JP3970697B2 - Biological information processing device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates generally to a biological information processing apparatus, and more particularly to a biological information processing apparatus that generates and outputs report data for displaying or printing measurement results of an ankle brachial blood pressure ratio and pulse wave velocity in a predetermined format.
[0002]
[Prior art]
Conventionally, the ankle brachial index (ABI) is an index indicating the degree of lower limb stenosis or occlusion in obstructive arteriosclerosis, and the pulse wave velocity (PWV) is the stiffness of the arterial wall. Each index is widely used for diagnosis of arteriosclerosis.
[0003]
ABI and PWV are each an index that has meaning alone, but when, for example, arteriosclerosis has spread throughout the body, a value in the normal range may be obtained by measuring only ABI, and the value of ABI is normal It has been found that grasping the progress of the entire arteriosclerosis by PWV helps a more accurate diagnosis.
[0004]
For this reason, in order to facilitate such multi-faceted diagnosis, in recent years, measuring devices (hereinafter referred to as ABI / PWV measuring devices) that integrate an ABI measuring device and a PWV measuring device, which have conventionally been separate devices, are on the market. It has become like this.
[0005]
[Problems to be solved by the invention]
However, since such an ABI / PWV measurement device is generally designed to provide information on measurement results for doctors, information output to a report that presents measurement results together with related information is It is not easy for patients without special knowledge and their families to understand.
[0006]
Since arteriosclerosis causes various diseases and is a progressive disease, early detection and early treatment are very important. For this reason, if the size and price of the device are reduced, there is a possibility that ABI and PWV will be periodically measured at each home in the future, such as blood pressure. At that time, it is desirable that patients and families without specialized knowledge can easily and clearly understand what the measurement results mean.
[0007]
In addition, it is considered that it is meaningful for the patient to know what the measurement results mean even when ABI and PWV measurements are taken at an adult disease screening or the like.
[0008]
[Means for Solving the Problems]
The present invention has been made in view of such problems of the prior art, and the purpose of the present invention is to provide a biological information processing apparatus capable of outputting in a format that allows a person without specialized knowledge to understand the meaning of a measurement result. It is to provide.
[0011]
Another aspect of the present invention is to display or print an ankle-brachial blood pressure ratio (ABI) and pulse wave velocity (PWV) measurement value in a predetermined format that outputs a report representing other related information. Is a biological information processing apparatus that outputs the report data of the same, and generates a PWV two-dimensional graph in which PWV measurement values for the same subject and information on the measurement date and time are read, and PWV measurement values are plotted in time series PWV graph generation means, PWV two-dimensional graph as at least part of the report, layout means for laying out the equivalent age two-dimensional graph indicating the correspondence between the PWV value and the equivalent age, and display or printing based on the layout result Report data generator that generates data in a format suitable for And the PWV axis of the equivalent age two-dimensional graph has the same scale as the PWV axis of the PWV two-dimensional graph, and is laid out so that the values of both PWV axes correspond to each other. Lies in the processing unit.
[0012]
Another aspect of the present invention is to display or print an ankle-brachial blood pressure ratio (ABI) and pulse wave velocity (PWV) measurement value in a predetermined format that outputs a report representing other related information. A biometric information processing apparatus that outputs the report data of ABI, the measurement data acquisition means for reading information on the measurement values and measurement date of ABI and PWV for the same subject, and the evaluation comment corresponding to the acquired measurement values of ABI Evaluation comment acquisition means, equivalent age acquisition means for acquiring equivalent age corresponding to the acquired measurement value of PWV, ABI graph generation means for generating an ABI two-dimensional graph in which the measurement values of ABI are plotted in time series, and PWV PWV graph generation means for generating a PWV two-dimensional graph in which measured values are plotted in time series, and at least one of reports The acquired ABI measurement value and evaluation comment, the acquired PWV measurement value and the corresponding age are arranged in correspondence with each other, and the ABI two-dimensional graph and the information on the ABI value are medically An ABI evaluation area indicating an evaluation comment regarding whether it is considered to have an ABI value range and an evaluation comment corresponding to the range is arranged adjacent to each other, and an equivalent age 2 representing a correspondence between the PWV two-dimensional graph and the value of PWV and the equivalent age A layout means for arranging a dimensional graph, and a report data generation means for generating data in a format suitable for display or printing based on the layout result and outputting it as report data, and corresponding to evaluation comments in the ABI evaluation area The range of the ABI value shown as a visual indication of which range corresponds to the ABI two-dimensional graph The PWV axis of the equivalent age two-dimensional graph has the same scale as the PWV axis of the PWV two-dimensional graph, and the values of both PWV axes correspond to each other. It exists in the biological information processing apparatus characterized by this.
