JPS591409A - Dentifrice composition - Google Patents

Abstract

PURPOSE:To provide a dentifrice composition containing pyrogenetic silica, having suppressed astringency of the pyrogenetic silica and improved feeling to the palate, by adding a specific amount of a phosphate selected from orthophosphate, polyphosphate and metaphosphate to a dentifrice composition containing pyrogenetic silica. CONSTITUTION:A dentifrice composition containing pyrogenetic silica, e.g. toothpaste, moistened dentifrice, powdery dentifrice, etc. is added with 0.01-1wt% of one or more phosphoric acid salts selected from orthophosphates, polyphosphates and metaphosphates, especially from potassium pyrophosphate, sodium pyrophosphate, trisodium pyrophosphate, disodium pyrophosphate, sodium polyphosphate, sodium tripolyphosphate, potassium tripolyphosphate, potassium metaphosphate, sodium trimetaphosphate, sodium hexametaphosphate, and sodium heptametaphosphate. The astringent taste of the pyrogenetic silica can be suppressed effectively, and a dentifrice composition having excellent feeling can be obtained.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a dentifrice composition containing pyrogenic silica that has suppressed astringency and has an excellent feeling of use.

BACKGROUND ART Conventionally, it has been known to incorporate bulk silica into dentifrice compositions such as toothpastes in order to improve shape retention and the like. In addition, in transparent toothpastes that use silica-based abrasives, hydrated amorphous silica is the main abrasive, but hydrated amorphous silica has high hardness, and the more it is used, the more abrasive it becomes. Therefore, the amount of hydrated amorphous silica was reduced,
In order to cover this problem, it has been proposed to incorporate bulk silica as an extender. However, since Taisei Silica is manufactured by thermally decomposing nitric chloride, chlorine inevitably remains, and if Taisei Silica is added to toothpaste, it will have a strong astringent taste derived from this chlorine. There were some problems with the usability, such as the need to use a strong or special flavor to suppress the flavor.

The present inventors conducted various studies to improve the above-mentioned situation, and as a result, the present inventors found that, for toothpaste compositions containing bulk silica, one of orthophosphates, polyphosphates, and metaphosphates.
The species or two or more species may be added in an amount of 0.01 to 1% (wt%) of the entire composition.
, hereinafter the same)), the astringency derived from macrogenic silica can be effectively suppressed and the usability of the dentifrice composition can be improved, and the present invention has been completed based on this finding.

The present invention will be explained in detail below.

The dentifrice composition of the present invention is a dentifrice composition such as a toothpaste, a moisturized toothpaste, or a powdered toothpaste containing macrogenic silica.
It is made by blending one or more seeds, thereby suppressing the astringent taste derived from bulk silica and improving the feeling of use.

In this case, the orthophosphates include sodium dihydrogen phosphate anhydrous salt, monohydrate and dihydrate salt, dihydrogen phosphate
trisodium phosphate anhydrous, dihydrate, heptahydrate and dodecahydrate, trisodium phosphate hexahydrate and octahydrate, potassium dihydrogen phosphate, dipotassium hydrogen phosphate anhydrous, dihydrate and 6 Water salt, tripotassium phosphate octahydrate, heptahydrate, nonahydrate, etc.
Examples of polyphosphates include potassium birophosphate, sodium birophosphate, trisodium birophosphate, disodium birophosphate, sodium polyphosphate, sodium tripolyphosphate, potassium F-ribolyphosphate, etc.; examples of metaphosphates include potassium metaphosphate, trimetaline, etc. Although sodium acid, sodium hexametaphosphate, sodium heptametaphosphate, etc. can be suitably used, polyphosphate R salt and metaphosphate are particularly preferable from the viewpoint of the astringency suppressing effect.

The dentifrice composition of the present invention contains one or more of the above-mentioned phosphates, but it is necessary that the content of the phosphate is 0.01 to 1% of the total composition; If it is less than .oi%, the astringency cannot be sufficiently suppressed, and if it is more than 1%, the flavor of the toothpaste will change, which is not preferable.

In the present invention, the amorphous macrogenic silica is D
egussa's Aerosil N US fd 0abo
Cab-0-Si1 manufactured by Company T can be used. These bulk silicas can be used singly or in combination of two or more, and the blending amount is not particularly limited, but is usually 0.1 to 6%, preferably 0.5 to 4%.

