JPS57167919A - Preventing agent for intraperitoneal adhesion - Google Patents
Preventing agent for intraperitoneal adhesionInfo
- Publication number
- JPS57167919A JPS57167919A JP5263981A JP5263981A JPS57167919A JP S57167919 A JPS57167919 A JP S57167919A JP 5263981 A JP5263981 A JP 5263981A JP 5263981 A JP5263981 A JP 5263981A JP S57167919 A JPS57167919 A JP S57167919A
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- sodium alginate
- adhesion
- laparotomy
- preventing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A preventing agent for the intraperitoneal adhesion, containing an aqueous solution of sodium alginate as a principal component, and capable of showing the improved preventing effect on adhesion by the direct injection into the operative site after the laparotomy.
CONSTITUTION: An aqueous solution of sodium alginate, preferably in a concentration of bout 2W8wt%, is directly injected into an operative site of laparotomy to prevent the adhesion. The sodium alginate is present in a brown alga, e.g. sea tangle, and a sodium salt of a polysaccharide constituted of D-mannuronic acid and L-guluronic acid, and the polymerization degree is preferably about 50W1,500. The aqueous solution is preferably isotonized with the body fluid, and adjusted by using Ringer's solution, etc. In the case of the usual laparotomy, an aqueous solution of the sodium alginate in a volume preferably about 30W300ml is injected.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5263981A JPS57167919A (en) | 1981-04-07 | 1981-04-07 | Preventing agent for intraperitoneal adhesion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5263981A JPS57167919A (en) | 1981-04-07 | 1981-04-07 | Preventing agent for intraperitoneal adhesion |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57167919A true JPS57167919A (en) | 1982-10-16 |
JPS648603B2 JPS648603B2 (en) | 1989-02-14 |
Family
ID=12920397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5263981A Granted JPS57167919A (en) | 1981-04-07 | 1981-04-07 | Preventing agent for intraperitoneal adhesion |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57167919A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04261664A (en) * | 1990-07-09 | 1992-09-17 | Biomatrix Inc | Vitally adaptive viscoelastic gel slurry and making and use thereof |
AU671114B2 (en) * | 1992-06-30 | 1996-08-15 | Stryker Technologies Corporation | Preventing tissue adhesion using (in situ) modification of alginate |
KR20010107067A (en) * | 2000-05-25 | 2001-12-07 | 김정식 | A conglutination inhibitor |
WO2004105737A3 (en) * | 2003-05-30 | 2005-06-09 | Arc Pharmaceuticals Inc | Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents |
JP2009014096A (en) * | 2007-07-04 | 2009-01-22 | Nsk Ltd | Bearing device and assembling method of bearing device |
WO2012085609A1 (en) | 2010-12-20 | 2012-06-28 | Dept. Of Pathobiology | Treatment of osteoarthritis by continuous intra-articular injection of alginate gel |
CN104771639A (en) * | 2013-10-17 | 2015-07-15 | 常鲁 | Preparation method of medicine for external postoperative bowel dysfunction |
KR20160138379A (en) | 2014-03-31 | 2016-12-05 | 도레이 카부시키가이샤 | Multilayer sheet, integrated sheet using same, and manufacturing method therefor |
-
1981
- 1981-04-07 JP JP5263981A patent/JPS57167919A/en active Granted
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04261664A (en) * | 1990-07-09 | 1992-09-17 | Biomatrix Inc | Vitally adaptive viscoelastic gel slurry and making and use thereof |
AU671114B2 (en) * | 1992-06-30 | 1996-08-15 | Stryker Technologies Corporation | Preventing tissue adhesion using (in situ) modification of alginate |
KR20010107067A (en) * | 2000-05-25 | 2001-12-07 | 김정식 | A conglutination inhibitor |
WO2004105737A3 (en) * | 2003-05-30 | 2005-06-09 | Arc Pharmaceuticals Inc | Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents |
JP2009014096A (en) * | 2007-07-04 | 2009-01-22 | Nsk Ltd | Bearing device and assembling method of bearing device |
WO2012085609A1 (en) | 2010-12-20 | 2012-06-28 | Dept. Of Pathobiology | Treatment of osteoarthritis by continuous intra-articular injection of alginate gel |
CN104771639A (en) * | 2013-10-17 | 2015-07-15 | 常鲁 | Preparation method of medicine for external postoperative bowel dysfunction |
KR20160138379A (en) | 2014-03-31 | 2016-12-05 | 도레이 카부시키가이샤 | Multilayer sheet, integrated sheet using same, and manufacturing method therefor |
US10786603B2 (en) | 2014-03-31 | 2020-09-29 | Toray Industries, Inc. | Multilayer sheet, integrated sheet using same, and manufacturing method therefor |
Also Published As
Publication number | Publication date |
---|---|
JPS648603B2 (en) | 1989-02-14 |
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