JP3554749B2 - Disinfectant - Google Patents
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- JP3554749B2 JP3554749B2 JP2001046045A JP2001046045A JP3554749B2 JP 3554749 B2 JP3554749 B2 JP 3554749B2 JP 2001046045 A JP2001046045 A JP 2001046045A JP 2001046045 A JP2001046045 A JP 2001046045A JP 3554749 B2 JP3554749 B2 JP 3554749B2
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- hypochlorite
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Description
【０００１】
【発明の属する技術分野】
本発明は、各種器具等を汚染する微生物等を殺菌又は消毒する殺菌消毒剤に関し、詳しくは塩素ガスの発生を防止し、安定かつ高度の殺菌又は消毒作用を有し、医療、食品加工、農水産等の広範な分野に使用される殺菌消毒剤に関する。
【０００２】
【従来の技術及び発明が解決しようとする課題】
従来、次亜塩素酸ナトリウム、次亜塩素酸カルシウム（高度晒し粉）等の次亜塩素酸化合物は、広範な分野で殺菌消毒剤として利用されている。
【０００３】
この次亜塩素酸ナトリウム、次亜塩素酸カルシウム等の次亜塩素酸化合物の水溶液のｐＨと残留塩素濃度の関係については以下のことが知られている。
【０００４】
すなわち、次亜塩素酸化合物水溶液中に含まれる残留塩素は、Ｃｌ2 、ＨＣｌＯ、ＣｌＯ- のいずれかの形で存在する。この水溶液において、ｐＨ７〜８以上の場合には、残留塩素は次亜塩素酸イオン（ＣｌＯ- ）の割合が急激に増加する。この次亜塩素酸イオン（ＣｌＯ- ）は次亜塩素酸（ＨＣｌＯ）に比べて殺菌力が約１／８０である。そのため、ｐＨ７〜８以上の次亜塩素酸化合物水溶液では、次亜塩素酸塩等の塩素剤の投入量を増やさなければ、十分な殺菌効果が期待できない。
【０００５】
他方、次亜塩素酸塩類の水溶液がｐＨ５以下となった場合には、塩素ガス（Ｃｌ2 ）が発生する。塩素ガス（Ｃｌ2 ）の殺菌力については、次亜塩素酸（ＨＣｌＯ）とほぼ同等であるが、塩素ガスは有毒であることから、取り扱いには十分な注意が必要となる。
【０００６】
これらのことから、塩素系殺菌水を生成させる場合には、残留塩素濃度の調整を行うと共に、塩素ガスを発生させずに殺菌力の高いｐＨ域（ｐＨ５〜７）にｐＨ調整を行うことが重要となってくる。
【０００７】
このような残留塩素濃度とｐＨの調整を行って殺菌消毒用の殺菌水を生成する方法としては、電気分解法があるが、一定の装置を必要とするため経済的ではない。
【０００８】
また、次亜塩素酸ナトリウムや次亜塩素酸カルシウム等の塩素剤と酸性剤等を添加する方法が提案されている。酸性剤としては塩酸、リン酸、コハク酸等の酸が通常用いられる。この場合には、次の方法が採られる。すなわち、決められた量の希釈水に塩素剤を混合し、必要な残留塩素濃度に調整する。そして加えた塩素剤の量に比例した酸性剤を加えてｐＨ値の調整を行う。
【０００９】
つまり、塩素剤の投入によって、弱アルカリ性（ｐＨ８〜１０）となった塩素剤水溶液に、酸性剤を加えてｐＨを５〜７とし、これを殺菌水として用いるものである。これらの酸性剤を用いて殺菌水を生成させる際に、製剤の投入手順を誤ってしまった場合には、以下の問題が発生する。
【００１０】
塩素剤より先に酸性剤を投入すると、水溶液のｐＨは５以下の酸性となる。そこへ塩素剤を投入すると塩素ガスが発生し易い状況となる。この塩素ガスによって事故の起こる危険がある。殺菌水を流水で使用する場合、通常の１０〜２００倍程度の濃度で殺菌水を作成し、それを薬液注入装置等によって、水道水に添加、希釈する方法が用いられている。このように高い濃度で使用する場合、製剤の投入手順を誤ってしまうと、酸性剤には緩衝力がないため、よりｐＨが低くなり、塩素ガスが発生し易くなってしまう。
【００１１】
また、通常の方法によって、塩素剤を投入した後、酸性剤を投入したり、両者を同時に投入した場合であっても、水溶液が高濃度の場合には、ｐＨの低下を来たし、塩素ガスが発生する危険性がある。
【００１２】
