JPH02121675A - Probe for hyperthermia - Google Patents

Probe for hyperthermia

Info

Publication number
JPH02121675A
JPH02121675A JP27563288A JP27563288A JPH02121675A JP H02121675 A JPH02121675 A JP H02121675A JP 27563288 A JP27563288 A JP 27563288A JP 27563288 A JP27563288 A JP 27563288A JP H02121675 A JPH02121675 A JP H02121675A
Authority
JP
Japan
Prior art keywords
probe
sheath
needle
prostate
balloon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP27563288A
Other languages
Japanese (ja)
Other versions
JP2619941B2 (en
Inventor
Makoto Inaba
誠 稲葉
Koichiro Ishihara
石原　康一郎
Takashi Tsukatani
塚谷　隆志
Shinji Hatta
信二 八田
Eiichi Fuse
栄一 布施
Masaaki Hayashi
正明 林
Shinichi Nishigaki
西垣　晋一
Hitoshi Karasawa
均 唐沢
Tatsuya Saito
達也 斉藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Optical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Optical Co Ltd filed Critical Olympus Optical Co Ltd
Priority to JP63275632A priority Critical patent/JP2619941B2/en
Publication of JPH02121675A publication Critical patent/JPH02121675A/en
Application granted granted Critical
Publication of JP2619941B2 publication Critical patent/JP2619941B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/1432—Needle curved

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

PURPOSE:To heat a region to be heated uniformly, effectively and certainly as a whole by inserting a probe main body in the body cavity and exposing each needle like electrode to thrust the same in the region to be heated to heat said region. CONSTITUTION:In such a state that the balloon 4 of a probe 1 is contracted, a catheter 3, each needle like electrode 5 and a temperature-sensitive element part 13 are also drawn in the sheath 2 of the probe 1. The sheath 2 is inserted in the urethra 17 and the leading end part of the sheath is applied to the thickened prostate 18 (affected part) and contracted to expose the balloon 4, each needle like electrode 5 and the temperature-sensitive element part 13 from the leading end of the sheath 2 as shown by Fig 3. Then, each needle like electrode 5 having a bending habit curving outwardly is thrust in the thickened prostate 18 and the temp.-sensitive element part 13 is applied to or inserted in the surface part of the prostate. Air is sent to the balloon 4 to inflate the same. The balloon 3 is inflated in a state applied to the wall surface on the bladder 19 present at a deep part of the thickened prostate 18 to be stopped and the probe 1 is fixed.

Description

【発明の詳細な説明】 ［産業上の利用分野コ 本発明は例えば前立腺肥大部等を温熱治療する。Ｈ熱治
療用プローブに関する。DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Fields] The present invention provides thermal treatment for, for example, prostatic hypertrophy. This invention relates to a probe for H heat treatment.

［従来の技術］ 近年、前立腺肥大症の治療を温熱で行なう方法から゛え
られている。これは前立腺を４３°Ｃ前後で加温すると
、その前立腺肥大症が冶癒することを利用するものであ
る。[Prior Art] In recent years, methods of treating benign prostatic hyperplasia using heat have been developed. This takes advantage of the fact that when the prostate is heated to around 43°C, the enlarged prostate is cured.

そして、従来は周囲にマイクロ波用アンテナを設けたカ
テーテルを尿道に挿入してそのアンテナからマイクロ波
を照射し、加温治療していた。Conventionally, a catheter with a microwave antenna around it was inserted into the urethra and microwaves were irradiated from the antenna to perform heating treatment.

また、特開昭６２−２９２１７３号公報で知れるように
チューブ体の中間一部の外周に金属バイブなどの導電体
を設け、これにより加温用電界を集中させるようにした
ものが提案されている。Furthermore, as known from Japanese Patent Application Laid-Open No. 62-292173, it has been proposed to provide a conductor such as a metal vibrator on the outer periphery of the middle part of the tube body, thereby concentrating the electric field for heating. .