[0013]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, the present invention will be described in detail with reference to the drawings.
(Device configuration)
FIG. 1 is a block diagram illustrating a configuration example of an ABI / PWV measurement apparatus as an example of a biological information processing apparatus according to an embodiment of the present invention.
[0014]
The arithmetic control unit 10 controls the operation of the entire ABI / PWV measurement apparatus according to this embodiment. The arithmetic control unit 10 is a general-purpose computer device having, for example, a CPU, ROM, RAM (including non-volatile RAM), and various interfaces (not shown), for example, a large-capacity storage device such as a built-in or external hard disk, an optical disk, or a ROM When the CPU executes the control program stored in, various operations described below are executed and controlled. Of course, not all may be processed by software, and at least a part thereof may be realized by hardware.
[0015]
The arithmetic control unit 10 measures the blood pressure in both arms and both ankles from the pulse wave information obtained from the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202, and R-ABI (right ankle maximum) is obtained from the result. The ratio between the hypertension value and the upper arm representative blood pressure value) and L-ABI (the ratio between the left ankle maximum blood pressure value and the upper arm representative blood pressure value) are obtained.
[0016]
The arithmetic control unit 10 further detects a pulse wave signal supplied from the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 (if necessary, a heart sound signal or an electrocardiogram signal supplied from the heart sound detection unit 203 Various pulse wave propagation velocities are calculated using an electrocardiogram signal supplied from the unit 204 and a carotid artery wave and a hip artery wave supplied from the pulse wave detection unit 205). The required pulse wave velocity is R-PWV (pulse wave velocity between the upper arm and the right ankle), L-PWV (pulse wave velocity between the upper arm and the left ankle), and B-PWV (between the heart and the upper arm). Pulse wave velocity).
[0017]
The upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 are respectively connected to two cuffs connected via the hoses 21h and 22h using a pump, an exhaust valve, or the like (not shown) according to the control of the arithmetic control unit 10. 21R, L, and 22R, L rubber sac (21aR, 21aL, 22aR, 22aL) is pressurized / depressurized (blood-driven). The upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 are also provided with sensors for detecting pulse waves propagating through the hoses 21h and 22h, such as pressure sensors (211R, L and 221R, L). The pulse wave propagating through the rubber sac and the hose is converted into an electric signal and output to the arithmetic control unit 10. Although FIG. 4 shows a configuration in which the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 are provided independently, they may be integrated.
[0018]
The heart sound detection unit 203 supplies the heart sound signal of the subject detected using the heart sound microphone 23 to the arithmetic control unit 10. The heart sound signal is mainly used to determine the start point of the pulse wave in the heart when determining B-PWV.
[0019]
The electrocardiogram signal detection unit 204 acquires an electrocardiogram signal detected by the electrocardiogram electrodes 24 a and 24 b and supplies it to the arithmetic control unit 10. The electrocardiogram signal is acquired as necessary when performing a more comprehensive diagnosis.
[0020]
The pulse wave detection unit 205 supplies the pulse waves detected by the pulse wave sensors 25 a and 25 b such as amorphous sensors, specifically, the carotid artery wave and the hip artery wave to the arithmetic control unit 10. These pulse waves are used when measuring the aortic PWV.
[0021]
If the accuracy of ABI or PWV is not so required, such as in periodic medical examinations, it is not necessary to obtain heart sounds, electrocardiograms, and aortic PWVs. Therefore, the heart sound detection unit 203 and the electrocardiogram signals necessary to acquire these information The detection unit 204, the pulse wave detection unit 205, and various sensors and electrodes connected thereto are unnecessary.
[0022]
The arithmetic control unit 10 also stores a display unit 70 that can display various operation guidance, measurement results, and diagnostic indicators, a recording unit 75 that can record and output measurement results and diagnostic indicators, a measurement result, and diagnostic indicators, for example, A storage unit 80 composed of a hard disk drive, a writable optical disk drive, a nonvolatile semiconductor memory, etc., a voice generation unit 85 capable of outputting voice guidance output and various notification sounds, a keyboard, a mouse, a button, a touch panel, etc. An input / instruction unit 90 that enables input and instruction is connected.
[0023]
In addition to this, a wired and / or wireless communication interface for communicating with other devices, a storage device using removable media, and the like may be provided. Further, the display unit 70 and the recording unit 75 may be separately connectable to the outside. That is, apart from the display unit 70 and the recording unit 75 built in the apparatus main body, an external display device having a larger display area and / or a larger display color, or an external recording device having a larger print area and / or a larger print color. May be connectable. Thereby, the miniaturization of the main body and the diversity of output can be realized at the same time. In this case, a known display interface and printer interface may be provided.
