JP4452824B2 - Arterial blood vessel detection device, blood pressure measurement device, and pressure pulse wave detection device - Google Patents

Description

  The present invention relates to an arterial blood vessel detection device for detecting an artery under the skin using light emitted from an optical sensor, and in the process of changing the pressing force of a pressing member that presses the artery from above the skin. Blood pressure measuring device for measuring blood pressure based on a change in pulse wave represented by secondary light (that is, reflected light or scattered light) reflected or scattered in living tissue such as an artery, and the arterial blood vessel detection device The present invention relates to a pressure pulse wave detection device that determines an arterial position and detects a pressure pulse wave.

For diagnosis of cardiovascular function, it is widely performed to detect an artery in a living body and measure the pressure of the artery, that is, the blood pressure, or measure the pressure pulse wave from the artery. For example, in the pressure pulse wave detection device described in Patent Document 1, when the artery is pressed by a pressing surface in which a large number of pressure detection elements (sensor arrays) are embedded, the pressure detection element that outputs the largest signal is the optimal position. The pressure pulse wave detected by the pressure detection element at the optimum position is output.
Japanese Utility Model Publication No. 05-020709

  However, in the pressure pulse wave detection device having a pressing surface in which a large number of pressure detection elements are embedded as described above, a photobridge (bridge) including a pressure sensitive resistor is pressure-detected by heavily using photolithography on a semiconductor substrate. Since advanced processing and measurement techniques for configuring each element are required, the cost increases.

  The present invention has been made in the background of the above circumstances, and an object of the present invention is to provide an arterial blood vessel detection device that can easily and highly accurately detect a blood vessel position of a subcutaneous artery, and has a simple and low structure. An object of the present invention is to provide a blood pressure measurement device capable of reducing costs and a pressure pulse wave detection device capable of measuring a pressure pulse wave with a simple structure and high accuracy.

  A first invention for achieving the above object has a main body mounted on the skin of a living body, and the main body emits light of a predetermined wavelength from the skin toward the artery in the living body. Two light receiving elements disposed at an equal distance from the light emitting element with the light emitting element sandwiched therebetween in order to receive light generated by reflection or scattering of light emitted from the light emitting element in the living tissue , And two pressure sensor devices, and a pressure member that is disposed between the two light sensor devices and variably presses the skin of the living body. .

  According to a second invention, in the arterial blood vessel detection device according to the first invention, as the light emitting element, a first wavelength light emitting element that emits light having a center wavelength within a range of 530 nm to 570 nm, and red light or near infrared light. And a second wavelength light emitting element that emits light.

  According to a third aspect of the present invention, in the arterial blood vessel detection device according to the first or second aspect, an orthogonal direction moving device that translates the main body in a direction orthogonal to the arrangement direction of the two photosensor devices and the pressing member; A rotating device that rotates the main body in a plane including the main body, and is detected by a pair of light receiving elements respectively provided in the two photosensor devices by the orthogonal direction moving device and the rotating device. The main bodies are positioned so that the pulse wave intensities are the same and the respective intensities are maximized.

  4th invention has a main body mounted | worn on the skin of a biological body, The main body is arrange | positioned between two optical sensor apparatuses and the two optical sensor apparatuses, and presses the said biological body skin in a variable pressure The light sensor device includes a plurality of light emitting elements that emit light of a predetermined wavelength from the skin toward the in-vivo artery in the arrangement direction of the two light sensor devices and the pressure member. The light-receiving elements are arranged in a row in a direction perpendicular to the light-emitting elements, and light-receiving elements for receiving light generated by reflection or scattering of light emitted from the light-emitting elements in the living tissue are provided. This is an arterial blood vessel detection device.

  A fifth invention is an arterial blood vessel detection device according to the fourth invention, wherein a plurality of light emitting control means for sequentially emitting light from a plurality of light emitting elements arranged in a line in each of the two optical sensor devices, and a plurality of light emitting control means. Based on comparing the directions of the plurality of pulse waves detected by the light receiving element when the light emitting elements are sequentially emitted, or comparing the magnitudes of the plurality of pulse waves with each other, And an artery position determining means for determining the position of the artery under the other optical sensor device and the position of the artery under the other optical sensor device.

    A sixth invention is the arterial blood vessel detection device according to the fifth invention, wherein the main body is translated in a direction perpendicular to the arrangement direction of the two photosensor devices and the pressing member, A rotating device that rotates a main body in a plane including the main body, and a plurality of light emitting elements arranged in a line in each of the two photosensor devices in the arterial position determining means, After the coarse adjustment of the position of the main body using the orthogonal direction moving device and the rotating device so that the position of the artery is determined, the signal from the light emitting element at the center of the array detected by the light receiving element It further includes optimum body position control means for finely adjusting the position of the body so as to maximize the strength.

  A seventh invention is a blood pressure measurement device for measuring a blood pressure value of a living body, and the arterial blood vessel detection device according to any one of the first to sixth inventions and the pressing force of the pressing member of the arterial blood vessel detection device are continuous. The pulse wave intensity sequentially detected by the light receiving element provided in the optical sensor device located downstream of the artery among the two optical sensor devices is changed to a predetermined state in the process of being changed to And a systolic blood pressure value determining means for determining the systolic blood pressure value of the living body based on the pressing force of the pressing member when it becomes.

  According to an eighth aspect of the present invention, in the blood pressure measurement device according to the seventh aspect of the present invention, in the process in which the maximum blood pressure value determining means continuously changes the pressing force of the pressing member of the arterial blood vessel detection device, When the pulse wave intensity sequentially detected by the light receiving element provided in the optical sensor device located downstream of the artery exceeds a predetermined range having a preset judgment reference value close to 0 as a boundary The maximum blood pressure value of the living body is determined based on the pressing force of the pressing member.

  A ninth invention is the blood pressure measurement device according to the seventh or eighth invention, wherein the light receiving element provided in one of the optical sensor devices in the process of continuously changing the pressing force of the pressing member of the arterial blood vessel detection device Is compared with the pulse waveform detected by the light receiving element provided in the other optical sensor device, and the pressing force of the pressing member when the lower shapes of the two pulse waveforms are substantially equal And further comprising a minimum blood pressure value determining means for determining a minimum blood pressure value of the living body.

  A tenth aspect of the present invention is a pressure pulse wave detection device for detecting a pressure pulse wave from a living body, which has the blood pressure measurement device according to the ninth aspect and is provided on a pressing surface of the pressing member included in the blood pressure measurement device. A pressure detecting element for detecting a pressure pulse wave from the living body, and an average blood pressure value is determined based on a maximum blood pressure value and a minimum blood pressure value determined by the blood pressure measuring device, and the pressure pulse wave is continuously detected. Therefore, it further includes optimum pressing force control means for maintaining the pressing force of the pressing member at the average blood pressure value.

  According to the first invention, in the optical sensor device, the two light receiving elements for receiving the light generated by the light emitted from the light emitting elements being reflected or scattered in the living tissue emit light with the light emitting elements sandwiched therebetween. Since it is provided at an equal distance from the element, when the positioning operation of the optical sensor device is performed so that the intensity of light detected by the two light receiving elements becomes equal, the light emitting element of the optical sensor device is positioned directly above the artery . If this positioning operation is performed for each of the two optical sensor devices, an artery in a certain section can be easily detected. Moreover, since the pressing member is arrange | positioned between two optical sensor apparatuses, it can press an artery reliably.

