JPS56108798A - Purification of erythropoietin - Google Patents
Purification of erythropoietinInfo
- Publication number
- JPS56108798A JPS56108798A JP1168580A JP1168580A JPS56108798A JP S56108798 A JPS56108798 A JP S56108798A JP 1168580 A JP1168580 A JP 1168580A JP 1168580 A JP1168580 A JP 1168580A JP S56108798 A JPS56108798 A JP S56108798A
- Authority
- JP
- Japan
- Prior art keywords
- erythropoietin
- antibody
- immobilized
- animal
- containing solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: To separate and purify erythropoietin which is an essential factor for the differentiation of erythrocyte cell, easily and in high purity, by the selective adsorption of an erythropoietin-containing solution with immobilized erythropoietin antibody, followed by the eluation of the adsorbed compound.
CONSTITUTION: An erythropoietin-containing solution (e.g. urine, plasma, etc.) is brought into contact with an immobilized erythropoietin antibody to effect the selective adsorption of erythropoietin taking advantage of the cross-reactivity of other kinds of erythropoietin. The adsorbed erythropoietin is isolated by elution. The immobilized erythropoietin anitbody can be prepared by carrying an erythropoietin antibody to a proper immobilization carrier, and making insoluble in water. The erythropoietin antibody is obtained, e.g. by administering erythropoietin as an immunogen to a proper animal, immunizing the animal by inoculation, and separating and purifying from the antiserum of the animal.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1168580A JPS56108798A (en) | 1980-02-01 | 1980-02-01 | Purification of erythropoietin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1168580A JPS56108798A (en) | 1980-02-01 | 1980-02-01 | Purification of erythropoietin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56108798A true JPS56108798A (en) | 1981-08-28 |
Family
ID=11784862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1168580A Pending JPS56108798A (en) | 1980-02-01 | 1980-02-01 | Purification of erythropoietin |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56108798A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8193415B2 (en) | 1999-10-26 | 2012-06-05 | Stichting Dienst Landbouwkundig Onderzock | Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase |
| US8309795B2 (en) | 2001-01-19 | 2012-11-13 | Phyton Holdings, Llc | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| US8492613B2 (en) | 2002-03-19 | 2013-07-23 | Stichting Dienst Landbouwkundig Onderzoek | GNTIII expression in plants |
| US8853370B2 (en) | 1998-12-09 | 2014-10-07 | Phyton Holdings, Llc | Plant-produced glycoprotein comprising human-type sugar chain |
| US8927810B2 (en) | 2002-03-19 | 2015-01-06 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
| US9745594B2 (en) | 2007-04-17 | 2017-08-29 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian-type glycosylation in plants by expression of a zebrafish glycosyltransferase |
-
1980
- 1980-02-01 JP JP1168580A patent/JPS56108798A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8853370B2 (en) | 1998-12-09 | 2014-10-07 | Phyton Holdings, Llc | Plant-produced glycoprotein comprising human-type sugar chain |
| US8193415B2 (en) | 1999-10-26 | 2012-06-05 | Stichting Dienst Landbouwkundig Onderzock | Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase |
| US8907163B2 (en) | 1999-10-26 | 2014-12-09 | Stichting Dienst Landbouwkundig Onderzoek | Transgenic plants expressing galactosyltransferase and sialyl transferase |
| US8309795B2 (en) | 2001-01-19 | 2012-11-13 | Phyton Holdings, Llc | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| US8735656B2 (en) | 2001-01-19 | 2014-05-27 | Phyton Holdings, Llc | Method of expressing galactosyltransferase and inhibiting xylosyltransferase or fucosyltransferase in a transgenic plant cell for secretory production of glycoproteins having human-type sugar chains |
| US9574218B2 (en) | 2001-01-19 | 2017-02-21 | Phyton Holdings, Llc | Method of co-expressing galactosyltransferase and a glycoprotein in a transgenic plant cell and sialylating the glycoprotein for production of glycoprotein having human-type sugar chain |
| US8492613B2 (en) | 2002-03-19 | 2013-07-23 | Stichting Dienst Landbouwkundig Onderzoek | GNTIII expression in plants |
| US8927810B2 (en) | 2002-03-19 | 2015-01-06 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
| US9255277B2 (en) | 2002-03-19 | 2016-02-09 | Stichting Dienst Landbouwkundig Onderzoek | GNTIII expression in plants |
| US9745594B2 (en) | 2007-04-17 | 2017-08-29 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian-type glycosylation in plants by expression of a zebrafish glycosyltransferase |
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