JP3830836B2 - Automatic analyzer - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an automatic analyzer, and more particularly to an automatic analyzer suitable for use in clinical biochemical analysis in which quantitative analysis of blood, urine components and the like is performed by colorimetric analysis.
[0002]
[Prior art]
As a conventional technique relating to automatic analysis used for clinical biochemical analysis, for example, a method called a discrete method is known.
[0003]
FIG. 9 is a block diagram showing the configuration of a conventional automatic analyzer according to the prior art. The automatic analyzer according to the prior art will be described below with reference to FIG. In FIG. 9, 901 is a sample disk, 902 is a reaction disk, 903 is a reagent disk, 904 is a serum sampling mechanism, 905 is a reagent pipetting mechanism, 906 is a washing mechanism, 907 is a multi-wavelength photometer, and 908 is a serum pipettor control. , 910 is a washing water pump, 910 is a reagent pipetter control unit, 911 is a microcomputer, 912 is a printer, 913 is a display device, 914 is an external storage device, 915 is an interface, 916 is an operation panel, and 917 is a thermostatic bath. is there.
[0004]
As shown in FIG. 9, the automatic analyzer according to the prior art includes a sample disk 901 that holds a large number of samples such as serum samples, a reagent disk 903 that holds a plurality of types of reagents, and a reaction disk 902 having a plurality of reaction cells. And is configured. The sample on the sample disk 901 is aspirated and metered by a serum sampling mechanism 904 controlled by a serum pipetter control unit 908, and is discharged into a reaction cell on the reaction disk 902. Is aspirated and metered by the reagent pipetting mechanism 905 controlled by the reagent pipetter control unit 910, and the reagent is placed and discharged into the reaction cell. The liquid mixture in the reaction cell undergoes reaction and develops color while being heated to a constant temperature by a thermostat 917.
[0005]
The colored liquid in the reaction cell is subjected to colorimetric analysis by a multi-wavelength photometer 907 after a certain time or at a certain time interval. This analysis result is sent to the microcomputer 911, converted into the concentration of the target component, etc., displayed on the display device 913 and output to the printer 912, and if necessary, an external storage device 914 such as a flexible disk device. Is remembered.
[0006]
After the measurement, the reaction cell is washed with washing water from the washing water pump 909 by the washing mechanism 906. Further, when the second and third reagents are necessary for the analysis of the sample, these reagents are dispensed into the reaction cell in which the sample is appropriately dispensed by the reagent pipetting mechanism 905.
[0007]
The measurement processing described above can be automatically performed under the control of the microcomputer 911 based on an instruction from the operation panel 916 by the operator.
[0008]
It should be noted that the sample disk 901, reagent disk 903, reaction disk 902, serum sampling mechanism 904, and reagent pipetting mechanism 905 provided in the above-described automatic analyzer according to the prior art may be provided exposed on the upper surface of the housing. In many cases, these are covered with a single open / close lid, or each is covered with an independent lid.
[0009]
Further, in the automatic analyzer according to the prior art, in order to put the reagent into the reagent disk 903, it is necessary to insert the reagent set at a predetermined position by the operator. Furthermore, it is preferable that the amount of reagent used in a day can be normally stored in the reagent disk 903. Therefore, the reagent disk 903 needs to have a large diameter or be provided with a plurality of reagent disks.
[0010]
[Problems to be solved by the invention]
In the above-described automatic analyzer according to the prior art, consideration has been given to automating all processes including the loading of the specimen holding the sample and the loading of the reagent, and interrupting the sample to be analyzed urgently. However, there is a problem that the entire apparatus is not easy to use.
[0011]
The object of the present invention is to solve the above-mentioned problems of the prior art, automate all processes including the introduction of the specimen holding the sample and the introduction of the reagent, and interrupt the sample to be analyzed urgently. It is an object of the present invention to provide an easy-to-use automatic analyzer that can be easily performed.
[0012]
[Means for Solving the Problems]
  The present inventionIn order to achieve the above object, the automatic analyzer according to the present invention has a reaction disk area in which a reaction disk holding a reaction cell is arranged and a reagent disk in which a reagent disk holding a reagent rack is arranged on the upper surface of the automatic analyzer. It is divided into a disk area, and a loading mechanism for loading the reagent rack into the reagent disk is provided above the reagent disk in the reagent disk area, and the reaction disk area has a first open / close lid covering its upper surface opened. A second opening / closing lid that covers the upper surface including the input mechanism is temporarily fixed to the upper surface of the apparatus and attached to the reagent disk area, and a reagent rack input port is provided on the side of the apparatus, A reagent tray is provided that can be opened and closed so as to cover the reagent rack slot.