  According to the second invention, a first wavelength light emitting element that emits light having a wavelength of 530 nm to 570 nm and a second wavelength light emitting element that emits red light or near infrared light are provided, and the light source has a wavelength of 530 nm to 570 nm. When the first wavelength light emitting element that emits light of a wavelength is located near the artery, the pulse wave represented by the secondary light reflected or scattered in the living tissue is red light or near red When external light is reflected or scattered in the living tissue, the pulse wave is inverted, but when the first wavelength light emitting element is not near the artery, the pulse wave represented by the secondary light is red. Since the pulse wave represented by the secondary light of the light emitted from the first wavelength light emitting element is not inverted with respect to the pulse wave represented by the secondary light of the light or near infrared light, the pulse wave represented by the secondary light of the light emitted from the first wavelength light emitting element By positioning so as to be inverted with respect to the pulse wave represented by the next light, the first wavelength is generated. Elements so as to be located on top of the artery can be roughly adjusted position of the arterial blood vessel detection device.

  According to the third invention, the main body for making the pulse wave intensities detected by the pair of light receiving elements respectively provided in the two photosensor devices the same, and maximizing the intensity of each. Can be moved automatically.

  According to the fourth invention, the two photosensor devices each have the light emitting elements arranged in a line, and receive light generated by reflection or scattering of light emitted from the light emitting elements in the living tissue. When the main body is mounted on the skin so that the arrangement direction of the light emitting elements intersects with the artery, the light receiving elements are arranged when the light emitting elements arranged in a row are sequentially emitted. Comparing a plurality of detected pulse waves, the pulse wave from the light emitting element directly above or close to the artery is inverted with respect to the pulse waves from a number of light emitting elements distant from the upper part of the artery, Since the magnitude of the pulse wave is larger than that of the other pulse waves, the arteries under one of the optical sensor devices can be compared by comparing the directions of the plurality of pulse waves or the magnitudes of the pulse waves detected by the light receiving element. Position and other The approximate position of the artery under the optical sensor device can be determined, and the determination of the approximate position of the artery only needs to cause a plurality of light emitting elements arranged in a row to emit light once, Can be done quickly. In addition, since the approximate position of the artery can be determined quickly, the main body can be quickly positioned at an appropriate position. Furthermore, by determining the positions of the two optical sensor devices to be appropriate positions, the pressing member disposed between the two optical sensor devices can also reliably press the artery.

  According to the fifth aspect, the light emission control means and the arterial position determining means can automatically determine the position of the artery under one of the optical sensor devices and the approximate position of the artery under the other optical sensor device.

  According to the sixth aspect of the present invention, the main body is automatically moved by the optimum main body position control means so that the artery is located below the center of the main body.

In the seventh and eighth inventions, there are a case where the pressing force is continuously increased and a case where the pressing force is once decreased to a value higher than the maximum blood pressure value and then continuously decreased. When the pressing force is continuously increased, the lower limit value of the predetermined range becomes the determination reference value, and after the pressing force is once increased to a value higher than the maximum blood pressure value, it is continuously decreased. In this case, the upper limit value of the predetermined range becomes the determination reference value.
Then, when the pressing force of the pressing member is continuously increased, the intensity of the pulse wave detected by the light receiving element provided in the downstream optical sensor device decreases as the pressing force increases, If the pressing force is equal to or higher than the maximum blood pressure value of the artery under the skin and the blood flow is blocked, the blood flow disappears downstream of the blocking site, so the pulse wave intensity becomes extremely small, Since the pulse wave intensity falls below the predetermined range, the maximum blood pressure value can be determined based on the pressing force at that time. On the other hand, when the pressing force is once increased to a value higher than the maximum blood pressure value and then continuously decreased, the blood flow is blocked at the beginning of the pressing force reduction, so the downstream optical sensor The intensity of the pulse wave detected by the light receiving element provided in the device is very small, but the pressure is equal to or lower than the maximum blood pressure value of the artery under the skin, and blood flow resumes in the artery. Then, since the pulse wave intensity increases and becomes higher than the predetermined range, the maximum blood pressure value can be determined based on the pressing force at that time.

  According to the ninth invention, the pressing force of the pressing member is continuously changed in a range including the minimum blood pressure value of the artery pressed by the pressing member, but the pressing force of the pressing member is the minimum blood pressure value of the artery. If the pressure is lower than that, the arterial blood flow is hardly reduced by the pressing of the pressing member, so the shape of the pulse wave detected by the upstream light receiving element and the pulse wave detected by the downstream light receiving element However, when the pressing force of the pressing member is higher than the minimum blood pressure value of the artery, the signal detected by the downstream light receiving element during the period when the pressing force of the pressing member is higher than the arterial pressure. Therefore, the pulse wave detected by the downstream light receiving element is shaped as if the lower part was cut off. Therefore, the lower part of the pulse wave detected by the upstream light receiving element and the downstream light receiving element Check by element Diastolic blood pressure can be determined based on the comparison of the lower shape of the pulse wave.

  According to the tenth invention, the average blood pressure value is determined based on the actually measured maximum blood pressure value and minimum blood pressure value, and the pressing member presses the skin with the average blood pressure value pressing the skin. Since the pressure pulse wave is detected by the pressure detection element provided on the surface, the pressure pulse wave is detected in a state where a part of the arterial blood vessel is almost flattened, so that the pressure in the blood vessel can be reduced with a simple structure. It is possible to continuously detect a pressure pulse wave that accurately represents the pressure pulse wave.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. FIG. 1 and FIG. 2 are main part sectional views in a state where a probe 12 provided in a blood pressure measurement device 10 to which the present invention is applied is attached to an upper arm part 14 of a living body, and FIG. 1 is shown in FIG. 2 is a cross-sectional view perpendicular to the brachial artery 16 cut along line II, and FIG. 2 is a cross-sectional view substantially parallel to the brachial artery 16 cut along line II-II shown in FIG. FIG. 3 is a bottom view of the probe 12. The blood pressure measurement device 10 is a device used for evaluating a cardiovascular system function based on a blood pressure value BP, a pressure pulse wave, and the like, and also has a function as an arterial blood vessel detection device and a pressure pulse wave detection device.

  The probe 12 is attached to the upper arm portion 14 by an attachment band 18. The probe 12 includes a housing 22 having a container shape in which the mounting band 18 is connected and an opening end is in a state of being substantially in contact with the skin 20 of the living body, and the housing 12 accommodated in the housing 22 and via the diaphragm 24. A pressing portion 26 supported so as to be able to enter and exit from the opening, and interposed between the housing 22 and the pressing portion 26 in order to move the pressing portion 26 in a radial direction, that is, a direction perpendicular to the long axis of the brachial artery 16 A pair of bellows 28 and 30 which are actuators are provided. The space between the housing 22 and the diaphragm 24 constitutes a main pressure chamber 31, and air in the main pressure chamber 31 is supplied and exhausted through the pipe 33, whereby the pressure in the main pressure chamber 31. Is adjusted. In FIG. 1, reference numeral 29 denotes a humerus.

  As shown in FIG. 2, the pressing portion 26 includes a case 32 to which the center portion of the diaphragm 24 is fixed, and a main body 34 that is relatively rotatable about the vertical axis C <b> 1 with respect to the case 32. An electric motor 36 provided in the case 32 is provided for driving the main body 34 around the vertical axis C1 to change its angular position, and a male screw 38 fixed to the output shaft of the electric motor 36 is provided. The main body 34 is screwed into a bracket 40 fixed to the main body 34, and the main body 34 is rotated in the horizontal direction according to the rotation of the output shaft. The electric motor 36, the male screw 38, the bracket 40, and the like constitute a rotating device 42.