［発明が解決しようとする課題］ しかしながら、上記加温方式はいずれも被加温対象の部
位、たとえば前立腺の表面にまたはその近傍に、マイク
ロ波用アンテナまたは加温用電極を設置するのみである
から、その前立腺等の患部を全体的に均一に加温するこ
とはできない。また、全体的に確実かつ効率よく加温す
ることができなかった。[Problems to be Solved by the Invention] However, in all of the above heating methods, a microwave antenna or heating electrode is only installed on or near the surface of the area to be heated, for example, the prostate. Therefore, it is not possible to uniformly heat the entire affected area, such as the prostate gland. Moreover, it was not possible to heat the entire device reliably and efficiently.

本発明は上記課題に着目してなされたもので、その目的
とするところは被加温対象部を全体的に均一で効率よく
確実に加温することができる温熱治療用プローブを提供
することにある。The present invention has been made in view of the above-mentioned problems, and its purpose is to provide a thermotherapy probe that can uniformly, efficiently, and reliably heat the entire area to be heated. be.

［課題を解決するための手段および作用］上記課題を解
決するために本発明の温熱治療用プローブは体腔内に挿
入するプローブ本体と、このプローブ本体内にその先端
から突没自在に設すられ露出して被加温対象部位に刺通
する複数の加温用針状電極と、この針状電極を露出する
操作手段とからなり、プローブ本体を体腔内に挿入し、
その各針状電極を露出し被加温対象部位に刺通して加温
するようにしたものである。[Means and effects for solving the problems] In order to solve the above problems, the thermotherapy probe of the present invention includes a probe body to be inserted into a body cavity, and a probe body that is installed in the probe body so as to be able to protrude and retract from its tip. It consists of a plurality of heating needle-like electrodes that are exposed and pierced through the target area to be heated, and an operation means that exposes the needle-like electrodes, and the probe body is inserted into the body cavity,
Each of the needle-like electrodes is exposed and pierced into the target area to be heated.

このように複数の針状電極を被加温対象部位に刺通して
加温するようにしたから、被加温対象部位を全体的に均
一で効率よく確実に加温することができる。Since the plurality of needle-like electrodes are inserted into the target region to heat the region, the region to be heated can be heated uniformly, efficiently, and reliably as a whole.

［実施例］ 第１図ないし第３図は本発明の第１の実施例を示すもの
である。この実施例は前立腺肥大症を治療するためのも
のである。第１図で示すようにその温熱治療用プローブ
１は体腔内に挿入するプローブ本体として可撓性のシー
ス２を有し、このシース２内にはカテーテル３が挿通さ
れている。[Embodiment] FIGS. 1 to 3 show a first embodiment of the present invention. This example is for treating benign prostatic hyperplasia. As shown in FIG. 1, the thermotherapy probe 1 has a flexible sheath 2 as a probe body to be inserted into a body cavity, and a catheter 3 is inserted into the sheath 2.

このカテーテル３の先端部分はそのシース２の先端開口
から突き出せるように設けられている。カテーテル３の
先端にはゴムで形成したバルーン４が設けられている。The distal end portion of the catheter 3 is provided so as to protrude from the distal opening of the sheath 2. A balloon 4 made of rubber is provided at the tip of the catheter 3.

このカテーテル３は可撓性で、その内部には軸方向に沿
う流体供給用孔（図示しない。）が形成されていて、こ
れは上記バルーン４に連通されている。そして、バルー
ン４は通常収縮しているが、上記流体供給用孔より供給
される流体によって第１図で示すように膨張するように
なっている。This catheter 3 is flexible and has a fluid supply hole (not shown) formed in its interior along the axial direction, which communicates with the balloon 4. The balloon 4 is normally deflated, but is expanded as shown in FIG. 1 by the fluid supplied from the fluid supply hole.

また、上記シース２の先端部にはそれぞれ外側に曲がり
癖のある複数の針状電極５がそのシース２の先端開口か
ら突没自在に設けられている。この各針状電極５はシー
ス２の内部に挿入した図示しない操作ワイヤの先端に連
結され、この操作ワイヤは手元側に設けた操作手段の操
作ハンドル６により進退操作されるようになっている。Further, a plurality of needle-like electrodes 5 each having a tendency to bend outward are provided at the distal end of the sheath 2 so as to be protruding and retractable from the distal opening of the sheath 2. Each of the needle electrodes 5 is connected to the tip of an operating wire (not shown) inserted into the sheath 2, and the operating wire is moved forward and backward by an operating handle 6 of operating means provided on the proximal side.

