JPS56169622A - Method of making solid preparation from oily substance - Google Patents

Method of making solid preparation from oily substance

Info

Publication number
JPS56169622A
JPS56169622A JP7470180A JP7470180A JPS56169622A JP S56169622 A JPS56169622 A JP S56169622A JP 7470180 A JP7470180 A JP 7470180A JP 7470180 A JP7470180 A JP 7470180A JP S56169622 A JPS56169622 A JP S56169622A
Authority
JP
Japan
Prior art keywords
oily substance
solid preparation
water
substance
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7470180A
Other languages
Japanese (ja)
Other versions
JPH0129764B2 (en
Inventor
Sumio Hatsuya
Morita Riyoushiyou
Akira Wako
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Priority to JP7470180A priority Critical patent/JPS56169622A/en
Publication of JPS56169622A publication Critical patent/JPS56169622A/en
Publication of JPH0129764B2 publication Critical patent/JPH0129764B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)

Abstract

PURPOSE: An oily substance is made into a preparation by combining it with a specific nonionic surfactant and a specific hydrophilic solid substance, thus facilitating the production of the solid preparation that smoothly releases the active components.
CONSTITUTION: An oily substance such as dimethylpolysiloxane, α-tocopherol acetate and a nonionic surfactant with a HLB of more than 7 are adsorbed on a powder of, e.g., magnesium aluminum metasilicate. Then, a water-soluble solid substance melting at higher than 50°C such as polyethylene glycol 6,000 is added to the composition and they are kneaded under heating up to higher than the melting point. Further, a diluent is added thereto to give the objective solid preparation. Since it readily disintegrates and disperses in water to form the emulsion of the active principles in the oil-in-water form, the active components can be readily absorbed.
COPYRIGHT: (C)1981,JPO&Japio
JP7470180A 1980-06-03 1980-06-03 Method of making solid preparation from oily substance Granted JPS56169622A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7470180A JPS56169622A (en) 1980-06-03 1980-06-03 Method of making solid preparation from oily substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7470180A JPS56169622A (en) 1980-06-03 1980-06-03 Method of making solid preparation from oily substance

Publications (2)

Publication Number Publication Date
JPS56169622A true JPS56169622A (en) 1981-12-26
JPH0129764B2 JPH0129764B2 (en) 1989-06-14

Family

ID=13554786

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7470180A Granted JPS56169622A (en) 1980-06-03 1980-06-03 Method of making solid preparation from oily substance

Country Status (1)

Country Link
JP (1) JPS56169622A (en)

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2594693A1 (en) * 1986-02-24 1987-08-28 Farah Nabil New processes for preparing, from dry emulsions, solid oral dosage forms displaying modified and delayed release of their active principles
FR2648708A2 (en) * 1986-02-24 1990-12-28 Farah Nabil Solid and semi-solid pharmaceutical preparations affording modified release of their active principles, using the "dry emulsions" process
EP1297825A1 (en) * 2001-09-28 2003-04-02 McNEIL-PPC, INC. Simethicone solid oral dosage form
JP2005530835A (en) * 2002-06-25 2005-10-13 ニコックス エス エイ Oral pharmaceutical forms of liquid drugs with improved bioavailability
JP2011519886A (en) * 2008-05-09 2011-07-14 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Method for producing intermediate powder formulation and final solid dosage form under application of spray coagulation process
JP2013010713A (en) * 2011-06-29 2013-01-17 Tokyo Metropolitan Industrial Technology Research Institute Inorganic-organic composite particle, and method for producing the same
US9629807B2 (en) 2003-08-06 2017-04-25 Grünenthal GmbH Abuse-proofed dosage form
US9636303B2 (en) 2010-09-02 2017-05-02 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
US9655853B2 (en) 2012-02-28 2017-05-23 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
US9675610B2 (en) 2002-06-17 2017-06-13 Grünenthal GmbH Abuse-proofed dosage form
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
US9750701B2 (en) 2008-01-25 2017-09-05 Grünenthal GmbH Pharmaceutical dosage form
US9855263B2 (en) 2015-04-24 2018-01-02 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
US9913814B2 (en) 2014-05-12 2018-03-13 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
US9925146B2 (en) 2009-07-22 2018-03-27 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US10058548B2 (en) 2003-08-06 2018-08-28 Grünenthal GmbH Abuse-proofed dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US10080721B2 (en) 2009-07-22 2018-09-25 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
US10130591B2 (en) 2003-08-06 2018-11-20 Grünenthal GmbH Abuse-proofed dosage form
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
US10201502B2 (en) 2011-07-29 2019-02-12 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
US10300141B2 (en) 2010-09-02 2019-05-28 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
US10335373B2 (en) 2012-04-18 2019-07-02 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10449547B2 (en) 2013-11-26 2019-10-22 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
US10695297B2 (en) 2011-07-29 2020-06-30 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US10729658B2 (en) 2005-02-04 2020-08-04 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US11224576B2 (en) 2003-12-24 2022-01-18 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US11844865B2 (en) 2004-07-01 2023-12-19 Grünenthal GmbH Abuse-proofed oral dosage form

