the length direction of the base.
In this suture instrument, when the anchor holder is offset with respect to the axis of the base, the tip of the anchor holder can be directed to the tissue surrounding the perforation.

According to the present invention, in the suturing device according to claim 1, the tip position changing mechanism changes the position by inclining the anchor holder with respect to the longitudinal axis of the base.
In this suture instrument, by tilting the anchor holder, the tip of the anchor holder can be directed to the tissue around the perforation.

According to the present invention, in the suturing device according to any one of claims 1 to 3, the anchor holder is a needle having a sharp end portion at a distal end.
In this suturing device, the tissue can be penetrated by the anchor holder, so that it is not necessary to previously form a hole in the tissue with another treatment tool or the like.

According to the present invention, in the suturing device according to any one of claims 1 to 3, a distal end of the anchor holder is a hollow needle, and the anchor is disposed in the needle.
In this suturing device, when the tissue is penetrated by the anchor holder, the anchor can be pushed out and released as it is.

The suturing device according to any one of claims 1 to 5, further comprising an adsorbing device that adsorbs the magnetic force to the anchor, and the adsorbing device is disposed so as to freely advance and retract along the base. The anchor and the attracting tool are both made of a magnetic material, one of which is a magnet.
In this suturing device, when the adsorbing tool is brought close to the anchor, the anchor is released from the anchor holding tool.

The present invention is a suture instrument that is inserted into a body, to which a suture thread that sutures a perforation is connected, and to release an elongated anchor placed in the tissue, which is introduced into the tissue from the proximal end on the proximal side. Extending to the end, having a flexible base, disposed at the distal end of the base, and capable of accommodating a plurality of the anchors therein, and a tip for releasing the anchor disposed at the distal end side of the base An anchor holder, a deflection mechanism provided to deflect the tip position of the anchor holder, and deflecting the tip of the anchor holder in a direction from the distal end toward the proximal end of the base, and the proximal side And a position operating device for operating the deflection mechanism and operating the tip position of the anchor holder.
In this suturing device, when the anchor holder is disposed outside through the perforation, the deflection mechanism is driven by the position operation device so that the anchor holder is oriented toward the proximal end side of the base. When the base is pulled back in this state, the anchor holder passes through the tissue around the perforation from the outside to the inside. When the anchor is pushed out from the tip of the anchor holder, the anchor is placed with the suture passing through the tissue. Is done.

According to the present invention, in the suturing device according to claim 7, the tip position changing mechanism changes the position by inclining the anchor holder with respect to the longitudinal axis of the base.
In this suture instrument, by tilting the anchor holder, the tip of the anchor holder can be directed to the tissue around the perforation.

According to the present invention, in the suturing device according to claim 7 or 8, the anchor holder is a needle having a sharp end at a tip.
In this suturing device, the tissue can be penetrated by the anchor holder, so that it is not necessary to previously form a hole in the tissue with another treatment tool or the like.

According to the present invention, in the suturing device according to claim 7 or 8, the tip of the anchor holder is a hollow needle, and the anchor is disposed in the needle.
In this suturing device, when the tissue is penetrated by the anchor holder, the anchor can be pushed out and released as it is.

The suturing device according to any one of claims 7 to 10, further comprising an adsorbing device that adsorbs the magnetic force to the anchor, and the adsorbing device is disposed so as to advance and retreat along the base. The anchor and the attracting tool are both made of a magnetic material, one of which is a magnet.
In this suturing device, when the adsorbing tool is brought close to the anchor, the anchor is released from the anchor holding tool.

  According to the present invention, the anchor holder can be deployed and directed toward the tissue around the perforation while the base is passed through the perforation. In this state, the anchor holder can be moved relative to the tissue. For example, the tissue can be penetrated from the outside to the inside. Therefore, the anchor can be released from the outside to the inside of the tissue with a simple operation.

It is a figure which shows schematic structure of an endoscope and a suturing device. It is sectional drawing of the front-end | tip part of a suturing device and an endoscope. It is a perspective view of a suture instrument and a tip part of an endoscope. It is a figure which shows the structure of a suture tool. It is the schematic which shows the step which inserts an endoscope in a patient's stomach and observes perforation from the inside of a stomach. It is the schematic which shows the step which observes the exterior side of the stomach. It is the schematic which shows the step which punctures a tissue with the needle | hook of a suturing device. It is the schematic which shows the step which extrudes an anchor to the exterior side of a stomach from a needle | hook. It is the schematic which indwelled two anchors on the outer side of the stomach. It is the schematic which shows the step which clamp | tightens a perforation with a suturing tool. It is the schematic explaining the operation | movement which hold | grasps a suturing tool with forceps. It is the figure which sewed perforation with a suture tool with forceps. It is the schematic which shows the rod which is an example of an exclusion apparatus. It is the schematic which shows the balloon catheter which is an example of an exclusion apparatus. It is the schematic which shows the balloon catheter which inflated the balloon. It is the schematic which shows the forceps which is an example of an exclusion apparatus. It is the schematic which shows an example of the combination of an endoscope and a suture instrument. It is the schematic which shows an example of the combination of an endoscope and a suture instrument. It is the schematic which shows an example of the combination of the endoscope and suture device using an overtube. It is the schematic which shows an example of the combination of an endoscope and an observation apparatus. It is the schematic which shows an example of the combination of an endoscope and a suture instrument. It is the schematic which shows an example of the combination of the endoscope and suture device using an overtube. It is the schematic which shows the step which observes the exterior side of the stomach. It is the schematic which shows the step which punctures a structure | tissue with the needle | hook of a suturing device from the exterior side of the stomach. It is the schematic which shows the step which extrudes an anchor to the inner side of a stomach from a needle | hook. It is the schematic which indwelled two anchors on the outer side of the stomach. It is the schematic which shows the step which clamp | tightens a perforation with a suturing tool. It is the schematic explaining the operation | movement which hold | grasps a suturing tool with forceps. It is the figure which sewed perforation with a suture tool with forceps. It is the schematic which shows the step which observes the exterior side of the stomach. It is the schematic which shows the step which punctures a tissue with the needle | hook of a suturing device. It is the schematic which shows the step which extrudes an anchor to the inner side of a stomach from a needle | hook. It is the schematic which indwelled two anchors on the outer side of the stomach. It is the schematic which shows the step which clamp | tightens a perforation with a suturing tool. It is the schematic explaining the method of inserting a needle | hook from the inner side of a stomach, after observing the inner side and outer side of a stomach with an endoscope. It is the schematic which shows an example of the combination of an endoscope and a suture instrument. It is a figure which expands and shows the structure of the front-end | tip part of a suturing device. It is A arrow directional view of FIG. 37 which shows the structure of the front-end | tip part of a suture instrument. It is a figure explaining the structure of the operation part of the suturing device passed through the endoscope. It is a figure which shows the state which opened a pair of forceps piece of a suture instrument, and is a figure explaining a procedure. It is the figure which penetrated the structure | tissue from the outer side to the inner side with the needle | hook and pushed out and ejected the 1st anchor. It is the figure which penetrated the tissue on the opposite end centering on the perforation and pushed and ejected the second anchor. It is an enlarged view of the front-end | tip part of a suturing device provided with a needle | hook so that rotation is possible. It is a figure explaining the structure of the operation part of the suturing device passed through the endoscope. It is a figure explaining the technique which shows a state by opening a needle and penetrates the needle into tissue. It is a figure explaining the operation | movement which draws an anchor by bringing a pusher close to the needle which penetrated the tissue. It is a figure explaining the operation | movement which sucks and pulls an anchor to a pusher. It is the figure which pulled apart the anchor from the pusher, and was made to detach | leave. It is an enlarged view of the front-end | tip part of the suturing device with which the needle | hook curved in the substantially U shape. It is the figure which extracted the needle | hook from the 2nd lumen and expanded. It is the figure which protruded outside from the piercing | piercing, with the needle | hook accommodated in the 2nd lumen | rumen. It is the figure which extracted the needle | hook from the 2nd lumen and expanded toward the structure | tissue. It is a figure which expands and shows the front-end | tip part of the suturing device which has a curved part which changes direction of a needle | hook. It is the figure which curved the bending part. It is a figure which expands and shows the front-end | tip part of the suturing device which has a balloon in the front-end | tip part of a sheath. It is the figure which expanded the balloon and curved the sheath. It is sectional drawing along the BB line of FIG. It is the figure which exfoliated the external organ while inflating the balloon to curve the sheath. It is a figure which expands and shows the front-end | tip part of the suturing device which the front-end | tip part of a sheath curves about 90 degrees and has a raising hook. It is a figure explaining the structure of the operation part of the suturing device passed through the endoscope. It is a figure explaining the operation | movement which hooks the structure | tissue around a perforation with a raising hook. It is the figure which pulled the suture and pulled the tissue hooked with the raising hook, and made the needle penetrate the tissue. It is a figure which shows the cross-sectional shape of the front-end | tip part of the suturing device which does not have a needle. FIG. 64 is a perspective view of the distal end portion of the suture instrument shown in FIG. 63. It is a figure which shows the high frequency knife as an example of the treatment tool used with a suturing device. It is a figure explaining a technique, Comprising: It is a figure which forms a small incision hole with a high frequency knife. It is the figure which looked at FIG. 67 from the side. It is a figure explaining the procedure which curves the outer sheath of a suture instrument and passes a small incision hole. It is the figure which pushed the anchor into the stomach and discharge | released. It is a figure for demonstrating the fastening order of many suture tools.