このような問題を解決する一つの手段として、高度晒し粉と酸性剤粉末とを一定割合で配合した殺菌消毒用製剤が提案されている（特許第３００４９５８号公報）。しかし、この殺菌消毒用製剤は、塩素剤、酸性剤が共に粉末であるため、塩素剤も酸性剤も限られたものしか使用できない。また、このような殺菌消毒用製剤を水溶液とする際の添加量や希釈率を誤った場合や高濃度のものを希釈しつつ使用する場合には、水溶液のｐＨが上記と同様に低くなり、塩素ガス発生の危険性を伴う。
【００１３】
従って、本発明の目的は、塩素ガスの発生を防止し、安定かつ高度の殺菌又は消毒作用を有する殺菌消毒剤を提供することにある。
【００１４】
【課題を解決するための手段】
本発明者は、検討の結果、次亜塩素酸化合物（塩素剤）と特定の有機酸（酸性剤）に加えて該有機酸の塩を含有させることによって、上記目的が達成し得ることを知見した。
【００１５】
本発明は、上記知見に基づきなされたもので、次亜塩素酸ナトリウム又は次亜塩素酸カルシウムと、コハク酸と、該コハク酸の塩とを配合したことを特徴とする殺菌消毒剤を提供するものである。
【００１６】
【発明の実施の形態】
以下、本発明の殺菌消毒剤を詳細に説明する。
【００１７】
本発明の殺菌消毒剤は、上記したように、次亜塩素酸ナトリウム又は次亜塩素酸カルシウム（高度晒し粉）と特定の有機酸と該有機酸の塩とを配合したものである。次亜塩素酸ナトリウム（ＮａＯＣｌ）は、安価でかつ効果に優れることから、殺菌、消毒の目的で広く利用されているものである。また、次亜塩素酸カルシウムは、上下水水、プール等の殺菌剤やパルプ、紙、繊維の漂白剤として汎用されているものである。
【００１８】
本発明では、有機酸として、コハク酸が用いられる。また、有機酸の塩としては、カリウム塩、ナトリウム塩が一般的であるが、カルシウム塩、マグネシウム塩やその他の金属塩も適宜使用可能である。このように、特定の有機酸とその塩とを併せて用いることによって、殺菌水のｐＨ緩衝力が大きくなり、濃度変化に対するｐＨ変化を小さくすることができる。
【００１９】
本発明の殺菌消毒剤は、塩素剤、有機酸の種類によって、好適な配合割合が存在する。このような好適な配合割合の一例を下記に示す。
【００２０】
（次亜塩素酸ナトリウムを用いる場合）
次亜塩素酸ナトリウムの１２％溶液１ｍｌに対して、下記の割合で配合することが望ましい。
コハク酸０．１〜３ｇ、コハク酸塩、好ましくはナトリウム塩として０．１〜１５ｇ
【００２１】
（次亜塩素酸カルシウムを用いる場合）
次亜塩素酸カルシウム１ｇに対して、下記の割合で配合することが好ましい。
コハク酸０．５〜３ｇ、好ましくは２〜２．５ｇ、コハク酸塩０．１〜１５ｇ
【００２２】
有機酸及びその塩の配合割合が、上記範囲未満では水に溶かした際のｐＨが高くなり、水溶液中の次亜塩素酸の存在比が大きくなり、殺菌力が低下する。また、有機酸及びその塩の配合割合が、上記範囲を超えると水に溶かした際のｐＨが低くなり過ぎ、塩素ガスが発生する危険が生じる場合がある。
【００２３】
本発明の殺菌消毒剤の剤型は、粉末剤、錠剤、液剤等のいずれでもよいが、最終的に水に溶解、希釈され、残留塩素濃度２０〜４００ｐｐｍ、ｐＨ５〜７に調整されることにより、安定かつ高度の殺菌又は消毒作用を有する。
【００２４】
【実施例】
以下、実施例に基づき本発明を具体的に説明する。
【００２５】
〔実施例１−１〜１−２及び比較例１−１〜１−２〕
（塩素剤と有機酸を用いた場合と塩素剤と有機酸とその塩を用いた場合との比較）
塩素剤として次亜塩素酸カルシウム（７０％高度晒し粉）、有機酸としてコハク酸、その塩としてナトリウム塩を用い、ｐＨ４〜６、残留塩素濃度７０ｐｐｍ又は３５０ｐｐｍの殺菌水を調製した。なお、通常の操作とは逆に有機酸、有機酸とその塩を先に配合し、塩素剤は後に配合した。
【００２６】
(1) 比較例１−１
ｐＨ７．２８の水道水に、コハク酸０．１４ｇ／ｌを配合した。この時のｐＨは４．３８であった。次いで、次亜塩素酸カルシウム（７０％高度晒し粉）０．１ｇ／ｌを配合した。この時のｐＨは５．５８であった。
【００２７】
(2) 実施例１−１
ｐＨ７．２８の水道水に、コハク酸０．２ｇ／ｌ及びコハク酸ナトリウム０．７ｇ／ｌを配合した。この時のｐＨは５．１８であった。次いで、次亜塩素酸カルシウム（７０％高度晒し粉）０．１ｇ／ｌを配合した。この時のｐＨは５．６３であった。
【００２８】
(3) 比較例１−２
ｐＨ７．２８の水道水に、コハク酸０．７ｇ／ｌを配合した。この時のｐＨは３．４６であった。次いで、次亜塩素酸カルシウム（７０％高度晒し粉）０．５ｇ／ｌを配合した。この時のｐＨは４．８５であった。
【００２９】
(4) 実施例１−２