[0014]
DETAILED DESCRIPTION OF THE INVENTION
Embodiments of an automatic analyzer according to the present invention will be described below in detail with reference to the drawings.
[0015]
FIG. 1 is a perspective view showing the appearance of an automatic analyzer according to an embodiment of the present invention, and FIG. 2 is a diagram for explaining the appearance of the automatic analyzer according to the position embodiment of the present invention and the state of the upper surface of a work shelf. 3 is a perspective view showing a state where the user-side opening / closing lid is opened, FIG. 4 is a top view for explaining the arrangement of the devices on the upper surface of the automatic analyzer, and FIG. 5 is for explaining the arrangement of the devices on the upper surface of the automatic analyzer. It is a perspective view. 1 to 5, 101 is a pedestal section, 102 is a main body casing, 103 is a specimen loading section casing, 104 and 105 are open / close lids, 106, 107 and 206 are transparent windows, and 108 is an interruption specimen loading section. , 109 is a loading groove, 110 is a transparent cover for a specimen loading unit, 111 is a transparent cover for a buffer disk, 112 is an ISE (testing reagent using penetration pressure) exchange space, 113 is an ISE reagent container, 114 is a reagent tray, 115, 116 is a handle, 201 is a reagent rack, 202 is an inclined portion, 203 is a guide groove, 204 is a barcode reading unit, 205 is a reagent rack slot, 301 is a reaction disk, 302 is a reaction cell, 303 is a sample groove, 304, 305, 410, 411 are dispensers, 306, 307, 501, 502 are pipettes, 308 is a cell cleaner, 309, 310 are dispenser columns. 401 is a sample rack loading area, 402 is a sample rack collection area, 403 is a sample rack, 404 is a sample container, 405 is a buffer disk, 406 is a reagent disk, 407 is a dispenser frame, and 408 and 409 are dispenser slide frames. Reference numeral 412 denotes a reagent rack discharge hole, and reference numerals 413 and 414 denote pipette cleaning liquid holders.
[0016]
An automatic analyzer according to an embodiment of the present invention has an appearance as shown in FIG. 1 when the apparatus is not used, and a main body housing 102 and a sample insertion portion housing 103 on a pedestal portion 101. And is configured. The main body housing 102 is provided with a power source, a control mechanism, a thermostatic bath, a washing pump, and the like for driving each device constituting the analyzer, and inside the sample input portion housing 103. Is provided with a transport mechanism for transporting the loaded sample rack, its control mechanism, a power source, etc., but these are not important as the configuration of the present invention and are also provided in the case of the prior art. Since there is, explanation is omitted.
[0017]
As will be described later, various devices for analysis are arranged on the upper surface of the main body housing 102 and are covered with opening / closing lids 104 and 105 when the apparatus is not used. These opening / closing lids 104 and 105 are provided with transparent windows 106 and 107 so that the internal state can be seen. The upper surface of the main body housing 102 at a position covered by the opening / closing lid 104 is provided with a reagent disk, which will be described later, which is not preferable for the user to touch during normal use. For this reason, the opening / closing lid 104 is fixed to the upper surface of the main body housing 102 with screws or the like so that it cannot be opened in normal use, and can be opened only by a service person. That is, the upper surface of the main body housing 102 covered with the opening / closing lid 104 is a serviceman access area. Further, on the upper surface of the main body housing 102 at a position covered by the opening / closing lid 105, a reaction disk or the like in which a reaction cell described later that requires normal maintenance inspection, cleaning, and the like is disposed. The opening / closing lid 105 is provided with a handle 116 on its side surface, and can be opened by lifting the left side of the drawing upward by a hinge or the like provided at a connecting portion on the upper surface of the opening / closing lids 104 and 105. That is, the upper surface of the main body casing 102 covered with the opening / closing lid 105 is a user access area.
[0018]
The opening / closing lid 105 can be opened / closed by a lateral operation, and the lid opening / closing operation can be performed with a small burden. Further, as already described, the opening / closing lid 104 is fixed by a fastener (not shown) such as a screw so that it cannot be easily opened and closed, and it is not desired to be touched by a person who performs analysis work. The reagent disk 406 and the dispensing frame 407 formed on the upper surface thereof are covered.