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4946585A (en) * 1972-09-11 1974-05-04

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4946585A (en) * 1972-09-11 1974-05-04

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2594693A1 (en) * 1986-02-24 1987-08-28 Farah Nabil New processes for preparing, from dry emulsions, solid oral dosage forms displaying modified and delayed release of their active principles
FR2648708A2 (en) * 1986-02-24 1990-12-28 Farah Nabil Solid and semi-solid pharmaceutical preparations affording modified release of their active principles, using the "dry emulsions" process
EP1297825A1 (en) * 2001-09-28 2003-04-02 McNEIL-PPC, INC. Simethicone solid oral dosage form
AU2002301259B2 (en) * 2001-09-28 2009-01-22 Mcneil-Ppc, Inc. Simethicone solid oral dosage form
AU2002301259C1 (en) * 2001-09-28 2009-07-23 Mcneil-Ppc, Inc. Simethicone solid oral dosage form
US10369109B2 (en) 2002-06-17 2019-08-06 Grünenthal GmbH Abuse-proofed dosage form
US9675610B2 (en) 2002-06-17 2017-06-13 Grünenthal GmbH Abuse-proofed dosage form
JP2005530835A (en) * 2002-06-25 2005-10-13 ニコックス エス エイ Oral pharmaceutical forms of liquid drugs with improved bioavailability
US9629807B2 (en) 2003-08-06 2017-04-25 Grünenthal GmbH Abuse-proofed dosage form
US10130591B2 (en) 2003-08-06 2018-11-20 Grünenthal GmbH Abuse-proofed dosage form
US10058548B2 (en) 2003-08-06 2018-08-28 Grünenthal GmbH Abuse-proofed dosage form
US11224576B2 (en) 2003-12-24 2022-01-18 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US11844865B2 (en) 2004-07-01 2023-12-19 Grünenthal GmbH Abuse-proofed oral dosage form
US10675278B2 (en) 2005-02-04 2020-06-09 Grünenthal GmbH Crush resistant delayed-release dosage forms
US10729658B2 (en) 2005-02-04 2020-08-04 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US9750701B2 (en) 2008-01-25 2017-09-05 Grünenthal GmbH Pharmaceutical dosage form
JP2011519886A (en) * 2008-05-09 2011-07-14 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Method for producing intermediate powder formulation and final solid dosage form under application of spray coagulation process
US9161917B2 (en) 2008-05-09 2015-10-20 Grünenthal GmbH Process for the preparation of a solid dosage form, in particular a tablet, for pharmaceutical use and process for the preparation of a precursor for a solid dosage form, in particular a tablet
US9925146B2 (en) 2009-07-22 2018-03-27 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US10080721B2 (en) 2009-07-22 2018-09-25 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
US10493033B2 (en) 2009-07-22 2019-12-03 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US9636303B2 (en) 2010-09-02 2017-05-02 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
US10300141B2 (en) 2010-09-02 2019-05-28 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
JP2013010713A (en) * 2011-06-29 2013-01-17 Tokyo Metropolitan Industrial Technology Research Institute Inorganic-organic composite particle, and method for producing the same
US10864164B2 (en) 2011-07-29 2020-12-15 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US10201502B2 (en) 2011-07-29 2019-02-12 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
US10695297B2 (en) 2011-07-29 2020-06-30 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US9655853B2 (en) 2012-02-28 2017-05-23 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
US10335373B2 (en) 2012-04-18 2019-07-02 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
US10449547B2 (en) 2013-11-26 2019-10-22 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
US9913814B2 (en) 2014-05-12 2018-03-13 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
US9855263B2 (en) 2015-04-24 2018-01-02 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction

Also Published As

Publication number Publication date
JPH0129764B2 (en) 1989-06-14

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