JPS572242A - Preparation of 2-bromo-2-nitro-1,3-propanediol - Google Patents
Preparation of 2-bromo-2-nitro-1,3-propanediolInfo
- Publication number
- JPS572242A JPS572242A JP7634280A JP7634280A JPS572242A JP S572242 A JPS572242 A JP S572242A JP 7634280 A JP7634280 A JP 7634280A JP 7634280 A JP7634280 A JP 7634280A JP S572242 A JPS572242 A JP S572242A
- Authority
- JP
- Japan
- Prior art keywords
- water
- methanol
- ethanol
- give
- mixed solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To obtain the titled compound in high purity and in high yield, by reacting nitromethane with formaldehyde using a mixed solvent or water and methanol or ethanol and utilizing an alkali hydroxide both for a catalyst and a salt-forming substance, followed by bromination.
CONSTITUTION: 1 Mole nitromethane is reacted with 2 or more mole formaldehyde in a mixed solvent of water and methanol or ethanol (a weight ratio of alcohol/ water 0.5W4) in the presence of an alkali hydroxide, to give a reaction product, which is brominated to give the desired compound.
EFFECT: The reaction is carried out relatively mildly and smoothly with easy control and at low cost.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7634280A JPS572242A (en) | 1980-06-06 | 1980-06-06 | Preparation of 2-bromo-2-nitro-1,3-propanediol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7634280A JPS572242A (en) | 1980-06-06 | 1980-06-06 | Preparation of 2-bromo-2-nitro-1,3-propanediol |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS572242A true JPS572242A (en) | 1982-01-07 |
JPH0223535B2 JPH0223535B2 (en) | 1990-05-24 |
Family
ID=13602679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7634280A Granted JPS572242A (en) | 1980-06-06 | 1980-06-06 | Preparation of 2-bromo-2-nitro-1,3-propanediol |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS572242A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4723044A (en) * | 1985-06-17 | 1988-02-02 | Permachem Asia, Ltd. | Production of dibromonitro compound |
JP2011513297A (en) * | 2008-02-28 | 2011-04-28 | ブロミン・コンパウンズ・リミテツド | Production method of bronopol |
CN102850226A (en) * | 2012-10-15 | 2013-01-02 | 潍坊裕凯化工有限公司 | Method for synthesizing and preparing bronopol by one step |
CN104926661A (en) * | 2015-05-27 | 2015-09-23 | 天津市职业大学 | Synthetic method for bronopol |
CN110627646A (en) * | 2019-10-18 | 2019-12-31 | 利尔化学股份有限公司 | Preparation method of 5-fluoro-2-nitrophenol |
CN113801024A (en) * | 2021-10-18 | 2021-12-17 | 天津长芦海晶集团有限公司 | Method for synthesizing bronopol from bromine chloride |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4920761A (en) * | 1972-06-20 | 1974-02-23 |
-
1980
- 1980-06-06 JP JP7634280A patent/JPS572242A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4920761A (en) * | 1972-06-20 | 1974-02-23 |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4723044A (en) * | 1985-06-17 | 1988-02-02 | Permachem Asia, Ltd. | Production of dibromonitro compound |
JP2011513297A (en) * | 2008-02-28 | 2011-04-28 | ブロミン・コンパウンズ・リミテツド | Production method of bronopol |
CN103396317B (en) * | 2008-02-28 | 2016-04-27 | 溴化合物有限公司 | Prepare the method for bronopol |
CN102850226A (en) * | 2012-10-15 | 2013-01-02 | 潍坊裕凯化工有限公司 | Method for synthesizing and preparing bronopol by one step |
CN104926661A (en) * | 2015-05-27 | 2015-09-23 | 天津市职业大学 | Synthetic method for bronopol |
CN110627646A (en) * | 2019-10-18 | 2019-12-31 | 利尔化学股份有限公司 | Preparation method of 5-fluoro-2-nitrophenol |
CN113801024A (en) * | 2021-10-18 | 2021-12-17 | 天津长芦海晶集团有限公司 | Method for synthesizing bronopol from bromine chloride |
Also Published As
Publication number | Publication date |
---|---|
JPH0223535B2 (en) | 1990-05-24 |
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