JP3544311B2 - Injection nozzle cap - Google Patents
Injection nozzle cap Download PDFInfo
- Publication number
- JP3544311B2 JP3544311B2 JP33932398A JP33932398A JP3544311B2 JP 3544311 B2 JP3544311 B2 JP 3544311B2 JP 33932398 A JP33932398 A JP 33932398A JP 33932398 A JP33932398 A JP 33932398A JP 3544311 B2 JP3544311 B2 JP 3544311B2
- Authority
- JP
- Japan
- Prior art keywords
- injection nozzle
- nozzle cap
- luer lock
- leg
- air flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3104—Caps for syringes without needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3106—Plugs for syringes without needle
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
【０００１】
【発明の属する技術分野】
本発明はルアーロックを有するプレフィルド注射器（ｐｒｅ−ｆｉｌｌｅｄ ｓｙｒｉｎｇｅ）のノズルキャップに関し、詳しくは打栓時のノズルキャップの浮き上りが防止されたプレフィルド注射器のノズルキャップに関する。
【０００２】
【従来の技術】
近年、薬液や栄養剤等を予め注射器の注射筒内に充填、密封した容器兼用注射器がプレフィルド注射器と称されて使用されるようになってきた。容器兼用注射器の使用によって、アンプルやバイアル等の容器から薬液等を注射器に吸引する際の誤操作、異物混入汚染や注射針の損傷等が防止でき、更に、緊急時の揺変性（チクソトロピック性を有する）薬液等を注射器へ吸引する手間や時間を省くことが可能となった。
【０００３】
プレフィルド注射器には、輸液等に薬剤を混合したり、粘性の高い薬剤等を注射するために、エクステンションチューブ（延長チューブ）や三方コックあるいは注射針を接続するためのルアーロック部が該注射器の頭部に形成されているものも用いられる。
プレフィルド注射器のルアーロック部について図１を参照して説明する。図１はルアーロック部の断面図（左半分）と側面図（右半分）を同時に示している。ルアーロック部は注射ノズル及びこれを取囲む該注射ノズルよりは高さの低い該注射ノズルと同心円の円筒から構成され、該円筒の内周面には凸状螺旋突条が形成されており、該注射ノズルとルアーロック部とエクステンションチューブ等を接続するための、中心には注射ノズルに嵌挿する孔とルアーロック部の凸状螺旋突条と螺合させる凸状螺旋突条が外面に形成された円筒状接続部が該注射ノズルとルアーロック部の間隙にねじ込み嵌合される。
【０００４】
薬液等をプレフィルド注射器に充填する際には上記の注射ノズル及びルアーロック部に注射ノズルキャップが装着される。この注射ノズルキャップの装着操作は通常打栓と称される。注射ノズルキャップが打栓されたプレフィルド注射器は加熱滅菌処理される。
従来から使用されているルアーロック部を有するプレフィルド注射器用のノズルキャップは、ルアーロック部の円筒外周面に被せる外側円筒と注射ノズルの少なくとも先端部に被せる内側円筒とが天面部下方にそれぞれ形成されたゴム栓が用いられている。このような構造のノズルキャップをルアーロック部及び注射ノズルに被せた状態の一例の断面図を図２に示す（但し、ルアーロック部の外側円筒部内周面の凸状螺旋突条は省略してある）。又、ノズルキャップ打栓開始時の概略断面図を図３に、ある程度打栓が進行した状態の概略断面図を図４に示す。ノズルキャップの打栓が完了すると、ノズルキャップと注射ノズル及びルアーロック部との間隙部には、打栓中に逃げきれない空気が加圧されて密閉されるためにノズルキャップは浮き上がり易い状態となる。
従って、このような加圧空気が密閉された浮き上がり易いノズルキャップが打栓されたプレフィルド注射器を加熱滅菌処理すると、加熱によって密閉された加圧空気は更に膨張して内部圧が上昇し、ノズルキャップを逆に浮き上がらせることとなり、ノズルキャップは抜け易くなるという問題があった。