[0024]
(Measurement process: Preparation before measurement)
A procedure and operation when performing measurement using the ABI / PWV measuring apparatus having such a configuration will be described. Here, a case where measurement with the highest accuracy is performed will be described. It is assumed that initial setting processing relating to device operation such as time setting is performed in advance.
[0025]
First, as a preparation stage, a cuff, a sensor, and the like are attached to the subject. Specifically, cuffs 21R and 21L for upper limbs (hereinafter sometimes collectively referred to as cuff 21) are respectively placed on the right and left upper arms of the subject, and cuffs 22R and 22L for lower limbs (hereinafter collectively referred to as cuffs). 22) may be worn on the subject's ankles. The cuffs 21 and 22 can be attached with a hook-and-loop fastener or the like. Further, the electrocardiographic electrodes 24a and 24b are attached to the left and right wrists, for example. A cream or the like is applied to the mounting site as is usually done for good detection. The attachment site of the electrocardiographic electrode can be changed according to the type of guidance to be acquired.
[0026]
Further, the heart sound microphone 23 is attached to a predetermined position of the subject's chest with a tape or the like. Furthermore, pulse sensors 25a and 25b are attached to the carotid artery pulsation part of the neck and the hip pulsation part of the base of the foot, respectively.
As described above, the heart sound microphone 23, the electrocardiographic electrodes 24a and 24b, and the pulse sensors 25a and 25b are not necessarily attached.
[0027]
Next, the personal information of the age, sex, height, and weight of the subject is input using the input / instruction unit 90. Further, the distance between the left edge of the second intercostal sternum (when the part to which the hip artery wave sensor 25b is attached is the right foot base) and the part to which the hip artery wave sensor 25b is attached is measured and input. When the hip arterial wave sensor 25b is attached to the left groin, the distance from the right edge of the second intercostal sternum is measured and input. This completes the preparation before measurement.
[0028]
(Measurement processing: ABI measurement)
When preparation for measurement is completed and, for example, a measurement start instruction is given from the input / instruction unit 90, the arithmetic control unit 10 first starts blood pressure measurement processing for the extremities in order to measure ABI. Although the order can be arbitrarily set, first, for example, the start of pressurization to the left upper arm cuff 21L is instructed to the upper limb blood pressure control unit 201.
[0029]
The upper limb blood-feeding control unit 201 sends air to the left cuff 21L to inflate the rubber sac 21aL. At the same time, a pulse wave propagates as a pressure wave of air from the rubber sac 21aL through the hose 21h and is detected by the pressure sensor 211L, and this pulse wave is converted into an electrical signal (generally, the pressure sensor itself converts the pressure into electrical pressure). Converted into a signal and output), and output to the arithmetic control unit 10 as a pulse wave signal obtained from the cuff 21L.
[0030]
The arithmetic control unit 10 causes air to be sent to the rubber sac 21aL by the upper limb blood-pulsation control unit 201 until the pulse wave is no longer detected by the pressure sensor 211L, that is, until the pulse wave is no longer detected. Stop pressurization. The cuff pressure at this time can be detected by the pressure sensor 211L. Then, the upper limb blood pressure control unit 201 is instructed to gradually decrease the cuff pressure.
[0031]
The upper limb blood pressure control unit 201 adjusts an exhaust valve (not shown) to release air from the rubber sac 21aL, thereby reducing the cuff at a constant rate. In the process of depressurization, the pulse wave begins to be detected again, and then the maximum from the cuff pressure at the point where the pulse wave suddenly increases, the point where the maximum amplitude of the pulse wave is obtained, and the point where the pulse wave rapidly decreases. Find high blood pressure, mean blood pressure, and minimum blood pressure. The cuff pressure can be calculated using the value at the start of decompression, the decompression rate, and the decompression time. Such a blood pressure measurement method is known as an oscillometric method (volume pulse vibration method). When the minimum blood pressure is determined, the cuff is depressurized at once. Such blood pressure measurement processing is sequentially performed on the remaining three cuffs in the same manner, and the blood pressure measurement at the upper limb and the lower limb is totaled.
[0032]
From the obtained blood pressure, the arithmetic control unit 10 obtains R-ABI and L-ABI as follows, for example.
R-ABI = right ankle systolic blood pressure / upper arm representative blood pressure
L-ABI = Left ankle systolic blood pressure / upper arm representative blood pressure
[0033]
Here, the upper arm representative blood pressure value is
｜ Right arm maximum blood pressure−Left arm maximum blood pressure ｜ When ≧ 10 mmHg, the right arm maximum blood pressure and the left arm maximum blood pressure are high values.
| Right arm maximum blood pressure−left arm maximum blood pressure | <10 mmHg, the average value of the right arm maximum blood pressure and the left arm maximum blood pressure is used.
