JP7309161B1 - Adhesive - Google Patents

Abstract

[Problem] To provide a patch that is difficult to peel off even when it is attached to a portion of the skin where surface deformation is large. A patch (1A) comprising a base material layer (30) and an adhesive layer (40), in which four circular arc portions (11 to 14) and adjacent circular arc portions (11) are arranged symmetrically in four directions when viewed from above. , 12; 12, 13; 13, 14; ≧L2), the shortest distance between the four constricted parts facing each other is L3, and the longest distance between the arc parts 11, 13 (12, 14) on the diagonals of the imaginary rectangle 100 is L3. When the distance is L4, the following formula (1): 0.3≦(L1/L2)×(L3/L4)≦0.7 (1) is satisfied. [Selection drawing] Fig. 1

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an adhesive patch comprising a substrate layer and an adhesive layer to be attached to a wound.

This type of patch is widely used as a means of first aid for wounds in workplaces, homes, medical sites, and the like. As a patch for promoting wound healing, there is known one having a hydrocolloid layer that absorbs exuded bodily fluids (see, for example, Patent Document 1).

A general patch has a rectangular or square shape with rounded four corners (see Patent Document 2, for example). There is also a cross-shaped patch (see, for example, Patent Document 3).

JP 2012-100735 A JP-A-2002-639 Japanese Utility Model Laid-Open No. 52-155771

However, a patch having a rectangular shape such as a rectangle or a square as a basic shape can be applied to joints such as elbows and knees, between adjacent fingers, palms, Achilles tendons, and other areas where the skin is highly bent and stretched. When attached, the straight sides connecting adjacent corners may not be able to follow the surface deformation due to bending and stretching of the skin, and may be lifted and peeled off.

On the other hand, in the cross-shaped patch, the portions corresponding to the sides of the rectangular patch are notched at right angles. Since it is much smaller than when it is rectangular, it is easy to peel off.

SUMMARY OF THE INVENTION The present invention has been made in view of the above problems, and an object of the present invention is to provide an adhesive patch that is difficult to peel off even when it is attached to a portion of the skin where surface deformation is large.

The characteristic configuration of the patch according to the present invention for solving the above problems is
A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
Let L1 and L2 (L1≧L2) be the lengths of two sides of a virtual rectangle that inscribes the outline,
Let L3 be the shortest distance among the distances between the constricted portions facing each other in the four constricted portions,
When the longest distance among the distances between the circular arc portions at the diagonal corners of the virtual rectangle is L4,
Formula (1) below:
0.3≦(L1/L2)×(L3/L4)≦0.7 (1)
is configured to satisfy

According to the patch of this configuration, compared to the case where adjacent corners are connected at the shortest distance by straight sides like a conventional patch having a rectangular basic shape, the curved shape has a longer distance. Adjacent arcs are connected by the constricted part, so even if it is applied to areas with large bending and stretching of the skin, such as joints such as elbows and knees, between adjacent fingers, palms, Achilles tendons, etc. The constricted portion can absorb and follow the surface deformation caused by bending and stretching. In addition, in the patch of this configuration, (L1/L2)×(L3/L4) is set to 0.3 or more and 0.7 or less, so that two virtual rectangles that inscribe the outline in plan view The ratio of the lengths of the sides (L1/L2) to the depth (L3/L4) of the constricted portion in the direction toward the center of the rectangle is appropriate, and between the four circular arc portions symmetrically arranged in four directions It is possible to ensure a necessary and sufficient application area of the central portion that substantially covers the wound and is applied to the skin. In this way, it is possible to absorb and follow the surface deformation due to bending and stretching of the skin, and to secure a necessary and sufficient application area. Play.

The characteristic configuration of the patch according to the present invention for solving the above problems is
A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
Let L1 and L2 (L1=L2) be the lengths of two sides of a virtual rhombus that inscribes the outline,
Let L3 be the shortest distance among the distances between the constricted portions facing each other in the four constricted portions,
Let L41 be the longest distance (distance between tops) among the distances between the pair of arcs on the diagonal of the virtual rhombus, and the longest among the distances between the other pair of arcs on the diagonal of the virtual rhombus. Let the distance (distance between tops) be L42,
When the average of L41 and L42 is L4,
Equation (2) below:
0.4 ≤ (L1/L2) x (L3/L4) ≤ 0.6 (2)
is configured to satisfy

The patch of this configuration is configured to satisfy the above formula (2) when the contour in plan view is a virtual rhombus, the contour in plan view is a virtual rectangle, and the above formula ( It has basically the same effect as the adhesive patch configured to satisfy 1).

In the patch according to the present invention,
When the length of the chord of the arc portion is L5,
Equation (3) below:
1/7 ≤ L5/L2 ≤ 1/2 (3)
is preferably configured to satisfy

According to the patch of this configuration, since it is configured to satisfy the above formula (3), the length (L2) of one side of the two sides of the virtual rectangle or rhombus that inscribes the contour in plan view The length (L5) of the chord of the arc part is appropriate, the arc part does not have a sharp shape that is easily caught on clothes, etc., and it is set to an appropriate size that does not hinder the ability to follow the skin due to the constricted part. be done. As a result, even if an external force due to contact with clothes or the like acts, it is difficult for the adhesive to come off, and the central portion that substantially covers the wound can be reliably kept attached to the skin by the four arcuate portions.

The characteristic configuration of the patch according to the present invention for solving the above problems is
A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
The base layer has a 50% tensile load (A) of 2.3 N/10 mm or less measured according to JIS Z 0237,
The adhesive layer has an adhesive strength (B) to a PTFE (polytetrafluoroethylene) plate measured in accordance with JIS Z 0237 in the range of 1.5 to 7.0 N/10 mm.

