JPS5572110A - Transfusion fluid for oxygen transfer - Google Patents

Transfusion fluid for oxygen transfer

Info

Publication number
JPS5572110A
JPS5572110A JP14505478A JP14505478A JPS5572110A JP S5572110 A JPS5572110 A JP S5572110A JP 14505478 A JP14505478 A JP 14505478A JP 14505478 A JP14505478 A JP 14505478A JP S5572110 A JPS5572110 A JP S5572110A
Authority
JP
Japan
Prior art keywords
component
oxygen transfer
perfluorocarbon
perfluoroadamantane
transfusion fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14505478A
Other languages
Japanese (ja)
Other versions
JPS6033367B2 (en
Inventor
Kazumasa Yokoyama
Koichi Yamauchi
Ryoichi Naito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Priority to JP14505478A priority Critical patent/JPS6033367B2/en
Publication of JPS5572110A publication Critical patent/JPS5572110A/en
Publication of JPS6033367B2 publication Critical patent/JPS6033367B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To provide a transfusion fluid for oxygen transfer, stable in the circulating blood, miscible with plasma diluent without disintegrating the emulsified particles, and composed of a perfluorocarbon compound, a perfluoroadamantane, etc.
CONSTITUTION: An oxygen-transferring emulsion having particle diameters of 0.05W0.3μ, and composed of (A) a 9W11C perfluorocarbon compound such as perfluorodecalin, and (B) (a) a 10W14C perfluorocarbon such as perfluoroadamantane, (b) a polymeric nonionic surface active agent having a molecular weight of about 2,000W20,000, (c) a phospholipide, (d) an 8W22C fatty acid, its salt or its monoglyceride, and (e) a medium, wherein the weight ratio of the (A) component to the (B) component is 95W50 to 5W50. Similary high effectivity to the preparation wherein the (B) component is perfluoro-t-alkylamine, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP14505478A 1978-11-24 1978-11-24 oxygen delivery infusion Expired JPS6033367B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14505478A JPS6033367B2 (en) 1978-11-24 1978-11-24 oxygen delivery infusion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14505478A JPS6033367B2 (en) 1978-11-24 1978-11-24 oxygen delivery infusion

Publications (2)

Publication Number Publication Date
JPS5572110A true JPS5572110A (en) 1980-05-30
JPS6033367B2 JPS6033367B2 (en) 1985-08-02

Family

ID=15376306

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14505478A Expired JPS6033367B2 (en) 1978-11-24 1978-11-24 oxygen delivery infusion

Country Status (1)

Country Link
JP (1) JPS6033367B2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080716A2 (en) * 1981-11-27 1983-06-08 Green Cross Corporation Perfluoro compound and emulsion thereof
JPS59501665A (en) * 1982-08-17 1984-10-04 サン　テツク　インコ−ポレ−テツド Perfluorocarbon emulsions, their preparation and use in therapy
US4530936A (en) * 1983-07-08 1985-07-23 Farmacon Research Corporation Composition and method for inhibiting the absorption of nutritional elements from the upper intestinal tract
JPS61242632A (en) * 1985-02-26 1986-10-28 アイ．エス．シ−．ケミカルズ　リミテツド Oil in water type emulsion of perfluorinated hydrocarbon andits stabilization
AU710142B2 (en) * 1993-03-16 1999-09-16 Alliance Pharmaceutical Corporation Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
WO2005023218A1 (en) * 2003-09-04 2005-03-17 Krist Co., Ltd. Emulsion of perfluororganic combination with a function of gastransport
US7417118B2 (en) 2003-04-08 2008-08-26 Nipro Corporation Pharmaceutical composition containing artificial oxygen carrier

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080716A2 (en) * 1981-11-27 1983-06-08 Green Cross Corporation Perfluoro compound and emulsion thereof
JPS59501665A (en) * 1982-08-17 1984-10-04 サン　テツク　インコ−ポレ−テツド Perfluorocarbon emulsions, their preparation and use in therapy
US4530936A (en) * 1983-07-08 1985-07-23 Farmacon Research Corporation Composition and method for inhibiting the absorption of nutritional elements from the upper intestinal tract
JPS61242632A (en) * 1985-02-26 1986-10-28 アイ．エス．シ−．ケミカルズ　リミテツド Oil in water type emulsion of perfluorinated hydrocarbon andits stabilization
AU710142B2 (en) * 1993-03-16 1999-09-16 Alliance Pharmaceutical Corporation Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
US7417118B2 (en) 2003-04-08 2008-08-26 Nipro Corporation Pharmaceutical composition containing artificial oxygen carrier
WO2005023218A1 (en) * 2003-09-04 2005-03-17 Krist Co., Ltd. Emulsion of perfluororganic combination with a function of gastransport

Also Published As

Publication number Publication date
JPS6033367B2 (en) 1985-08-02

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