ｐＨ７．２８の水道水に、コハク酸１ｇ／ｌ及びコハク酸ナトリウム３．５ｇ／ｌを配合した。この時のｐＨは５．０３であった。次いで、次亜塩素酸カルシウム（７０％高度晒し粉）０．５ｇ／ｌを配合した。この時のｐＨは５．３８であった。
【００３０】
〔実施例２−１〜２−２及び比較例２−１〜２−２〕
（塩素剤と有機酸を用いた場合と塩素剤と有機酸とその塩を用いた場合との比較）
塩素剤として次亜塩素酸ナトリウム、有機酸としてコハク酸、その塩としてナトリウム塩を用い、ｐＨ６〜７、残留塩素濃度７０ｐｐｍ及び３５０ｐｐｍの殺菌水を調製した。なお、通常の操作とは逆に有機酸、有機酸とその塩を先に配合し、塩素剤は後に配合した。
【００３１】
(1) 比較例２−１
ｐＨ７．２６の水道水に、コハク酸０．１２ｇ／ｌを配合した。この時のｐＨは４．４６であった。次いで、次亜塩素酸ナトリウム１ｍｌ／ｌを配合した。この時のｐＨは６．０７であった。
【００３２】
(2) 実施例２−１
ｐＨ７．２６の水道水に、コハク酸０．１２ｇ／ｌ及びコハク酸ナトリウム０．３４ｇ／ｌを配合した。この時のｐＨは５．３８であった。次いで、次亜塩素酸ナトリウム１ｍｌ／ｌを配合した。この時のｐＨは６．１５であった。
【００３３】
(3) 比較例２−２
ｐＨ７．２８の水道水に、コハク酸０．６ｇ／ｌを配合した。この時のｐＨ３．５６であった。次いで、次亜塩素酸ナトリウム５ｍｌ／ｌを配合した。この時のｐＨ５．４８であった。
【００３４】
(4) 実施例２−２
ｐＨ７．２８の水道水に、コハク酸０．６ｇ／ｌ及びコハク酸ナトリウム１．７ｇ／ｌを配合した。この時のｐＨ５．０１であった。次いで、次亜塩素酸ナトリウム５ｍｌ／ｌを配合した。この時のｐＨ５．９０であった。
【００４３】
〔実施例３−１〜３−２及び比較例３−１〜３−２〕
（塩素剤と有機酸を用いた場合と塩素剤と有機酸とその塩を用いた場合との比較）
塩素剤として次亜塩素酸カルシウム（７０％高度晒し粉）、有機酸としてコハク酸、その塩としてナトリウム塩を用い、ｐＨ４〜６、残留塩素濃度７０ｐｐｍ又は３５００ｐｐｍの殺菌水を調製した。
【００４４】
(1) 比較例３−１
ｐＨ７．２８の水道水に、次亜塩素酸カルシウム（７０％高度晒し粉）０．１ｇ／ｌ及びコハク酸０．１４ｇ／ｌを配合した。この時のｐＨは５．６６であった。
【００４５】
(2) 実施例３−１
ｐＨ７．２８の水道水に、次亜塩素酸カルシウム（７０％高度晒し粉）０．１ｇ／ｌ、コハク酸０．２ｇ／ｌ及びコハク酸ナトリウム０．６５ｇ／ｌを配合した。この時のｐＨは５．６１であった。
【００４６】
(3) 比較例３−２
ｐＨ７．２８の水道水に、次亜塩素酸カルシウム（７０％高度晒し粉）５ｇ／ｌ及びコハク酸７ｇ／ｌを配合した。この時のｐＨは４．５５であった。
【００４７】
(4) 実施例３−２
ｐＨ７．２８の水道水に、次亜塩素酸カルシウム（７０％高度晒し粉）５ｇ／ｌ、コハク酸１０ｇ／ｌ及びコハク酸ナトリウム３２．５ｇ／ｌを配合した。この時のｐＨは５．１６であった。
【００５８】
〔実験例１〕
実施例１−１で調製した殺菌水９ｍｌ中に、大腸菌菌液１ｍｌを加え、１分間放置後の１ｍｌ中の生菌数を測定した。また、対照として水道水（対照１）及び蒸留水（対照２）を用い、上記と同様の条件で大腸菌菌液を加え、１ｍｌ中の生菌数を測定した。その結果は、次の通りであった。
実施例１−１の殺菌水 不検出
水道水（対照１） ４．２×１０3 個／ｍｌ
蒸留水（対照２） １．５×１０7 個／ｍｌ
【００５９】
上記結果から明らかなように、有機酸とその塩を併用して配合することにより、ｐＨの低下が起こりにくく、殺菌消毒剤（水溶液）の濃度が高くてもこのことは維持される。これに対して、有機酸のみを配合した場合には、ｐＨの低下が起こり易く、殺菌消毒剤（水溶液）の濃度が高い場合にはこの傾向が顕著であり、塩素ガスが発生する危険性が高くなる。
【００６０】
【発明の効果】
本発明の殺菌消毒剤は、塩素ガスの発生を防止し、安定かつ高度の殺菌又は消毒作用を有する。特に高濃度においても、ｐＨの低下が生じにくく、塩素ガスが発生する危険性が極めて低い。従って、本発明の殺菌消毒剤は、広範な用途に使用可能である。[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a germicidal disinfectant for disinfecting or disinfecting microorganisms contaminating various instruments and the like. More specifically, the present invention relates to a medical, food processing, agricultural The present invention relates to a disinfectant used in a wide range of fields such as fisheries.