操作ハンドル６は第２図で示すように上記シース２の手
元側基端に設けたシース保持部材７に対して進退自在に
装管されている。また、この操作ハンドル６には上記針
状電極５に導通する接続端子８が設けられ、この接続端
子８にはマイクロ波伝送用ケブル９を介してマイクロ波
発生装置１０に接続されるようになっている。さらに、
操作ハンドル６には上記カテーテル３に通じる口金１１
が設けられている。As shown in FIG. 2, the operating handle 6 is attached to a sheath holding member 7 provided at the proximal end of the sheath 2 so as to be able to move forward and backward. Further, this operating handle 6 is provided with a connecting terminal 8 that is electrically connected to the needle-shaped electrode 5, and this connecting terminal 8 is connected to a microwave generator 10 via a microwave transmission cable 9. ing. moreover,
The operating handle 6 has a cap 11 that communicates with the catheter 3.
is provided.

また、上記シース２の先端部には複数の針状電極５とと
もにそのシース２の先端開口から突没自在な感温素子部
１３が設けられている。この感温素子部１３はたとえば
熱雷対からなり、これに通じるｄＰＩ　？Ｈケーブル１
４はシース２の内部を通じて外部に設置される？Ｈ度計
１５に接続されるようになっている。この温度計１５の
４−１温データは上記マイクロ波発生装置１０を制御す
るコントロールユニット１６に接続されている。Further, at the distal end of the sheath 2, a plurality of needle electrodes 5 and a temperature sensing element portion 13 which can be freely protruded and retracted from the distal opening of the sheath 2 are provided. This temperature sensing element section 13 is made up of, for example, a thermal lightning pair, and the dPI? H cable 1
4 is installed externally through the inside of sheath 2? It is designed to be connected to an H degree meter 15. 4-1 temperature data from this thermometer 15 is connected to a control unit 16 that controls the microwave generator 10.

次に、このように構成された混熱治療システムの使用方
法を説明する。まず、プローブ１のバルーン４を収縮さ
せた状態で、ハンドル６を手元側に後退させる。これに
よりカテーテル３とともにバルーン４はシース２内に引
き込まれる。また、各針状電極５および感温素子部１３
もそのシース２内に引き込まれる。Next, a method of using the mixed heat treatment system configured as described above will be explained. First, with the balloon 4 of the probe 1 deflated, the handle 6 is retreated toward the user's hand. As a result, the balloon 4 and the catheter 3 are drawn into the sheath 2. In addition, each needle electrode 5 and the temperature sensing element part 13
is also drawn into the sheath 2.

そこで、このシース２を尿道１７に挿入し、シース２の
先端部を肥大した前立腺１８（患部）のところに位置さ
せる。そして、シース２を後退させることにより第３図
で示すようにバルーン４、各針状電極５および感温素子
部１３がそのシース２の先端から露出する。Therefore, this sheath 2 is inserted into the urethra 17, and the distal end of the sheath 2 is positioned at the enlarged prostate 18 (affected area). Then, by retracting the sheath 2, the balloon 4, each needle electrode 5, and the temperature sensing element portion 13 are exposed from the tip of the sheath 2, as shown in FIG.

そして、外側に湾曲する曲がり癖のある各針状電極５を
肥大した前立腺１８にそれぞれ突き刺す。Then, each needle electrode 5, which has a tendency to curve outward, is inserted into the enlarged prostate 18, respectively.

感温素子部１３は前立腺１８の表面部に当てまたは刺通
させる。また、バルーン３に送気してこれを膨張させる
。これによりバルーン３は肥大した前立腺１８の奥にあ
る膀胱１９側の壁面に当る状態で膨張して係止し、プロ
ーブ１を固定する。The temperature sensing element section 13 is applied to or penetrates the surface of the prostate gland 18. Also, air is supplied to the balloon 3 to inflate it. As a result, the balloon 3 inflates and locks against the wall of the bladder 19 located deep inside the enlarged prostate 18, thereby fixing the probe 1.