  The main body 34 has a rectangular substrate 44 with a bracket 40 fixed to the upper surface thereof, and a pressure pulse wave sensor 46 which is fixed to the lower surface of the substrate 44 at the longitudinal center of the substrate 44 and also functions as a pressing member. And two optical sensor devices fixed to the substrate 44 via the bellows rubber 48 on both sides in the longitudinal direction of the substrate 44 so as to sandwich the pressure pulse wave sensor 46, that is, the upstream photosensor device 50 and the downstream photosensor device 52. And.

  The two bellows rubbers 48 constitute an upstream pressure chamber 54 and a downstream pressure chamber 56, respectively, and air in the upstream pressure chamber 54 and the downstream pressure chamber 56 is supplied via pipes 58 and 60. By being discharged, the pressure in the upstream pressure chamber 54 and the downstream pressure chamber 56 is adjusted.

  The upstream side optical sensor device 50 and the downstream side optical sensor device 52 have the same configuration, and as shown in FIG. 3, the pressing surfaces 62 a and b have centers passing through the centers of the two pressing surfaces 62 a and b. The first wavelength light emitting elements 64a and 64b and the second wavelength light emitting elements 66a and 66b that emit light having different wavelengths are disposed on the line C2, and the first wavelength light emitting element 64a is sandwiched between the center lines C2. , B and the second wavelength light emitting elements 66a, 66b, the first light receiving elements 68a, 68b and the second light receiving elements 70a, 70b are arranged so as to be equidistant. A pressure detection element 74 is disposed on the pressing surface 72 of the pressure pulse wave sensor 46 so as to be on the center line C2. That is, the pressure detecting element 74 is disposed between the two optical sensor devices 50 and 52 on a straight line connecting the light emitting element 64a (or 66a) and the light emitting element 64b (or 66b). The wavelength (first wavelength) of light emitted by the first wavelength light emitting elements 64a and 64b is, for example, a wavelength (center of light absorption by biological tissue and blood is 10 times or more that of red light or near infrared light. Wavelength λ = 530 nm to 570 nm, preferably 530 nm to 550 nm). Further, the wavelength (second wavelength) of the light emitted by the second wavelength light emitting elements 66a, 66b is 800 nm, which is a wavelength where the absorption coefficient of oxygenated hemoglobin and the absorption coefficient of oxygen-free hemoglobin are approximately equal, or other Near infrared light wavelength or red wavelength (for example, 650 nm) is used, but when measuring oxygen saturation, it is preferable to use 650 nm.

  FIG. 4 is a block diagram illustrating the overall configuration of the blood pressure measurement device 10. The electronic control unit 80 includes a CPU 82, a ROM 84, a RAM 86, an A / D converter 88, and the like. The CPU 82 uses the temporary storage function of the RAM 86 and executes a program stored in the ROM 84 in advance according to a signal supplied from the operation key 89 or the like, thereby driving and controlling the light emitting elements 64 and 66, A motor drive circuit 92 for driving and controlling the electric motor 36, a main control valve for driving and controlling a main control valve 94 for controlling the pressing force in the main pressure chamber 31, that is, the pressing force by which the pressure pulse wave sensor 46 presses the skin 20. The position control valve drive circuit 100 for driving and controlling the position control valve 98 for controlling the pressure in the drive circuit 96 and the bellows 28 and 30, the pressure in the upstream pressure chamber 54 and the downstream pressure chamber 56, that is, the upstream photosensor device 50. Optical sensor device pressing force control for driving and controlling the optical sensor device pressing force control valve 102 for controlling the pressing force of the downstream optical sensor device 52 Driving circuit 104, and controls the display unit 106.

  The main control valve 94, the position control valve 98, and the optical sensor device pressing force control valve 102 are connected to an air pump 108, and the pressure generated by the air pump 108 is used as a common source pressure. A main control valve 94 and a pressure sensor 110 are connected to the main pressure chamber 31 via the pipe 33, and the upstream pressure chamber 54 is connected to the optical sensor device pressure control valve 102 and the pressure sensor via a pipe 58. 112, and the downstream pressure chamber 56 is connected to the optical sensor device pressing force control valve 102 and the pressure sensor 114 via the pipe 60.

  FIG. 5 is a functional block diagram showing the main part of the control function of the electronic control unit 80. In FIG. 5, the pressure pulse wave sensor pressing force control means 120 drives and controls the main control valve drive circuit 96 while judging the pressure in the main pressure chamber 31 based on the signal supplied from the pressure sensor 110. The pressure in the pressure chamber 31, that is, the pressing force of the pressure pulse wave sensor 46 is controlled. The optical sensor device pressing force control means 122 determines the pressure in the upstream pressure chamber 54 and the pressure in the downstream pressure chamber 56 based on the signals supplied from the pressure sensors 112 and 114, and the optical sensor device pressing force. The control valve drive circuit 104 is driven and controlled to control the pressure in the upstream pressure chamber 54, that is, the pressing force of the upstream photosensor device 50 and the pressure in the downstream pressure chamber 56, that is, the pressing force of the downstream photosensor device 52. .

  When it is determined which one of the first wavelength light emitting element 64 and the second wavelength light emitting element 66 is used, the light emission control means 124 outputs a drive control signal to the LED drive circuit 90, thereby generating upstream light. The light emitting element 64a or 66a on the side determined in the sensor device 50 and the light emitting element 64b or 66b on the side determined in the downstream optical sensor device 52 are caused to emit light at a preset light emission timing, respectively. The light emission timing is determined by the light emitted from the light emitting element 64a or 66a of the upstream side optical sensor device 50 being propagated through the living tissue and detected by the light receiving elements 68a and 70a of the downstream side optical sensor device 52. In order to prevent the light emitted from the light emitting element 64b or 66b of the downstream photosensor device 52 from propagating through the living tissue and being detected by the light receiving elements 68b and 70b of the upstream photosensor device 50, Different frequencies (for example, 2 kHz and 3 kHz) are set, or the same frequency is set so that light is emitted alternately.

  The wavelength selection means 126 determines which one of the first wavelength light emitting element 64 and the second wavelength light emitting element 66 is used for arterial detection and blood pressure measurement. The light emission control means 124 allows the first wavelength light emitting element 64 to be used. And the second wavelength light emitting element 66 emit light, and the signal intensity supplied from at least one of the first light receiving element 68 and the second light receiving element 70 is compared at that time. Select the wavelength used for blood pressure measurement.

  The pulse wave display means 128 separates the signals in accordance with the light emission timing, whereby the pulses derived from the first wavelength and the second wavelength detected by the first light receiving element 68a and the second light receiving element 70a of the upstream optical sensor device 50. Waves and pulse waves derived from the first wavelength and the second wavelength detected by the first light receiving element 68b and the second light receiving element 70b of the downstream side optical sensor device 52 are displayed on the display 106, respectively.