[0019]
The reagent tray 114 is configured such that when the apparatus is used, the reagent tray 114 can be tilted forward using the handle 115 so that the upper surface thereof is horizontal. Since FIG. 1 shows a state when the apparatus is not used, the reagent tray 114 is closed so as to cover the side surfaces of the open / close lids 104 and 105.
[0020]
The upper surface of the sample input unit housing 103 constitutes a transfer path for transferring the input sample and the processed sample, and a sample input unit transparent cover 110 is provided so as to cover the input sample. ing. The transparent cover 110 for the sample loading part is removed only when the sample is loaded and when the processed sample is removed. Further, on the side surface of the sample loading unit housing 103, an interruption sample loading unit 108 having a loading groove 109 for interrupting and loading a sample to be analyzed urgently protrudes from the side surface of the sample loading unit housing 103. It is provided to do.
[0021]
A part from the upper end of the sample input unit housing 103 is cut out between the main body unit case 102 and the sample input unit case 103 to form an ISE replacement space 112. This space is used. Then, the ISE reagent container 113 in which the test reagent using osmotic pressure is stored can be inserted into or removed from the upper surface of the main body housing 102. Further, as will be described later, it is possible to arbitrarily control the order in which the samples are received from the sample input unit at a position in contact with the sample input unit case 103 on the back side of the main body case 102. The buffer disk which can be set is installed, and the transparent cover 111 for buffer disks is also covered here.
[0022]
As shown in FIG. 2 (a), the automatic analyzer according to the embodiment of the present invention configured with the appearance as described above has a top surface in front of the reagent tray 114 using a handle 115 as shown in FIG. Used to be leveled down. As can be seen from FIG. 2A showing the state where the reagent tray 114 is tilted forward, a transparent window 206 is provided on the side of the opening / closing lid 104 described above from the position where the reagent tray 114 is closed to the bottom. Yes. Further, the corresponding side surface of the opening / closing lid 105 is left open. The reagent tray 114 is attached to a side surface below the upper surface of the main body housing 102 by a hinge or the like so as to be fixed at a position that becomes horizontal when opened. The height from the upper surface of the main body housing 102 to the upper surface of the reagent tray 114 is set to be slightly larger than the height of the reagent rack 201, and the upper surface of the reagent tray 114 from the upper surface of the main body housing 102. A reagent rack inlet 205 is provided on the side surface between the two. For this reason, when the reagent tray 114 is closed, the reagent rack slot 205 is closed.
[0023]
On the upper surface of the reagent tray 114, as shown in FIG. 2 (b), a guide groove 203 provided with an inclined portion 202 in the periphery for inserting the reagent rack 201 into the apparatus is provided in the reagent rack inlet 205 described above. It is provided to connect. Prior to the work, the operator needs to set the reagent, and slides the reagent rack 201 placed on the reagent tray 114 into the guide groove 203 from the inclined portion 202 and then pushes it into the apparatus. Thus, the reagent rack 201 can be set inside. A groove for receiving the reagent rack is provided on the upper surface of the main body housing 102, and a barcode reading unit 204 for reading the barcode recorded on the side surface of the reagent rack 201 is provided on the side of the groove. Yes. The reagent rack 201 inserted in the interior is set at a predetermined position on the reagent disk as will be described later, based on the barcode reading result. The operator can monitor the operation of setting the reagent rack 201 at a predetermined position on the reagent disk from the transparent window 206 described above.
[0024]
The reagent tray 114 can be used as a work table when the reagent rack 201 is inserted, and also has a function as a part of a lid that covers the upper surface of the apparatus together with the open / close lids 104 and 105 when not in use. Yes.
[0025]
In addition, in the conventional automatic analyzer, since the reagent rack must be inserted by the operator into the specified reagent disk insertion position, the accuracy of the operation can be improved. However, according to the embodiment of the present invention, since the loading of the reagent racks into the reagent disk is automated, the reagent racks can be determined without error by simple operations of the operator. It can be set at the insertion position of the reagent disk.
[0026]
For this reason, even if the analysis work is performed without the reagents required for the day being set on the reagent disk, the operator can easily replenish the reagent even if the reagent on the reagent disk runs short on the way. Thus, it is possible to eliminate the necessity of enlarging the reagent disk or providing a plurality of reagent disks, thereby reducing the size of the automatic analyzer.