[0002]
Problems to be solved by the prior art and the invention
Conventionally, hypochlorite compounds such as sodium hypochlorite and calcium hypochlorite (highly bleached powder) have been used as disinfectants in a wide range of fields.
[0003]
It is known that the relationship between the pH of an aqueous solution of a hypochlorite compound such as sodium hypochlorite and calcium hypochlorite and the residual chlorine concentration is as follows.
[0004]
That is, the residual chlorine contained in the aqueous solution of hypochlorite compound exists in any form of Cl 2 , HClO and ClO − . In this aqueous solution, when the pH is 7 to 8 or more, the proportion of residual chlorine in hypochlorite ion (ClO − ) sharply increases. This hypochlorite ion (ClO − ) has a sterilizing power of about 1/80 as compared with hypochlorous acid (HClO). Therefore, in the aqueous solution of hypochlorite compound having a pH of 7 to 8 or more, a sufficient sterilizing effect cannot be expected unless the amount of the chlorine agent such as hypochlorite is increased.
[0005]
On the other hand, when the aqueous solution of hypochlorites has a pH of 5 or less, chlorine gas (Cl 2 ) is generated. The sterilizing power of chlorine gas (Cl 2 ) is almost the same as that of hypochlorous acid (HClO). However, since chlorine gas is toxic, sufficient care must be taken when handling it.
[0006]
From these facts, when generating chlorine-based sterilizing water, it is necessary to adjust the residual chlorine concentration and adjust the pH to a high sterilizing power pH range (pH 5 to 7) without generating chlorine gas. It becomes important.
[0007]
As a method for producing such sterilized water for sterilization by adjusting the residual chlorine concentration and pH, there is an electrolysis method, but it is not economical because a certain device is required.