Explanation of symbols

13 Inner sheath (base, anchor holder)
16 Sewing tool 17, 121, 145, 190 Operation part (position operation device)
27,141 anchor 42 drilling 101,131,151,161,171,181 suture device 102,152,162 sheath (base)
103 treatment section (tip position changing mechanism)
112, 139, 163, 183, 193 Needle (anchor holder)
112A, 139A, 163A Sharp end 106 Second forceps piece (opening / closing member)
134 lumen 140 operation wire (tip position changing mechanism)
153, 184 First lumen 154 Second lumen 163A Tip 164 Curved portion (deflection mechanism)
168 Bending control member (shape memory alloy)
173 Balloon 182 Sheath (position operation device)
188 Raise hook

  Next, embodiments of the present invention will be described with reference to the drawings. In the following description of each embodiment, the same portions are denoted by the same reference numerals, and redundant descriptions are omitted.

[First Embodiment]
FIG. 1 shows an endoscope and a suture instrument used in this embodiment. The endoscope 1 (flexible endoscope) has an endoscope operation unit 2 that is operated by an operator. The endoscope operation unit 2 is connected to a control device by a universal cable 3 and is provided with various switches 4 and an angle knob 5. A flexible and long endoscope insertion portion 6 extends from the distal end of the endoscope operation portion 2. At the distal end of the endoscope insertion portion 6, an endoscope observation device (first observation device, hereinafter simply referred to as an observation device) 7 for acquiring an in-vivo image, an illumination device 8, a distal end opening of a channel 9, etc. Is provided. For the observation device 7, an imaging device having a CCD (Charge Coupled Device), an optical fiber, or the like is used. The illumination device 8 has an optical fiber that guides light from a light source. The channel 9 opens through the endoscope insertion portion 6 to the side portion 2 a of the endoscope operation portion 2. A lid 10 is attached to the opening of the side portion 2a. An insertion hole is formed in the lid 10, and a treatment tool such as a suture instrument 11 and an observation device are inserted into the channel 9 from the insertion hole.

As shown in FIGS. 1 to 3, in the suturing device 11, an inner sheath 13, which is a flexible base, is passed through a flexible outer sheath 12 so as to freely advance and retract. In the inner sheath 13, a hollow needle 14 having a sharp end is fixed to a distal end (hereinafter referred to as a tip) away from the hand. The needle 14 has a slit 15 extending from the tip in the longitudinal direction. A suture tool 16 is accommodated inside the outer sheath 12 and the needle 14. Each length of the outer sheath 12 and the inner sheath 13 is longer than the channel 9 of the endoscope 1. In the inner sheath 13, an operation unit 17 is attached to a proximal end (hereinafter referred to as a base end) on the proximal side.
The operation unit 17 includes a handle 19 that is slidable with respect to the operation unit main body 18. The proximal end of the pusher 20 is fixed to the handle 19. The pusher 20 extends into the needle 14 through the inside of the inner sheath 13. The distal end portion 21 of the pusher 20 is attached to the anchor 27 of the suture tool 16.

  As shown in FIG. 4, the suture tool 16 has a suture thread 25. The suture thread 25 is folded approximately in half, and a knot 31 is formed in the vicinity of the turning point. Further, the suture thread 25 is passed through a substantially triangular stopper 26 in a state where both ends are bundled. One anchor 27 is fixed to each end of the suture thread 25. The anchor 27 has a cylindrical shape, and the suture thread 25 is fixed to the approximate center in the longitudinal direction of the anchor 27. The stopper 26 has a hole 28 through which the suture thread 25 passes in the center in the longitudinal direction of the elongated plate member. Both end portions 29 in the longitudinal direction of the stopper 26 are folded back obliquely to sandwich the suture thread 25. Both end portions 29 in the longitudinal direction of the stopper 26 are cut into triangular sections 30. Both ends 29 of the stopper 26 are folded back diagonally so that the sections 30 intersect with each other, and the suture thread 25 is sandwiched therebetween. For this reason, the suture thread 25 does not fall out between the end portions 29. When the knot 31 of the suture thread 25 is pulled away from the stopper 26, both end portions 29 of the stopper 26 are slightly opened. Accordingly, the stopper 26 allows the suture 25 to move in this direction. On the other hand, when the end of the suture thread 25 on the anchor 27 side is pulled, the suture thread 25 tends to move in the direction indicated by the arrow in FIG. However, at this time, since both ends 29 of the stopper 26 are closed and the suture thread 25 is tightened, the suture thread 25 does not move.

  As shown in FIG. 3, the suture tool 16 is sequentially accommodated in the inner hole of the needle 14 in which the two anchors 27 function as anchor holding tools. The suture thread 25 is pulled out from the slit 15 of the needle 14. As shown in FIG. 2, the stopper 26 is accommodated at the distal end rather than the needle 14 in the outer sheath 12. The number of anchors 27 and the shape of the stopper 26 are not limited to the illustrated form.

Next, the suturing method of this embodiment will be described with reference mainly to FIGS. 5 to 12 are schematic diagrams for explaining the procedure, and the stomach is shown as an example of a luminal organ.
As shown in FIG. 5, the endoscope insertion portion 6 is inserted from the mouth (including natural openings in the living body, anus, nose, ears, etc.) of the patient 41 wearing the mouthpiece 40. When the distal end of the endoscope insertion portion 6 is bent with the angle knob 5, the perforation 42 can be confirmed from the inner side of the stomach 43 (the inner side of the luminal organ) with the observation device 7. As shown in FIG. 6, the observation device (second observation device) 50 is inserted into the channel 9 of the endoscope 1. The observation device 50 is, for example, a catheter with a camera at the tip. Further, the observation device 50 may be an elongated fiberscope.