[0034]
Of course, R-ABI = right ankle maximum blood pressure value / right upper arm representative blood pressure value and L-ABI = left ankle maximum blood pressure value / left arm representative blood pressure value may be obtained without using the upper arm representative blood pressure value. The blood pressure measurement result and the calculated ABI are stored in the storage unit 80, respectively.
[0035]
(Measurement processing: PWV measurement)
Next, the process moves to the PWV measurement process. When the carotid artery wave and the hip artery wave are detected using the pulse wave sensors 25 a and 25 b, the arithmetic control unit 10 acquires these pulse waves via the pulse wave detection unit 205 and also via the heart sound detection unit 203. The generation of a heart sound (for example, a II sound) corresponding to the rise of the pulse wave is detected from the heart sound signal acquired in step S1. Each of the pulse wave and the heart sound signal is subjected to appropriate processing such as A / D conversion and stored in the storage unit 80. Then, the PWV is calculated from the left edge of the second intercostal sternum (when the part to which the hip artery wave sensor 25b is attached is the right foot base) and the distance to the part to which the hip artery wave sensor 25b is attached, which are measured and input in advance during measurement preparation Is obtained as follows.
PWV = 1.3 * AF / (t + tc)
here,
AF: Distance between the left margin of the II intercostal sternum and the attachment site of the hip artery sensor 25b
t: Time difference from the rise of the carotid artery wave to the rise of the hip artery wave
tc: Time difference from the rise of heart sound II to the notch of carotid artery
It is.
[0036]
On the other hand, when the pulse wave sensors 25a and 25b are not used, the PWV is measured as follows. The calculation control unit 10 instructs the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 to pressurize the cuff.
[0037]
Upon receiving the instruction, the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 send air to the cuffs 21 and 22 through the hoses 21h and 22h to the limb cuffs, and pressure sensors (211R, L and L The rubber sac 21aR, 21aL, 22aR, 22aL is inflated until 221R, L) detects a predetermined pressure. This pressure can be set arbitrarily, but if the pressure is too high, the propagation of the pulse will be hindered, the feeling of pressure felt by the subject will increase, and if the pressure is too low, it will be difficult to detect the pulse wave. It is preferable to set a low pressure within a range where there is no hindrance to detection.
[0038]
When the cuff pressure increases, the pulse wave propagates as air pressure waves via the cuff rubber bladders 21aR, 21aL, 22aR, 22aL and the hoses 21h, 22h, and is detected by the pressure sensors (211R, L and 221R, L). Is done. The upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202 convert the pulse wave detected by the pressure sensors (211R, L, and 221R, L) into an electrical signal (generally, the pressure sensor itself converts the pressure into electrical pressure). Converted into a signal and output), and output to the arithmetic control unit 10 as a pulse wave signal obtained from each cuff. The arithmetic control unit 10 stores these pulse wave signals in the storage unit 80 after performing appropriate processing such as A / D conversion.
[0039]
On the other hand, the heart sound detection unit 203 supplies a signal (acceleration signal, sound pressure signal, etc. depending on the configuration of the heart sound microphone 23) input from the heart sound microphone 23 to the arithmetic control unit 10. The arithmetic control unit 10 stores the heart sound signal in the storage unit 80 as well as the pulse wave signal.
[0040]
The arithmetic control unit 10 calculates R-PWV from the pulse wave signal in the upper right arm obtained from the upper limb blood pressure control unit 201 and the pulse wave signal in the right ankle obtained from the lower limb blood pressure control unit 202. Ask. Specifically, the cross-correlation between two pulse wave signals is calculated, and the propagation delay (TR) of the characteristic point (preferably the rising point of the pulse wave) and the height of the subject between the upper arm and lower limb cuff attachment sites R-PWV is obtained from the blood vessel length (the difference between the distance from the aortic origin to the right ankle cuff attachment site and the distance from the aorta origin to the right arm cuff attachment site: L3). Similarly, the propagation delay (TL) obtained from the pulse wave signal in the upper right arm obtained from the upper limb blood pressure control unit 201 and the pulse wave signal in the left ankle obtained from the lower limb blood pressure control unit 202 is obtained. ) And the difference between the distance from the aortic origin to the right ankle cuff attachment site and the distance from the aorta origin to the right arm cuff attachment site (L2), L-PWV is obtained.
[0041]
For B-PWV, the aortic origin is determined from the time difference (TB) from the rise of the heart sound II sound detected from the heart sound signal to the upper right arm cuff pulse wave notch point, the height of the subject, and the like. And the length (L1) of the blood vessel from the upper right arm cuff attachment site to the upper right arm cuff attachment site.
[0042]
Specifically, each PWV is obtained as follows.