According to the patch of this configuration, compared to the case where the adjacent corners of the conventional patch are connected at the shortest distance by the straight sides, Since the arcs are tied together, even if it is attached to areas where the skin is highly bent and stretched, such as joints such as elbows and knees, between adjacent fingers, palms, Achilles tendons, etc., the surface due to skin bending and stretching The constricted portion can absorb and follow the deformation. By the way, if the tensile load is too large, the patch will be difficult to stretch and will not easily follow the surface deformation of the skin. In addition, if the adhesive strength of the adhesive patch is too low, the patch cannot be stably attached to the skin. Therefore, in the patch of this configuration, the base layer has a 50% tensile load (A) measured in accordance with JIS Z 0237 set to 2.3 N / 10 mm or less, and the adhesive layer has a JIS Z 0237 Adhesive force (B) to the PTFE plate measured according to the standard is set in the range of 1.5 to 7.0 N/10 mm. As a result, it is possible to reliably ensure followability to the surface deformation of the skin, and it is possible to ensure the adhesion force to the skin, and it is possible to achieve the effect that it is difficult to peel off even if it is applied to a part of the skin where the surface deformation is large. Play.

In the patch according to the present invention,
It is preferable that the total thickness of the base material layer and the adhesive layer is 0.3 mm or less at the edges of the patch.

If the total thickness of the base layer and the adhesive layer at the edges of the patch is too large, the physical height of the edges relative to the skin increases, and the patch tends to be caught and rolled up when it rubs against clothes or the like. . Therefore, in the patch having this configuration, the total thickness of the base material layer and the adhesive layer is set to 0.3 mm or less at the edges of the patch. In this way, by setting the upper limit of the total thickness of the base layer and the adhesive layer at the edge of the patch to an appropriate value, the patch will not easily roll up even if it rubs against clothes, etc., and the wound will be stably protected. can do.

In the patch according to the present invention,
The base layer preferably has an elongation at break (C) of 200 to 800% as measured according to JIS Z 0237.

According to the patch of this configuration, the base layer has a breaking elongation (C) measured in accordance with JIS Z 0237 set to 200 to 800%, so that it is possible to ensure moderate elongation. can. As a result, when the patch is applied to the skin, it naturally follows the deformation of the surface of the skin. The operation of intentionally removing the patch from the skin can be easily performed.

In the patch according to the present invention,
The base material layer preferably has a surface dynamic friction coefficient of 1.0 or less.

According to the patch having this configuration, the base material layer has a surface dynamic friction coefficient set to 1.0 or less, so slipperiness can be ensured. As a result, the dynamic frictional force when rubbing with clothes or the like is reduced, and even if the cloth is rubbed with clothes or the like, it becomes difficult to roll up, and the wound can be stably protected.

In the patch according to the present invention,
The adhesion following coefficient (A/B) obtained from the ratio of the tensile load (A) and the adhesion force (B) is preferably 0.3 to 1.5.

In the patch, the tensile load (A) is mainly related to the ability to follow surface deformation of the skin, and the adhesive force (B) is mainly related to the peelability from the skin. Therefore, the tensile load (A) and the adhesive force are necessary in order to follow the deformation of the surface of the skin well in the state of sticking to the skin and to easily peel off without damaging the skin when intentionally removed from the skin. The balance with (B) is extremely important. Therefore, in the patch, in order to achieve both followability and peelability to the surface deformation of the skin and to facilitate handling, the patch of this configuration has a tensile load (A) and an adhesive force (B) of Adhesion follow-up coefficient (A/B) obtained from the ratio of is set to 0.3 to 1.5. Within such a range, when the adhesive is applied to the skin, it can follow the deformation of the surface of the skin, and the adhesive can be stably maintained. It can be reliably peeled off without slipping.

FIG. 1 is a diagram showing an adhesive material according to a first embodiment of the present invention. FIG. 2 is a diagram for explaining shape change when (L1/L2)×(L3/L4) is changed in the patch of the first embodiment. FIG. 3 is a diagram showing an adhesive material according to a second embodiment of the present invention. FIG. 4 is a diagram for explaining shape change when (L1/L2)×(L3/L4) is changed in the patch of the second embodiment. FIG. 5 is a diagram showing an adhesive material according to a third embodiment of the present invention. FIG. 6 is a diagram for explaining shape change when (L1/L2)×(L3/L4) is changed in the patch of the third embodiment. FIG. 7 is a diagram showing the shapes of samples of patch materials according to Examples 1-1 to 1-5 and Comparative Examples 1-1 and 1-2. FIG. 8 is a diagram showing the shapes of samples of patch materials according to Examples 2-1 to 2-8 and Comparative Examples 2-1 and 2-2. FIG. 9 is a diagram showing the shapes of samples of patch materials according to Examples 3-1 to 3-3 and Comparative Examples 3-1 and 3-2. FIG. 10 is a diagram showing the shapes of patch samples according to Examples 4-1 to 4-7 and Comparative Examples 4-1 and 4-2. FIG. 11 is a plan view of the patch showing the best mode in which L3/L4=0.50 and L5/L2=1/3.

The present invention will be described below with reference to the drawings. However, the present invention is not intended to be limited to the embodiments described below or the configurations described in the drawings. 1, 3, and 5 show that the patch of the present invention is composed of a plurality of layers, the thickness relationship of each layer is appropriately exaggerated or simplified for ease of explanation. , and does not strictly reflect the size relationship (scale) of the thickness of each layer in an actual patch. In this specification, the term "rectangle" means a rectangle or square, which is a quadrangle whose four interior angles are all equal in size. "Rhomboid" means a quadrilateral with four sides of equal length and opposite interior angles of equal size. Moreover, the symmetrical arrangement includes both point-symmetrical arrangement and line-symmetrical arrangement.

