JPH01240169A - Concentrated liquid food - Google Patents

Abstract

PURPOSE:To obtain a concentrated liquid food preservable at room temperature for 1 year without causing separation, precipitation and coagulation and keeping good emulsion stability even after sterilization treatment, by increasing the concentration of mineral, especially potassium and using in combination with a chelating agent. CONSTITUTION:A concentrated liquid food is prepared by conventional method using protein or its decomposition product, carbohydrate, lipid, vitamin and mineral as main components. In the above process, the content of potassium mineral is adjusted to 0.07-0.30wt.% and the amount of minerals other than potassium is adjusted to 0.25-1.0wt.% based on the whole composition. In addi tion to the above, a chelating agent such as sodium metaphosphate or sodium pyrophosphate is added in an amount of 0.02-0.15wt.%.

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to a concentrated liquid diet used for the purpose of nutritional supplementation to patients before and after surgery.

(Prior art) Currently, there are two types of concentrated liquid foods used in hospitals, etc.: powder type and liquid type, but liquid type is becoming preferred due to its ease of handling. There is.

Generally, liquid-type products are required to have emulsion stability that can withstand storage at room temperature for several months, tube fluidity that allows the product to pass through a narrow tube in a short time, and good flavor.

However, no liquid type product has been found that contains a large amount of minerals and meets the above conditions.

(Problem to be solved by the invention) On the other hand, the minerals and vitamins contained in conventional concentrated liquid foods have a standard energy content of 1600 kcal to 24 kcal.
00kcal, it is formulated taking into consideration the nutritional requirements of Japanese people.

However, for elderly patients and patients with cerebrovascular disorders, the amount of energy administered should be lower, usually 1000 to 1400.
Cal is being administered. Therefore, when current products are used in these patients, the doses of minerals and vitamins are reduced, making it impossible to meet nutritional requirements.

Minerals and vitamins have various roles in the body to maintain living organisms, and among them, potassium is a major cation present in cells and is one of the important minerals that maintains osmotic pressure inside and outside cells.

Even in patients with decreased gastric acid secretion in the stomach and other patients, the ability to absorb minerals is lower than in general healthy people, and if a conventional concentrated liquid diet is administered□, potassium deficiency may occur. has been pointed out.

Currently, there are powder and liquid types of products as mentioned above, but the powder type needs to be dissolved in warm water before being administered to the patient, so these less labor-intensive liquid types are preferred. It is rare. In the case of a liquid type, if too many minerals are added, the protein will denature and cause aggregation and creaming. That is, with the conventional technology, there was a problem in that it was difficult to produce an emulsified concentrated liquid food that contained a sufficient amount of minerals and was stable over a long period of time.

(Means for Solving the Problems) In order to solve these problems, the present invention provides minerals,
It was found that a very good emulsified concentrated liquid food can be obtained by increasing the concentration of vitamins, especially potassium, and also using a chelating agent, leading to the present invention.

That is, the present invention provides proteins or decomposition products thereof, carbohydrates,
In a concentrated liquid diet whose main ingredients are fat, vitamins, and minerals, the potassium content in the minerals is 0 compared to the total composition.
．． 07 to 0.30% by weight, mineral content other than potassium is 0.25 to 1.0% by weight, and further 0.02 to 0.
．． It is characterized by containing 15% by weight of a chelating agent.

The amount of potassium added is 0.07 to 0.30% by weight in the total composition, and if it is less than 0.07% by weight, its function will not be exhibited, and if it is more than 0.30% by weight, it will adversely affect the human body. Physiological burden increases.

The nutritional requirement for potassium for Japanese people is 2000-4000m
The potassium requirement for adults is 0.4 milliequivalents (15.6 eq. g) per kg of body weight per day.
1g).

The amount of potassium added according to the present invention is such that even when the amount of energy ingested by the patient is 1000 to 1400 kcal/day, the necessary amount of potassium can be sufficiently ingested.

In the present invention, nutritionally necessary minerals are added in addition to potassium. These minerals are mainly sodium, calcium, magnesium, and iron, and their total amount is in the range of 0.25 to 1.0% by weight. Actually,
1000-1400 kc to the patient as well as potassium above
It is designed so that the required amount of minerals can be ingested based on the amount of energy per day.

