JP6433792B2 - Particle beam therapy apparatus and imaging method using the same - Google Patents

Description

Embodiments of the present invention, heavy ion beams or proton beams, etc. of the particle beam such as carbon (hereinafter, simply referred to as beams.) Was irradiated with, for example, in the affected area, a cancer treatment line cormorants particle slave beam therapy system and The present invention relates to an imaging method using the same.

  Currently, for example, a particle beam irradiation method is used for cancer treatment. As this particle beam irradiation method, there is a method called an expanded beam method. In this expanded beam method, the beam diameter is expanded beyond the size of the affected area by a method called the wobbler method or the double scatterer method. In the expanded beam method, irradiation is performed in accordance with the shape of the affected area by limiting the irradiation area with a collimator. However, the expanded beam method cannot strictly match the shape of the affected area three-dimensionally, and there is a limit to reducing the influence on normal cells around the affected area.

  Therefore, a three-dimensional scanning irradiation method was developed. In this three-dimensional scanning irradiation method, a fluoroscopic image obtained by X-ray photography is compared with a reference image prepared in advance by a computed tomography (hereinafter abbreviated as CT) image, and a positional deviation amount is compared. Seeking. Then, the shift amount of this position is set in the treatment bed so that the fluoroscopic image and the reference image are matched. Since this image alignment is a comparison between two-dimensional images, it is called 2D (dimensions) -2D positioning.

  However, as a method for performing positioning with higher accuracy, there is a method in which a CT apparatus is installed in a treatment room, CT imaging is performed in a state where a patient is mounted on a treatment bed, and a CT image for treatment planning is compared. This method is called 3D (dimensions) -3D positioning because it is a comparison between three-dimensional images.

JP 2010-94221 A

JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, Vol.13, Num. 6,2012, Patient handling system for carbon ion beam scanning therapy, S. Mori, et.al.

  However, in the conventional three-dimensional scanning irradiation method, when CT imaging is performed with a patient placed near the isocenter, if the CT device is installed near the isocenter, the CT device and the irradiation port interfere with each other. To do. Therefore, CT imaging could not be performed with the patient positioned near the isocenter.

An object of the present embodiment is to provide is to provide an imaging method using particle slave beam therapy system and this can be avoid interference between CT apparatus and the particle beam irradiation apparatus.

In order to solve the above problems, a particle beam treatment apparatus according to the present embodiment includes a particle beam irradiation apparatus that irradiates an affected area of a patient with a particle beam, and a CT apparatus that acquires a three-dimensional image of the patient in the body. a particle beam therapy system that includes irradiation, the particle beam irradiation apparatus includes a beam scanning magnet to scan the particle beam 2 dimensional, two-dimensional scanned particle beam by the beam scanning magnets to the affected area of the patient It has a radiation port for the said irradiation port, the irradiated port fixation section having a position monitor for detecting the position of the particle beam, a movable irradiation port movable portion with respect to the irradiation port fixation section have a, the irradiation port, the a vicinity of the CT apparatus, the CT is installed in a moving range at the time of image acquisition devices, and the CT apparatus the irradiation port said during image acquisition C of Characterized in that the irradiation port movable portion such that the outside the movement range of the device is movable.

Furthermore, an imaging method using the particle beam therapy system of this embodiment is an imaging method for imaging the internal three-dimensional image by the particle beam therapy system, the moving range of the previous SL irradiation port movable portion and the CT device After the irradiation port movable part moving step for moving outside, the CT port moving step for moving the CT device to the image acquisition position after the irradiation port movable portion moving step, and the CT device moving step, the CT device is moved. And an image acquisition step of acquiring a three-dimensional image of the patient in the body.

According to this embodiment, it is possible to avoid interference between the CT apparatus and the particle beam irradiation apparatus .

It is an elevation lineblock diagram showing the particle beam therapy system of one embodiment. It is a schematic block diagram which shows the positional relationship of CT apparatus of FIG. 1, and an irradiation port. It is a flowchart which shows an example of the treatment order using the particle beam therapy apparatus of one Embodiment. It is a flowchart which shows an example of the irradiation procedure using the scanning irradiation apparatus of one Embodiment.

  Hereinafter, a particle beam irradiation apparatus, a particle beam therapy apparatus, and an imaging method using the same according to the present embodiment will be described with reference to the drawings.