  The distal end of the observation device 50 is advanced from the perforation 42 into the abdominal cavity 44, and the distal end of the observation device 50 is folded back with a wire or the like (not shown). A position (also referred to as a puncture position or a position where the needle 14 passes) around the perforation 42 by the observation device 50 and the position where the needle 14 passes is the abdominal cavity 44 side (in this embodiment, the side where the anchor 27 is placed). Observed) from the outside of the stomach 43 (also referred to as the body cavity side or abdominal cavity side of the luminal organ), and these tissues are connected to the needle 14 so that other tissues such as the small intestine and the liver are not punctured or sutured together. Make sure that is not in a position to pass.

  As shown in FIG. 7, while observing the stomach 43 from the abdominal cavity 44 side with the observation device 50, the suture device 11 is protruded and the tissue around the perforation 42 is punctured with the needle 14. When the tissue is punctured, the needle 14 is protruded from the outer sheath 12 as shown in FIG. In the process of projecting the needle 14, the stopper 26 accommodated on the distal side of the needle 14 is pushed out from the outer sheath 12 into the stomach 43. When the outer sheath 12 is fixed and the needle 14 is advanced, the needle 14 punctures the tissue. When the handle 19 on the hand side shown in FIG. 1 is pushed in, the pusher 20 moves forward, and the first anchor 27 is pushed out from the tip of the needle 14 to the abdominal cavity 44 as shown in FIG. When the first anchor 27 is pushed out and released, the pusher 20 is stopped and the needle 14 is withdrawn from the tissue. The first anchor 27 remains on the abdominal cavity 44 side. A suture 25 penetrates the tissue. The stopper 26 is in the stomach 43.

  Further, the needle 14 is inserted again at a position that is substantially symmetrical about the perforation 42 with respect to the position where the needle 14 was previously inserted. As with the first anchor 27, once the needle 14 has penetrated the tissue, the pusher 20 is advanced. The second anchor 27 is pushed out to the abdominal cavity 44. As shown in FIG. 9, when the needle 14 is pulled back, the second anchor 27 remains on the abdominal cavity 44 side, the suture 25 penetrates the tissue, and the two anchors 27 on the abdominal cavity 44 side sandwich the perforation 42. Released.

  Next, as shown in FIG. 10, the observation device 50 is pulled back into the stomach 43, and then the suture thread 25 is pulled to tighten the tissue with the anchor 27 and the stopper 26 to suture the perforation 42. When pulling the suture thread 25, for example, a forceps 60 as shown in FIG. 11 is used. The forceps 60 is passed through the channel 9 instead of the observation device 50. The forceps 60 has an outer sheath 61 having an outer diameter larger than that of the anchor 27, and an inner sheath 62 is passed through the outer sheath 61 so as to be able to advance and retract. A support member 63 is provided at the distal end of the inner sheath 62, and a pair of grip pieces 64 are supported on the support member 63 so as to be freely opened and closed.

  After gripping the knot 31 of the suture thread 25 of the suture tool 16 with the gripping piece 64, the outer sheath 61 is advanced and the distal end of the outer sheath 61 is pressed against the stopper 26. As shown in FIG. 12, when the outer sheath 61 further advances, the stopper 26 is pushed toward the wall of the stomach 43. Since the stopper 26 is configured to be movable in this direction, the stopper 26 moves toward the wall portion. Since the position of the pair of grip pieces 64 does not change, the stopper 26 advances relative to the suture thread 25. As a result, the distance between the stopper 26 and the anchor 27 is reduced. As a result, the tissue around the perforation 42 is drawn, and the perforation 42 is sutured by the suture thread 25. After the perforation 42 is sutured with the suture tool 16, the outer sheath 61 is retracted, the grip piece 64 is opened, and the suture thread 25 is released. The end of the stopper 26 can move in the direction in which the tissue is tightened with the suture thread 25, but works to tighten the suture thread 25 in the direction in which the suture thread 25 is loosened, so that the suture tool 16 is placed in the stomach 43. However, the suture thread 25 does not loosen.

  Here, if there is a small organ or colon lumen organ or other organs such as spleen / liver (hereinafter simply referred to as tissue) around the perforation 42 (position where the needle 14 is passed), the exclusion is performed. The device is inserted to pull other tissues away from the stomach 43. The exclusion device used at this time is illustrated in FIGS. 13 to 16. 13 is a rod 70 whose tip can be bent. When the rod 70 is bent, the other luminal organs are pushed away to form a space through which the needle 14 passes. The exclusion device shown in FIGS. 14 and 15 is a balloon catheter 71. When fluid is supplied from the proximal side and the balloon 73 at the distal end of the catheter 72 is inflated to push away other lumen organs, a space for passing the needle 14 is formed. The exclusion device shown in FIG. When another luminal organ is grasped by the forceps 74 and pulled away from the stomach 43, a space through which the needle 14 is passed is formed. You may provide the observation apparatus which has optical fiber and CCD in the front-end | tip part of these exclusion apparatuses. By providing the observation device, it is possible to exclude other tissues while observing the state of the abdominal cavity 44.

  In this embodiment, the perforation 42 is first observed from the stomach 43 with the observation device 7 of the endoscope 1, and then the perforation 42 is observed from the abdominal cavity 44 side with the observation device 50, and then the suture device 11 is perforated 42. The suture tool 16 is attached so as to penetrate the surrounding tissue, and the perforation 42 is sutured using the suture tool 16. Therefore, it is confirmed from the inner side of the stomach 43 (the insertion side of the needle 14) and the outer side (the penetration side of the needle 14 or the side where the anchor 27 is placed) that there is no other tissue around the perforation 42. After that, the perforations 42 can be sutured. As in the past, in the conventional suturing method using an endoscope, the opposite side could not be confirmed. In this embodiment, in the endoscopic suturing method, the presence of other tissues and the like can be easily and reliably confirmed, so that the procedure can be performed quickly.

A modification of this embodiment is shown in FIGS.
As shown in FIG. 17, two external sheaths 80 are attached to the outer periphery of the endoscope insertion portion 6. Each of the external sheaths 80 is passed through the suturing device 11 so as to freely advance and retract. One anchor 27 is accommodated in the needle 14 one by one. Two needles 14 can be pierced into the tissue simultaneously or in any order. As another example, two anchors 27 may be accommodated in one needle 14 with one external sheath 80. FIG. 18 shows an example in which one suturing device 11 is passed through two channels 9 of the endoscope insertion portion 6 one by one.

As shown in FIG. 19, the endoscope insertion portion 6 is inserted into the overtube 81. One lumen 82 is provided on the inner periphery of the overtube 81, and the suture device 11 is passed through the lumen 82. Alternatively, two lumens 82 may be provided on the inner periphery of the overtube 81, and one suture instrument 11 may be passed through each lumen 82.
As shown in FIG. 20, a channel 84 may be attached to the outer periphery of the endoscope insertion portion 6 and the observation device 50 may be passed through the channel 84. Further, the observation device 50 may be directly attached to the outer periphery of the endoscope insertion portion 6 without using the channel 84.

As shown in FIG. 21, an external channel 85 may be attached to the endoscope insertion portion 6 in parallel, and the suture device 11 may be passed through the channel 85. The channel 85 can be bent at the tip. When the perforation 42 is observed from the abdominal cavity 44 side as shown in FIG. 6, after the endoscope insertion portion 6 is sent to the abdominal cavity 44 through the perforation 42, the distal end portion of the endoscope insertion portion 6 is curved, Observation is performed with an observation device 7 provided in.
As shown in FIG. 22, the suture instrument 11 may be passed through a lumen 82 formed in the overtube 81. In this case, the periphery of the perforation 42 is observed from the abdominal cavity 44 side using the observation device 7 of the endoscope insertion portion 6.