In the present invention, a chelating agent is added to prevent protein insolubility. The chelating agent used is preferably at least one type selected from condensed phosphates. Specifically, the decalate agents used in the present invention are various sodium phosphates and sodium citrate, preferably sodium italate, sodium acid birophosphate, tetrasodium pyrophosphate, sodium birophosphate, and sodium polyphosphate. , condensed phosphates such as ultraphosphates. The amount of these added is 0.02 to 0 in the total composition.
．． The amount is 15% by weight, but the effect is not exhibited at 0.02% by weight or less, and the effect is sufficiently exhibited up to 0.15% by weight, so no more than 0.02% by weight is required.

The concentrated liquid food of the present invention mainly contains protein or its decomposition products, carbohydrates, lipids, vitamins, and water in addition to minerals, in order to sufficiently supply the nutrients necessary for the human body.

The protein used in the present invention is one that is easily digested and absorbed and has high nutritional value.

Examples include milk protein, soybean protein, fish protein, meat protein, egg protein, gelatin, etc., and enzymatic decomposition products thereof, which can be used alone or in combination of two or more.

The carbohydrates used in the present invention include starch, dextrin, and hydrolysates thereof.

Furthermore, monosaccharides such as glucose and fructose, and trisaccharides such as maltose and lactose can be used singly or in combination of two or more.

The lipids used in the present invention include processed fats and oils such as soybean oil, corn oil, rapeseed oil, coconut oil, lard, beef tallow, and fish oil.

The present invention contains various nutritionally necessary vitamins. The blending amount is such that the patient can fully ingest the nutritionally required amount of various vitamins when the patient's energy amount is 1000 to 1400 Kcal per 7 days.

Further, flavors, fruit juice, etc. may be added as necessary.

The concentrated liquid food of the present invention contains the above proteins and their decomposition products, carbohydrates, lipids, vitamins and minerals in a predetermined amount of heat and
That is, it is manufactured by dissolving it in water to a concentration of I Kcal/ml, performing homogenization using a homogenizer to obtain a uniform emulsion, and then performing high temperature sterilization at 100 to 150°C. Retort sterilization, ultra-high temperature instant sterilization, etc. are used as sterilization methods. Retort sterilization involves filling and sealing a homogeneous liquid into packaging containers such as bottles, cans, and retort pouches, and heating and sterilizing them in an autoclave.
Sterilization is performed at 135° C. for 3 seconds to 30 minutes.

(Function) The concentrated liquid food thus obtained has a viscosity of 5 to 20 cp (
10°C), and can be easily and stably supplied to digestive organs such as the stomach and intestines by oral route or tube.

The concentrated liquid diet of the present invention administers the required nutritional amount of minerals and vitamins to patients with cerebrovascular disease and the elderly who have a low amount of energy to administer on a day or have a decreased ability to absorb minerals. and their deficiencies can be prevented.

(Effect of the invention) The present invention is a concentrated liquid food with high mineral content,
The following effects can be obtained by using a chelating agent.

(No separation, precipitation, or aggregation occurs even when stored at room temperature for 11 years.

(2) Even after sterilization, it maintains good emulsion stability, has excellent tube fluidity, and has no side effects such as diarrhea.

(3) Since it is a liquid product, it can be administered immediately orally or via tube, and is nutritionally superior.

(Examples) Next, the present invention will be explained in detail using Examples, Comparative Examples, and Test Examples. Hereinafter, percentages are based on weight.

Example 1 52.3 g of sodium hexametaphosphate (equivalent to 0.1%) was dissolved in 39.6 kg of water, and 2.
11 kg of sodium caseinate, 1.16 kg of whey protein, and 9.7 kg of dextrin were added and dissolved.

Meanwhile, 400 g of soybean oil, 50 g of safflower oil, and 42.5 g of lecithin were blended, and 30 g of decaglycerin monolaurate was added and dissolved. This blended lipid was mixed with the above aqueous solution, and further mixed with 8.2 g of vitamin mix at the blending ratio shown in Table 1.
The mixture was mixed with 3 g of mineral mix and pre-emulsified at 70° C. for 15 minutes using a propeller stirrer.

This preliminary emulsion was added to the first stage, 200 kg/cnl, 2
One homogenization process was performed by two-stage homogenization at 50 kg/cal to obtain an emulsion.

400 ml of this emulsion was filled into cans and sealed, and immediately retort sterilized in an autoclave at 115°C for 15 minutes to obtain canned concentrated liquid food.