ついて、前立腺１８の温度を温度計１５で測定し始める
とともに、マイクロ波発生装置１０を作動してマイクロ
波伝送用ケーブル９を通じてマイクロ波エネルギを上記
各針状電極５に供給し、マイクロ波を出射してその前立
腺１８を加温する。Then, the temperature of the prostate gland 18 is started to be measured with the thermometer 15, and the microwave generator 10 is activated to supply microwave energy to each of the needle electrodes 5 through the microwave transmission cable 9 to emit microwaves. The prostate gland 18 is then heated.

このとき、加温される前立腺１８の温度は上記温度計１
５で測定され、その温度が４３°Ｃ（例えば４２°Ｃ〜
４５°Ｃ）前後になるようにコントロールユニット１６
によりマイクロ波の出力を制御する。At this time, the temperature of the heated prostate 18 is measured by the thermometer 1.
5 and the temperature is 43°C (e.g. 42°C ~
Control unit 16 so that the temperature is around 45°C).
to control the microwave output.

しかして、上記患部の前立腺１８はこれに刺通された針
状電極５によってその内部から加温され、全体的に均一
に加温できる。Thus, the affected prostate 18 is heated from within by the needle-like electrode 5 pierced through it, and can be heated uniformly as a whole.

なお、上記カテーテル３を先端まで突き抜ける中空なも
のとし、これにプローブの挿入を補助するガイドワイヤ
を挿通できるようにしてもよい。Incidentally, the catheter 3 may be made hollow so that it can be penetrated to the tip, and a guide wire for assisting insertion of the probe may be inserted through the catheter 3.

第４図および第５図は本発明の第２の実施例を示すもの
である。この実施例は針状電極５の少なくとも１本のも
のを第５図で示すように中空状に形成し、この中空部２
０内に熱電対からなる感温素子部〕３を挿通して設けた
ものである。これによれば、針状電極５とともに感温素
子部１３を患部内に刺通できる。このため、より正確に
温度を、則定することができる。4 and 5 show a second embodiment of the present invention. In this embodiment, at least one of the needle electrodes 5 is formed into a hollow shape as shown in FIG.
A temperature-sensing element part] 3 consisting of a thermocouple is inserted into the inside of the thermocouple. According to this, it is possible to pierce the temperature sensing element portion 13 together with the needle electrode 5 into the affected area. Therefore, the temperature can be determined more accurately.

なお、本発明は上記各実施例のものに限定されるもので
はない。その要旨を超脱しない範囲で種々の変形が可能
である。また、使用する治療対象は前立腺に限らない。Note that the present invention is not limited to the above embodiments. Various modifications are possible without departing from the gist of the invention. Furthermore, the therapeutic target to be used is not limited to the prostate.

また、上記針状電極を２本で一対とする高周波用電極と
して構成し、その電極間に高周波エネルギを供給して通
電加熱する方式としたものでもよい。Alternatively, the needle-like electrodes may be configured as a pair of high-frequency electrodes, and high-frequency energy may be supplied between the electrodes to conduct electrical heating.

［発明の効果］ 以上説明したように本発明の体腔内患部の温熱治療用プ
ローブは複数の針状電画を被加温対象部位に刺通して加
温するようにしたから、被加温対象部位を全体的に均一
で効率よく確実に加温することができる。[Effects of the Invention] As explained above, since the probe for thermotherapy of an affected area in a body cavity of the present invention is configured to heat a target area to be heated by piercing a plurality of needle-like electromagnets into the target area to be heated, can be heated uniformly, efficiently, and reliably throughout.