[0008]
Further, a method has been proposed in which a chlorinating agent such as sodium hypochlorite and calcium hypochlorite and an acidizing agent are added. Acids such as hydrochloric acid, phosphoric acid, and succinic acid are usually used as the acidic agent. In this case, the following method is adopted. That is, a chlorine agent is mixed with a predetermined amount of dilution water to adjust to a required residual chlorine concentration. Then, the pH value is adjusted by adding an acid agent in proportion to the amount of the added chlorine agent.
[0009]
That is, the pH is adjusted to 5 to 7 by adding an acidic agent to a weakly alkaline aqueous solution (pH 8 to 10) of the chlorinating agent aqueous solution by adding the chlorinating agent, and this is used as sterilizing water. When producing sterilized water using these acidic agents, if the procedure for adding the preparation is mistaken, the following problems occur.
[0010]
When the acid agent is added before the chlorine agent, the pH of the aqueous solution becomes acidic to 5 or less. When a chlorine agent is introduced therein, chlorine gas is easily generated. There is a danger of accidents due to this chlorine gas. When using sterilized water in flowing water, a method is used in which sterilized water is prepared at a concentration of about 10 to 200 times the normal concentration, and the sterilized water is added to and diluted with tap water using a chemical injection device or the like. In the case of using such a high concentration, if the injection procedure of the preparation is erroneous, the pH becomes lower and the chlorine gas is easily generated because the acidic agent has no buffering power.
[0011]
Also, according to the usual method, after the chlorine agent is added, the acid agent is added, or even when both are added at the same time, when the aqueous solution has a high concentration, the pH is lowered, and the chlorine gas is removed. There is a risk of occurring.
[0012]
As one means for solving such a problem, there has been proposed a preparation for disinfection and disinfection in which a highly bleached powder and an acidic agent powder are mixed at a fixed ratio (Japanese Patent No. 30000498). However, since both the chlorinating agent and the acidifying agent are powders in this disinfecting preparation, only a limited amount of the chlorinating agent and the acidifying agent can be used. In addition, when the amount or dilution ratio of such a disinfectant preparation when used as an aqueous solution is incorrect or used while diluting a high-concentration one, the pH of the aqueous solution becomes lower as described above, With the danger of generating chlorine gas.
[0013]
Therefore, an object of the present invention is to provide a disinfectant which prevents the generation of chlorine gas and has a stable and high disinfection or disinfecting action.
[0014]
[Means for Solving the Problems]
The present inventors, as a result of the study, found that by incorporating salts of the organic acids in addition to the hypochlorite compound (pesticides) and a specific organic acid (acidic agent), the object can be achieved did.
[0015]
The present invention has been made based on the above findings, provides a sodium hypochlorite or calcium hypochlorite, and co-Haq acid, a disinfectant, characterized in that blended with the salt of the succinic acid Is what you do.
[0016]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, the disinfectant of the present invention will be described in detail.
[0017]
As described above, the disinfectant of the present invention is a mixture of sodium hypochlorite or calcium hypochlorite (highly bleached powder), a specific organic acid, and a salt of the organic acid. Sodium hypochlorite (NaOCl) is widely used for the purpose of sterilization and disinfection because it is inexpensive and has excellent effects. Calcium hypochlorite is commonly used as a bactericide for sewage water, pools, and the like, and a bleaching agent for pulp, paper, and fiber.
[0018]
In the present invention, as the organic acid, it is co-Haq acid used. Also, as the salts of organic acids, potassium salts, sodium salt is generally, calcium salts, also magnesium salts and other metal salts can be appropriately used. As described above, by using a specific organic acid and a salt thereof in combination, the pH buffering power of the sterilizing water is increased, and the pH change with respect to the concentration change can be reduced.
[0019]
The disinfectant of the present invention has a suitable compounding ratio depending on the type of the chlorinating agent and the organic acid. An example of such a suitable mixing ratio is shown below.
[0020]
(When using sodium hypochlorite)
Against 12% solution 1ml of sodium hypochlorite, it is desirable in a proportion below follow.
0.1 to 3 g of succinic acid, 0.1 to 15 g as succinate, preferably sodium salt
[0021]
(When using calcium hypochlorite)
To calcium hypochlorite 1g, it is preferably added at a ratio of under SL.