The nutritional composition of this product is shown in Table 2.

The energy of this liquid is 1.0 Kcal/WIl. When this concentrated liquid food was left for one year, no syneresis or oil separation was observed, and the emulsion stability was good.

Example 2 Instead of sodium hexametaphosphate in Example 1, 78.3 g of sodium citrate and 711.5 g of a mineral mix having the mineral composition shown in Table 3 were mixed, and this emulsion was poured into a standing liquid. A concentrated liquid food was obtained in the same manner as in Example 1 except that it was filled into a pouch.

When this concentrated liquid food was left for one year, no syneresis or oil separation was observed, and the emulsion stability was good.

Table 4 shows the mineral content of this product.

Examples 3 to 5, Comparative Example 1.2 Example 2 using the potassium salt and chelating agent shown in Table 5
A concentrated liquid diet was obtained in the same manner.

Kaya table (per 100g of total composition) Vitamins - Vitamin A powder 1, 49mg Vitamin B1 Thiamine hydrochloride 0.06mg Vitamin B
Riboflavin diphosphate 0.06mg Vitamin B6 Pyridoxine hydrochloride 0.23mg Vitamin C2 85mg Vitamin D powder (200000111/g) 0.
03mg vitamin E powder (20χ) 8.
55mg Nicotinic acid amide 1.43
mg Calcium pantothenate 0.57 mg Folic acid 0.23 mg - Minerals - Sodium chloride 0.14 g Potassium chloride 0.32 g Potassium carbonate
0.04g calcium glycerophosphate 0.17g ferrous sulfate 1
．． 14-g magnesium chloride 0.10
1 g ball (per 100g of total composition) Protein 5.09g Lipid
0.92g carbohydrates
15.97g - Vitamins - Vitamin A 102.78 II
Vitamin B+ 0.06mg Vitamin B z 0.06mg Vitamin B 6 0.25mg Vitamin B l! 0.34mg Vitamin C2, 85mg Vitamin Vitamin 17.0910 Vitamin E 2.06mg Vitamin + 9.11gg Nicotinamide 1, 46mg Pantothenic Acid
0.64mg folic acid
24.38x-Minerals-Na 106.65m
gK 188.23m
gCa 39.1
9n+gFeO
,69+ag”g
13.44BP
3B, 29mgMn
0.01mg Cu
6.83 River Zn
O, 19mgCl
142.20g steel 1st dog (total composition 100g
per) Sodium chloride 0.12g Potassium chloride 0.49g Calcium glycerophosphate 0, 55g Ferrous sulfate
1.54mg magnesium chloride
0.10g soil surface (per 100g of total composition) Minerals - Na 92.59m
gK 259.26m
gCa 129.63
mgFeO,93
5g”8 1
3.98mgP
96.29mgM'
0.01mg Cu
6.83mgZn
0.19m
gCl 1
Performance tests were conducted on emulsion stability and average particle size using 85.29mg 5W Examples 1 to 5 and Comparative Example 1.2, and the results are shown in Table 5. From the results in Table 5, it is clear that the products of the present invention have extremely excellent emulsion stability immediately after manufacture and after storage for one year, and are administered orally and by tube. It could be used for nutritional supplementation.

The concentrated liquid food obtained in Examples 1 to 5 (1 kcal/ml)
An administration test was conducted on 5 hospitalized patients using this product, and comparison was made with commercially available product A (potassium content: 0.05% by weight, other mineral content: 10.36% by weight).

Table 6 shows the clinical course during administration for 14 to 57 days.

From the results in Table 6, commercial product A had a significant decrease in serum potassium level and exhibited potassium deficiency symptoms, but Example 1
In the products of the present invention No. 5 to 5, no decrease in serum potassium was observed, indicating good nutritional status. Furthermore, in patients treated with the present invention, no diarrhea or abdominal distention windows were observed, and good results were obtained in terms of clinical test items.

That is, it was confirmed that the product of the present invention has no side effects and can provide good nutritional support.

Claims (1)

[Claims] (1) In a concentrated liquid diet whose main components are protein or its decomposition products, carbohydrates, lipids, vitamins, and minerals, the potassium content in the minerals is 0.07 to 0 in the total composition.
．． 30% by weight, mineral content other than potassium is 0.25
-1.0% by weight, and further contains 0.02-0.15% by weight of a chelating agent.