JPS60129057A - Needle like solid drug administering needle - Google Patents
Needle like solid drug administering needleInfo
- Publication number
- JPS60129057A JPS60129057A JP58236996A JP23699683A JPS60129057A JP S60129057 A JPS60129057 A JP S60129057A JP 58236996 A JP58236996 A JP 58236996A JP 23699683 A JP23699683 A JP 23699683A JP S60129057 A JPS60129057 A JP S60129057A
- Authority
- JP
- Japan
- Prior art keywords
- needle
- administration
- solid drug
- solid preparation
- drug administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】 本発明は、針状固形製剤投与針に関するものである。[Detailed description of the invention] TECHNICAL FIELD The present invention relates to a needle-shaped solid drug administration needle.
さらに詳しくは、注射針内部に内部を自由に滑り動く押
出し棒を有することを特徴とする針状固形製剤投与針に
関するものである。More specifically, the present invention relates to a needle-like solid drug administration needle characterized by having a push rod that freely slides inside the injection needle.
従来固形薬物を体内に埋め込んで治療することは知られ
ていたが、その埋め込み手段は手術を伴い繁雑であった
。Conventionally, it has been known to implant solid drugs into the body for treatment, but the method of implantation was complicated and required surgery.
本発明者らは、この点に着目し、注射埋め込みによる簡
便な投与方法について鋭意検討した結果、針状の固形製
剤を別途開発す乞と共に木゛発明の投与針を発明するに
至った。The present inventors focused on this point, and as a result of intensive study on a simple administration method by injection implantation, they came up with the invention of the administration needle of the tree invention along with the separate development of a needle-shaped solid preparation.
すなわち、注射針内部に内部を自由に滑り動く押山出し
棒を有する投与針を開発することにより、臨床上きわめ
て有用な針状固形製剤の投与針を得、本発明を完成した
ものである。That is, by developing an administration needle that has a protruding rod that freely slides inside the injection needle, we have obtained an administration needle for needle-shaped solid preparations that is extremely useful clinically, thereby completing the present invention.
さらに詳細に説明するならば注射針とは通常注射に用い
られる針であり、押し出し棒とはその径が、注射針の内
径と一致するか、や＼小さいもので、通常０．５〜５簡
の斜状固形製剤を押し出すことができるものである。To explain in more detail, a syringe needle is a needle normally used for injections, and a push rod is one whose diameter matches or is slightly smaller than the inner diameter of the syringe needle, and is usually 0.5 to 5 mm smaller. It is possible to extrude oblique solid preparations.
なお、この針状固形製剤投与剤は通常適当な保持器具（
４）に取りつけて用いるが、ファイバースコープの鉗子
先端につけて用いることも可能である。Note that this needle-shaped solid preparation is usually held with a suitable holding device (
4), but it can also be used by attaching it to the tip of the forceps of a fiberscope.
次に本発明の投与針による針状固形製剤の投与方法を具
体的に説明する。すなわら、あらかしめ、注射針（１）
内部に固形針状製剤（２）を保持させておき（図１）、
注射針（１）を身体投与部に゛ さし込むと同時に押し
出し棒（８）を使−て製剤 （を身体投与部（５）に押
し出し、投与する（図２）。Next, a method for administering a needle-shaped solid preparation using the administration needle of the present invention will be specifically explained. In other words, a summary, a hypodermic needle (1)
A solid needle-like preparation (2) is held inside (Figure 1),
The injection needle (1) is inserted into the body administration site, and at the same time, the push rod (8) is used to push out the preparation into the body administration site (5) for administration (Figure 2).
なお、胃壁等の体内深部に穿刺、投与する時は、ファイ
バースコープの処置具として本投与針を用い、ファイバ
ースコープの手元部操作により、体内深部投与部におい
て穿刺、押し出し棒作動を行ない薬物投与することも可
能である。When puncturing and administering to deep parts of the body such as the stomach wall, use this administration needle as a treatment tool for the fiberscope, and use the fiberscope's hand to operate the puncture and push rod at the deep body administration site to administer the drug. It is also possible.
この場合は本投与針より製剤が落ちないように、投与時
取りはずし可能なカバー（６）を投与針先端にっけてお
くことが好ましい（図８）。In this case, it is preferable to attach a removable cover (6) to the tip of the administration needle to prevent the preparation from falling from the administration needle (FIG. 8).