【図面の簡単な説明】[Brief explanation of drawings]

第１図は本発明の第１の実施例を示す温熱治療用プロー
ブの側断面図、第２図は同じくその第１の実施例の温熱
治療システムを含めた１、１４成説明図、第３図は同じ
くその第１の実施例の温熱治療システムの使用説明図、
第４図は本発明の第２の実施例を示す温熱治療用プロー
ブの先端付近の側面図、第５図は同じくその第２の実施
例における針状電極の先端部の側断面図である。 １・ｉ’Ｒ熱治療治療ローブ、２・・・シース、５・・
・針状電極、６−・・操作ハンドル、７・・・シース保
持部材、１８・・・前立腺。FIG. 1 is a side sectional view of a thermotherapy probe showing a first embodiment of the present invention, FIG. The figure is also an explanatory diagram of the use of the thermotherapy system of the first embodiment,
FIG. 4 is a side view of the vicinity of the tip of a thermotherapy probe showing a second embodiment of the present invention, and FIG. 5 is a side sectional view of the tip of a needle electrode in the second embodiment. 1. i'R heat treatment treatment robe, 2... sheath, 5...
- Needle electrode, 6--operation handle, 7--sheath holding member, 18--prostate.

Claims (1)

【特許請求の範囲】[Claims] 体腔内の患部を温熱治療する温熱治療用プローブにおい
て、体腔内に挿入するプローブ本体と、このプローブ本
体内にその先端から突没自在に設けられ露出して被加温
対象部位に刺通する複数の加温用針状電極と、この針状
電極を露出する操作手段とからなり、プローブ本体を体
腔内に挿入し、その各針状電極を露出し被加温対象部位
に刺通して加温するようにしたことを特徴とする温熱治
療用プローブ。A thermotherapy probe that performs heat treatment on an affected area within a body cavity includes a probe body that is inserted into the body cavity, and a plurality of probes that are provided within the probe body so as to be able to protrude and retract from its tip and that are exposed and pierce the target area to be heated. The probe body is inserted into the body cavity, and each of the needle electrodes is exposed and pierced into the target area to be heated. A thermotherapy probe characterized by:
JP63275632A 1988-10-31 1988-10-31 Hyperthermia probe Expired - Lifetime JP2619941B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP63275632A JP2619941B2 (en) 1988-10-31 1988-10-31 Hyperthermia probe

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63275632A JP2619941B2 (en) 1988-10-31 1988-10-31 Hyperthermia probe

Publications (2)

Publication Number Publication Date
JPH02121675A true JPH02121675A (en) 1990-05-09
JP2619941B2 JP2619941B2 (en) 1997-06-11

Family

ID=17558165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63275632A Expired - Lifetime JP2619941B2 (en) 1988-10-31 1988-10-31 Hyperthermia probe

Country Status (1)

Country Link
JP (1) JP2619941B2 (en)

