JP2022129859A - Analysis device and control program thereof - Google Patents

Abstract

To improve visibility of a time change curve of signal intensity of an ultrasonic wave reflected from a contrast medium injected to a subject.SOLUTION: A processor of an analysis device reads out data indicating signal intensity of an ultrasonic wave reflected by a contrast medium from a memory, and calculates data on a representative value of the signal intensity for each of a plurality of data groups D. The processor creates a time change curve T of the signal intensity of the ultrasonic wave based on the data read out from the memory and the data on the representative value, and displays it in a display unit. In the time change curve T, adjacent data groups D in a time axis direction are connected by the data on the representative value of each of the data groups D.SELECTED DRAWING: Figure 4

Description

The present invention relates to an analysis apparatus and its control program for creating a time change curve of signal intensity of ultrasonic waves reflected by a contrast medium injected into a subject.

2. Description of the Related Art An ultrasonic diagnostic apparatus may create a contrast-enhanced image that indicates the signal intensity of ultrasonic waves reflected by a contrast medium injected into a subject. Also, a time change curve may be created within a region of interest (ROI) set in a contrast image (see Patent Document 1, for example). This time change curve indicates the time change of signal intensity in the region of interest, and is also called TIC (Time Intensity Curve). Differential diagnosis of tumors can be made by the characteristics of the time-varying curves.

WO2018/87198

New diagnostic information can be obtained by observing changes in the signal intensity of the ultrasound reflected by the contrast agent for a relatively long period of time, such as 5 or 10 minutes after the administration of the contrast agent. is being understood. For example, the degree to which a contrast agent in a liver tumor flows out is called washout. It is said that the complexity of the vascular structure and vascular resistance can be estimated. In addition, the contrast medium accumulated in the liver parenchyma may be able to quantify the liver function by comparing immediately after administration and 5 minutes and 10 minutes after administration.

In order to perform the above analysis, it is necessary to collect data for a relatively long time after administration of the contrast agent. In this regard, in the X-ray CT and MRI systems, the subject lies in the gantry of the equipment, and the entire organ is stereoscopically imaged. Imaging becomes possible. On the other hand, in the ultrasonic diagnostic apparatus, the examiner must hold the ultrasonic probe and keep tracking the region of interest (section). In addition, since it is difficult for the subject to hold his or her breath for a long time, the subject continues to take small breaths. For this reason, the examiner continues to hold the ultrasonic probe while the region of interest is undergoing respiratory fluctuations, which is a burden on the examiner.

Techniques for reducing the burden on the examiner and the subject as described above have been proposed. For example, if you want to observe the change in signal intensity from the contrast agent for 10 minutes, instead of performing ultrasonic scanning and image recording continuously for 600 seconds, after 2 minutes, 3 minutes, ... 10 minutes After that, short-time moving images such as 5 seconds each are captured to obtain intermittent data. However, for 0 to 60 seconds immediately after contrast agent administration, moving images may be continuously captured as usual. Then, the examiner individually performs TIC analysis on the acquired data after 1 minute, 2 minutes, 3 minutes, . . . , 10 minutes. displayed as Each image is stamped with the time it was taken, thus preserving the accuracy of the time axis. With this method, after two minutes, it is sufficient to concentrate on image acquisition for a short period of time, which reduces the burden on both the examiner and the subject.

However, if a TIC is created based on such intermittently obtained data, the last data in a relatively short time of 5 seconds after 2 minutes, for example, and the first data after 3 minutes are connected. The graph becomes unnatural.

An analysis device according to one aspect includes a processor, a display, and a memory, and the memory stores data indicating the signal strength of ultrasound waves transmitted to a subject injected with a contrast agent and reflected by the contrast agent. This data includes data acquired intermittently over a required length of time to form a plurality of data groups. The processor reads out data from the memory and calculates representative value data of the signal strength for each of the plurality of data groups. Then, the processor provides a time change curve of the ultrasonic signal intensity based on the data read from the memory and the data of the representative value, wherein the interval between the data groups adjacent in the time axis direction is the representative value for each of the data groups are created and displayed on the display.

According to the analysis device of the above aspect, a time change curve is created and displayed in which data groups adjacent to each other in the time axis direction are connected by representative value data for each of the data groups. Thereby, the visibility of the time change curve can be improved.

