JP4500964B2 - Brain function diagnostic device - Google Patents

Description

  The present invention relates to a brain function diagnostic apparatus, and relates to an apparatus that can collectively diagnose basic functions to higher cerebral functions.

  Since brain function is the basis of daily family life and social life, early diagnosis is necessary. In addition, since this diagnosis is qualitative and has a large variation among those who make the diagnosis, a quantitative diagnosis as much as possible is also necessary.

As a conventional technique related to a brain function diagnostic apparatus, a description of a brain function diagnostic apparatus that measures higher-order functions of the brain is described in, for example, Patent Document 1 below, and a description of a brain function diagnostic apparatus that uses a centroid shaker is described in, for example, In addition, for example, Non-Patent Document 1 below discloses a technique relating to quantification of the cerebellar function, which is a skillful movement of a finger, and Non-Patent Document 2 below describes a technique relating to quantitative measurement of a speech function.
JP 2004-135824 A JP 2004-180792 A Ichiro Shimoyama et al., “Simple quantification of cerebellar function test by micro computer application-finger tapping test”, Neurologia medico-chirurica, 1983, Vol. 23, No. 6, pages 437-440. Yoshiji Kojima et al., “Clinical Significance of“ Voice On-Off Test ””, Spoken Language Medicine, 1988, Vol. 29, No. 2, pp. 161-167

  However, the examination items are limited to a single item in any of the above-mentioned techniques, and it is necessary to determine whether or not the brain health level is within the normal range for daily life at a plurality of facilities. . This is a heavy burden on people who want to undergo a brain health checkup, and the frequency of measurement decreases due to the magnitude of the burden, and the discovery of brain function disorders is delayed, or it becomes extremely serious. Problems such as the first discovery. Therefore, it is highly desirable for the early detection of the occurrence of a brain function disorder to reduce the burden on the person to be diagnosed by performing a plurality of test items at once in one place.

  Therefore, in view of the above, an object of the present invention is to provide a brain function diagnosis apparatus that can perform various brain function diagnoses at once.

  In order to achieve the above object, the present invention specifically adopts the following means. The present invention examines the basic functions of visual field, hearing, hand skin sensation, speech, and standing position, and reading functions, right-and-left recognition, short-term memory function, skillful movement of fingers, and sophisticated functions of knee flexion and extension. The composition was combined in combination. Specifically, the following means are employed.

  As a first means, an information processing device, a display device and an integration device connected to the information processing device, a right hand input / skin stimulation device, a left hand input / skin stimulation device, and a center of gravity oscillation measurement device connected to the integration device And a brain function diagnostic apparatus having a headphone and a microphone.

  In this means, the right hand input / skin stimulation device has a right hand vibration motor and a right hand input key, and the left hand input / skin stimulation device has a left hand vibration motor and a left hand input key. It is also desirable to place the right hand input key close and the left hand vibration and left hand input key close.

  Also, in this means, the integrated device is connected to the information processing device I / O for inputting / outputting digital signals, the right hand vibration motor and the left hand vibration motor, and connected to at least one of the right hand vibration motor and the left hand vibration motor. A D / A converter that converts a digital signal from the information processing device into an analog signal and outputs the analog signal, a headphone is connected to the D / A converter in the integrated device, and a microphone is an A / A in the integrated device. Connected to D converter, center of gravity fluctuation measuring device connected to A / D converter in integrated device, I / O connected to right hand input key and left hand input key, monitoring on / off It is also desirable to have a configuration that does this.

Further, in this means, the information processing apparatus vibrates the right-hand vibration motor, means for measuring the time from when the signal is output until the input by the right-hand input key is received, and the reference measurement in which the measured time is obtained in advance. Having a storage device storing a program for functioning as means for comparing with time, means for outputting to the display device based on the result of the comparison processing, the headphones have two speakers on the left and right, and The information processing device is a means for outputting sound to one of the two left and right speakers of the headphones, a right hand input key for the right hand input / skin stimulation device corresponding to the speaker that outputs the sound after outputting the sound, or Means for measuring the time until the input with the left hand input key of the left hand input / skin stimulator is received, and the measured time is obtained in advance. Having a storage device storing a program for functioning as a means for performing comparison processing with a certain reference measurement time, a means for outputting to a display device based on a result of the comparison processing, and an information processing device for right-hand input Means for measuring the time between each input when receiving multiple inputs using the key or the left-hand input key, means for performing comparison processing with a reference measurement time determined in advance based on the measured time, and results of comparison processing A storage device that stores a program for functioning as a means for outputting to the display device based on the information processing device; As a means for performing comparison processing with a reference measurement time obtained in advance based on the fluctuation of the center of the sole pressure, and as a means for outputting to a display device based on the result of the comparison processing. Having a memory device program is stored in order to, also desirable.