  Since 530 nm to 570 nm are used as the first wavelength and the second wavelength is a wavelength of red light or near infrared light, when the light emitting elements 64 and 66 are above the brachial artery 16, the light receiving elements 68 and 70. The pulse wave derived from the first wavelength detected by the above is inverted with respect to the pulse wave derived from the second wavelength, but when the light emitting elements 64 and 66 are relatively displaced from the upper part of the brachial artery 16, the first The pulse wave derived from the wavelength is not inverted with respect to the pulse wave derived from the second wavelength. 6 to 9 are experimental data showing this. That is, in each of FIGS. 6 to 9, when a light emitting element that emits light having a wavelength of 530 nm, a light emitting element that emits red light (Red), and a light emitting element that emits infrared light (IR) are emitted. FIG. 6 and FIG. 8 show a red light (Red) by positioning a light emitting element that emits light having a wavelength of 530 nm directly above the brachial artery, and FIG. FIG. 7 shows a waveform when a light emitting element and a light emitting element that emits infrared light (IR) are positioned at a position off from just above the brachial artery. FIG. 7 shows a light emitting element that emits red light (Red) and infrared light (IR). 9 shows a waveform when a light-emitting element emitting light is positioned directly above the brachial artery, and a light-emitting element emitting light having a wavelength of 530 nm is positioned away from just above the brachial artery, FIG. 9 emits light having a wavelength of 530 nm Light emitting element, red Emitting element for emitting light (Red), and a light emitting element that emits infrared light (IR), a waveform in the case of is located at a position deviated from all the brachial artery directly. As shown in FIGS. 6 to 9, the backscattered light of red light and infrared light has a downward waveform (a waveform in which the signal intensity decreases as the heart contracts) regardless of the position of the light emitting element. On the other hand, the backscattered light of 530 nm light has an upward waveform (a waveform in which the signal intensity increases as the heart contracts) when the position of the light emitting element is directly above the brachial artery (FIG. 6). 8), when the position of the light emitting element is a position deviated from immediately above the brachial artery, a downward waveform is obtained (FIGS. 7 and 9).

  In addition, since the first light receiving element 68 and the second light receiving element 70 are arranged at the same distance from the light emitting elements 64 and 66, when the light emitting elements 64 and 66 are positioned directly above the brachial artery 16, the first light receiving element The magnitude of the pulse wave detected by 68 is equal to the magnitude of the pulse wave detected by the second light receiving element 70, and the magnitude of each pulse wave is maximized. On the other hand, the difference between the magnitude of the pulse wave detected by the first light receiving element 68 and the magnitude of the pulse wave detected by the second light receiving element 70 increases as the light emitting elements 64 and 66 are displaced from directly above the brachial artery 16. Become. Therefore, when these pulse waves are displayed on the display device 106, it can be determined whether or not the light emitting elements 64 and 66 are positioned directly above the brachial artery 16.

  Therefore, the rough mounting positions of the two photosensor devices 50 and 52 are determined so that the pulse wave derived from the first wavelength is inverted with respect to the pulse wave derived from the second wavelength. Subsequently, when it can be determined that the light emitting elements 64 and 66 are displaced from right above the brachial artery 16, the apparatus operator operates the operation key 89 to move the light emitting elements 64 and 66 directly above the brachial artery 16. Therefore, a signal instructing to move the main body 34 in parallel or rotationally is supplied from the operation key 89. The orthogonal direction movement control means 130 is a control executed when a signal instructing to translate the main body 34 in a direction orthogonal to the brachial artery 16 is supplied. The pressure pulse wave sensor pressing force control means 120 and By reducing the pressing force of the pressure pulse wave sensor 46 and the optical sensor devices 50 and 52 to such an extent that the main body 34 can be moved by the optical sensor device pressing force control means 122, the position control valve drive circuit 100 is driven and controlled. By adjusting the differential pressure between the pair of bellows 28 and 30, the main body 34 is translated in a direction perpendicular to the arrangement direction of the two optical sensor devices 50 and 52 and the pressure pulse wave sensor 46, that is, a direction perpendicular to the center line C2. Thereafter, the pressure pulse wave sensor 46 and the optical sensor devices 50 and 52 are again operated by the pressure pulse wave sensor pressing force control unit 120 and the optical sensor device pressing force control unit 122. The pressing force pulse wave is a predetermined pressing force which is previously set so that detectable. In this embodiment, the orthogonal direction movement control means 130, the position control valve 98, the position control valve drive circuit 100, the pair of bellows 28, 30, etc. constitute an orthogonal direction movement device 131.

  The rotation control means 132 is a control executed when a signal instructing to rotate the main body 34 is supplied. The rotation control means 132 is controlled by the pressure pulse wave sensor pressing force control means 120 and the optical sensor device pressing force control means 122. After weakening the pressing force of the pulse wave sensor 46 and the optical sensor devices 50 and 52 to such an extent that the main body 34 can be moved, the electric motor 36 is rotated by driving the motor drive circuit 92 to horizontally The pulse wave can be detected again by the pressure pulse wave sensor 46 and the optical sensor devices 50 and 52 by the pressure pulse wave sensor pressure control means 120 and the optical sensor device pressure control means 122. A predetermined pressing force preset to a certain degree is used.

The blood pressure value determining unit 134 is a target pressing force set by the pressure pulse wave sensor pressing force control unit 120 so that the pressing force of the pressure pulse wave sensor 46 is higher than a general maximum blood pressure value BP _SYS (for example, 180 mmHg). Then, the pressure of the pressure pulse wave sensor 46 is lowered at a predetermined step-down speed, and the pressure of the pressure pulse wave sensor 46 is increased or decreased by the optical sensor device pressure control means 122. Also, the pressing force of the optical sensor devices 50 and 52 is maintained so that the pressing force of the optical sensor devices 50 and 52 does not change. When the pressing force of the pressure pulse wave sensor 46 is the target pressing force, the brachial artery 16 is occluded by the pressing force of the pressure pulse wave sensor 46. The signal intensity detected by the light receiving elements 68b and 70b of the side light sensor device 52 is substantially zero, but the pressure of the pressure pulse wave sensor 46 is decreased from the target pressure, and the blood flow in the brachial artery 16 is increased. When restarting, the signal intensity detected by the light receiving elements 68b and 70b starts to increase. Further, when the pressing force of the pressure pulse wave sensor 46 is lowered and the pressing force falls below the minimum blood pressure value BP _DIA of the brachial artery 16, the blood flow rates upstream and downstream of the pressure pulse wave sensor 46 become equal. . Therefore, the blood pressure value determining means 134 determines the judgment reference value TH set in advance to a value close to zero from the state in which the signal intensity detected by the light receiving elements 68b and 70b of the downstream optical sensor device 52 is almost zero. _Is determined as the maximum blood pressure value BP _SYS and is detected by the light receiving elements 68a and 70a of the upstream side optical sensor device 50. It is determined when the signal intensity is substantially equal to the signal intensity detected by the light receiving elements 68b and 70b of the downstream side optical sensor device 52, and the pressing force detected by the pressure sensor 110 at that time is set to the minimum blood pressure value BP _DIA . decide.

The optimum pressing force control means 136 calculates the mean blood pressure value BP _MEAN based on the maximum blood pressure value BP _SYS and the minimum blood pressure value BP _DIA determined by the blood pressure value determination means 134, and detects the pressure pulse wave from the brachial artery 16 Therefore, the pressing force of the pressure pulse wave sensor 46 is maintained at the average blood pressure value BP _MEAN . The mean blood pressure value _{BP MEAN} is the diastolic blood pressure value _{BP DIA,} calculated by adding 1/3 of the difference between the systolic blood pressure value _{BP SYS} and diastolic blood pressure _{BP DIA} (i.e. pulse pressure PP). When the pressing force of the pressure pulse wave sensor 46 is maintained at the average blood pressure value BP _MEAN , the pressure pulse wave sensor 46 side of the blood vessel wall of the brachial artery 16 becomes substantially flat, so that it is arranged on the pressing surface 72 of the pressure pulse wave sensor 46. The pressure pulse wave (that is, the brachial pulse wave) having an accurate shape is continuously detected by the pressure detection element 74 that is provided.