[0027]
The reagent rack 201 includes three containers inside, and different types of reagents can be stored in these containers. Depending on the type of reagent, the same reagent may be stored in two containers, and when one of the reagents runs out, the entire reagent rack 201 is replaced. Information about the reagent such as the type of reagent stored and the combination thereof is described in the barcode (not shown) described above, and is attached to the side surface of the reagent rack 201.
[0028]
Next, an arrangement state of devices exposed on the upper surface of the main body housing 102 with the opening / closing lid 105 opened upward will be described with reference to FIG.
[0029]
As can be seen from FIG. 3, this state exposes a reaction disk 301 with a number of reaction cells 302 arranged around it, two two dispensers 304, 305, each having pipettes 306, 307, The sample groove 303, the cell cleaner 308, and the ISE reagent container 113. Many reaction cells 302 are injected with a required amount of sample from the sample carried to the sample groove 303 by the dispenser 304, and if necessary, the ISE reagent is dispensed by the dispenser 305. . In the reaction cell 302, one or more other reagents are also dispensed and mixed with the specimen, and heated inside the apparatus to a constant temperature as in the prior art. The mixed solution in the reaction cell 302 thus colored is subjected to colorimetric analysis after a certain time or at certain time intervals by a multi-wavelength photometer.
[0030]
The reaction disk 301 is rotationally controlled by a microcomputer (not shown), and the target reaction cell 302 is positioned at the positions of the pipettes 306 and 307 of the two dispensers 304 and 305 described above. Allows dispensing. The cell cleaner 308 is used to discard and clean the mixed liquid of the specimen and the reagent in the reaction cell 302 that has been processed. The cell cleaner 308 needs to be cleaned after being used for a certain period of time, and the reason that the opening / closing lid 105 is opened as shown in FIG. 3 is for such maintenance.
[0031]
FIG. 3 also shows that a plurality of ISE reagent containers 113 can be set and their shapes. The number and shape of the ISE reagent containers 113 are not important in the present invention. However, each ISE reagent container 113 needs to be set so that the position of the opening provided in the upper part thereof differs depending on the position where the container is set. That is, since the pipette 307 of the dispenser 305 moves in an arc shape centering on the dispenser column 310 that supports the dispenser 305 and sucks the reagent, each ISE reagent container 113 has its The opening is set so as to line up along the position of the arc.
[0032]
Next, the arrangement of devices on the upper surface of the automatic analyzer according to the embodiment of the present invention and the movement of the sample during sample analysis will be described with reference to FIGS. 4 and FIG. 5, the open / close lids 104 and 105 covering the main body housing 102 and the sample loading section housing 103 are removed, and the sample loading section transparent cover 110 and the buffer disk transparent cover 111 are removed. Is also in a state of being removed.
[0033]
A sample rack loading area 401 and a sample rack collection area 402 having a transport function are formed on the upper surface of the sample loading section housing 103, and a plurality of serum samples to be analyzed are stored in the sample rack loading area 401. A sample rack 403 holding the sample container is loaded. The sample rack 403 for which the analysis process has been completed is collected from the sample rack collection area 402. The sample rack 403 can hold a plurality (five in the embodiment of the present invention) of sample containers 404 formed in a test tube, and a label indicating the contents of each sample is attached to control the transport.
[0034]
As described above, the reaction disk 301 having the buffer disk 405 and the multiple reaction cells 302 is arranged on the upper surface of the main body housing 102 on the side of the specimen insertion section housing 103. A dispenser 304 that dispenses a sample into the reaction cell 302 and a dispenser 305 that dispenses an ISE reagent are disposed on the back side and the near side of the reaction disk 301. As can be seen from FIG. 5, the dispensers 304 and 305 are supported by the dispenser support columns 309 and 310 so as to be rotatable and vertically movable. The sample and the ISE reagent can be positioned at the position of the sample and aspirated, and then the sample and the ISE reagent can be discharged into the reaction cell 302 at the position of the reaction cell 302.
[0035]
In addition, a reagent disk 406 is disposed at a position adjacent to the reaction disk 301 on the upper surface of the main body housing 102 on the side far from the sample loading section housing 103. The reagent disk 406 is configured so that the reagent racks 201 can be placed in two rows concentrically, and the reagent rack 201 inserted from the reagent tray 114 is mounted at a predetermined position as will be described in detail later. The The reagent rack 201 having a plurality of reagent containers is transported to the position of the reagent rack discharge hole 412 and discharged when even one reagent in the reagent rack 201 becomes empty.
