JPS572242A - Preparation of 2-bromo-2-nitro-1,3-propanediol - Google Patents

Preparation of 2-bromo-2-nitro-1,3-propanediol

Info

Publication number
JPS572242A
JPS572242A JP7634280A JP7634280A JPS572242A JP S572242 A JPS572242 A JP S572242A JP 7634280 A JP7634280 A JP 7634280A JP 7634280 A JP7634280 A JP 7634280A JP S572242 A JPS572242 A JP S572242A
Authority
JP
Japan
Prior art keywords
water
methanol
ethanol
give
mixed solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7634280A
Other languages
Japanese (ja)
Other versions
JPH0223535B2 (en
Inventor
Michio Harakawa
Osamu Takatsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kumiai Chemical Industry Co Ltd
Original Assignee
Kumiai Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kumiai Chemical Industry Co Ltd filed Critical Kumiai Chemical Industry Co Ltd
Priority to JP7634280A priority Critical patent/JPS572242A/en
Publication of JPS572242A publication Critical patent/JPS572242A/en
Publication of JPH0223535B2 publication Critical patent/JPH0223535B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound in high purity and in high yield, by reacting nitromethane with formaldehyde using a mixed solvent or water and methanol or ethanol and utilizing an alkali hydroxide both for a catalyst and a salt-forming substance, followed by bromination.
CONSTITUTION: 1 Mole nitromethane is reacted with 2 or more mole formaldehyde in a mixed solvent of water and methanol or ethanol (a weight ratio of alcohol/ water 0.5W4) in the presence of an alkali hydroxide, to give a reaction product, which is brominated to give the desired compound.
EFFECT: The reaction is carried out relatively mildly and smoothly with easy control and at low cost.
COPYRIGHT: (C)1982,JPO&Japio
JP7634280A 1980-06-06 1980-06-06 Preparation of 2-bromo-2-nitro-1,3-propanediol Granted JPS572242A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7634280A JPS572242A (en) 1980-06-06 1980-06-06 Preparation of 2-bromo-2-nitro-1,3-propanediol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7634280A JPS572242A (en) 1980-06-06 1980-06-06 Preparation of 2-bromo-2-nitro-1,3-propanediol

Publications (2)

Publication Number Publication Date
JPS572242A true JPS572242A (en) 1982-01-07
JPH0223535B2 JPH0223535B2 (en) 1990-05-24

Family

ID=13602679

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7634280A Granted JPS572242A (en) 1980-06-06 1980-06-06 Preparation of 2-bromo-2-nitro-1,3-propanediol

Country Status (1)

Country Link
JP (1) JPS572242A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723044A (en) * 1985-06-17 1988-02-02 Permachem Asia, Ltd. Production of dibromonitro compound
JP2011513297A (en) * 2008-02-28 2011-04-28 ブロミン・コンパウンズ・リミテツド Production method of bronopol
CN102850226A (en) * 2012-10-15 2013-01-02 潍坊裕凯化工有限公司 Method for synthesizing and preparing bronopol by one step
CN104926661A (en) * 2015-05-27 2015-09-23 天津市职业大学 Synthetic method for bronopol
CN110627646A (en) * 2019-10-18 2019-12-31 利尔化学股份有限公司 Preparation method of 5-fluoro-2-nitrophenol
CN113801024A (en) * 2021-10-18 2021-12-17 天津长芦海晶集团有限公司 Method for synthesizing bronopol from bromine chloride

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4920761A (en) * 1972-06-20 1974-02-23

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4920761A (en) * 1972-06-20 1974-02-23

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723044A (en) * 1985-06-17 1988-02-02 Permachem Asia, Ltd. Production of dibromonitro compound
JP2011513297A (en) * 2008-02-28 2011-04-28 ブロミン・コンパウンズ・リミテツド Production method of bronopol
CN103396317B (en) * 2008-02-28 2016-04-27 溴化合物有限公司 Prepare the method for bronopol
CN102850226A (en) * 2012-10-15 2013-01-02 潍坊裕凯化工有限公司 Method for synthesizing and preparing bronopol by one step
CN104926661A (en) * 2015-05-27 2015-09-23 天津市职业大学 Synthetic method for bronopol
CN110627646A (en) * 2019-10-18 2019-12-31 利尔化学股份有限公司 Preparation method of 5-fluoro-2-nitrophenol
CN113801024A (en) * 2021-10-18 2021-12-17 天津长芦海晶集团有限公司 Method for synthesizing bronopol from bromine chloride

Also Published As

Publication number Publication date
JPH0223535B2 (en) 1990-05-24

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