1 is a block diagram illustrating an exemplary ultrasound diagnostic apparatus in accordance with various aspects described herein; FIG. FIG. 4 is an explanatory diagram of a plurality of data groups; 4 is a flowchart showing an example of processing for creating a time change curve according to the embodiment; It is a figure which shows an example of a time change curve. FIG. 10 is a flowchart showing an example of details of processing for creating a time change curve; FIG. FIG. 10 is an explanatory diagram of a data group before addition of representative value data; FIG. 10 is an explanatory diagram of a data group after data of representative values are added; FIG. 11 shows a time-varying curve compared with a time-varying curve according to an embodiment; FIG. 11 is an explanatory diagram of a data group after data of representative values are added in a modified example; FIG. 10 is a diagram illustrating an example of a system according to a second embodiment; FIG.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, embodiments of the present invention will be described with reference to the drawings.
(First embodiment)
First, the first embodiment will be described. An ultrasonic diagnostic apparatus 1 shown in FIG. 1 is an example of an analysis apparatus that creates a time change curve T, which will be described later. An ultrasound diagnostic apparatus 1 includes an ultrasound probe 2 , a transmission beamformer 3 and a transmitter 4 . The ultrasonic probe 2 performs an ultrasonic scan on the subject and receives ultrasonic echoes.

More specifically, the ultrasonic probe 2 has a plurality of transducer elements 2a that emit pulsed ultrasonic waves to a subject (not shown). A plurality of transducer elements 2a are driven by a transmit beamformer 3 and a transmitter 4 to radiate pulsed ultrasonic waves.

The ultrasound diagnostic apparatus 1 further includes a receiver 5 and a receive beamformer 6 . The pulsed ultrasonic waves radiated from the transducer 2a generate echoes that are reflected within the subject and return to the transducer 2a. The echo is converted into an electric signal by the transducer 2 a to become an echo signal, which is input to the receiver 5 . The echo signal is amplified by a required gain in the receiver 5 and then input to the reception beamformer 6, where reception beamforming is performed. The receive beamformer 6 outputs ultrasound data after receive beamforming.

The receive beamformer 6 may be a hardware beamformer or a software beamformer. If the receive beamformer 6 is a software beamformer, the receive beamformer 6 may be a graphics processing unit (GPU), a microprocessor, a central processing unit (CPU), a digital signal processor (DSP), or perform logic operations. can comprise one or more processors, including any one or more of the other types of processors that can The processor that configures the receive beamformer 6 may be configured by a processor different from the processor 7 described later, or may be configured by the processor 7 .

The ultrasound probe 2 may include electrical circuitry for performing all or part of the transmit beamforming and/or receive beamforming. For example, all or part of the transmit beamformer 3 , transmitter 4 , receiver 5 and receive beamformer 6 may be provided within the ultrasound probe 2 .

The ultrasound diagnostic apparatus 1 also includes a processor 7 for controlling the transmit beamformer 3 , transmitter 4 , receiver 5 and receive beamformer 6 . Furthermore, the ultrasound diagnostic apparatus 1 includes a display 8, a memory 9 and a user interface 10. FIG.

Processor 7 includes one or more processors. Processor 7 is in electronic communication with ultrasound probe 2 . The processor 7 can control the ultrasound probe 2 to acquire ultrasound data. The processor 7 controls which transducer elements 2 a are active and the shape of the ultrasound beam transmitted from the ultrasound probe 2 . The processor 7 is also in electronic communication with a display 8 so that the processor 7 can process the ultrasound data into ultrasound images for display on the display 8 . The term "electronic communication" can be defined to include both wired and wireless communication. Processor 7 may include a central processing unit (CPU) according to one embodiment. According to other embodiments, processor 7 is a digital signal processor, field programmable gate array (FPGA), graphics processing unit (GPU), or other type of processor capable of performing processing functions. It can contain electronic components. According to other embodiments, processor 7 may include multiple electronic components capable of performing processing functions. For example, processor 7 may include two or more electronic components selected from a list of electronic components including a central processing unit, a digital signal processor, a field programmable gate array, and a graphics processing unit.

Processor 7 may also include a complex demodulator (not shown) that demodulates the RF data. In another embodiment, demodulation can be performed early in the processing chain.

