JPS63102747A - Bio-signal detector - Google Patents

Abstract

(57) [Abstract] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION [Object of the Invention] (Industrial Application Field) The present invention relates to a biological signal detection device that detects signals from a biological body for the purpose of diagnosis.

(Prior technology) Sudden intracranial hemorrhage (stroke) such as subarachnoid hemorrhage is the leading cause of death in Japanese people, but these are caused by hypertensive cerebral hemorrhage and intracranial vascular abnormalities. It is broadly classified into bleeding based on Blood vessel abnormalities include arteriovenous malformations in which arterial blood flows directly into veins without passing through capillaries, aneurysms in which a portion of the artery wall abnormally expands and protrudes, and arterial stenosis, but the most common are The number of deaths due to subarachnoid hemorrhage due to rupture of a cerebral aneurysm is thought to be approximately 5 per 100,000 people each year. Furthermore, while hypertensive cerebral hemorrhage is concentrated in the elderly, the frequency of subarachnoid hemorrhage is 3.
Another characteristic is that it shows almost uniformly high values from 5 to 65 years of age.

Detecting such vascular abnormalities before they lead to bleeding is extremely important from a preventive medical standpoint, but the current method of detecting vascular abnormalities in the brain is angiography, which is performed by injecting a contrast medium into the intracerebral arteries. is mainly used. This test is often painful and dangerous, so less invasive testing methods are needed. One of them is the method using CT,
Diagnosis is not easy unless the lesion in the affected area is very large. Attempts have also been made to diagnose vascular abnormalities using ultrasound; however, in the case of intracranial vascular abnormalities, the ultrasound is significantly attenuated in the cranium, so the cranium is removed during surgery. Alternatively, it is limited to obtaining some diagnostic information about the carotid artery from the neck.

(Problems to be Solved by the Invention) As mentioned above, there was a problem in that it was difficult to non-invasively detect blood vessel abnormalities with conventional devices.

The present invention uses a highly sensitive detection means placed on the scalp to detect sounds caused by disturbances in blood flow that occur in abnormal areas of the skull, and detects only one type: presence or absence of a lesion.

It is an object of the present invention to provide a biological signal detection device necessary for non-invasive diagnosis of grade 2 sites and the like.

[Means for solving problems and their effects] The present invention includes a special accelerometer that detects biological signals with ultrahigh sensitivity, a holding means for holding this accelerometer, and a head fixation stand. A spherical anti-photograph material is provided on the head of the holding means, and by supporting this, (the acoustic external noise of the shindo hat is reduced and the head It is characterized by easy setting even at any measurement site.

(Example) The present invention will be specifically explained below using Examples.

FIG. 1 shows an embodiment of the configuration of a detection section used in the device of the present invention. This is constituted by a special accelerometer 1, a holding device having a main body holding part 2 and a spherical top part 3 for holding the special accelerometer 1. The main body holding part 2 has a cylindrical part 2A, an upper holding plate 2B, a bottom holding plate 2C, and an intermediate rib 2D. A compression spring (pressing spring) 4 is provided between the upper end of the accelerometer 1 and the upper holding plate 2B.
1 is pressed downward with a predetermined pressure. This spring 4 is filled with silicone grease to prevent resonance with the holding portion. 2E is a fixing ring for ensuring the fixation of the holding part main body 2. Each part of the holder main body has an anti-vibration structure using silicone rubber and anti-vibration rubber material.

The spherical top part 3 is made of anti-vibration rubber, has a spherical shape as a whole, has a hole 3A for pulling out the cord 5 in the center, has a cylindrical stopper 3B at the top, and a connecting part 3C at the bottom. It is screwed to the holding part main body via.

FIGS. 2(a) and 2(b) are a front view and a side view showing an embodiment of the apparatus of the present invention to which the detection section is attached.

The support device 10 is composed of an inverted U-shaped support frame 11 having a size that allows insertion of the head of the living body P, and a support la structure 12 attached to this frame. The support mechanism section 12 includes a stand leg fixing base 13 and a support lever 14 rotatably supported on the fixing base.
It consists of a leaf spring 15 that restricts the upward movement of the
A ring-shaped portion 14A capable of holding the spherical head 3 of the detection portion is provided at the tip of the support lever 14. This clamping pressure is such that the position of the spherical head 3 can be changed by applying an external force.

The inverted U-shaped frame 11 is slidably attached at its bottom to the side surface of the U-shaped living body head fixing table 16, and is movable in the directions Al and A2 shown in the figure. And fixing screw 17 on the side of the frame.
．． 17, and can be fixed at a desired position by tightening the screw 17. The bottom surface of the head fixing table 16 is attached to a plate 19, and the top surface of the head fixing table is provided with a flexible holding member 18 for holding the living body's head. Note that 20 is an amplifying section including a battery as a power source attached to the plate, and is connected to a cord 5 etc. extending from the special acceleration h4.

Here, the figure shows an example in which two detection units are installed so that biological signals of two channels can be detected, but one
There may be only one, or three or more. The number of amplification sections may be increased or decreased accordingly. Furthermore, the amplification section may not necessarily be provided nearby, but may be placed separately.