  The pressure pulse wave display control means 138 is a pressure pulse wave (that is, detected by the pressure detecting element 74 in a state where the pressing force of the pressure pulse wave sensor 46 is controlled to the optimum pressing force by the optimum pressing force control means 136 (that is, Upper arm pulse wave) is displayed on the display 106.

  FIG. 10 is a flowchart showing control related to blood pressure determination among the control functions of the electronic control unit 80 shown in FIG. In this flowchart, the wavelength selection unit 126 determines which one of the first wavelength light emitting element 64 and the second wavelength light emitting element 66 emits light, and the main body 34 is moved by the orthogonal direction movement control unit 130 and the rotation direction control unit 132. It is executed after being positioned parallel to and just above the brachial artery 16.

  First, in step S1 (hereinafter, step is omitted), pressure increase control for the pressure pulse wave sensor 46 is started. That is, by controlling the driving of the main control valve driving circuit 96, the pressing force of the pressure pulse wave sensor 46 is increased and the pressing force of the pressure pulse wave sensor 46 is controlled by controlling the optical sensor device pressing force control valve driving circuit 104. The pressure in the optical sensor devices 50 and 52 is maintained by lowering the pressure in the upstream pressure chamber 54 and the downstream pressure chamber 56 in response to the pressure increase.

  In subsequent S2, it is determined whether or not the pressing force of the pressure pulse wave sensor 46 has reached the target pressing force. If this determination is negative, this determination is repeated. While the determination of S2 is repeated, the pressure increase control of the pressure pulse wave sensor 46 is continued. On the other hand, if the determination in S2 is affirmative, in S3, pressure reduction control of the pressure pulse wave sensor 46 is started. That is, by controlling the driving of the main control valve driving circuit 96, the pressing force of the pressure pulse wave sensor 46 is lowered at a predetermined speed, and the optical sensor device pressing force control valve driving circuit 104 is controlled to control the pressure pulse wave. The pressure in the optical sensor devices 50 and 52 is maintained by increasing the pressure in the upstream pressure chamber 54 and the downstream pressure chamber 56 in response to the decrease in the pressing force of the sensor 46.

  In the subsequent S4, the first wavelength light emitting element 64b and the second wavelength light emitting element 66b provided in the downstream side optical sensor device 52 are preliminarily determined to be used for determining blood pressure at a predetermined frequency. Make it emit light. In subsequent S5, signals supplied from the light receiving elements 68b and 70b of the downstream side optical sensor device 52 are read. In subsequent S6, the pressing force of the pressure pulse wave sensor 46 is determined based on the signal from the pressure sensor 110.

In subsequent S7, it is determined whether or not the intensity of the signal read in S5 has become larger than a reference value TH set in advance to a value close to zero. If this determination is negative, the steps S4 and after are repeatedly executed to sequentially determine the light emission of the light emitting element 64b or 66b, the reading of signals from the light receiving elements 68b and 70b, and the pressing force of the pressure pulse wave sensor 46. Execute. On the other hand, if the determination in S7 is affirmative, the pressing force determined in S6 immediately before that is determined as the systolic blood pressure value BP _SYS .

  In the subsequent S9, the first wavelength light emitting element 64b and the second wavelength light emitting element 66b provided in the downstream side optical sensor device 52 are preliminarily determined to be used for blood pressure determination at a predetermined frequency. While emitting light, among the first wavelength light emitting element 64a and the second wavelength light emitting element 66a provided in the upstream side optical sensor device 50, the element determined in advance to be used for blood pressure determination is caused to emit light at a predetermined frequency. . In the subsequent S10, the signals supplied from the light receiving elements 68b and 70b of the downstream photosensor device 52 and the signals supplied from the light receiving elements 68a and 70a of the upstream photosensor device 50 are read. In S <b> 11, the pressing force of the pressure pulse wave sensor 46 is determined based on the signal from the pressure sensor 110.

  In the subsequent S12, it is determined whether or not a signal is read for one beat from the light receiving elements 68 and 70 in S10. When this judgment is denied, the above S9 and subsequent steps are repeatedly executed. On the other hand, if the determination in S12 is affirmative, in S13, the pressing force for one beat determined in S11 is averaged. In the subsequent S14, the lower shape of the upstream pulse wave for one beat detected by repeating S9 to S12 and the downstream pulse wave for one beat are compared, and whether or not both are substantially equal. to decide. The lower part of the upstream pulse wave is, for example, a part having a predetermined ratio or less of the amplitude, and the lower part of the downstream pulse wave is the part detected during the period when the lower part of the upstream pulse wave is detected. To do. Whether or not both are substantially equal is determined based on, for example, whether or not the correlation coefficient is equal to or greater than a predetermined value.

If the determination in S14 is negative, the above S9 and subsequent steps are repeated. On the other hand, if the determination in S14 is affirmative, in the following S15, the pressing force calculated in S13 immediately before is determined as the minimum blood pressure value BP _DIA . In the subsequent S16, the main control valve drive circuit 96 is controlled to rapidly discharge the pressure in the main pressure chamber 31, and then in S17, the maximum blood pressure values BP _SYS and S15 determined in S8 are determined. The displayed minimum blood pressure value BP _DIA is displayed on the display unit 106.

  As described above, according to the present embodiment, the optical sensor devices 50 and 52 receive the pulse waves generated by the light emitted from the light emitting elements 64 and 66 being reflected or scattered in the living tissue. The two light receiving elements 68 and 70 are provided at an equal distance from the light emitting elements 64 and 66 with the light emitting elements 64 and 66 interposed therebetween, so that the intensity of the pulse wave detected by the two light receiving elements 68 and 70 is When the optical sensor devices 50 and 52 are positioned so as to be equal, the light emitting elements 64 and 66 are positioned directly above the brachial artery 16. By performing this positioning operation for each of the two optical sensor devices 50 and 52, the brachial artery 16 in a certain section can be easily detected. Further, since the pressure pulse wave sensor 46 is disposed between the two optical sensor devices 50 and 52, the brachial artery 16 can be surely pressed.

  Further, according to the present embodiment, the first wavelength light emitting element 64 that emits a first wavelength of 530 nm to 570 nm and the second wavelength light emitting element 66 that emits red light or near infrared light are provided, When the first wavelength light-emitting element 64 that emits light having a wavelength of 530 nm to 570 nm is positioned in the vicinity of just above the brachial artery 16, the pulse wave represented by the secondary light reflected or scattered in the living tissue. Is inverted with respect to a pulse wave generated by reflection or scattering of red light or near-infrared light in the living tissue, but when the first wavelength light emitting element 64 is not near the brachial artery 16, Since the pulse wave represented by the secondary light is not inverted with respect to the pulse wave represented by the secondary light of red light or near-infrared light, the pulse wave represented by the secondary light of the light emitted from the first wavelength light emitting element 64. Is inverted with respect to the pulse wave represented by the secondary light of red light or near infrared light. By positioning such as first-wavelength light emitting element 64 is located above the artery can be roughly adjusted position of the blood pressure measuring device 10.

  Further, according to the present embodiment, the light is detected by the pair of light receiving elements 64 and 66 respectively provided in the two photosensor devices 50 and 52 by the parallel movement by the orthogonal direction moving device 131 and the rotational movement by the rotating device 42. The main body 34 can be automatically moved so that the pulse wave intensities are the same and the respective intensities are maximized.