Processor 7 is configured to perform one or more processing operations on the data according to a plurality of selectable ultrasound modalities. As the echo signals are received, the data can be processed in real time during the scanning session. For the purposes of this disclosure, the term "real-time" is defined to include procedures that occur without any intentional delay.

The data can also be temporarily stored in a buffer (not shown) during the ultrasound scan and processed in live or off-line operation rather than in real time. In this disclosure, the term "data" may be used in this disclosure to refer to one or more data sets acquired using the ultrasound diagnostic system 1.

Ultrasound data is processed by processor 7 in other or different mode-related modules (e.g., B-mode, color Doppler, M-mode, color M-mode, spectral Doppler, contrast mode, elastography, TVI, strain, strain rate, etc.). It can be processed to produce ultrasound image data. For example, one or more modules may generate ultrasound images such as B-mode, color Doppler, M-mode, color M-mode, spectral Doppler, contrast mode, elastography, TVI, strain, strain rate, and combinations thereof. can be generated. In particular, in this specification, an ultrasound image generated in contrast mode is also referred to as a contrast-enhanced image.

The image beams and/or image frames may be saved and may record timing information indicating when the data was acquired in memory. The modules may include, for example, a scan conversion module that performs scan conversion operations to convert image frames from coordinate beam space to display space coordinates. A video processor module may be provided that reads image frames from memory and displays the image frames in real time while the subject is being treated. The video processor module can store image frames in an image memory and the ultrasound image is read from the image memory and displayed on the display 8 .

Note that as used herein, the term "image" refers broadly to both the visible image and the data representing the visible image. Also, the term "data" may include raw data, which is ultrasound data before a scan conversion operation, and image data, which is data after a scan conversion operation.

When processor 7 includes multiple processors, the above-described processing tasks performed by processor 7 may be performed by multiple processors. For example, a first processor can be used to demodulate and decimate the RF signal, and a second processor can be used to further process the data before displaying the image.

Also, for example, when the receive beamformer 6 is a software beamformer, its processing function may be executed by a single processor or by a plurality of processors.

The display 8 is an LED (Light Emitting Diode) display, an LCD (Liquid Crystal Display), an organic EL (Electro-Luminescence) display, or the like.

Memory 9 is any known data storage medium. In one example, the ultrasonic diagnostic apparatus 1 includes a non-transitory storage medium and a temporary storage medium as the memory 9 and includes a plurality of memories 9 . A non-transitory storage medium is, for example, a non-volatile storage medium such as an HDD (Hard Disk) and a ROM (Read Only Memory). Non-transitory storage media may include portable storage media such as CDs (Compact Disks) and DVDs (Digital Versatile Disks). A program executed by the processor 7 is stored in the non-transitory storage medium.

A temporary storage medium is a volatile storage medium such as RAM (Random Access Memory).

The user interface 10 can accept operator input. For example, the user interface 10 receives instructions and information input from an operator. The user interface 10 includes a keyboard, hard keys, trackball, rotary control, softkeys, and the like. User interface 10 may include a touch screen that displays soft keys and the like.

Next, the operation of the ultrasonic diagnostic apparatus 1 of this example will be described. As operations, the acquisition of contrast image data and the creation of a time change curve (TIC: Time Intensity Curve) based on the contrast image data will be described.

First, acquisition of contrast image data will be described. The processor 7 controls the ultrasonic probe 2 to transmit ultrasonic waves to the subject. A contrast agent is injected into the subject through which the ultrasound waves are transmitted. The ultrasonic probe 2 receives echoes including ultrasonic waves reflected by the contrast agent. Processor 7 performs known processing on the echo signals to produce data indicative of the signal strength of the ultrasound waves reflected by the contrast agent. The data indicating the signal intensity of the ultrasonic waves reflected by the contrast agent is data of the contrast image. Processor 7 stores the data of the contrast image in memory 9 . This memory 9 may be volatile or non-volatile.

The contrast-enhanced image data stored in the memory 9 is data acquired intermittently over a required length of time. This length of time is the length of time during which breath-holding is difficult for the subject, and in one example is 60 seconds or longer. Echo signals for acquiring contrast image data are acquired while the subject is breathing.