(One embodiment)
FIG. 1 is an elevational view showing a particle beam therapy system according to an embodiment. FIG. 2 is a schematic configuration diagram showing a positional relationship between the CT apparatus of FIG. 1 and an irradiation port.

  As shown in FIG. 1, the particle beam therapy system according to the present embodiment includes a scanning irradiation apparatus 1 as a particle beam irradiation apparatus, a CT apparatus 2 that is another apparatus for the scanning irradiation apparatus 1, and an X-ray imaging apparatus. 3 and a treatment bed 4. The irradiation port 10, the CT apparatus 2, the X-ray imaging apparatus 3, and the treatment bed 4 of the scanning irradiation apparatus 1 are installed in the treatment room 14. The irradiation port 10 of the scanning irradiation apparatus 1 is disposed in the vicinity of the CT apparatus 2 and within a moving range when the CT apparatus 2 acquires an image (during imaging).

  The X-ray imaging apparatus 3 includes two sets, X-ray tubes 5a and 5b are installed under the floor 19, and a flat panel detector (hereinafter abbreviated as FPD) is attached to the ceiling 9. FPDs 6a and 6b are installed at the distal ends of the mechanisms 7a and 7b, and are configured to acquire in-vivo fluoroscopic images from two directions.

  The FPDs 6a and 6b can be moved up and down by driving the FPD driving mechanisms 7a and 7b, respectively. The FPDs 6a and 6b are in a lowered position when acquiring a fluoroscopic image. Further, when the CT apparatus 2 moves to the position of the treatment bed 4 at the CT imaging position, the FPDs 6a and 6b are raised to a position where they do not interfere with the CT apparatus 2.

  An irradiation port 10 for irradiating a patient mounted on the treatment bed 4 with a beam is installed at the distal end of the scanning irradiation apparatus 1. The irradiation port 10 is configured separately from the irradiation port movable unit 20 and the irradiation port fixing unit 30. The irradiation port movable unit 20 can move horizontally with respect to the irradiation port fixing unit 30 and is located within the movement range of the CT apparatus 2. When the CT apparatus 2 moves to the position of the treatment bed 4, the irradiation port movable unit 20 moves horizontally to a position that does not interfere with the CT apparatus 2.

  The scanning irradiation apparatus 1 includes an irradiation port 10 disposed in the treatment room 14, a scanning electromagnet 11 as a beam scanning electromagnet installed outside the treatment room 14, and a vacuum duct 12. One end of the vacuum duct 12 is fixed to the upstream side of the irradiation port 10, and the other end extends through the scanning electromagnet 11 to an accelerator take-out device 18 described later.

  The irradiation port movable unit 20 is disposed on the beam downstream side with respect to the decorative wall 13 standing in the treatment room 14. A range shifter 21 and a ridge filter 22 as a range adjuster are installed in the irradiation port movable unit 20.

  The irradiation port fixing part 30 is arranged on the beam upstream side with respect to the decorative wall 13. In the irradiation port fixing part 30, a part of the vacuum duct 12, a position monitor 31, and a dose monitor 32 are installed.

  The CT apparatus 2 is self-propelled and is configured to be movable to the treatment bed 4 along two rails 33 laid on the floor surface in the treatment room 14. Specifically, the CT apparatus 2 includes a plurality of traveling wheels 34 that travel on two rails 33, and any of these traveling wheels 34 is connected to the output shaft of the drive motor 35 shown in FIG. Has been. Therefore, when the drive motor 35 is driven, the traveling wheel 34 travels along the two rails 33, so that the CT apparatus 2 can move to the treatment bed 4.

  At the time of CT imaging by the CT apparatus 2, the irradiation port movable unit 20 is in a position where it interferes. In this case, the irradiation port movable unit 20 is moved horizontally to prevent interference with the CT apparatus 2.

  The treatment bed 4 is configured to be movable up and down and left and right by a drive unit (not shown) in order to finely adjust the position of the affected part of the patient on which it is mounted.

  As shown in FIG. 2, the irradiation port movable unit 20 is fixed to a substantially square reinforcing frame 23 that penetrates the decorative wall 13, a decorative cover 26 that covers the reinforcing frame 23, and the upper and lower inner surfaces of the decorative cover 26. Rails 24 movable along the reinforcing frame 23, a plurality of rollers 25 for horizontally moving the rails 24, and a drive motor (not shown) having an output shaft coupled to the rollers 25. This drive motor is arranged on the beam upstream side with respect to the decorative wall 13.