Further, in this means, the information processing apparatus divides the display screen of the display device into a plurality of regions, and sequentially displays the plurality of determination targets in any of the divided regions, after the determination target is displayed on the display device. Means for measuring time until receiving input from right hand input / skin stimulating device or left hand input / skin stimulating device, and storing together with position information of determination target displayed on display screen of display device, determined as measured time It is also desirable to have a storage device in which a program for functioning as a means for performing comparison processing with symmetrical position information is stored. Thus, the diagnosis subject can input the right hand input / skin stimulation device or the left hand input / skin stimulation device based on the region divided into a plurality of regions, measure the time until the input and input the input. By storing the position information of the original determination target and performing a comparison process, it is possible to quantitatively determine the cognitive function of the visual field in the eye. Here, the determination target is information to be displayed on the display screen of the display device, and information having various shapes having an area such as a circle or a square is desirable. In addition, the position information here refers to position information such as coordinates on the display screen on which the determination target is displayed. Of course, the coordinates themselves are included, but only the information on the divided area where the determination symmetry is displayed is of course included. Good. Further, in this means, it is also desirable that the plurality of divided regions are divided into at least four in the vertical and horizontal directions when viewed by the diagnosis subject. In addition, it is desirable that each of the plurality of divided areas is further divided into two areas, and each of the plurality of divided areas is further divided into a central visual field area and a peripheral visual field area.

  By the above means, it is possible to provide a brain function diagnostic apparatus that can perform various brain function diagnoses at once.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings.

  FIG. 1 is a schematic diagram of a brain function diagnostic apparatus (hereinafter also referred to as “this apparatus”) according to the present embodiment. As shown in FIG. 1, the brain function diagnosis apparatus 1 according to the present embodiment includes an information processing apparatus 2, a display apparatus 3, an integration apparatus 4 connected to the information processing apparatus, and a right-hand input / cum function connected to the integration apparatus 4. It has a skin stimulating device 5, a left hand input / skin stimulating device 6, a center-of-gravity fluctuation measuring device 7, headphones 8, a microphone 9, and a printer 10. This device combines the above devices under the integrated device 4 to provide basic functions for visual field, hearing, hand skin sensation, speech, and standing position, as well as reading comprehension functions, left and right recognition, short-term memory functions, The sophisticated functions of finger skill and knee flexion / extension can be combined as test items, and various brain function diagnoses can be performed at once. In other words, diagnosis of primary functions such as cognitive functions from sensory input from eyes, ears, and palms, motor output function by vocalization, fingers, knees, etc., and eyes to fingers, ears to fingers, palms to fingers, Link function for eye-to-mouth / eye-to-knee movement, that is, secondary diagnosis, and combined functions such as memory, learning, left / right recognition, etc., that is, tertiary diagnosis can be performed. Become.

  The information processing device 2 is connected to the display unit 3, the integration device 4, and the printer 10, displays various information on the display unit 2, and controls each of the devices through the integration device 4. Specific operation and configuration will be described later.

  An input device 201 is connected to the information processing apparatus 2 and accepts a request for starting or stopping diagnosis of brain function. The input device 201 corresponds to a keyboard, a mouse, or the like. The input device 201 has a minimum necessary input, and a person who wants to perform a brain function diagnosis (hereinafter simply referred to as “diagnosis”) (hereinafter simply referred to as “diagnosis”). In order to make it easier to understand, the diagnosis subject should be configured to enter only the left and right push buttons, and the assistant should be able to enter the name and age with only a few buttons. In this way, a device that is easier to use can be realized. It is also possible to adopt a configuration in which this function is also provided in the right hand input / skin stimulation device 5 or the left hand input / skin stimulation device 6 described later.

  The display unit 3 is connected to the information processing apparatus 2 and displays various information on the screen. Examples of the various information include an operation instruction to a person (hereinafter, simply referred to as “diagnostic subject”) who wants to diagnose brain function (hereinafter also simply referred to as “diagnosis”), a result of diagnosis, and the like. As a specific example of the display unit 3, a commercially available display device such as a liquid crystal display device or a CRT (cathode ray tube) display device can be used. In the present embodiment, the input device 201 and the display unit 3 are described as separate units, but a so-called touch panel that can accept an input by touching a predetermined portion of the so-called display unit 201 can also be used. .

