JPS63318955A - Preparation of balloon for endoscope - Google Patents

Abstract

PURPOSE:To obtain a transparent membrane main body having high strength, by compounding a small amount of a powdery vulcanizer and a powdery vulcanization promoting aid with natural rubber latex to suppress powdery additives as low as possible and adding a liquid vulcanization promoter and a liquid aging inhibitor to said latex to prepare a compounded solution and immersing mold in said solution to perform vulcanization and drying. CONSTITUTION:A compounded solution is prepared by adding 0.7-1.5pts.wt. of a powder vulcanizer, 0.2-0.5pts.wt. of a powdery vulcanization promoting aid, 0.5-1.0pts. wt. of a liquid vulcanization promoter and 0.5-1.0pts.wt. of a liquid aging inhibitor to 100pts.wt. of the rubber component of natural rubber latex. A mold is immersed in a coagulant and subsequently immersed in the compounded solution for about 30-60sec and slowly drawn up to adhere the natural rubber to the mold in a thickness of about 0.15-0.25mm and the rubber is dried at 80-90 deg.C for about 10min under heating and, after mouth binding, further vulcanized at 80-90 deg.C for about 20min under heating to form a membrane which is, in turn, demolded using a release powder. After the demolded membrane main body A is washed, said membrane main body is treated with a silicone emulsion to develop a transparent feeling and cut into a predetermined length at a mouth end part and an inflatable part 2 is provided to the tip of a fixing cylindrical part as the same body.

Description

[Detailed description of the invention] <Industrial application field> The present invention allows observation and diagnosis of inside blood vessels and luminal organs.

The present invention relates to a method of manufacturing a balloon used in an endoscope for treatment, particularly a balloon suitable for laser beam therapy.

<Conventional technology> Previously, there was no balloon of this kind.

There are vascular tube catheters and arteriovenous indwelling catheters that are inserted into blood vessels and inflated by injecting physiological saline to stop the flow of blood. It wasn't transparent, but laser beams couldn't pass through it or see through it. Furthermore, in the case of transparent rubber products (for example, nipples), powdered vulcanizing agents and vulcanization accelerators have been used, which tends to reduce the strength. Therefore, in order to maintain the strength, it is common practice to increase the thickness, which prevents expansion.

<Problems to be Solved by the Invention> The present invention provides an endoscopic balloon that is transparent, thin, and strong even when expanded, and can transmit laser beams.

<Means for Solving the Problems> The present invention was made in view of the above circumstances, and consists of blending a small amount of powdered vulcanizing agent and powdered vulcanization accelerator into natural rubber latex to suppress the amount of powdered additives as much as possible. , the mold is immersed in a mixed solution containing a liquid vulcanization accelerator and a liquid anti-aging agent.

<Example> To explain an example of the implementation of the present invention, the blended solution contains 0 parts by weight of powder vulcanizing agent for 100 parts by weight of the rubber content of natural rubber latex.
．． 7 to 1.5 parts by weight, preferably 61 parts by weight, 0.8 to 1.2 parts by weight, 0.2 to 0.5 ffl powder vulcanization accelerator, preferably 0.3 to 0.4 parts by weight, and liquid vulcanization. Sulfur accelerator 0.5~
It is made by adding 1.0 parts by weight and 0.5 to 1.0 parts by weight of a liquid anti-aging agent, and its compounding method is to add dispersed vulcanizing agents and vulcanization accelerators to natural rubber latex, After mixing and stirring, vulcanization accelerator and anti-aging agent were added, and 10
After being left in a constant temperature bath at ~15°C for 12 to 24 hours, it is further left in a constant temperature bath at 25 to 35°C for 24 to 48 hours to ripen.

The mold is a so-called immersion manufacturing mold for obtaining a main body with a predetermined size and shape, and after immersing this mold in a coagulant and then immersing it in the mixed solution for about 30 to 60 seconds,
Slowly pull up natural rubber and apply 0.15 to 0.25 degrees of natural rubber, heat and dry at 80 to 90 degrees Celsius for about 10 minutes, wrap it around once, and then heat and vulcanize it at 80 to 90 degrees Celsius for about 20 minutes. The mold is formed into a thin film, removed from the mold using release powder, etc., and the mold is washed, dried, and immersed in the original coagulant again, and this process is repeated.

The demolded a-film body is washed, treated with silicone emulsion to give it a transparent feel, dried at 80° C. for about 60 minutes, and cut at the mouth to a predetermined length. This transparent thin film main body has a fixed cylindrical part and an extensible and expandable part disposed in the same body, and the fixed part has an open end at one end and has an inner diameter of 0.90 to 17.00 mm. It has a roughly cylindrical shape, and by looking through the inflatable part and injecting physiological saline through a channel or air supply port formed in the endoscope, the transparent inflatable part can be adjusted to a predetermined size. It is a spherical body, a bulging body, or a cylindrical body that expands. This llilli portion may be formed to have a larger diameter than the fixed cylindrical portion, a smaller diameter, or the same diameter as the fixed cylindrical portion, or a small diameter constriction or a reinforcing convex portion between the expansion portion and the fixed cylindrical portion. It is also possible to provide the strip rings in one piece. Its inner diameter is also 0.80~35.0a
An appropriate size is selected depending on the degree of AT and the location to be diagnosed and treated, and in any case, it expands when saline is injected, making the thin film even thinner, improving fluoroscopy and allowing laser beams to pass through.

Specific implementation mode Natural rubber latex (poly-164-isoprene) Rubber content 100 parts by weight Powder vulcanizing agent (colloidal sulfur) 1.2 parts by weight Powder vulcanization accelerator (allium oxide) 0.35 parts by weight Part vulcanization accelerator (dithiocarbamate type) 0.7 weight part Anti-aging agent (
A blended solution consisting of 1.0 parts by weight of paraffin emulsion is used.

