JPH0225170Y2 - - Google Patents

Description

[Detailed description of the invention] Industrial application field The present invention is an improved method that makes it easy to check whether the test piece has been reliably immersed in the liquid to be tested when testing components in liquids such as urine tests. This relates to a test piece for liquid testing.

BACKGROUND OF THE INVENTION Various types of test pieces are known for detecting predetermined components in liquids. Taking a urine test as an example, urine, which is the liquid to be tested, contains various components, and even in a regular medical checkup, the protein and sugar content in the urine and the hydrogen ion concentration index (PH) are measured. ) is highly significant as a preliminary check. In order to detect each of these components or to confirm that the level is above (or below) a certain standard, a reagent selected for each component is absorbed into a filter paper, etc., and then attached to a suitable substrate. Test pieces made in this manner are already known.

Problems that the invention aims to solve However, conventional test pieces are immersed in a test liquid, such as urine, then pulled out, and after a certain period of time, the change in hue of the test reagent area is checked against a standard color table. However, when a large number of tests are carried out at once, such as in group medical examinations for companies and organizations, it is possible that the test piece is not immersed in the test liquid to a sufficient depth, or that the test piece is forgotten to be immersed. Although it is possible, it has been difficult to directly confirm whether or not immersion has been completed.
For this reason, in tests using test strips, incorrect judgments may be made, or if only a portion of the test reagent area is immersed, unevenness may occur in the changed hue, which may impede judgment.

Particularly in recent years, as the number of items tested using a single test piece has increased, the test reagent area has been formed to cover a large percentage of the length of the test piece (usually a long shape such as a rod or strip). There are often
This becomes a problem when the amount of liquid to be tested is small.

Therefore, the present invention aims to make it possible to reliably determine the immersion situation with the naked eye, which cannot be confirmed with the conventional test piece described above.

Means for Solving the Problems In order to achieve the above-mentioned purpose, the present invention has a test piece in which, in addition to the usual test reagent part, a region that changes in hue upon contact with the solvent in the test liquid is formed on the test piece. It is something. That is, the present invention has at least one test reagent part in a part of the base body, and a part that is above the test reagent part when immersed in the test liquid, and has a solvent in the test liquid. This test piece is characterized by having an immersion confirmation reagent part containing a reagent that causes a hue change upon contact with the liquid.

FIG. 1 is a plan view showing an example of the present invention, in which a test piece 1 for liquid testing has three test reagent parts 3, 4, and 5 on one side of a base 2, and
An immersion confirmation reagent section 6 is provided on the same surface on the right side of the three test reagent sections in the figure.

In the above, ordinary materials can be used as the substrate 2, such as (a) polyethylene terephthalate,
Sheets of plastic such as polystyrene or polyvinyl chloride, (b) Non-woven fabrics of chemical fibers such as polyester, polypropylene or nylon, (c)
Paper such as filter paper, art paper, or coated paper can be used.

In addition, in the above, the test reagent section refers to, for example, the test reagent section 3 is the glucose test reagent area, and the test reagent section 4 is the glucose test reagent area.
is the protein test reagent section, and the test reagent section 5 is the PH test reagent section. The number of test reagent parts may be increased or decreased depending on the purpose. These test reagent parts are made by pasting filter paper impregnated with a test reagent selected according to the component to be tested using adhesive means such as double-sided tape, or by printing or coating using ink containing such a test reagent. It can be formed by

The reagent part 6 for immersion confirmation, which is the key point of the present invention, contains a reagent that causes a change in color upon contact with the solvent in the liquid to be tested. The solvent in the liquid to be tested is
For example, when the liquid to be tested is urine, it is water, and depending on the liquid to be tested, it may be something other than water, but it is usually water. Therefore,
Causes a hue change on contact with water. Metal salts, preferably copper sulfate (anhydrous), cobalt chloride (monohydrate)
It is preferable to use cobalt chloride (monohydrate) as a reagent, and more preferably cobalt chloride (monohydrate).

To form the immersion confirmation reagent part 6 using the metal salt (described above), the metal salt is dissolved in an organic solvent such as alcohol, water, or a water/organic solvent mixed solution and applied to an absorbent carrier such as a filter paper. by impregnation or printing or coating in a paste or ink with a metal salt together with binders, fillers, solvents and/or diluents;
This can be done in the same manner as the formation of test reagent parts 3, 4, and 5. Note that by increasing the proportion of binder, the moisture detection sensitivity is lowered so that a hue change occurs only when it comes into contact with a large amount of water (in other words, when it is sufficiently immersed). You can also do it. The same thing can be done by controlling the degree of hydrophobicity of the binder.

The basic structure of the present invention has been explained above.
If the reagent part for immersion confirmation is formed not only in one place as shown in Figure 1, but also between each test reagent part, it will be possible to confirm immersion more reliably. A similar effect can be expected even if the sample is surrounded by a reagent part for immersion confirmation. However, most commonly, the test reagent part is formed on a stick-shaped or strip-shaped base, and such a test piece is pinched vertically and immersed in the liquid to be tested.
When immersing, it is often sufficient to form a reagent part for immersion confirmation at one location on either the front or back of the substrate above any of the test reagent parts.

Function/Effect The test piece for liquid testing of the present invention has a reagent part for immersion confirmation in addition to the test reagent part, so it is easy to check whether it has been immersed in the liquid to be tested. There are no problems caused by only partial implementation.

Example 1 Impregnating liquid composition CoCl ₂ H ₂ O 0.5 parts by weight Ethyl alcohol 89.5 Butyral resin 9.5 (Sekisui Chemical Co., Ltd., BL-2) Filter paper (Toyo Roshi Co., Ltd., No. 51)
After impregnation, the sample was dried at 70°C for 20 minutes and then cut into a predetermined size to obtain a water detection piece.

The obtained water detection piece was placed on the side opposite to the side where the test area was formed of the 4-item urine test piece (the items are PH, glucose, protein, and occult blood) made of a polystyrene sheet (Fig. 1). 6) with double-sided tape.

The test piece prepared in this way is immersed in the liquid to be tested with the side with the test area (corresponding to 3, 4, and 5 in Figure 1) facing downward, so that it is immersed up to the position of the water detection piece. Since the water detection strip was used as a water detector, it was easy to check whether it had been immersed or not by the color change (from blue to pink).

Example 2 A water detection area was formed by silk screen printing using a paste having the composition below at the position corresponding to 6 in FIG. 1 of the same four-item urine test strip used in Example 1.

Paste composition Cobalt chloride adsorption silica gel powder 30 parts by weight (Fuji Davison, Fujigel Blue) Polyvinyl butyral resin 12 (Sekisui Chemical Co., Ltd., BX-1) Butyl cellosolve 52 The test piece obtained in Example 2 was also tested. It could be used in the same manner as the test piece obtained in Example 1, and the same effects could be obtained.

[Brief explanation of the drawing]

FIG. 1 is a plan view showing an example of the present invention. 1... Test piece, 2... Substrate, 3, 4, 5... Inspection reagent part, 6... Reagent part for immersion confirmation.

Claims (1)

[Scope of utility model registration request] A part of the base body has at least one test reagent part, and a part above the test reagent part when immersed in the test liquid undergoes a hue change upon contact with the solvent in the test liquid. 1. A test piece for liquid testing, characterized by having a reagent part for immersion confirmation containing a reagent to be produced.