JPS6471899A - Steroid compound - Google Patents
Steroid compoundInfo
- Publication number
- JPS6471899A JPS6471899A JP22805587A JP22805587A JPS6471899A JP S6471899 A JPS6471899 A JP S6471899A JP 22805587 A JP22805587 A JP 22805587A JP 22805587 A JP22805587 A JP 22805587A JP S6471899 A JPS6471899 A JP S6471899A
- Authority
- JP
- Japan
- Prior art keywords
- 17beta
- expressed
- formula
- 17alpha
- ethynyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
NEW MATERIAL:A 20-acyloxy-17(20)-methylene-21-al-steroid expressed by formula I (R represents lower alkyl; wavy line indicates that steric configuration of acyloxy and formyl bonded to 20th carbon atom. may be either E type or Z type; dotted line represents single bond or double bond). EXAMPLE:20-Acetoxy-3-oxo-pregna-4,17(20)-dien-21-al. USE:A steroid intermediate useful for producing adrenocortical steroids such as hydrocortisone. PREPARATION:First, 17-position of a 17-ketosteroid expressed by formula II is ethynylated by a conventional method and the 17beta-hydroxyl group of the formed 17alpha-ethynyl-17beta-hydroxysteroid is acylated to afford 17alpha-ethynyl-17beta- acyloxysteroid expressed by formula III. Then this compound is oxidized in a solvent such as DMF by using a catalyst of platinum group metal compound such as palladium chloride.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22805587A JPS6471899A (en) | 1987-09-11 | 1987-09-11 | Steroid compound |
EP88114770A EP0306969B1 (en) | 1987-09-11 | 1988-09-09 | A process for producing an alpha-acyloxy-alpha beta-unsaturated carbonyl compound and a 20-acyl-oxy-17(20)-methylen-21-al-steroid compound |
DE3852252T DE3852252T2 (en) | 1987-09-11 | 1988-09-09 | A process for producing an alpha-acyloxy-alpha-beta-unsaturated compound and a 20-acyloxy-17 (20) -methylene-21-al-steroid derivative. |
US07/593,586 US5084584A (en) | 1987-09-11 | 1990-10-09 | Process for producing an α-acyloxy-α,β-unsaturated carbonyl compound and a 20-acyloxy-17(20)-methylen-21-al-steroid compound |
US07/742,155 US5169966A (en) | 1987-09-11 | 1991-08-01 | Process for producing an α-acyloxy-α, β-unsaturated carbonyl compound and a 20-acyloxy-17(20)-methylen-21-al-steroid compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22805587A JPS6471899A (en) | 1987-09-11 | 1987-09-11 | Steroid compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6471899A true JPS6471899A (en) | 1989-03-16 |
Family
ID=16870490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP22805587A Pending JPS6471899A (en) | 1987-09-11 | 1987-09-11 | Steroid compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6471899A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05501115A (en) * | 1990-03-27 | 1993-03-04 | シェリング・コーポレーション | 9α-Hydroxy steroid dehydration method |
JP2001236025A (en) * | 1999-12-15 | 2001-08-31 | Semiconductor Energy Lab Co Ltd | Light emitting device |
US7468580B2 (en) | 2001-01-31 | 2008-12-23 | Seiko Epson Corporation | Display device |
-
1987
- 1987-09-11 JP JP22805587A patent/JPS6471899A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05501115A (en) * | 1990-03-27 | 1993-03-04 | シェリング・コーポレーション | 9α-Hydroxy steroid dehydration method |
JP2001236025A (en) * | 1999-12-15 | 2001-08-31 | Semiconductor Energy Lab Co Ltd | Light emitting device |
US9843015B2 (en) | 1999-12-15 | 2017-12-12 | Semiconductor Energy Laboratory Co., Ltd. | Light-emitting device |
US7468580B2 (en) | 2001-01-31 | 2008-12-23 | Seiko Epson Corporation | Display device |
US8139005B2 (en) | 2001-01-31 | 2012-03-20 | Seiko Epson Corporation | Display device |
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