[First embodiment]
<Overall composition>
FIG. 1 is a diagram showing an adhesive material 1A according to the first embodiment of the present invention. FIG. 1(a) is a plan view of an adhesive patch 1A according to the first embodiment. As shown in FIG. 1(a), the patch 1A has four circular arc portions 11, 12, 13, 14 symmetrically arranged in four directions and adjacent circular arc portions 11, 12; 13; 13, 14; FIG. 1(b) is a cross-sectional view taken along the line AA in FIG. 1(a). As shown in FIG. 1(b), the adhesive patch 1A includes a base layer 30 and an adhesive layer 40 provided on the back side of the base layer 30 (the side that contacts the target (skin)). , the substrate layer 30 and the adhesive layer 40 are laminated in this order from the top to the bottom in the figure.

<Base material layer>
The base material layer 30 has a 50% tensile load (A) measured in accordance with JIS Z 0237 of 2.3 N/10 mm or less and a surface dynamic friction coefficient of 1.0 or less. For example, films, woven fabrics, non-woven fabrics, knitted fabrics, and foams made of polyurethane, polyester, polyamide, polyolefin, etc. can be used, although there is no particular limitation.

<Adhesive layer>
The adhesive layer 40 functions as a so-called hydrocolloid layer that absorbs exuded bodily fluids. The adhesive layer 40 has an adhesive strength (B) to a PTFE (polytetrafluoroethylene) plate measured in accordance with JIS Z 0237 in the range of 1.5 to 7.0 N/10 mm, and the patch 1A is applied to the skin. Although it is not particularly limited as long as it can be removably fixed to, it contains at least one kind of adhesive. The type of adhesive contained in the adhesive layer 40 is not particularly limited, but examples thereof include natural rubber adhesives, synthetic rubber adhesives, acrylic adhesives, urethane adhesives, and silicone adhesives.

<LB=(L1/L2)×(L3/L4)>
In the patch 1A shown in FIG. 1(a), the lengths of two sides of a virtual rectangle (rectangle in this example) 100 that inscribes the contour in plan view are L1 and L2 (L1>L2). L3 is the shortest distance between the constricted portions 21, 23; 22, 24 facing each other among the four constricted portions 21-24. Let L4 be the longest distance among the distances between the circular arc portions 11 and 13 (12 and 14) at the diagonal corners of the virtual rectangle 100 . When defined in this way, the patch 1A has the following formula (1):
0.3≦(L1/L2)×(L3/L4)≦0.7 (1)
is configured to satisfy

FIG. 2 is a diagram for explaining the shape change when changing (L1/L2)×(L3/L4), that is, LB, in the patch 1A of the first embodiment. In FIG. 2, L1 = 35 mm, L2 = 25 mm, and L4 = 40.4 mm, and the shape change of the patch 1 when the value of L3 is changed in multiple stages between 7.3 and 21.6 mm. In addition, it shows the shape change of the patch 1A when L1 = 50 mm, L2 = 25 mm, and L4 = 53.3 mm, and the value of L3 is changed in multiple stages between 6.7 and 20.0 mm. there is

As shown in FIG. 2, when LB becomes smaller than 0.3, the degree of depth of the constricted portions 22 and 24 in the direction toward the center of the imaginary rectangle 100 becomes too large, and the area of the portion covering the wound becomes becomes smaller. In addition, since the constricted portions 22 and 24 are not curved but bent at an obtuse angle, they cannot follow changes in the surface shape of the skin and are easily peeled off. On the other hand, if LB exceeds 0.7, the degree of depth of the constricted portions 22 and 24 in the direction toward the center of the imaginary rectangle 100 becomes too small, and the constricted portions 22 and 24 do not have a curved shape. Since it has a substantially straight shape, it cannot follow changes in the surface shape of the skin and is easily peeled off.

In the patch 1A, the value of LB is set in the range of 0.3 to 0.7 so as to satisfy the above formula (1). The degree of depth (L3/L4) of the constricted portions 21 to 24 in the direction toward the center of the virtual rectangle 100 with respect to the ratio (L1/L2) of the lengths of the two sides of the virtual rectangle 100 is appropriate, It is possible to ensure a necessary and sufficient application area of the central portion that substantially covers the wound and is applied to the skin between the four circular arc portions 11 to 14 that are symmetrically arranged in four directions. In this way, it is possible to absorb and follow the surface deformation due to bending and stretching of the skin, and to secure a necessary and sufficient application area. Play.

<Regulations on the arc part>
As shown in FIG. 1(a), when the chord length of the arc portions 11 to 14 is L5,
Equation (3) below:
1/7 ≤ L5/L2 ≤ 1/2 (3)
is preferably configured to satisfy

In the patch 1A, the length of one side (L2 ), the length (L5) of the arcs 11 to 14 becomes appropriate, the arcs 11 to 14 do not have a sharp shape that is likely to be caught on clothes, etc., and the constrictions 21 to 24 do not touch the skin. It is set to a moderate size that does not impede followability. As a result, even if an external force due to contact with clothes or the like is applied, it is difficult to peel off, and the four arc portions 11 to 14 can reliably maintain the sticking state to the skin of the central portion that substantially covers the wound.

<Tensile load (A)>
The base material layer 30 preferably has a 50% tensile load (A) of 2.3 N/10 mm or less measured according to JIS Z 0237. The elongation rate of the skin is about 50% at maximum, and it is necessary to consider the resistance value of the base material layer 30 when stretched by 50%. Since the resistance at 50% tension is sufficiently small, it can follow the bending and stretching of the skin. As shown in Table 1 below, the highest 50% tensile load was 3.65 N/20 mm among the measured values per 20 mm at 8 points on the patch 1A. Therefore, the upper limit of the 50% tensile load was set to 2.3 N/10 mm in consideration of the result of converting this measured value per 10 mm and the result of Example 5 described later. Thus, by setting the upper limit of the 50% tensile load (A) to an appropriate value, it is possible to reliably ensure followability to surface deformation of the skin.