Succinic acid 0.5 to 3 g, preferably 2 to 2.5 g, succinate 0.1 to 15 g
[0022]
When the compounding ratio of the organic acid and its salt is less than the above range, the pH when dissolved in water increases, the abundance ratio of hypochlorous acid in the aqueous solution increases, and the sterilizing power decreases. On the other hand, when the mixing ratio of the organic acid and its salt exceeds the above range, the pH when dissolved in water becomes too low, and there is a possibility that chlorine gas is generated.
[0023]
The dosage form of the germicidal disinfectant of the present invention may be any of powders, tablets, liquids, etc., but is finally dissolved and diluted in water, and is adjusted to a residual chlorine concentration of 20 to 400 ppm and a pH of 5 to 7 by It has a stable and high sterilizing or disinfecting action.
[0024]
【Example】
Hereinafter, the present invention will be specifically described based on examples.
[0025]
[Examples 1-1 to 1-2 and Comparative Examples 1-1 to 1-2]
(Comparison between using chlorine agent and organic acid and using chlorine agent, organic acid and its salt)
Sterilized water having a pH of 4 to 6 and a residual chlorine concentration of 70 ppm or 350 ppm was prepared using calcium hypochlorite (70% highly bleached powder) as a chlorine agent, succinic acid as an organic acid, and a sodium salt as a salt thereof. In addition, contrary to a normal operation, an organic acid, an organic acid and a salt thereof were first added, and a chlorine agent was added later.
[0026]
(1) Comparative Example 1-1
0.14 g / l of succinic acid was mixed with tap water of pH 7.28. The pH at this time was 4.38. Next, 0.1 g / l of calcium hypochlorite (70% highly bleached powder) was blended. The pH at this time was 5.58.
[0027]
(2) Example 1-1
0.2 g / l of succinic acid and 0.7 g / l of sodium succinate were mixed into tap water having a pH of 7.28. At this time, the pH was 5.18. Next, 0.1 g / l of calcium hypochlorite (70% highly bleached powder) was blended. The pH at this time was 5.63.
[0028]
(3) Comparative Example 1-2
0.7 g / l of succinic acid was mixed with tap water of pH 7.28. The pH at this time was 3.46. Subsequently, 0.5 g / l of calcium hypochlorite (70% highly bleached powder) was blended. The pH at this time was 4.85.
[0029]
(4) Example 1-2
1 g / l of succinic acid and 3.5 g / l of sodium succinate were mixed with tap water of pH 7.28. The pH at this time was 5.03. Subsequently, 0.5 g / l of calcium hypochlorite (70% highly bleached powder) was blended. The pH at this time was 5.38.
[0030]
[Examples 2-1 to 2-2 and Comparative Examples 2-1 to 2-2]
(Comparison between using chlorine agent and organic acid and using chlorine agent, organic acid and its salt)
Using sodium hypochlorite as a chlorine agent, succinic acid as an organic acid, and a sodium salt as its salt, sterilized water having a pH of 6 to 7, a residual chlorine concentration of 70 ppm, and 350 ppm was prepared. In addition, contrary to a normal operation, an organic acid, an organic acid and a salt thereof were first added, and a chlorine agent was added later.
[0031]
(1) Comparative Example 2-1
0.12 g / l of succinic acid was mixed with tap water of pH 7.26. The pH at this time was 4.46. Next, 1 ml / l of sodium hypochlorite was blended. At this time, the pH was 6.07.
[0032]
(2) Example 2-1
0.12 g / l of succinic acid and 0.34 g / l of sodium succinate were mixed with tap water having a pH of 7.26. The pH at this time was 5.38. Next, 1 ml / l of sodium hypochlorite was blended. The pH at this time was 6.15.
[0033]
(3) Comparative Example 2-2
0.6 g / l of succinic acid was mixed with tap water of pH 7.28. At this time, the pH was 3.56. Next, 5 ml / l of sodium hypochlorite was blended. The pH at this time was 5.48.
[0034]
(4) Example 2-2
0.6 g / l of succinic acid and 1.7 g / l of sodium succinate were mixed with tap water having a pH of 7.28. The pH at this time was 5.01. Next, 5 ml / l of sodium hypochlorite was blended. The pH at this time was 5.90.