[Second Embodiment]
In this embodiment, the same endoscope 1 and suture device 11 as those in the first embodiment are used. A duplicate description with the first embodiment is omitted.
The suturing method of this embodiment will be described. As shown in FIG. 5, the endoscope insertion portion 6 is inserted in the vicinity of the perforation 42, and the perforation 42 is observed from the stomach 43. Next, as shown in FIG. 23, the endoscope insertion portion 6 is sent out from the perforation 42 to the abdominal cavity 44, and the periphery of the perforation 42 is surrounded by the abdominal cavity 44 with the observation device (first observation device) 7 of the endoscope insertion portion 6. Observe from the side. When it is confirmed that there are no other luminal organs around the perforation 42, as shown in FIG. 24, the needle 14 of the suture instrument 11 is protruded from the endoscope insertion portion 6, and the needle 14 is inserted into the stomach 43 from the abdominal cavity 44 side. Insert into. Since the safety on the inner side of the stomach 43 is confirmed first, it is not necessary to observe the inside of the stomach 43 when the needle 14 is punctured. However, the puncture may be performed while observing the inside of the stomach 43 (side where the anchor 27 is placed) using another observation device. In this case, the puncture can be performed while observing the puncture position from both the inside of the stomach 43 and the abdominal cavity 44 side.

As shown in FIG. 25, the first anchor 27 is pushed into the stomach 43 from the tip of the needle 14. As shown in FIG. 26, when the two anchors 27 are released with the perforation 42 interposed therebetween, the suture instrument 11 is housed in the channel 9, and then the endoscope 1 is pulled back into the stomach 43.
As shown in FIGS. 27 and 28, the forceps 60 is passed through the channel 9 of the endoscope 1 returned into the stomach 43. The forceps 60 grips the knot 31 of the suture thread 25 on the abdominal cavity 44 side, and pulls the suture thread 25 and the stopper 26 into the stomach 43 through the perforation 42 into the stomach 43. As shown in FIG. 29, when the stopper 26 is pressed against the tissue with the outer sheath 61, the tissue is tightened by the suture tool 16 and the perforation 42 is sutured.

  In this embodiment, after observing the inside of the stomach 43 using the endoscope 1, the endoscope 1 is moved to the outside of the stomach 43, and another tissue is placed around the perforation 42 by the observation device 7. It is confirmed from the abdominal cavity 44 side that there is no such thing. Thereafter, with the endoscope 1 being passed through the perforation 42, the tissue 14 is punctured from the outside with the needle 14, the suture tool 16 is attached, and the perforation 42 is sutured. Accordingly, when the endoscope 1 is sutured, it is possible to easily prevent other tissues from being caught.

[Third Embodiment]
In this embodiment, the same endoscope 1 and suture device 11 as those in the first embodiment are used. A duplicate description with the first embodiment is omitted.
The suturing method of this embodiment will be described. As shown in FIG. 5, the endoscope insertion portion 6 is inserted in the vicinity of the perforation 42, and the perforation 42 is observed from the stomach 43. Next, as shown in FIG. 23, the endoscope insertion portion 6 is sent out from the perforation 42 to the abdominal cavity 44, and the periphery of the perforation 42 is surrounded by the abdominal cavity 44 with the observation device (first observation device) 7 of the endoscope insertion portion 6. Observe from the side. When it is confirmed that there is no other tissue around the perforation 42 (position where the needle 14 passes, puncture position or position where the anchor 27 is placed), the endoscope insertion portion 6 is pulled back into the stomach 43. Next, the suture instrument 11 passed through the channel 9 is projected. As shown in FIG. 30, the distal end portion of the suture instrument 11 is sent out from the perforation 42 to the abdominal cavity 44. Then, the distal end portion of the suturing device 11 is curved and is directed to the outside of the stomach 43 by the abdominal cavity 44 and around the perforation 42.

  As shown in FIG. 31, the suture instrument 11 causes the needle 14 to protrude from the outer sheath 12, and the needle 14 penetrates the tissue around the perforation 42 from the abdominal cavity 44 side toward the stomach 43. When the needle 14 is protruded from the outer sheath 12, it is preferable that the stopper 26 enters the stomach 43. As shown in FIG. 32, when the needle 14 penetrates the tissue, the first anchor 27 is pushed out to the inside of the stomach 43 and released. As shown in FIG. 33, when the two anchors 27 are placed in the stomach 43 so as to sandwich the perforation 42, the suture device 11 is returned to the stomach 43 and accommodated in the channel 9. Then, as shown in FIG. 34, when the forceps 60 are passed through the channel 9 and the tissue is tightened with the suturing tool 16 using the forceps 60, the perforation 42 is sutured. The tightening method is the same as in the second embodiment.

  In this embodiment, the internal side and the external side of the stomach 43 are observed in order with the observation device 7 of the endoscope 1 to confirm that there is no other tissue around the perforation 42, and the endoscope 1 is While returning to the inside of the stomach 43, the tissue was penetrated by the needle 14 from the outside of the stomach 43. Therefore, when the endoscope 1 is sutured, other tissues can be easily prevented from being caught.

Here, a modification of this embodiment will be described. As shown in FIG. 23, after observing the outside of the stomach 43 using the observation device 7 of the endoscope insertion section 6, the endoscope insertion section 6 is pulled back into the stomach 43. Thereafter, as shown in FIG. 35, the suture instrument 11 is projected from the endoscope insertion portion 6 in the stomach 43, and the needle 14 is inserted from the inside of the stomach 43 toward the outside. When the anchor 27 is placed on the outer side of the stomach 43, the perforation 42 is sutured by tightening the suture tool 16 as shown in FIGS. In this case, when the endoscope 1 is used for suturing, the involvement of other tissues or the like is easily prevented.
As shown in FIG. 36, a channel 91 may be attached to the outer periphery of the endoscope insertion portion 6, and the suture instrument 11 may be passed through the channel 91. Further, the suture instrument 11 may be directly attached in parallel to the outer periphery of the endoscope insertion portion 6. The distal end portion of the suturing device 11 is configured to be independently bendable.

[Fourth Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIGS. 37 and 38, in the suturing device 101, a treatment portion 103 that is a tip position changing mechanism is fixed to a tip that is a distal end of a sheath 102 that is a flexible base. The treatment portion 103 has a support member 104 fixed to the sheath 102, and a first forceps piece 105 extends integrally at the distal end of the support member 104. Further, a second forceps piece 106 (opening / closing member) is rotatably supported by the support member 104 with a pin 107. The second forceps piece 106 is connected to the link mechanism 108 by pulling the proximal end portion of the second forceps piece 106 into the support member 104. The link mechanism 108 is connected to a forceps wire 109 that is passed through the sheath 102 so as to freely advance and retract. When the forceps wire 109 is advanced and retracted, the second forceps piece 106 rotates with respect to the support member 104, and the pair of forceps pieces 105 and 106 can be opened and closed. An operation unit 17 (see FIG. 1) that performs an opening / closing operation is fixed to the proximal end of the sheath 102. The first forceps piece 105 may also be configured to open and close.