<Adhesive strength (B)>
The adhesive layer 40 preferably has an adhesive strength (B) to a PTFE (polytetrafluoroethylene) plate measured according to JIS Z 0237 in the range of 1.5 to 7.0 N/10 mm. This range is based on the results of Example 6, which will be described later, in which adhesive force was measured using a PTFE plate as a test plate. Thus, by setting the value of the adhesive strength (B) to an appropriate range, it is possible to prevent the skin from being damaged and to prevent the adhesive from peeling off even when applied to a portion of the skin that undergoes large surface deformation.

<Total thickness of base layer and adhesive layer>
In the patch 1A, the total thickness of the base material layer 30 and the adhesive layer 40 is preferably 0.3 mm or less at the edges. If the total thickness of the base layer 30 and the adhesive layer 40 at the edges of the patch 1A is too large, the physical height of the edges relative to the skin increases, and when rubbed against clothing or the like, the adhesive may get caught. Easier to roll. Therefore, in the patch 1A, the total thickness of the base material layer 30 and the adhesive layer 40 is set to 0.3 mm or less at the edges of the patch 1A. Thus, by setting the upper limit of the total thickness of the base layer 30 and the adhesive layer 40 at the edge of the patch 1A to an appropriate value, it becomes difficult to roll up even if it rubs against clothes, etc., and the wound is stabilized. can be effectively protected.

In addition, in the patch 1A, it is preferable that the central portion has a relatively large thickness and the thickness decreases toward the edges. By adopting such a configuration, the thickness of the central portion that substantially covers the wound is relatively large, and the thickness decreases toward the edge, so that the edge tends to get caught when it rubs against clothes or the like. Since the thickness of the wound portion is relatively small, it is possible to reliably absorb external impacts and the like acting on the wound portion, and even if it rubs against clothing or the like, it will not easily roll up.

<Breaking elongation (C)>
In the patch 1A, the base layer 30 preferably has an elongation at break (C) of 200 to 800% as measured according to JIS Z 0237. As shown in Table 2 below, the maximum elongation measured at 8 points of the patch 1A is 211 to 234% at a breaking strength of 10 N/20 mm or more, which does not cause frequent tearing when peeled off.

Regarding the elongation at break, it is necessary to anticipate the elongation of the skin by about 50%. Taking into account the results of Example 5, 200% was set as the lower limit. In addition, in the patch 1A, if the surface of the base layer 30 is deeply embossed in order to improve the texture, the embossing will be the starting point for breakage in terms of mechanical strength. Since the elongation at break is close to 800% when the embossing is not performed, the upper limit of the elongation at break was set to 800%.

In the patch 1A, the base layer 30 has a breaking elongation (C) of 200 to 800%, which is measured according to JIS Z 0237, so that it is possible to ensure appropriate elongation. As a result, when the patch 1A is attached to the skin, it naturally follows the surface deformation of the skin, and if the patch 1A is pinched and pulled, it locally elongates and elongates, and the adhesive force decreases at an accelerated rate. , the operation of intentionally removing the patch 1A from the skin can be easily performed.

<Dynamic Friction Coefficient of Base Material Layer Surface>
In the patch 1A, the base layer 30 preferably has a surface dynamic friction coefficient of 1.0 or less. By setting the coefficient of dynamic friction of the surface of the base material layer 30 to 1.0 or less, slipperiness can be ensured. As a result, the dynamic frictional force when rubbing with clothes or the like is reduced, and even if the cloth is rubbed with clothes or the like, it becomes difficult to roll up, and the wound can be stably protected.

<Adhesive follow-up coefficient (A/B)>
In the patch 1A, it is preferable that the adhesion follow-up coefficient (A/B) obtained from the ratio of the tensile load (A) and the adhesion force (B) is 0.3 to 1.5. In the adhesive patch 1A, the tensile load (A) is mainly related to the followability to surface deformation of the skin, and the adhesive force (B) is mainly related to the releasability from the skin. Therefore, the tensile load (A) and the adhesive force are necessary in order to follow the deformation of the surface of the skin well in the state of sticking to the skin and to easily peel off without damaging the skin when intentionally removed from the skin. The balance with (B) is extremely important. Therefore, in the patch 1A, in order to achieve both the followability and peelability to the surface deformation of the skin and to facilitate handling, the patch 1A has a tensile load (A) and an adhesive force (B). The adhesion follow-up coefficient (A/B) obtained from the ratio of is set to 0.3 to 1.5. Within such a range, when the adhesive is applied to the skin, it can follow the deformation of the surface of the skin, and the adhesive can be stably maintained. It can be reliably peeled off without slipping.

[Second embodiment]
<Overall composition>
FIG. 3 is a diagram showing a patch 1B according to a second embodiment of the invention. FIG. 3(a) is a plan view of the patch 1B according to the second embodiment. FIG. 3(b) is a cross-sectional view taken along line BB of FIG. 3(a). In the first embodiment, the virtual rectangle that inscribes the contour in plan view is a rectangle, but in the second embodiment, the virtual rectangle that inscribes the contour in plan view is a square. is. Otherwise, it is basically the same as the first embodiment. Therefore, in the second embodiment, the same or similar parts as those in the first embodiment are denoted by the same reference numerals in the drawings, and detailed description thereof will be omitted. The explanation will focus on the part of

<LB=(L1/L2)×(L3/L4)>
In the patch 1B shown in FIG. 3(a), the lengths of two sides of a virtual rectangle (square in this example) 200 that inscribes the outline in plan view are L1 and L2 (L1=L2). L3 is the shortest distance between the constricted portions 21, 23; 22, 24 facing each other among the four constricted portions 21-24. Since the shortest distance between the constricted portions 21 and 23 and the shortest distance between the constricted portions 22 and 24 are both L3, the shortest distance between the constricted portions 22 and 24 is shown in FIG. Denote the distance as L3. Furthermore, let the longest distance among the distances between the circular arc portions 11 and 13 (12 and 14) at the diagonal corners of the virtual rectangle 200 be L4. When defined in this way, the patch 1B has the following formula (1):
0.3≦(L1/L2)×(L3/L4)≦0.7 (1)
is configured to satisfy