Since the contrast-enhanced image data is acquired intermittently, the contrast-enhanced image data stored in the memory 9 includes a plurality of data groups. For example, the contrast-enhanced image data stored in the memory 9 includes a data group consisting of data up to time t1 after the injection of the contrast agent, and data for s seconds from time t2 (t2>t1) after the injection of the contrast agent. It includes a data group consisting of data and a data group consisting of data for s seconds from the time point t3 (t3>t2) after injection of the contrast medium. However, the contrast-enhanced image data stored in the memory 9 is not limited to three data groups as in the above example, and may include more data groups.

FIG. 2 shows an example of a plurality of data groups D. As shown in FIG. In FIG. 2, the horizontal axis indicates time, and the vertical axis indicates signal intensity. Each point P indicates data constituting a data group.
The data indicated by each point P is one frame of data. The data of one frame is the average value of the signal strength of that frame. Data indicated by individual points P shown in FIG. 2 are average values of one frame in a region of interest set later for convenience of explanation. However, the region of interest does not have to be set when the contrast image data is acquired.

For example, in FIG. 2, the leftmost data group D is the data group from the injection of the contrast medium to the time point t1, and the second data group D from the left is the data group D from the injection of the contrast medium to t2. It is a data group for s seconds from the time point, and the third data group D from the left may be a data group for s seconds from the time point t3 after injection of the contrast medium. However, in FIG. 2, t1 to t3 are omitted. In FIG. 2, the data group D also exists after time t3.

For example, if the data group D shown in FIG. 2 was acquired intermittently for 10 minutes, the leftmost data group D is data for 60 seconds after the contrast agent was injected. , and subsequent data group D may be data for 5 seconds. However, it goes without saying that the length of time shown here is only an example.

A plurality of data groups may be stored in the memory 9 as a plurality of files in which data is stored. However, the data storage form is not limited to this.

Next, creation of a time change curve will be described based on the flowchart of FIG. First, in step S<b>1 , the processor 7 reads the contrast image data stored in the memory 9 . The data of the contrast-enhanced image to be read includes a plurality of data groups. Also, the processor 7 displays on the display 8 a contrast image based on the read data.

The processor 7 may read the data of the contrast-enhanced image when the user interface 10 receives a user's input to display the contrast-enhanced image. The processor 7 may also display on the display 8 a contrast image based on the read data. In one example, the contrast-enhanced image displayed on the display 8 is a still image, and is an image of one frame selected from a plurality of frames stored in the memory 9 and read out. In one example, a contrast-enhanced image suitable for setting the region of interest is selected and displayed by the user.

Next, in step S<b>2 , a region of interest is set in the contrast image displayed on the display 8 . The user interface 10 accepts user input for setting a region of interest in the contrast image displayed on the display 8 . When the user interface 10 receives an input, the processor 7 sets a region of interest on the contrast-enhanced image.

Next, at step S3, the processor 7 creates a time change curve T and displays it on the display 8. FIG. FIG. 4 shows an example of the time change curve T displayed on the display 8. As shown in FIG. A time change curve T indicates the time change of the signal intensity of the ultrasound reflected by the contrast agent within the region of interest set in step S2. In FIG. 4, a point P included in each data group D also indicates data such as an average value in the region of interest of one frame as in FIG.

An example of creating the time change curve T will be specifically described based on the flowchart of FIG. In step S31, the processor 7 calculates, for each of the plurality of data groups D, the representative value of the signal intensity of the ultrasonic waves reflected by the contrast agent. A representative value is a value that represents each of the plurality of data groups D, and is, for example, an average value or a median value of values indicated by data in each of the plurality of data groups D. The processor 7 calculates an average value and a median value from the data included in the data group D. FIG.

Next, in step S32, the processor 7 adds the representative value data for each of the plurality of data groups D as the first and last data in each of the plurality of data groups D in time. A more detailed description will be given with reference to FIGS. 6 and 7. FIG. 6 and 7 show one of the plurality of data groups D, and the horizontal axis indicates time. Although the vertical axis is not shown in FIGS. 6 and 7, the direction orthogonal to the horizontal axis indicates the signal strength.

FIG. 6 shows data group D before addition of representative value data. A circled point Ps indicates data included in the data group D, and indicates data before being added. A two-dot chain line indicates a time change curve t that would be created if the representative value data were not added.

FIG. 7 shows the data group D after the representative value data has been added. Triangular points Pt1 and Pt2 indicate the average value, median value, or the like of the values indicated by the added representative value data, that is, the data (points Ps) included in the data group D shown in FIG. A point Pt1 indicates the representative value data added as the first data in the data group D in terms of time. A point Pt2 indicates representative value data added as the first data in the data group D in terms of time. A solid line indicates a time change curve T created by adding representative value data.