In each of the pair of forceps pieces 105 and 106, slits 110 and 111 are formed along the length direction. A hollow needle 112 is disposed in the slit 111 of the second forceps piece 106. An end portion 112A on the distal end side of the needle 112 functioning as an anchor holder is disposed at the distal end portion of the second forceps piece 106 and is rotatably supported by the second forceps piece 106 with a pin 113. The proximal end side of the needle 112 is disposed on the proximal end side of the slit 111 and has a sharp end 112B. In the state shown in FIGS. 37 and 38, the entire needle 112 is accommodated in the slit 111 of the second forceps piece 106 in the closed state. The needle 112 is substantially parallel to the longitudinal direction of the sheath 102, and the sharp end 112A is directed to the proximal end side of the sheath 102, that is, the proximal end side.
Two anchors 27 of the suturing tool 16 are accommodated inside the needle 112. In the needle 112, a slit 112C extends from the sharp end 112B toward the end 112A with a predetermined length, and the suture thread 25 is drawn out from the slit 112C.

  A pusher sheath 115 is connected to the end 112 </ b> A side of the needle 112. The pusher sheath 115 passes through the slits 110 and 111 of the pair of forceps pieces 105 and 106, extends along the sheath 102, and is drawn out to the hand side. A pusher 20 that pushes out the anchor 27 of the suture tool 16 is passed through the pusher sheath 115 so as to be able to advance and retreat.

  As shown in FIG. 39, in the suturing device 101, a position operating device (operation unit 121) for operating the distal end position changing mechanism is used by being pulled out from the endoscope 1. The operation unit 121 includes an operation unit main body 122 to which the proximal end portion of the sheath 102 is fixed. The operation portion main body 122 is provided with a finger-holding ring 122A, and a slider 123 is attached to the distal end side of the ring 122A so as to be movable forward and backward in the length direction of the sheath 102. A forceps wire 109 is fixed to the slider 123, and the pair of forceps pieces 105 and 106 can be opened and closed by moving the slider 123 forward and backward with respect to the operation portion main body 122. Further, the pusher sheath 115 is passed through the operation portion main body 122 so as to be able to advance and retract. The pusher sheath 115 is pulled out from a position separated from the slider 123 when the operation portion main body 122 branches into two forks. A pusher sheath knob 124 is provided at the end of the pusher sheath 115 pulled out from the operation portion main body 122 so that the operator can easily grasp it. The pusher 20 is further pulled out from the pusher sheath knob 124. A pusher knob 125 is provided at the end of the pusher 20 so that the operator can easily grasp it.

  When the perforation is sutured, as shown in FIG. 5, the endoscope insertion portion 6 is inserted in the vicinity of the perforation 42 and the perforation 42 is observed from the stomach 43. Next, as shown in FIG. 23, the endoscope insertion portion 6 is sent out from the perforation 42 to the abdominal cavity 44, and the periphery of the perforation 42 is surrounded by the abdominal cavity 44 with the observation device (first observation device) 7 of the endoscope insertion portion 6. Observe from the side. When it is confirmed that there is no other tissue around the perforation 42 (a position where the needle 112 passes, a puncture position, or a position where the anchor 27 is placed), the endoscope insertion portion 6 is pulled back into the stomach 43.

  With the pair of forceps pieces 105 and 106 closed, the treatment portion 103 is passed through the perforation 42 and protrudes outside the organ to be sutured (for example, the stomach 43). The slider 123 of the operation unit 121 is pushed in to open the second forceps piece 106 with respect to the first forceps piece 105. The second forceps piece 106 including the needle 112 moves in a direction intersecting the axis of the sheath 102. Further, the pusher sheath knob 124 is grasped to push out the pusher sheath 115. As shown in FIG. 40, the needle 112 pushed by the pusher sheath 115 rotates around the pin 113 and exits from the slit 111 of the second forceps piece 106, and the sharp end 112B of the needle 112 becomes the sheath 102. Toward the proximal side of the sheath 102, ie, the outer surface of the tissue around the perforation 42.

  When the entire end of the suture instrument 101 is retracted after the sharp end 112B of the needle 112 is aligned with the position to be inserted, the needle 112 penetrates the stomach 43 from the outside to the inside. As shown in FIG. 41, the pusher knob 125 is held and the pusher 20 is pushed in to push out the first anchor 27 from the needle 112. Thereafter, when the entire suture instrument 101 is advanced, the needle 112 is removed from the tissue. The suture 25 penetrates the tissue and the first anchor 27 remains in the stomach 43.

Next, the suturing device 101 is rotated about the axis, and the needle 112 is moved to the opposite side of the place where the suture thread 25 is passed around the perforation 42. When the suturing device 101 is retracted again, the needle 112 penetrates the stomach 43 from the outside toward the inside. As shown in FIG. 42, the pusher 20 is further pushed in to push out the second anchor 27 from the needle 14. After the needle 112 is removed from the tissue, the pusher sheath knob 124 is grasped to retract the pusher sheath 115, and the needle 112 is accommodated in the slit 111 of the second forceps piece 106. Further, the slider 123 is pulled to close the pair of forceps pieces 105 and 106.
When the suturing device 101 is pulled back into the stomach 43 from the perforation 42, the perforation 42 is closed by tightening the suture tool 16 with the forceps 60 in the same manner as in FIGS.

  According to this embodiment, in the suturing method in which the needle 112 is penetrated from the outside to the inside of the tissue, the needle 112 can be surely penetrated. Since the suturing tool 16 can be detained only by the opening / closing operation and the pusher sheath 115 and the pusher 20 being advanced and retracted, the operation is simple. The pair of forceps pieces 105 and 106 can also be used for grasping tissue.

[Fifth Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIG. 43, the suturing device 131 has a lumen 134 in a sheath 132 which is a flexible base, and an adsorption surface 132A is provided so as to close the tip of the lumen 134. An adsorbing tool 136 is passed through the lumen 134 so as to freely advance and retract. The tip portion 136A of the suction tool 136 is manufactured from a magnetic material.

A support portion 137 extends substantially along the longitudinal direction at the distal end of the sheath 132 so as to avoid the opening of the lumen 134. A hollow needle 139 is rotatably supported by a pin 138 at the tip of the support portion 137. The needle 139 is elongated from the end portion on the distal end side supported by the pin 138, and the other end portion on the proximal end side is a sharp end portion 139A. In the initial state, the needle 139 is substantially parallel to the sheath 132 and the sharp end 139A is directed to the proximal end side of the sheath 132, that is, the proximal end side.
An operation wire 140 constituting a tip position changing mechanism is fixed to the sharp end 139A of the needle 139. The operation wire 140 is pulled out to the hand side through the tip of the support portion 137. When the operation wire 140 is pulled, the needle 139 rotates about the pin 138 as a fulcrum, and rises as indicated by a virtual line. The operation wire 140 has a predetermined hardness. When the operation wire 140 is pushed in, the operation wire 140 is accommodated so that the needle 139 is substantially along the support portion 137, that is, substantially parallel to the longitudinal direction of the sheath 132. . Note that if the support wire 137 is provided with a groove and the operation wire 140 is passed through the groove, the operation wire 140 is prevented from falling off.

  An anchor 141 of the suture tool 16 is accommodated in the needle 139. The suture tool 16 has the same configuration as the suture tool 16 except that each of the two anchors 141 is made of a permanent magnet. The anchor 141 is accommodated in the needle 139 so that the same magnetic poles face each other. In FIG. 43, the S poles are opposed to each other.

  As shown in FIG. 44, an operation unit 145 that is a position operation device for the suturing device 131 has an operation unit main body 146 to which the sheath 132 is fixed. The operating portion main body 146 is provided with a finger-hooking ring 146A, and a slider 147 that can be moved forward and backward in the length direction of the sheath 132 is attached. An operation wire 140 is fixed to the slider 147, and when the slider 147 is advanced and retracted, the needle 136 can be accommodated and deployed. Further, the operation unit main body 146 is bifurcated, and the suction tool 136 is pulled out to a position away from the slider 147. A knob 148 is formed at the end of the suction tool 136 so that the operator can easily grasp it.