R-PWV = L3 / TR
L-PWV = L2 / TL
B-PWV = L1 / TB
[0043]
Further, the arithmetic control unit 10 can store the electrocardiographic signals detected using the electrocardiographic electrodes 24 a and 24 b in the storage unit 80, whether or not the pulse wave sensors 25 a and 25 b are used.
When the PWV measurement is completed, the arithmetic control unit 10 releases the cuff by the upper limb blood pressure control unit 201 and the lower limb blood pressure control unit 202, and ends the measurement process.
[0044]
Note that it is preferable to store various measured biological information and calculated values such as ABI and PWV in association with the personal information of the subject and the measurement date and time. For example, it is possible to create a folder or directory for each subject and create a folder or directory for each measurement in the subject's folder or directory each time measurement is performed, and save the acquired waveform information etc. is there.
[0045]
In the present embodiment, since the ABI / PWV measurement apparatus also serves as the biological information processing apparatus, the ABI / PWV measurement process has been described. However, the biological information processing apparatus according to the present invention can perform ABI / PWV measurement processing if it is possible to output a report in the format described below from the above-described information acquired in advance by the ABI / PWV measurement apparatus. A mechanism for this is not necessary. Such a biological information processing apparatus can be realized by installing and executing software for performing the following report output on a computer apparatus commercially available as a personal computer, for example. Also in this case, the report output may be performed on either a display built in or externally attached to the computer apparatus, or a printer connected directly or indirectly.
[0046]
(Report output processing)
Next, report output processing in the above-described ABI / PWV measuring apparatus will be described with reference to the flowchart of FIG. Here, the description will be made assuming that the data is output by the recording unit 75, but it may be output not only to the display unit 70 but also to an external display device or an external output device as described above.
[0047]
The report output process may be performed automatically after the measurement is completed, or a list of subjects that have been measured in the past and stored in the storage unit 80 is displayed on the display unit 70 as a list, for example, and an input / instruction unit is displayed from the list. It is also possible to output the measurement result for the subject selected by 90. Here, it is assumed that a measurement result for a subject selected from a list of subjects who have measured in the past is output.
[0048]
First, the arithmetic control unit 10 reads out the personal information and measurement results of the selected subject from the storage unit 80 (step S101). Then, the read information is laid out in an output format described later (step S103). In this layout process, an evaluation comment corresponding to the measurement value, an equivalent age (described later) acquisition process, an output data read process for the ABI evaluation area 50 and the data equivalent age area 70 (FIG. 2), an ABI time series area 60 And a two-dimensional graph generation process of the PWV time series region 80 (FIG. 2), a drawing process of arrows 52 and 81 (FIG. 2), and the like. The report output format will be described in detail later.
[0049]
When the layout is completed, the output destination, for example, a format that can be output by the recording unit 75 is converted (step S105). This format conversion includes, for example, resolution conversion according to the output destination (72 or 96 dpi for display, 400 to 600 dpi for printing, etc.), color conversion (conversion to monochrome, increase / decrease in the number of colors, etc.) , Reduction / enlargement, expansion to a bitmap, and the like. When the conversion into a format suitable for the output destination is completed, the converted data is output as report data to the output destination (step S107) and displayed or printed.
[0050]
Also, if the data measured by the ABI / PWV measuring device in advance is placed in a state where the biological information processing device can be acquired via a network or a removable storage medium, the biological information processing device without the ABI / PWV measuring function Even when a report is output by the above, it is possible to output by a similar process. That is, the biological information processing apparatus first acquires list information (such as a subject name list) of measurement data and displays it on the display. Then, after a subject is selected via an input device such as a keyboard and a mouse, the same processing as in steps S101 to S105 described above is performed, and the result is output to a preset output destination such as a display or a printer (step). S107). As a result, a similar report is displayed or printed.
[0051]
(Report format)
FIG. 2 is a diagram illustrating an example of a report output by the biological information processing apparatus according to the present embodiment. The report is roughly divided into the following eight areas.
[0052]
・ Personal information area 10
This is an area for outputting the above-mentioned blood vessel length and the like used for measurement date / time, subject ID, name, age, gender, height, weight and PWV measurement.
[0053]
・ Measurement result numerical area 20
This is an area for outputting numerical information such as blood pressure (highest / lowest (average)), pulse pressure, ABI, PWV, and pulse rate of the extremities together with a schematic diagram of the human body and roughly corresponding to the measurement position.
[0054]
-Waveform information area 30
This is an area for outputting an electrocardiogram waveform (ECG), a cardiac sound waveform (PCG), and a pulse wave (right arm, right foot, and left foot). Marks are given to the characteristic points (rising point, notch point) of the pulse wave and the rising point of the second sound in the heart sound waveform. These waveforms correspond to the portions actually used for the calculation of PWV among the waveforms acquired during the measurement of PWV.