[0036]
On the upper part of the reagent disk 406, a dispenser frame 407 formed with three arms in an E shape is fixed to the upper surface of the main body housing 102 via legs 503. Dispenser slide arms 408 and 409 having dispensers 410 and 411 are provided between the two arms. These dispenser slide arms 408 and 409 can be controlled to move in the longitudinal direction of the arms constituting the dispenser frame 407, and the dispensers 410 and 411 include the dispenser slide arms 408, 409 can be controlled to move in the longitudinal direction and the vertical direction. As described above, the dispensers 410 and 411 that are controlled to move the predetermined reagent in the predetermined reagent rack 201 to the predetermined reaction cell 302 by the pipettes 501 and 502 held by the pipettes 501 and 502, respectively, based on instructions from the microcomputer or the like. Can be dispensed into.
[0037]
Next, the processing operation from sample introduction to analysis processing sample recovery will be described.
[0038]
A sample is placed in a sample container 404, and a plurality of sleds are held in the sample rack 403 and are loaded into the sample rack loading area 401. At that time, a plurality of sample racks 403 can be loaded. When the analysis process is started, each sample rack 403 is sequentially sent to a buffer disk 405 that can store a plurality of sample racks 403. A sample rack that holds a sample to be examined urgently is loaded from the interrupt sample loading unit 108 and sent to the buffer disk 405 at any time.
[0039]
The buffer disk 405 is controlled and can be rotated in both the clockwise and counterclockwise directions, and the sample rack 201 in the buffer disk 405 is fed into the sample groove 303 serving as a dispensing position. At this time, the rotation of the buffer disk 405 is controlled as described above, so that the sample racks in the buffer disk 405 can be fed into the sample groove 303 in an order different from the order in which the buffer disk 405 was loaded. As a result, even when a sample rack that holds a sample to be examined urgently is loaded, the sample rack can be immediately sent to the sample groove 303 that is the dispensing position.
[0040]
When one of the sample racks 403 is fed into the sample groove 303, the dispenser 304 dispenses the sample in each sample container 404 into the reaction cell 302. At that time, depending on the analysis item, the same specimen is dispensed into a plurality of reaction cells 302. In addition, each time the dispenser 304 dispenses specimens in different specimen containers 404, the pipette is cleaned as is well known. In each of the reaction cells 302 into which the specimen is dispensed, necessary reagents are dispensed by the dispensers 305, 410, and 411 and mixed with the specimen. At the time of dispensing the specimen and reagent, the rotation of the reaction disk 301 is controlled, and the movement of each dispenser 305, 410, 411 is controlled, and the position of the reaction cell 302 and each dispenser are controlled. Are matched so that the positions of the pipettes match.
[0041]
The analysis process of the sample using the mixed solution of the sample and the reagent in the reaction cell 302 is performed in the same manner as described in the prior art, and the reaction mixture 302 is processed by the cell cleaner 308 to have the internal mixed solution. Discarded and washed and ready for the next analytical process.
[0042]
On the other hand, the sample rack 403 after the sample has been dispensed into the reaction cell 302 is returned from the sample groove 303 to the sample rack recovery area 402 on the upper surface of the sample input unit housing 103 via the buffer disk 405. The returned sample rack 403 is stored in a refrigerator or the like until the normality of the analysis result is confirmed, and then discarded.
[0043]
FIG. 6 is a perspective view showing details of the dispensing mechanism, and FIG. 7 is a perspective view showing details of the reagent rack transport mechanism. 6 and 7, 601 is a dispenser drive unit, 701 is a suspension drive unit, 702 is a reagent rack suspension unit, 703 is a suspension claw, and 704 is a claw hanging hole. This is the same as the case of 4.
[0044]
4 and 5, the dispensers 410 and 411 are attached to the dispenser slide frames 408 and 409. In detail, as shown in FIG. 6, the dispensers 410 and 411 are attached to the dispenser slide frames 408 and 409. It is attached to the dispenser driving parts 601 and 602. The dispenser drive units 601 and 602 are controlled to move in the longitudinal direction of the dispenser slide frames 408 and 409 to control the dispensers 410 and 411 to be driven in the vertical direction and to control the suction and discharge of a predetermined amount of reagent. As a result, the pipettes 501 and 502 attached to the dispensers 410 and 411 are inserted into the reagent container, and the reagent is sucked and discharged at the position of the reaction cell 302. The pipettes 501 and 502 are cleaned at the positions of the pipette cleaning liquid holding units 413 and 414 every time the reagent is dispensed.
