JPS6313224Y2 - - Google Patents

Description

[Detailed description of the invention] Conventional bulges have been prepared by adding a base material such as kaolin or bentonite to the surface of a woven or non-woven fabric, a wetting agent such as sorbitol, glycerin, propylene glycol, or an alkaline earth metal salt, methyl salicylate, peppermint oil, or the like.
A poultice layer containing drugs such as menthol, thymol, camphor, and other necessary materials is provided.
The effects of these poultices are thought to be exerted by the analgesic and anti-inflammatory effects of the combined drugs and the cooling effect of water. For this reason, various efforts have been made to improve the drug release properties and water-based cooling properties of poultices, as well as to provide adhesiveness to the poultices.However, in systems containing water such as conventional poultices,
It is difficult to adjust the adhesion and cohesive force of the poultice layer (the cohesive force that prevents the poultice from remaining on the skin when peeled off), and it is difficult to obtain a well-balanced product. In addition, salicylic acid ester drugs are unstable in water. However, there were disadvantages such as the problem of deterioration over time.

This product is formed into a composite material that has a drug-containing adhesive layer that has adhesion to the skin and analgesic and anti-inflammatory effects, and a hydrous gel that has a cooling effect. The aim is to provide extremely good quality and quality.

To explain an example below, a drug-containing adhesive layer 2 is provided on the releasable surface of a sheet material 1 that is releasable to an adhesive, and a protein-based hydrogel such as gelatin or casein is provided on the upper surface of the adhesive layer. A layer 4 is provided to form a poultice.

The above hydrogelated products include gelatin, casein,
These gels may contain kaolin, bentonite, calcium carbonate, other inorganic substance powders, propylene glycol, sorbitol, glycerin, magnesium chloride and other hygroscopic substances, thymol, etc., as necessary. Appropriate amounts of other preservatives and other various substances used in conventional poultice layers can be added.
The raw materials used to form the above-mentioned water-containing gelatinized substance include 12 parts of gelatin (the same applies below weight), 55 parts of glycerin, 18 parts of calcium carbonate, 5 parts of titanium oxide,
2.5 parts of magnesium chloride, 0.5 parts of Sunwet 1M300 (Sanyo Kasei KK brand name), 4 parts of sodium polyacrylate, 2 parts of liquid paraffin, 1 part of Twin 80 (Kao Atlas KK brand name), 0.1 part of glutaraldehyde.
1 part, 0.5 parts of thymol, and 99.4 parts of purified water.
g/m ² on the pressure-sensitive adhesive layer, cooled, solidified, and formed into a hydrogel, and left for another week to form a stabilized hydrogel.

The drugs include methyl salicylate, glycol salicylate, menthol, camphor, borneol, nonylic acid vanillylamide, pepper oil, capsicum extract, belladonna extract, rotisserie extract, diphenhydramine, and other substances that have anti-inflammatory, analgesic, and stimulant effects. There are various types of adhesives that contain chemicals, such as rubber-based, acrylic-based, vinyl ether-based, and silicone-based adhesives, which can be used as appropriate depending on the purpose. In addition to paper treated with silicone, higher fatty acids, etc., the releasable sheet material 1 may also include polyethylene laminated paper treated with the above-mentioned release agent, if necessary.
polyethylene, polypropylene, polyester,
Aluminum foil laminated polyethylene and other plastic films are available.

The poultice formed as described above is used by cutting it into a required size, peeling off the releasable sheet material, and pasting it on the affected area via the drug-containing adhesive layer.
This poultice can be used as it is or cut into pieces of the required size, e.g. 14 x 10 cm square, and the upper surface of the gelled substance may or may not be covered with polyethylene or other film, and the appropriate number of films, e.g.
The sheets are sealed in bags made of aluminum foil laminated film and supplied to the market.

Since the present invention is constructed as described above, it can be firmly attached to the affected skin surface with an adhesive force comparable to that of adhesive tape (adhesive force to Bakelite of about 300 g/30 mm), and the drug can be placed close to the affected area and its effect can be maintained. In addition, since the drug does not disperse in water, no hydrolysis occurs, and salicylic acid ester drugs can also be used, and the cooling effect due to the hydrous gel layer Together with this, it has an extremely large therapeutic effect.

[Brief explanation of the drawing]

The drawings show an example of the present invention, and Figure 1 is a slope view;
Figure 2 is a sectional view. 1 is a removable sheet material, 2 is a drug-containing adhesive layer,
4 is a hydrous gelled material layer.

Claims (1)

[Scope of utility model registration request] A poultice with a hydrogelled protein layer such as gelatin or casein formed on a drug-containing adhesive layer.