JPH10272181A - Syringe and syringe assembly - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a syringe and a syringe assembly that can easily and accurately manage a medical liquid while being operated easily and safely. SOLUTION: The syringe assembly 1 consists of a syringe 10 and a device 6 with a holder 60. The syringe 10 is provided with the body 2 of the syringe, in which a liquid medicine 100 is housed, a connection part 3 screwed down on the tip part of the body 2 of the syringe, a gasket 4 and a plunger 5. The connection part 3 has a cylindrical body 31 of the connection part, a partition plate 32 for dividing a space in the body 31 of the connection part and an elastic cock 33 allowed to be pierced by a needle tube of the holder 60. A thin breaking part 34 in which a V-shaped groove is formed almost over the entire circumference thereof is provided between the partition plate 32 and the elastic cock 33. The connection part 3 is broken at the thin breaking part 34 so as to be just connectable to the device 6.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a syringe and a syringe assembly.

[0002]

2. Description of the Related Art Narcotic preparations such as morphine are stored and managed in glass ampules due to the properties of the drug.

When a drug solution (injection solution) stored in such an ampoule is administered to a patient, the following is performed.
First, the neck of the ampoule is cut, and a drug solution is inhaled into a syringe with a metal needle and collected. Next, the collected drug solution is injected into an infusion bag, mixed with the infusion in the infusion bag, and administered to the patient together with the infusion. Or
The syringe can be set in a syringe pump, or a drug solution can be diluted and then filled in a balloon pump to be administered to a patient.

[0004] However, the operation of cutting the ampule and collecting the drug solution contained in the ampule with a syringe is time-consuming and requires careful operation so as not to puncture a finger or hand with a needle. is there.

[0005] In particular, when the drug solution contained in the ampoule is a drug preparation, spilling it during the operation requires complicated procedures, so that the operation must be performed more carefully.

[0006] In the case of an ampoule, the sterility cannot be maintained from the time when the ampule is cut. Therefore, in order to prevent contamination of the drug solution due to contamination of bacteria and foreign substances, the above operation is performed in a sterile room. There is a need to do.

[0007] As described above, when the medicinal solution is managed by the ampule, the operability when administering the medicinal solution to the patient is poor.

[0008] Conventionally, a chemical solution is used in addition to the ampoule described above.
It is stored and managed in vials.

When administering a drug solution contained in a vial to a patient, a syringe with a metal needle is used, and the needle is pierced through a rubber stopper of the vial to collect the drug solution.
Thereafter, the collected drug solution is administered to the patient in the same manner as described above.

However, as in the case of the ampoule, the operation of collecting the drug solution stored in the vial with a syringe is troublesome, and the operation must be performed carefully so as not to puncture a finger or hand with a needle. There are, in particular,
When the drug solution contained in the vial is a drug preparation, the above operation needs to be performed more carefully, resulting in poor operability.

In the case of a vial, the inside of the vial is aseptically held by a rubber stopper, but since the outer surface of the rubber stopper is not sterile, the needle of the syringe is connected to the rubber stopper. If coring occurs when penetrating the vial, bacteria and foreign substances on the outer surface of the rubber stopper enter the inside of the vial,
The chemicals may be contaminated by the bacteria and foreign substances.

In the case of a vial,
It is possible to tamper with the medicinal solution in the vial by collecting the medicinal solution from the vial or injecting liquid such as water or other medicinal solution into the vial, so it is necessary to strictly manage the medicinal solution. , Management is troublesome.

[0013]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a syringe and a syringe assembly which can be easily and safely operated, and can easily and reliably manage a chemical solution.

[0014]

This and other objects are achieved by the present invention which is defined below as (1) to (14).

(1) In a syringe having a syringe body, a gasket capable of sliding in a liquid-tight manner along the inner surface of the syringe body, and a plunger for moving the gasket in the axial direction, a tip end of the syringe body And a connecting portion connected to an instrument for taking out a liquid from the syringe body, and the connecting portion is configured to be connectable to the instrument only by being broken. Syringe.

(2) The syringe according to the above (1), wherein the connection portion has an elastic stopper capable of penetrating a needle tube.

(3) The syringe according to the above (2), wherein the connection portion has a needle stopping means for preventing a needle tube from puncturing before the connection portion is broken.

