JPS5651411A - Microcapsule preparation having magnetism - Google Patents

Microcapsule preparation having magnetism

Info

Publication number
JPS5651411A
JPS5651411A JP12733779A JP12733779A JPS5651411A JP S5651411 A JPS5651411 A JP S5651411A JP 12733779 A JP12733779 A JP 12733779A JP 12733779 A JP12733779 A JP 12733779A JP S5651411 A JPS5651411 A JP S5651411A
Authority
JP
Japan
Prior art keywords
particles
drug component
organic polymer
powder
magnetic field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12733779A
Other languages
Japanese (ja)
Inventor
Tetsuo Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP12733779A priority Critical patent/JPS5651411A/en
Publication of JPS5651411A publication Critical patent/JPS5651411A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE:To provide a microcapsule preparation which has both sustained activity and slow-releasability of the drug component and can be guided with magnetic field, by coating a drug component with an organic polymer containing ferromagnetic particles. CONSTITUTION:Particles of drug component coated with an organic polymer and firmly attached with ferromagnetic particles, are obtained by (1) dissolving an organic polymer (e.g. ethylcellulose, gelatin, albumin, etc.) and optionally an adjuvant in an organic solvent, (2) adding the drug component and ferromagnetic powders (e.g. ferrite powder, Pt-Co powder, iron powder, etc.) to the hot solution thus obtained, and (3) stirring and slowly cooling the mixture. The coated particles are washed with a solution of a surface active agent (e.g. HCO-60, Tween 80, etc.) to obtain the objective product. When administered in the body, the particles can be guided directly to the diseased part with the outer magnetic field, thereby exhibiting the maximum remedying effect with little side effects.
JP12733779A 1979-10-04 1979-10-04 Microcapsule preparation having magnetism Pending JPS5651411A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12733779A JPS5651411A (en) 1979-10-04 1979-10-04 Microcapsule preparation having magnetism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12733779A JPS5651411A (en) 1979-10-04 1979-10-04 Microcapsule preparation having magnetism

Publications (1)

Publication Number Publication Date
JPS5651411A true JPS5651411A (en) 1981-05-09

Family

ID=14957419

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12733779A Pending JPS5651411A (en) 1979-10-04 1979-10-04 Microcapsule preparation having magnetism

Country Status (1)

Country Link
JP (1) JPS5651411A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163821A (en) * 1984-02-03 1985-08-26 Tdk Corp Carrier for pharmaceutical containing ferrite particle
JPH029813A (en) * 1988-02-24 1990-01-12 Dainichiseika Color & Chem Mfg Co Ltd Formulation containing magnetic material and use thereof
DE19606804A1 (en) * 1996-02-23 1997-08-28 Peter Dr Borrmann Planned release of active substance
WO1999020245A1 (en) * 1997-10-17 1999-04-29 Institut für Physikalische Hochtechnologie e.V. Marker for intestinal diagnosis and intestinal therapy
EP0928611A1 (en) * 1996-06-10 1999-07-14 Nittetsu Mining Co., Ltd. Medical powder
JPWO2006035550A1 (en) * 2004-09-28 2008-05-15 国立大学法人大阪大学 Three-dimensional guidance apparatus and method, and drug delivery system
JP2009038919A (en) * 2007-08-02 2009-02-19 Viscas Corp Method for processing end portion of external semi-conducting layer of cv cable and tool
EP1668424A4 (en) * 2003-09-12 2009-11-25 Onkor Pharmaceuticals Inc Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
WO2010129184A3 (en) * 2009-04-28 2011-09-22 Boston Scientific Scimed, Inc. Magnetic particles for delivering therapeutic agent to a target location

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4929679A (en) * 1972-07-11 1974-03-16
JPS5464626A (en) * 1977-08-01 1979-05-24 Univ Northwestern Support for dosing into vessel being present locally by magnetic force and production thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4929679A (en) * 1972-07-11 1974-03-16
JPS5464626A (en) * 1977-08-01 1979-05-24 Univ Northwestern Support for dosing into vessel being present locally by magnetic force and production thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163821A (en) * 1984-02-03 1985-08-26 Tdk Corp Carrier for pharmaceutical containing ferrite particle
JPH029813A (en) * 1988-02-24 1990-01-12 Dainichiseika Color & Chem Mfg Co Ltd Formulation containing magnetic material and use thereof
JPH0761936B2 (en) * 1988-02-24 1995-07-05 大日精化工業株式会社 Preparation containing magnetic substance
DE19606804A1 (en) * 1996-02-23 1997-08-28 Peter Dr Borrmann Planned release of active substance
EP0928611A1 (en) * 1996-06-10 1999-07-14 Nittetsu Mining Co., Ltd. Medical powder
EP0928611A4 (en) * 1996-06-10 1999-12-15 Nittetsu Mining Co Ltd Medical powder
WO1999020245A1 (en) * 1997-10-17 1999-04-29 Institut für Physikalische Hochtechnologie e.V. Marker for intestinal diagnosis and intestinal therapy
EP1668424A4 (en) * 2003-09-12 2009-11-25 Onkor Pharmaceuticals Inc Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
JPWO2006035550A1 (en) * 2004-09-28 2008-05-15 国立大学法人大阪大学 Three-dimensional guidance apparatus and method, and drug delivery system
JP2009038919A (en) * 2007-08-02 2009-02-19 Viscas Corp Method for processing end portion of external semi-conducting layer of cv cable and tool
WO2010129184A3 (en) * 2009-04-28 2011-09-22 Boston Scientific Scimed, Inc. Magnetic particles for delivering therapeutic agent to a target location
US8550089B2 (en) 2009-04-28 2013-10-08 Boston Scientific Scimed, Inc. Magnetic particles for delivering therapeutic agent to a target location

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