[0055]
ABI and PWV detailed area 40
For ABI and PWV, the measurement results are output in a tabular format together with normal range values and rough indices. In the measurement result numerical area 20, only numerical values are output, whereas in this area, the contents of ABI and PWV inspections and normal values and what the inspection results are considered to have are output together. It is easy for those who have no specialized knowledge to understand the test contents, results and evaluation.
[0056]
In the examination result column, an AHA standard, which will be described later, is output to ABI, and an equivalent age, which will also be described later, is output to PWV.
[0057]
In the example of FIG. 2, B-PWV is not output to the ABI / PWV detailed area 40, but is output instead of or in addition to PWV * (a value obtained by correcting PWV to the standard pressure (80 mmHg)). You may make it.
[0058]
ABI evaluation area 50 and ABI time series area 60
In the ABI time series area 60, the measurement results for the same subject are output in time series. In the example of FIG. 2, the graph is a graph with time (measurement date) on the vertical axis and ABI value on the horizontal axis. The top is the latest measurement result, and the lower the value, the older the measurement result. Here, an example is shown in which L-ABI and R-ABI are output at the same time, but what ABI is displayed and how far back in the past (period or number of measurements) is arbitrarily set Is possible. If there is no past measurement result, only the latest measurement result is output to the top row.
[0059]
In the ABI evaluation area 50, an explanation of what the ABI value is considered to have is output. In the example of FIG. 2, ABI evaluation by AHA (American Heart Association) is output. This ABI evaluation is also described in the inspection result column in the ABI / PWV detailed area 40. Here, the evaluation comment output to the ABI evaluation area 50 is output in a format that can visually grasp how the measurement comment output in the ABI time series area 60 is related.
[0060]
In the example of FIG. 2, for example, a range of ABI values 0.0 to 0.5 recognized by AHA as “possibility of multiple occlusions” is ABI in a two-dimensional graph output in the ABI time series region. The bar 51 having a width corresponding to the range of the ABI value 0.0 to 0.5 in the ABI time series region 60 is evaluated so that it can be visually grasped that the range corresponds to the range of 0.0 to 0.5 on the axis. Output adjacent to the comment. The same applies to other ranges. Data for outputting the ABI evaluation area 50 is stored in advance in a ROM (not shown) in the arithmetic control unit 10, a storage unit 80, or an internal / external storage device (a biological information processing apparatus having no ABI / PWV measurement function). ) In advance. Further, in order to output an evaluation comment to the inspection result in the ABI / PWV detailed area 40, the evaluation comment corresponding to the numerical value range of the ABI is also stored in advance.
[0061]
In the example of FIG. 2, how the numerical range corresponding to the evaluation comment in the ABI evaluation area 50 corresponds to the graph in the ABI time series area 60 is indicated by a bar having a width corresponding to the numerical range in the graph. Although it is shown by being output adjacently or superimposed, it may be expressed by other methods such as showing a range using an arrow as long as the correspondence between the two can be visually grasped.
[0062]
Further, in order to make the correspondence between the two more clear, the color that fills the bar 51 indicating the numerical range corresponding to the evaluation comment and the background color of the corresponding ABI value range 61 in the two-dimensional graph output in the ABI time series region 60 Can also be shared. That is, the bar 51 shown in the ABI evaluation area 50 corresponding to the comment is red in the range of the ABI value 0.0 to 0.5 recognized by the AHA as “there may be a plurality of occlusions”. When filled, the background 61 corresponding to the range of the ABI value 0.0 to 0.5 in the graph of the ABI time series area 60 is painted red. The other comments are processed in the same manner using different colors, whereby the correspondence between the comments in the ABI evaluation area 50 and the measurement results plotted in the graph in the ABI time series area 60 becomes clearer.
[0063]
In addition, when the distance between the comment and the ABI time series area 60 increases, it can be seen how both ends (threshold values) of the bars that visually indicate the numerical range corresponding to the evaluation comment correspond to the ABI value in the ABI time series area. May be difficult. In such a case, for example, by adding a vertical line from the right end (lower threshold) of the bar indicating the numerical range corresponding to the evaluation comment “suspected stenosis or occlusion” in FIG. 2 toward the ABI time series region, The correspondence with the ABI time series area can be grasped more clearly.
[0064]
Further, in FIG. 2, from the vicinity of the plot point of the latest measurement result output to the ABI time series region 60, the ABI evaluation region 50 can be grasped instantaneously to what kind of evaluation the latest measurement result corresponds. An arrow 52 extending inward is output. In the example of FIG. 2, it can be clearly understood that the latest measurement result is included in the normal region according to the AHA standard.
