JPS56122365A - Tetrazole derivative - Google Patents

Tetrazole derivative

Info

Publication number
JPS56122365A
JPS56122365A JP2570880A JP2570880A JPS56122365A JP S56122365 A JPS56122365 A JP S56122365A JP 2570880 A JP2570880 A JP 2570880A JP 2570880 A JP2570880 A JP 2570880A JP S56122365 A JPS56122365 A JP S56122365A
Authority
JP
Japan
Prior art keywords
formula
compound
cycloalkyl
phenyl
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2570880A
Other languages
Japanese (ja)
Other versions
JPH0128022B2 (en
Inventor
Minoru Uchida
Takao Nishi
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP2570880A priority Critical patent/JPS56122365A/en
Priority to FI810571A priority patent/FI73423C/en
Priority to AT81101352T priority patent/ATE11047T1/en
Priority to EP81101352A priority patent/EP0035228B1/en
Priority to AU67638/81A priority patent/AU537266B2/en
Priority to PT72569A priority patent/PT72569B/en
Priority to DE8181101352T priority patent/DE3167997D1/en
Priority to DK088081A priority patent/DK162524C/en
Priority to US06/239,044 priority patent/US4372953A/en
Priority to PH25282A priority patent/PH17406A/en
Priority to CA000372021A priority patent/CA1162196A/en
Priority to ES499930A priority patent/ES8300723A1/en
Priority to MX815964A priority patent/MX157430A/en
Priority to NO810675A priority patent/NO166320C/en
Priority to SU813252652A priority patent/SU1212324A3/en
Publication of JPS56122365A publication Critical patent/JPS56122365A/en
Priority to ES510405A priority patent/ES510405A0/en
Priority to ES510403A priority patent/ES510403A0/en
Priority to ES510404A priority patent/ES510404A0/en
Priority to ES520699A priority patent/ES520699A0/en
Priority to ES520898A priority patent/ES8405383A1/en
Priority to ES83520900A priority patent/ES520900A0/en
Priority to ES520899A priority patent/ES520899A0/en
Publication of JPH0128022B2 publication Critical patent/JPH0128022B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I [A is lower alkylene; R1 is lower alkyl, cycloalkyl, or phenyl; R2 is lower alkyl, cycloalkyl, phenyl, pyridyl, or group of formula II (E and B are N atom or -CH=; R3 is lower alkyl, cycloalkyl, or phenyl)].
EXAMPLE: 1-Methyl-5-(3-phenylthiopropyl)thio-1,2,3,4-tetrazole.
USE: Antiulcer agent.
PROCESS: The compound of formula I is prepared, e.g. by reacting the compound of formula R2SH with the compound of formula IV obtained by the reaction of the compound of formula III with the compound of formula X-A-X' (X and X' are halogen) in the presence of sodium iodide, etc., using a dehydrohalogenating agent (e.g. NaOH) at 50W150°C.
COPYRIGHT: (C)1981,JPO&Japio
JP2570880A 1980-02-29 1980-03-01 Tetrazole derivative Granted JPS56122365A (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
JP2570880A JPS56122365A (en) 1980-03-01 1980-03-01 Tetrazole derivative
FI810571A FI73423C (en) 1980-02-29 1981-02-24 FRAMEWORK FOR THE FRAMEWORK OF PHARMACOLOGICAL VEHICLES TETRAZOLDERIVAT.
AT81101352T ATE11047T1 (en) 1980-02-29 1981-02-25 TETRAZOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND ANTI-ULCER COMPOSITION CONTAINING THEM.
EP81101352A EP0035228B1 (en) 1980-02-29 1981-02-25 Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same
AU67638/81A AU537266B2 (en) 1980-02-29 1981-02-25 Tetrazole derivatives
PT72569A PT72569B (en) 1980-02-29 1981-02-25 Tetrazole derivatives process for the preparation thereof and anti-ulcer composition
DE8181101352T DE3167997D1 (en) 1980-02-29 1981-02-25 Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same
DK088081A DK162524C (en) 1980-02-29 1981-02-26 ANALOGY PROCEDURE FOR THE PREPARATION OF 5-ALKYLTHIO-TETRAZOLD DERIVATIVES
ES499930A ES8300723A1 (en) 1980-02-29 1981-02-27 1,5-Di:substd. tetrazole derivs. - useful as antiulcer agents
PH25282A PH17406A (en) 1980-02-29 1981-02-27 Tetrazole derivatives and anti-ulcer composition containing the same
CA000372021A CA1162196A (en) 1980-02-29 1981-02-27 Tetrazole derivatives having prophylactic and therapeutic activities against peptic and duodenal ulcers
US06/239,044 US4372953A (en) 1980-02-29 1981-02-27 Tetrazole derivatives, and anti-ulcer composition containing the same
MX815964A MX157430A (en) 1980-02-29 1981-02-27 PROCEDURE FOR THE PREPARATION OF TETRAZOLE DERIVATIVES
NO810675A NO166320C (en) 1980-02-29 1981-02-27 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAZOLD DERIVATIVES.
SU813252652A SU1212324A3 (en) 1980-03-01 1981-02-27 Method of producing tetrazole derivatives or their pharmaceutically acceptable acid-additive salts
ES510404A ES510404A0 (en) 1980-02-29 1982-03-12 A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE.
ES510403A ES510403A0 (en) 1980-02-29 1982-03-12 A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE.
ES510405A ES510405A0 (en) 1980-02-29 1982-03-12 "A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE".
ES520699A ES520699A0 (en) 1980-02-29 1983-03-16 A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE.
ES520898A ES8405383A1 (en) 1980-02-29 1983-03-23 1,5-Di:substd. tetrazole derivs. - useful as antiulcer agents
ES83520900A ES520900A0 (en) 1980-02-29 1983-03-23 A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE.
ES520899A ES520899A0 (en) 1980-02-29 1983-03-23 A PROCEDURE FOR THE PREPARATION OF A TETRAZOLE DERIVATIVE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2570880A JPS56122365A (en) 1980-03-01 1980-03-01 Tetrazole derivative

Publications (2)

Publication Number Publication Date
JPS56122365A true JPS56122365A (en) 1981-09-25
JPH0128022B2 JPH0128022B2 (en) 1989-05-31

Family

ID=12173279

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2570880A Granted JPS56122365A (en) 1980-02-29 1980-03-01 Tetrazole derivative

Country Status (1)

Country Link
JP (1) JPS56122365A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5759877A (en) * 1980-09-30 1982-04-10 Otsuka Pharmaceut Co Ltd Tetrazole derivative

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5759877A (en) * 1980-09-30 1982-04-10 Otsuka Pharmaceut Co Ltd Tetrazole derivative
JPH023786B2 (en) * 1980-09-30 1990-01-24 Otsuka Pharma Co Ltd

Also Published As

Publication number Publication date
JPH0128022B2 (en) 1989-05-31

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