JPS51126281A - Cytootoxic substance - Google Patents
Cytootoxic substanceInfo
- Publication number
- JPS51126281A JPS51126281A JP51010786A JP1078676A JPS51126281A JP S51126281 A JPS51126281 A JP S51126281A JP 51010786 A JP51010786 A JP 51010786A JP 1078676 A JP1078676 A JP 1078676A JP S51126281 A JPS51126281 A JP S51126281A
- Authority
- JP
- Japan
- Prior art keywords
- cytootoxic
- substance
- cytootoxic substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4695/75A GB1496011A (en) | 1974-11-22 | 1975-02-04 | Defoaming composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS51126281A true JPS51126281A (en) | 1976-11-04 |
Family
ID=9782062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51010786A Pending JPS51126281A (en) | 1975-02-04 | 1976-02-03 | Cytootoxic substance |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS51126281A (en) |
BE (1) | BE838273A (en) |
DK (1) | DK43676A (en) |
NL (1) | NL7601132A (en) |
SE (1) | SE7601125L (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57143326A (en) * | 1981-03-03 | 1982-09-04 | Teijin Ltd | Polymer linked to cellular toxic substance and its preparation |
JPS57197295A (en) * | 1981-05-08 | 1982-12-03 | Erba Carlo Spa | Manufacture of daunorubicin-protein composite body |
JPS60172935A (en) * | 1984-02-16 | 1985-09-06 | Green Cross Corp:The | Preparation of composite material of substance having carcinostatic action |
JPS611622A (en) * | 1984-06-14 | 1986-01-07 | Teijin Ltd | Cytotoxic complex and preparation thereof |
WO1987004171A1 (en) * | 1985-12-27 | 1987-07-16 | Teijin Limited | Process for preparing antibody complex |
WO1988001513A1 (en) * | 1986-08-28 | 1988-03-10 | Teijin Limited | Cytocidal antibody complex and process for its preparation |
JPH03287545A (en) * | 1990-03-31 | 1991-12-18 | Res Dev Corp Of Japan | Target-directing polymeric drug compound and intermediate thereof |
JPH0662438B1 (en) * | 1986-08-28 | 1994-08-17 | Teijin Ltd | |
JPH0688913B2 (en) * | 1988-08-19 | 1994-11-09 | タノックス・バイオシステムズ・インコーポレーテッド | Molecular conjugate containing cell membrane blending agent |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2586564B1 (en) * | 1985-09-04 | 1989-04-07 | Pierre Tran Ba Loc | IMMUNOSUPPRESSIVE COMPOUNDS AND PROCESS FOR THEIR PREPARATION |
-
1976
- 1976-02-03 SE SE7601125A patent/SE7601125L/en not_active Application Discontinuation
- 1976-02-03 DK DK43676*#A patent/DK43676A/en not_active Application Discontinuation
- 1976-02-03 JP JP51010786A patent/JPS51126281A/en active Pending
- 1976-02-04 NL NL7601132A patent/NL7601132A/en not_active Application Discontinuation
- 1976-02-04 BE BE164096A patent/BE838273A/en unknown
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57143326A (en) * | 1981-03-03 | 1982-09-04 | Teijin Ltd | Polymer linked to cellular toxic substance and its preparation |
JPS57197295A (en) * | 1981-05-08 | 1982-12-03 | Erba Carlo Spa | Manufacture of daunorubicin-protein composite body |
JPS60172935A (en) * | 1984-02-16 | 1985-09-06 | Green Cross Corp:The | Preparation of composite material of substance having carcinostatic action |
JPS611622A (en) * | 1984-06-14 | 1986-01-07 | Teijin Ltd | Cytotoxic complex and preparation thereof |
WO1987004171A1 (en) * | 1985-12-27 | 1987-07-16 | Teijin Limited | Process for preparing antibody complex |
WO1988001513A1 (en) * | 1986-08-28 | 1988-03-10 | Teijin Limited | Cytocidal antibody complex and process for its preparation |
JPH0662438B1 (en) * | 1986-08-28 | 1994-08-17 | Teijin Ltd | |
JPH0688913B2 (en) * | 1988-08-19 | 1994-11-09 | タノックス・バイオシステムズ・インコーポレーテッド | Molecular conjugate containing cell membrane blending agent |
JPH03287545A (en) * | 1990-03-31 | 1991-12-18 | Res Dev Corp Of Japan | Target-directing polymeric drug compound and intermediate thereof |
Also Published As
Publication number | Publication date |
---|---|
NL7601132A (en) | 1976-08-06 |
DK43676A (en) | 1976-08-05 |
BE838273A (en) | 1976-08-04 |
SE7601125L (en) | 1976-08-05 |
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