[0065]
When the difference between R-ABI and L-ABI is small, only one arrow 52 may be output as shown in FIG. 2, but when the difference between R-ABI and L-ABI cannot be ignored, When both values cross the threshold value at which the evaluation comment changes, it is also possible to output an arrow from each measurement result.
[0066]
Equivalent age area 70 and PWV time series area 80
In the PWV time-series area 80, the PWV measurement results for the same subject are time-sequentially output in the same manner as the ABI time-series area 60 described above. In the example of FIG. 2, the time is plotted on the vertical axis (measurement date) and the PWV value is plotted on the horizontal axis. The top is the latest measurement result, and the lower the value, the older the measurement result. Here, an example is shown in which L-PWV and R-PWV are output simultaneously, but any PWV is displayed and how far back is output (period or number of measurements) is arbitrarily set. Is possible. If there is no past measurement result, only the latest measurement result is output to the top row.
[0067]
In the equivalent age region 70, an equivalent age graph showing the correlation between the PWV value and the corresponding equivalent age is output. In the equivalent age graph, the horizontal axis represents the graph output to the PWV time series area 80 and the PWV of the scale common scale, and the vertical axis represents the equivalent age. In the three lines output to the equivalent age graph, the two lines on both sides indicate the PWV value range corresponding to the equivalent age, and the center line indicates the average value. The data of the equivalent age area 70 including this graph is stored in advance in the same manner as the data of the ABI evaluation area 50. A graph for each gender may be prepared and selected according to the gender of the subject. In addition, in order to output an evaluation comment as a test result in the ABI / PWV detailed area 40, the equivalent age corresponding to the value of PWV is similarly stored in advance.
[0068]
Further, from the latest measurement result shown in the PWV time series region 80, an arrow 81 that vertically moves to the center line of the equivalent age graph, hits the center line, proceeds to the left at a right angle, and finally reaches the vertical axis of the equivalent age graph. Output. With the arrow 81, it is possible to easily and clearly grasp the equivalent age indicating how many years the latest measurement result corresponds to in terms of blood vessel hardness.
[0069]
The equivalent age corresponding to the latest measurement result is also output to the examination result column in the ABI / PWV detailed area 40 as described above.
[0070]
Thus, according to the ABI / PWV measurement apparatus according to the present embodiment,
(1) In the ABI and PWV detailed area 40, since the current ABI measurement value and the evaluation comment for the value and the current PWV measurement value and the corresponding age for the value are output in association with each other, there is no specialized knowledge. However, it is possible to easily grasp the measured value and its general evaluation.
(2) An ABI evaluation region 50 in which a plurality of ABI ranges and evaluation comments corresponding to this range are described adjacent to the ABI time series region 60 shown in a two-dimensional graph in which ABI measurement values are plotted in time series. In addition, by providing an ABI evaluation area 50 that visually represents the ABI range in correspondence with the ABI range in the two-dimensional graph in the ABI time series area 60, not only can the ABI measurement results be grasped in time series, It is possible to clearly grasp in what areas the measurement results are subject to evaluation (whether they were done) without specialized knowledge.
[0071]
(3) Furthermore, in order to output an equivalent age graph having a common PWV scale adjacent to the PWV time series region 80 shown in a two-dimensional graph in which PWV measurement values are plotted in time series, the hardness of the blood vessel is set as the age. It becomes possible to actually feel, and it becomes easy to recognize how hard one's blood vessels are by comparing one's age with the equivalent age even without specialized knowledge.
(4) In addition, in both the ABI time series area 60 and the PWV time series area 80, the latest measurement is output by outputting arrows 52 and 81 reaching the inside of the ABI evaluation area 50 and the equivalent age area 70 from the latest measurement value. It is possible to easily grasp what kind of evaluation the result receives.
[0072]
[Other Embodiments]
In the above-described embodiment, only the report format in the case of outputting to a vertically long screen or paper has been described, but it is of course possible to output to a horizontally long screen or paper.
[0073]
Further, the positional relationship between the ABI evaluation area 50 and the ABI time series area 60 may be arranged on the left and right instead of the top and bottom. For example, the ABI evaluation area 50 may be arranged on the left and the ABI time series area 60 may be arranged on the right as in the state in which FIG. Is reversed, it is possible to arrange the ABI evaluation area 50 on the right and the ABI time series area 60 on the right. The same is true between the equivalent age region 70 and the PWV time series region 80.