(4) The syringe according to the above (2) or (3), wherein the connecting portion has aseptic holding means for holding the outer surface of the elastic plug aseptically before breaking.

(5) The syringe according to any one of the above (2) to (4), wherein the connection portion has a partition plate arranged to face the elastic plug via a break portion.

(6) The connection according to any one of (1) to (5), wherein the connection portion is formed of a member separate from the syringe main body, and is configured to be fixed to the syringe main body by fitting. Syringe.

(7) The syringe according to the above (6), further comprising lock means for holding the fitted state when the fitting is completed.

(8) The plunger is configured so that the gasket can be moved only in a direction in which the volume of the space formed by the gasket and the syringe body decreases. The syringe according to any one of 7).

(9) The syringe according to any one of the above (1) to (8), wherein the syringe body has guide means for guiding the plunger.

(10) The syringe according to any one of the above (1) to (9), wherein the syringe body has detachment preventing means for preventing detachment of the gasket from the syringe body.

(11) The syringe according to any one of the above (1) to (9), wherein the gasket is provided with a puncture preventing means for preventing a needle tube from puncturing.

(12) The syringe according to any one of (1) to (11) above, and a device connected to the connection portion after the breakage for taking out a liquid from inside the syringe body. Syringe assembly.

(13) The syringe assembly according to the above (12), wherein the device has a holder provided with a needle tube communicating with the inside of the syringe body when the device is connected to the connection portion.

(14) The above-mentioned (12) having a connection state maintaining means for maintaining a state in which the device is connected to the connection portion.
Or the syringe assembly according to (13).

[0029]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a syringe and a syringe assembly according to the present invention will be described in detail with reference to the preferred embodiments shown in the accompanying drawings.

FIG. 1 is a perspective view showing a configuration example of a syringe assembly (after assembly) of the present invention, and FIG. 2 is a cross-sectional view showing a configuration example of a syringe assembly (before assembly) of the present invention.
For convenience of description, the upper side in FIG. 2 will be described as “distal end”, and the lower side will be described as “base end” or “rear end”.

As shown in these figures, the syringe assembly 1
Is composed of a syringe 10 and an instrument 6 for taking out a liquid (in the present embodiment, the drug solution 100) from a syringe body 2 described later of the syringe 10.

The syringe 10 has a syringe body 2, a connecting portion 3 connected to the instrument 6, a gasket 4, and a plunger 5.

The syringe body 2 is a cylindrical member, and is made of a rigid material having a predetermined rigidity.

The constituent material of the syringe body 2 is, for example, polypropylene, polyethylene, polystyrene, polyamide, polycarbonate, polyvinyl chloride, poly-
Various resins such as (4-methylpentene-1), acrylic resins, acrylonitrile-butadiene-styrene copolymers, polyesters such as polyethylene terephthalate, butadiene-styrene copolymers, and cyclic polyolefins may be mentioned. For example, resins such as polypropylene and cyclic polyolefin are preferred because they are easily heat-resistant. The constituent material of the syringe body 2 is preferably substantially transparent or translucent in order to secure the visibility inside.

The syringe body 2 may be made of a metal material such as stainless steel, titanium, aluminum or the like, or a ceramic material such as glass or alumina, in addition to the above materials.

FIG. 3 is a sectional view showing a distal end portion of the syringe body 2 and a proximal end portion of the connecting portion 3, and FIG. 4 is a sectional view taken along line AA in FIG.
It is sectional drawing in a line. For convenience of explanation, the upper side in FIG. 3 will be described as “distal end”, and the lower side will be described as “base end” or “rear end”.

As shown in these figures, the syringe body 2
A male screw 21 and a projection 22 are formed on the outer peripheral portion of the distal end portion. In this case, the projection 22 is located on the rear end side of the male screw 21.

As shown in FIG. 2, the connecting portion 3 is a member configured to be connectable to the instrument 6 only when broken, and is installed at the distal end of the syringe body 2.

The connecting portion 3 is a cylindrical connecting portion main body 31.
And a partition plate 32 for partitioning a space in the connection portion main body 31.
And an elastic plug 33 through which a needle tube 63 of a holder 60 described later can penetrate. Partition plate 32 and elastic plug 33
Are arranged inside the connection portion main body 31.

As the constituent material of the connecting portion main body 31, for example, polypropylene, polyethylene, polystyrene, polyamide, polycarbonate, polyvinyl chloride, poly-
Various resins such as (4-methylpentene-1), acrylic resins, acrylonitrile-butadiene-styrene copolymers, polyesters such as polyethylene terephthalate, butadiene-styrene copolymers, and cyclic polyolefins may be mentioned. Is easy,
Resins such as polypropylene and cyclic polyolefin are preferred.

As shown in FIG. 3, a female screw 311 to be screwed with the male screw 21 of the syringe main body 2 is formed on the inner peripheral portion of the base end of the connecting portion main body 31. The main body 31 and the syringe main body 2).
The connection part 3 is fixed to the syringe body 2.

As shown in FIGS. 3 and 4, an inner peripheral portion of the base end of the connecting portion main body 31 is provided with the syringe main body 2.
A projection 312 that engages with the projection 22 is formed. The protrusion 312 is located on the rear end side of the female screw 311.

When the male screw 21 of the syringe main body 2 and the female screw 311 of the connection part main body 31 are screwed together when assembling the syringe 10, as shown in FIG.
2 moves outward along the slope 221, climbs over the top 222, moves inward along the end face 223, and
Engage with. As a result, rotation of the male screw 21 and the female screw 311 in a direction in which the screw engagement is released is prevented, and the connection portion main body 3
1 and the syringe body 2 in a fitted state, that is, a female screw 3
The screwed state between the male screw 11 and the male screw 21 is maintained.

Therefore, the projections 312 and the projections 22
As a result, when the fitting between the connecting portion main body 31 and the syringe main body 2 is completed, that is, when the screwing between the female screw 311 and the male screw 21 is completed, the locking means for holding this screwed state (fitted state). Is configured.

In the syringe 10, as described above,
Since the connecting portion 3 is formed as a separate member from the syringe main body 2, assembly of the syringe 10 in consideration of sterilization can be easily performed.

Then, the projection 312 engages with the projection 22,
Thereby, the screwed state between the female screw 311 and the male screw 21 is maintained, so that an accident such as detachment of the connection portion 3 from the syringe body 2 can be prevented.

As shown in FIG. 3, the elastic plug 33 is disposed on the distal end side of the female screw 311 in a preferably airtight manner with respect to the connecting portion main body 31. After the connecting portion 3 is broken at the thin break portion 34 described below (after opening), the elastic plug 33 prevents contamination of the chemical solution 100 described below by bacteria and foreign matter.

Examples of the constituent material of the elastic plug 33 include various rubber materials (especially vulcanized) such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, and polyurethane. And various elastic materials such as polyester, polyester, polyamide, olefin, and styrene, and elastic materials such as mixtures thereof. Of these,
The tip of the needle tube 63 of the holder 60 to be described later can be easily pierced, coring hardly occurs, and after the needle tube 63 is pierced, the restoring property when the needle tube 63 is pulled out, that is, the needle tube 63 pierces. A hole having a good sealing property (self-closing property) is preferably used.

The connecting portion main body 31 has a stepped portion 35 formed therein, and the outer periphery of the elastic plug 33 has a stepped portion 35.
And the distal end surface 25 of the syringe main body 2 to be clamped and fixed.

As shown in FIG. 2, the partition plate 32 is provided on the distal end side of the elastic plug 33. As a constituent material of the partition plate 32, the same material as that of the connection portion main body 31 described above is used, and the partition plate 32 is preferably formed integrally with the connection portion main body 31.

The partition plate 32 is made of a material other than the above materials.
For example, it may be made of a metal material such as stainless steel, titanium, and aluminum, or a ceramic material such as glass and alumina.

The partition plate 32, together with the connecting portion main body 31 and the elastic plug 33, together with the closed space 38 surrounded by them.
To form

Before the connection portion 3 is broken (before opening), the closed space 38 is maintained in an aseptic state (aseptically), so that the front surface (outer surface) of the elastic plug 33 is aseptic. Is held. Before assembling, at least the inside may be sterilized by a method such as gamma sterilization, EOG sterilization, or autoclave sterilization to make it aseptic.

The partition plate 32 prevents the elastic plug 33 from being punctured by a needle tube or the like. Thus, before the connection portion 3 is broken, the medical solution 100 is collected from the inside of the syringe main body 2 from the distal end side, or a liquid such as water or another chemical solution is injected into the syringe main body 2 and the inside of the syringe main body 2 is removed. Falsification of the chemical solution 100 (hereinafter simply referred to as “falsification of the chemical solution 100”) can be prevented.

Between the partition plate 32 and the elastic plug 33 in the connecting portion main body 31, there is formed a thin break portion (break portion) 34 in which a V-shaped groove is formed over substantially the entire outer periphery thereof. Is provided. In other words, the partition plate 32 is disposed to face the elastic plug 33 via the thin-walled broken portion 34.

When the tip of the connecting portion 3 is twisted or bent, the connecting portion 3 is broken at the thin break portion 34. That is, the partition plate 32 is connected to the connecting portion main body 3 on the rear end side.
1 and the connection part 3 is opened.

As shown in FIG. 2, a gasket 4 which is slidable in a liquid-tight manner along the inner peripheral surface of the syringe body 2 is housed inside the syringe body 2.

The gasket 4 is made of, for example, natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-
Composed of various rubber materials such as butadiene rubber and silicone rubber (especially vulcanized), various elastomers such as polyurethane, polyester, polyamide, olefin, and styrene, and elastic materials such as mixtures thereof. This is a substantially columnar member to be formed.

The gasket 4 is not limited to the whole made of the above-mentioned material.
May be composed of the above materials.

On the outer peripheral surface of the gasket 4, a plurality of ring-shaped projections 41 are formed over the entire circumference. When the gasket 4 slides, the protruding portion 41 holds the syringe body 2.
And has a function to maintain good air-tightness and liquid-tightness and to maintain appropriate slidability.

At the rear end of the gasket 4, a disk-shaped protection plate 42 is provided. The protection plate 42 prevents puncture of a needle tube or the like. Thereby, the falsification of the chemical solution 100 from the rear end side can be prevented.

At the rear end of the protection plate 42, a circular concave portion 43 is formed to engage with the plunger 5 described later.

The syringe body 2 has a flange 23 at its base end and a cylindrical guide member 24 at the inner periphery of the base end.

The inner peripheral surface 241 of the guide member 24 guides the plunger 5 so that the plunger 5 described later can be stably moved in the axial direction.

The guide member 24 has a distal end surface 24.
2 prevents the gasket 4 from being detached from the syringe body 2 by making contact with the rear end surface 421 of the protection plate 42 described above.

Accordingly, the guide member 24 serves both as a guide means for guiding the plunger 5 and a detachment preventing means for preventing the gasket 4 from being detached.

The liquid medicine 100 is stored in advance in the interior of the syringe main body 2, that is, in a space partitioned by the gasket 4 and the elastic plug 33 in the syringe main body 2.

Specific examples of the drug solution 100 include vitamin preparations (multivitamin preparations), various amino acids, antithrombotic agents such as heparin, insulin, antibiotics, antitumor agents, analgesics, inotropic agents, intravenous anesthetics, Examples include antiparkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmic agents, correction electrolytes, and the like.

In particular, when the drug solution 100 is a drug preparation such as morphine, strict management is required so as not to be falsified.
The management can be performed easily and reliably.

The syringe body 2 is provided with a scale. With this scale, the amount of the drug solution 100 in the syringe main body 2 can be grasped.

The plunger 5 is a member for moving the gasket 4 in the axial direction.
A notch portion 51 that engages with the step portion 422 is formed, and a disk-shaped grip portion 52 is formed at the rear end portion.

In the plunger 5, a force is transmitted from the plunger 5 to the gasket 4 in a direction in which the plunger 5 is pressed, but a force is not transmitted from the plunger 5 to the gasket 4 in a direction in which the plunger 5 is pulled.

As a constituent material of the plunger 5, the same material as that of the syringe body 2 described above can be used.

As shown in FIG. 1, the instrument 6
0, a winged needle 7 and a tube 8 connecting these.

As shown in FIG. 2, the holder 60 is composed of a bottomed cylindrical holder body 61 to be fitted to the connecting portion main body 31 and a needle tube 63 installed concentrically with the holder body 61. Have.

As the constituent material of the holder main body 61, the same material as that of the syringe main body 2 described above can be mentioned, and it is preferable that the material is substantially transparent or translucent in order to secure the visibility of the inside.

The constituent material of the needle tube 63 is, for example, a metal material such as stainless steel, titanium, aluminum, an aluminum alloy, polycarbonate, polystyrene, poly- (4-methylpentene-1), acrylonitrile-butadiene- Relatively hard resin materials such as styrene copolymers and polyphenylene sulfide are exemplified.

The needle tube 63 is supported and fixed to one end of a support member (luer adapter 62) having a male thread. A female screw that is screwed with the male screw is formed at the tip of the holder main body 61, and the needle tube 63 is detachably mounted and fixed to the holder main body 61 by screwing these.

The other end of the luer adapter 62 is connected to one end of the tube 8 communicating with the needle tube 63. A winged needle 7 is connected to the other end of the tube 8.

Around the needle tube 63, an expandable (elastic material) enclosing member 64 for enclosing at least the distal end of the needle tube 63 is provided. In this case, the enclosing member 64
Is preferably fitted or adhered to the luer adapter 62. The encapsulating member 64 serves to prevent contamination of the needle tube 63 when not in use and after use,
3 serves to prevent liquid leakage.

As the enclosing member 63, for example, a member made of a film made of the same material as the gasket 4 described above and which can be easily penetrated by the tip of the needle tube 63 is preferably used.

The holder 60 of the device 6 is detachably connected to the connecting portion 3 after the connecting portion 3 is broken at the breaking portion 34. The length of the needle tube 63 of the holder 60 is such that when the holder 60 is connected to the connection portion 3,
The length is set such that the elastic plug 33 can be sufficiently penetrated and that the gasket 4 does not contact the gasket 4 when the gasket 4 is moved to the tip of the syringe body 2.

Next, the operation of the syringe 10 and the syringe assembly 1 will be described. FIG. 5 is a cross-sectional view showing the syringe 10 in a state where the connecting portion 3 is broken at the breaking portion 34, and FIG.
Holder 6 with holder 60 connected to connection portion 3
FIG. 7 is a sectional view showing the syringe assembly 1 in a state where the plunger 5 is inserted into the syringe main body 2. FIG. 8 is a sectional view showing the syringe assembly 1 in a state where the plunger 5 is inserted into the syringe main body 2. FIG. 2 is a cross-sectional view showing the syringe assembly 1 in a folded state. For convenience of description, the upper side in FIGS. 5 to 8 will be described as “distal end”, and the lower side will be described as “base end” or “rear end”, respectively.

First, as shown in FIG. 2, the distal end of the connecting portion 3 is bent by, for example, pressing in the lateral direction in FIG.
As shown in the figure, the connecting portion 3 is broken at the thin break portion 34. In addition, since the connection part 3 before break is long enough with respect to the holder 60, and since the partition plate 32 is provided, the instrument 6 cannot be connected to the connection part 3 before break.

Next, as shown in FIG. 6, the holder 60 of the device 6 is mounted on the broken connection portion 3.

That is, the holder body 6 of the holder 60
1 is arranged at the front end of the connection part main body 31 of the connection part 3, and then the holder main body 61 is pushed along the outer peripheral surface of the connection part main body 31 to the rear end of the connection part main body 31. At this time, the needle tube 63 penetrates the encapsulating member 64 and further penetrates the elastic plug 33, whereby the needle tube 63 communicates with the inside of the syringe body 2. At this time, the encapsulating member 64 is pressed by the elastic plug 33 and moved toward the distal end side, and is folded in a bellows shape. Further, the holder main body 61 and the connection portion main body 31 are fitted.
In this way, the device 6 is connected to the connection 3.

Next, as shown in FIG. 7, the plunger 5 is set at the rear end of the syringe main body 61. And
With the tip of the syringe 10 facing upward, the plunger 5 is
By performing a pressing operation in a direction (a tip side) in which the volume of the space formed by the gasket 4 and the syringe main body 2 decreases (primary side), priming, that is, in the syringe main body 2, the connection portion main body 3, the needle tube 63, the tube 8, and the needle tube 71 Of air.

Next, the needle tube 71 of the winged needle 7 shown in FIG. 1 is punctured into the blood vessel or subcutaneous of the patient, and is fixed with the wing 72.

Next, the plunger 5 is pressed toward the distal end to administer the drug solution 100 to the patient. In this case, the operation of the plunger 5 causes the gasket 4 to move to the distal end side.
And via the needle tube 71 of the winged needle 7 to the patient.

When the plunger 5 is operated, the plunger 5 is guided by the guide member 24, so that the plunger 5 is stabilized and the operation can be performed smoothly.

After the administration of the medicinal solution is completed, the winged needle 7
The needle tube 71 is withdrawn from the patient, and the plunger 5 is withdrawn from the syringe body 2 as shown in FIG.

When removing the plunger 5 from the syringe body 2, the gasket 4 does not move. That is,
In the syringe 10, the gasket 4 cannot be moved in the direction in which the volume of the space formed by the gasket 4 and the syringe body 2 increases (toward the rear end). For this reason, in the syringe 10, liquid such as water or another chemical solution cannot be sucked into the syringe main body 61 later.
The liquid medicine (residual liquid) remaining in the syringe main body 61 can be managed easily and reliably. Therefore, syringe 1
0 is particularly suitable for the management of drug formulations.

Next, the holder 60 is removed from the connection portion 3. In this case, when the needle tube 63 is removed from the elastic plug 33, the envelope member 64 that has been folded in a bellows shape is instantaneously restored to its original shape by its elastic force, and envelopes the needle tube 63. Thereby, for example, the needle tube 63 due to bacteria, foreign matter, or the like can be used.
Is prevented, and the liquid is prevented from leaking from the needle tube 63 and scattered around.

On the other hand, the elastic plug 33 is instantaneously restored to its original shape by its elastic force, and the inside of the syringe main body 61 is sealed by the elastic plug 33. This allows, for example,
The inside of the syringe main body 61 and the chemical solution 100 remaining in the syringe main body 61 are prevented from being contaminated by bacteria and foreign substances, and the leakage of the liquid from the syringe main body 61 is prevented.

Here, in the case of administering the drug solution contained in another syringe 10 subsequent to the administration of the drug solution,
As described above, the holder 60 is removed from the connection part 3, the connection part 3 of the other syringe 10 is broken, and the holder 60 is mounted on the broken part 3. During this operation (during replacement of the syringe 10), as described above, the encapsulation member 64 prevents contamination of the needle tube 63 and leakage of liquid from the needle tube 63, respectively.

Next, another configuration example of the instrument 6 will be described. FIG. 9 is a cross-sectional view illustrating another configuration example of the device 6. In addition,
The description of the common points with the instrument 6 shown in FIGS. 1 and 2 and the like will be omitted, and the main differences will be described.

As shown in the figure, the device 6 includes a holder 6
0 and the bottle needle 9 communicating with the needle tube 63. The bottle needle 9 is joined or integrated with the distal end side of the luer adapter 62. A hole 91 is formed at the tip of the bottle needle 9.

Such a device 6 is used, for example, when injecting the drug solution 100 into an infusion bag.

The instrument of the syringe assembly of the present invention, that is, the instrument connected to the broken connection portion is not limited to the instrument 6 shown in FIGS. 1 and 9 described above. Selected as appropriate.

As described above, according to the syringe 10 and the syringe assembly 1, when administering the drug solution 100 to a patient, the step of cutting the ampule and collecting the drug solution from the ampoule as in the case of using an ampoule. Also, unlike the case of using a vial bottle, there is no step of collecting the drug solution from the vial bottle, and the drug solution can be directly administered to the patient, or the drug solution can be directly injected into a container such as an infusion bag.

Therefore, the operation can be performed easily and quickly without spilling the chemical solution, and there is no risk of erroneous sticking by a metal needle or the like at the time of collecting the chemical solution, and the safety at the time of operation is improved. .

Since the closed space 38 of the connecting portion 3 and the surface of the elastic plug 33 are kept in a sterile state by the partition plate 32 until the connecting portion 3 is broken, the elastic plug 33 is pierced by the needle tube 63. This can prevent contamination of the chemical solution 100 due to contamination of bacteria and foreign matter when the cleaning is performed. For this reason, there is no need to operate in a sterile room, so that operability is good.

Further, the connection portion 3 cannot be used unless it is broken. If the connection portion 3 is once broken and used, the connection portion 3 does not return to the state before the breakage. Or used can be easily and accurately determined. For this reason, the chemical solution can be easily and reliably managed.

Further, since the plunger 5 and the gasket 4 can move the gasket 4 only to the front end side (since the gasket 4 cannot be moved to the rear end side), water or other gasket can be operated. The liquid such as the chemical liquid cannot be sucked into the syringe main body 61, thereby preventing the chemical liquid 100 from being falsified. For this reason,
The drug solution 100 can be easily and reliably managed, and is particularly suitable for a drug solution requiring strict management, such as a drug preparation such as morphine.

Next, another configuration example of the syringe assembly 1 will be described. FIGS. 10 and 11 show another example of the structure of the syringe assembly 1, respectively, in which the holder 60
FIG. 5 is a cross-sectional view showing the holder 60 and the connection portion 3 connected to the holder 60.

The description of common points with the syringe assembly 1 shown in FIGS. 1 and 2 and the like will be omitted, and the main differences will be described. In addition, for convenience of description, the upper side in FIGS. 10 and 11 will be described as “distal end”, and the lower side will be described as “base end” or “rear end”, respectively.

In the syringe assembly 1 shown in FIG. 10, a groove 313 is formed on the outer peripheral portion of the connecting portion main body 31 of the connecting portion 3. This groove 313 is formed along the circumferential direction of the connection portion main body 31. The inner peripheral portion of the holder main body 61 of the holder 60 has a ridge 6 engaging with the groove 313.
11 are formed.

The groove 313 and the ridge 611 engage when the holder 60 is mounted on the broken connection part 3, thereby preventing the holder 60 from being detached from the connection part 3. In particular, even when the restoring force of the contracted enclosing member 64 is applied, the holder 60 from the connecting portion 3 is opposed thereto.
Is prevented from coming off.

Therefore, the grooves 313 and the ridges 611
Thereby, the connection state maintaining means for maintaining the state where the appliance 6 is connected to the connection portion 3 is configured.

In the syringe assembly 1 shown in FIG. 11, a ridge 314 is formed on the outer periphery of the connecting portion main body 31 of the connecting portion 3. The protrusion 314 is formed along the circumferential direction of the connection portion main body 31. A groove 612 is formed on the inner peripheral portion of the holder main body 61 of the holder 60 to engage with the ridge 314.

The protrusions 314 and the grooves 612 are engaged when the holder 60 is mounted on the broken connection part 3, thereby preventing the holder 60 from being detached from the connection part 3. In particular, even when the restoring force of the contracted enclosing member 64 is applied, the holder 60 from the connecting portion 3 is opposed thereto.
Is prevented from coming off.

Therefore, these ridges 314 and grooves 612
Thereby, the connection state maintaining means for maintaining the state where the appliance 6 is connected to the connection portion 3 is configured.

As described above, the configurations of the syringe and the syringe assembly of the present invention have been described based on the illustrated configuration examples. However, the present invention is not limited to these, and the configuration of each part has the same function. Any configuration can be used.

For example, in the present invention, the syringe body and the connection portion may be joined by fusion or the like, or may be adhered by various adhesives or the like.

[0115]

As described above, according to the syringe and the syringe assembly of the present invention, the operation for administering the drug solution to the patient with a simple operation and in a short time, and the drug solution such as an infusion bag or the like can be used. An operation for injecting into a container can be performed, and the safety at the time of operation is high.

If the connecting portion is not broken, a device for removing liquid from the syringe body cannot be connected to the connecting portion and cannot be used. Therefore, the device is unused or used. It is possible to easily and accurately determine whether or not the drug solution is a drug solution, thereby easily and reliably managing a drug solution, particularly a drug preparation.

When the connecting portion has aseptic holding means for holding the outer surface of the elastic plug aseptically before breaking,
In particular, when the elastic plug has a partition plate that is disposed to face through the breaking portion, when the elastic plug is pierced with a needle tube,
It is possible to prevent contamination of the chemical solution due to contamination of bacteria and foreign substances. For this reason, there is no need to operate in a sterile room, so that operability is good.

Further, in the present invention, before the connection portion is broken or the like,
Chemical liquid can be prevented from being tampered with,
In particular, the drug preparation can be managed easily and reliably.

When the connecting portion is formed of a separate member from the syringe main body and is configured to be fixed to the syringe main body by fitting, it is possible to easily assemble the syringe in consideration of sterilization. .

In particular, when the fitting is completed, if there is a locking means for holding the fitted state, the connecting portion can be more securely attached to and fixed to the syringe body. Accidents such as detachment of the connection portion from the syringe body can be prevented.

Further, in the case where there is provided a connection state maintaining means for maintaining a state in which the device is connected to the connection portion, the detachment of the device from the connection portion can be prevented.

[Brief description of the drawings]

FIG. 1 is a perspective view showing a configuration example of a syringe assembly (after assembly) of the present invention.

FIG. 2 is a cross-sectional view showing a configuration example of a syringe assembly (before assembly) of the present invention.

FIG. 3 is a cross-sectional view showing a distal end portion of a syringe main body and a proximal end portion of a connection portion in the present invention.

FIG. 4 is a cross-sectional view taken along line AA in FIG.

FIG. 5 is a cross-sectional view showing the syringe according to the present invention in a state where a connection portion is broken at a break portion.

FIG. 6 is a cross-sectional view showing the holder and the connection part in a state where the holder according to the present invention is connected to the connection part.

FIG. 7 is a sectional view showing the syringe assembly in a state where the plunger according to the present invention is inserted into the syringe body.

FIG. 8 is a cross-sectional view showing the syringe assembly in a state where the plunger according to the present invention is pulled out of the syringe body.

FIG. 9 is a cross-sectional view showing another configuration example of the device according to the present invention.

FIG. 10 is a sectional view showing another configuration example of the syringe assembly of the present invention, showing the holder and the connection portion in a state where the holder is connected to the connection portion.

FIG. 11 is a cross-sectional view showing another configuration example of the syringe assembly of the present invention, showing the holder and the connection portion in a state where the holder is connected to the connection portion.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Syringe 10 Syringe assembly 2 Syringe main body 21 Male screw 22 Projection 221 Slope 222 Top 223 End surface 23 Flange 24 Guide member 241 Inner peripheral surface 242 Tip surface 25 Tip surface 3 Connection part 31 Connection part main body 311 Female screw 312 Projection 313 Groove 314 32 Partition plate 33 Elastic plug 34 Thin break portion 35 Stepped portion 38 Closed space 4 Gasket 41 Projection 42 Protective plate 421 Rear end surface 422 Stepped portion 43 Concave portion 5 Plunger 51 Notch portion 52 Gripping portion 6 Instrument 60 Holder 61 Holder body 611 Convex stripe 612 Groove 62 Luer adapter 63 Needle tube 64 Enclosure member 7 Needle with wing 71 Needle tube 72 Wing 8 Tube 9 Bottle needle 91 Hole 100 Chemical solution

Claims (14)

[Claims] 1. A syringe having a syringe body, a gasket capable of sliding in a liquid-tight manner along an inner surface of the syringe body, and a plunger for moving the gasket in an axial direction, wherein a tip end of the syringe body is provided. A syringe connected to an instrument for taking out a liquid from inside the syringe body, wherein the connection is configured to be connectable to the instrument only by being broken. . 2. The syringe according to claim 1, wherein the connection portion has an elastic stopper capable of penetrating a needle tube. 3. The syringe according to claim 2, wherein the connection portion has a needle stop means for preventing a needle tube from puncturing before the connection portion is broken. 4. The syringe according to claim 2, wherein the connecting portion has aseptic holding means for holding the outer surface of the elastic plug aseptically before breaking. 5. The syringe according to claim 2, wherein the connection portion has a partition plate facing the elastic plug via a break portion. 6. The syringe according to claim 1, wherein the connecting portion is formed as a separate member from the syringe main body, and is configured to be fixed to the syringe main body by fitting. 7. The syringe according to claim 6, further comprising lock means for maintaining the fitted state when the fitting is completed. 8. The gasket according to claim 1, wherein the plunger can move the gasket only in a direction in which a volume of a space formed by the gasket and the syringe body decreases. The syringe described in Crab. 9. The syringe according to claim 1, wherein the syringe body has guide means for guiding the plunger. 10. The syringe according to claim 1, wherein said syringe body has a separation preventing means for preventing separation of said gasket from said syringe body. 11. The syringe according to claim 1, wherein the gasket is provided with a puncture preventing means for preventing a needle tube from puncturing. 12. A syringe assembly comprising: the syringe according to claim 1; and a device connected to the connection portion after the breakage and for taking out a liquid from the inside of the syringe main body. Three-dimensional. 13. The syringe assembly according to claim 12, wherein the device has a holder provided with a needle tube communicating with the inside of the syringe body when the device is connected to the connection portion. 14. The syringe assembly according to claim 12, further comprising connection state maintaining means for maintaining a state in which the device is connected to the connection portion.