  The integration device 4 is connected to the information processing device 2 via a cable 401, and further connected to a right hand input / skin stimulation device 5, a left hand input / stimulation device 6, a center of gravity fluctuation measurement device 7, a headphone 8, and a microphone 9. ing. The operations of the information processing device 2, the integration device 4, and each of the above devices will be described later. The integration device 4 outputs an excitation signal to each of the above devices based on an instruction from the information processing device 2, and outputs a signal from each device. Operations such as input and output of signals to the information processing apparatus 2 are controlled.

  The printer 10 is connected to the information processing apparatus 2, and prints and displays the diagnosis result on a medium such as paper. As this printer 10, commercially available printers are widely applicable. In addition, the printer 10 can be omitted as a configuration requirement when it is determined that only display by the display unit 3 is sufficient.

  FIG. 2A is a diagram showing an overview of the right-hand input / skin stimulation device 5 in this device. The right hand input / skin stimulating device 5 is arranged so that the right hand can be placed when the diagnosis subject views the display unit 2 from the front, and gives a stimulus such as vibration to the palm of the diagnosis subject. It is possible to input a response in response to a stimulus or the like. Specifically, the right hand input / skin stimulation device 5 includes a housing 501, and a vibration unit 502 and a right hand input key 503 installed in the housing 501. The vibration unit 502 includes a vibration motor 5021 and a pad 5022 that covers the vibration motor 5021 (see FIG. 2B), and the person to be diagnosed places his / her palm on the pad 5022 to remove the vibration from the vibration motor. It is possible to feel vibration. As a result, when the palm placed on the pad 5022 feels vibration, the diagnosis subject can press the right hand input key 503 to transmit his / her reaction to the integration device 4 and the information processing device 2. . Of course, in this case, it is extremely desirable to arrange them close to each other so that the person to be diagnosed can press the right hand input key 503 while placing a palm on the pad 5022.

  The left hand input / skin stimulation device 6 has a housing 601 and a vibration unit 602 left hand input button 603, and the arrangement thereof is designed symmetrically with the right hand input / skin stimulation device 5. The operation of is almost the same. FIG. 3 shows a schematic diagram thereof.

  The center-of-gravity sway measuring device 7 is a device for detecting a fluctuation in the center position of the sole pressure of the diagnostic subject when the diagnostic subject is placed, and includes a mounting plate 701 and a high-sensitivity load cell 702. Is arranged. Specifically, as shown in FIG. 4, a regular triangular mounting plate 701 and three high-sensitivity load cells 702 that support the mounting plate 701 are provided near the apexes of the regular triangle. Has been. The load cell 702 has a strain gauge (or piezoelectric element). The strain gauge (or piezoelectric element) detects a change in stress generated when the sole pressure center position changes on the mounting plate 701, and the change is detected by the foot. This is detected as a change in the bottom pressure center position. Since the center-of-gravity sway measuring device 6 in this device is configured to have three load cells 702, changes in the center of foot sole pressure can be grasped in three dimensions. In this device, it is possible to measure the fluctuation of the center position of the plantar pressure with high accuracy using an equilateral triangle-shaped plate and three load cells. For example, it is only necessary to determine the center position of the plantar pressure in one dimension. If it is determined that the number of load cells is one or two, the shape of the mounting plate and the number of load cells are not particularly limited.

  As shown in FIG. 1, the headphone 8 includes two speakers 801 and a band 802 that spans the two speakers 801, and is fixed to the head of the person to be diagnosed at the time of diagnosis. The sound pressure stimulus is transmitted to the diagnosis subject through the speaker 801. The headphones 8 are not particularly limited as long as sound can be transmitted to the diagnosis subject, and generally used headphones can be used.

  FIG. 5 is a diagram showing the microphone 9 and the head face holder 901 in the present apparatus. Note that the microphone 9 of the present embodiment is configured to be fixed to the head-face holder 901.

  The head-face holder 901 is used to fix the viewing angle of the person to be diagnosed with respect to the display unit 3 during visual field measurement. The head 902 and two support bars 903 extending vertically from the base 902, It has a chin holding part 904 and a forehead holding part 905 spanned between the support bars 903. Further, in this embodiment, since it is necessary to perform diagnosis for only one eye in the diagnosis, the visual field blocking plate 906 is provided so that the forehead holding unit 905 can be moved.

  The microphone 9 is fixed in the vicinity of the mouth of the diagnosis subject by a member 907 extending from the support rod 903 of the head face holding unit 901, recognizes the sound emitted by the diagnosis subject, and outputs the result to the integration device 4. .

