JPS56122365A - Tetrazole derivative - Google Patents
Tetrazole derivativeInfo
- Publication number
- JPS56122365A JPS56122365A JP2570880A JP2570880A JPS56122365A JP S56122365 A JPS56122365 A JP S56122365A JP 2570880 A JP2570880 A JP 2570880A JP 2570880 A JP2570880 A JP 2570880A JP S56122365 A JPS56122365 A JP S56122365A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- cycloalkyl
- phenyl
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I [A is lower alkylene; R1 is lower alkyl, cycloalkyl, or phenyl; R2 is lower alkyl, cycloalkyl, phenyl, pyridyl, or group of formula II (E and B are N atom or -CH=; R3 is lower alkyl, cycloalkyl, or phenyl)].
EXAMPLE: 1-Methyl-5-(3-phenylthiopropyl)thio-1,2,3,4-tetrazole.
USE: Antiulcer agent.
PROCESS: The compound of formula I is prepared, e.g. by reacting the compound of formula R2SH with the compound of formula IV obtained by the reaction of the compound of formula III with the compound of formula X-A-X' (X and X' are halogen) in the presence of sodium iodide, etc., using a dehydrohalogenating agent (e.g. NaOH) at 50W150°C.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2570880A JPS56122365A (en) | 1980-03-01 | 1980-03-01 | Tetrazole derivative |
FI810571A FI73423C (en) | 1980-02-29 | 1981-02-24 | FRAMEWORK FOR THE FRAMEWORK OF PHARMACOLOGICAL VEHICLES TETRAZOLDERIVAT. |
AT81101352T ATE11047T1 (en) | 1980-02-29 | 1981-02-25 | TETRAZOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND ANTI-ULCER COMPOSITION CONTAINING THEM. |
EP81101352A EP0035228B1 (en) | 1980-02-29 | 1981-02-25 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same |
AU67638/81A AU537266B2 (en) | 1980-02-29 | 1981-02-25 | Tetrazole derivatives |
PT72569A PT72569B (en) | 1980-02-29 | 1981-02-25 | Tetrazole derivatives process for the preparation thereof and anti-ulcer composition |
DE8181101352T DE3167997D1 (en) | 1980-02-29 | 1981-02-25 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same |
DK088081A DK162524C (en) | 1980-02-29 | 1981-02-26 | ANALOGY PROCEDURE FOR THE PREPARATION OF 5-ALKYLTHIO-TETRAZOLD DERIVATIVES |
ES499930A ES8300723A1 (en) | 1980-02-29 | 1981-02-27 | 1,5-Di:substd. tetrazole derivs. - useful as antiulcer agents |
PH25282A PH17406A (en) | 1980-02-29 | 1981-02-27 | Tetrazole derivatives and anti-ulcer composition containing the same |
CA000372021A CA1162196A (en) | 1980-02-29 | 1981-02-27 | Tetrazole derivatives having prophylactic and therapeutic activities against peptic and duodenal ulcers |
US06/239,044 US4372953A (en) | 1980-02-29 | 1981-02-27 | Tetrazole derivatives, and anti-ulcer composition containing the same |
MX815964A MX157430A (en) | 1980-02-29 | 1981-02-27 | PROCEDURE FOR THE PREPARATION OF TETRAZOLE DERIVATIVES |
NO810675A NO166320C (en) | 1980-02-29 | 1981-02-27 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAZOLD DERIVATIVES. |
SU813252652A SU1212324A3 (en) | 1980-03-01 | 1981-02-27 | Method of producing tetrazole derivatives or their pharmaceutically acceptable acid-additive salts |
ES510404A ES510404A0 (en) | 1980-02-29 | 1982-03-12 | A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE. |
ES510403A ES510403A0 (en) | 1980-02-29 | 1982-03-12 | A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE. |
ES510405A ES510405A0 (en) | 1980-02-29 | 1982-03-12 | "A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE". |
ES520699A ES520699A0 (en) | 1980-02-29 | 1983-03-16 | A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE. |
ES520898A ES8405383A1 (en) | 1980-02-29 | 1983-03-23 | 1,5-Di:substd. tetrazole derivs. - useful as antiulcer agents |
ES83520900A ES520900A0 (en) | 1980-02-29 | 1983-03-23 | A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE. |
ES520899A ES520899A0 (en) | 1980-02-29 | 1983-03-23 | A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2570880A JPS56122365A (en) | 1980-03-01 | 1980-03-01 | Tetrazole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56122365A true JPS56122365A (en) | 1981-09-25 |
JPH0128022B2 JPH0128022B2 (en) | 1989-05-31 |
Family
ID=12173279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2570880A Granted JPS56122365A (en) | 1980-02-29 | 1980-03-01 | Tetrazole derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56122365A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5759877A (en) * | 1980-09-30 | 1982-04-10 | Otsuka Pharmaceut Co Ltd | Tetrazole derivative |
-
1980
- 1980-03-01 JP JP2570880A patent/JPS56122365A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5759877A (en) * | 1980-09-30 | 1982-04-10 | Otsuka Pharmaceut Co Ltd | Tetrazole derivative |
JPH023786B2 (en) * | 1980-09-30 | 1990-01-24 | Otsuka Pharma Co Ltd |
Also Published As
Publication number | Publication date |
---|---|
JPH0128022B2 (en) | 1989-05-31 |
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