[0043]
EXAMPLE 3 -1 3 -2 and Comparative Example 3 -1 3 -2]
(Comparison between using chlorine agent and organic acid and using chlorine agent, organic acid and its salt)
Sterilized water having a pH of 4 to 6 and a residual chlorine concentration of 70 ppm or 3500 ppm was prepared using calcium hypochlorite (70% highly bleached powder) as a chlorine agent, succinic acid as an organic acid, and a sodium salt as a salt thereof.
[0044]
(1) Comparative Example 3 -1
0.1 g / l of calcium hypochlorite (70% highly bleached powder) and 0.14 g / l of succinic acid were mixed with tap water of pH 7.28. The pH at this time was 5.66.
[0045]
(2) Example 3-1
0.1 g / l of calcium hypochlorite (70% highly bleached powder), 0.2 g / l of succinic acid and 0.65 g / l of sodium succinate were mixed with tap water of pH 7.28. The pH at this time was 5.61.
[0046]
(3) Comparative Example 3-2
5 g / l of calcium hypochlorite (70% highly bleached powder) and 7 g / l of succinic acid were mixed in tap water of pH 7.28. At this time, the pH was 4.55.
[0047]
(4) Example 3-2
5 g / l of calcium hypochlorite (70% highly bleached powder), 10 g / l of succinic acid and 32.5 g / l of sodium succinate were mixed with tap water of pH 7.28. At this time, the pH was 5.16.
[0058]
[Experimental example 1]
1 ml of Escherichia coli bacteria solution was added to 9 ml of the sterilized water prepared in Example 1-1, and the number of viable cells in 1 ml after standing for 1 minute was measured. In addition, tap water (control 1) and distilled water (control 2) were used as controls, E. coli bacteria solution was added under the same conditions as above, and the number of viable bacteria in 1 ml was measured. The results were as follows.
Sterilized water of Example 1-1 non-detected tap water (control 1) 4.2 × 10 3 cells / ml
Distilled water (control 2) 1.5 × 10 7 / ml
[0059]
As is evident from the above results, by combining the organic acid and its salt in combination, the pH is unlikely to decrease, and this is maintained even when the concentration of the disinfectant (aqueous solution) is high. On the other hand, when only an organic acid is blended, the pH tends to decrease, and when the concentration of the disinfectant (aqueous solution) is high, this tendency is remarkable, and there is a danger of generating chlorine gas. Get higher.
[0060]
【The invention's effect】
The disinfectant of the present invention prevents the generation of chlorine gas and has a stable and high disinfection or disinfecting action. In particular, even at a high concentration, the pH hardly decreases, and the danger of generating chlorine gas is extremely low. Therefore, the germicidal disinfectant of the present invention can be used for a wide range of applications.
Claims (4)
コハク酸０．１〜３ｇ、コハク酸塩０．１〜１５ｇAgainst 12% solution 1ml of sodium the hypochlorite, disinfectant according to claim 1, wherein the succinic acid and its salt is blended in an amount below follow.
0.1-3 g of succinic acid, 0.1-15 g of succinate
コハク酸０．５〜３ｇ、コハク酸塩０．１〜１５ｇWith respect to the calcium hypochlorite 1g, disinfectant according to claim 1, wherein the succinic acid and its salt is blended in an amount below follow.
Succinic acid 0.5-3g, succinate 0.1-15g
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| JP2001046045A JP3554749B2 (en) | 2001-02-22 | 2001-02-22 | Disinfectant |
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| WO2007061236A1 (en) * | 2005-11-23 | 2007-05-31 | Republic Of Korea(Management : Rural Development Administration) | Cleaner for precaution against of cow's hoof, manufacturing method thereof, and using method thereof |
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| JP2018035123A (en) * | 2016-09-02 | 2018-03-08 | 三菱ケミカルフーズ株式会社 | Composition and method for sterilizing spore-forming bacteria |
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| JP7479624B2 (en) | 2020-03-23 | 2024-05-09 | 株式会社トクヤマデンタル | Weakly acidic hypochlorous acid disinfectant composition containing rust inhibitor |
| AU2022306199A1 (en) * | 2021-07-06 | 2024-02-15 | Sun Hope Co., Ltd. | Microbial treatment solution and method of producing microbial treatment solution |
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| WO2007061236A1 (en) * | 2005-11-23 | 2007-05-31 | Republic Of Korea(Management : Rural Development Administration) | Cleaner for precaution against of cow's hoof, manufacturing method thereof, and using method thereof |
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