Next, at step S33, the processor 7 creates a time change curve T using the data read from the memory 9 at step S1 and the data added at step S32. The processor 7 creates a time change curve T in which data groups D adjacent in the time axis direction are connected by representative value data for each of the data groups D. FIG. More specifically, as shown in FIG. 4, the processor 7 divides the data group D that passes through the point P and is adjacent to the last data and the first data (the point Pt2 and the point Pt2 in FIG. 7) added in step S32. Pt1) to create a time-varying curve T connected by Pt1).

Here, if the adjacent data groups D are connected by the data when the representative value data is not added, an unnatural time change curve t is obtained as shown in FIG. On the other hand, in the time change curve T shown in FIG. 4, adjacent data groups D are connected by points Pt2 and Pt1 (not shown in FIG. 4), so a more natural graph can be obtained. . Therefore, the visibility of the time change curve T is improved, and as a result, it is possible to more accurately perform differential diagnosis of tumors and determination of therapeutic effects.

Next, a modified example of the first embodiment will be described. The processor 7 may create a time change curve T in which data groups D adjacent to each other in the direction of the time axis are connected by one point indicating representative value data. In this case, in one example, the processor 7 adds representative value data indicated by a point Pt to the data group D in step S32, as shown in FIG. In this modification, only one point Pt is added per data group D. In FIG. 9, the point Pt is positioned at the central portion of the time width TW of the data group D. In FIG. However, the position of the point Pt is not limited to this. Although only one data group D is shown in FIG. 9, the processor 7 adds representative value data to each of the plurality of data groups D. FIG.

In step S33, the processor 7 creates a time-varying curve T in which adjacent data groups D are connected to points Pt.

(Second embodiment)
Next, a second embodiment will be described. A system 100 shown in FIG. 10 includes an ultrasonic diagnostic apparatus 1 and a server 101 . The ultrasonic diagnostic apparatus 1 and server 101 are connected via a network 102 .

The ultrasonic diagnostic apparatus 1 has the same configuration as that of the first embodiment, and detailed description of each component is omitted. However, in the second embodiment, the processor 7 of the ultrasonic diagnostic apparatus 1 will be described as the first processor 7 . Although only the first processor 7 is illustrated in FIG. 10 as a component of the ultrasonic diagnostic apparatus 1, the ultrasonic diagnostic apparatus 1 in the second embodiment also includes other components shown in FIG. have.

The server 101 may be a workstation, for example, or may be installed in a management center that manages a plurality of ultrasonic diagnostic apparatuses including the ultrasonic diagnostic apparatus 1 . The server 101 has known server components and includes a second processor 103 , a second display 104 , a second memory 105 and a second user interface 106 .

Acquisition of contrast-enhanced image data and creation of a time change curve in the system 100 of this example will now be described. The basic processing in this example is the same as in the first embodiment, and some of the main processes are different from those in the first embodiment. In the following description, detailed description of the same processing contents as in the first embodiment will be omitted.

Contrast-enhanced image data is acquired by the ultrasonic diagnostic apparatus 1 in the same manner as in the first embodiment. On the other hand, the time change curve T is created by the server 101 . Therefore, the contrast image data acquired by the ultrasonic diagnostic apparatus 1 is transmitted to the server 101 via the network 102 and stored in the second memory 105 . The server 101 is an example of an analysis device that creates the time change curve T. FIG.

In the flowchart of FIG. 3 , the second processor 103 reads the contrast image data stored in the second memory 105 in step S1. The second processor 103 may display a contrast image based on the read data on the second display.

In step S2, when the second user interface 106 receives user input for setting a region of interest in the contrast image displayed on the second display 104, the second processor 103 sets the region of interest.

In step S3, the second processor 103 creates a time change curve T by performing the processes of steps S31 to S33 described in the first embodiment. Also in this second embodiment, the time change curve T may be created in the same manner as in the modification of the first embodiment.

In the second embodiment, raw data may be transmitted from the ultrasonic diagnostic apparatus 1 to the server 101 instead of contrast image data. In this case, the second processor 103 creates contrast-enhanced image data by a known method based on the raw data.

