JPH08304408A - Preparative distribution system for specimen - Google Patents

Abstract

PURPOSE: To enable preparative distribution of a specimen efficiently, accurately and at a high speed. CONSTITUTION: A specimen is received and sorted in a receiving process A and the specimen finished with the sorting is dispensed in a dispensing process B. In other words, in the receiving process A, sorting information on the specimen held by a specimen holding section of a specimen rack for sorting is stored into a DC of the specimen rack for sorting and the sorting information is read out of the DC by a DCR and a sorting device determines a sorting destination based on the sorting information read out. In the dispensing process B, the specimen finished with the sorting is housed into the specimen rack and dispensing information on the specimen is stored into the DC of the specimen rack. The dispensing information is read out from the DC of the specimen rack by the DCR to perform a dispensing of the specimen by a dispensing unit based on the dispensing information.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a sample dispensing and dispensing system for inspecting components in a sample such as blood, plasma, serum, etc., from an original container containing a sample into a dispensing container. is there.

[0002]

2. Description of the Related Art Samples such as blood, plasma, and serum collected at medical institutions are stored in a sample container (generally, a diameter of 10 mm to
It is placed in a test tubular container (up to 16 mm), labeled with a sample number for identifying the sample, and sent to a sample laboratory. On the other hand, the sample test request form in which the test items and the like are entered is also sent to the sample laboratory, and the entered test instruction information is input to the host computer.

The host computer sets the inspection number of the sample according to the inspection instruction information of the sample and outputs an inspection number label consisting of the sample number and the inspection number. Further, after calculating and storing the position information of the sample corresponding to the sample container rack in which the sample is set, an inspection instruction sheet including the sample position information and the inspection number is output. The above-mentioned test number label is attached to the sample container to which the sample number displayed on the label is attached by the operator. Then, this sample container is accommodated in the sample rack and set by the operator in the precision dispenser. The precision dispenser performs sample dispensing work based on the test number and sample position information received from the host computer, etc., and also performs the test by the automatic analyzer that stores the sample position information.

The test result of the sample thus obtained is sent to the host computer, output as a report, and sent to the test orderer.

[0005]

However, since the sample racks used in the above-mentioned sample dispensing work contain the samples to be subjected to various tests in a mixed manner, efficient dispensing is possible in the precision dispensing machine. I could not do the work. In addition, there is a problem that it is unavoidable within a certain range that an operator mistakes the sample container rack when the sample container rack is mounted on the precision dispenser.

An object of the present invention is to make it possible to dispense a specimen efficiently, accurately, and at high speed.

[0007]

According to a first aspect of the present invention, there is provided a sample sorting / distributing system, wherein a sample sorting unit sorts the samples based on sorting information of the samples, and a plurality of samples holding the samples sorted by the sample sorting unit. A sample rack having a storage unit and a storage medium for storing the dispensing information for each sample held by these sample holding units, and dispensing is required by reading the dispensing information from the storage medium of this sample rack A discriminating unit that discriminates whether or not the sample is stored in this sample rack, and if the discriminating unit determines that a sample that requires dispensing exists, the sample is dispensed based on the dispensing information. And a pouring means.

A sample sorting / distributing system according to a second aspect of the present invention is a sample sorting unit of the sample sorting / distributing system according to the first aspect, which has a sample holding unit and sorts the samples held by the sample holding unit. Sorting sample rack having a storage medium for storing information, sorting information reading means for reading sorting information from the storage medium of the sorting sample rack, and sorting destination determination for determining sorting destination based on the read sorting information And means.

Further, in the sample sorting / distributing system according to claim 3, the sorting information of the sample sorting / distributing system according to claim 1 or 2 states that the sample held in the sample holding portion of the sorting sample rack. It is characterized in that it includes an inspection item to be carried out for.

Further, in the sample preparative distribution system according to claim 4, in the dispensing information of the sample preparative distribution system according to claim 1 or 2, the sample number for each sample and the sample having this sample number It is characterized in that it includes the position information of the sample holding unit of the existing sample rack and the inspection item to be performed on the sample having the sample number.

Further, a sample sorting / distributing system according to a fifth aspect is the sorting / distributing system according to any one of the first to fourth aspects, in which sorting information is stored for each specimen. An information storage unit, a first detection unit for detecting a sample contained in the sorting sample rack, and sorting information for the sample detected by the first detection unit is read out from the sorting information storage unit and a sorting sample rack is provided. It is characterized in that it is provided with a sorting information writing means for writing in the storage medium.

Further, the sample dispensing / distributing system according to claim 6 further stores the dispensing information for each sample in the sample sorting / distributing system according to any one of claims 1 to 4. Dispensing information storage means, second detecting means for detecting the specimen contained in the specimen rack, and dispensing information for the specimen detected by the second detecting means is read out from the dispensing information storage means. And a dispensing information writing means for writing in the storage medium.

Further, the sample preparative distribution system according to claim 7 is the same as the sample preparative distribution system according to claim 6, further comprising:
It is characterized by comprising a dispensing result writing unit for writing the dispensing result of the sample by the dispensing unit into a storage medium included in the sample rack.

Further, in the sample dispensing / distributing system according to claim 8, the dispensing result writing means of the sample dispensing / distributing system according to claim 7 further stores the dispensing result in the dispensing information storage means. It is characterized by writing.

Further, in the sample preparative distribution system according to claim 9, in the sub sample rack that holds the sub sample that has been dispensed according to the dispensing result of the sample preparative distribution system according to claim 7 or claim 8. It is characterized in that it includes position information of the sample holding unit.

[0016]

According to the sample dispensing / distributing system of claim 1, the samples sorted by the sample sorting means are stored in the sample rack, and the dispensing information for each of the stored samples is stored in the storage medium of the sample rack. Since the dispensing is performed by storing the information and reading the dispensing information from the storage medium, the sorted sample can be dispensed and the dispensing work can be efficiently performed.

According to the sample sorting / distributing system of the second aspect, the sorting sample rack having a storage medium for storing the sorting information of the samples held by the sample holding unit is used, and the sorting information is stored from this storage medium. Since the specimens are sorted by reading out, the specimens can be sorted accurately and at high speed.

Further, according to the sample sorting / distributing system of the third aspect, since the sorting information includes the test item to be performed on the sample held in the sample holding section, the sorting for each test item is performed. Will be possible.

Further, according to the sample sorting / distributing system of claim 4, the dispensing information includes the sample number of each sample, the position information of the sample holding section of the sample rack in which the sample having this sample number exists, and the sample. Since it includes the inspection items to be performed on the sample with the number, it is possible to know the position of the sample on the sample rack based on the sample number, and to dispense for the sample at that position. it can.

Further, according to the sample sorting / distributing system of the fifth aspect, the sample contained in the sample rack for sorting is detected, and sorting information for the detected sample is read from the sorting information storage means to sort the sample. Since the information is written in the storage medium of the sample rack, the sorting information can be written accurately.

Further, according to the sample sorting / distributing system of the sixth aspect, the sample contained in the sample rack is detected, and the dispensing information for the detected sample is read from the dispensing information storage means. Since the information is written in the storage medium of the rack, the dispensing information can be written accurately.

Further, according to the sample dispensing / distributing system of the seventh aspect, since the sample dispensing result of the sample dispensing means is written in the storage medium of the sample rack, the sample rack discharging process is performed based on the dispensing result. And so on.

Further, according to the sample dispensing / distributing system of the eighth aspect, since the dispensing result is written also in the dispensing information storage means, the dispensing result is used for subsequent inspections and the like. You can

Further, according to the sample dispensing / distributing system of the ninth aspect, since the dispensing result includes the position information of the sample holding unit in the subsidiary sample rack holding the dispensed subsidiary sample, the subsequent inspection is performed. The position information of the sub-sample rack can be used for.

[0025]

Embodiments of the present invention will be described below with reference to the drawings.

FIG. 1 shows the processing steps of a sample test in a sample laboratory.

At the sample laboratory, first, the sample received from the test orderer of each medical institution or the like is received, and sorting is performed based on the test item and the like (reception step A). Next, the sample is dispensed in the sub-sample container, the measurement container, or the like in an amount necessary for the test (dispensing step B). Next, the sample dispensed into the sub-sample container is measured based on the inspection item (measurement step C), a report is prepared (report preparation step D), and the inspection orderer is notified.

FIG. 2 is a diagram for explaining the detailed processing steps in the sample receiving step A and the flow of the sample, the test request form and the test information. In the figure, reference numeral A1 indicates the unpacking process, and the sample box 40 sent from each sales office
Unpack. The sample BOX 40 contains a sample 42 and an inspection request form 43, and the inspection request form 43 is delivered to the batch assembling process A2 and the sample 42 is delivered to the main sorting process A4.