  Therefore, when the drive motor is driven, the roller 25 to which the output shaft is connected rotates and the rail 24 moves horizontally, so that the irradiation port movable unit 20 does not interfere with the CT apparatus 2 so that the treatment bed 4 does not interfere. To the retreat position (the position indicated by the two-dot chain line).

  The reinforcing frame 23 of the irradiation port movable part 20 is covered with a decorative cover 26 so that it cannot be seen as much as possible from the treatment room 14 side so as not to impair the appearance design of the treatment room 14. Further, a beam extraction window 20a is provided in the beam extraction unit so that the components of the irradiation port fixing unit 30 cannot be seen from the beam extraction unit.

  Next, the function of each device of the scanning irradiation apparatus 1 shown in FIG. 1 will be described.

  The ion source 15, the linear accelerator 16, and the synchrotron 17 constitute a beam generation unit of the present embodiment. Specifically, the beam generating unit generates ions by accelerating ions generated by the ion source 15 to energy that can reach deep into the affected area by the linear accelerator 16 and the synchrotron 17.

  That is, the linear accelerator 16 accelerates ions generated by the ion source 15. A beam accelerated by the linear accelerator 16 is transported to the synchrotron 17, and this beam is circulated to further accelerate to a predetermined energy. After the acceleration of the beam, the beam is taken out by the take-out device 18 and transported to the vacuum duct 12 penetrating the scanning electromagnet 11.

  The scanning electromagnet 11 scans the particle beam 8 incident on the scanning electromagnet 11 at a point (X, Y) on a plane (slice plane) perpendicular to the beam axis in the affected area in the body. This beam scanning is performed by controlling the output current of a scanning electromagnet power source (not shown).

  The range shifter 21 controls the position (Z) in the beam axis direction within the affected area in the body. The range shifter 21 is composed of an acrylic plate having a plurality of thicknesses, and by combining these acrylic plates, the beam energy passing through the range shifter 21, that is, the range within the body, is adjusted step by step according to the slice surface of the affected area. Can be changed. In-vivo range control in the range shifter 21 is generally switched at regular intervals. In addition to the method of inserting an object into the beam line such as the range shifter 21, there is a method of changing the beam energy itself by electrically controlling a device installed on the upstream side of the beam for switching the range. .

  The ridge filter 22 is used to expand a very sharp peak dose in the body depth direction (referred to as a Bragg peak) of the monoenergetic particle beam so as to correspond to the interval of the body range switched by the range shifter 21. It is.

  The scanning ridge filter 22 is configured by arranging a plurality of aluminum rod pieces. These bar pieces are formed in an approximately isosceles triangle shape, and the beam energy changes depending on the difference in the beam path length.

  The position monitor 31 is for identifying whether or not the beam position scanned by the scanning electromagnet 11 is at the correct position. The position monitor 31 has the same configuration as that of the dose monitor 32, and is divided into strips (strip type), or uses a collection electrode composed of a plurality of wires in a container (multi-wire type). used.

  The dose monitor 32 is for measuring the irradiation dose, and an ionization chamber or the like that collects charges generated by the ionizing action of the particle beam in the container with parallel electrodes is used.

  Next, a treatment procedure using the scanning irradiation apparatus 1 configured as described above will be described. FIG. 3 is a flowchart showing an example of a treatment sequence using the particle beam therapy system according to the embodiment.

  As shown in FIG. 3, first, CT imaging is performed in the treatment room 14 in which the CT apparatus 2 is installed in advance (step S1). At this time, the position estimated as the center of the affected part is marked on the surface of the fixture for fixing the patient to the treatment bed 4.

  In step S <b> 2, a treatment plan is made using the CT image acquired in the treatment room 14. In this treatment plan, irradiation data describing the setting of the irradiation region and how to perform irradiation for this irradiation region and the position setting data of the treatment bed 4 are created. Further, a two-dimensional image (DRR: Digitally reconstructed radiograph digital reconstruction simulation image) obtained by making the CT image two-dimensional is created.

  Next, the flow on the day of treatment will be described.