As other components of the present invention, appropriate components can be used depending on the type of 'tkI polishing composition. For example, in the case of toothpaste, dibasic calcium phosphate dihydrate.

hydrates and anhydrides, monocalcium phosphate, octadic calcium phosphate, calcium carbonate, calcium billuphosphate, aluminum hydroxide, alumina, silicic anhydride, silica gel, aluminum silicate, insoluble sodium metaphosphate,
8th phosphoric acid! Abrasives such as gnesium, magnesium carbonate, calcium sulfate, polymethyl methacrylate, bentonite, zirconium silicate, and synthetic resin (compounding amount is usually 20
~60%), cellulose derivatives such as carrageenan, sodium carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose, sodium carboxymethyl hydroxyethyl cellulose 1 alkali metal alginates such as sodium alginate, alginic propylene glycol ester, xanthan gum, gum tragacanth, gum karaya, arabic Gums such as gum,
Binder such as synthetic binder such as polyvinyl alcohol 1 polyacrylate, carboxyvinyl polymer, polyvinyl pyrrolidone, inorganic binder such as silica gel, aluminum silica gel, Veegum, Laponite etc. (in the amount usually 0.3~ 5%), thickening agents such as sorbitol, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylit, malnut, luffit (compounding amount usually 10-70%) , Sodium lauryl sal heptaate, Sodium myristylsa/I/phenoglyceride sulfonate, Sodium coconut monoglyceride sulfonate, etc., where the number of carbon atoms in the fatty acid group is 10 or more
Water-soluble salts of higher fatty acid monoglyceride sulfonate having 18 carbon atoms, higher fatty acid sodium monoglyceride monosulfate, olefin sulfonate, paraffin sulfonate and other anion activators, stearyl monoglyceride, sucrose mono- and dilaurate, etc. in which the number of carbon atoms in the fatty acid group is 12 to 18 sucrose fatty acid ester, lactose fatty acid ester, lactitol fatty acid ester,
Maltitol fatty acid ester, stearic acid monoglypeptide, polyoxyethylene sorbitan monolaurate, polyoxyethylene hardening and mustard oil, sorbitan monostearate condensate with about 60% ethylene glycol added, polymer of ethylene oxide and propylene oxide and nonionic activators such as derivatives such as polyoxyethylene polyoxybrobylene monolauryl ester,
Surfactants such as betaine type and amino acid type amphoteric active agents (compounding amount usually θ ~ 7%), as well as menthol, carvone, anethole, eugenol/'hosuruti/l/methyl acid 1 spearmint oil, peppermint oil, Lemon oil, orange oil, sage oil, rose! Flavoring agents such as li oil, cinnamon oil, viment oil, cinnamon leaf oil, wintergreen oil, clove oil, eucalyptus oil, strawberry flavor, orange flavor, lemon flavor, apple flavor, banana flavor, pineapple flavor, etc. Flavor (compounding amount usually θ ~ 5%), sweeteners such as saccharin sodium, stevioside, neohesberidyl dihyde ν-calfine, glycyrrhizin, perillartine, p-methoxycinnamic aldehyde, sodium dihydroacetate, p-human oxymethyl benzoic Preservatives such as acid, p-acid, and druxibutylbenzoin acid may be added, and these necessary ingredients can be mixed with water and produced according to conventional methods.

In addition, when preparing the toothpaste composition of the present invention into a transparent toothpaste using a silica-based abrasive, hydrated amorphous silica such as precipitated silica, silica xerogel, silica aerogel, etc. In addition to using silica, a transparent vehicle containing a thickening agent, a binder, and water as main components and having almost the same refractive index as the silica-based abrasive is prepared, and this transparent vehicle and the silica-based abrasive are mixed. Transparent toothpaste can be obtained by doing this. In this case, as the monohydrated amorphous silica, precipitated silica is particularly preferably used, and the Sing content is 70% or more, preferably 90% or more,
Alkali/alkaline earth gold J11! Chemical content 0-5%,
Binding amount of oxides of metals such as aluminum, magnesium, calcium, etc. to S10□ θ~10%, preferably 0~f)%, adhesion moisture content drying loss 11t) 1~10%
with an average particle size of 0.5 to 80μ, more preferably 1
~15μ, specific surface area per y (BE:T method) 500W
l or less, more preferably 300i or less, refractive index 1.44
~1.47 and a liquid absorption amount of 0.6 to 1.814/9 are preferably used. Specifically, Huber in the United States
zoo 49, zeodent 11 g, 5yloid Ir-1, 6B from W, R, Grace, USA
, 74.244, UK J, 0rossfield &
1ie08yl ET z Germany of 130118 companies
Examples include 5ident 8.20 from Degussh. In addition, the amount of silica-based abrasive added to the total toothpaste is 1 to 1.
It is preferably 40%, particularly 5 to 80%.

