JPS55149213A - Remedy of dna for viral disease - Google Patents

Remedy of dna for viral disease

Info

Publication number
JPS55149213A
JPS55149213A JP5117979A JP5117979A JPS55149213A JP S55149213 A JPS55149213 A JP S55149213A JP 5117979 A JP5117979 A JP 5117979A JP 5117979 A JP5117979 A JP 5117979A JP S55149213 A JPS55149213 A JP S55149213A
Authority
JP
Japan
Prior art keywords
ara
remedy
dna
viruses
arabinofuranosylthymine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5117979A
Other languages
Japanese (ja)
Other versions
JPS6118526B2 (en
Inventor
Haruhiko Machida
Minero Saneyoshi
Hiroshi Yoshino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP5117979A priority Critical patent/JPS55149213A/en
Publication of JPS55149213A publication Critical patent/JPS55149213A/en
Publication of JPS6118526B2 publication Critical patent/JPS6118526B2/ja
Granted legal-status Critical Current

Links

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: Titled remedy that contains Ara-TMP or its salts as the major effective component, thus showing no cytotoxin, inhibiting selectively only the growth of virus and having much higher solubility than that of Ara-T.
CONSTITUTION: Ara-TMP (chemical name: 1-β-D- arabinofuranosylthymine- 5'- mono-phosphate) or its pharmaceutically permissible salt is used as the major component to give a DNA remedy for viral diseases. Although it does not deactivate viruses directly, it inhibits the DNA synthesis in new-born viruses on the propagation. It shows the same effectiveness as that of Ara-T (chemical name: 1-β-D- arabinofuranosylthymine) and further has higher solubility then Ara-T. The dosage is 50W500mg/kg orally in diseases caused by Herpes viruses and it can be administered in 0.5W20w/v% concentration on injection or as dripping solution, ointment and cream.
COPYRIGHT: (C)1980,JPO&Japio
JP5117979A 1979-04-24 1979-04-24 Remedy of dna for viral disease Granted JPS55149213A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5117979A JPS55149213A (en) 1979-04-24 1979-04-24 Remedy of dna for viral disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5117979A JPS55149213A (en) 1979-04-24 1979-04-24 Remedy of dna for viral disease

Publications (2)

Publication Number Publication Date
JPS55149213A true JPS55149213A (en) 1980-11-20
JPS6118526B2 JPS6118526B2 (en) 1986-05-13

Family

ID=12879605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5117979A Granted JPS55149213A (en) 1979-04-24 1979-04-24 Remedy of dna for viral disease

Country Status (1)

Country Link
JP (1) JPS55149213A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001131A1 (en) * 1986-08-15 1988-02-25 Nelson Research And Development Company Compositions comprising 1-oxohydrocarbyl-substituted azacyclohexanes and their uses
US5073544A (en) * 1986-08-15 1991-12-17 Whitby, Inc. Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001131A1 (en) * 1986-08-15 1988-02-25 Nelson Research And Development Company Compositions comprising 1-oxohydrocarbyl-substituted azacyclohexanes and their uses
EP0280703A1 (en) * 1986-08-15 1988-09-07 Nelson Res & Dev Compositions comprising 1-acyl-substituted morpholines, thiomorpholines and piperazines and their uses.
US5073544A (en) * 1986-08-15 1991-12-17 Whitby, Inc. Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes
EP0280703B1 (en) * 1986-08-15 1993-12-29 WHITBY RESEARCH, Inc. Compositions comprising 1-acyl-substituted morpholines, thiomorpholines and piperazines and their uses

Also Published As

Publication number Publication date
JPS6118526B2 (en) 1986-05-13

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