FIG. 4 shows (L1/L2)×(L3/L4) in the patch 1B of the second embodiment, that is, when LB is changed (L1=L2, so L3/L4 is substantially changed. It is a figure explaining the shape change of time). FIG. 4 shows the change in the shape of the patch 1B when L1=25 mm, L2=25 mm, and L4=32.8 mm, and the value of L3 is changed in multiple stages between 8.8 and 25 mm. there is

As shown in FIG. 4, when LB becomes smaller than 0.3, the degree of depth of the constricted portions 21 to 24 in the direction toward the center of the imaginary rectangle 200 becomes too large, and the area of the portion covering the wound becomes becomes smaller. In addition, since the constricted portions 21 to 24 are not curved but bent at a substantially right angle, they cannot follow changes in the surface shape of the skin and are easily peeled off. On the other hand, when LB exceeds 0.7, the degree of depth of the constricted portions 21 to 24 in the direction toward the center of the imaginary rectangle 200 becomes too small, and the constricted portions 21 to 24 do not have a curved shape. Since it has a substantially straight shape, it cannot follow changes in the surface shape of the skin and is easily peeled off.

In the patch 1B, the value of LB is set in the range of 0.3 to 0.7 so as to satisfy the above formula (1), so that the outline in plan view is inscribed as shown in FIG. The degree of depth (L3/L4) of the constricted portions 21 to 24 in the direction toward the center of the virtual rectangle 200 with respect to the ratio of the two sides of the virtual rectangle 200 (L1/L2=1) Thus, a necessary and sufficient application area can be ensured for the central portion that is applied to the skin while substantially covering the wound between the four circular arc portions 11 to 14 that are symmetrically arranged on the four sides. In this way, it is possible to absorb and follow the surface deformation due to bending and stretching of the skin, and to secure a necessary and sufficient application area. Play.

[Third embodiment]
<Overall composition>
FIG. 5 is a diagram showing an adhesive material 1C according to a third embodiment of the invention. FIG. 5(a) is a plan view of the patch 1C according to the third embodiment. FIG. 5(b) is a cross-sectional view taken along line CC of FIG. 5(a). In the third embodiment, a rhombus is a virtual figure that inscribes the contour in plan view. Otherwise, it is basically the same as the first embodiment. Therefore, in the third embodiment, the same or similar parts as those in the first embodiment are denoted by the same reference numerals in the drawings, and detailed description thereof will be omitted. The explanation will focus on the part of

<LB=(L1/L2)×(L3/L4)>
In the patch 1C shown in FIG. 5(a), the lengths of the two sides of the virtual rhombus 300 that inscribes the outline in plan view are L1 and L2 (L1=L2). L3 is the shortest distance between the constricted portions 21, 23; 22, 24 facing each other among the four constricted portions 21-24. Since the shortest distance between the constricted portions 21 and 23 and the shortest distance between the constricted portions 22 and 24 are both L3, the shortest distance between the constricted portions 22 and 24 is shown in FIG. Denote the distance as L3. Furthermore, let L41 be the longest distance (distance between the tops) of the distance between the pair of arc portions 11 and 13 that are diagonal to the virtual rhombus 300, and the other pair of arc portions 12 that are diagonal to the virtual rhombus 300. , 14, the longest distance (distance between tops) is L42, and the average of L41 and L42 is L4. When defined in this way, the patch 1C has the following formula (2):
0.4 ≤ (L1/L2) x (L3/L4) ≤ 0.6 (2)
is configured to satisfy

FIG. 6 is a diagram for explaining the shape change when (L1/L2)×(L3/L4), ie, LB, is changed in the patch 1C of the third embodiment. In FIG. 6, L1 = 25 mm, L2 = 25 mm, L4 = 32.2 mm (diagonal length ratio L42: L41 = 3: 4), and the value of L3 is set between 9.6 and 22.5 mm The shape change of the patch 1C when changed in multiple stages is shown, and fixed at L1 = 25 mm, L2 = 25 mm, and L4 = 30.6 mm (diagonal length ratio L42:L41 = 1:3 ^1/2 ). , L3 are changed in multiple stages between 9.2 and 21.4 mm.

As shown in FIG. 6, when LB becomes smaller than 0.4, the depth of the constricted parts 21 to 24 in the direction toward the center of the imaginary rhombus 300 becomes too large, and the area of the part covering the wound becomes becomes smaller. In addition, since the constricted portions 21 to 24 are not curved but bent at a substantially right angle, they cannot follow changes in the surface shape of the skin and are easily peeled off. On the other hand, when LB exceeds 0.6, the depth of the constricted portions 21 to 24 in the direction toward the center of the virtual rhombus 300 becomes too small, and the constricted portions 21 to 24 do not have a curved shape. Since it has a substantially straight shape, it cannot follow changes in the surface shape of the skin and is easily peeled off.

In the patch 1C, the value of LB is set in the range of 0.4 to 0.6 so as to satisfy the above formula (2), so that the outline in plan view is inscribed as shown in FIG. The degree of depth (L3/L4) of the constricted portions 21 to 24 in the direction toward the center of the virtual rhombus 300 with respect to the ratio of the two sides of the virtual rhombus 300 (L1/L2=1) Thus, a necessary and sufficient application area can be ensured for the central portion that is applied to the skin while substantially covering the wound between the four circular arc portions 11 to 14 that are symmetrically arranged on the four sides. In this way, it is possible to absorb and follow the surface deformation due to bending and stretching of the skin, and to secure a necessary and sufficient application area. Play.

As described above, the patch of the present invention has been described based on a plurality of embodiments, but the present invention is not limited to the configurations described in the above embodiments, and the configuration can be changed as appropriate without departing from the scope of the invention. It is something that can be done.

Examples of the patch of the present invention are described below. However, the present invention is not limited to these examples.

