JPS5559173A - Novel fluorouracil derivative - Google Patents
Novel fluorouracil derivativeInfo
- Publication number
- JPS5559173A JPS5559173A JP13148078A JP13148078A JPS5559173A JP S5559173 A JPS5559173 A JP S5559173A JP 13148078 A JP13148078 A JP 13148078A JP 13148078 A JP13148078 A JP 13148078A JP S5559173 A JPS5559173 A JP S5559173A
- Authority
- JP
- Japan
- Prior art keywords
- fluorouracil
- novel
- formylbenzene
- derivative
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A 5-fluorouracil derivative of the formula (Y is SO3, CO2, or SO2).
EXAMPLE: A 5-fluorouracil-m-formylbenzene-sulfonate.
USE: Decomposable into each component in vivo, and with both the physiolgical in actions of 5-fluorouracil and benzaldehyde or its devivative, particularly a carcinostatic. Administrable orally and easily preparable.
PROCESS: 5-Fluorouracil is dissolved in a slightly polar solvent, e.g. benzene, toluene, cyclohexane, or dichloroethane, and reacted with sulfonic, corboxylic or sulfinic acid derivative of formylbenzene to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13148078A JPS5559173A (en) | 1978-10-27 | 1978-10-27 | Novel fluorouracil derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13148078A JPS5559173A (en) | 1978-10-27 | 1978-10-27 | Novel fluorouracil derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5559173A true JPS5559173A (en) | 1980-05-02 |
Family
ID=15058951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13148078A Pending JPS5559173A (en) | 1978-10-27 | 1978-10-27 | Novel fluorouracil derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5559173A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2075014A2 (en) | 2002-05-24 | 2009-07-01 | Angiotech International Ag | Compositions and methods for coating medical implants |
| EP2181704A2 (en) | 2002-12-30 | 2010-05-05 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| WO2015089268A1 (en) | 2013-12-11 | 2015-06-18 | University Of Massachusetts | Compositions and methods for treating disease using salmonella t3ss effector protein (sipa) |
| KR20190083699A (en) | 2018-01-05 | 2019-07-15 | 가부시키가이샤 아우레오 | Composition for promoting thrombospondin 1 gene expression |
-
1978
- 1978-10-27 JP JP13148078A patent/JPS5559173A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2075014A2 (en) | 2002-05-24 | 2009-07-01 | Angiotech International Ag | Compositions and methods for coating medical implants |
| EP2181704A2 (en) | 2002-12-30 | 2010-05-05 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| WO2015089268A1 (en) | 2013-12-11 | 2015-06-18 | University Of Massachusetts | Compositions and methods for treating disease using salmonella t3ss effector protein (sipa) |
| US10201589B2 (en) | 2013-12-11 | 2019-02-12 | University Of Massachusetts | Compositions and methods for treating disease using Salmonella T3SS effector protein (SipA) |
| US10835575B2 (en) | 2013-12-11 | 2020-11-17 | University Of Massachusetts | Compositions and methods for treating disease using Salmonella T3SS effector protein (SipA) |
| EP3779446A1 (en) | 2013-12-11 | 2021-02-17 | University of Massachusetts | Compositions and methods for treating disease using salmonella t3ss effector protein (sipa) |
| KR20190083699A (en) | 2018-01-05 | 2019-07-15 | 가부시키가이샤 아우레오 | Composition for promoting thrombospondin 1 gene expression |
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