  In this apparatus, the microphone 9 is fixed to the head-face holding unit 901 via the member 907. However, the arrangement of the microphone 9 is not limited as long as the sound emitted by the diagnosis subject can be reliably recognized. It is also possible to adopt a configuration in which a member can be attached and installed near the mouth of the person to be diagnosed.

  Next, the operation of this apparatus will be described. FIG. 6 shows a block diagram focusing on the information processing apparatus 2 and the integration apparatus 4 of this apparatus.

  As shown in FIG. 6, the information processing apparatus 2 in this apparatus includes an input device 201 that receives input from a diagnosis target person, an operation system, a program for diagnosis, various reference data serving as a reference for diagnosis, and a diagnosis target person's A storage device 202 that stores measurement results, a CPU 203 that performs calculations, and a RAM 204 that functions as a recording medium and enables high-speed processing and real-time reporting.

  The integrated device 4 includes a digital-analog converter 403 (hereinafter referred to as “D / A converter”) that converts a digital signal into an analog signal and outputs the analog signal, and an analog-digital converter 404 that converts the analog signal into a digital signal and outputs the digital signal. (Hereinafter referred to as “A / D converter”), an I / O 402 that is connected to the D / A converter and the A / D converter and inputs / outputs a digital signal to / from the information processing apparatus 2, and an audio amplifier 405. Have.

  Each of the vibration motors of the vibration parts of the right hand input / skin stimulation device 5 and the left hand input / stimulation device 6 is connected to a D / A converter in the integrated device 4 through a shield line. The information processing apparatus 2 controls the operation of each vibration unit via the I / O and D / A converters. The input keys of the right hand input / stimulation device 5 and the left hand input / stimulation device 6 are each connected to an I / O through a shield line, and the I / O monitors the on / off of the signal to indicate whether there is an input. It can be transmitted to the processing device 2. In this way, data input from the input key can be acquired more quickly, which is more preferable from the viewpoint of improving the accuracy of diagnosis. Of course, connecting the input key and the I / O via the A / D converter can be adopted as another mode. In addition, when the voltage of the signal input to the vibration unit via the D / A converter is not sufficient, it is useful to secure a sufficient voltage by further passing a driver transistor (not shown).

  The center-of-gravity fluctuation measuring device 7 transmits the output from the load cell to the information processing device 2 via the A / D converter and the I / O. Similarly, the output of the microphone 9 is converted from an analog signal corresponding to sound into a digital signal and transmitted to the information processing apparatus 2 via an A / D converter and I / O. An audio amplifier is provided as a preferred mode between the microphone 9 and the A / D converter, and a more accurate diagnosis is possible by amplifying the audio.

  The headphone 8 is connected to the D / A converter and the I / O of the integrated device 4 in the same manner as the vibration unit of the right hand input / skin stimulating device 5 described above.

  With this configuration, the present apparatus can collectively perform brain function diagnosis covering a large number of items.

  Next, the measurement using this apparatus is demonstrated using the flow of FIG. This flow shows an outline of steps executed after a program stored in the storage device 202 of the information processing apparatus 2 (hereinafter also referred to as “this program”) is read into the RAM.

  This program accepts an input from the input device 201 and starts processing. First, the attribute of the person to be diagnosed is determined (step 01, hereinafter referred to as “S01”). Various data can be adopted as the attribute here, and for example, sex, age, name, weight, height, dominant hand, etc. are applicable. Further, in this step, the display unit 2 is caused to display as shown in FIG. 8 so as to receive an input from the diagnosis subject. The received attribute information is stored in the RAM 204 or a partial area of the storage device 202 as attribute data. If weight and height are used as attributes, it is useful in that it can normalize the fluctuation of the center of gravity and perform diagnostic processing. If a dominant hand is used as an attribute, normalization is performed for repeated finger movements. It is useful in that it becomes possible.

  Next, this program performs diagnostic processing by controlling each of the devices connected to the integrated device 4 (see FIG. 7 again, S02). In this embodiment, since there are a plurality of items of diagnostic processing, which device is used in which order can be adjusted as appropriate. The diagnostic processing in each device will be described later.

  Then, after performing the diagnostic process in each device, it is determined whether or not the necessary brain function diagnosis process has been completed (S03), and if completed, each diagnosis target person obtained by the diagnostic process using each device is determined. Processing for displaying the diagnostic data on the display unit is performed (S04), and printing is performed using the printer 10 as necessary. The display process includes displaying whether or not an abnormality is recognized for each brain function diagnosis, and the person to be diagnosed can know the state of his / her brain function. In this process, it is useful to output a detailed result of the item to the printer so that it can be useful for the diagnosis subject to be diagnosed by a specialist doctor for an item (brain function) that is determined to require reexamination later. .