[0045]
As shown in FIG. 7 (a), the reagent rack transport mechanism is attached to a suspender drive unit 701 provided on the back surface of the dispenser drive unit 602 attached to the dispenser slide frame 409. And a reagent rack suspender 702. As in the case of the dispenser 411, the reagent rack suspender 702 has two arms of the dispenser frame 407 by moving the dispenser slide frame 409 and moving the suspender drive unit 701. It is possible to move to an arbitrary position within the region formed by the above, and it is possible to move up and down by a suspender drive unit 701. As shown in FIG. 7B, the reagent rack suspender 702 is provided with four hanging claws 703 at the lower portion thereof, and the reagent rack 201 corresponds to the four hanging claws 703. A claw hole 704 is provided at the position.
[0046]
Since the reagent rack transport mechanism is configured as described above, when the reagent rack 201 is inserted into the apparatus from the reagent tray 114, the reagent rack transport mechanism can be positioned at the position of the inserted reagent rack 201. . Then, when the reagent rack suspender 702 is driven downward, the four suspension claws 703 provided in the reagent rack suspender 702 are inserted into the nail hanging holes 704 of the reagent rack 201. In this state, when the hanging claws 703 are spread outward, the reagent rack 201 is aligned with the four hanging claws 703 provided in the reagent rack suspension unit 702.
[0047]
After the reagent rack 201 is engaged with the four suspension claws 703, the reagent rack suspension device 702 is driven upward to lift the reagent rack 201 and formed by the two arms of the dispenser frame 407. While moving within the region, the reagent disk 406 is rotated to position the reagent rack 201 at the position of the reagent disk 406 to be set. Then, after the reagent rack suspender 702 is driven downward to place the reagent rack 201 on the reagent disk 406, the reagent rack 201 is set on the reagent disk 406 by releasing the system of the hanging claws 703. be able to. The reagent rack 201 that has run out of reagents inside is transported to the position of the reagent rack discharge hole 412 and discharged, contrary to the above.
[0048]
FIG. 8 is a top view for explaining the arrangement of devices on the top surface of an automatic analyzer according to another embodiment of the present invention. In FIG. 8, 801 is a sample rack conveyance path, 802 is a buffer disk, and 803 is a main body housing.
[0049]
Although the embodiments of the present invention described so far have been described as being configured by one sample insertion unit housing 103 and one main body housing 102 constituting the analysis processing unit, A plurality of main body housings serving as analysis processing units can be coupled to a single sample loading unit housing.
[0050]
Another embodiment of the present invention shown in FIG. 8 is an example in which two main body casings as analysis processing units are coupled to one specimen insertion section casing. The main body housing 102 provided adjacent thereto and the other main body housing 803 connected to the main body housing 102 may be basically configured in the same manner as the main body housing 102 described above. In the embodiment shown in FIG. 8, a sample rack transport path 801 for transporting the sample rack 403 sent out from the buffer disk 405 to the main body housing 803 is provided on the back side of the upper surface of the main body housing 102. In addition, a buffer disk 802 is provided on the upper surface of the main body casing 803 so that the sample rack 403 from the sample rack transport path 801 can be received. The buffer disk 802 may be configured smaller than the buffer disk 405, as can be seen from the figure.
[0051]
In another embodiment of the present invention configured as described above, when the analysis process is started and the sample rack 403 is sent to the buffer disk 405 that can store a plurality of sample racks 403, the sample rack 403 is buffered. The disk 405 distributes the sample rack transport path 801 to the analysis processing unit configured in the main body casing 803 or the sample groove 303 to the analysis processing section configured in the main body casing 102 and sends them out. The sample rack 403 sent to the sample rack transport path 801 is sent to the buffer disk 802 of the main body housing 803 and then sent to the sample groove of the main body housing 803. Then, as described above, the sample stored in the sample rack 403 is analyzed. At this time, a plurality of sample racks 403 may be sent to the buffer disk 802, and the buffer disk 802 can change the order of sending the sample racks 403 to the sample grooves.
[0052]
In the above description, it has been described that two main body casings as analysis processing units are connected to one sample insertion unit casing. However, the present invention provides a main body as an analysis processing unit in one sample insertion unit casing. It is possible to configure a plurality of unit housings coupled together. In that case, a sample rack transport path may be provided in a part other than the main body casing as the last analysis processing part.