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017856A1 (en) * 1993-02-02 1994-08-18 Vidamed, Inc. Transurethral needle ablation device and method
WO1994026187A1 (en) * 1993-05-13 1994-11-24 Vidamed, Inc. Medical probe device with optic viewing capability
WO1995017132A1 (en) * 1993-12-22 1995-06-29 Vidamed, Inc. Medical probe apparatus with laser and/or microwave monolithic integrated circuit probe
WO1995018575A1 (en) * 1994-01-06 1995-07-13 Vidamed, Inc. Medical probe apparatus with enhanced rf, resistance heating, and microwave ablation capabilities
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US5667488A (en) * 1992-08-12 1997-09-16 Vidamed, Inc. Transurethral needle ablation device and method for the treatment of the prostate
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US5458597A (en) * 1993-11-08 1995-10-17 Zomed International Device for treating cancer and non-malignant tumors and methods
US5472441A (en) * 1993-11-08 1995-12-05 Zomed International Device for treating cancer and non-malignant tumors and methods
WO1995017132A1 (en) * 1993-12-22 1995-06-29 Vidamed, Inc. Medical probe apparatus with laser and/or microwave monolithic integrated circuit probe
WO1995018575A1 (en) * 1994-01-06 1995-07-13 Vidamed, Inc. Medical probe apparatus with enhanced rf, resistance heating, and microwave ablation capabilities
FR2716365A1 (en) * 1994-02-02 1995-08-25 Vidamed Inc Transurethral needle ablation device, equipped with a cystoscope.
US5469524A (en) * 1994-05-12 1995-11-21 Indigo Medical, Incorporated Fiberoptic delivery system and method of use
USRE36473E (en) * 1994-05-12 1999-12-28 Indigo Medical, Inc. Fiberoptic delivery system and method of use
WO1996016606A1 (en) * 1994-12-01 1996-06-06 Vidamed, Inc. Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
US5588960A (en) * 1994-12-01 1996-12-31 Vidamed, Inc. Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
WO1996022742A1 (en) * 1995-01-25 1996-08-01 Vidamed, Inc. Transurethral needle ablation device and method for the treatment of the prostate
EP1576932A1 (en) * 1995-03-24 2005-09-21 Board Of Regents Of The University Of Nebraska Apparatus for ablation of tissue masses
USRE38299E1 (en) 1995-05-18 2003-11-11 Prostalund Operations Ab Apparatus for heat treatment of tissue
US6077261A (en) * 1995-06-07 2000-06-20 Radiotherapeutics Corporation Device for permanent vessel occlusion
US5709224A (en) * 1995-06-07 1998-01-20 Radiotherapeutics Corporation Method and device for permanent vessel occlusion
US8753366B2 (en) 1995-10-13 2014-06-17 Medtronic Vascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US7648517B2 (en) 1995-10-13 2010-01-19 Medtronic Vascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US6656173B1 (en) 1996-02-22 2003-12-02 Radio Therapeutics Corporation Method and device for enhancing vessel occlusion
US6270495B1 (en) 1996-02-22 2001-08-07 Radiotherapeutics Corporation Method and device for enhancing vessel occlusion
US6016452A (en) * 1996-03-19 2000-01-18 Kasevich; Raymond S. Dynamic heating method and radio frequency thermal treatment
EP1820436A3 (en) * 1997-04-11 2007-11-14 Medtronic Vascular, Inc. Catheters and related devices for forming passagways between blood vessels or other anatomical structures
EP1820436A2 (en) * 1997-04-11 2007-08-22 Medtronic Vascular, Inc. Catheters and related devices for forming passagways between blood vessels or other anatomical structures
FR2766721A1 (en) 1997-08-01 1999-02-05 Technomed Medical Systems INTRACORPOREAL PROBE COMPRISING AN INTERSTITIAL TEMPERATURE MEASURING DEVICE AND THERAPEUTIC TREATMENT APPARATUS INCLUDING APPLICATION
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US9023031B2 (en) 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
USRE40472E1 (en) 1998-07-28 2008-08-26 Prostalund Operations Ab Method and device for combined heat treatment of body tissue
US8753342B2 (en) 1998-08-05 2014-06-17 Emcision Limited Method of using electrosurgical device for restricting loss of blood during surgery
US6366818B1 (en) 1999-02-04 2002-04-02 Prostalund Operations Ab Method and device for combined heat treatment of body tissue
US6584361B1 (en) 1999-05-07 2003-06-24 Prostalund Operations Ab Method and device for heat treatment of body tissue
US8968284B2 (en) 2000-10-02 2015-03-03 Verathon Inc. Apparatus and methods for treating female urinary incontinence
JP4931032B2 (en) * 2000-10-02 2012-05-16 ノヴァシス メディカル インコーポレイテッド Apparatus and method for treating urinary incontinence in women
JP2004510507A (en) * 2000-10-02 2004-04-08 ノヴァシス　メディカル　インコーポレイテッド Apparatus and method for treating urinary incontinence in women
US6868290B2 (en) 2001-11-05 2005-03-15 Prostalund Operations Ab Thermotherapy catheter and method of prostate thermotherapy with improved guide and heat confinement
WO2005039672A1 (en) * 2003-10-23 2005-05-06 Shinshu Tlo Co., Ltd. Method of increasing viscosity of thickening composition, and needle device
US8147397B1 (en) 2006-05-19 2012-04-03 Carbon Medical Technologies, Inc. Urethral needle guide device

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