[0074]
Information other than that shown in FIG. 2 can also be included in the report. For example, as shown in FIG. 4A, the pulse wave diagram 21 obtained from each cuff at the time of blood pressure measurement is output near the blood pressure or pulse pressure measured by the same cuff in the measurement result numerical value region 20 ′. Can do. As shown in FIG. 4 (b), the pulse wave diagram is a diagram in which the horizontal axis represents the pressurization value and the vertical axis represents the pulse wave amplitude, and is used to grasp whether the blood pressure measurement was performed correctly. The Such a measurement result numerical area 20 ′ may be output instead of the measurement result numerical area 20 in FIG.
[0075]
In FIG. 2, only the report format having all of the ABI, PWV detailed area 40, ABI evaluation area 50, and equivalent age area 70 has been described. However, if one or more of these are included, the effect of the present invention is can get.
[0076]
【The invention's effect】
As described above, according to the biological information processing apparatus according to the present invention, it is possible to easily understand the meaning of the measurement result even for a subject who has no specialized knowledge or his / her family.
[Brief description of the drawings]
FIG. 1 is a block diagram showing a configuration example of an ABI / PWV measuring apparatus as an example of a biological information processing apparatus of the present invention.
FIG. 2 is a diagram illustrating a report format output by the biological information processing apparatus according to the embodiment of the present invention.
FIG. 3 is a flowchart illustrating report output processing in the biological information processing apparatus according to the embodiment of the present invention.
FIG. 4 is a diagram for explaining a specific example in the case of adding a pulse wave diagram to the report shown in FIG.

Claims (6)

Biological information processing apparatus for outputting report data for displaying or printing a report representing an ankle-brachial blood pressure ratio (ABI) and pulse wave velocity (PWV) measurement value together with other related information Because
A measurement data acquisition means for reading out information related to the measurement value and measurement date and time of PWV for the same subject;
PWV graph generation means for generating a PWV two-dimensional graph in which the measured values of the PWV are plotted in time series;
Layout means for laying out the PWV two-dimensional graph and the equivalent age two-dimensional graph representing the correspondence between the PWV value and the equivalent age as at least a part of the report;
Based on the layout result, it generates data in a format suitable for display or printing, and has report data generation means for outputting as the report data,
The biological information processing apparatus, wherein the PWV axis of the equivalent age two-dimensional graph has a scale equal to the PWV axis of the PWV two-dimensional graph, and the values of both PWV axes correspond to each other. Said layout means, said latest measured values plotted in dimensional graph PWV2 is, the equivalent characterized by further laid an arrow indicating a corresponding age corresponding in age 2 dimensional graph claim 1 biological information processing apparatus according . Biological information processing apparatus for outputting report data for displaying or printing a report representing an ankle-brachial blood pressure ratio (ABI) and pulse wave velocity (PWV) measurement value together with other related information Because
Measurement data acquisition means for reading out information related to measurement values and measurement dates and times of ABI and PWV for the same subject;
An evaluation comment acquisition means for acquiring an evaluation comment corresponding to the acquired measurement value of the ABI;
Equivalent age acquisition means for acquiring equivalent age corresponding to the acquired measurement value of PWV;
ABI graph generating means for generating an ABI two-dimensional graph in which the measured values of the ABI are plotted in time series;
PWV graph generation means for generating a PWV two-dimensional graph in which the measured values of the PWV are plotted in time series;
As the at least part of the report, the acquired ABI measurement value and the evaluation comment, the acquired PWV measurement value and the equivalent age are arranged in correspondence with each other, the ABI two-dimensional graph, and ABI An evaluation comment regarding what kind of information is considered to have a medical value is placed adjacent to the ABI evaluation area indicated by the evaluation comment corresponding to the range of the ABI value, and the PWV two-dimensional graph and the PWV Layout means for arranging an equivalent age two-dimensional graph representing a correspondence between a value and an equivalent age;
Based on the layout result, it generates data in a format suitable for display or printing, and has report data generation means for outputting as the report data,
The range of the ABI value shown corresponding to the evaluation comment in the ABI evaluation area is represented by a figure or combination of figures visually representing which range corresponds to the ABI two-dimensional graph, and the equivalent A biological information processing apparatus characterized in that a PWV axis of an age two-dimensional graph has a scale equal to the PWV axis of the PWV two-dimensional graph, and the values of both PWV axes correspond to each other. 4. The biological information processing apparatus according to claim 3 , wherein the layout unit further lays out an arrow that reaches the inside of the ABI evaluation area from the vicinity of the latest measured value plotted in the ABI two-dimensional graph. Said layout means, said latest measured values plotted in PWV2 dimensional graph, the corresponding arrows indicate corresponding equivalent age in age 2 dimensional graph further characterized by laying claim 3 or claim 4, wherein Biological information processing device. Furthermore, ABI and measurement of PWV, the biological information processing apparatus according to any one of claims 1 to 5, characterized in that it has a measuring means for performing recording.

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