【０００５】
【発明が解決しようとする課題】
本発明の目的は、ルアーロック部を有するプレフィルド注射器に注射ノズルキャップを打栓する際に注射ノズルキャップの先端とそれが嵌装されるルアーロック部及び注射ノズルとの間隙で形成される空間に加圧空気が密閉されることが防止され、注射ノズルキャップが打栓された該注射器を加熱滅菌する際の加熱による密閉空気の更なる圧上昇による注射ノズルキャップの浮き上がりが防止され、注射ノズルの密封が保持されるルアーロック部を有するプレフィルド注射器用のノズルキャップを提供することである。
【０００６】
本発明者は、上記目的を達成すべき種々検討した結果、従来の図２に示す注射ノズルキャップにおける外側円筒部は注射ノズルの密封には実質的に寄与しておらず、内側円筒だけで十分であること、そして内側円筒のルアーロック部の円筒内面と接触する面に空気の抜け道を設けることで上記空間に存在する空気は打栓とともに大気中に排出されて加圧空気の密閉は防止され、打栓時及び加熱滅菌時の注射ノズルキャップの浮き上がりは防止され、注射ノズルの密封性が保持されることを見出し本発明を完成するに至った。
【０００７】
【課題を解決するための手段】
上記の発明の目的は以下の本発明によって達成される。即ち、本発明は、ルアーロックを有するプレフィルド注射器の注射ノズルと円筒状ルアーロック部との間隙に嵌挿する天面部と円筒状脚部とからなる注射ノズルキャップにおいて、該注射ノズルキャップ嵌挿時に形成される上記間隙と該注射ノズルキャップ脚部先端との空間を大気と連通させる空気流通路が該注射ノズルキャップ脚部外面に形成されていることを特徴とする注射ノズルキャップである。
【０００８】
【発明の実施の形態】
次に発明の実施の形態を挙げて本発明を更に詳細に説明する。
本発明の注射ノズルキャップは、ルアーロック部を有するプレフィルド注射器の注射ノズルと円筒状ルアーロック部との間隙に嵌挿されて使用される天面部と脚部とからなるほぼ円筒状のゴム栓である。円筒状脚部の内径は注射ノズルの外径より小さく、注射ノズルを挿入することにより押し広げられることで密封性が保持される。又、脚部外面はルアーロック部の円筒内面に圧接されるが、これもノズルキャップの密封性保持にも与っているが、ノズルキャップの抜け落ちを防止する効果がある。
【０００９】
又、注射ノズルキャップを嵌挿する際の上記の間隙と注射ノズルキャップ脚部の先端とで形成される空間に存在する空気は、注射ノズルキャップの円筒状脚部外面に形成された該空間と大気とを連通させる空気流通路を逃げ道として打栓の進行とともに大気中に排出され、加圧空気が該空間に密閉されることは防止される。
ノズルキャップ外面に形成される空気の抜け道となる空気流通路は、注射ノズルキャップ脚部の外面がルアーロック部の円筒内面と圧接しても塞がれずに打栓とともに前記空間の空気を大気中に逃がせるように大気と連通可能に形成されておればよく、構造、形状等は特に制限されない。
【００１０】
図５及び図６にその脚部外面に空気流通路が形成された注射ノズルキャップを打栓する状態の概略断面図を示す。図５は打栓直後の状態であり、注射ノズルと円筒状ルアーロック部との間隙と注射ノズルキャップ先端とで形成される空間に空気が存在している状態を示している。図６は上記空間の空気は、打栓の進行とともに注射ノズルキャップ脚部外面の空気流通路から大気中に排出され、前記空間に加圧空気が密閉されることがないことを示している。従って、打栓が終了した時点においても注射ノズルキャップが浮き上がり易くなることはなく、注射ノズルキャップが打栓されたプレフィルド注射器を加熱滅菌処理しても、注射ノズルキャップの浮き上がりは起こらず、注射ノズルの密封性は確実となる。
【００１１】
空気流通路としては、例えば、注射ノズルキャップ脚部外面の長手方向に沿って天面部下端から脚部先端にわたって形成された少なくとも１本の線状凸状部が挙げられる。この場合には、該凸状部、該凸状部のない注射ノズルキャップ脚部外面及びルアーロック部円筒内面とで形成される間隙が前記空間と大気とを連通させる空気流通路となる。該凸状部を複数形成する場合にはそれぞれの間隔を適当に取り、上記間隙の形成を確実なものとすることが望ましい。該凸状部の断面形状及び大きさは、該凸状部がルアーロック部の円筒内面と圧接したときに上記の間隙が形成されるように、本数及び該凸状部間の間隔とともに適宜きめればよく特に限定されない。又、該凸状部は連続して線状であればよく、脚部の長手方向に平行、斜め向き、螺旋状等任意である。