  The procedure for suturing the perforation 42 with the suturing device 131 is to observe the inside and the outside of the stomach 43 in order as in the third embodiment. When penetrating the needle 139, the treatment portion 133 is protruded outward from the perforation 42. When the operation wire 140 is pulled by operating the slider 147 of the operation unit 145, the needle 139 is tilted and deployed in a direction intersecting the axis of the sheath 132 around the pin 138. As shown in FIG. 45, the sharp end 139 A of the needle 139 is directed toward the tissue, ie, the proximal end of the sheath 132. When the entire suture instrument 131 is retracted, the needle 139 penetrates the stomach 43 from the outside toward the inside. When the suction tool 136 is pushed in by grasping the knob 148 pulled out from the operation unit 145, the suction tool 136 is brought closer to the needle 139 from the inside of the stomach 43 as shown in FIG. A suction force acts between the distal end portion 136A of the suction tool 136 and the first anchor 141 to attract the anchor 141 to the suction surface 132A. As shown in FIG. 47, the first anchor 141 is taken out from the needle 139. It is. After the first anchor 141 is attracted to the suction surface 132A, the first anchor 141 is detached from the suction surface 132A by retracting the suction tool 136 within the lumen 134, as shown in FIG. be able to.

  When the entire suture instrument 131 is advanced to remove the needle 139 from the tissue, the needle 139 is rotated around the axis and moved to the opposite side around the perforation 42. Similarly, the suturing device 131 is retracted and the stomach 43 is penetrated from the outside to the inside by the needle 139. The second anchor 141 is pulled out by bringing the suction tool 136 closer. The entire suture instrument 131 is advanced to remove the needle 139 from the tissue. After the needle 139 is moved along the support portion 137, the suture instrument 131 is removed from the endoscope 1. As in FIGS. 28 and 29, the perforation 42 is closed by tightening the suture tool 16 with the forceps 60.

  According to this embodiment, in the suturing method in which the needle 139 is penetrated from the outside to the inside of the tissue, the needle 139 can be reliably penetrated. Since only the rotation operation of the needle 139 and the advancement / retraction of the suction tool 136 are required, the operation is simple.

[Sixth Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIG. 49, the suture instrument 151 has two lumens 153 and 154 formed substantially parallel to the longitudinal direction in a sheath 152 which is a flexible base. The first lumen 153 has an opening 153A at the tip, and a needle 155 is passed through in a freely reciprocating manner. In the second lumen 154, the distal end opening 154A is formed on the proximal end side with respect to the distal end opening 153A of the first lumen 153.

  Needle 155 is hollow and elongated and is manufactured from a shape memory alloy. The sharp end 155A of the needle 155 protrudes from the distal end opening 153A of the first lumen 153, is elastically deformed into a substantially U shape, and is inserted into the second lumen 154 so as to be freely inserted and removed from the distal end opening 154A. That is, the sharp end 155 </ b> A is disposed substantially parallel to the sheath 152 and toward the proximal end of the sheath 152. The needle 155 is an anchor holding tool in which two anchors 27 (not shown in FIG. 49) of the suturing tool 16 are accommodated in a sharp end 155A. The anchor 27 can be pushed out by the pusher 20 passed through the needle 155. Note that the shape of the needle 155 is memorized so that the sharp end portion 155A is curved toward the base end side. As shown in FIG. 50, when the needle 155 is pulled out from the second lumen 154, the curved needle 155 is deployed in a direction intersecting the axis of the sheath 152. At this time, the width WD1 of the outer shape of the needle 155 is larger than the outer diameter WD2 of the sheath 152. In this embodiment, the curved portion of the needle 155 is the tip position changing mechanism, and the proximal end of the needle 155 is the position operating device.

  The procedure for suturing the perforation 42 with the suturing device 151 is to observe the inside and the outside of the stomach 43 in order as in the third embodiment. As shown in FIG. 51, when penetrating the needle 155, the suturing device 151 is projected outward from the perforation 42 to the position where the distal end opening 154A of the second lumen 154 is formed. When the needle 155 is pushed into the sheath 152, the sharp end 155A of the needle 155 comes out of the second lumen 154. As shown in FIG. 52, the needle 155 is deployed by its own restoring force, and the sharp end 155A moves from a position substantially parallel to the sheath 152 to a position offset from the axis of the sheath 152, and around the perforation 42. Directed to the organization. When the entire suture instrument 151 is retracted, the needle 155 penetrates the stomach 43 from the outside to the inside. When one anchor 27 is pushed out by the pusher 20 and released, the suture instrument 151 is advanced to remove the needle 155 from the tissue, and the tissue opposite to the perforation 42 is similarly penetrated. When the second anchor 27 is pushed out by the pusher 20 and released, the needle 155 is removed from the tissue, and the suture device 151 is recovered. As in FIGS. 28 and 29, the perforation 42 is closed by tightening the suture tool 16 with the forceps 60.

According to this embodiment, the suturing device 151 can be easily passed through the endoscope 1 and the perforation 42 by curving the shape-stored needle 155 and storing it in the second lumen 154. When the needle 155 is deployed, the operation is easy because it is only necessary to move it forward.
In place of the anchor 27 and the pusher 20, the anchor 141 and the suction tool 136 of the fourth embodiment may be used.

[Seventh Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIG. 53, in the suturing device 161, a hollow needle 163 that is an anchor holder is passed through a sheath 162 that is a flexible base so as to freely advance and retract. The needle 163 has flexibility, and is provided with a sharp end 163 </ b> A that penetrates the tissue after a curved portion 164 serving as a deflection mechanism is provided at a portion protruding from the sheath 162. The bending portion 164 has a configuration in which a plurality of bending pieces 165 are connected in the longitudinal direction. Each bending piece 165 is formed of a hollow member, and each base end portion and distal end portion thereof are rotatably attached to other bending pieces 165 adjacent to each other by pins 167. The pins 167 that connect the curved pieces 165 to each other are all arranged in parallel. Further, a bending control member 168 made of a shape memory alloy is bridged between the bending pieces 165. Each bending control member 168 is disposed at the same position in the circumferential direction viewed from the center line of the needle 163, and each of them is wound in a coil shape in the initial state. That is, in the initial state, the needle 163 is disposed substantially parallel to the axis of the sheath 162, and the sharp end 163A is directed toward the distal end of the sheath 162. The bending control member 168 can be restored to a substantially linear shape by energization, heat generation, or body temperature. For this reason, the position operating device of the suturing device 161 is a device (not shown) that energizes or generates heat to the bending control member 168, or the bending control member 168 itself when it is restored at body temperature.

The procedure for suturing the perforation 42 with the suturing device 161 observes the inside and the outside of the stomach 43 in the same manner as in the third embodiment.
The needle 163 is passed through the perforation 42 in a state where the bending control member 168 is contracted in a coil shape, that is, in a state where the needle 163 is arranged so as to be substantially parallel to the sheath 162. When the bending portion 164 protrudes outward from the perforation 42, an electric current is supplied to the bending control member 168 or heated. Each bending control member 168 is restored and extended, and as shown in FIG. 54, the adjacent bending pieces 165 and needles 163 are pushed in a certain direction. As a result, the curved portion 164 is curved in a substantially U shape, and the sharp end 163A of the needle 163 is directed from the distal end direction of the sheath 162 to the proximal end side, that is, the tissue.
As the needle 163 advances and retreats, the stomach 43 is pierced from the outside toward the inside, and the first anchor 27 is pushed out from the needle 163 by the pusher 20. When the anchor 27 is pushed out and released to the inside of the stomach 43 through the suture thread 25 at two positions across the perforation 42, the suture instrument 161 is removed from the endoscope 1, and the suture tool is clamped with the forceps 60 as in FIGS. 16 is tightened to close the perforation 42.