Further, according to the present embodiment, the pressing force of the pressure pulse wave sensor 46 is detected by the light receiving elements 68b and 70b provided in the downstream side optical sensor device 52 in the process of being lowered from the target pressing force. The pressing force of the pressure pulse wave sensor 46 when the signal intensity exceeds a predetermined determination reference value TH is determined as the maximum blood pressure value BP _SYS . Further, the pressing force of the pressure pulse wave sensor 46 is further reduced, and the upstream side optical sensor device 50 is provided with the signal intensity detected by the light receiving elements 68b and 70b provided in the downstream side optical sensor device 52. Since the pressing force of the pressure pulse wave sensor 46 when it becomes substantially equal to the signal intensity detected by the light receiving elements 68a and 70a is determined to be the minimum blood pressure value BP _DIA , the blood pressure measuring device can be configured with a simple structure. it can.

In addition, according to the present embodiment, the optimum pressing force is determined based on at least one of the actually measured systolic blood pressure value BP _SYS and the diastolic blood pressure value BP _DIA , and the pressure pulse wave sensor 46 is determined by the optimum pressing force. Since the pressure pulse wave is detected by the pressure detecting element 74 provided on the pressing surface 72 of the pressure pulse wave sensor 46 in a state of pressing the skin, the pressure pulse wave having an accurate shape is continuously generated with a simple structure. Can be detected.

  Next, a second embodiment of the present invention will be described. In the following description, parts common to those in the first embodiment described above are denoted by the same reference numerals and description thereof is omitted. The second embodiment differs from the first embodiment in the number and arrangement positions of elements provided in the upstream photosensor device 150 and the downstream photosensor device 152, and the control function of the electronic control device 80 is the first. The configuration is the same as that of the first embodiment except that the second embodiment is different.

  FIG. 11 is a bottom view of the probe 154 provided in the blood pressure measurement device of the second embodiment, and corresponds to FIG. 3 of the first embodiment. As shown in FIG. 11, the main body 156 of the probe 154 is arranged on both sides of the pressure pulse wave sensor 46 so as to sandwich the pressure pulse wave sensor 46 that also functions as a pressing member, and the pressure pulse wave sensor 46. The upstream photosensor device 150 and the downstream photosensor device 152 are fixed to a substrate 44 not shown in FIG.

  Similar to the first embodiment, the first wavelength light emitting element 64 that emits light having a wavelength of about 530 to 570 nm and red or near infrared light are applied to the pressing surface 150a of the upstream side optical sensor device 150. The second wavelength light emitting element 66 for emitting light is provided, but unlike the first embodiment, a plurality of them (10 in each case in FIG. 11) are provided. The plurality of first wavelength light emitting elements 64 and second wavelength light emitting elements 66 are respectively arranged in the arrangement direction of upstream optical sensor device 150, pressure pulse wave sensor 46, and downstream optical sensor device 152 (that is, in the direction of center line C2). Are arranged in a row and at equal intervals in a direction perpendicular to the direction. The second wavelength light emitting element 66 is disposed closer to the pressure pulse wave sensor 46 than the first wavelength light emitting element 64. In the second embodiment, the first wavelength light emitting element 64 is for detecting the brachial artery, and the second wavelength light emitting element 66 is for detecting the volume pulse wave for calculating oxygen saturation and respiratory rate.

  Furthermore, the pressing surface 150a of the upstream side optical sensor device 150 is positioned adjacent to one end of the array of the first wavelength light emitting elements 64 and the second wavelength light emitting elements 66, and is located at the end of the array. A light receiving element 158 is disposed at a position equidistant from the wavelength light emitting element 64 and the second wavelength light emitting element 66.

  Similarly to the pressing surface 150a of the upstream optical sensor device 150, the first wavelength is also arranged on the pressing surface 152a of the downstream optical sensor device 152 in a line perpendicular to the direction of the center line C2 at regular intervals. A plurality of light emitting elements 64 and second wavelength light emitting elements 66 (10 in each case in FIG. 11) are provided, and a position adjacent to one end of the arrangement of the first wavelength light emitting elements 64 and the second wavelength light emitting elements 66 In addition, the light receiving element 158 is arranged at a position equidistant from the first wavelength light emitting element 64 and the second wavelength light emitting element 66 located at the end of the array. Also in the downstream side optical sensor device 152, the second wavelength light emitting element 66 is disposed closer to the pressure pulse wave sensor 46 than the first wavelength light emitting element 64, and the light receiving element 158 is provided in the upstream side optical sensor device 150. It is arranged on the same side as the side where the light receiving element 158 is arranged.

  FIG. 12 is a functional block diagram showing the main part of the control function of the electronic control unit 80 in the second embodiment, and corresponds to FIG. 5 of the first embodiment. 12 is different from FIG. 5 in light emission control means 160, arterial position determination means 162, optimum body position control means 163, blood pressure value determination means 164, and in the second embodiment, wavelength selection means 126, The pulse wave display means 128 is not provided.

  The light emission control means 160 outputs a drive control signal to the LED drive circuit 90, thereby causing the first wavelength light emitting elements 64 arranged in a line on the pressing surface 150a of the upstream side optical sensor device 150 to be arranged at a predetermined light emission interval. Light is emitted sequentially for a predetermined time, and the downstream side optical sensor device 152 also causes the first wavelength light emitting elements 64 arranged in a line on the pressing surface 152a to sequentially emit light for a predetermined time at a predetermined light emission interval. Note that the time for causing each first wavelength light emitting element 64 to emit light is about one beat or more, and the light emitted from the first wavelength light emitting element 64 of the upstream side optical sensor device 150 is biological tissue. The light transmitted through the inside and detected by the light receiving element 158 of the downstream optical sensor device 152, or conversely, the light emitted from the first wavelength light emitting element 64 of the downstream optical sensor device 152 propagates through the living tissue and is upstream. In order to prevent detection by the light receiving element 158 of the side photosensor device 150, a period during which the first wavelength light emitting element 64 emits light in the upstream photosensor device 150 and a first wavelength in the downstream photosensor device 152. The period for causing the light emitting element 64 to emit light is set to be different.

  The arterial position determination unit 162 compares the plurality of pulse waves detected by the light receiving element 158 with each other when the plurality of first wavelength light emitting elements 64 arranged in a line are sequentially emitted by the light emission control unit 160. Then, based on determining pulse waves whose directions are reversed with respect to a large number of pulse waves, the upper arm among the plurality of first wavelength light emitting elements 64 arranged in a line in the upstream side optical sensor device 150 The upper light emitting element M, which is the first wavelength light emitting element 64 located immediately above or near the artery 16, is determined (that is, the brachial artery 16 is located under which of the plurality of first wavelength light emitting elements 64). In addition, for the downstream side optical sensor device 152, the first wavelength light emitting elements positioned just above or near the brachial artery 16 from the plurality of first wavelength light emitting elements 64 arranged in a row 6 Determining a top-emitting element M is.