【００１２】
他の例としては、上記の該凸状部に代えて線状の凹部溝を形成する例が挙げられる。該溝の断面形状、溝深さ、溝間隔、本数等も上記と同様である。
これらの例では、必要により、注射ノズルキャップの天面部裏面（脚部側）にも脚部の空気流通路に接続して上記同様の空気流通路を形成することもできる。
又、上記以外の例としては、多数の凸状突起を適当な間隔で形成する例である。前記の空間と大気とが連通するように凸状突起の形状、大きさ及び高さ、個数、配置等は適宜決定される。
【００１３】
本発明の注射ノズルキャップは以上のような空気流通路を脚部外面に形成すること以外は従来の注射ノズルキャップと同様にして製造される。本発明の注射ノズルキャップの製造に用いられるゴム原料及び配合剤等も従来の注射ノズルキャップや医薬品及び医療用ゴム栓の製造に用いられているものはいずれも使用でき、これらも特に限定されない。又、注射ノズルキャップの脚部内面をそれと注射器の内容物とが直接接触することを防止するために、従来の注射ノズルキャップや医薬品及び医療用ゴム栓と同様にその内面をフッ素系樹脂等の樹脂フィルムで被覆することもできる。
【００１４】
【実施例】
本発明の実施例を図面を参照して説明する。
図７に本発明の注射ノズルキャップの一例の斜視図を示す。この例は、空気流通路を形成するためにノズルキャップ脚部外面の長手方向に平行に、断面形状が曲面の直線状凸部がほぼ等間隔に６本形成されたものである。
図８は上記注射ノズルキャップをルアーロック部を有するプレフィルド注射器の注射ノズルと円筒状ルアーロック部の間隙に嵌挿した状態の平面図である。但し、注射ノズルの天面部は除いてある。該凸状部はルアーロック部の円筒内面と圧接して圧縮されているが、空気流通路は該凸状部と該凸状部間の該円筒内面及び該凸状部のない注射ノズル脚部外面とで形成された間隙に、注射ノズルとルアーロック部と注射ノズルキャップ脚部先端とで形成される空間と大気を連通させるように形成されている。
従って、プレフィルド注射器に上記注射ノズルキャップを打栓する際にも、又、該注射ノズルキャップが打栓された該注射器を加熱滅菌処理した際にも該注射ノズルキャップの浮き上りは全く起こらなかった。
【００１５】
他の実施例として、上記と同様の形状を有し、その脚部外面に、その長手方向に、ほぼ等間隔に４本の線状凹状（断面形状は半円状）空気流通路を脚部先端から天面部まで及び天面部裏面に脚部の空気流通路と連続した同じ空気流通路を形成した注射ノズルキャップを作製した。その斜視図を図９（１）に、空気流通路を含む天面部及び脚部の一部の断面図を（２）に示す。
プレフィルド注射器に上記注射ノズルキャップを打栓し、又、この該注射器を加熱滅菌処理した。打栓時及び加熱滅菌処理時にも該注射ノズルキャップの浮き上りは全く起こらなかった。
【００１６】
【発明の効果】
以上の本発明によれば、打栓時の注射ノズルの浮き上り易さも起こらず、注射ノズルキャップが打栓されたルアーロック部を有する注射器を加熱滅菌処理した場合にも注射ノズルキャップの浮き上りが防止されたルアーロック部を有するプレフィルド注射器用の注射ノズルキャップが提供される。本発明の注射ノズルキャップを使用することによって該注射器の注射ノズルの密封性を確実なものとすることができる。
【図面の簡単な説明】
【図１】ルアーロックを有する注射器の頭部を示す図である。
【図２】ルアーロックを有する注射器用の従来の注射ノズルキャップを示す図である。
【図３】従来の注射ノズルキャップにおける打栓を説明する図である。
【図４】従来の注射ノズルキャップにおける打栓を説明する図である。
【図５】本発明の注射ノズルキャップにおける打栓を説明する図である。
【図６】本発明の注射ノズルキャップにおける打栓を説明する図である。
【図７】実施例の注射ノズルキャップの斜視図である。
【図８】実施例の注射ノズルキャップを装着した注射器の平面図である。
【図９】（１）は他の実施例の注射ノズルキャップの斜視図、（２）は一部の断面図である。[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a nozzle cap of a pre-filled syringe having a luer lock, and more particularly, to a nozzle cap of a pre-filled syringe in which the nozzle cap is prevented from floating when plugged.