  A patient is mounted on the treatment bed 4 and the patient is fixed with a fixture. The treatment bed 4 is moved so that the mark marked in the treatment room 14 matches the isocenter (step S3).

  Next, it is determined whether CT imaging is performed in step S4, and it is determined whether X-ray imaging is performed in step S5.

  When performing CT imaging in step S4, the irradiation port movable unit 20 is moved horizontally. That is, a driving motor (not shown) is driven, the roller 25 to which the output shaft is connected is rotated, and the rail 24 is moved horizontally so that the irradiation port movable unit 20 does not interfere with the CT apparatus 2 from the treatment bed 4. Move horizontally to the retreat position. Then, the CT motor 2 is moved to the treatment bed 4 that is the image acquisition position by driving the drive motor 35 and causing the traveling wheels 34 to travel along the two rails 33. In this state, the measurement unit (gantry) 2a of the CT apparatus 2 is set as an affected area, and CT imaging is performed (step S6).

  The CT image acquired by the CT imaging is compared with the CT image (reference image) acquired in the treatment room 14 in advance, and the displacement amount of the affected part position is calculated (step S8). Then, the shift amount is transmitted to the treatment bed 4, and the patient is aligned by moving the treatment bed 4 by the shift amount (3D-3D positioning) (step S10).

  When the X-ray imaging apparatus 3 is performed in step S5, the FPD driving mechanisms 7a and 7b attached to the ceiling 9 are operated to set the FPDs 6a and 6b at predetermined positions. Then, the patient is irradiated with X-rays from the X-ray tubes 5a and 5b installed under the floor 19 to acquire bi-directional in-vivo fluoroscopic images (step S7).

  The acquired X-ray fluoroscopic image is compared with a DRR image (reference image) created in advance, and the displacement amount of the affected part position is calculated (step S9). Then, the shift amount is transmitted to the treatment bed 4, and the patient is aligned by moving the treatment bed 4 by the shift amount (2D-2D positioning) (step S10).

  After completing the patient positioning, the measuring unit 2a of the CT apparatus 2 is retracted from the affected area, and the irradiation port movable unit 20 is returned to the original position. Then, beam irradiation is started (step S11).

  In step S11, scanning irradiation is performed using the scanning irradiation apparatus 1 by the following method. FIG. 4 is a flowchart showing an example of an irradiation procedure using the scanning irradiation apparatus of one embodiment.

  As shown in FIG. 4, first, the incident energy of the particle beam and the plate thickness in the range shifter 21 are set so that the stop position of the particle beam corresponds to the deepest slice (Z1) of the affected area irradiation region (step S21). .

  Next, the current value of the scanning electromagnet 11 is set so that the beam is irradiated to one point (X1, Y1) in the affected area irradiation area in this slice (step S22). When the setting of the beam position (X1, Y1, Z1) is completed, the irradiation control device (not shown) outputs a command signal to the beam emission control device, and the beam is emitted to start irradiation (step S23).

  In the irradiation control device, doses (preset values) to be irradiated to the respective positions are obtained in advance. When the dose measurement value of the first point (X1, Y1, Z1) output from the dose monitor 32 reaches a preset value, the irradiation control device outputs a current switching command signal to the power source of the scanning electromagnet 11, and the next point The beam position is changed to (X2, Y2, Z1) (step S24).

  Here, the irradiation method in which the beam emission is temporarily stopped after the irradiation control device outputs the current switching command signal until the switching completion command signal is received from the power source of the scanning electromagnet 11 is referred to as a spot scanning method. Further, an irradiation method that does not stop the beam emission even while the power source current of the scanning electromagnet 11 is switched is referred to as a raster scanning method.

  Hereinafter, every time the dose measurement value reaches the preset, the current of the power source of the scanning electromagnet 11 is switched. When the final point (XN, YN, Z1) in the slice is reached, the beam emission is stopped and the plate thickness of the range shifter 21 is changed to change to the previous slice position (steps S25, S26). ).

  This time, the current of the scanning magnet is set so that the beam is irradiated to one point (X1, Y1, Z2) in the affected area irradiation area in the next slice. Then, irradiation in the irradiation region is performed in the same manner as in the previous slice.

  In this way, irradiation within the slice is performed sequentially, and a series of irradiation is terminated upon completion of irradiation of all slices (steps S12, S27, and S28).