In the batch assembling step A2, the inspection request form 43 is batch-assembled and the sample BOX 40 and the inspection request form 43 batch are linked. After the processing in the batch assembly process A2 is completed, the inspection request form 43 is delivered to the input process A3, and basic information (inspection items, inspection materials, etc.) in the information described in the inspection request form 43 is input. Be done.

In the large sorting step A4, the specimen 42 is sorted into a normal preservation specimen and a frozen specimen based on the basic information input in the input step A3. Here, the normally preserved specimen is a specimen that does not require cryopreservation due to the characteristics of the test items. In addition, the frozen sample is a sample that requires cryopreservation due to the characteristics of test items.

Note that normally preserved specimens include single specimens that perform one type of examination for one specimen and other specimens.

The single specimen is sorted in the sorting step A5 based on the above-mentioned basic information. On the other hand, the frozen sample is sorted in the frozen sorting step A6 based on the above basic information. Sorting process A5 and freezing sorting process A
The sample 42 that has been sorted in 6 is carried into the sample dispensing system installation room 1 (see FIG. 4) in the sample dispensing system installation room carrying-in step A7.

FIG. 3 is a view for explaining the detailed processing steps in the dispensing step B of FIG. 1, and FIGS. 4 and 5 are
It is a figure for demonstrating the layout of the sample dispensing system installation room 25 in which the sample dispensing system which performs the process of the dispensing process B is installed.

The sample 42 taken over from the receiving process A is
In the carry-in processing step B1, and in the re-test preparation step B2, the sample 42 requested for re-examination from each inspection room is carried into the sample dispensing system installation room 25 from the sample carry-in / out port 26. The carried-in sample 42 is made to stand by in the carried-in sample waiting area 27 until it is put into the dispensing pretreatment process B3. The dispensing pretreatment process B3 is performed in the dispensing pretreatment process area 28. In this dispensing pretreatment process area 28, a defroster 28a and a stirrer 28b are installed, and a dispensing pretreatment workbench 28c is also installed.

For the sample 42 for which the pre-dispensing process has been completed,
The rack assembling process is performed in the rack assembling step B4. This rack assembly process is performed in the rack assembly process area 29 provided adjacent to the pre-dispensing process area 28. In this rack assembly process area 29, a rack assembly device 29a is provided in which a worker carries out a rack assembly process. In addition, between the pre-dispensing treatment process area 28 and the rack assembling process area 29, an automatic transporting vehicle in which an automatic carrier for transporting the sample 42 after the pre-dispensing treatment process B3 to the rack assembling process B4 runs A vehicle travel route 30 is provided. Further, in front of the rack assembly device 29a, a rack transport conveyor 29b for transporting the sample 42, for which the rack assembly process has been completed, to the dispensing area 31 where the dispensing process is performed.
Is installed.

For the sample 42 for which the rack assembly process has been completed, a dispensing line process B5 in the dispensing area 31, that is, an empty rack supply process (B5a), a dispensing process (B5b), an abnormal sample extracting process (B5c) and The sample storage process (B5d) is performed.

FIG. 5 is for explaining the details of the dispensing area 31, and in this dispensing area 31, a rack loading device 31a is installed in contact with the rack transport conveyor 29b. Rack conveyor 2 in this dispensing area 7
Downstream of 9b, a section dispensing unit F in which the volume determination dispensing unit 31b and the section dispensing unit 31c are installed and a pre-dispensing unit G in which the pre-dispensing unit 31d is installed are provided.

Here, the section dispensing is a dispensing that does not require quantitative accuracy, and the pre-dispensing is a dispensing that requires quantitative accuracy.

Each section dispensing unit 31c,
Sample 42 to be dispensed in the pre-dispensing unit 31d
Are determined based on the inspection items performed on the sample 42.

Further, in the section pipetting unit F, a rack pulling device 31 for pulling the BC-equipped sample rack 68 into the rack transport conveyor 29b of the section pipetting unit F.
e is installed, and a rack discharge device 31f is provided at the end of the rack transport conveyor 29b of the section dispensing section F and the pre-dispensing section G.

In FIG. 3, B6 indicates a holding process step, and the sample 42 in which an error has occurred in the dispensing line processing step B5 is held in the holding process area 32.

Furthermore, this sample dispensing system installation room 2
5 is provided with a sample temporary storage area 33 for temporarily storing the sample 42, and a carry-out sample waiting area 34 for waiting the sample 42 for which the dispensing has been completed from the sample dispensing system installation room 25.

The sub-samples dispensed from the sample 42 are
In order to carry it into each examination room, it is carried out from the sample dispensing system installation room 25 in the carry-out processing step B7.

Next, with reference to FIG. 6, the configuration of a computer for controlling the receiving step A of the sample sorting / distributing system of this embodiment will be described.

In the figure, reference numeral 1 is a backbone host computer, and in addition to this receiving step A, control of a dispensing step B and the like for dispensing the samples 42 received and sorted in this receiving step A Do. Further, in the figure, the reference numeral 2 denotes a reception host computer, and the reception host computer 2 controls the entire reception process A.

The reception host computer 2 is connected to the backbone host computer 1, which is a higher-level computer, via the connection cable 10. In addition, the reception host computer 2 includes an unpacking process management computer 3, a batch assembly process management computer 4, a large sorting process management computer 6, a sorting process management computer 7, and a freezing sorting process, which are subordinate computers via the connection cable 10. A process control computer 8 is connected. An input process management computer 5 is connected to the core host computer 1 via a connection cable 10.

Here, the unpacking process management computer 3 is
The work of the unpacking process A1, the batch assembling process management computer 4 sorts the work of the batch assembling process A2, the large sorting process management computer 6 sorts the work of the large sorting process A4, and the sorting process management computer 7 sorts. The freeze-free sorting process management computer 8 manages the work of the process A5, and the input process management computer 5 manages the work of the input process A3 (see FIG. 2).

Next, referring to FIGS. 7 to 12, the unpacking process management computer 3, the batch assembly process management computer 4,
The respective configurations of the input process management computer 5, the large sorting process management computer 6, the sorting process management computer 7, and the frozen-freezing sorting process management computer 8 will be described.

FIG. 7 is a block diagram showing the configuration of the unpacking process management computer 3. The unpacking process management computer 3 is provided with a CPU 3a for controlling the entire unpacking process management computer 3. This CPU3a
Includes a key input unit 3b, a storage unit 3c, and a label printer 3
d and the display unit 3e are connected. Further, a bar code (hereinafter, referred to as BC) read by a wireless bar code reader (hereinafter, referred to as wireless BCR) 3f can be input to the unpacking process management computer 3.

The key input section 3b is provided with a ten-key pad (not shown) for inputting whether the sample is stored (room temperature, refrigerated or frozen). Further, the storage unit 3c stores the sample BOX management number, the position information of the storage shelf 44 in which the sample BOX 40 is stored, and the like. Further, the label printer 3d outputs the BOX management label in which the barcode attached to the sample BOX 40 is displayed, and the display unit 3e displays the B read by the wireless BCR 3f.
The OX management number etc. are displayed. Further, the unpacking process management computer 3 also controls the storage shelf 44 for storing the sample BOX 40.

FIG. 8 shows the batch assembly process management computer 4.
FIG. 3 is a block diagram showing the configuration of FIG. The batch assembly process management computer 4 includes the batch assembly process management computer 4
A CPU 4a for controlling the whole is provided. The CPU 4a includes a key input section 4b, a storage section 4d and a B section.
CR4c is connected. The key input unit 4b is provided with a numeric keypad (not shown) for inputting the number of batches and the like of the batch associated with one sample box 40. The BCR 4c reads the BC indicating the management number of the sample BOX 40 displayed on the sample BOX 40 and the BC indicating the batch number displayed for each batch. Further, the storage unit 4d temporarily stores the management number of the sample box 40, the number of batches, and the like.

FIG. 9 is a block diagram showing the configuration of the input process management computer 5. The input process management computer 5 is provided with a CPU 5a for controlling the entire input process management computer 5. This CPU 5a
A key input unit 5b and a storage unit 5c are connected to. The key input unit 5b is for inputting a sample number (ID-0) and basic information (inspection item, inspection material, etc.) among the items described in the inspection request form 43. Here, the sample number (ID-0) is a number unique to the sample. The storage unit 5c temporarily stores the data input by the key input unit 5b.

FIG. 10 is a block diagram showing the configuration of the large-scale sorting process management computer 6. The large sorting process management computer 6 is installed in each large sorting device 52, and the large sorting process management computer 6 is provided with a CPU 6a for controlling the entire large sorting process management computer 6. ing. The BCR 6b and the storage unit 6c are connected to the CPU 6a. Further, the CPU 6a includes an LED 6e, a data carrier writer (hereinafter referred to as DCW) 6f, and a gate sensor 6g.
Is connected.

Here, the BCR 6b reads the BC indicating the sample number attached to the sample 42.
Further, the storage unit 6c stores sorting information for sorting the samples 42 received from the reception host computer 2. Furthermore, the LED 6e displays the sorting destination of the sample 42, and the DCW 6f writes sorting information to the data carrier (hereinafter referred to as DC) 46 of the sample rack 45 when the sample 42 is a single sample. belongs to. Further, the gate sensor 6g is for detecting whether or not the sorting destination of the sample 42 is correct.

FIG. 11 shows the sorting process management computer 7.
FIG. 3 is a block diagram showing the configuration of FIG. The sorting process management computer 7 is installed in each sorting device 54, and the sorting process management computer 7 is provided with a CPU 7a for controlling the entire sorting process management computer 7. The CPU 7a includes a data carrier reader (hereinafter referred to as DCR) 7b and a label printer 7.
c and the sample sensor 7d are connected. Also, CPU
7a includes an LED 7 provided for each sorting destination of the specimen 42.
e and the gate sensor 7f are connected.

Here, the DCR 7b reads the sorting information from the DC 46 of the sample rack 45. Also,
The label printer 7c outputs a label attached to the sample 42. Further, the sample sensor 7d detects whether or not the sample 42 is extracted from the sample rack 45. The LED 7e displays the sorting destination of the sample 42, and the gate sensor 7f detects whether the sorting destination of the sample 42 is correct.

FIG. 12 is a block diagram showing the configuration of the frozen-freezing sorting process control computer 8. The frozen-freezing sorting process management computer 8 is installed in each frozen-freezing specimen sorting device 56.
Is provided with a CPU 8a for controlling the entire frozen-freezing sorting process management computer 8. This CPU 8a
Includes a DCR 8b, a label printer 8c, and a storage unit 8d.
Is connected.

Here, the BCR 8b reads the BC indicating the sample number attached to the sample 42.
Further, the label printer 8c outputs an inspection number label to be attached to the sample 42. Further, the storage unit 8d stores sorting information for sorting the samples 42.

Next, with reference to FIG. 13, the configuration of a computer for controlling the dispensing step B of the sample dispensing / distributing system of this embodiment will be described.

In the figure, the reference numeral 1 indicates a backbone host computer, which controls the dispensing step B and the above-mentioned receiving step A and the like. Further, in the figure, reference numeral 16 is a dispensing host computer, and the entire dispensing process B is controlled by this dispensing host computer 16.

The dispensing host computer 16 is connected to the backbone host computer 1, which is a higher-level computer, via the connection cable 10. Further, the dispensing host computer 16 is connected to the dispensing preprocessing management computer 17, which is a subordinate computer, via the connection cable 10.
A rack assembly device management computer 18, a rack loading device management computer 19, a rack drawing device management computer 20, a dispensing unit management computer 21, and a rack ejection device management computer 22 are connected.

Here, the dispensing pretreatment management computer 17
Is used for the work of the dispensing pretreatment process, and is installed on each dispensing pretreatment workbench 28c. Further, the rack assembly apparatus management computer 18 uses the rack assembly apparatus 29a.
And is installed close to each rack assembly device 29a. The rack loading device management computer 19 controls writing of data to the data carrier (hereinafter referred to as DC) 69 by the rack loading device 31a, and is installed in the vicinity of the rack loading device 31a. Further, the rack pull-in device management computer 20 transfers the BC-attached sample rack 68 transported by the transport conveyor 29b to the section dispensing unit section F.
Rack retractor 3 for retracting to the conveyor 29b
1e is controlled.

Further, the dispensing unit management computer 21
Controls the volume determination dispensing unit 31b, the section dispensing unit 31c, and the pre-dispensing unit 31d, and is installed close to each dispensing unit 31b, 31c, 31d. The rack ejecting device management computer 22 controls the ejection of the rack by the rack ejecting device 31f, and is installed near the rack ejecting device 31f.

The dispensing host computer 16 has
It is also possible to input data from the wireless terminal 23.

Next, referring to FIGS. 14 to 19, a pre-dispensing process management computer 17, a rack assembly device management computer 18, a rack loading device management computer 19, a rack drawing device management computer 20, a dispensing unit management computer 21. The respective configurations of the rack ejecting device management computer 22 will be described.

FIG. 14 shows the dispensing preprocessing management computer 1.
7 is a block diagram showing the configuration of No. 7. This dispensing pretreatment management computer 17 includes the dispensing pretreatment management computer 1
A CPU 17a for controlling the whole 7 is provided. A key input unit 17b, a storage unit 17c, a BCR 17d, and a label issuing unit 17e are connected to the CPU 17a. The key input unit 17b is provided with a ten-key pad (not shown) for inputting the sample number. In addition, the storage unit 17c stores character data and the like for issuing the sample number. Furthermore, BCR17
d is for reading the barcode attached to the sample 42.
The label displaying the same sample number as the sample number read in d is issued.

FIG. 15 is a block diagram showing the configuration of the rack assembly apparatus management computer 18. The rack assembly apparatus management computer 18 is provided with a CPU 18a for controlling the entire rack assembly apparatus management computer 18. The CPU 18a includes a key input unit 18b, a storage unit 18c, a self-propelled BCR 18d, and a beam sensor 1.
8e is connected. The sample 4 is displayed on the key input unit 18b.
A bar code reading start key (not shown) attached to the key 2 is provided. In addition, in the storage unit 18c,
The sample number and the dispensing information for each sample are stored. Further, the self-propelled BCR 18d is for reading the barcode attached to the sample 42, and the beam sensor 18e is for detecting the presence or absence of the sample 42 for reading the barcode.

FIG. 16 is a block diagram showing the configuration of the rack loading device management computer 19. The rack loading device management computer 19 is provided with a CPU 19a for controlling the entire rack loading device management computer 19. The CPU 19a includes a data carrier reader / writer (hereinafter referred to as DCRW) 19b,
The BCR 19c and the storage unit 19d are connected. DC
The RW 19b writes the sample number and the dispensing information for each sample in the DC 69. Further, the storage unit 19d is a DC
The RW 19b stores the sample number and the dispensing information for each sample written in the DC 69.

FIG. 17 is a block diagram showing the configuration of the rack pull-in device management computer 20. The rack pull-in device management computer 20 has a CP for controlling the entire rack pull-in device management computer 20.
U20a is provided. This CPU 20a has a D
Whether or not the sample rack 68 with BC is pulled into the transport conveyor 29b of the section pipetting section F, based on the sample number and the pipetting information for each sample stored in the DC69 that is connected to the CR20b and read by the DCR20b Make a decision.

FIG. 18 is a block diagram showing the configuration of the dispensing processing unit management computer 21. The dispensing processing unit management computer 21 includes a CPU 21 for controlling the entire dispensing processing unit management computer 21.
a is provided. This CPU 21a has a DCRW
21b, the memory | storage part 21c, and BCR21 are connected. The DCRW 21b reads the dispensing information stored in the DC 69 and writes the dispensing result in the DC 69. Further, the storage unit 21c stores the dispensing information read from the DC 69.

FIG. 19 is a block diagram showing the configuration of the rack ejection device management computer 22. The rack ejection device management computer 22 includes a CPU 22a for controlling the entire rack ejection device management computer 22. This CPU 22a has a BCR 22b,
The DCRW 22c and the storage unit 22d are connected. B
The CR22b reads the rack number attached to the BC-attached sample rack 68, and the DCRW22c
Reads the dispensing information stored in the DC 69. Further, the storage unit 22d stores the dispensing information read from the DC 69.

Next, the details of the unpacking process A1 (see FIG. 2) of the receiving process A will be described with reference to FIGS. 7 and 20 to 22. First, as shown in FIG. 21, the sample BOX 40 carried into the sample laboratory is unpacked (S1), and the sample BOX number displayed on the sample BOX 40 is read by the wireless BCR 3f (S2). Also, the key input unit 3
Based on b, the storage state of the sample BOX 40 (room temperature, refrigerated, frozen) is input (S3). Thereby, the storage unit 3c
A BOX management number composed of the sample BOX number and the storage state of the sample BOX is stored in. On the other hand, the BOX in which the BOX management number is displayed by the label printer 3d
The management label is output (S4).

This BOX management label is affixed to the BOX input management form 47, and taken over to the batch assembly process together with the inspection request form 43 taken out from the sample BOX 40 (S6). On the other hand, the sample BOX 40 is delivered to the management in the storage shelf 44 (S7).

In managing the storage rack 44, first, the storage rack 44 for storing the sample BOX number and the sample BOX 40 displayed on the sample BOX 40 by the wireless BCR 3f.
The BC indicating the storage position displayed at each storage position is read (S8, S9). As a result, the sample BOX 40 and the storage position of the storage rack 44 can be linked, and the storage rack position number corresponding to the BOX management number is stored in the storage unit 3c (see FIG. 22). The sample box 40 is
The product is stored in the storage position where the storage rack position number is read (S10).

Next, in the input step A3, when all the inputs to the batch associated with the sample BOX 40 are completed, the sample BOX number is transmitted from the reception host computer 2 as the sample BOX 40 that can be delivered. , Whether or not the sample BOX number is received is detected (S1
1). When the sample box number is received, the CPU 3a
Is the sample BO having this sample BOX number in the storage shelf 44.
The lamp at the position where X is stored is turned on (S1).
2). As a result, the sample BOX 40 on the corresponding shelf is taken out from the storage shelf 44 and delivered to the main sorting step A4 (S13, S14).

Next, the details of the process of the batch assembling process A2 (see FIG. 2) of the receiving process A will be described with reference to FIGS. 8 and 23 to 25. First, as shown in FIG. 24, the inspection request form 43 contained in one sample BOX 40 received from the unpacking step A1 is divided into a plurality of batches, and each batch has a batch management number (for example, 1001, 1002).
Etc. is attached to the batch input management slip 48 (S2
0).

Next, the sample BOX 40 and the batch are linked. That is, the BOX input management form 4 by the BCR 4c
The BOX management number is read from 7 (S21). In addition, the sample BOX of this BOX management number
The number of batches associated with 40 is input (S22). Furthermore, B
The CR4c reads batch management numbers from the batch input management slip 48 for the number of batches (S23, S24). By this process, the storage unit 4d stores the BOX management number
The number of batches and the batch management number are stored (see FIG. 25).

The inspection request form 43 in which the linking of the sample BOX 40 and the batch is completed is the batch input management form 4 for each batch.
8 is attached and it succeeds to the input process A3 (S25).

The batch assembly process management computer 4 receives the finished batch number transmitted by the input process management computer 5 when the input of the basic information of all inspection request forms 43 of one batch is completed (S26), and stores it. Finished information (“Done” shown in the figure,
“Un” is written (see FIG. 25). When the input for all batches associated with the BOX management number is completed, the BOX management number of the sample BOX 40 that has been input is transmitted to the unpacking process management computer 3 (S27, S).
28).

Next, the details of the process of the input step A3 (see FIG. 2) of the receiving step A will be described with reference to FIGS. 9 and 26 to 27. In the input process A3, each inspection request form 4
Of the items described in item 3, items related to basic information are input in batch units (S35, S36). As a result, the storage unit 5c stores the sample number for each batch management number and the basic information of the inspection request form 43 in which the sample number is displayed (see FIG. 27). When the basic information on all the request forms included in one batch has been entered (S
37), the batch management number of this batch is transmitted to the batch assembling process management computer 4 as a finished batch number (S38). On the other hand, the sample number and the basic information stored corresponding to this sample number are transmitted to the basic host computer 1 via the CPU 5a.

Next, the details of the processing of the main sorting process A4 and the sorting process A5 (see FIG. 2) of the receiving process A will be described.

Here, the structure of the sample rack 45 used in the large-scale sorting step A4 and sorting step A5 will be described with reference to FIGS. 28 and 29.

The sample rack 45 is composed of a bottom plate part 45a having a disc shape and a cylindrical sample holding part 45b provided upright at the center of the bottom plate part 45a. A circular recess 45c is provided on the bottom surface of the bottom plate portion 45a, and
46 are housed. On the other hand, on the upper surface of the bottom plate portion 45a, a standing portion 45d is provided on the outer peripheral edge portion of the bottom plate portion 45a.

The sample holding unit 45b holds one sample, and the diameter of the tube of the sample holding unit 45b is set to a plurality of types so that a plurality of types of samples 42 can be held. Is formed larger than the diameter of the specimen 42.

The sample rack 45 stores the sorting information of the samples 42 held in the sample rack 45 in the DC 46 provided in the rack, so that the samples 42 are sorted accurately and at high speed. be able to. Further, since the bottom plate portion 45a of the sample rack 45 has a disc shape, it can be smoothly transported by the conveyor. Further, DC is attached to the bottom surface of the bottom plate portion 45a of the sample rack 45.
Since 46 is provided, the sorting information can be easily read even during the transportation by the conveyor. Further, since the bottom plate portion 45a of the sample rack 45 is provided with the standing portion 45d, the carrying direction can be easily changed by hooking the standing portion 45d with a hook or the like.

The DC 46 described above is a disk-shaped member having a predetermined thickness and has a built-in EEP-ROM (nonvolatile memory). The writing and reading of data with respect to the DC 46 can be performed by DCRW without contact.

Next, with reference to FIGS. 10 and 28 to 33, the processing of the large sorting step A4 will be described. First, before starting the processing of the large-scale sorting process A4, the large-scale sorting process management computer 6 determines whether the basic information and the patient information (see FIG. 30) for each sample number stored by the core host computer 1. The basic information is stored in the storage unit 6c via the reception host computer 2 (see FIG. 31).

The sample 42 is taken out from the sample BOX 40,
The sample number attached to the sample 42 is read by the BCR 6b (S45). The CPU 6a acquires the sorting information corresponding to the sample number read from the storage unit 6c, that is, basic information (S46).

The CPU 6a determines the sorting destination on the basis of the obtained sorting information, and the LED of the large sorting device 52.
Either 6e is turned on (S47). That is, sample 4
When 2 is a single sample, the LED 6e installed in front of the DCW 6f is turned on, and when it is a frozen sample, the LED 6e installed in front of the gate sensor 6g is turned on.

When the LED 6e installed in front of the DCW 6f is turned on, the worker returns one sample rack 45 returned from the sorting device 54 by the rack return conveyor 58 and stored in the rack storage section 59. take,
The sample 42 is set on the sample rack 45 (see FIG. 28). This sample rack 45 is placed on the DCW 6f,
Sorting information for the samples 42 set in the sample rack 45 is written in the DC 46 (S48, S4).
9, S50). The sample rack 45 for which the sorting information has been written to the DC 46 is automatically transferred to the transport conveyor 5
7 (S51) and conveyed to the sorting device 54.

On the other hand, when the LED 6e installed in front of the gate sensor 6g is turned on, the sample 42 is passed between the gate sensors 6g and is put into the wire net rack 60 (S48). The above-described large sorting process of the sample 42 is 1
This is continued until the sorting of all the samples 42 contained in one sample BOX 40 is completed (S52).

Next, the processing of the sorting step A5 (see FIG. 2) of the receiving step A will be described with reference to FIGS. 11 and 34 to 36.

The conveyor conveyor 5 is operated by the large sorting device 52.
The sample rack 45, which has been loaded into the No. 7 and transported by the transport conveyor 57, has a stopper 62 installed on the transport conveyor 57 in front of the sorting information reading device 61.
Is caused to stay on the transport conveyor 57 (S6
0). When 10 sample racks 45 accumulated by the stopper 62 are accumulated (S61), the DCR 61a provided in the sorting information reading device 61 causes each of the DCs 46 of the 10 sample racks 45 to detect each sample 42. The sorting information is read (S62).

Here, the sorting information reading device 61
Is controlled by the reception host computer 2, and the read sorting information for 10 samples is stored in a storage unit (not shown) of the reception host computer 2. Here, the reception host computer 2 generates a branch sequence based on the sorting information for 10 samples stored in the storage unit (the sample is classified by the generation of this sequence) (S63), and this branch is performed. The sequence is transmitted to the sorting process management computer 7 provided in each sorting device 54.

Thereafter, the stopper 62 is opened to release the retention of the sample rack 45 (S64). The sample rack 45 whose retention is released is transported to each sorting device 54 by the transport conveyor 57. Each sorting device 5
4 draws the sample rack 45 into the sorting apparatus 54 based on the branch sequence transmitted by the reception host computer 2 (S65). That is, each sorting device 54 divides the sample rack 45 drawn into the sorting device 54 into the branching device 6.
3 to branch to the branch conveyor 64 (see FIG. 35). For example, of 10 sample racks, the first and 3
The second sample rack is drawn into the sorting device 54 located closest to the front in the transport direction.
When the first sample rack is pulled into the second sorting device 54 from the front in the transport direction, the first and third sample racks 45 are sorted in the foremost direction in the transport direction. Retracted into device 54,
Further, the second sample rack is drawn into the second sorting device 54 from the front in the transport direction.

The sample rack 45 drawn into each sorting device 54 is conveyed to the position of DCR 7b by the branch conveyor 64 (see FIG. 36). Here, the sample 4 stored in the sample rack 45 stored in the DC 46
The sorting information of No. 2 is read (S66). As a result, the CPU 7a determines the sorting destination and turns on the LED 7e of the corresponding sorting destination. Further, the label printer 7c outputs an inspection number label displaying the inspection number (ID-1) of the sample 42 (S68). In addition,
The inspection number (ID-1) is a number composed of letters and numbers representing an inspection room, inspection items, and the like.

Here, the worker removes the sample 42 from the sample rack 45 and displays the output inspection number label on the sample 42.
Then, the sample 42 is put into the wire net rack 60 of the sorting destination whose LED 7e is lit (S69, S70).
The CPU 7a detects with the gate sensor 7f whether or not the sample 42 is correctly sorted into the sorting destination. Also,
The sample sensor 7d detects whether the sample 42 has been extracted from the sample rack 45 (S71). Here, when it is detected that the sample 42 is extracted (S7
2) The sample rack 45 is dropped on the rack return conveyor 58 provided below the DCR 7b (S73).

As a result, the sample rack 45 is conveyed by the rack return conveyor 58 to the large sorting device 52 and is stored in the rack storage portion 59 of the large sorting device 52.

Next, the processing of the frozen-freezing sorting step A6 (see FIG. 2) of the receiving step A will be described with reference to FIGS. 12 and 37 to 38.

Frozen samples are 50 or more from the large sorting step A4.
The wire mesh rack 60 containing the book is carried over to the frozen-freezing sorting step A6 (S85). At this point, the sorting information regarding the frozen sample received from the core host computer 1 and transmitted via the host computer 2 is stored in the storage unit 8d of the frozen frozen sorting process management computer 8 in correspondence with each sample number. Remembered

The worker extracts the sample 42 from the wire mesh rack 60 (S86) and reads the sample number by the BCR 8b (S87). The CPU 8a uses the sample number and storage unit 8
Based on the sorting information stored in d, the label printer 8c outputs an examination number label displaying the examination number (ID-1) of the sample 42 (S88) and turns on the LED 8e of the corresponding sorting destination ( S89).

Here, the worker pulls out the sample 42 from the wire mesh rack 60 and displays the output inspection number label on the sample 42.
The sample is put into the wire mesh rack 60 of the sorting destination whose LED 8e is lit (S90). The CPU 8a is
The gate sensor 8f detects whether or not the sample is correctly sorted and sorted by the sorting destination. This sorting operation is performed for all the specimens 42 carried into the frozen-freezing sorting step A6 (S91).

The samples 42 sorted by the sorting step A5 and the frozen-freezing sorting step A6 described above are carried into the sample dispensing system setting room 1 by the sample dispensing system setting room loading step A7.

Next, the dispensing step B (see FIGS. 1 and 3) will be described in detail with reference to FIGS. 39 to 66.

First, the structure of the BC-equipped sample rack 68 used in the dispensing step B will be described with reference to FIGS. 39 and 40.

The sample rack 68 with BC has a rectangular bottom plate 70.
The bottom plate 70 is provided with a side wall 71 extending in the transport direction, and a front wall 72 is provided at the front end of the bottom plate 70.
However, a rear wall 73 is provided at the rear end. Also, the front wall 7
Nine partition walls 74 are provided between the rear wall 73 and the rear wall 73 at equal intervals, and one end of the partition wall 74 is in contact with the side wall 71. Inner wall surfaces 72a, 73 of the front wall 72 and the rear wall 73
a, five recesses are formed on both wall surfaces 74a of the partition wall 74, and the recess of the front wall 72 and the recess of the partition wall 74 provided facing the recess, the recess of the partition wall 74, and By the recess of the adjacent partition wall 74 provided facing the recess, the recess of the partition wall 74, and the recess of the rear wall 73 provided facing the recess, 50 (5 in the carrying direction). The sample holding portions 75 are formed in rows (10 in a row).

In addition, the front wall 7 forming each specimen holding portion 75
2, on the upper surfaces of the rear wall 73 and the partition wall 74, the sample holder 7
A resin piece 76 for positioning the specimen 42 held by 5 is screwed via a metal plate 77.
The resin piece 76 can hold the sample 42 at the center of the sample holding unit 75 even when the sample 42 held by the sample holding unit 75 has a different thickness.

A storage medium holding portion 80 is provided on the outer wall surface of the side wall 71. This storage medium holding unit 8
0 has L-shaped grooves 80a on the left and right sides and the lower part, and both ends and the lower part of the DC 69 are held by the groove 80a. The DC 69 can be removed from the storage medium holding unit 80 by sliding the DC 69 upward.

Therefore, if the DC 69 is defective, the DC 69 can be easily replaced. Further, since the storage medium holding unit 80 is provided on the side wall 71, the BC-equipped sample rack 68 transported by the rack transport conveyor 29b.
It is possible to easily read and write the dispensing information with respect to the DC 69.

Further, the bar code 8 is provided on the outer wall surface of the side wall 71.
1 is displayed. The bar code 81 displays the rack number of the BC-attached sample rack 68.

The DC 69 described above is of a rectangular shape having a predetermined thickness and has a built-in SRAM and a battery for holding data. The writing and reading of data to and from the DC 69 can be performed by DCRW without contact.

Next, each process of the above-mentioned dispensing step B will be described in detail.

First, the dispensing pretreatment step (B3 in FIG. 3) will be described with reference to FIGS. 14 and 41. The sample 42 to be dispensed is the sample dispensing system installation room 2
Regarding the sample 42 that has been carried in to S5 (S110) and is carried in, the number of pieces and the like are checked based on the carry-in slip (S111).

Next, if the sample 42 is a frozen sample, it is checked whether or not it is time to thaw by the timetable showing the thaw start time for each inspection item. To the position (S112). If the specimen 42 can be thawed, it is thawed by immersing it in each of the loaded wire netting racks 60 in the water bath of the thawer 28a (S113).
The thawed sample 42 is stirred by the stirrer 28b (S114). In the case of a normally preserved sample, thawing is not necessary and only stirring (S14) is performed.

Next, the amount of the sample is checked by visual inspection to determine whether it is the eighth minute or more of the container of the sample 42 (S1).
15). If it is determined that the sample amount is 8 minutes or less in the container of the sample 42, the presence or absence of fibrin is checked (S
116), remove any fibrin (S11)
7). Next, it is checked whether or not the sample 42 is hemolyzed or not chyle (S118). When the sample 42 is hemolyzed or chyle, the information is stored in the dispensing pretreatment management computer 17. By operating the key of the key input unit 17b, the data is input to the pre-dispensing process management computer 17 (S119). Then, the sample 42 is transferred to the wire net rack 60 (S131).

On the other hand, in the above-mentioned processing of S115, when it is judged that the sample amount is 8 minutes or more of the container of the sample 42, the sample number of the sample 42 is read by the BCR 17d of the dispensing pretreatment management computer 17, Label issuing department 1
A label displaying the same sample number is issued by 7e (S120). The issued label is attached to another sample container (S121).

Next, the cap of the sample container of the sample 42 is cut off (S122), and the presence or absence of fibrin is checked (S1).
23), remove any fibrin (S12)
4). Next, it is checked whether or not the sample 42 is hemolyzed or not chyle (S125). If the sample 42 is hemolyzed or chyle, the information is sent to the dispensing pretreatment management computer 17. Input (S126).

Thereafter, the sample of the sample 42 is subdivided into the sample container to which the above-mentioned label displaying the same sample number is attached (S12).
7).

After this processing, the sample 42 is the wire mesh rack 6
0 (S131). Note that the subdivided sample container is stored together with the sample 42 after the dispensing process of the sample 42 is completed (S129, S130).

Next, the rack assembly process (B4 in FIG. 3) will be described with reference to FIGS. 15 and 42 to 46. In addition,
At the time when the rack assembly process is started, the sample information for each sample stored in the backbone host computer 1 (see FIG. 42).
Reference), that is, basic information (information such as test items and test materials stored corresponding to the sample number) and patient information (information such as patient name, sex and age stored corresponding to the sample number) Of these, basic information is input and stored in the dispensing host computer 16 as dispensing information (see FIG. 43). In the rack assembly process, as shown in FIGS. 44 and 45, the sample 42 carried on the wire net rack 60 from the pre-dispensing process B3 and transported is taken (S14).
0).

Next, the samples 42 are aligned in units of 10 on the BC-equipped sample rack 68 set on the rack assembly apparatus 29a (S141). That is, first, ten specimens 42 are aligned in the L1 row shown in FIG. Whether or not the sample 42 has been set is monitored by the beam sensors 18e provided at both ends of the rack assembling apparatus 29a.
After that, a BC reading instruction is given by operating the START button of the key input unit 18b (S142).
Thereby, the rack number of the BC-equipped sample rack 68 is read by reading the BC 81 attached to the side wall of the BC-equipped sample rack 68 by the self-propelled BCR 18d (S143). If the rack number cannot be read, the BC-equipped sample rack 68 is replaced (S144).
S145).

Next, 10 specimens 42 aligned in the L1 row of the specimen rack 68 with BC by the self-propelled BCR 18d.
The sample number of is read (S146). As a result, the rack number and the hole number are stored in association with the position on the BC-attached parent sample rack 68 where each sample 42 is set, that is, the sample number, in the storage unit 18c.

Next, the L2 row of the sample rack with BC 68, L
Ten samples 42 are arranged in the order of the third row, the fourth row, and the fifth row, and the same process is performed (S147). When reading of the sample numbers of all the samples 42 set in the BC-attached sample rack 68 is completed, the rack number and the hole number corresponding to the sample number stored in the storage unit 18c are stored in the dispensing host computer 16. Sent. Thereby, the dispensing information stored in the dispensing host computer 16 corresponds to the sample number with the parent rack number, the parent rack hole number, and the inspection item / dispensing amount (see FIG. 46).

Next, the dispensing line process (B5 in FIG. 3) will be described with reference to FIG.

First, the dispensing information is written in the DC 69 of the BC-equipped sample rack 68 (S150). That is, as shown in FIGS. 48 and 49, the BC-equipped sample rack 68 transported by the transport conveyor 29b from the rack assembly step B4.
Arrives at the rack loading device 31a, the BCR 19c
The rack number of the BC-attached sample rack 68 is read (see FIG. 16) (S165, S166). Next, the dispensing information (see FIG. 46) of the sample 42 accommodated in the BC-equipped sample rack 68 of this rack number is transferred from the dispensing host computer 16 to the rack loading device management computer 19, and is transferred to the DC 69 by the DCRW 19b. It is written (S167). The BC-equipped sample rack 68 for which the dispensing information has been written to the DC 69 is transported to the dispensing unit groups 31b, 31c, 31d by the transport conveyor 29b.

Next, the transport path of the BC-equipped sample rack 68 in the dispensing area 31 will be described with reference to FIGS. 50 and 51.

When the BC-equipped sample rack 68 for which dispensing information has been written to the DC 69 in the rack loading device 31a is transported to the rack retracting device 31e by the transport conveyor 29b, the DCR 20b (see FIG. 17).
(See the reference), the dispensing information of the DC 69 is read, and the sample 42 for section dispensing in the section dispensing section F is B
It is determined whether or not the sample rack 68 with C exists.
If it is determined that the sample 42 for section dispensing is present in the BC-equipped sample rack 68, the CPU 20
A branch instruction is issued by a and the sample rack 68 section with BC is drawn into the dispensing section F.

BC in which section dispensing is performed in each section dispensing unit 31c of the section dispensing section F
When the attached sample rack 68 is transported to the rack ejector 31f, the DCR 22c (see FIG. 19)
Reads the dispensing information stored in DC69 by
When dispensing for all the specimens 42 is completed, C
Ejection instruction is issued by the PU 22a and sample rack with BC 6
8 is discharged from the section dispensing section F.

On the other hand, when there is a sample 42 which has not been dispensed yet, it is transported to the downstream dispensing unit 31c by the transport conveyor 29b. The BC-equipped sample rack 68 for which section dispensing has been completed is transported to the pre-dispensing section G (see FIG. 51). When the BC-equipped sample rack 68 that has been pre-dispensed in each pre-dispensing unit 31d of the pre-dispensing unit G is transported to the rack ejection device 31f, the dispensation stored in the DC 69 by the DCR 22c. When the information is read and the dispensing for all the specimens 42 is completed, the CPU 22a issues a discharge instruction, and the BC-equipped sample rack 42 is discharged from the pre-dispensing section G.

Next, the volume determination dispensing, section dispensing and pre-dispensing performed in the section dispensing unit F and the pre-dispensing unit G will be described. When the BC-equipped sample rack 68 is transported to the position of the volume determination dispensing unit 31b by the transport conveyor 29b, it is determined whether or not to perform volume determination (S151 in FIG. 47). That is, as shown in FIGS. 52 and 54, the dispensing information stored in the DC 69 of the BC-equipped sample rack 68 by the DCRW 21b is stored in the CPU.
21a (see FIG. 18) is read (S170). Based on the dispensing information read here, it is determined whether or not there is a sample 42 in the BC-equipped sample rack 68 that needs to be subjected to volume determination (S171). Further, when it is determined that the sample 42 that needs to be subjected to the amount determination exists, the rack buffer 85 of the dispensing unit 31b.
It is determined whether or not there are two BC-equipped sample racks 68 (S172). If it is determined that the two BC-equipped sample racks 68 do not exist, the CPU 2
The branch command is output by 1a (S173), and the BC-equipped sample rack 68 is drawn into the dispensing unit 31b.

The amount of the sample 42 contained in the BC-equipped sample rack 68 drawn into the dispensing unit 31b is determined by
This is performed under the control of the dispensing unit management computer 21 (see FIG. 53). That is, it is determined for each of the samples 42 whether or not the sample needs the volume determination (S17).
4). If it is determined here that the sample 42 requires the amount determination, the sample is sucked up by the dispensing nozzle 86a of the dispenser 86 and it is determined whether the sample amount is normal (S175, S176), The sample is again discharged into the original sample container. When it is determined that the sample amount is not normal by the determination of the sample amount, the information is stored in the storage unit 21c. This process is performed for all 50 samples (S178), and after the process is completed, the information about the samples determined to have an abnormal sample amount is displayed by the DCRW 21b.
69 to write the sample rack 68 with BC to the conveyor 2
It is carried out to 9b (S179).

The sample 42 of the BC-equipped sample rack 68 for which the volume determination and dispensing process has been completed is the corresponding dispensing unit 31c, 3
In 1d, section dispensing (S154) or pre-dispensing (S155) is performed (see FIG. 47).

Here, section dispensing will be described with reference to FIGS. 18 and 55 to 58. When the BC sample rack 68 is transported to the position of the section dispensing unit 31c by the transport conveyor 29b, it is determined whether or not the section dispensing unit 31c performs the section dispensing. That is, as shown in FIGS. 55 and 57, the dispensing information stored in the DC 69 of the BC-equipped sample rack 68 is read by the DCRW 21b into the CPU 21a (S185). Based on the dispensing information read here, it is judged whether or not there is a specimen 42 in the BC-equipped specimen rack 68 that needs to be section dispensed by the section dispensing unit 31c (S186). .

If it is determined that there is a sample 42 that needs to be section-dispensed, it is determined whether or not two BC-equipped sample racks 68 are present in the rack buffer 85 of the dispensing unit 31c. Judgment is made (S18
7) When it is determined that the two BC-equipped sample racks 68 do not exist, it is determined whether or not the volume determination dispensing has already been performed on the specimen 42 of the BC-equipped sample rack 68. (S188). If it is determined that the volume determination dispensing has already been performed, the CPU 21a
Then, the branch command is output (S189), and the BC-attached sample rack 68 is drawn into the section dispensing unit 31c.

On the other hand, these conditions (S186, S18
7, S188) is not satisfied, the BC-equipped sample rack 68 is transported to the downstream dispenser by the transport conveyor 29b.

The section dispensing of the specimen 42 contained in the BC-equipped specimen rack 68 drawn into the section dispensing unit 31c is performed by the dispensing unit management computer 21.
(See FIG. 56). That is, it is determined for each sample 42 whether or not the sample requires section dispensing by the dispensing unit 31c of this section (S190). If it is determined here that the sample requires section dispensing, it is determined whether or not the sample is determined to be normal by the amount determination (S191). If the sample is determined to be empty or the sample amount is insufficient by the amount determination, the sample is delivered to the holding step (B6 in FIG. 3).

On the other hand, in the case of the sample for which the amount determination is judged to be normal, the sample is sucked up by the dispensing nozzle 86a of the dispenser 86 (S193), and an appropriate amount of the sample is stored in the subsidiary sample container of the subsidiary sample rack 88. It exhales to 89 (S194). At this point, the inspection number (ID-1) is assigned to this sample (number setting) (S195).

Next, it is judged whether or not the sample has been dispensed to all the subsidiary sample containers 89 of the subsidiary sample rack 88 (S
196), when the sample is dispensed into all the sub sample containers 89, the sub sample rack 88 is discharged (S197) and a new sub sample rack 88 is supplied (S198). This processing is performed for all the specimens 42 to be section-dispensed by the section dispenser 31c in the specimens 42 of the BC-equipped specimen rack 68 (S199), and the dispensing result is D
While writing to C69 (S200), the dispensing result is sent to the dispensing host computer 16 (S201), and BC
The attached sample rack 68 is discharged to the transport conveyor 29b. The discharged sample rack with BC 68 is used for the transport conveyor 2
It is conveyed to the section dispenser 31c on the downstream side by 9b.

By transmitting the dispensing results to the dispensing host computer 16 described above, the dispensing host computer 1
Reference numeral 6 indicates the inspection number (ID-1), the parent rack number, the parent rack hole number, the child rack number, and the child rack hole number corresponding to the sample number (ID-0) previously attached to each sample. Will be stored (see FIG. 58).

The supply of the sub sample rack 88 will be described with reference to FIGS. 59 and 60. That is, when it is determined that the sample has been dispensed to all the subsidiary sample containers 89 of the subsidiary sample rack 88 (S196 in FIG. 56), the CPU 21a of the dispensing unit management computer 21 supplies the subsidiary sample rack 88. Instruct (S225). Along with this, the child sample rack 88 is transported from the empty rack stocker 90 by the transport conveyor 91.

The rack number (BC) of the transported child sample rack 88 is read by the BCR 21d (S
226), and is stored in the storage unit 21c of the dispensing unit management computer 21 (S227).

Next, pre-dispensing will be described with reference to FIGS. 18 and 61 to 64. The sample rack 68 with BC
The pre-dispensing unit 3 when it is transported to the position of the pre-dispensing unit 31d by the transport conveyor 29b.
In 1d, it is determined whether or not to dispense. That is, as shown in FIGS. 61 and 63, the DCRW 21b causes B
The dispensing information stored in the DC 69 of the C-equipped sample rack 68 is read by the CPU 21a (S205), and the BC-equipped specimen rack 68 is read based on the read dispensing information.
It is determined whether or not there is a sample 42 that needs to be dispensed by the pre-dispensing unit 31d (S206). When it is determined that the sample 42 that needs to be pre-dispensed exists, the dispensing unit 3
2 sample racks with BC in 1d rack buffer 85
8 is present (S20).
7) When it is determined that the two BC-equipped sample racks 68 do not exist, the CPU 21a outputs a branch command (S208), and the BC-equipped sample rack 68 is drawn into the pre-dispensing unit 31d. .

On the other hand, these conditions (S206, S20
Sample rack with BC that was judged not to meet 7)
8 is conveyed to the pre-dispensing unit 31d on the downstream side by the conveyor 29b.

B drawn into the pre-dispensing unit 31d
Pre-dispensing of the sample 42 contained in the C-attached sample rack 68 is performed under the control of the dispensing unit management computer 21 (see FIG. 62). That is, it is determined for each sample 42 whether the sample requires pre-dispensing by the pre-dispensing unit 31d (S210). If it is determined that the sample requires pre-dispensing, it is determined whether or not the sample is determined to be normal by the amount determination (S211). If the sample is empty or the sample amount is judged to be insufficient by the volume determination, the holding step (B in FIG. 3).
Handed over to 6).

On the other hand, in the case of the sample for which the amount determination is judged to be normal, the sample is sucked up by the dispensing nozzle 86a of the dispenser 86 (S213), and an appropriate amount of the sample is stored in the subsidiary sample container of the subsidiary sample rack 88. It exhales to 89 (S214). At this point, the inspection number (ID-0) and the inspection item number (ID-3) are assigned to this sample (S215). Here, the inspection item number (ID-3) is a number composed of numbers representing the measurement order and the like for each inspection item.

Next, it is judged whether or not the sample has been dispensed into all the subsidiary sample containers 89 of the subsidiary sample rack 88 (S
216), when the sample is dispensed into all the sub sample containers 89, the sub sample rack 88 is discharged (S217), and a new sub sample rack 88 is supplied by the above-described processing (FIGS. 59 and 60). (S218). This process is performed for all the specimens 42 to be pre-dispensed by the pre-dispensing machine 31d in the specimens 42 of the BC-equipped specimen rack 68 (S
219), writing the dispensing results in the DC 69 (S
220), the actual dispensing result is transmitted to the dispensing host computer 16 (S221), and the BC-equipped sample rack 68 is discharged to the transport line 29b. The discharged sample rack 68 with BC is transported to the pre-dispensing unit 31d on the downstream side by the transport conveyor 29b.

By transmitting the dispensing results to the above-mentioned dispensing host computer 16, the dispensing host computer 1
The test number (I) corresponds to the sample number (ID-0).
D-3), parent rack number, parent rack hole number, child rack number, child rack hole number, etc. are stored (see FIG. 64).

B for which section dispensing and pre-dispensing are completed
For the C-equipped sample rack 68 (S156 in FIG. 47), the sample storage process (B5c in FIG. 3, S157 in FIG. 47) is performed. That is, as shown in FIGS. 65 and 66, the BC-equipped sample rack 68 ejected from the rack ejector 31f is
It is transferred to the storage wagon 92 (S230). When the BC-equipped sample rack 68 is transferred to all the shelves of the storage wagon 92 (S231), the wagon number is read by the wireless terminal 23 and transmitted to the dispensing host computer 16 (S23).
2). In addition, all shelf numbers and rack numbers are wireless terminals 2.
3 to the dispensing host computer 16 (S23
3, S234). After this process, the storage wagon 92
Stored in the refrigerator.

On the other hand, the sub-sample rack 88 (FIGS. 57 and 63) discharged from the section dispensing section F and the pre-dispensing section G
(Refer) is carried out from the sample dispensing system installation room 25 and carried into each examination room.

According to the sample dispensing / distributing system of this embodiment, the samples are sorted by the sorting device and then stored in the sample rack with BC, and the dispensing information of the stored sample is stored in the DC of the sample rack with BC. Dispensing information in the dispensing unit D
Since it is read from C and the sample is dispensed based on this dispensing information, it is possible to dispense for the sample that has been classified, and the dispensing work for a large number of samples can be performed efficiently and accurately in a short time. Can be done

[0151]

According to the present invention, the samples sorted by the sample sorting means are stored in the sample rack having the storage medium, and the dispensing information is read from the storage medium to perform the dispensing. Therefore, it becomes possible to dispense the specimens for which sorting has been completed, and the specimens can be dispensed efficiently. Further, when the samples are sorted using the sorting sample rack having the storage medium, the samples can be sorted accurately and at high speed.

Further, when the sorting information includes the test items to be carried out on the sample held in the sample holding section, it becomes possible to sort each test item. Further, in the case where the dispensing information includes the sample number of each sample, the position information of the sample holding section of the sample rack in which the sample having this sample number exists, and the inspection item to be performed on the sample having the sample number, The position of the sample having the sample number on the sample rack can be known from the sample number, and dispensing based on the inspection item to be performed on the sample can be performed.

[Brief description of drawings]

FIG. 1 is a diagram for explaining a sample inspection processing step in a sample laboratory.

FIG. 2 is a diagram for explaining a flow of a sample, a test request form, and test information in a sample receiving step.

FIG. 3 is a flowchart for explaining an outline of a dispensing process.

FIG. 4 is a diagram for explaining a layout of a dispensing system installation room in which a sample dispensing system is installed.

FIG. 5 is a diagram for explaining details of a dispensing area.

FIG. 6 is a diagram for explaining a configuration of a computer that controls a sample receiving step.

FIG. 7 is a block diagram showing the configuration of an unpacking process management computer.

FIG. 8 is a block diagram showing the configuration of a batch assembly process management computer.

FIG. 9 is a block diagram showing a configuration of an input process management computer.

FIG. 10 is a block diagram showing a configuration of a large-scale sorting process management computer.

FIG. 11 is a block diagram showing a configuration of a sorting process management computer.

FIG. 12 is a block diagram showing the configuration of a freeze-free sorting process management computer.

FIG. 13 is a block diagram illustrating a configuration of a computer system that controls a sample dispensing process.

FIG. 14 is a block diagram showing the configuration of a dispensing preprocessing management computer.

FIG. 15 is a block diagram showing the configuration of a rack assembly apparatus management computer.

FIG. 16 is a block diagram showing the configuration of a rack loading device management computer.

FIG. 17 is a block diagram showing the configuration of a rack pull-in device management computer.

FIG. 18 is a block diagram showing the configuration of a dispensing processing unit management computer.

FIG. 19 is a block diagram showing the configuration of a rack ejection device management computer.

FIG. 20 is a flow chart for explaining the processing of the unpacking process.

FIG. 21 is a diagram for explaining the process of the unpacking process.

FIG. 22 is a diagram for explaining data stored in the storage unit of the unpacking process management computer.

FIG. 23 is a flowchart for explaining a process of a batch assembly process.

FIG. 24 is a diagram for explaining the process of the batch assembly process.

FIG. 25 is a diagram for explaining data stored in the storage unit of the batch assembly process management computer.

FIG. 26 is a flowchart for explaining processing of an input step.

FIG. 27 is a diagram for explaining data stored in the storage unit of the input process management computer.

FIG. 28 is a perspective view of a sample rack used in a sample receiving step.

FIG. 29 is a cross-sectional view of a sample rack used in a sample receiving step.

FIG. 30 is a diagram for explaining data stored in a storage unit of a core host computer.

FIG. 31 is a diagram for explaining data stored in the storage unit of the large-scale sorting process management computer.

FIG. 32 is a flowchart for explaining a process of a large-scale sorting process.

FIG. 33 is a schematic diagram for explaining a large sorting device.

FIG. 34 is a flowchart for explaining a process of a sorting process.

FIG. 35 is a schematic diagram for explaining an arrangement state of a sorting device.

FIG. 36 is a schematic diagram for explaining a configuration of a sorting device.

FIG. 37 is a flowchart for explaining a frozen-free sorting process.

[Fig. 38] Fig. 38 is a schematic diagram for explaining the configuration of an ice-freezing sorting apparatus.

FIG. 39 is a perspective view of a sample rack with BC.

FIG. 40 is a perspective view of a sample rack with BC.

FIG. 41 is a flowchart for explaining pre-dispensing processing.

FIG. 42 is a diagram for explaining sample information for each sample stored in the backbone host computer.

FIG. 43 is a diagram for describing the dispensing information stored in the dispensing host computer at the start of rack assembly processing.

FIG. 44 is a flowchart for explaining rack assembly processing.

FIG. 45 is a schematic diagram for explaining rack assembly processing.

FIG. 46 is a diagram for explaining the dispensing information stored in the dispensing host computer at the end of the rack assembly process.

FIG. 47 is a flowchart for explaining a dispensing line process.

FIG. 48 is a flowchart for explaining DC writing.

FIG. 49 is a schematic diagram for explaining DC writing.

[Fig. 50] Fig. 50 is a diagram for explaining a transport route of a sample rack with BC in a dispensing area.

[Fig. 51] Fig. 51 is a diagram for explaining the transport path of the BC-equipped sample rack in the dispensing area.

FIG. 52 is a flow chart for explaining how the sample rack with BC is pulled into the volume determination dispensing unit.

FIG. 53 is a flowchart for explaining the volume determination dispensing in the volume determination dispensing unit.

FIG. 54 is a view for explaining the volume determination dispensing in the volume determination dispensing unit.

FIG. 55 is a flowchart for explaining how to draw the BC-equipped sample rack into the section dispensing unit.

FIG. 56 is a flowchart for explaining section dispensing in a section dispensing unit.

FIG. 57 is a diagram for explaining section dispensing in a section dispensing unit.

FIG. 58 is a diagram for explaining information stored in a dispensing host computer in correspondence with a sample number after section dispensing.

FIG. 59 is a flow chart for explaining supply of a sub sample rack.

[Fig. 60] Fig. 60 is a diagram for explaining supply of a sub-sample rack.

FIG. 61 is a flowchart for explaining how to draw the BC-equipped sample rack into the pre-dispensing unit.

FIG. 62 is a flowchart for explaining pre-dispensing in the pre-dispensing unit.

FIG. 63 is a view for explaining pre-dispensing in the pre-dispensing unit.

FIG. 64 is a diagram for explaining information stored in a dispensing host computer after pre-dispensing in association with a sample number.

FIG. 65 is a flowchart for explaining a sample storage process.

FIG. 66 is a diagram for explaining a sample storage process.

[Explanation of symbols]

A ... acceptance process, B ... dispensing process, C ... measurement process, D ... report preparation process, A1 ... unpacking process, A2 ... batch assembly process, A3
... input process, A4 ... large sort process, A5 ... sort process, A6 ... frozen-free sort process, A7 ... specimen dispensing system installation room carry-in process, B1 ... carry-in processing process, B2 ... retest preparation process, B3 ... dispense Pretreatment process, B4 ... Rack assembly treatment process, B5 ... Dispensing line treatment process, B6 ... Holding treatment process,
B7 ... Carrying out process step, 1 ... Core host computer, 2
... reception host computer, 3 ... unpacking process management computer, 4 ... batch assembly process management computer, 5 ... input process management computer, 6 ... large sorting process management computer, 6b ... bar code reader (first detection means), 6
c ... Storage unit (sorting information storage means), 6f ... Data carrier writer (sorting information writing means), 7 ... Sorting process management computer, 8 ... Defrosted sorting process management computer, 16 ... Dispensing host computer, 17 ... Minutes Pretreatment management computer, 18 ... Rack assembly device management computer, 18d ... Self-propelled BCR (second detection means), 19 ...
Rack loading device management computer, 19b ... Data carrier reader / writer (dispensing information writing means), 20 ... Rack pulling device management computer, 21 ... Dispensing unit management computer, 22 ... Rack ejection device management computer, 40 ... Sample box, 42 ... Specimen, 43 ... Examination request form, 44 ... Storage shelf, 45 ... Specimen rack (sorting specimen rack), 46 ... Data carrier (DC), 47 ... BOX
Input management form, 48 ... Batch input management form, 52 ... Large sorting device, 54 ... Sorting device (sample sorting means), 25 ...
Sample dispensing system installation room, 28 ... Dispensing pretreatment process area, 28c ... Dispensing pretreatment work table, 29 ... Rack assembly process area, 29a ... Rack assembly device, 31 ... Dispensing area, 3
1c ... Section dispensing unit (dispensing means), 31d ...
Pre-dispensing unit (dispensing means), 68 ... BC-equipped sample rack (sample rack), 69 ... Data carrier (DC), 8
8 ... Child sample rack.

Claims (9)

[Claims] 1. A sample sorting unit that sorts samples based on sample sorting information, and a plurality of sample holding units that hold the samples sorted by the sample sorting unit, and each sample held by these sample holding units Of the sample rack having a storage medium for storing the dispensing information of the sample and whether or not the sample requiring dispensing is stored in the sample rack by reading the dispensing information from the storage medium of the sample rack Specimen collection characterized by comprising: a discriminating means, and a dispensing means that dispenses the specimen based on the dispensing information when it is discriminated by the discriminating means that a specimen requiring dispensing exists. Distribution system. 2. The sample sorting means has a sample holding section, and has a storage medium for storing sorting information of samples held by the sample holding section; and a storage medium of the sorting sample rack. 2. The sample sorting apparatus according to claim 1, further comprising sorting information reading means for reading sorting information from the sorting information and sorting destination determining means for determining sorting destinations based on the read sorting information. Distribution system. 3. The sorting information includes an inspection item to be performed on the sample held in the sample holding section of the sorting sample rack. The sample preparative distribution system described. 4. The dispensing information includes a sample number for each sample,
3. The position information of the sample holding unit of the sample rack in which the sample having the sample number is present and the inspection item to be performed on the sample having the sample number are included. Sample distribution system. 5. A sorting information storage unit for storing sorting information for each sample, a first detecting unit for detecting the sample contained in the sorting sample rack, and a detection unit for detecting the sample. The sorting information writing unit for reading the sorting information for the sample from the sorting information storage unit and writing the sorting information in a storage medium included in the sorting sample rack is included in any one of claims 1 to 4. The sample preparative distribution system described in. 6. A dispensing information storage unit for storing dispensing information for each sample, a second detecting unit for detecting the sample contained in the sample rack, and a second detecting unit for detecting the sample. 5. The dispensing information writing means for reading the dispensing information for the specimen from the dispensing information storage means and writing the information in the storage medium of the specimen rack, according to any one of claims 1 to 4. The sample preparative distribution system according to the item. 7. The sample dispensing / distributing system according to claim 6, further comprising a dispensing result writing unit for writing the dispensing result of the sample by the dispensing unit into a storage medium included in the sample rack. . 8. The sample dispensing / distributing system according to claim 7, wherein the dispensing result writing means further writes the dispensing result to the dispensing information storage means. 9. The sample dispenser according to claim 7 or 8, wherein the dispensing result includes position information of a sample holder in a slave sample rack that holds the dispensed slave sample. Distribution system.