[0002]
[Prior art]
2. Description of the Related Art In recent years, a container dual-use syringe, which has been previously filled in a syringe of a syringe with a drug solution, a nutrient, and the like, and sealed, has been used as a prefilled syringe. The use of a container-and-syringe can prevent erroneous operations when suctioning a medicinal solution, etc. from a container such as an ampoule or vial into a syringe, contamination of foreign matter or damage to a syringe needle. In addition, thixotropic properties (thixotropic properties) in an emergency can be prevented. It has become possible to save time and effort for sucking a drug solution or the like into a syringe.
[0003]
The prefilled syringe is equipped with an extension tube (extension tube), a three-way cock, or a luer lock for connecting a syringe needle to the head of the syringe in order to mix a drug into an infusion or to inject a highly viscous drug. What is formed in the part is also used.
The luer lock of the prefilled syringe will be described with reference to FIG. FIG. 1 shows a sectional view (left half) and a side view (right half) of the luer lock portion at the same time. The luer lock portion is composed of an injection nozzle and a cylinder that is concentric with the injection nozzle that is lower than the injection nozzle that surrounds the injection nozzle, and a convex spiral ridge is formed on the inner peripheral surface of the cylinder, In order to connect the injection nozzle, the luer lock portion, the extension tube, etc., at the center, a hole to be inserted into the injection nozzle and a convex spiral ridge to be screwed with the convex spiral ridge of the luer lock portion are formed on the outer surface. The formed cylindrical connection portion is screwed into the gap between the injection nozzle and the luer lock portion.
[0004]
When filling the prefilled syringe with a drug solution or the like, an injection nozzle cap is attached to the injection nozzle and the luer lock. This mounting operation of the injection nozzle cap is usually called stoppering. The prefilled syringe with the injection nozzle cap stoppered is heat sterilized.
A conventionally used nozzle cap for a prefilled syringe having a luer lock portion has an outer cylinder that covers the outer peripheral surface of the cylinder of the luer lock portion and an inner cylinder that covers at least the distal end portion of the injection nozzle, which are respectively formed below the top surface portion. Rubber stoppers are used. FIG. 2 is a cross-sectional view showing an example of a state in which the nozzle cap having such a structure is put on the luer lock portion and the injection nozzle (however, the convex spiral ridge on the inner peripheral surface of the outer cylindrical portion of the luer lock portion is omitted). is there). FIG. 3 is a schematic cross-sectional view at the start of nozzle cap plugging, and FIG. 4 is a schematic cross-sectional view of the state in which plugging has progressed to some extent. When plugging of the nozzle cap is completed, air that cannot escape during plugging is pressurized and sealed in the gap between the nozzle cap and the injection nozzle and the luer lock, so that the nozzle cap is easily lifted. Become.
Therefore, when a pre-filled syringe in which such a pressurized air-sealed nozzle cap that is easily lifted is plugged is heated and sterilized, the pressurized air that is closed by heating is further expanded to increase the internal pressure, and the nozzle cap is raised. On the other hand, there is a problem that the nozzle cap is easily pulled out.
[0005]
[Problems to be solved by the invention]
An object of the present invention is to provide a space formed by a gap between a tip of an injection nozzle cap, a luer lock portion into which it is fitted, and an injection nozzle when the injection nozzle cap is plugged into a prefilled syringe having a luer lock portion. The pressurized air is prevented from being sealed, and the injection nozzle cap is prevented from being lifted due to a further increase in the pressure of the sealed air due to heating when the syringe with the injection nozzle cap plugged is heated and sterilized. It is an object of the present invention to provide a nozzle cap for a prefilled syringe having a luer lock in which the seal is maintained.
[0006]
As a result of various studies to achieve the above object, the present inventors have found that the outer cylindrical portion of the conventional injection nozzle cap shown in FIG. 2 does not substantially contribute to the sealing of the injection nozzle, and the inner cylinder alone is sufficient. By providing an air vent on the surface of the inner cylinder that is in contact with the inner surface of the luer lock part, the air present in the space is discharged into the atmosphere together with the stopper and the pressurized air is prevented from being sealed. The present inventors have found that the injection nozzle cap is prevented from lifting during tapping and heat sterilization, and that the sealing performance of the injection nozzle is maintained, thereby completing the present invention.