[Embodiment of a patch having a contour shape inscribed in a virtual rectangle]
(Examples 1-1 to 1-5, Comparative Examples 1-1 and 1-2)
FIG. 7 is a diagram showing the shapes of samples of patch materials according to Examples 1-1 to 1-5 and Comparative Examples 1-1 and 1-2. Using the scratch quick fit original fabric manufactured by Toyo Kagaku Co., Ltd., L1 is 50 mm, L2 is 25 mm, L5 is 6.25 mm, and LB = (L1 / L2) × (L3 / L4) is 0.30 to 0. Five patch samples were prepared in the range of 0.70, and designated as Examples 1-1 to 1-5. A patch sample having an LB of 0.25 which is less than 0.30 was designated Comparative Example 1-1, and a patch sample having an LB of 0.75 exceeding 0.70 was designated Comparative Example 1-2.

The samples according to Examples 1-1 to 1-5 and the samples according to Comparative Examples 1-1 and 1-2 were applied to 6 subjects on fists, palms, knees, heels, toes, and toes. A 24-hour application test was performed on the crotch. With 24 hours as the upper limit, the time until peeling started and the time until all peeled off (falling off) were evaluated. If it was possible to continue the application even after the adhesive began to peel off, the application was continued until the adhesive tape fell off. A sample that did not peel off for 8 hours or longer after application was evaluated as ◯, and a sample that did not peel for 12 hours or longer was evaluated as ⊚. Samples that did not come off for 12 hours or longer after application were evaluated as ◯, and samples that did not come off for 16 hours or longer were evaluated as ⊚. Samples other than the above were marked with x. Results are shown in Tables 3 and 4.

As shown in Tables 3 and 4, the samples of Examples 1-1 to 1-5 with LB values in the range of 0.30 to 0.70 did not come off for 8 hours or more after application. Moreover, it did not come off for 12 hours or more after application. On the other hand, in Comparative Examples 1-1 and 1-2 in which the value of LB is out of the range of 0.30 to 0.70, the time to start peeling is shorter than 8 hours and 12 hours. There were parts that fell off too quickly.

[Embodiment of a patch having a contour shape inscribed in a virtual square]
(Examples 2-1 to 2-8, Comparative Examples 2-1 and 2-2)
FIG. 8 is a diagram showing the shapes of samples of patch materials according to Examples 2-1 to 2-8 and Comparative Examples 2-1 and 2-2. Using a scratch quick fit raw material manufactured by Toyo Kagaku Co., Ltd., L1 and L2 are each 25 mm, L5 is 6.25 mm, and LB = (L1 / L2) × (L3 / L4) is 0.30 to 0.30. Eight adhesive patch samples were prepared in the range of 70, and designated as Examples 2-1 to 2-8. A patch sample having an LB of 0.28, which is less than 0.30, was designated Comparative Example 2-1, and a patch sample having an LB of 0.76, which exceeded 0.70, was designated Comparative Example 2-2.

The samples according to Examples 2-1 to 2-8 and the samples according to Comparative Examples 2-1 and 2-2 were applied to 6 subjects on fists, palms, knees, heels, toes, and toes. A 24-hour application test was performed on the crotch. With 24 hours as the upper limit, the time until peeling started and the time until all peeled off (falling off) were evaluated. If it was possible to continue the application even after the adhesive began to peel off, the application was continued until the adhesive tape fell off. A sample that did not peel off for 8 hours or longer after application was evaluated as ◯, and a sample that did not peel for 12 hours or longer was evaluated as ⊚. Samples that did not come off for 12 hours or longer after application were evaluated as ◯, and samples that did not come off for 16 hours or longer were evaluated as ⊚. Samples other than the above were marked with x. Results are shown in Tables 5 and 6.

As shown in Tables 5 and 6, Examples 2-1 and 2 in which the value of LB (substantially the value of L3/L4 since L1 = L2 = 25 mm) is in the range of 0.30 to 0.70 All of the -8 samples were not peeled off for 8 hours or more after application. Moreover, it did not come off for 12 hours or more after application. On the other hand, in Comparative Examples 2-1 and 2-2, in which the LB value is outside the range of 0.30 to 0.70, the time until peeling started was shorter than 8 hours in some parts. No site fell off earlier than 12 hours.

[Embodiment of a contour-shaped patch inscribed in a virtual rhombus]
(Examples 3-1 to 3-3, Comparative Examples 3-1 and 3-2)
FIG. 9 is a diagram showing the shapes of samples of patch materials according to Examples 3-1 to 3-3 and Comparative Examples 3-1 and 3-2. Using a scratch quick fit raw material manufactured by Toyo Kagaku Co., Ltd., L1 and L2 are each 25 mm, L5 is 6.25 mm, and LB = (L1 / L2) × (L3 / L4) is 0.40 to 0.40. Three adhesive patch samples were prepared in the range of 60, and designated as Examples 3-1 to 3-3. A patch sample having an LB of 0.30, which is less than 0.40, was designated Comparative Example 3-1, and a patch sample having an LB of 0.70, which exceeded 0.60, was designated Comparative Example 3-2.

The samples according to Examples 3-1 to 3-3 and the samples according to Comparative Examples 3-1 and 3-2 were applied to 6 subjects on fists, palms, knees, heels, toes, and toes. A 24-hour application test was performed on the crotch. With 24 hours as the upper limit, the time until peeling started and the time until all peeled off (falling off) were evaluated. If it was possible to continue the application even after the adhesive began to peel off, the application was continued until the adhesive tape fell off. A sample that did not peel off for 8 hours or longer after application was evaluated as ◯, and a sample that did not peel for 12 hours or longer was evaluated as ⊚. Samples that did not come off for 12 hours or longer after application were evaluated as ◯, and samples that did not come off for 16 hours or longer were evaluated as ⊚. Samples other than the above were marked with x. Results are shown in Tables 7 and 8.