Although the invention has been described with reference to certain specific embodiments, various modifications may be made and equivalents substituted without departing from the scope of the invention. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the invention without departing from its scope. Therefore, it is intended that the invention not be limited to the particular embodiments disclosed, but will include all embodiments that fall within the scope of the appended claims.

In addition, the above embodiment
A control method for an analysis device comprising a processor, a display and a memory, comprising:
The memory stores data indicative of the signal strength of ultrasound waves transmitted to a subject injected with a contrast agent and reflected by the contrast agent, the data being stored for a required length of time. includes data that is intermittently acquired over a period of time and constitutes a plurality of data groups,
The control method is
reading the data from the memory and calculating representative value data of the signal intensity for each of the plurality of data groups by executing a program using the processor;
By executing a program using the processor, a time change curve of the signal intensity of the ultrasonic wave based on the data read from the memory and the data of the representative value, wherein the data group adjacent in the time axis direction The control method of the analysis device may include creating a time change curve connected by the representative value data for each of the data groups and displaying the curve on the display.

1 Ultrasound Diagnostic Apparatus 2 Ultrasound Probe 7 Processor 8 Display 9 Memory 10 User Interface 101 Server 102 Network 103 Second Processor 104 Second Display 105 Second Memory

Claims (9)

An analysis device comprising a processor, a display and a memory,
The memory stores data indicative of the signal strength of ultrasound waves transmitted to a subject injected with a contrast agent and reflected by the contrast agent, the data being stored for a required length of time. includes data that is intermittently acquired over a period of time and constitutes a plurality of data groups,
The processor
reading the data from the memory and calculating representative value data of the signal intensity for each of the plurality of data groups;
A time change curve of the signal intensity of the ultrasonic wave based on the data read from the memory and the data of the representative value, wherein the interval between the data groups adjacent in the time axis direction is the representative of each of the data groups An analysis device configured to create and display on said display a time-varying curve connected by value data. The processor adds the representative value data for each of the plurality of data groups as temporally first and last data in each of the plurality of data groups, and the space between the adjacent data groups is the 2. The analysis apparatus of claim 1, which creates said time-varying curves connected by last and said first data. The processor adds one point indicating the representative value data for each of the plurality of data groups to each of the plurality of data groups, and the representative value data is separated between the adjacent data groups. 2. The analysis apparatus of claim 1, which produces said time-varying curves connected by a single point shown. The analysis device according to any one of claims 1 to 3, wherein said representative value is an average value or a median value of said signal intensities in each of said plurality of data groups. the processor is further configured to display on the display a contrast-enhanced image based on the data indicative of the signal strength of the ultrasound;
The analyzing apparatus according to any one of claims 1 to 4, wherein said time change curve is created for a region of interest set in said contrast image. 6. The analysis device according to claim 1, wherein said plurality of data groups are stored in said memory as a plurality of files containing said data. The analysis device is an ultrasonic diagnostic device, further comprising an ultrasonic probe that transmits ultrasonic waves to a subject injected with a contrast medium and receives echo signals of the ultrasonic waves,
The analysis apparatus according to any one of claims 1 to 6, wherein said processor creates data indicating signal intensity of ultrasonic waves reflected by said contrast agent based on said echo signals of said ultrasonic waves. The analysis device is connected via a network to an ultrasonic diagnostic device including an ultrasonic probe that transmits ultrasonic waves to a subject injected with a contrast agent and receives echo signals of the ultrasonic waves,
The data indicating the signal intensity of the ultrasonic wave reflected by the contrast agent is data created based on the echo signal of the ultrasonic wave received by the ultrasonic probe. Analysis device according to. A control program for an analysis device comprising a processor, a display and a memory,
The memory stores data indicative of the signal strength of ultrasound waves transmitted to a subject injected with a contrast agent and reflected by the contrast agent, the data being stored for a required length of time. includes data that is intermittently acquired over a period of time and constitutes a plurality of data groups,
The control program causes the processor to:
reading the data from the memory and calculating representative value data of the signal intensity for each of the plurality of data groups;
A time change curve of the signal intensity of the ultrasonic wave based on the data read from the memory and the data of the representative value, wherein the interval between the data groups adjacent in the time axis direction is the representative of each of the data groups A control program for an analysis device that executes control including creating a time-varying curve connected by value data and displaying it on the display.

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