  Here, the reason why the upper light emitting element M can be determined by determining the pulse wave in which the direction of the pulse wave is reversed with respect to the direction of many other pulse waves will be described as described in the first embodiment. In addition, in the case of light of the first wavelength which is a wavelength of 530 nm to 570 nm, the pulse wave detected by the light receiving element 158 is obtained when the light emitting source (that is, the first wavelength light emitting element 64) is above the brachial artery 16. The direction of the pulse wave detected by the light receiving element 158 is reversed with respect to the base line when the light source is relatively deviated from the upper part of the brachial artery 16. Accordingly, among the plurality of pulse waves detected by the light receiving element 158, the direction of the pulse wave having the first wavelength light emitting element 64 positioned directly above or in the vicinity of the brachial artery 16 as the light source is true of the brachial artery 16. It reverses with respect to the pulse wave which makes the remaining many 1st wavelength light emitting elements 64 which are not located in upper vicinity the light source. Therefore, the first wavelength light emitting element 64 that is a pulse wave light source whose direction is reversed with respect to many other pulse waves can be determined as the upper light emitting element M. Further, considering the optical path length at which the light emitted from each first wavelength light emitting element 64 is reflected or scattered by the brachial artery 16 and reaches the light receiving element 158, the first light positioned directly above the brachial artery 16 is used. Since the optical path length of the light emitted from the one-wavelength light-emitting element 64 is the shortest, the signal based on the light emission of the first-wavelength light-emitting element 64 located directly above the brachial artery 16 is maximized. Therefore, the first light-emitting element 64 having the largest pulse wave detected by the light-receiving element 158 can be determined as the upper light-emitting element M. The determination of whether or not the pulse wave is the largest is, for example, the average value of the signal intensity detected by the light receiving element 158 while each of the first light emitting elements 64 is emitting light, the maximum value therebetween, and the maximum value therebetween. This is done by comparing the difference between the value and the minimum value.

  Further, the arterial position determining means 162 displays the determined upper light emitting element M in the upstream photosensor device 150 and upper light emitting element M in the downstream photosensor device 152 so that the positions in the arrangement of the upper light emitting elements M can be known. Displayed on the device 106. For example, a schematic diagram of the bottom surface of the main body 156 as shown in FIG. 13 is displayed, and the upper light emitting element M is displayed in a color different from other elements. Alternatively, when the serial number is assigned to each first wavelength light emitting element 64, the number of the upper light emitting element M may be displayed on the display unit 106.

  The optimum body position control means 163 outputs control signals to the rotation control means 132 and the orthogonal direction movement control means 130, and the upper light emitting element M and the downstream of the upstream photosensor device 150 determined by the arterial position determination means 162. The mounting position of the main body 156 is roughly adjusted to the position where the upper light emitting element M of the side light sensor device 152 becomes the first wavelength light emitting element 64 at the center of the array, and then the upper light emitting element M is caused to emit light. The mounting position of the main body 156 is finely adjusted so that the signal intensity detected by the light receiving element 158 is maximized when As described above, when the position of the main body 156 is set to the optimum position, the pressure detection element 74 provided on the pressing surface 72 of the pressure pulse wave sensor 46 is positioned immediately above the brachial artery 16.

The blood pressure value determining unit 164 determines the maximum blood pressure value BP _SYS and the minimum blood pressure value BP _{DIA according} to the control content substantially the same as that of the blood pressure value determining unit 134 of the first embodiment. That is, the blood pressure value determining means 164 of the second embodiment also determines the blood pressure value BP according to the flowchart of FIG. 10 specifically showing the control contents of the blood pressure value determining means 134 of the first embodiment. In the second embodiment, the first wavelength light emitting element 64 and the second wavelength light emitting element 66 are only provided in the upstream photosensor device 150 and the downstream photosensor device 152, respectively. In the example, since the upstream side optical sensor device 150 and the downstream side optical sensor device 152 are provided with a plurality of first wavelength light emitting elements 64 and second wavelength light emitting elements 66, the number of light emitting elements 64 and 66 is different. There is a difference in control contents. That is, in the step corresponding to S4 in FIG. 10, the blood pressure value determining unit 164 is determined in advance among the first wavelength light emitting element 64 or the second wavelength light emitting element 66 located at the center of the array in the lower photosensor device 152. In the step corresponding to S9 in FIG. 10, one of the first wavelength light emitting elements 64 or the second wavelength light emitting elements 66 located in the center of the array in the upper photosensor device 150 is determined in advance. Each of the light emitting elements and the element that emits light in S4 emits light at a predetermined frequency.

  According to the second embodiment described above, the two light sensor devices 150 and 152 each have the first wavelength light emitting elements 64 arranged in a line and the light emitted from the first wavelength light emitting elements 64. Is provided with a light receiving element 158 that receives light generated by reflection or scattering in the living tissue, so that the main body 156 is placed on the skin so that the arrangement direction of the first wavelength light emitting elements 64 intersects the brachial artery 16. When the plurality of pulse waves detected by the light receiving element 158 when the first wavelength light emitting elements 64 arranged in a row are sequentially emitted by the light emission control means 160 are compared, Since the pulse wave from the first wavelength light emitting element 64 located immediately above or near the pulse wave is inverted with respect to the pulse waves from a number of first wavelength light emitting elements 64 that are distant from the upper part of the brachial artery 16, Based on the comparison of the plurality of pulse waves detected by the light receiving element 158 by the position determination unit 162, the position of the brachial artery 16 under the upstream photosensor device 150 and the approximate position of the brachial artery 16 under the downstream photosensor device 152 are approximated. Can be determined. The approximate position of the brachial artery 16 can be determined quickly because it is only necessary to cause the plurality of first wavelength light emitting elements 64 arranged in a row to emit light once. In addition, since the approximate position of the brachial artery 16 can be quickly determined, after the coarse adjustment is performed so that the first wavelength light emitting element 64 at the center of the array becomes the upper light emitting element M, control by the optimum body position control means 163 is performed. The total time until the optimum position of the main body 156 is determined is short. Further, by determining the positions of the two optical sensor devices 150 and 152 to be appropriate positions, the pressure pulse wave sensor 46 disposed between the two optical sensor devices 150 and 152 also reliably moves the brachial artery 16. Can be pressed.

  As mentioned above, although the Example of this invention was described in detail based on drawing, this invention is applied also in another aspect.

  For example, in the first embodiment described above, the light sensor devices 50 and 52 are provided with the two light emitting elements 62 and 64 that emit different wavelengths, but the number of the light emitting elements may be one.

  In the second embodiment described above, the position of the brachial artery 16 is determined by the first wavelength light emitting element 64. However, the position of the brachial artery 16 may be determined by using the second wavelength light emitting element 66. When the brachial artery 16 is located using the second wavelength light emitting element 66, the first wavelength light emitting element 64 is not necessary. Further, when the detection of the volume pulse wave is not necessary, that is, when the oxygen saturation or the respiration rate is not calculated, the second wavelength light emitting element 66 may not be provided.

  In the second embodiment described above, the light receiving element 158 is disposed at a position adjacent to one end of the array of the first wavelength light emitting elements 64. However, the light receiving element 158 is positioned at each light emitting element 64, Any position on the pressing surfaces 150a and 152a may be used as long as light passing through the brachial artery 16 can be detected from 66, for example, a side farther from the pressure pulse wave sensor 46 than the arrangement of the first wavelength light emitting elements 64. It may be.

  In the above-described embodiment, the probe 12 is mounted on the upper arm portion 14, but may be mounted on other parts, for example, an ankle or thigh.

  The above description is only an embodiment, and the present invention can be implemented in variously modified and improved forms based on the knowledge of those skilled in the art.