As shown in Tables 7 and 8, Examples 3-1 to 3 in which the value of LB (substantially the value of L3/L4 since L1 = L2 = 25 mm) is in the range of 0.40 to 0.60 All the samples of -3 did not come off for 8 hours or more after application. Moreover, it did not come off for 12 hours or more after application. On the other hand, in Comparative Examples 3-1 and 3-2, in which the LB value is out of the range of 0.40 to 0.60, there were portions where the time until peeling started was shorter than 8 hours. No site fell off earlier than 12 hours.

[Example showing the relationship between the size of the arc portion and the start of peeling and falling off]
(Examples 4-1 to 4-7, Comparative Examples 4-1 and 4-2)
FIG. 10 is a diagram showing the shapes of patch samples according to Examples 4-1 to 4-7 and Comparative Examples 4-1 and 4-2. Using the scratch quick fit original fabric manufactured by Toyo Kagaku Co., Ltd., L1 and L2 are each 25 mm, the value of LB (because L1 = L2 = 25 mm, the value of L3 / L4) is 0.5, L5 Seven patch samples were prepared so that /L2 was in the range of 1/7 to 1/2, and designated as Examples 4-1 to 4-7. Comparative example 4-1 for a patch sample in which L5/L2 is 1/7.8 which is less than 1/7, and a patch sample in which L5/L2 is 1/1.5 exceeding 1/2 for comparative example 4-2.

The samples according to Examples 4-1 to 4-7 and the samples according to Comparative Examples 4-1 and 4-2 were applied to 6 subjects on fists, palms, knees, heels, toes, and toes. A 24-hour application test was performed on the crotch. With 24 hours as the upper limit, the time until peeling started and the time until all peeled off (falling off) were evaluated. If it was possible to continue the application even after the adhesive began to peel off, the application was continued until the adhesive tape fell off. A sample that did not peel off for 8 hours or longer after application was evaluated as ◯, and a sample that did not peel for 12 hours or longer was evaluated as ⊚. Samples that did not come off for 12 hours or longer after application were evaluated as ◯, and samples that did not come off for 16 hours or longer were evaluated as ⊚. Samples other than the above were marked with x. Results are shown in Tables 9 and 10.

As shown in Tables 9 and 10, the samples of Examples 4-1 to 4-7 with L5/L2 in the range of 1/7 to 1/2 did not come off for 8 hours or more after application. Moreover, it did not come off for 12 hours or more after application. On the other hand, in Comparative Examples 4-1 and 4-2, in which the value of L5/L2 is outside the range of 1/7 to 1/2, the time to start peeling is shorter than 8 hours, and 12 hours. There was a part that fell off earlier than time.

As a result of comprehensive examination, a planar adhesive material 1B as shown in FIG. ', the balance between the size of the central portion and the size of the circular arc portions 11 to 14 is optimal, and it has been found to be the best mode.

[Example regarding 50% tensile load (A) and breaking elongation (C)]
(Example 5)
A 150 μm-thick scratch-quick adhesive manufactured by Toyo Kagaku Co., Ltd. was applied to 9 types of membranous materials (films, non-woven fabrics, and composites thereof) having different properties and materials to obtain patches. A tensile test was carried out on this patch in the winding direction (MD direction) and the width direction (CD direction) to measure the 50% tensile load and breaking strength. In addition, the patch was cut into a size of 20 × 50 mm, and the patch was pasted along the direction of the arm so that the center of the patch was positioned at the tip of the elbow of the six subjects when the elbow was bent. , one time of bending and stretching was performed in 2 seconds, and the sticking feeling was evaluated after 10 times of bending and stretching. The results are shown in Table 11.

According to Takashi Harada et al.'s literature (skin stretch and clothing stretch, textile engineering VOL.36, NO.6), the stretch of the rear elbow (elbow) is in the range of 30 to 62%, so when stretched at a certain rate The elongation rate of each patch was set to 50%, and the resistance value of each patch was evaluated as a 50% tensile load. All of the polyurethane films (films A to D) used in this example had a 50% tensile load of 2.3 N/10 mm or less. All the films had a good sticking feeling. The polyurethane nonwoven fabric (Nonwoven fabric E) also had a good sticking feeling. On the other hand, one person answered that nonwoven fabric + film F, in which a polyurethane film was attached to a polyurethane nonwoven fabric, was not good. In addition, as seen in polyester nonwoven fabric I, even if the resistance in one direction (CD direction) is 2.3 N/10 mm or less, when the resistance in the other direction (MD direction) is extremely large, a good sticking feeling is obtained. I also found out that it will be gone.

From the results in Table 11, a highly flexible material such as polyurethane is suitable as the adhesive material, and such a material has the property of being stretched well and broken. It can be set to 800%.

[Example regarding adhesive strength (B)]
(Example 6)
For various adhesives with different basic formulations and compounding ratios of Kizu Quick adhesive manufactured by Toyo Kagaku Co., Ltd., the adhesive strength to PTFE plate was measured in accordance with JIS Z 0237, and at the same time, L1 = L2 = 25 mm in Fig. 11 The peeled sample was applied to the healthy skin on the inner side of the forearm of 6 test subjects for 8 hours, and then the state of peeling and the pain when peeled off were examined. The results are shown in Table 12.

In Formulation 1, there was no pain at all when peeled off, but peeling was observed in 4 out of 6 test subjects 8 hours after application, and it could not be said that the adhesive strength to the skin was practical. In Formulation 2, peeling was observed in one subject, but the adhesion to the skin was greatly improved, and it was judged that it reached a practical level. was the lower limit of the adhesive strength. On the other hand, in formulation 5, half of the 6 subjects complained of pain during peeling, so it was judged that the adhesive strength was too strong. If the adhesive strength is too strong, there is a concern that the surface of the skin that is in the process of healing may be peeled off when the adhesive is reapplied, which is not appropriate for the function of the product. In formulation 4, one subject complained of pain during peeling, but the pain during peeling was significantly improved compared to formulation 5, and it was determined that it had reached a practical level, so 7.0 N /10 mm was taken as the upper limit of adhesive strength of this patch.

