JPS5663961A - Novel isoindoline derivative and its preparation - Google Patents

Novel isoindoline derivative and its preparation

Info

Publication number
JPS5663961A
JPS5663961A JP12799079A JP12799079A JPS5663961A JP S5663961 A JPS5663961 A JP S5663961A JP 12799079 A JP12799079 A JP 12799079A JP 12799079 A JP12799079 A JP 12799079A JP S5663961 A JPS5663961 A JP S5663961A
Authority
JP
Japan
Prior art keywords
formula
preparation
isoindoline derivative
compound
expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12799079A
Other languages
Japanese (ja)
Inventor
Tsutomu Kameyama
Noboru Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP12799079A priority Critical patent/JPS5663961A/en
Publication of JPS5663961A publication Critical patent/JPS5663961A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:An isoindoline derivative expressed by formula I (R1 and R2 are Hs or halogens; R3 and R4 are lower alkyls, or together with N may form pyrrolidine , piperidine or morpholine; ring A is formula II, III or IV).
EXAMPLE: 2-[ 4-( β-pyrrolidinoethoxy )phenyl ]-4,5,6,7-tetrahydroisoindolin-1-one.
USE: An analgesic agent.
PROCESS: A compound expressed by formula VI or a salt thereof, e.g. sodium salt, is refluxed with a compound expressed by formula VII (X is halogen) in water or an organic solvent, e.g. acetone, preferably in the presence of a base, e.g. NaOH, under heating to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP12799079A 1979-10-05 1979-10-05 Novel isoindoline derivative and its preparation Pending JPS5663961A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12799079A JPS5663961A (en) 1979-10-05 1979-10-05 Novel isoindoline derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12799079A JPS5663961A (en) 1979-10-05 1979-10-05 Novel isoindoline derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5663961A true JPS5663961A (en) 1981-05-30

Family

ID=14973717

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12799079A Pending JPS5663961A (en) 1979-10-05 1979-10-05 Novel isoindoline derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5663961A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0644655U (en) * 1992-11-26 1994-06-14 隆 松下 Seat belt fixing device
EP1467979A2 (en) * 2001-12-19 2004-10-20 Bristol-Myers Squibb Company FUSED HETEROCYCLIC COMPOUNDS AND ANALOGS THEREOF: MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION
WO2004089897A1 (en) * 2003-04-07 2004-10-21 Glaxo Group Limited Compounds having activity at 5ht2c receptor and uses thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0644655U (en) * 1992-11-26 1994-06-14 隆 松下 Seat belt fixing device
EP1467979A2 (en) * 2001-12-19 2004-10-20 Bristol-Myers Squibb Company FUSED HETEROCYCLIC COMPOUNDS AND ANALOGS THEREOF: MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION
EP1467979A4 (en) * 2001-12-19 2006-03-15 Bristol Myers Squibb Co Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function
WO2004089897A1 (en) * 2003-04-07 2004-10-21 Glaxo Group Limited Compounds having activity at 5ht2c receptor and uses thereof
JP2006522065A (en) * 2003-04-07 2006-09-28 グラクソ　グループ　リミテッド Compounds having 5-HT2C receptor activity and uses thereof

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