Next, the detection principle of the detection section will be explained.

First, the special acceleration h used in the device will be explained.

This special accelerometer can be used with the following specifications.

(1) Sensitivity Voltage sensitivity 1F3 QmV/G or more (2) Response frequency 5H2 to 5KH2 (3) Resonance frequency 10KHz or more (4) Operating temperature range O
'C ~ 80'C (5) Weight: 20gr or less (6) Case material: Titanium (7) Outer diameter: φ16X35 Such a special accelerometer 1 is held in a vibration-proof manner by a holding device 2 as shown in Fig. 3. However, when a biological signal is detected by pressing it against the scalp Pa of a living body while being pressed by the spring 4, an equivalent circuit as shown in FIG. 4 is established. In FIGS. 3 and 4, md and M are the masses of the accelerometer 1 and the holding device 2,
Sd is the stiffness of spring 4,
rd is the uniform resistance of the damper. mh, 5h, and rh represent the mechanical impedance of the head, and represent the constants of the equivalent circuit calculated from the results measured by each pressure, as shown in Table 1 below.

Table 1 Part of the subject Pressing is pressure Effective resistance rh Effective quality fi
mh Stiffness shA Temporal head 0.1
6.91 0.00295 1.05 X1
040.25 9.03 0.00312
4.14X1040.4 10.7 0
．． 00321 5.35 X104B Temporal region
0.1 5.8 0.00271 0.
9 X1040.25 8.62 0.0
0274 1.73 X1040.4 9.9
1 0.002702.67 It is important to take sufficient pressure, and the above table shows that the spring pressure (pressing force) was confirmed through various experiments and analysis using an equivalent circuit. It has been found that this method is preferable since there are no effects such as these.

Next, the operation of the device will be explained.

As shown in FIG. 2, the device is positioned with respect to the biological head P held on the holding member 18 of the head fixing section.

For this positioning, the inverted U-shaped frame 11 of the support device 10 is brought into contact with the side wall surface of the head fixing base 16 and moved back and forth, and the fixing screws 17. Tighten and secure '17. Then, the lever 14, which is rotatably attached to the fixed base 13 on the frame 11, is slightly lifted by hand and placed on the target position of the head P. Adjustment is then carried out by gripping the spherical top 3 portion and applying an external force so that the tip end surface of the detection portion matches the head surface and rotationally moving it relative to the support ring 14A. Thereafter, the amplifying section 20 and the special accelerometer are operated to detect a biological signal from the detecting section.

The overall frequency characteristics of the device used in this way are
As shown in the figure. This is a comprehensive frequency characteristic showing the relationship between frequency and gain, and has a substantially flat characteristic from around 100 Hz to 5 KHz, indicating that blood flow noise can be detected with high sensitivity.

This is because the spring pressure is stably maintained at about 250 gW, and the spherical top 3 made of anti-vibration rubber provides linear insulation between the support device 10 and the holding device to prevent external acoustic noise. This is because the pressure spring is filled with grease to suppress resonance between the accelerometer 1 and the holding device.

[Effects of the Invention] According to the present invention described in detail above, the presence or absence of a lesion is detected by detecting the sound generated by disturbance of blood flow occurring in an abnormal part of a cranial blood vessel, for example, using a highly sensitive detection means placed on the scalp. It is possible to provide a biological signal detection device necessary for non-invasive diagnosis of two types and two locations. Moreover, since the structure does not transmit the imaging of the detection part to the support part or the holding part, it is possible to prevent the effects of resonance and external noise, and since the pressing force is set appropriately, it has the effect of not causing pain to the patient. have

Furthermore, this detection device is effective not only for detecting blood flow noise occurring in abnormal areas of cranial blood vessels, but also for detecting weak sounds from relatively hard body parts (such as the knee joint) that were previously difficult to measure. be.

[Brief explanation of the drawing]

FIG. 1 is a front view including a half cross section showing one embodiment of the configuration of the detection unit used in the device of the present invention, and FIGS. 2(a) and (b) are front views showing one embodiment of the device of the present invention. 3 is a schematic diagram for explaining the detection principle of the detection section, FIG. 4 is an equivalent circuit diagram thereof, and FIG. 5 is a comprehensive frequency characteristic diagram obtained by the device of the present invention. DESCRIPTION OF SYMBOLS 1... Accelerometer, 2... Holding part, 3... Spherical top part, 4... Pressing spring, 10... Support device, 11...
Frame, 12... Support mechanism section, 14... Support lever. Agent Patent Attorney Masayoshi Misawa 4th cause

Claims (2)

[Claims] (1) A device for detecting biological signals using an accelerometer, which includes a holding means that holds the accelerometer and includes a spherical part made of a vibration-proofing material on the top thereof, and the spherical part is rotatable. 1. A biological signal detection device comprising: supporting means for supporting the biological signal. (2) The biological signal detecting device according to claim 1, wherein the holding means includes a pressing spring that presses the accelerometer against the object to be measured.