  Next, diagnostic processing using each device will be described. First, diagnostic processing using the right hand input / skin stimulation device 5 and the left hand input / skin stimulation device 6 will be described. FIG. 9 is a diagram showing a flow of diagnostic processing using the right hand input / skin stimulation device 5 and the left hand input / skin stimulation device 6. This diagnosis process is a test of the cerebellum by finger tapping test, specifically, it is judged whether the cerebellum is functioning in the range of natural aging by causing the fingers to repeatedly move. is there. As a diagnostic method, the right hand input key 503 of the right hand input / skin stimulation device 5 or the left hand input key 603 of the left hand input / skin stimulation device 6 (hereinafter simply “ (Also referred to as “input key”), and the average value and standard deviation of the time interval of the input key struck by the person to be diagnosed are obtained (measurement data acquisition, S0202), and compared with cerebellar examination reference data obtained in advance. It is determined whether or not the function of the cerebellum is within a predetermined range (normal range) (comparison process, S0203). Cerebellar examination reference data obtained in advance is data obtained from a large number of people who are judged to have normal cerebellar function, and is created for each attribute required for diagnosis, and the time interval at which the input key is tapped Is the data in which the mean value and the standard deviation are related to age. Of course, even if the attributes are different, the same reference data can be used for attributes that are not necessary for diagnosis. Prior to inputting the input key, it is useful to display an explanation of the operation on the display device (operation explanation display, S0201).

  Further, another diagnosis process using the right hand input / skin stimulation device 5 and the left hand input / skin stimulation device 6 will be specifically described with reference to FIGS. This diagnosis process is a process for diagnosing the visual function according to the visual field of the brain. Specifically, in response to the display on the display device 3, the right hand input / skin stimulation device 5 or the left hand input / skin stimulation device 6 is input. The diagnostic process is performed by. The processing flow in this diagnosis processing is the same as that in FIG. However, the contents of the operation explanation, the contents of measurement data acquisition, and the contents of the comparison process are different. FIG. 10 is a diagram showing an example of a screen displayed on the display device 3 in this diagnostic processing, and FIG. 11 is a diagram showing an example of a diagnostic result in this diagnostic processing.

  Prior to this diagnosis process, the person to be diagnosed applies his / her chin to the chin holder 904 and his forehead to the forehead holder 905 to fix the head to the head / face holder 901 and fix the viewing angle. At the same time, the visual field shielding plate 906 limits the visual field of one eye of the diagnosis subject. The person to be diagnosed determines and operates the display on the display device 3 with only one eye.

  FIG. 10 shows an example 1001 displayed on the screen by the display device 3 during the measurement data acquisition process. As shown in FIG. 10A, first, in this process, vertical lines 1003 and horizontal lines 1004 are displayed in the screen 1002 of the display device 3, and the screen 1002 is displayed in the upper right area 1005, lower right area 1006, lower left area 1007, The upper left area 1008 is divided into four areas, and the determination objects 1009 are displayed one by one in the four areas in random order (FIG. 10B shows a case where the determination object 1009 is in another area). As will be described later, in this diagnosis process, a central visual field region 1011 is formed around the intersection 1010 between the vertical axis 1003 and the horizontal axis 1004 in order to make a determination by distinguishing between the reaction time in the central visual field of the eye and the reaction time in the peripheral visual field. Furthermore, the determination target 1009 is displayed while distinguishing between the inside and outside of the central visual field area 1011 (an area other than the central visual field area is also referred to as a peripheral visual field area). That is, display is performed randomly for a total of eight areas. The central visual field is determined on the basis of the display screen of the display device—the distance of the eye of the diagnostic subject and the central visual angle of the diagnostic subject, and the display device is displayed in the central visual field of the diagnostic subject during the diagnosis process. It is desirable that the size is such that the central visual field region in the display screen 3 can enter. For example, it is considered that the angle of the human central visual field is about 4 degrees or less, and if the distance between the eye of the person to be diagnosed and the display device is 45 cm, a circle with a radius of about 3 cm can be obtained. . As is clear from the above-described operation, in the display of the operation description prior to the measurement of the reaction time, when the determination target 1009 appears on the right side of the display screen of the display device, the input key of the right hand input / skin stimulation device is displayed on the left side. When it appears, an explanation prompting the user to press the input key of the left hand input / skin stimulation device is displayed. As a result, the person to be diagnosed can determine the visual field recognition function of the eight regions while only selecting the right or left.