According to this embodiment, since the shape memory alloy is used to bend a part of the bending portion 164 of the needle 163 in the body, the needle 163 is handled in a straight shape when the suturing device 161 is removed. Work can be done easily.
Here, the bending control member 168 made of a shape memory alloy is not limited to a shape in which a coil is wound in a coil shape. Further, the bending control member 168 may be a plate-like member that is bent by energization or the like. A plate-like bending control member 168 can be used together with the bending piece 165 or instead of the bending piece 165.

[Eighth Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIG. 55, in the suturing device 171, the needle 14 is passed through a sheath 172 that is a flexible base so as to freely advance and retract. A balloon 173 as a deflection mechanism is integrally formed at the distal end portion of the sheath 172. The balloon 173 is provided only on a part of the outer peripheral surface and does not extend over the entire circumference, so that the balloon 173 is offset from the center line of the needle 14 passing through the center of the sheath 172.
Therefore, when a fluid supply device (position operation device) is attached to the end of the lumen (not shown) with the sharp end of the needle 14 protruding outward from the perforation 42, and the fluid is supplied, FIG. 56 and FIG. As shown, the balloon 173 is inflated and the sheath 172 is pushed by the balloon 173 to bend. Since the balloon 173 is arranged so that the sheath 172 is curved in a substantially U shape, the sharp end of the needle 14 is directed from the distal direction of the sheath 172 to the proximal end side, that is, the tissue, and from the outside. It becomes possible to penetrate inside. Here, as shown in FIG. 58, by inflating the balloon 173, the outer organ 175 around the tissue to be sutured is removed.

  In this embodiment, by inflating the balloon 173, the needle 14 can be bent in a substantially U shape, so that the tissue can be penetrated from the outside to the inside with a simple operation. Further, since the balloon 173 excludes the outer organ 175, it can be easily sutured even in a location close to the outer organ 175.

[Ninth Embodiment]
In this embodiment, a suturing device suitable for the suturing method in the third embodiment will be described.
As shown in FIG. 59, in the suturing device 181, a needle 183 is passed through a sheath 182 that is a flexible base so as to freely advance and retract. Two lumens 184 and 185 are formed in the sheath 182 substantially in parallel. Since the distal end that is the distal end of the sheath 182 is formed with a curved portion 182A that functions as a deflection mechanism, the first lumen 184 is curved by approximately 90 ° to form an opening 184A on the side portion. . A hollow needle 183 that is an anchor holder is passed through the first lumen 184 so as to freely advance and retract. Needle 183 is preferably made of a superelastic alloy. Even if it passes through the lumen located at the curved portion 182A, permanent deformation does not occur.

  The second lumen 185 is bent by approximately 90 ° at the curved portion 182A to form an opening 185A on the same side in the circumferential direction on the proximal end side with respect to the first lumen 185. An operation wire 186 is passed through the second lumen 185 so as to freely advance and retract. The operation wire 186 is fixed to the distal end portion of the lifting hook 188 that is rotatably supported by the sheath 182 by a pin 187 on the proximal end side from the opening 185A. The lifting hook 188 can be accommodated in a concave portion 189 formed in the sheath 182 so that the distal end thereof is directed toward the hand side, and when the operation wire 186 is pulled, the lifting hook 188 expands outward as indicated by an imaginary line.

  As shown in FIG. 60, an operation unit 190 that is a position operation device for the suturing device 181 includes a proximal end portion 182 </ b> B of a sheath 182. When the proximal end portion 182B is grasped and advanced and retracted, the entire suture device 181 can be advanced and retracted. A needle 183 and an operation wire 186 are pulled out separately from the base end portion 182B. An operation unit main body 191 is fixed to the needle 183. The operation unit main body 191 is provided with a finger ring 191A, and a slider 192 that can be moved back and forth in the length direction is attached. A pusher 20 is fixed to the slider 192. A knob 193 is formed at the end of the operation wire 182 so that the operator can easily grasp it.

  As shown in FIG. 61, when the perforation 42 is sutured, the needle 183 is disposed on the proximal end side of the first lumen 184, that is, the sharp end of the needle 183 is accommodated in the sheath 182 in a substantially parallel state. , Project outside the perforation 42. When the lifting hook 188 is fed to the outside through the perforation 42, the operating wire 186 is pulled to open the lifting hook 188. When the tissue around the perforation 42 is hooked on the tip of the lifting hook 188 and the entire suture device 181 is retracted, the tissue hooked on the lifting hook 188 is drawn toward the endoscope 1. As shown in FIG. 62, since the orientation of the opening 184A of the first lumen 184 and the pulled tissue intersect, the sharp end is moved closer to the distal direction of the sheath 182 when the needle 183 is advanced. Since it is deflected by approximately 90 ° in the direction toward the distal end, the tissue hooked on the lifting hook 188 can be penetrated.

  When the needle 183 is pierced and the first anchor 27 is pushed out and released, the needle 183 is removed and then the entire suture instrument 181 is advanced. The lift hook 188 is disengaged from the tissue. Similarly, with respect to the tissue on the opposite side as viewed from the perforation 42, the needle 183 is penetrated while pulling up the tissue with the lifting hook 188, and the second anchor 27 is pushed out. After the suturing device 181 is removed from the endoscope 1, the perforation 42 is closed by tightening the suturing tool 16 with the forceps 60 as in FIGS. 28 and 29.

According to this embodiment, since the needle 183 is pierced after the tissue is pulled by the lifting hook 188, the suture tool 16 can be placed with a simple operation. Further, by pulling the tissue with the lifting hook 188, the position when the needle 183 is inserted and the process of penetrating the needle 183 can be reduced without bending the needle 183 by approximately 180 ° as in the other embodiments. It can be observed with the endoscope 1. Instead of hooking the lifting hook 188 on the tissue, the tissue may be sandwiched between the lifting hook 188 and the sheath 182.
Here, the bending portion 182A at the distal end of the sheath 182 may be an angle at which the needle 183 can penetrate the tissue by cooperating with the lifting hook 188, and may be an acute angle greater than 0 ° and 90 ° or less. Therefore, the pusher 20 can be advanced and retracted and the anchor 27 can be pushed out with a light force as compared with a case where the pusher 20 is bent approximately 180 °.

[Ninth Embodiment]
In this embodiment, a suturing device suitable for the suturing method according to the third embodiment will be described in which the anchor is not accommodated in the needle.
As shown in FIGS. 63 and 64, the suturing device 201 has a flexible base inside the flexible outer sheath 12, and an inner sheath 13 that functions as an anchor holder is passed through in a freely reciprocating manner. Yes. The inner sheath 13 is opened at the tip, and a slit 15 is provided in the side portion along the length direction. Inside the inner sheath 13, two anchors 27 of the suture tool 16 are accommodated side by side. The pusher 20 is brought into contact with the anchor 27 on the proximal end side. In addition, the operation part of this suturing device 210 can use the thing similar to the operation part 17 shown in FIG.