[0007]
[Means for Solving the Problems]
The object of the invention described above is achieved by the following invention. That is, the present invention relates to an injection nozzle cap including a top surface portion and a cylindrical leg portion to be inserted into a gap between an injection nozzle of a prefilled syringe having a luer lock and a cylindrical luer lock portion, when the injection nozzle cap is inserted. An injection nozzle cap, wherein an air flow passage for communicating a space between the formed gap and the tip of the injection nozzle cap leg with the atmosphere is formed on an outer surface of the injection nozzle cap leg.
[0008]
BEST MODE FOR CARRYING OUT THE INVENTION
Next, the present invention will be described in more detail with reference to embodiments of the present invention.
The injection nozzle cap of the present invention is a substantially cylindrical rubber stopper having a top surface portion and a leg portion used by being inserted into a gap between the injection nozzle of a prefilled syringe having a luer lock portion and a cylindrical luer lock portion. is there. The inner diameter of the cylindrical leg portion is smaller than the outer diameter of the injection nozzle, and the sealing performance is maintained by inserting the injection nozzle and expanding it. Further, the outer surface of the leg portion is pressed against the inner surface of the cylinder of the luer lock portion, which also has an effect of maintaining the sealing performance of the nozzle cap, but has an effect of preventing the nozzle cap from falling off.
[0009]
In addition, air existing in the space formed by the gap when the injection nozzle cap is inserted and the tip of the injection nozzle cap leg is separated from the space formed on the outer surface of the cylindrical leg of the injection nozzle cap. An air flow passage communicating with the atmosphere is used as an escape route, and is discharged into the atmosphere with the progress of tapping, so that pressurized air is prevented from being sealed in the space.
The air flow passage which is formed on the outer surface of the nozzle cap and serves as a passage for air is not closed even when the outer surface of the injection nozzle cap leg is pressed against the inner surface of the cylinder of the luer lock portion. The structure, shape, and the like are not particularly limited as long as they are formed so as to be able to communicate with the atmosphere so that they can escape to the air.
[0010]
5 and 6 are schematic cross-sectional views showing a state in which the injection nozzle cap having the air flow passage formed on the outer surface of the leg is plugged. FIG. 5 shows a state immediately after stoppering, in which air is present in a space formed by the gap between the injection nozzle and the cylindrical luer lock and the tip of the injection nozzle cap. FIG. 6 shows that the air in the space is discharged into the atmosphere from the air flow passage on the outer surface of the injection nozzle cap leg as the tapping progresses, and the pressurized air is not sealed in the space. Therefore, the injection nozzle cap is not easily lifted even after the stoppering is completed, and even if the prefilled syringe with the stoppered injection nozzle cap is heated and sterilized, the injection nozzle cap does not lift, and the injection nozzle cap does not rise. Is assured of hermeticity.
[0011]
The air flow path includes, for example, at least one linear convex portion formed from the lower end of the top surface portion to the tip of the leg along the longitudinal direction of the outer surface of the injection nozzle cap leg. In this case, a gap formed between the convex portion, the outer surface of the injection nozzle cap leg portion without the convex portion, and the inner surface of the luer lock portion cylinder serves as an air flow passage for communicating the space with the atmosphere. When a plurality of the convex portions are formed, it is preferable that the intervals are appropriately set to ensure the formation of the gap. The cross-sectional shape and size of the convex portions are appropriately determined together with the number and the interval between the convex portions so that the above-mentioned gap is formed when the convex portion is pressed against the inner surface of the cylinder of the luer lock portion. There is no particular limitation as long as it is sufficient. In addition, the convex portion may be a continuous linear shape, and may be parallel, oblique, spiral, or the like in the longitudinal direction of the leg portion.
[0012]
As another example, there is an example in which a linear concave groove is formed instead of the above-mentioned convex portion. The cross-sectional shape, groove depth, groove interval, number, and the like of the grooves are the same as described above.
In these examples, if necessary, an air flow passage similar to the above can also be formed by connecting to the air flow passage of the leg also on the back surface (leg side) of the top surface of the injection nozzle cap.