[0053]
According to the above-described embodiment of the present invention, it is possible to automate all the processes including the input of the specimen holding the sample and the input of the reagent, and easily interrupt the sample to be analyzed urgently. An easy-to-use automatic analyzer suitable for use in clinical biochemical analysis in which quantitative analysis of blood, urine components and the like is performed by colorimetric analysis can be provided.
[0054]
【The invention's effect】
As described above, according to the present invention, it is possible to automate all processes including the input of the specimen holding the sample and the input of the reagent, and easily interrupt the sample to be analyzed urgently. An easy-to-use automatic analyzer can be provided.
[Brief description of the drawings]
FIG. 1 is a perspective view showing an external appearance of an automatic analyzer according to an embodiment of the present invention.
FIG. 2 is a diagram for explaining the appearance of the automatic analyzer according to the position embodiment of the present invention and the state of the upper surface of the reagent tray.
FIG. 3 is a perspective view showing a state in which a user-side opening / closing lid is opened.
FIG. 4 is a diagram illustrating the arrangement of devices on the upper surface of the automatic analyzer.
FIG. 5 is a perspective view for explaining the arrangement of devices on the upper surface of the automatic analyzer.
FIG. 6 is a perspective view showing details of a dispensing mechanism.
FIG. 7 is a perspective view showing details of a reagent rack transport mechanism.
FIG. 8 is a top view for explaining the arrangement of devices on the top surface of an automatic analyzer according to another embodiment of the present invention.
FIG. 9 is a block diagram showing the configuration of a discrete automatic analyzer according to the prior art.
[Explanation of symbols]
101 pedestal
102, 803 Main unit housing
103 Sample input section housing
104, 105 Open / close lid
106, 107, 206 Transparent window
108 Sample input section for interruption
109 slot
110 Transparent cover for specimen loading part
111 Transparent cover for buffer disk
112 ISE (Inspection reagent using penetration pressure) exchange
113 ISE Reagent Container
114 Reagent tray
115, 116 Handle
201 Reagent rack
202 Inclined part
203 Guide groove
204 Bar code reader
205 Reagent rack slot
301 reaction disk
302 reaction cell
303 Sample groove
304, 305, 410, 411 Dispenser
306, 307, 501, 502 Pipette
308 Cell Cleaner
309, 310 Dispenser post
401 Sample rack loading area
402 Sample rack collection area
403 Sample rack
404 Sample container
405 Buffer disk
406 Reagent disc
407 Dispenser frame
408, 409 Slide frame for dispenser
412 Reagent rack discharge hole
413, 414 Pipette cleaning solution holder
601 and 602 dispenser drive unit
701 Suspension drive unit
702 Reagent rack suspender
703 Hanging nail
704 nail hole
801 Sample rack transport path
802 Buffer disk

Claims (4)

In an automatic analyzer that performs colorimetric analysis of sample components,
The upper surface of the automatic analyzer is divided into a reaction disk area where reaction disks holding reaction cells are arranged and a reagent disk area where reagent disks holding reagent racks are arranged,
A loading mechanism for loading the reagent rack into the reagent disk above the reagent disk in the reagent disk area,
A first opening / closing lid covering the upper surface of the reaction disk area is removably attached,
In the reagent disk area, a second opening / closing lid that covers the upper surface including the charging mechanism is temporarily fixed to the upper surface of the apparatus, and is attached.
An automatic analyzer comprising a reagent tray provided on a side surface of the apparatus, and a reagent tray attached so as to be openable and closable so as to cover the reagent rack inlet . The automatic analyzer according to claim 1, wherein
An automatic analyzer comprising a reagent rack guide groove for guiding the reagent rack to the reagent rack insertion port on an upper surface when the reagent tray is opened . The automatic analyzer according to claim 1 or 2,
2. The automatic analyzer according to claim 1, wherein the reagent disk includes a reagent rack containing a double concentric reagent rack . The automatic analyzer according to any one of claims 1 to 3,
A buffer disk capable of storing a plurality of sample racks for holding a plurality of sample containers;
The automatic analyzer according to claim 1, wherein the buffer disk sends out the sent sample racks in a predetermined order to a sample groove serving as a dispensing position for dispensing the sample in the sample container into the reaction cell .

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