  In such particle beam therapy, the dose is usually divided into a plurality of doses and irradiated over several days. Since the CT apparatus 2 has a high exposure dose for imaging, it is desirable to perform 3D-3D positioning only for the first time, for example, and to perform 2D-2D positioning using the X-ray imaging apparatus 3 with a relatively low exposure dose from the next time.

  Next, the operation and effect of this embodiment will be described.

  In the scanning irradiation apparatus 1 configured as described above, the irradiation port movable unit 20 located within the movement range of the measurement unit 2a of the CT apparatus 2 is configured to be horizontally movable. For this reason, it is possible to prevent the irradiation port movable unit 20 from interfering with the CT apparatus 2 in advance. That is, CT imaging can be performed at a position where beam irradiation is possible.

  Therefore, unlike the case where the CT apparatus 2 is installed at a location away from the isocenter, it is possible to prevent the deterioration of the positional accuracy due to the significant movement of the treatment bed 4. Therefore, even when the position accuracy of the treatment bed 4 is poor, 3D-3D positioning can be realized.

  Further, unlike the case where the CT apparatus 2 is installed at a location away from the isocenter, the time required for the movement of the treatment bed 4 becomes unnecessary, and 3D-3D positioning can be realized in a short time.

  Furthermore, in the scanning irradiation apparatus 1 configured as described above, it is possible to perform CT imaging for treatment planning in the treatment room 14 and to make a treatment plan in the treatment room 14. At this time, it is possible to shift to the irradiation step without largely moving the treatment bed 4. That is, treatment steps can be shortened, treatment plans can be made and treatment can be started immediately, and treatment time per patient can be greatly shortened.

  Although the position monitor 31 for managing the beam position is required to have position accuracy, it is installed in the irradiation port fixing unit 30 and can therefore ensure the beam position accuracy during beam irradiation.

  The irradiation port movable unit 20 is configured to be movable in the horizontal direction in order to avoid interference with the CT apparatus 2. However, for example, even if it is moved in the vertical direction in FIG. 2, interference with the CT apparatus 2 can be avoided in advance, and the same effect can be obtained.

  Further, when the position monitor 31 is installed at a position far from the isocenter, there is a problem that not only the accuracy of beam position detection is lowered, but also the beam size is expanded due to the influence of scattering by the position monitor 31. For this reason, it is appropriate to fix the position monitor 31 at a distance of 1500 mm or less from the isocenter.

  In general, when the FPD is installed in the irradiation port movable unit 20, it is necessary to retract it at the time of beam irradiation, and the drive mechanism has a dual structure of the port portion and the FPD portion. However, in the present embodiment, the FPDs 6 a and 6 b are suspended from the ceiling 9 and moved to ensure higher positional accuracy than when installed in the irradiation port movable unit 20.

  In this embodiment, when it is acceptable to reduce the image size, the FPDs 6a and 6b do not use a drive mechanism, but are installed using a fixed supporter at a position where interference with the CT apparatus 2 is avoided. May be.

(Modification)
Next, a modification of the embodiment of the scanning irradiation apparatus will be described. In addition, in this modification, the description which overlaps with the said embodiment is abbreviate | omitted.

  Although the irradiation port movable part 20 in the above embodiment is configured to be horizontally movable, the irradiation port movable part of the present modification is configured to be detached from the irradiation port fixing part 30 and moved. The irradiation port movable portion is detachably attached to the irradiation port fixing portion 30 by a fixing means such as a screw. The irradiation port movable part of this modification is located within the movement range of the measurement unit 2 a of the CT apparatus 2, similarly to the irradiation port movable part 20.

  A range shifter 21 and a ridge filter 22 are installed in the irradiation port movable portion of this modification. Therefore, since the irradiation port movable part can be removed from the irradiation port fixing part 30, the range shifter 21 and the ridge filter 22 can be replaced with different types.

  Thus, according to the scanning irradiation apparatus of this modification, it is comprised so that the irradiation port movable part located in the movement range of the measurement part 2a of CT apparatus 2 may be removed and moved. For this reason, it is possible to prevent the irradiation port movable part from interfering with the CT apparatus 2 in advance. In other words, the patient can be positioned using the CT apparatus 2 by removing and moving the irradiation port movable part at the time of CT imaging and attaching it at the time of irradiation.