Another example other than the above is an example in which a large number of convex protrusions are formed at appropriate intervals. The shape, size, height, number, arrangement, and the like of the projections are determined as appropriate so that the space communicates with the atmosphere.
[0013]
The injection nozzle cap of the present invention is manufactured in the same manner as the conventional injection nozzle cap except that the air flow passage as described above is formed on the outer surface of the leg. The rubber raw materials and compounding agents used in the production of the injection nozzle cap of the present invention can be any of those used in the production of conventional injection nozzle caps and rubber stoppers for medicines and medical supplies, and these are not particularly limited either. Also, in order to prevent the inner surface of the leg of the injection nozzle cap from coming into direct contact with the contents of the syringe, the inner surface of the injection nozzle cap is made of a fluororesin or the like in the same manner as a conventional injection nozzle cap or a medical and medical rubber stopper. It can also be covered with a resin film.
[0014]
【Example】
Embodiments of the present invention will be described with reference to the drawings.
FIG. 7 shows a perspective view of an example of the injection nozzle cap of the present invention. In this example, six linear projections having a curved cross section are formed at substantially equal intervals in parallel with the longitudinal direction of the outer surface of the nozzle cap leg to form an air flow passage.
FIG. 8 is a plan view showing a state in which the injection nozzle cap is inserted into a gap between an injection nozzle of a prefilled syringe having a luer lock and a cylindrical luer lock. However, the top surface of the injection nozzle is not shown. The protruding portion is compressed by being pressed against the inner surface of the cylinder of the luer lock portion, but the air flow passage is formed between the protruding portion and the inner surface of the cylinder between the protruding portions and the injection nozzle leg without the protruding portion. A space formed by the outer surface and the space formed by the injection nozzle, the luer lock portion, and the tip of the injection nozzle cap leg is formed to communicate with the atmosphere.
Therefore, no lifting of the injection nozzle cap occurred when the injection nozzle cap was plugged into a pre-filled syringe or when the syringe with the injection nozzle cap plugged was subjected to heat sterilization. .
[0015]
As another embodiment, four linear concave (semicircular cross-sectional shapes) air flow passages having the same shape as described above and having substantially equal intervals in the longitudinal direction thereof are formed on the outer surfaces of the legs. An injection nozzle cap was formed in which the same air flow path that was continuous with the air flow path of the leg was formed from the tip to the top surface and on the back surface of the top surface. FIG. 9A is a perspective view thereof, and FIG. 9B is a cross-sectional view of a part of the top surface portion and the leg portion including the air flow passage.
The injection nozzle cap was plugged into a prefilled syringe, and the syringe was heat-sterilized. No lifting of the injection nozzle cap occurred at the time of stoppering or heat sterilization.
[0016]
【The invention's effect】
According to the present invention described above, the injection nozzle does not easily float when plugged, and the injection nozzle cap also rises when the syringe having the luer lock portion in which the injection nozzle cap is plugged is heat-sterilized. There is provided an injection nozzle cap for a prefilled syringe having a luer lock portion in which is prevented. By using the injection nozzle cap of the present invention, the sealing performance of the injection nozzle of the syringe can be ensured.
[Brief description of the drawings]
FIG. 1 shows the head of a syringe with a luer lock.
FIG. 2 shows a conventional injection nozzle cap for a syringe having a luer lock.
FIG. 3 is a view for explaining stoppering in a conventional injection nozzle cap.
FIG. 4 is a view for explaining stoppering in a conventional injection nozzle cap.
FIG. 5 is a view for explaining stoppering in the injection nozzle cap of the present invention.
FIG. 6 is a view for explaining stoppering in the injection nozzle cap of the present invention.
FIG. 7 is a perspective view of the injection nozzle cap of the embodiment.
FIG. 8 is a plan view of a syringe equipped with the injection nozzle cap of the embodiment.
FIG. 9 (1) is a perspective view of an injection nozzle cap of another embodiment, and (2) is a partial cross-sectional view.