It is principal part sectional drawing in the state with which the probe with which the blood pressure measuring device to which this invention was applied was equipped with the upper arm part, and is sectional drawing cut | disconnected by the II line | wire shown in FIG. It is principal part sectional drawing in the state with which the probe with which the blood pressure measuring device to which this invention was applied was mounted | worn with the upper arm part, and is sectional drawing cut | disconnected by the II-II line | wire shown in FIG. It is a bottom view of a probe. It is a block diagram explaining the whole blood-pressure measuring device structure. It is a functional block diagram which shows the principal part of the control function of the electronic control apparatus of FIG. A light-emitting element that emits light having a wavelength of 530 nm is positioned directly above the brachial artery, and a light-emitting element that emits red light (Red) and a light-emitting element that emits infrared light (IR) are positioned at positions off from just above the brachial artery. It is a waveform which shows the backscattered light detected by a light receiving element when it is made to do. A light emitting element that emits light having a wavelength of 530 nm is positioned at a position off the upper arm artery, and a light emitting element that emits red light (Red) and a light emitting element that emits infrared light (IR) are positioned directly above the brachial artery. It is a waveform which shows the backscattered light detected by a light receiving element when it is made to do. A light-emitting element that emits light having a wavelength of 530 nm is positioned directly above the brachial artery, and a light-emitting element that emits red light (Red) and a light-emitting element that emits infrared light (IR) are positioned at positions off from just above the brachial artery. It is a waveform which shows the backscattered light detected by a light receiving element when it is made to do. When the light-emitting element that emits light with a wavelength of 530 nm, the light-emitting element that emits red light (Red), and the light-emitting element that emits infrared light (IR) are all located at positions off the upper arm artery, It is a waveform which shows the backscattered light detected by a light receiving element. It is a flowchart which shows the control regarding blood-pressure determination among the control functions of the electronic control apparatus shown in FIG. It is a bottom view of the probe with which the blood pressure measuring device of the 2nd example is equipped, and is a figure corresponding to Drawing 3 of the 1st example. It is a functional block diagram which shows the principal part of the control function of the electronic control apparatus in 2nd Example, and is a figure corresponding to FIG. 5 of 1st Example. It is the schematic of the bottom face of the main body displayed on a display in order to show the position of the brachial artery under the optical sensor device by the arterial position determining means of FIG.

Explanation of symbols

10: Blood pressure measurement device (arterial blood vessel detection device, pressure pulse wave detection device)
34: Main body 42: Rotating device 46: Pressure pulse wave sensor (pressing member)
50: upstream side optical sensor device 52: downstream side optical sensor device 64: first wavelength light emitting element 66: second wavelength light emitting element 68: first light receiving element 70: second light receiving element 74: pressure detecting element 131: orthogonal movement Device 134: Blood pressure value determining means (maximum blood pressure value determining means, minimum blood pressure value determining means)
136: Optimal pressing force control means 150: Upstream optical sensor device 152: Downstream optical sensor device 156: Main body 158: Light receiving element 160: Light emission control means 162: Arterial position determination means 163: Optimal main body position control means

Claims (10)

Having a body mounted on the skin of a living body, the body comprising:
In order to receive light emitted from a light emitting element that emits light of a predetermined wavelength from above the skin toward the artery in the living body, and light generated by the light emitted from the light emitting element being reflected or scattered in the living tissue, Two light sensor devices each including two light receiving elements disposed at an equal distance from the light emitting element with the light emitting element interposed therebetween;
An arterial blood vessel detection device comprising: a pressing member that is disposed between the two photosensor devices and presses the skin of the living body variably. The arterial blood vessel detection device according to claim 1,
The light emitting device includes a first wavelength light emitting device that emits light having a central wavelength in a range of 530 nm to 570 nm, and a second wavelength light emitting device that emits red light or near infrared light. Arterial blood vessel detection device. An orthogonal direction moving device that translates the main body in a direction orthogonal to the arrangement direction of the two photosensor devices and the pressing members;
A rotating device that rotates the main body in a plane including the main body, and
With the orthogonal direction moving device and the rotating device, the pulse wave intensities detected by the pair of light receiving elements respectively provided in the two photosensor devices are the same, and the respective intensities are maximized, The arterial blood vessel detection device according to claim 1 or 2, wherein the main body is positioned. Having a body mounted on the skin of a living body,
The main body includes two photosensor devices and a pressing member that is disposed between the two photosensor devices and presses the skin of the living body variably.
In the photosensor device, a plurality of light-emitting elements that irradiate light of a predetermined wavelength from above the skin toward the artery in the living body are aligned in a direction orthogonal to the arrangement direction of the two photosensor devices and the pressing member. And a light-receiving element for receiving light generated by reflection or scattering of light emitted from the light-emitting element in a living tissue. The arterial blood vessel detection device according to claim 4,
A light emission control means for sequentially emitting light from a plurality of light emitting elements arranged in a row in each of the two photosensor devices;
When a plurality of light emitting elements are sequentially caused to emit light by the light emission control means, the directions of the plurality of pulse waves detected by the light receiving element are compared with each other, or the magnitudes of the plurality of pulse waves are compared with each other. Based on the above, the arterial blood vessel detection further comprising: arterial position determining means for determining the position of the artery under one photosensor device and the position of the artery under the other photosensor device, respectively. apparatus. An orthogonal direction moving device that translates the main body in a direction orthogonal to the arrangement direction of the two photosensor devices and the pressing members;
A rotating device for rotating the main body in a plane including the main body;
In the arterial position determining means, the orthogonal direction is determined so that the position of the artery is determined below the light emitting element at the center of the array among the plurality of light emitting elements arrayed in a line in each of the two photosensor devices. After roughly adjusting the position of the main body using a moving device and a rotating device, the position of the main body is finely adjusted so that the signal intensity from the central light emitting element of the array detected by the light receiving element is maximized. Optimal body position control means,
The arterial blood vessel detection device according to claim 5, further comprising: A blood pressure measurement device for measuring a blood pressure value of a living body,
An arterial blood vessel detection device according to any one of claims 1 to 6,
In the process of continuously changing the pressing force of the pressing member of the arterial blood vessel detection device, one of the two photosensor devices is sequentially detected by the light receiving element provided in the photosensor device located on the downstream side of the artery. Maximal blood pressure value determining means for determining the maximum blood pressure value of the living body based on the pressing force of the pressing member when the detected pulse wave intensity is in a predetermined state. Blood pressure measurement device. The blood pressure measurement device according to claim 7,
An optical sensor device in which the maximum blood pressure value determining means is positioned downstream of the artery among the two optical sensor devices in a process in which the pressing force of the pressing member of the arterial blood vessel detection device is continuously changed. Based on the pressing force of the pressing member when the pulse wave intensity sequentially detected by the light receiving element included in the head exceeds a predetermined range with a preset criterion value close to 0 as a boundary, A blood pressure measurement device characterized by determining a maximum blood pressure value. The blood pressure measurement device according to claim 7 or 8,
In the process in which the pressing force of the pressing member of the arterial blood vessel detection device is continuously changed, the pulse waveform detected by the light receiving element provided in one optical sensor device and the light reception provided in the other optical sensor device A minimum blood pressure value determining means for comparing the pulse waveform detected by the element and determining the minimum blood pressure value of the living body based on the pressing force of the pressing member when the lower shapes of the two pulse waveforms are substantially equal Is further included. A pressure pulse wave detection device for detecting a pressure pulse wave from a living body,
The blood pressure measurement device according to claim 9,
A pressure detecting element that is provided on a pressing surface of the pressing member included in the blood pressure measuring device and detects a pressure pulse wave from the living body;
An average blood pressure value is determined based on the maximum blood pressure value and the minimum blood pressure value determined by the blood pressure measuring device, and the pressing force of the pressing member is maintained at the average blood pressure value in order to continuously detect the pressure pulse wave. The pressure pulse wave detecting device further comprising: an optimum pressing force control means.

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