  Then, the person to be diagnosed pays attention to the intersection 1010 of the vertical line 1003 and the horizontal line 1004, and the right-side area (the upper right area 105 or the lower right area 1006) among the areas where the sequentially displayed determination objects 1009 are partitioned by the vertical line 1003. ) Is pressed, the input key of the right hand input / skin stimulation device 5 is pressed, and when displayed in the left area (lower left region 1007 or upper left region 1008), the input key of the left hand input / skin stimulation device 6 is pressed. . By performing this operation for both the left and right eyes, the program can measure the time (reaction time) required for input from the display on the display device to the input key and determine the cognitive function in the visual field. In this diagnosis process, there is a case where the person to be diagnosed cannot recognize the determination target 1009 in a part of the area and there is no input from the right hand input / skin stimulation device 5 or the left hand input / skin stimulation device 6. In this case, it is still useful to move to the next processing after a certain time has elapsed.

  FIG. 11 shows a display example of the result of the comparison process in this diagnosis. In this process, as shown in FIG. 11, the average values of the reaction times measured in the central visual field and the peripheral visual field in each region of the right eye and the left eye are displayed, and based on this result, there is an abnormality in the perceived cognitive function. It becomes possible to determine whether or not. For example, if the reaction time of the right upper right peripheral field of the right eye and the right upper right peripheral field of the left eye is extremely slow compared to other peripheral and central visual fields, a detailed examination should be performed on the display result as it is suspected that cognitive deterioration has occurred. Display can be performed. Thereby, in this process, the state of the central visual field and the peripheral visual field can be checked very easily, and this determination can be made quantitatively. That is, since the reaction time can be determined quantitatively, it can be detected as an abnormality in the reaction time earlier than the stage where the person to be diagnosed feels an abnormality, and an accurate early diagnosis is possible. Note that the result of the comparison process shown in FIG. 11 is used only in the information processing apparatus and is not displayed to the person to be diagnosed. If it is determined that a further examination is necessary, it is determined as electronic data by a specialist. It is also useful to store it in a recording medium in the information device so that it can be left. The determination of how long the reaction time is late can be adjusted as appropriate due to the influence of age, etc., but if it is too slow compared to the values in other areas, it is appropriate to determine that the examination is necessary It is.

  Further, diagnostic processing using another right hand input / skin stimulation device 5 and left hand input / skin stimulation device 6 will be described. In this diagnosis process, a vibration is applied to the palm, and the reaction is examined to determine whether or not there is a disturbance in the vibration sense of the palm. The process flow in this diagnosis process is the same as that in FIG. 9 described above. However, the contents of the operation explanation, the contents of measurement data acquisition, and the contents of the comparison process are different. As a diagnostic method, the palm of the subject to be diagnosed was placed on the pad 5022 of the vibration unit 502 of the right-hand input / stimulator 5, the vibration motor 5021 was vibrated to stimulate the subject to be diagnosed, and the stimulus was felt If the right hand input key 503 is tapped, the time until the reaction (reaction time) is obtained, and compared with the reaction time reference data obtained in advance, whether the function related to the vibration sense of the palm is within the normal range. Determine whether. The reaction time reference data is data obtained in advance from a large number of persons having normal palm vibration sensation, and is created for each attribute necessary for diagnosis, and is data in which reaction time and age are related.

Next, diagnostic processing using the center-of-gravity fluctuation measuring device 7 will also be described. In this diagnosis process, the posture maintenance function is diagnosed by standing up on the triangular mounting plate 701 and examining the center of the sole pressure. The processing flow in this diagnosis process is the same as that in FIG. 9 described above, but the contents of the operation explanation, the contents of measurement data acquisition, and the contents of the comparison process are different. As a diagnostic method, stop as much as possible in a short period of time, determine the fluctuation of the center of foot pressure in that case, and compare it with the pre-determined test reference data to determine whether the posture maintenance function is within the normal range. to decide. Here, the inspection standard data is data obtained in advance from a large number of persons having a normal posture maintaining function. For example, as shown in the graph of FIG. This corresponds to the predicted value of the size of. Note that FIG. 12 also shows the distribution in the case of actual measurement (“Y” in the figure indicates the actual measurement value, for example, what is indicated by an arrow in the figure is necessary. (This is a value that is considered a caution). In this case, the “swing of the center of the plantar pressure” corresponds to the amount of energy calculated based on the waveform obtained by recognizing a change in the center of gravity obtained from a plurality of load cells as a waveform.
Further, in this embodiment, in order to instruct the diagnosis subject to stand up and bend and stretch on the center-of-gravity sway measurement device, it is useful to display an appropriate instruction on the display device when acquiring measurement data.

