JPS55149213A - Remedy of dna for viral disease - Google Patents
Remedy of dna for viral diseaseInfo
- Publication number
- JPS55149213A JPS55149213A JP5117979A JP5117979A JPS55149213A JP S55149213 A JPS55149213 A JP S55149213A JP 5117979 A JP5117979 A JP 5117979A JP 5117979 A JP5117979 A JP 5117979A JP S55149213 A JPS55149213 A JP S55149213A
- Authority
- JP
- Japan
- Prior art keywords
- ara
- remedy
- dna
- viruses
- arabinofuranosylthymine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: Titled remedy that contains Ara-TMP or its salts as the major effective component, thus showing no cytotoxin, inhibiting selectively only the growth of virus and having much higher solubility than that of Ara-T.
CONSTITUTION: Ara-TMP (chemical name: 1-β-D- arabinofuranosylthymine- 5'- mono-phosphate) or its pharmaceutically permissible salt is used as the major component to give a DNA remedy for viral diseases. Although it does not deactivate viruses directly, it inhibits the DNA synthesis in new-born viruses on the propagation. It shows the same effectiveness as that of Ara-T (chemical name: 1-β-D- arabinofuranosylthymine) and further has higher solubility then Ara-T. The dosage is 50W500mg/kg orally in diseases caused by Herpes viruses and it can be administered in 0.5W20w/v% concentration on injection or as dripping solution, ointment and cream.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5117979A JPS55149213A (en) | 1979-04-24 | 1979-04-24 | Remedy of dna for viral disease |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5117979A JPS55149213A (en) | 1979-04-24 | 1979-04-24 | Remedy of dna for viral disease |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55149213A true JPS55149213A (en) | 1980-11-20 |
JPS6118526B2 JPS6118526B2 (en) | 1986-05-13 |
Family
ID=12879605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5117979A Granted JPS55149213A (en) | 1979-04-24 | 1979-04-24 | Remedy of dna for viral disease |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55149213A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988001131A1 (en) * | 1986-08-15 | 1988-02-25 | Nelson Research And Development Company | Compositions comprising 1-oxohydrocarbyl-substituted azacyclohexanes and their uses |
US5073544A (en) * | 1986-08-15 | 1991-12-17 | Whitby, Inc. | Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes |
-
1979
- 1979-04-24 JP JP5117979A patent/JPS55149213A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988001131A1 (en) * | 1986-08-15 | 1988-02-25 | Nelson Research And Development Company | Compositions comprising 1-oxohydrocarbyl-substituted azacyclohexanes and their uses |
EP0280703A1 (en) * | 1986-08-15 | 1988-09-07 | Nelson Res & Dev | Compositions comprising 1-acyl-substituted morpholines, thiomorpholines and piperazines and their uses. |
US5073544A (en) * | 1986-08-15 | 1991-12-17 | Whitby, Inc. | Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes |
EP0280703B1 (en) * | 1986-08-15 | 1993-12-29 | WHITBY RESEARCH, Inc. | Compositions comprising 1-acyl-substituted morpholines, thiomorpholines and piperazines and their uses |
Also Published As
Publication number | Publication date |
---|---|
JPS6118526B2 (en) | 1986-05-13 |
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