本投与針で投与される針状固形製剤の形は針状ないし細
棒状のもので通常の注射針内部に保−持され得るもので
あれば釦用なるものでも良い。The needle-shaped solid preparation to be administered with this administration needle may be in the shape of a needle or a thin rod, and may be a button-shaped one as long as it can be held inside an ordinary injection needle.
図１は針状固形製剤を保持した本発明針状固形製剤投与
針の一例を示したものである。
図２は本発明針状固形製剤投与針を用いて、針状固形製
剤を体内に投与した状態の一例を示したものである。
図８は針状固形製剤を保持し、かつそれが落ちないよう
に取りはずし可能なカバーを取りつけた本発明針状固形
製剤投与針の一例を示したものである。
図中の数字は次を意味するFIG. 1 shows an example of the needle-shaped solid preparation administration needle of the present invention holding a needle-shaped solid preparation. FIG. 2 shows an example of a state in which a needle-like solid preparation is administered into the body using the needle-like solid preparation administration needle of the present invention. FIG. 8 shows an example of the needle-shaped solid preparation administration needle of the present invention, which holds a needle-shaped solid preparation and is equipped with a removable cover to prevent the solid preparation from falling. The numbers in the diagram mean the following
Claims (1)
ることを特徴とする針状固形製剤投与針A needle-like solid drug administration needle characterized by having a push-out rod that freely slides inside the injection needle.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58236996A JPS60129057A (en) | 1983-12-14 | 1983-12-14 | Needle like solid drug administering needle |
| EP19840112310 EP0139286B1 (en) | 1983-10-14 | 1984-10-12 | Prolonged sustained-release preparations |
| DE8484112310T DE3484951D1 (en) | 1983-10-14 | 1984-10-12 | EXTENDED PREPARATIONS WITH DELAYED DELIVERY. |
| US06/846,193 US4774091A (en) | 1983-10-14 | 1986-03-31 | Long-term sustained-release preparation |
| US07/187,443 US5021241A (en) | 1983-10-14 | 1988-04-28 | Long-term sustained-release preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58236996A JPS60129057A (en) | 1983-12-14 | 1983-12-14 | Needle like solid drug administering needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS60129057A true JPS60129057A (en) | 1985-07-10 |
Family
ID=17008839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58236996A Pending JPS60129057A (en) | 1983-10-14 | 1983-12-14 | Needle like solid drug administering needle |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60129057A (en) |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05236840A (en) * | 1986-10-06 | 1993-09-17 | Bio Medic Data Syst Inc | Needle assembly for animal mark embedding device |
| JP2016105795A (en) * | 2010-09-13 | 2016-06-16 | エヌディーエム テクノロジーズ リミテッド | Transdermal administration device |
| JP2016193946A (en) * | 2011-06-29 | 2016-11-17 | ラニ セラピューティクス， エルエルシー | Therapeutic agent preparations for delivery into lumen of intestinal tract using swallowable drug delivery device |
| US10004783B2 (en) | 2010-12-23 | 2018-06-26 | Rani Therapeutics, Llc | Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10029080B2 (en) | 2010-12-23 | 2018-07-24 | Rani Therapeutics, Llc | Method for delivering exenatide into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10039908B2 (en) | 2009-12-24 | 2018-08-07 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| JP2019055197A (en) * | 2011-06-29 | 2019-04-11 | ラニ セラピューティクス， エルエルシー | Devices, systems and methods for oral delivery of therapeutic compounds |
| US10300010B2 (en) | 2010-12-23 | 2019-05-28 | Rani Therapeutics, Llc | Methods for delivering entanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10307579B2 (en) | 2010-12-23 | 2019-06-04 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10314892B2 (en) | 2010-12-23 | 2019-06-11 | Rani Therapeutics, Llc | Method of delivering a somatostatin compound into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10322167B2 (en) | 2010-12-23 | 2019-06-18 | Rani Therapeutics, Llc | Method of delivering gonadotropin releasing hormone or an analogue thereof into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10335463B2 (en) | 2010-12-23 | 2019-07-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10350163B2 (en) | 2010-12-23 | 2019-07-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10478396B2 (en) | 2010-12-23 | 2019-11-19 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10487145B2 (en) | 2010-12-23 | 2019-11-26 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10548850B2 (en) | 2010-12-23 | 2020-02-04 | Rani Therapeutics, Llc | Therapeutic composition comprising insulin prepared for delivery into an intestinal tract |
| US10632251B2 (en) | 2010-12-23 | 2020-04-28 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10752681B2 (en) | 2010-12-23 | 2020-08-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| CN112004523A (en) * | 2018-03-13 | 2020-11-27 | 沃泰克斯药物股份有限公司 | Implant devices, systems, and methods |