  Next, the diagnosis process using the headphones 8 will also be referred to. This diagnosis process uses a sound stimulus and examines the hearing by obtaining a response time to the stimulus. The processing flow in this diagnosis process is the same as that in FIG. 9 described above, but the contents of the operation explanation, the contents of measurement data acquisition, and the contents of the comparison process are different. As a diagnosis method, for example, when a plurality of types of sound pressure calibrated sounds are prepared, a headphone 8 is attached to a person to be diagnosed, sound is randomly output to either of the left and right speakers of the headphone 8, and the output is recognized. This is done by measuring the time (reaction time) until the person to be diagnosed inputs to the input key (presses the key). Then, this reaction time is obtained and compared with previously obtained examination reference data to determine whether or not the hearing function is within a normal range. The sound pressure calibrated sound is not particularly limited as long as the above measurement is possible, but using a click sound that holds a wide range of frequency components has an advantage in speeding up the measurement, and a specific frequency component can be used. When the pure tone which has is used, there exists an advantage that the characteristic of the diagnostic subject for every frequency can be investigated more correctly.

  Next, reference will also be made to diagnostic processing using the microphone 9. In this diagnosis process, the person to be diagnosed speaks, and brain function is diagnosed based on the utterance. Specifically, it is determined whether or not a spastic paralytic dysarthria or ataxic dysarthria falls. The processing flow in this diagnosis process is the same as that in FIG. 9 described above, but the contents of the operation explanation, the contents of measurement data acquisition, and the contents of the comparison process are different. As a diagnostic method, words such as “pa”, “ta”, “ka” are continuously uttered as fast as possible, the sound is detected by the microphone 9, and the rise and fall times of the sound signal are obtained, The speech interval and its variation coefficient, the speech interval and its variation coefficient are obtained and compared with previously obtained disease example test reference data to determine whether or not the speech function is within a normal range.

  Then, after making all diagnoses for each of the above devices, comprehensive judgment processing of various judgments is performed. The result is displayed on the display unit 2.

  The result of this measurement is printed on a medium such as paper by the printer 10. The person to be diagnosed can hold his or her own diagnosis result by referring to this result, which can be used for the subsequent treatment. At this time, it is desirable to store the results of each diagnosis process in the storage device 202 in the information processing apparatus 2 so as to be useful for later treatment diagnosis.

  As described above, according to the present embodiment, the diagnostic apparatus can be made compact, and it is possible to provide a brain function diagnostic apparatus that can perform various brain function diagnoses at once.

  In addition, the brain function diagnosis and measurement apparatus according to the present embodiment integrates the control of each apparatus via the integrated apparatus 4 and can be made compact, and can be transported in a portable manner. It can be installed in public facilities such as reception areas, health checkups at local governments, group screenings at companies, and health entertainment facilities such as nursing homes where elderly people gather. In particular, remote medical treatment can be performed by installing this device in a sparsely populated area, connecting it through an electric communication line such as the Internet, and performing various brain function diagnoses.

Schematic of this device. The perspective view schematic diagram of the right hand input and skin stimulation device. The perspective view schematic diagram of the left hand input and skin stimulation device. The perspective outline figure of a gravity center shaking meter. The schematic diagram which shows a microphone and a head face holder. The block diagram of this apparatus. The figure which shows the flow of the diagnostic process in this apparatus. The figure which shows the display of a display apparatus at the time of receiving an input prior to the process start of this apparatus. The figure which shows the flow of the diagnostic process in this apparatus. The figure which shows the example which a display device displays on a screen The figure which shows the example of a display of the result in a comparison process The figure which shows the implementation inspection standard data in the diagnostic process using a gravity center fluctuation measuring apparatus.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Brain function diagnostic apparatus, 2 ... Information processing apparatus, 3 ... Display apparatus, 4 ... Integration apparatus, 5 ... Right hand input and skin stimulation apparatus, 6 ... Left hand input and skin stimulation apparatus, 7 ... Measuring apparatus like gravity DESCRIPTION OF SYMBOLS 8 ... Headphone, 9 ... Microphone, 10 ... Printer, 201 ... Input device, 202 ... Storage device, 203 ... CPU, 204 ... RAM, 401 ... Cable, 402 ... I / O, 403 ... D / A converter, 404 ... A / D converter, 405 ... voice amplifier, 501 ... housing, 502 ... vibrating part, 503 ... right hand input key, 5021 ... vibration motor, 5022 ... pad, 601 ... housing, 602 ... vibrating part, 603 ... left hand input key , 701 ... Loading plate, 702 ... Load cell, 801 ... Speaker, 802 ... Band, 901 ... Head face holder, 902 ... Stand, 903 ... Support bar, 904 ... Jaw holder 905 ... forehead holder, 906 ... field blocking plate

