JPS5467023A - Stabilization of medicine - Google Patents

Stabilization of medicine

Info

Publication number
JPS5467023A
JPS5467023A JP13244477A JP13244477A JPS5467023A JP S5467023 A JPS5467023 A JP S5467023A JP 13244477 A JP13244477 A JP 13244477A JP 13244477 A JP13244477 A JP 13244477A JP S5467023 A JPS5467023 A JP S5467023A
Authority
JP
Japan
Prior art keywords
sodium salt
antibiotic
carboxylic acid
magnesium stearate
organic carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13244477A
Other languages
Japanese (ja)
Other versions
JPS56404B2 (en
Inventor
Iwanori Sugiura
Kazuo Sugito
Toshiaki Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to JP13244477A priority Critical patent/JPS5467023A/en
Publication of JPS5467023A publication Critical patent/JPS5467023A/en
Publication of JPS56404B2 publication Critical patent/JPS56404B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To prevent the lowering of titer of an antibiotic containing ampicillin and dicloxacilline and having synergistic effect, by adding a specific organic carboxylic acid sodium salt and magnesium stearate.
CONSTITUTION: An antibiotic composition containing ampicillin and dicloxacilline sodium salt (usually 1:1/3-2) is incorporated with an organic carboxylic acid sodium salt and magnesium stearate to prevent the moisture absorption, discoloration, and lowering of titer during storage. The organic carboxylic acid sodium salt is selected from sodium citrate, sodium succinate and sodium arginate, and its amount is 1/25- 1/5 of the sum of the antibiotic components; and the amount of magnesium stearate is 1/25-1/10 of the sum of the antibiotic components.
COPYRIGHT: (C)1979,JPO&Japio
JP13244477A 1977-11-07 1977-11-07 Stabilization of medicine Granted JPS5467023A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13244477A JPS5467023A (en) 1977-11-07 1977-11-07 Stabilization of medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13244477A JPS5467023A (en) 1977-11-07 1977-11-07 Stabilization of medicine

Publications (2)

Publication Number Publication Date
JPS5467023A true JPS5467023A (en) 1979-05-30
JPS56404B2 JPS56404B2 (en) 1981-01-08

Family

ID=15081500

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13244477A Granted JPS5467023A (en) 1977-11-07 1977-11-07 Stabilization of medicine

Country Status (1)

Country Link
JP (1) JPS5467023A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002529498A (en) * 1998-11-13 2002-09-10 ヤゴ・リサーチ・アクチェンゲゼルシャフト Dry powder for inhalation
WO2002034293A3 (en) * 2000-10-23 2003-03-13 Shanbrom Tech Llc Use of citric acid as antimicrobial agent or enhancer or as anticancer agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002529498A (en) * 1998-11-13 2002-09-10 ヤゴ・リサーチ・アクチェンゲゼルシャフト Dry powder for inhalation
JP2011231124A (en) * 1998-11-13 2011-11-17 Jagotec Ag Dry powder for inhalation
WO2002034293A3 (en) * 2000-10-23 2003-03-13 Shanbrom Tech Llc Use of citric acid as antimicrobial agent or enhancer or as anticancer agent

Also Published As

Publication number Publication date
JPS56404B2 (en) 1981-01-08

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