In addition, the dentifrice composition of the present invention includes dextranase, amylase, protease, mutanase,
phosphatase, lysozyme, litectenzyme, etc.) alkali metal monofluorophosphates such as sodium monofluorophosphate and potassium monofluorophosphate; fluorine compounds such as sodium heptatide and stannous heptatide; stannous compounds such as Bipurine No. 1 #M, chlorhexidine salts such as chlorhexidine hydrochloride, polypropylene gluconate, copper polyprophyllin sodium,
Herbal medicines such as hinokitiol, ipcisin aminocabronic acid, tranexamic acid, ethanedihydroxydiphosphonate, allantoin chlorhydroxyaluminum, dihydrocholesterol, clycyrrhetinic acid, azulene, chamomile, chelating phosphoric acid compounds such as lipophile, glycerophosphate, etc. , sodium chloride, etc., or two or more compounds may be combined.

As described above, the dentifrice composition according to the present invention is a dentifrice composition containing macrogenic silica, in which ortholine 1 [one or more selected from polyphosphates and metaphosphates is added to 0% of the entire composition. By blending .01 to 0.5%, the astringency caused by bulk silica can be effectively suppressed, resulting in an excellent feeling of use.

Next, the effects of the present invention will be explained experimentally.

Examples Water extracts of each silica shown in Table 1 (10 g of silica/9 g of water)
θ)) of each phosphate shown in Table 1 at a constant rate of 1 t (0.1%
) was added, and the astringency suppressing effect of each phosphate was evaluated by comparing the astringency of the additive and the astringency after addition through a sensory test conducted by a panel of 10 experts.

The results are shown in Table 1. In addition, the sodium polyphosphate in Table 1 has sodium tripolyphosphate as a main component, with small amounts of sodium birophosphate and sodium trimetaphosphate mixed therein.

Table 1 The evaluation criteria are as follows.

Evaluation Criteria ◎Nirin #Astringency is greatly improved compared to MJ liquid before addition of salt. (Not astringent) ○Astringency has been improved compared to the extract before addition of diphosphate. (Slightly astringent, but not enough to cause a problem) △Astringency is slightly improved compared to the extract before addition of diphosphate.

×Astringency is not improved compared to the extract before addition of diphosphate. (Strongly astringent) From the results in Table 1, the astringency caused by large-scale silica can be suppressed by adding orthophosphates, polyphosphates, and metaphosphates, and polyphosphates and metaphosphates are particularly effective. It was discovered that

EXAMPLES Hereinafter, examples and comparative examples will be shown to specifically illustrate the present invention.

(Examples 1 to 4, Comparative Examples) Toothpastes with the following formulations were prepared using the various phosphates shown in Table 2, and their astringency was sensory evaluated using a panel of 10 experts. It is shown in Table 2.The evaluation criteria are as follows.

Evaluation Criteria ◎: Compared to Comparative Example 1, the astringency is greatly improved. (Not astringent) O: The astringent taste is improved compared to the toothpaste of the comparative example. (
(Slightly astringent, but not bad enough to be a problem) △: The astringent taste is slightly improved compared to the toothpaste of the comparative example.

×: Astringency is not improved compared to the toothpaste of the comparative example.

(Strongly astringent) Formulation Examples 1 to 4 Relatively precipitated silica 20% 20% Adult silica (Cab-0-ail) 8 886%
Glycerin 28 2870% Sorbitol 42 42 Polyethylene glycol 400 5 5
Rikihachi 4-Hishimethylcellulose Sodium 1
1 Sodium lauryl buclate
1.5 1.5 Phosphate shown in Table 2 0.1-saccharin sodium
0.1 0.1 fragrance
1.0 1.0 Table 2 [Examples 5 to 8] Dentures Table 3 Note: The same sodium polyphosphate as in the experimental example was used.

Sensory bond value evaluated by 10 expert panels 1 Example 5
All of the toothpastes No. 8 to 8 had no astringent taste and had good flavor.

Note that the product containing 1.5% sodium polyphosphate had poor flavor and poor feeling of use.

All of the toothpastes of Examples g7AJ9 to 17 had no astringency and had good flavor and feeling of use.

In addition, the toothpastes of Examples 9.10.12.1B and 15 to 17 used Cab-0-8il as the major silica,
Furthermore, the toothpastes of Examples 11 and 14 used pentaeroisil as the macrogenic silica.

Applicant Lion Corporation Agent: Patent Attorney Takashi Kojima l Patent attorney Hanyo Takahata

Claims (1)

[Scope of Claims] t. In a dentifrice composition containing pyrogenic silica, one or more phosphates selected from orthophosphates, polyphosphates, and metaphosphates are added to 0.0% of the entire composition. 01
A dentifrice composition characterized by containing ~1% by weight. 2 Phosphate is potassium bier phosphate, bis> fi
1 type or 2 types selected from ll + thorium, trisodium billphosphate, disodium billphosphate, sodium polyphosphate, sodium tripolyphosphate, potassium tripolyphosphate, potassium metaphosphate, sodium trimetaphosphate, sodium hexametaphosphate, and sodium heptametaphosphate The dentifrice composition according to claim 1, which is the above.