  In the suturing device 201, a treatment tool such as a high-frequency knife is used to pass the suture thread 25 of the suturing tool 16. FIG. 65 shows a high-frequency knife that is an example of a treatment instrument. The high-frequency knife 211 has a long flexible sheath 212, and an operation portion 213 is provided at the proximal end of the sheath 212. The operation unit 213 is provided with a slider 215 that can move forward and backward with respect to the operation unit main body 214 and a finger ring 214A. The end of the long electrode 216 is fixed to the slider 215. The electrode 216 is electrically connected to the electrode cable 217 via a terminal 215 </ b> A provided on the slider 215. The electrode cable 217 is connected to a high frequency power source (not shown). The electrode 216 extends to the distal end of the sheath 212 through the sheath 212 movably. When the slider 215 is retracted, the electrode 216 is accommodated in the sheath 212. When the slider 215 is advanced, the tip portion of the electrode 216 protrudes from the sheath 212.

  As shown in FIG. 66, when the perforation 42 is sutured, a small incision hole 220 is formed from the inside to the outside of the tissue around the perforation 42 through the high-frequency knife 211 through the channel 9 of the endoscope 1. Specifically, when the planned position for forming the small incision hole is confirmed, the slider 215 is advanced to project the electrode 216 from the sheath 212. A high frequency current is supplied from a high frequency power source and the tip of the electrode 216 is pressed to a predetermined position to form a small incision hole 220. When the small incision holes 220 are formed at two locations across the perforation 42, the supply of high-frequency current is stopped. After the electrode 216 is accommodated in the sheath 212, the high-frequency knife 211 is pulled out from the endoscope.

Next, an operation of placing the anchors 27 one by one through the suture thread 25 in the small incision holes 220 is performed. The suture instrument 201 is passed through the endoscope 1 and the inner sheath 13 is protruded from the outer sheath 12. At this time, the inner sheath 13 abuts against the stopper 26 over a wide area, and pushes the stopper 26 from the outer sheath 12 into the stomach 43.
As shown in FIG. 68, the outer sheath 12 of the suture instrument 201 is protruded into the abdominal cavity 44 through the perforation 42. The tip of the outer sheath 12 is bent, and the outer sheath 13 is directed from the direction toward the distal end of the suture instrument 201 toward the proximal end, that is, toward the tissue. Further, the inner sheath 12 is advanced to pass the small incision hole 220 from the outside toward the inside. Since the inner sheath 13 protrudes from the abdominal cavity 44 into the stomach 43, when the pusher 20 is advanced as shown in FIG. 69, the first anchor 27 is pushed out and released into the stomach 43. Thereafter, the inner sheath 13 is pulled out from the small incision hole 220. The suture thread 25 penetrates the small incision hole 220. Further, the inner sheath 13 is similarly passed through the small incision hole 220 on the opposite side. When the second anchor is released inside the stomach 43, the suture instrument 201 is pulled back, and the suture thread 25 is passed through the small incision hole 220. When the suture instrument 201 is pulled back into the stomach 43 and the suture tool 16 is tightened in the same manner as in the above-described embodiment, the perforation 42 is sutured.

  Since the suturing device 201 does not have a needle, the contact surface with the stopper 26 is wide, and the stopper 26 can be easily and reliably pushed out of the outer sheath 12.

The present invention can be widely applied without being limited to the above embodiments.
For example, in each of the suture devices according to the fourth to eighth embodiments, an anchor holding tool as shown in the ninth embodiment is used instead of the needle, and a small tool formed by another treatment tool is used. The anchor may be released after passing the anchor holder through the incision hole.
The endoscope 1 may be inserted from the anus into the large intestine, which is an example of a luminal organ. In this case, perforations such as the large intestine are sutured. Although it has been described that the perforation 42 has already been formed, the perforation 42 may be formed using the endoscope 1 and then the procedures of the above-described embodiments may be performed. In this case, the endoscope 1 is inserted into the stomach 43 through a natural opening, and the planned incision portion is confirmed with the observation device 7 provided at the distal end of the endoscope insertion portion 6. Thereafter, a planned incision is cut through the channel 9 of the endoscope 1 through a high-frequency knife or the like to form a perforation 42.

  When the perforation 42 is sutured with three or more suture tools 16, such as when making a large incision in the stomach 43, the plurality of suture tools 16 may be tightened in order from the end. For example, in the example of FIG. 70, the suture tool 16a, the suture tool 16b, the suture tool 16c, the suture tool 16d, and the suture tool 16e are tightened in this order. The perforation 42 is sewn from the end, and the size of the perforation 42 can be gradually reduced, so that the suturing is facilitated. Alternatively, the suture tool 16 in the middle of the plurality of suture tools 16 may be tightened first, and then the suture tool 16 positioned in the middle of the central tightened suture tool 16 and the suture tool 16 at the end may be tightened. In the example of FIG. 70, the suturing tool 16c is first tightened, then the suturing tool 16b and the suturing tool 16d are tightened, and finally the suturing tool 16a and the suturing tool 16e are tightened. Since the middle position of the opening is always stitched, the shift of the stitching position is reduced.

  The suturing method and suturing device according to the present invention can be suitably used for medical purposes.

Claims (11)

A suture instrument that is inserted into the body and connected to a suture that sutures a perforation and releases an elongate anchor that is placed in the tissue;
A flexible base extending from the proximal proximal end to the distal end introduced into the tissue;
An anchor retainer disposed at a distal end of the base, capable of accommodating a plurality of the anchors therein, and a tip for discharging the anchor being substantially oriented toward the proximal end of the base;
A tip position changing mechanism that is provided to change the tip position of the anchor holder and moves the anchor holder in a direction that intersects the longitudinal axis of the base;
A position operating device for operating the tip position changing mechanism on the hand side and operating the tip position of the anchor holder;
A suturing device.   The suturing device according to claim 1, wherein the tip position changing mechanism changes the position by moving the anchor holder to a position offset from an axial line in the length direction of the base.   The suturing device according to claim 1, wherein the tip position changing mechanism changes the position by inclining the anchor holder with respect to an axis in the length direction of the base.   The suturing device according to any one of claims 1 to 3, wherein the anchor holder is a needle having a sharp end at a tip.   The suture instrument according to any one of claims 1 to 3, wherein a distal end of the anchor holder is formed of a hollow needle, and the anchor is disposed in the needle.   The anchor is further provided with an adsorbing device that adsorbs magnetic force, and the adsorbing device is disposed so as to freely advance and retreat along the base. Both the anchor and the adsorbing device are manufactured from a magnetic material, one of which is a magnet. The suturing device according to any one of claims 1 to 5, wherein: A suture instrument that is inserted into the body and connected to a suture that sutures a perforation and releases an elongate anchor that is placed in the tissue;
A flexible base extending from the proximal proximal end to the distal end introduced into the tissue;
An anchor holder disposed at the distal end of the base, capable of accommodating a plurality of the anchors therein, and having a tip for releasing the anchor disposed on the distal end side of the base;
A deflection mechanism provided to deflect the tip position of the anchor holder, and deflects the tip of the anchor holder in a direction from the distal end toward the proximal end of the base;
A position operating device for operating the deflection mechanism on the hand side and operating the tip position of the anchor holder;
A suturing device.   The suturing device according to claim 7, wherein the tip position changing mechanism changes the position by inclining the anchor holder with respect to an axis in the length direction of the base.   The suturing device according to claim 7 or 8, wherein the anchor holder is a needle having a sharp end at a distal end.   The suture instrument according to claim 7 or 8, wherein a distal end of the anchor holder is formed of a hollow needle, and the anchor is disposed in the needle.   The anchor is further provided with an adsorbing device that adsorbs magnetic force, and the adsorbing device is disposed so as to freely advance and retreat along the base. Both the anchor and the adsorbing device are manufactured from a magnetic material, one of which is a magnet. The suturing device according to any one of claims 7 to 10, which is:

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