| US11439817B2 (en) | 2009-08-03 | 2022-09-13 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
-
1983
- 1983-12-14 JP JP58236996A patent/JPS60129057A/en active Pending
Cited By (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05236840A (en) * | 1986-10-06 | 1993-09-17 | Bio Medic Data Syst Inc | Needle assembly for animal mark embedding device |
| US11439817B2 (en) | 2009-08-03 | 2022-09-13 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
| US11872396B2 (en) | 2009-08-03 | 2024-01-16 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
| US10252039B2 (en) | 2009-12-24 | 2019-04-09 | Rani Therapeutics, Llc | Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US11376405B2 (en) | 2009-12-24 | 2022-07-05 | Rani Therapeutics, Llc | Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10039908B2 (en) | 2009-12-24 | 2018-08-07 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| US10179228B2 (en) | 2009-12-24 | 2019-01-15 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US11338118B2 (en) | 2009-12-24 | 2022-05-24 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US10493253B2 (en) | 2009-12-24 | 2019-12-03 | Rani Therapeutics, Llc | Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US11253686B2 (en) | 2009-12-24 | 2022-02-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US10987499B2 (en) | 2009-12-24 | 2021-04-27 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| US10596359B2 (en) | 2009-12-24 | 2020-03-24 | Rani Therapeutics, Llc | Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9770578B2 (en) | 2010-09-13 | 2017-09-26 | Ndm Technologies Limited | Devices for transdermal drug delivery |
| JP2016105795A (en) * | 2010-09-13 | 2016-06-16 | エヌディーエム テクノロジーズ リミテッド | Transdermal administration device |
| US10314892B2 (en) | 2010-12-23 | 2019-06-11 | Rani Therapeutics, Llc | Method of delivering a somatostatin compound into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10980749B2 (en) | 2010-12-23 | 2021-04-20 | Rani Therapeutics, Llc | Therapeutic preparation comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10335463B2 (en) | 2010-12-23 | 2019-07-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10350163B2 (en) | 2010-12-23 | 2019-07-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10478396B2 (en) | 2010-12-23 | 2019-11-19 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10487145B2 (en) | 2010-12-23 | 2019-11-26 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10314891B2 (en) | 2010-12-23 | 2019-06-11 | Rani Therapeutics, Llc | Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10548850B2 (en) | 2010-12-23 | 2020-02-04 | Rani Therapeutics, Llc | Therapeutic composition comprising insulin prepared for delivery into an intestinal tract |
| US10307579B2 (en) | 2010-12-23 | 2019-06-04 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10632251B2 (en) | 2010-12-23 | 2020-04-28 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10752681B2 (en) | 2010-12-23 | 2020-08-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US11844867B2 (en) | 2010-12-23 | 2023-12-19 | Rani Therapeutics, Llc | Method of delivering insulin into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10864254B2 (en) | 2010-12-23 | 2020-12-15 | Rani Therapeutics, Llc | Method of delivering gonadotropin releasing hormone or an analogue thereof into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10874840B2 (en) | 2010-12-23 | 2020-12-29 | Rani Therapeutics, Llc | Preparation comprising exanatide for delivery into a lumen of the intestinal tract |
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| US10967050B2 (en) | 2010-12-23 | 2021-04-06 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10322167B2 (en) | 2010-12-23 | 2019-06-18 | Rani Therapeutics, Llc | Method of delivering gonadotropin releasing hormone or an analogue thereof into a lumen of the intestinal tract using a swallowable drug delivery device |
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| US10029080B2 (en) | 2010-12-23 | 2018-07-24 | Rani Therapeutics, Llc | Method for delivering exenatide into a lumen of the intestinal tract using a swallowable drug delivery device |
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| JP2019043967A (en) * | 2011-06-29 | 2019-03-22 | ラニ セラピューティクス， エルエルシー | Therapeutic agent preparations for delivery into lumen of intestinal tract using swallowable drug delivery device |
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| JP2016193946A (en) * | 2011-06-29 | 2016-11-17 | ラニ セラピューティクス， エルエルシー | Therapeutic agent preparations for delivery into lumen of intestinal tract using swallowable drug delivery device |
| JP2021517832A (en) * | 2018-03-13 | 2021-07-29 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | Implantable devices, systems, and methods |
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