JPS54119021A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS54119021A JPS54119021A JP2512578A JP2512578A JPS54119021A JP S54119021 A JPS54119021 A JP S54119021A JP 2512578 A JP2512578 A JP 2512578A JP 2512578 A JP2512578 A JP 2512578A JP S54119021 A JPS54119021 A JP S54119021A
- Authority
- JP
- Japan
- Prior art keywords
- water
- mixed
- insoluble
- dissolving
- organic solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: To prepare a carcinostatic agent having slow and controlled releaseability suitable to the functions and the states of the applied position, by coating a core with a coating composition composed of a water-insoluble and water-permeable film- forming polymer and a higher fatty acid.
CONSTITUTION: A carcinostatic substance is mixed with a diluent, and if inecessary further mixed with a solution of a binder prepared by dissolving a binder and a plasticizer in an organic solvent. The mixture is thoroughly kneaded, granulated, and dried. The granules are mixed with a lubricant such as talc, and tabletted. The tablet thus obtained is coated with a coating liquid prepared by dissolving a water-insoluble and water-permeable film-forming polymer (e.g. methacrylic acid/ methacrylate copolymer, etc.) and a higher fatty acid in an organic solvent.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2512578A JPS54119021A (en) | 1978-03-06 | 1978-03-06 | Carcinostatic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2512578A JPS54119021A (en) | 1978-03-06 | 1978-03-06 | Carcinostatic agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54119021A true JPS54119021A (en) | 1979-09-14 |
Family
ID=12157216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2512578A Pending JPS54119021A (en) | 1978-03-06 | 1978-03-06 | Carcinostatic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54119021A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4462982A (en) * | 1981-10-05 | 1984-07-31 | Tanabe Seiyaku Co., Ltd. | Microcapsules and method of preparing same |
EP0861659A1 (en) * | 1991-02-21 | 1998-09-02 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
JP2002528408A (en) * | 1998-10-23 | 2002-09-03 | ファイザー・インク | Controlled release pharmaceutical formulation containing cGMPPDE-5 inhibitor |
JP2011098965A (en) * | 2009-11-09 | 2011-05-19 | Wyeth Llc | Coated drug spheroid for eliminating or alleviating conditions of vomiting, diarrhea or the like, and application thereof |
-
1978
- 1978-03-06 JP JP2512578A patent/JPS54119021A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4462982A (en) * | 1981-10-05 | 1984-07-31 | Tanabe Seiyaku Co., Ltd. | Microcapsules and method of preparing same |
EP0861659A1 (en) * | 1991-02-21 | 1998-09-02 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
JP2002528408A (en) * | 1998-10-23 | 2002-09-03 | ファイザー・インク | Controlled release pharmaceutical formulation containing cGMPPDE-5 inhibitor |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
JP2011098965A (en) * | 2009-11-09 | 2011-05-19 | Wyeth Llc | Coated drug spheroid for eliminating or alleviating conditions of vomiting, diarrhea or the like, and application thereof |
JP2015078240A (en) * | 2009-11-09 | 2015-04-23 | ワイス・エルエルシー | Coated drug spheroid for eliminating or alleviating conditions of vomiting, diarrhea or the like, and application of the same |
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