JPS5592363A - New 2-azetidinone derivative - Google Patents
New 2-azetidinone derivativeInfo
- Publication number
- JPS5592363A JPS5592363A JP16542778A JP16542778A JPS5592363A JP S5592363 A JPS5592363 A JP S5592363A JP 16542778 A JP16542778 A JP 16542778A JP 16542778 A JP16542778 A JP 16542778A JP S5592363 A JPS5592363 A JP S5592363A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- new
- derivative
- azetidinone derivative
- acylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:2-Azetidione derivative of formula I [R1 H or acylamino; X is S or methylene; R2 is formula -ACOOR4 (A is alkylene; R4 is H or ester residue) or tetrazolyl; R3 is H or formula II (R5 is H or lower alkyl; R6 is H, lower alkyl, aryl, etc.); provided that R3 is H when R1 is acylamino and that R2 is tetrazolyl when X is S and both R1 and R3 are H] or its salt.
EXAMPLE: 1-Carboxymethyl-4-carbboxymethylthio-2-azetidinone.
USE: β-Lactamase inhibitor.
PROCESS: A compound of formula V (R7 is ester residue) is obtained by the reaction of, e.g. a compound of formula III and a derivative of α-ketocarboxylic acid of formula IV.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16542778A JPS5592363A (en) | 1978-12-29 | 1978-12-29 | New 2-azetidinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16542778A JPS5592363A (en) | 1978-12-29 | 1978-12-29 | New 2-azetidinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5592363A true JPS5592363A (en) | 1980-07-12 |
Family
ID=15812210
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16542778A Pending JPS5592363A (en) | 1978-12-29 | 1978-12-29 | New 2-azetidinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5592363A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6023363A (en) * | 1983-02-02 | 1985-02-05 | ユニバーシティ・オブ・ノートル・ダム・ドゥ・ラク | N-(substituted methyl)-azetidin-2-ones |
WO1996035122A1 (en) * | 1995-05-03 | 1996-11-07 | Eli Lilly And Company | Combinatorial process for synthesizing azetidinone analogs |
-
1978
- 1978-12-29 JP JP16542778A patent/JPS5592363A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6023363A (en) * | 1983-02-02 | 1985-02-05 | ユニバーシティ・オブ・ノートル・ダム・ドゥ・ラク | N-(substituted methyl)-azetidin-2-ones |
WO1996035122A1 (en) * | 1995-05-03 | 1996-11-07 | Eli Lilly And Company | Combinatorial process for synthesizing azetidinone analogs |
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