  In the scanning irradiation apparatus of the present embodiment, slice switching during irradiation is performed by changing the emission energy of the particle beam with an accelerator. Since adjustment of the emission energy is difficult to set a range (range) of 1 mm or less, the depth of the affected area set by the treatment plan, that is, the maximum range is adjusted by the range shifter 21 installed in the irradiation port removal portion. By replacing it with one of appropriate thickness.

  Even with the scanning irradiation apparatus of the present embodiment configured as described above, the same effects as those of the above-described embodiment can be realized.

(Other embodiments)
Although the embodiment of the present invention has been described, this embodiment is presented as an example and is not intended to limit the scope of the invention. This embodiment can be implemented in various other forms, and various omissions, replacements, changes, and combinations can be made without departing from the spirit of the invention. This embodiment and its modifications are included in the scope of the present invention and the gist thereof, and are also included in the invention described in the claims and the equivalent scope thereof.

  In addition, in the said embodiment, although the horizontal fixed type treatment bed 4 is used, it is applicable also to the sitting position irradiation apparatus using the CT apparatus of the vertical scanning system installed in the treatment chair and the ceiling. In this case, the irradiation port movable unit 20 is configured to avoid interference with the measurement unit 2a of the CT apparatus 2 that performs vertical scanning. As the CT apparatus 2, a cone beam CT apparatus may be used.

  Furthermore, in the said embodiment, although all the range shifters 21 as a range adjuster were installed in the irradiation port movable part 20, you may make it install not only this but at least one part.

  DESCRIPTION OF SYMBOLS 1 ... Scanning irradiation apparatus (particle beam irradiation apparatus), 2 ... CT apparatus (other apparatuses), 2a ... Measurement part, 3 ... X-ray imaging apparatus, 4 ... Treatment bed, 5a, 5b ... X-ray tube, 6a, 6b ... FPD, 7a, 7b ... FPD drive mechanism, 8 ... particle beam, 9 ... ceiling, 10 ... irradiation port, 11 ... scanning electromagnet (beam scanning electromagnet), 12 ... vacuum duct, 13 ... decorative wall, 14 ... treatment room , 15 ... ion source, 16 ... linear accelerator, 17 ... synchrotron, 18 ... take-out device, 19 ... below the floor, 20 ... irradiation port movable part, 21 ... range shifter (range adjuster), 22 ... ridge filter, 23 ... reinforcement Frame, 24 ... Rail, 25 ... Roller, 26 ... Cosmetic cover, 30 ... Irradiation port fixing part, 31 ... Position monitor, 32 ... Dose monitor, 33 ... Rail, 34 ... Traveling wheel, 35 ... Drive motor

Claims (4)

A particle beam irradiation device for irradiating a patient's affected area with a particle beam;
A CT apparatus for acquiring a three-dimensional image of the patient in the body;
A particle beam therapy device comprising:
The particle beam irradiation apparatus includes:
A beam scanning electromagnet for two-dimensionally scanning a particle beam;
An irradiation port for irradiating two-dimensionally scanned with the particle beam by the beam scanning magnets to the affected area of the patient,
Have
The irradiation port, possess an irradiation port fixation section having a position monitor for detecting the position of the particle beam, and a movable illumination port movable portion with respect to the irradiation port fixation section,
The irradiation port is set in the vicinity of the CT apparatus and within a moving range when the CT apparatus acquires an image, and the irradiation port is outside the moving range of the CT apparatus when the CT apparatus acquires an image. Thus, the particle beam therapy system characterized in that the irradiation port movable part is movable . The particle beam therapy apparatus according to claim 1, wherein the irradiation port movable unit moves in a horizontal direction with respect to the irradiation port fixing unit. 3. A range adjuster for adjusting the range of the particle beam to the patient is further provided, and at least a part of the range adjuster is mounted on the irradiation port movable part. The particle beam therapy apparatus according to 1 . An imaging method for imaging the in-vivo three-dimensional image by the particle beam therapy system according to claim 1,
An irradiation port moving part moving step of moving the irradiation port moving part outside the moving range of the CT apparatus;
After the irradiation port movable part moving step, a CT device moving step for moving the CT device to an image acquisition position;
After the CT device moving step, an image acquisition step of acquiring a 3D image of the patient in the body using the CT device;
An imaging method using a particle beam therapy system .

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