JPS6471899A - Steroid compound - Google Patents

Steroid compound

Info

Publication number
JPS6471899A
JPS6471899A JP22805587A JP22805587A JPS6471899A JP S6471899 A JPS6471899 A JP S6471899A JP 22805587 A JP22805587 A JP 22805587A JP 22805587 A JP22805587 A JP 22805587A JP S6471899 A JPS6471899 A JP S6471899A
Authority
JP
Japan
Prior art keywords
17beta
expressed
formula
17alpha
ethynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP22805587A
Other languages
Japanese (ja)
Inventor
Kiyoshi Watanabe
Hideaki Kataoka
Kuniaki Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeon Corp
Original Assignee
Nippon Zeon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zeon Co Ltd filed Critical Nippon Zeon Co Ltd
Priority to JP22805587A priority Critical patent/JPS6471899A/en
Priority to EP88114770A priority patent/EP0306969B1/en
Priority to DE3852252T priority patent/DE3852252T2/en
Publication of JPS6471899A publication Critical patent/JPS6471899A/en
Priority to US07/593,586 priority patent/US5084584A/en
Priority to US07/742,155 priority patent/US5169966A/en
Pending legal-status Critical Current

Links

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  • Steroid Compounds (AREA)

Abstract

NEW MATERIAL:A 20-acyloxy-17(20)-methylene-21-al-steroid expressed by formula I (R represents lower alkyl; wavy line indicates that steric configuration of acyloxy and formyl bonded to 20th carbon atom. may be either E type or Z type; dotted line represents single bond or double bond). EXAMPLE:20-Acetoxy-3-oxo-pregna-4,17(20)-dien-21-al. USE:A steroid intermediate useful for producing adrenocortical steroids such as hydrocortisone. PREPARATION:First, 17-position of a 17-ketosteroid expressed by formula II is ethynylated by a conventional method and the 17beta-hydroxyl group of the formed 17alpha-ethynyl-17beta-hydroxysteroid is acylated to afford 17alpha-ethynyl-17beta- acyloxysteroid expressed by formula III. Then this compound is oxidized in a solvent such as DMF by using a catalyst of platinum group metal compound such as palladium chloride.
JP22805587A 1987-09-11 1987-09-11 Steroid compound Pending JPS6471899A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP22805587A JPS6471899A (en) 1987-09-11 1987-09-11 Steroid compound
EP88114770A EP0306969B1 (en) 1987-09-11 1988-09-09 A process for producing an alpha-acyloxy-alpha beta-unsaturated carbonyl compound and a 20-acyl-oxy-17(20)-methylen-21-al-steroid compound
DE3852252T DE3852252T2 (en) 1987-09-11 1988-09-09 A process for producing an alpha-acyloxy-alpha-beta-unsaturated compound and a 20-acyloxy-17 (20) -methylene-21-al-steroid derivative.
US07/593,586 US5084584A (en) 1987-09-11 1990-10-09 Process for producing an α-acyloxy-α,β-unsaturated carbonyl compound and a 20-acyloxy-17(20)-methylen-21-al-steroid compound
US07/742,155 US5169966A (en) 1987-09-11 1991-08-01 Process for producing an α-acyloxy-α, β-unsaturated carbonyl compound and a 20-acyloxy-17(20)-methylen-21-al-steroid compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22805587A JPS6471899A (en) 1987-09-11 1987-09-11 Steroid compound

Publications (1)

Publication Number Publication Date
JPS6471899A true JPS6471899A (en) 1989-03-16

Family

ID=16870490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP22805587A Pending JPS6471899A (en) 1987-09-11 1987-09-11 Steroid compound

Country Status (1)

Country Link
JP (1) JPS6471899A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501115A (en) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α-Hydroxy steroid dehydration method
JP2001236025A (en) * 1999-12-15 2001-08-31 Semiconductor Energy Lab Co Ltd Light emitting device
US7468580B2 (en) 2001-01-31 2008-12-23 Seiko Epson Corporation Display device

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501115A (en) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α-Hydroxy steroid dehydration method
JP2001236025A (en) * 1999-12-15 2001-08-31 Semiconductor Energy Lab Co Ltd Light emitting device
US9843015B2 (en) 1999-12-15 2017-12-12 Semiconductor Energy Laboratory Co., Ltd. Light-emitting device
US7468580B2 (en) 2001-01-31 2008-12-23 Seiko Epson Corporation Display device
US8139005B2 (en) 2001-01-31 2012-03-20 Seiko Epson Corporation Display device

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