The mold was slowly immersed in a coagulant solution containing 10% calcium nitrate/methanol at room temperature, immediately pulled up slowly, and then slowly immersed in the above-mentioned mixed solution for 3 hours at room temperature.
After 0 to 60 seconds, slowly lift it up and let the natural rubber adhere to it.8
After drying at 0°C for 10 minutes and wrapping, heat and vulcanize at 90°C for 20 minutes to form a fixed cylinder with a film thickness of 0.16 m and an inner diameter of 1.94 M, and a film thickness of 0.22 m at the tip. M, inner diameter is 1.
The film thickness is 0.16 mm through the constriction of 54111i,
The spherical parts with an inner diameter of 1.81 mta were made into a thin film-like product with a uniform body and a film thickness of 0.19 mm on the top surface of the expanded part, and the thin film-like product was demolded using release powder. After washing with 0.5% ammonia water for about 16 hours, it was soaked evenly in a 10% silicone emulsion at room temperature and dried at 80°C for 60 minutes to obtain a transparent thin film body with excellent transparency.

The transparent thin film body <A) dip-molded as described above is not limited to the above-mentioned dimensions and wall thickness, but as shown in Figs. 2) are formed into the same body, and if necessary, a constriction part (
3) or any form and size provided with a convex ring (4),
This main body (A) is fixed to the distal end (b) of an endoscope (B) as shown in FIG. 5, and is attached so that the inflatable part protrudes. The tip (b) of the family celebration 1 (B) is the 6th
As shown in the figure, two light guides (b-1) (b-1
), objective lens (b-2), channel for inserting treatment instruments, treatment instruments, forceps, etc. (b-3), air and water supply port (b-
4) etc., and is of a well-known structure that can be freely moved up, down, left and right. After attaching the above-mentioned main body (Δ) to the distal end (b) of such an endoscope (B), it is possible to inspect the inside of blood vessels and luminal organs (esophagus, esophagus, etc.).
Stomach, bifatty intestine, large intestine.

(pharynx, biliary tract, abdominal cavity, bladder, uterine shin, etc.) and inject physiological saline through the endoscopy & Q (B) channel (b-3) or the air and water supply port (b-4). Inject it, expand the inflatable part (2) to its fullest extent, observe or diagnose the affected area such as a bleeding site or lesion, and treat it by inserting an optical fiber (bs) into the channel (b-3) and irradiating it with a laser beam. It is.

Because it is used in this way, if the main body (A), especially the expansion part (2) when expanded, is opaque, there is a risk of the affected area being unclear and being overlooked.Furthermore, since the laser beam is irradiated, if the body (A) is opaque, there is a risk of overlooking the affected area. Not only does the therapeutic effect not improve due to poor permeability, but also energy is absorbed into the main body, reducing the durability of the main body, so the main body must have both skin properties and transparency. Must be.

Effectiveness> The present invention uses 0.1 to 1.5 parts by weight of a powder vulcanizing agent, 0.2 to 0.5 parts by weight of a powder vulcanization accelerator, and a liquid Vulcanization accelerator 0.5-1.
The mold is immersed in a mixed solution containing 0 parts by weight ω and 0.5 to 1.0 parts by weight Ld of a liquid anti-aging agent and vulcanized and dried, so it is transparent and has great strength. A thin film body is obtained.

In addition, by attaching this transparent thin film body to the tip of the endoscope, blood, secretions, food, etc. will not adhere to the light guide, objective lens, or optical fiber, and the affected area will not be difficult to see, making diagnosis and treatment easier. In addition, the inflatable part can be easily inflated by injecting physiological saline, thereby creating a predetermined space, widening the field of view, and making it possible to observe and diagnose or treat the affected area more reliably. For example, we can diagnose the focus of thrombotic disease, treat the focus by irradiating the focus with a laser beam, or apply pressure to the focus of esophageal varices or the focus of the stomach or diabetic intestine to control bleeding and stop the bleeding. It can be treated by tightening or widening the narrowed area. YAG laser transmits optical fibers to affected areas in other organs as well.

It can also be treated by irradiating laser beams such as argon laser or argon dye laser to stop bleeding or cauterize the lesion, which is useful in providing new treatment methods.

Moreover, when used inside a blood vessel, the inflatable part can be inflated and brought into close contact with the inner surface of the blood vessel to stop the blood flow. There is no need to make an incision, and there is no need for a member such as a catheter, making treatment easier.

[Brief explanation of drawings]

The drawings show a transparent thin film body manufactured by the manufacturing method of the present invention, in which FIG. 1 is a longitudinal sectional front view, FIGS. 2 to 4 are longitudinal sectional front views of other embodiments, and FIG. 5 is an interior view. Fig. 6 is an enlarged view of the distal end of the endoscope, and Fig. 7 is an enlarged view of the endoscope in use when inserted into a blood vessel. (A) is the main body, (1) is the tube. The shaped fixation part (2) is the i-bulge part.

Claims (1)

[Claims] 0.7 to 1.5 parts by weight of powder vulcanizing agent and 0.2 parts by weight of powder vulcanization accelerator for 100 parts by weight of rubber content of natural rubber latex.
~0.5 parts by weight, 0.5 to 1.0 parts by weight of a liquid vulcanization accelerator, and 0.5 to 1.0 parts by weight of a liquid anti-aging agent are added to form a compounded solution, and a mold is added to this solution. A method for producing an endoscopic balloon consisting of a transparent thin film body, which is dipped in natural rubber to adhere natural rubber, vulcanized and dried, and then demolded to form an inflatable part at the end of a cylindrical fixing part.