[Example of Total Thickness of Base Layer and Adhesive Layer]
(Example 7)
A Taber abrasion test was carried out in accordance with JIS K 7204 to determine the resistance to peeling when applied. Using the scratch quick fit raw material manufactured by Toyo Kagaku Co., Ltd., the total thickness (base material thickness + adhesive thickness) is 0.20, 0.25, 0.30, 0.35, 0.40, 0.50 mm , and four arcs for each of the shape according to Example 2-4 in FIG. 8, the shape according to Example 4-6 in FIG. 10, and the shape shown in FIG. Installed so that two central parts of the part pass through, a friction force test was performed under the conditions of a load of 250 g, a wear wheel CS-5, and the number of frictions of 100 times. examined the number of samples. The results are shown in Table 13.

The Taber abrasion test is an index of peeling due to contact with clothing when attached. If the total thickness (base layer + adhesive layer) is 0.30 mm or less, peeling will not occur even when rubbing against clothing. thought to be difficult. Since only the edges of the product come into contact with clothes, if the thickness of the edges is 0.30 mm or less, even if the central part of the product is thicker than that, it can be considered that peeling due to friction will not be affected. can.

[Example regarding dynamic friction coefficient]
(Example 8)
The slipperiness and resistance to peeling of the patch were measured by partially modifying the method specified in JIS K 8147. The maximum load on the load cell of the constant speed extension tensile tester was 10 N, and the flattest possible place on the forearm was used instead of the horizontal plate. A 20 mm square brass cube was used as the weight. A method of attaching the adhesive material of the present invention to one surface of the weight so as not to cause scratches or wrinkles, placing the attached surface on the forearm, and pulling a hook attached to the weight via a thin metal wire. bottom. A pulley was fixed to the hanging part of the load cell, and by positioning the pulley just above the wrist, the weight could be moved horizontally. The moving speed of the weight was 100 mm per minute, the moving distance of the weight was 50 mm, and the frictional force was recorded. The dynamic friction coefficient was obtained by dividing the obtained average dynamic friction force by the vertical load of the weight.

The raw material of Kizuquik Fit manufactured by Toyo Kagaku Co., Ltd. varies in slipperiness depending on the degree of embossing on the surface, and the slipperiness is determined by the embossed shape transferred from the process paper during film production of the raw material. Using three types of process paper with different embossed shapes, samples with a total thickness of 0.2 mm and shapes as shown in FIG. The number of arc portions peeled off after being applied to the side of the thumb of the index finger of the dominant hand for 4 hours was confirmed. The results are shown in Table 14.

When the coefficient of dynamic friction is 1.00 or less, the texture is good and moderate slipperiness can be obtained. From the results in Table 14 above, it was found that when the coefficient of dynamic friction was 1.00 or less, a patch having a slippery surface that was difficult to peel off was obtained.

INDUSTRIAL APPLICABILITY The patch of the present invention can be used for application to a wound site as a means of emergency treatment for wounds in workplaces, homes, medical sites, and the like.

1A to 1C adhesive material 11 to 14 arc portion 21 to 24 constricted portion 30 base layer 40 adhesive layer 100 imaginary rectangle (rectangle)
200 virtual rectangle (square)
300 virtual rhombus

Claims (6)

A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
Let L1 and L2 (L1≧L2) be the lengths of two sides of a virtual rectangle that inscribes the outline,
Let L3 be the shortest distance among the distances between the constricted portions facing each other in the four constricted portions,
When the longest distance among the distances between the circular arc portions at the diagonal corners of the virtual rectangle is L4,
Formula (1) below:
0.3≦(L1/L2)×(L3/L4)≦0.7 (1)
configured to satisfy
When the length of the chord of the arc portion is L5,
Equation (3) below:
1/5 ≤ L5/L2 ≤ 1/3 (3)
An adhesive configured to meet A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
Let L1 and L2 (L1=L2) be the lengths of two sides of a virtual rhombus that inscribes the outline,
Let L3 be the shortest distance among the distances between the constricted portions facing each other in the four constricted portions,
Let L41 be the longest distance (distance between tops) among the distances between the pair of arcs on the diagonal of the virtual rhombus, and the longest among the distances between the other pair of arcs on the diagonal of the virtual rhombus. Let the distance (distance between tops) be L42,
When the average of L41 and L42 is L4,
Equation (2) below:
0.4 ≤ (L1/L2) x (L3/L4) ≤ 0.6 (2)
configured to satisfy
When the length of the chord of the arc portion is L5,
Equation (3) below:
1/5 ≤ L5/L2 ≤ 1/3 (3)
An adhesive configured to meet A patch comprising a substrate layer and an adhesive layer,
The contour in a plan view is composed of four circular arc portions symmetrically arranged in four directions and four constricted portions connecting adjacent circular arc portions,
The base layer has a 50% tensile load (A) of 2.3 N/10 mm or less measured according to JIS Z 0237,
The adhesive layer has an adhesive strength (B) to a PTFE (polytetrafluoroethylene) plate measured in accordance with JIS Z 0237 in the range of 1.5 to 7.0 N / 10 mm ,
An adhesive patch having an adhesive follow-up coefficient (A/B) determined from the ratio of the tensile load (A) and the adhesive strength (B) of 0.3 to 1.5. The patch according to any one of claims 1 to 3, wherein the total thickness of the base material layer and the adhesive layer is 0.3 mm or less at the edges of the patch. The patch according to any one of claims 1 to 3 , wherein the base layer has an elongation at break (C) of 200 to 800% as measured according to JIS Z 0237. The patch according to any one of claims 1 to 3, wherein the base material layer has a surface dynamic friction coefficient of 1.0 or less.

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