JPS5798228A - Biphenyl derivative - Google Patents
Biphenyl derivativeInfo
- Publication number
- JPS5798228A JPS5798228A JP17505580A JP17505580A JPS5798228A JP S5798228 A JPS5798228 A JP S5798228A JP 17505580 A JP17505580 A JP 17505580A JP 17505580 A JP17505580 A JP 17505580A JP S5798228 A JPS5798228 A JP S5798228A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- derivative
- halogen
- formula iii
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:A compound of formulaI(R1 is H, aryl or lower alkyl; X and Y are H, CH3, halogen or CF3, except when both X and Y are H, and either one of X and Y is H, the other being 4'-bromo, 4'-chloro or 2'-fluoro).
EXAMPLE: 2-Methoxy-4'-fluorobiphenyl.
USE: An antimicrobial agent and an intermediate for a biphenylylacetic acid derivative having the analgesic anti-inflammatory and antipyretic actions.
PROCESS: The compound of formulaIis obtained by the following methods: (A) An aniline derivative of formula II is diazotized and coupled with anisole. (B) A halogenobenzene derivative of formula III (Z is halogen) is reacted with an o-alkoxyhalogenobenzene derivative in the presence of a metallic complex. (C) The compound of formula III is condensed with 2-chlorocyclohexanone and then converted into an aromatic compound.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17505580A JPS5798228A (en) | 1980-12-10 | 1980-12-10 | Biphenyl derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17505580A JPS5798228A (en) | 1980-12-10 | 1980-12-10 | Biphenyl derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5798228A true JPS5798228A (en) | 1982-06-18 |
Family
ID=15989437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17505580A Pending JPS5798228A (en) | 1980-12-10 | 1980-12-10 | Biphenyl derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5798228A (en) |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100384193B1 (en) * | 2000-11-14 | 2003-06-09 | 주식회사 에스엔테크 | Preparation of 2,4-halogen substituted biphenyl derivatives |
WO2004017920A3 (en) * | 2002-08-23 | 2004-07-08 | Univ Connecticut | Novel biphenyl and biphenyl-like cannabinoids |
US6900236B1 (en) | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
US6939977B2 (en) | 1998-05-04 | 2005-09-06 | The University Of Connecticut | Analgesic and immunomodulatory cannabinoids |
US6943266B1 (en) | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
US6995187B1 (en) | 1999-10-18 | 2006-02-07 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
US7057076B2 (en) | 2001-07-13 | 2006-06-06 | University Of Connecticut | Bicyclic and tricyclic cannabinoids |
US7119108B1 (en) | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
US7173027B2 (en) | 2001-01-29 | 2007-02-06 | University Of Connecticut | Receptor selective cannabimimetic aminoalkylindoles |
US7183313B2 (en) | 2002-08-23 | 2007-02-27 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
US7393842B2 (en) | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
US7589220B2 (en) | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
US7897598B2 (en) | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
US8084467B2 (en) | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS491541A (en) * | 1972-05-02 | 1974-01-08 |
-
1980
- 1980-12-10 JP JP17505580A patent/JPS5798228A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS491541A (en) * | 1972-05-02 | 1974-01-08 |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6939977B2 (en) | 1998-05-04 | 2005-09-06 | The University Of Connecticut | Analgesic and immunomodulatory cannabinoids |
US7897598B2 (en) | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
US7589220B2 (en) | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
US6943266B1 (en) | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
US7119108B1 (en) | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US6995187B1 (en) | 1999-10-18 | 2006-02-07 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
US6900236B1 (en) | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
US8084467B2 (en) | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
KR100384193B1 (en) * | 2000-11-14 | 2003-06-09 | 주식회사 에스엔테크 | Preparation of 2,4-halogen substituted biphenyl derivatives |
US7173027B2 (en) | 2001-01-29 | 2007-02-06 | University Of Connecticut | Receptor selective cannabimimetic aminoalkylindoles |
US7057076B2 (en) | 2001-07-13 | 2006-06-06 | University Of Connecticut | Bicyclic and tricyclic cannabinoids |
US7393842B2 (en) | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
US7183313B2 (en) | 2002-08-23 | 2007-02-27 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
WO2004017920A3 (en) * | 2002-08-23 | 2004-07-08 | Univ Connecticut | Novel biphenyl and biphenyl-like cannabinoids |
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