Claims (16)

  Information processing device, display device and integration device connected to the information processing device, right hand input / skin stimulation device, left hand input / skin stimulation device, center of gravity fluctuation measurement device, headphones and microphone connected to the integration device And a brain function diagnostic apparatus.   The right-hand input / skin stimulation device has a right-hand vibration motor and a right-hand input key, and the left-hand input / skin stimulation device has a right-hand vibration motor and a left-hand input key. Item 1. A brain function diagnostic apparatus according to Item 1.   3. The brain function diagnosis apparatus according to claim 2, wherein the right hand vibration and the right hand input key are arranged close to each other.   3. The brain function diagnosis apparatus according to claim 2, wherein the left-hand vibration and the left-hand input key are arranged close to each other.   The integrated device is connected to the I / O for inputting / outputting digital signals to / from the information processing device, the vibration motor for the right hand and the vibration motor for the left hand, and at least of the vibration motor for the right hand and the vibration motor for the left hand 3. The brain function diagnostic apparatus according to claim 2, further comprising: a D / A converter that converts a digital signal from the information processing apparatus into an analog signal and outputs the analog signal.   The brain function diagnosis apparatus according to claim 5, wherein the headphones are connected to the D / A converter in the integrated apparatus.   6. The brain function diagnostic apparatus according to claim 5, wherein the microphone and the audio amplifier are connected to the A / D converter in the integrated apparatus.   6. The brain function diagnosis apparatus according to claim 5, wherein the center-of-gravity fluctuation measuring apparatus is connected to an A / D converter in the integrated apparatus. The information processing apparatus includes:
Means for vibrating the right-hand vibration motor, means for measuring the time from when the signal is output until the input from the right-hand input key is received, means for comparing the measured time with a predetermined reference measurement time 3. The brain function diagnosis apparatus according to claim 2, further comprising a storage device in which a program for functioning as a means for outputting to a display device based on a result of the comparison processing is stored. The headphone has two left and right speakers, and the information processing apparatus corresponds to a means for outputting sound to one of the two left and right speakers of the headphone, and the speaker that outputs the sound after outputting the sound. Means for measuring the time until the input by the right hand input key of the right hand input / skin stimulating device or the left hand input key of the left hand input / skin stimulating device is received, and obtaining the measured time in advance 3. A storage device storing a program for functioning as means for performing comparison processing with a certain reference measurement time, and means for outputting to a display device based on a result of the comparison processing. Brain function diagnostic device.   The information processing device, when receiving a plurality of inputs by the right hand input key or the left hand input key, means for measuring the time between each input, a reference measurement obtained in advance based on the measured time 3. The brain function according to claim 2, further comprising: a storage device storing a program for functioning as means for comparing with time, and means for outputting to a display device based on a result of the comparison processing. Diagnostic device. The information processing apparatus includes: means for obtaining a fluctuation of the sole pressure center from the output of the center-of-gravity fluctuation measurement apparatus; means for performing a comparison process with a reference measurement time obtained in advance based on the obtained fluctuation of the sole pressure center; 3. The brain function diagnosis apparatus according to claim 2, further comprising a storage device that stores a program for causing the display device to function as an output unit based on a result of the comparison process.   The information processing device is configured to divide a display screen of the display device into a plurality of regions, and to sequentially display a plurality of determination targets in any of the divided regions, Means for measuring a time until an input from a right hand input / skin stimulating device or a left hand input / skin stimulating device is received, and storing the time together with position information of a determination target displayed on the display screen of the display device, the measured time The brain function diagnosis apparatus according to claim 2, further comprising a storage device that stores a program for functioning as means for comparing the position information of the determination target with the position information of the determination target.   14. The brain function diagnosis apparatus according to claim 13, wherein the plurality of divided areas are divided into at least four parts in the vertical and horizontal directions when viewed by a person to be diagnosed.   The brain function diagnosis apparatus according to claim 14, wherein each of the plurality of divided areas is further divided into two areas. The brain function diagnosis apparatus according to claim 14, wherein each of the plurality of divided areas is further divided into a central visual field area and a peripheral visual field area.