Claims (4)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33932398A JP3544311B2 (en) | 1998-11-30 | 1998-11-30 | Injection nozzle cap |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33932398A JP3544311B2 (en) | 1998-11-30 | 1998-11-30 | Injection nozzle cap |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000157630A JP2000157630A (en) | 2000-06-13 |
| JP3544311B2 true JP3544311B2 (en) | 2004-07-21 |
Family
ID=18326379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP33932398A Expired - Lifetime JP3544311B2 (en) | 1998-11-30 | 1998-11-30 | Injection nozzle cap |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3544311B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009219855A (en) * | 2008-02-19 | 2009-10-01 | Arte Corp | Syringe-cum-container |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| JP5265666B2 (en) * | 2008-04-01 | 2013-08-14 | 生化学工業株式会社 | Chemical liquid discharge part sealing cap |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| WO2012162259A2 (en) | 2011-05-20 | 2012-11-29 | Excelsior Medical Corporation | Caps for cannula access devices |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| CN106902405B (en) | 2011-07-12 | 2020-12-11 | Icu医学有限公司 | Device for delivering antimicrobial agents into a percutaneous catheter |
| ES2755352T3 (en) | 2014-05-02 | 2020-04-22 | Excelsior Medical Corp | Strip pack for antiseptic cap |
| EP3294404A4 (en) | 2015-05-08 | 2018-11-14 | ICU Medical, Inc. | Medical connectors configured to receive emitters of therapeutic agents |
| SI3525865T1 (en) | 2016-10-14 | 2023-01-31 | Icu Medical, Inc. | Sanitizing caps for medical connectors |
| WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
| WO2019111613A1 (en) * | 2017-12-06 | 2019-06-13 | 住友ゴム工業株式会社 | Tip cap |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| JP2022513096A (en) | 2018-11-21 | 2022-02-07 | アイシーユー・メディカル・インコーポレーテッド | Antibacterial device with cap with ring and insert |
| CN112429399A (en) * | 2020-11-23 | 2021-03-02 | 石家庄禾柏生物技术股份有限公司 | Sealing cover |
| JP2024500319A (en) | 2020-12-07 | 2024-01-09 | アイシーユー・メディカル・インコーポレーテッド | Peritoneal dialysis cap, system, and method |
| CN113679913A (en) * | 2021-07-09 | 2021-11-23 | 贵州三力制药股份有限公司 | Cap structure for preventing liquid from leaking outwards of spraying agent medicine bottle |
-
1998
- 1998-11-30 JP JP33932398A patent/JP3544311B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009219855A (en) * | 2008-02-19 | 2009-10-01 | Arte Corp | Syringe-cum-container |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000157630A (en) | 2000-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3544311B2 (en) | Injection nozzle cap | |
| EP0609741B1 (en) | Prefilled syringe assembly | |
| KR102659029B1 (en) | Tip cap assembly for closing an injection system | |
| US4484916A (en) | Medical solution container and port construction | |
| JP4582983B2 (en) | Connected device ready for use | |
| KR960005816B1 (en) | Anti-needle strike and anti-drug abuse syringe | |
| US5409125A (en) | Unit dose container | |
| US6287289B1 (en) | Multiple use universal connector | |
| US4543093A (en) | Variable sealing pressure plunger rod assembly | |
| US6632199B1 (en) | Syringe assembly including plastic tip cap | |
| JP3763141B2 (en) | Syringe type chemical container | |
| AU2006301180B2 (en) | Syringe for administering multiple doses, comprising an injection needle with sterility protection | |
| ES2535533T3 (en) | Plastic capsule and its production method | |
| US4592092A (en) | Medical solution container and port construction therefor | |
| CA2262475A1 (en) | Multiple use universal connector | |
| JPH09225029A (en) | Injector and its manufacture | |
| WO2008059863A1 (en) | Injection nozzle cap | |
| JP4372363B2 (en) | Sealed rubber stopper for syringe and container | |
| CN101332326A (en) | Closed type re-use preventing once-used syringe | |
| US11612693B1 (en) | Method and apparatus to reduce the deadspace in syringes and small-bore devices | |
| KR20160002806U (en) | Connector for Intravenous Infusion | |
| JP4299509B2 (en) | Prefilled syringe and prefilled syringe | |
| JPH0422745Y2 (en) | ||
| JP4098593B2 (en) | Container / Syringe | |
| CN208877565U (en) | A kind of syringe of pre-packaged lidocaine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20040128 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20040330 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20040401 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090416 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090416 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100416 Year of fee payment: 6 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100416 Year of fee payment: 6 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110416 Year of fee payment: 7 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110416 Year of fee payment: 7 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120416 Year of fee payment: 8 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130416 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130416 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140416 Year of fee payment: 10 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |