JP2019054833A - Medical solution administration device - Google Patents

Abstract

To provide a medical solution administration device in which transfer loss caused when output generated in a motor is transmitted to gears, etc. can be suppressed.SOLUTION: A medical solution administration device 100 according to the present invention includes: an injection unit 11 injecting a medical solution into a living body; a medical solution storage unit 141 communicated with the injection unit and storing the medical solution to be fed to the injection unit; a delivery mechanism 143 moving back and forth in the medical solution storage unit and feeding the medical solution in the medical solution storage unit to the injection unit with the forward/backward movement; and a driving mechanism 131 generating the driving force for moving the delivery mechanism back and forth. The driving mechanism comprises a motor 136 with a rotating output shaft 136a, a first gear 137a transmitting the rotation of the output shaft to the delivery mechanism, and an elastically deformable connection member 138 causing the first gear to rotate in conjunction with the rotation of the output shaft by connecting the first gear to the output shaft.SELECTED DRAWING: Figure 7

Description

  The present invention relates to a chemical solution administration device used for administering a chemical solution into a living body.

  2. Description of the Related Art Conventionally, as a device for administering a drug solution such as insulin, a portable administration device that administers a drug solution over time while attached to the skin of a patient or subject to be administered is known.

  For example, an apparatus described in Patent Document 1 includes a storage container in which a chemical solution is stored, a piston plunger that sends out the chemical solution from the storage container, a feed shaft that moves the piston plunger, and a motor that generates a driving force that moves the feed shaft. And a drive gear for transmitting the output from the motor to the feed shaft.

Japanese Patent No. 5172841

  The drug solution administration device as described above is portable and is designed to be relatively small in consideration of convenience of carrying. Therefore, the motor mounted on the apparatus is similarly small, and the output is relatively small because the size of the motor is relatively small. In a conventional general drug delivery device, the delivery of the drug solution by the plunger is performed by the rotation from the output shaft of the motor being decelerated by the gear, and the rotary motion from the gear being converted into the straight motion by the feed shaft. Made. When the position of the rotation shaft between the output shaft of the motor and the gear or the like is shifted in the drug solution administration device equipped with the motor with a relatively small output as described above, the influence of the transmission loss of the output due to the position shift on the drug solution delivery is affected. There is a problem that it is relatively large.

  In order to eliminate the above-mentioned position shift, it seems that it is necessary to strictly align the two when assembling the gear to the output shaft of the motor. However, considering the variation and cost of each part, it is realistic. I can't say that.

  The present invention has been made to solve the above-described problems, and an object of the present invention is to provide a drug solution administration device capable of suppressing transmission loss when transmitting output generated in a motor to a gear or the like.

  A chemical solution administration device according to the present invention includes an injection unit that injects a chemical solution into a living body, a chemical solution storage unit that communicates with the injection unit and stores a chemical solution to be sent to the injection unit, and moves forward and backward in the chemical solution storage unit. And a drive mechanism for generating a driving force for moving the push mechanism forward and backward. In the present invention, the drive mechanism is interlocked with the rotation of the output shaft by connecting the motor having the output shaft that rotates, the transmission unit that transmits the rotation of the output shaft to the extrusion mechanism, and the output shaft and the transmission unit. And an elastically deformable connecting member that rotates the transmitting portion.

  According to the medicinal-solution administration device according to the present invention, since it is configured as described above, the influence of the positional deviation between the output shaft of the motor and the rotation shaft of the transmission unit is mitigated using the elasticity of the connecting member. Thereby, the transmission loss in the connection part of the output shaft of a motor and the rotating shaft of a transmission part can be suppressed.

It is the schematic which shows the chemical | medical solution administration apparatus concerning embodiment of this invention. It is a disassembled perspective view which shows the liquid feeding main-body part of a chemical | medical solution administration apparatus. It is a top view which shows the injection part of a chemical | medical solution administration apparatus. 4A and 4B are enlarged cross-sectional views taken along line 4-4 of FIG. 3, in which FIG. 4A shows a state before the cannula is introduced into the living body, and FIG. It is a figure which shows a mode that it introduced. FIG. 4C is a view showing a state where the puncture device is removed and the cannula is left in the living body. FIG. 5 (A) is a schematic plan view showing the structure of each part in the liquid delivery main body part of the drug solution administration device according to the embodiment, and FIG. 5 (B) is an enlarged view of the drive mechanism in FIG. 5 (A). 6A and 6B are cross-sectional views taken along line 6-6 of FIG. 5, in which FIG. 6A shows a state before the injection portion and the liquid supply portion are connected, and FIG. 6B shows the injection portion and the liquid supply portion. It is a figure which shows the state which connected the part. It is the fragmentary sectional view which expands the vicinity of the motor and gear of FIG. 5 (A) and FIG. 5 (B), and shows the connection part of a connection member and a gear in a partial cross section. FIGS. 8A and 8B are a perspective view and a front view showing a first gear constituting the transmission portion and a blocking member provided integrally with the first gear. It is a perspective view which shows the spring member which comprises a connection member. FIG. 8 is a partial cross-sectional view similar to FIG. 7, illustrating a position adjustment between the output shaft of the motor and the rotation shaft of the first gear when the spring member is attached. It is a top view shown about the gear and feed screw which comprise an extrusion mechanism. 12 (A) and 12 (B) are a perspective view and a front view showing a gear constituting the extrusion mechanism. 13 (A) and 13 (B) are a perspective view and a front view showing a feed screw constituting the extrusion mechanism. It is sectional drawing which passes along the approximate center of the output shaft of a motor in the chemical | medical solution administration device which concerns on the modification of this invention, and shows connection with a connection member and a 1st gear. It is a perspective view shown about the spring member concerning the modification of this invention.

  Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings. In addition, the following description does not limit the technical scope and terms used in the claims. In addition, the dimensional ratios in the drawings are exaggerated for convenience of explanation, and may differ from actual ratios.

  Hereinafter, with reference to FIGS. 1-13, the chemical | medical solution administration apparatus 100 which concerns on this embodiment is explained in full detail. 1-6 is a figure where it uses for description of a structure of each part of the chemical | medical solution administration apparatus 100 which concerns on this embodiment. 7 to 10 are diagrams for explaining the drive mechanism 131 and the like of the drug solution administration device 100. FIG. FIG. 11 to FIG. 13B are views for explaining the push-out mechanism 143 and the like of the chemical solution administration device 100.

  The drug solution administration device 100 according to the present embodiment is configured as a portable insulin administration device 100 that delivers insulin as a drug solution into the living body of a diabetic patient who is a user. In the following description, the drug solution administration device 100 is also referred to as an insulin administration device 100.

  As shown in FIG. 1, the insulin administration device 100 performs a liquid feeding main body 10 that performs a liquid feeding operation for feeding insulin, which is a drug solution, into a living body, and gives various operation instructions to the liquid feeding main body 10. A remote controller 20. Hereinafter, the configuration of each part of the insulin administration device 100 will be described in detail.

  As shown in FIG. 2, the liquid feeding main body unit 10 includes a cannula 113 or the like placed in the user's living body, and drives the injection unit 11 attached to the user's living body and members necessary for the liquid feeding operation. A liquid feed reuse unit 13 including a driving mechanism 131 that generates a driving force, a liquid medicine storage unit 141 filled with insulin, and a feed mechanism including an extrusion mechanism 143 used when the liquid medicine filled in the liquid medicine storage unit 141 is delivered. A liquid delivery unit 12 including a liquid disposal unit 14.

  The injection unit 11 and the liquid feeding unit 12 are configured to be connected and separated. The user separates the medicinal solution storage unit 141 filled with insulin and the liquid feeding unit 12 including an electrical mechanism from the injecting unit 11 while the injecting unit 11 is attached to the living body, for example, when taking a bath. By performing this operation, it is possible to prevent the insulin in the drug solution storage unit 141 from being heated and the liquid from adhering to the electrical mechanism in the liquid feeding unit 12 to get wet.

  Moreover, the liquid feeding reuse part 13 and the liquid feeding disposable part 14 are comprised so that connection separation is possible. When the insulin or the like in the drug solution storage unit 141 has been used up after a predetermined period of time, the liquid supply reuse unit 13 and the liquid supply disposable unit 14 are separated, and the liquid supply disposable unit 14 is made disposable (disposable) to be new. Can be exchanged for something. On the other hand, the liquid supply reuse unit 13 is mounted with relatively expensive components such as a motor 136 and a gear group 137, which will be described later, which are less expensive to replace than components mounted on the liquid supply disposable unit 14. In this way, a component member discarded after use for a predetermined period and a relatively expensive component member are mounted in different housings, respectively, and the relatively expensive component member is mounted in the liquid feeding reuse unit 13 and can be reused. By doing so, it is possible to reduce the manufacturing cost of the apparatus and the cost associated with use. Each configuration will be described below.

  First, the injection part 11 will be described. As shown in FIG. 2 and the like, the injection part 11 includes an injection main body part (also referred to as a cradle) 111, a sticking part 112 for attaching the injection main body part 111 to the living body of the user, and protrudes from the injection main body part 111. And a support member 114 that is placed on the injection main body portion 111 and supports the cannula 113.

  As shown in FIG. 2, the injection main body 111 includes a flat plate-like placement portion 111 a and a vertical wall portion 111 b that rises a part of the outer peripheral edge of the placement portion 111 a. As shown in FIGS. 4A and 4B, an insertion hole 111c through which the cannula 113 can be inserted is formed in the mounting portion 111a.

  In addition, as shown in FIG. 2, the vertical wall portion 111b has an engagement portion for maintaining a mechanical connection state with a second housing 145 of a liquid delivery disposable portion 14 to be described later, toward the opposing surface. A protruding projection 111d and a through hole 111e are formed. When the second housing 145 of the liquid delivery disposable part 14 is slid and connected to the injection main body 111, the protrusion 111 d is fitted into a groove 145 c formed on the outer side of the second housing 145. Further, the hooking portion 145d formed in the second housing 145 is hooked in the through hole 111e. Note that the shape of the engaging portion is not limited to the above shape as long as the injection main body portion 111 and the second housing 145 of the liquid delivery disposable portion 14 can be connected and separated.

  As shown in FIG. 3 and FIGS. 4A to 4C, the pasting portion 112 is configured by a substantially rectangular sheet-like member. Adhesiveness of the pasting portion 112 is added to the surface opposite to the surface on which the vertical wall portion 111b rises in the placement portion 111a of the injection main body portion 111. Using the adhesiveness of the sticking part 112, the injection part 11 can be stuck to the living body of the user. In addition, the sticking part 112 may be inadvertently attached to the surface of the sticking part 112 having adhesiveness by using a removable release paper that covers and protects the sticking part 112. May be prevented.

  The cannula 113 is punctured into the living body and used to introduce a medical solution such as insulin from the medical solution storage unit 141 into the living body. As shown in FIG. 4A, the cannula 113 has a cylindrical portion and a truncated cone-shaped portion that is formed continuously with the cylindrical portion, and the cylindrical portion and the truncated cone-shaped portion. Have a continuous lumen through which insulin circulates. The cannula 113 is configured to have a so-called funnel-like shape by having the above-described shape.

  As shown in FIG. 4, the support member 114 includes a base 114 a that supports the cannula 113, a connection port 114 b that includes a lumen into which the liquid feeding pipe 142 (see FIG. 6) of the liquid feeding disposable part 14 is inserted, A cap 114c attached so as to cover the connection port 114b; a lid member 114d attached to the upper surface of the base 114a (the surface opposite to the mounting surface on the injection main body 111); the base 114a and the lid member 114d; And a seal member 114e provided between the two.

  The base 114a is a part that becomes a base of the support member 114, and is configured in a substantially cylindrical shape in the present embodiment. As shown in FIG. 4C and the like, the base 114a includes an internal space 114f in which the cannula 113 is installed. The internal space 114f has a funnel shape in accordance with the shape of the cannula 113 so that the cannula 113 can be supported. It is configured as follows.

  As shown in FIG. 4A and the like, the connection port 114b extends in a direction intersecting the cylindrical axis of the cannula 113 at the base 114a. The lumen of the connection port 114b communicates with the internal space 114f of the base 114a.

  The cap 114c is formed of a material that can insert a liquid feeding pipe 142 of the liquid feeding disposable section 14 to be described later, and can keep liquid tight between the liquid feeding pipe 142 and the connection port 114b. The material is preferably rubber.

  As shown in FIG. 4C, the lid member 114d has a function of pressing the seal member 114e. A through hole into which a needle N of a puncture tool M, which will be described later, can be inserted is formed in the lid member 114d coaxially with the axial direction of the cannula 113.

  The seal member 114e is configured so that the needle N of the puncture device M can be inserted, and prevents insulin from leaking out from the through hole of the lid member 114d after the puncture device M is removed. Examples of the material of the seal member 114e include rubber. The puncture tool M shown in FIGS. 4A and 4B is a schematic diagram in which a detailed configuration is omitted.

  The indwelling of the cannula 113 in the living body is supported, for example, in the direction in which the needle N and the cannula 113 protrude from the placement portion 111a, and the needle N that can be inserted into the lumen of the cannula 113 supported by the support member 114. It can be performed by a puncture device M including a biasing member (not shown) that applies a biasing force to the member 114 and the needle N.

  Specifically, first, the user attaches the injection main body 111 to the body surface of the user using the attaching portion 112. Next, the needle N is inserted from the through hole formed in the lid member 114 d of the support member 114, and the support member 114 is attached to the puncture tool M so that the needle N passes through the lumen of the cannula 113. Next, as shown in FIG. 4A, the puncture tool M is attached on the placement portion 111a. Next, as shown in FIG. 4B, the support member 114 and the needle N are moved toward the direction in which the needle N and the cannula 113 protrude from the placement portion 111a by the urging force of the urging member included in the puncture tool M. Eject. Next, as shown in FIG. 4C, the puncture tool M including the needle N is removed from the placement portion 111a with the support member 114 attached to the placement portion 111a. As a result, the cannula 113 is placed in the living body.

  Next, the liquid feeding reuse unit 13 will be described. As shown in FIG. 2 and FIG. 5 (A), the liquid feed reuse unit 13 determines the amount of liquid fed by the drive mechanism 131 that drives the members necessary for performing the liquid feed operation, and the liquid feed operation. A liquid feed amount detection unit 132 (corresponding to a detection unit) to be detected, a first communication unit 133 that communicates with the remote controller 20, a first control unit 134 that controls the drive mechanism 131, the first communication unit 133, and the like, and these And a first housing 135 that holds the first housing 135. In FIG. 5A, the part surrounded by a dotted line X represents a part attached to the liquid feeding reuse part 13, and the part surrounded by a one-dot chain line Y represents a part attached to the liquid feeding disposable part 14. . Further, in FIG. 5A, the first housing 135 is omitted for easy understanding.

  As shown in FIGS. 5 (A), 5 (B) and 7, the drive mechanism 131 includes a motor 136 having an output shaft 136 a that causes rotation by the electric power from the battery 144 of the liquid delivery disposable unit 14, and the motor 136. The gear group 137 that decelerates the rotation generated by the transmission mechanism and transmits it to the push-out mechanism 143 of the liquid delivery disposable section 14, and the output shaft 136a of the motor 136 and the first gear 137a (corresponding to the transmission section) constituting the gear group 137. And a connecting member 138 to be connected.

  The motor 136 generates a driving force necessary for moving the slide portion 146 of the push-out mechanism 143 on the output shaft 136a as a rotational motion. The motor 136 uses a stepping motor in this embodiment. The stepping motor is preferable from the viewpoint of safety because the rotation of the motor is stopped at the time of a short circuit. However, the specific mode of the motor 136 is not limited to this as long as it can generate a driving force by rotation and can be mounted on the portable insulin administration device 100. The motor 136 may be, for example, a DC motor, an AC motor, or the like other than the stepping motor.

  The gear group 137 is used to transmit the rotational power generated from the motor 136 to the extrusion mechanism 143 that presses the chemical solution storage unit 141. In this embodiment, as shown in FIG. 5B, the gear group 137 includes a first gear 137a connected to the motor 136, a second gear 137b that meshes with an adjacent gear, a third gear 137c, and a fourth gear. 137d.

  The first gear 137a includes one type of tooth that meshes with an adjacent gear. In contrast, the second gear 137b, the third gear 137c, and the fourth gear 137d are provided with two types of teeth that mesh with adjacent gears in the axial direction in which the gear rotates.

  The second gear 137b is disposed adjacent to the first gear 137a and the third gear 137c in the direction intersecting the rotation axis of the first gear 137a (the vertical direction in FIGS. 5A and 5B). The second gear 137b includes teeth 137e that mesh with the teeth of the first gear 137a and teeth 137f that mesh with the teeth 137g of the third gear 137c. The tooth 137e has a larger diameter than the tooth 137f.

  The third gear 137c is disposed adjacent to the second gear 137b and the fourth gear 137d in the direction intersecting the rotation axis of the first gear 137a (the vertical direction in FIGS. 5A and 5B). The third gear 137c includes teeth 137g that mesh with the teeth 137f of the second gear 137b and teeth 137h that mesh with the teeth 137i of the fourth gear 137d. The tooth 137g has a diameter larger than that of the tooth 137h.

  The fourth gear 137d is disposed adjacent to the third gear 137c and the fifth gear 148 of the liquid delivery disposable unit 14 in the direction intersecting the rotation axis of the first gear 137a (the vertical direction in FIG. 5). The fourth gear 137d includes a tooth 137i that meshes with the tooth 137h of the third gear, a tooth 137j that meshes with a tooth 148a (see FIG. 12) of the fifth gear 148 that constitutes the push-out mechanism 143 of the liquid delivery disposable unit 14 described later, Have The tooth 137i has a diameter larger than that of the tooth 137j.

  The gear group 137 and the fifth gear 148 are constituted by spur gears. However, the present invention is not limited to this as long as the power from the rotation from the motor 136 can be transmitted to the extrusion mechanism 143. Further, as long as the gear group 137 and the fifth gear 148 can decelerate and transmit the torque from the motor 136 to a set value, the gear configuration such as the number of gears, the number of teeth, and the type of teeth is not limited to the above. In the present embodiment, the rotation direction of the input gear corresponding to the first gear 137a and the rotation direction of the output gear corresponding to the fifth gear 148 may be the same or different. The materials of the gear group 137 and the fifth gear 148 are not particularly limited as long as the output from the output shaft 136a of the motor 136 can be transmitted to the extrusion mechanism 143, and examples thereof include resin materials such as metal and plastic.

  Next, the connecting member 138 will be described with reference to FIGS. As shown in FIGS. 7 and 9, the connecting member 138 includes an elastically deformable spring member 138 a and an attachment member 138 f that rotates together with the output shaft 136 a of the motor 136 and is attached to the output shaft 136 a.

  The spring member 138a relieves transmission loss that may be caused by a displacement between the output shaft 136a of the motor 136 and the rotation shaft of the first gear 137a due to the elasticity of the member itself. As shown in FIG. 9, the spring member 138a includes an end 138b connected to the output shaft 136a, an other end 138c connected to the first gear 137a, and an end 138b and the other end 138c. An elastically deformable deforming portion 138d extending in a spiral shape.

  As shown in FIG. 9 in the present embodiment, the spring member 138a is configured by a spring (coil spring) that is wound in a coil shape (spiral shape). Therefore, the deforming portion 138d is configured in a spiral shape, and the one end portion 138b and the other end portion 138c are configured as a helical end portion. Further, since the deformed portion 138d is formed in a spiral shape, a space portion 138e partitioned from the outside is formed on the inner side in the radial direction (radial direction) than the spiral shape as shown in FIG. .

  An attachment member 138f is attached to the output shaft 136a of the motor 136. Further, the inside of the spiral shape on the one end 138b side of the spring member 138a abuts on the outer surface of the attachment member 138f, and the spring member 138a is attached to the attachment member 138f. As described above, the motor 136 and the spring member 138a are connected to each other through the spring member 138a and the attachment member 138f.

  On the other hand, a support portion 137k formed in a convex shape is provided at the central portion of the first gear 137a in the radial direction on the motor side, as shown in FIGS. The support portion 137k is inserted into the space portion 138e of the spring member 138a, and is attached so that the spring member 138a is fitted to the support portion 137k, thereby connecting the spring member 138a and the first gear 137a. The spring member 138a expands the spiral shape of the spring member 138a and, as an example, attaches one end 138b to the attachment member 138f and supports the other end 138c while twisted in the direction r2 opposite to the spiral winding direction r1. Attach to part 137k. As described above, the motor 136 and the first gear 137a are connected via the connecting member 138, thereby preventing slippage at the connecting portion of the mounting member 138f and the spring member 138a. Slip at the connecting portion of the 1 gear 137a is prevented. Therefore, the rotation of the output shaft 136a of the motor 136 is favorably transmitted to the first gear 137a via the connecting member 138 including the spring member 138a.

  As shown in FIG. 7, the mounting member 138f has a hollow hole (not shown) for mounting the output shaft 136a of the motor 136 and a substantially cylindrical outer surface for mounting a helical shape on the one end 138b side of the spring member 138a. Have. The attachment member 138f is configured to include a cylindrical portion in appearance and a frustoconical portion formed continuously in a cylindrical shape in the axial direction of the cylindrical shape. However, if the output shaft 136a of the motor 136 and the spring member 138a are attached and the rotation of the output shaft 136a of the motor 136 can be transmitted to the first gear 137a, the shape is not limited to the above.

  Here, the position adjustment of the output shaft 136a of the motor 136 and the rotation shaft of the first gear 137a when the spring member 138a is attached will be described below.

  Here, as shown in FIG. 10, when the spring member 138a is attached to the output shaft 136a of the motor 136, the positions of the rotation shafts of the output shaft 136a and the first gear 137a are substantially in the radial direction of the helical shape of the spring member 138a. Consider the case where they are separated from each other. In this case, the spring member 138a is deformed so that the length of the spiral shape of the spring member 138a in the substantially radial direction is partially enlarged and the number of turns of the spiral shape is reduced. In this case, a restoring force acts on the spring member 138a, and the spring member 138a tries to return to a state where no external force acts.

  That is, the length of the spiral shape of the spring member 138a in the substantially radial direction is reduced, and the spiral member is deformed so that the number of turns of the spiral shape is restored (increased). This prevents the output shaft 136a of the motor 136 and the rotating shaft of the first gear 137a from approaching each other when the spring member 138a is attached, so that the positions of the two are extremely separated.

  Return to the description of the configuration. As shown in FIG. 7, the liquid feeding amount detection unit 132 includes a blocking member 132 a provided on the motor 136 side of the first gear 137 a and a light emitting unit 132 b disposed so as to face each other with the blocking member 132 a interposed therebetween. And an optical sensor including the light receiving portion 132c.

  As shown in FIGS. 8A and 8B, the blocking member 132a is provided with a plurality of substantially fan-shaped shapes such as fan blades at regular angular intervals in the circumferential direction of the first gear 137a. As shown in FIG. 7, when the detection light S emitted from the light emitting unit 132b of the optical sensor passes through a portion of the blocking member 132a where the blade shape is not provided, the light receiving unit 132c receives the detection light S. Conversely, when the detection light S from the light emitting unit 132b is blocked by the blade shape of the blocking member 132a, the light receiving unit 132c does not receive the detection light S. Since the blade shape of the blocking member 132a is provided at regular intervals, the rotation speed of the output shaft 136a of the motor 136 is detected based on the time interval (frequency) at which the detection light S is received. Since the reduction ratio by the gear group 137 and the fifth gear 148 and the screw pitch of the feed screw 147 of the extrusion mechanism 140 are fixed (not variable), the chemical solution is detected by detecting the rotation speed of the output shaft 136a of the motor 136. Can be detected.

  The blocking member 132a is configured by providing three fan-shaped blade shapes in FIG. 8A or the like. However, if the blocking and passing of the detection light S can be switched, the blade shape and the number of the blade shapes are the same. Etc. are not limited to FIGS. 8 (A) and 8 (B). Further, in the present embodiment, the liquid feeding amount is detected by detecting the rotation speed of the output shaft 136a of the motor 136 by the liquid feeding amount detection unit 132, but the method for detecting the liquid feeding amount is not limited to this. For example, it is also possible to obtain the liquid feeding amount from a control signal sent to the motor 136. Moreover, although the optical sensor is used for the detection of rotation speed, if the rotation amount of a motor can be detected, it will not be limited to an optical sensor.

  As shown in FIG. 5A, the first communication unit 133 includes electronic devices necessary for communication with the remote controller 20. As will be described later, the remote controller 20 is provided with a second communication unit 202, which communicates information with the first communication unit 133 of the liquid-feed reuse unit 13 using BLE (Bluetooth Low Energy) communication which is short-range wireless communication. It is configured to be able to send and receive.

  The first control unit 134 controls operations of the motor 136, the first communication unit 133, the liquid feeding amount detection unit 132, and the like that configure the drive mechanism 131. The first control unit 134 is configured by a known microcomputer including a CPU, RAM, ROM, and the like.

  As shown in FIG. 2, the first housing 135 includes an upper surface 135 a that covers the configuration of the drive mechanism 131, the liquid feeding amount detection unit 132, the first communication unit 133, the first control unit 134, and the outer peripheral edge of the upper surface 135 a. And a side wall 135b partially raised. A drive mechanism 131, a liquid feeding amount detection unit 132, a first communication unit 133, and a first control unit 134 are operatively attached to the upper surface 135a.

  Moreover, the 1st housing 135 has a convex part (not shown) which protrudes inward from the inner surface of the side wall 135b as a structure which can connect and separate the liquid feeding reuse part 13 with the liquid feeding disposable part 14. As shown in FIG. In the present embodiment, the first housing 135 is made of resin parts such as plastic, but is not limited to this as long as it has a certain degree of strength.

  Next, the liquid delivery disposable part 14 will be described. As shown in FIG. 5 (A), the liquid delivery disposable part 14 is a liquid delivery pipe that communicates the drug solution storage part 141 filled with insulin with the lumen of the connection port 112b provided in the injection part 11 and the drug solution storage part 141. 142, an extruding mechanism 143 that is mechanically connected to the driving mechanism 131 and pushes the insulin in the drug solution storage unit 141 to the liquid feeding tube 142, a battery 144 that supplies electric power to the driving mechanism 131 and the like, and a first holding the same. 2 housings 145.

  The chemical solution storage unit 141 has a cylindrical shape. A liquid feeding pipe 142 is connected to one end of the chemical liquid storage unit 141. An opening 141 a is formed at the other end of the chemical solution storage unit 141. A slide part 146 of an extrusion mechanism 143, which will be described later, is inserted into the drug solution storage part 141 from the opening 141a, and insulin is stored in a space partitioned by the drug solution storage part 141 and the slide part 146.

  As shown in FIGS. 6A and 6B, in the present embodiment, the liquid feeding tube 142 is constituted by a metal thin tube having a sharp tip shape. As shown in FIG. 6 (A), when the liquid feeding section 12 is connected to the injection section 11 while being slid, the sharp tip of the liquid feeding pipe 142 is connected to the injection section 11 as shown in FIG. 6 (B). It penetrates the cap 114c and is inserted into the lumen of the connection port 114b.

  As shown in FIG. 5 (A), the push-out mechanism 143 meshes with the slide part 146 that can move forward and backward in the internal space of the chemical solution storage part 141 and the female screw part 146d formed on the slide part 146, thereby causing the slide part 146 to move. A feed screw 147 that moves forward and backward, and a fifth gear 148 that meshes with the fourth gear 137 d of the drive mechanism 131 and is connected to the feed screw 147 are provided.

  As shown in FIG. 5A, the slide portion 146 includes an extruding member 146a capable of moving back and forth in the chemical solution storage portion 141 while maintaining a sealing property so that the chemical solution does not leak to the slide portion 146 side, and a feed screw 147. A feed plate 146b formed with an internal thread portion 146d that meshes with the connecting member 146c, and a connecting plate 146c that connects the push member 146a and the feed plate 146b.

  The pushing member 146a is inserted from the opening 141a of the chemical solution storage unit 141 in order to form a space for storing the chemical solution in the internal space of the chemical solution storage unit 141. The push member 146a is fitted to the cylindrical inner wall surface so that the chemical liquid does not leak from the boundary between the push member 146a and the cylindrical inner wall surface of the chemical solution storage portion 141, while the inner wall surface is fitted in FIG. Move forward and backward in the left-right direction. The size (volume) of the storage space (the internal space of the chemical solution storage unit 141) that stores the chemical solution varies depending on the position of the pushing member 146a in the chemical solution storage unit 141. The pushing member 146a is sometimes called a pusher or a pusher.

  The feed plate 146b is configured by forming a hole in the plate shape and forming a female screw portion 146d that meshes with the male screw portion 147a of the feed screw 147 in the hole.

  The connecting plate 146c connects the push member 146a and the feed plate 146b using two plates. However, the shape of the connection plate 146c is not limited to this as long as the push member 146a and the feed plate 146b can be connected and operated together. In addition to the above, the connecting plate 146c may be configured in a hollow shape that fits around the cylindrical inner wall surface of the chemical solution storage unit 141, for example.

  As shown in FIGS. 13A and 13B, the feed screw 147 has a male screw portion 147a that meshes with the female screw portion 146d of the feed plate 146b, and a screw head having a concave groove portion that meshes with the bit 148c of the fifth gear 148. Part 147b. As the feed screw 147, as shown in FIGS. 11 and 13 (A) and 13 (B), a general screw head or a screw having a male screw shape standardized by JIS or ISO, a so-called general-purpose product is used. ing. The feed screw 147 is operably held in the second housing 145 of the liquid delivery disposable section 14, and the cost reduction as the insulin administration device 100 can be reduced by using a general-purpose product standardized by ISO or the like as described above. I am trying.

  The screw head 147b is provided with a concave groove for transmitting the driving force generated by the rotation of the fifth gear 148. Part of the male screw portion 147a is engaged with the female screw portion 146d of the feed plate 146b, and rotation from the fifth gear 148 is transmitted to the screw head portion 147b, thereby causing rotational movement from the motor 136 and the gear group 137. Convert to linear motion.

  Examples of the material of the feed screw 147 include, but are not limited to, rolled steel and carbon steel. Further, as the feed screw 147, a so-called right screw in which the spiral winding direction of the male screw portion 147a is clockwise may be used, or a left screw that is counterclockwise may be used.

  The fifth gear 148 is disposed in the second housing 145 at a position that meshes with the fourth gear 137d in a state where the liquid feeding reuse portion 13 and the liquid feeding disposable portion 14 are connected.

  As shown in FIGS. 12A and 12B, the fifth gear 148 includes teeth 148a of the fifth gear 148, a rotation shaft 148b serving as the rotation center of the fifth gear 148, and a feed screw 147 of the rotation shaft 148b. And a bit 148c that engages with (engages with) the concave groove of the screw head 147b of the feed screw 147, which is provided at the end on the side.

  The bit 148c is configured in the same manner as the tip shape of a driver (also called a screw driver, screwdriver, etc.) that tightens a general screw. By configuring the bit 148c as described above, the bit 148c meshes with the concave groove of the screw head 147b of the feed screw 147, and transmits the power generated by the rotation of the fifth gear 148.

  In this embodiment, the concave groove portion of the screw head 147b and the bit 148c are formed in a cross shape. However, a general-purpose screw can be used for the feed screw 147, and the shape is not limited to the cross shape as long as the slide portion 146 can be moved forward and backward using the rotation of the fifth gear 148. Further, since the tooth 148a and the rotating shaft 148b have the same shape as a known shape, the description thereof is omitted.

  In addition, the second gear 137b, the third gear 137c, the fourth gear 137d, and the fifth gear 148 shown in FIG. 5B in this specification are mechanically connected to the first gear 137a, and are output from the motor 136. This corresponds to a plurality of gears that rotate in conjunction with the rotation of the shaft 136a. Further, the feed screw 147 and the slide portion 146 shown in FIG. 5 (A) have the rotation transmitted through the second gear 137b, the third gear 137c, the fourth gear 137d, and the fifth gear 148 of the push-out mechanism 143. Corresponds to a conversion mechanism that converts forward and backward movement.

  The feed screw 147 and the fifth gear 148 are rotatably attached to the second housing 145.

  When the fifth gear 148 rotates with the rotation of the fourth gear 137d constituting the drive mechanism 131, the feed screw 147 rotates. As the feed screw 147 rotates, the feed plate 146b moves along the helical axis of the male thread portion 147a of the feed screw 147. The pushing member 146a connected to the feed plate 146b via the connecting plate 146c moves in the chemical solution storage unit 141 as the feed plate 146b moves. When the extruding member 146a moves in the direction in which the extruding member 146a is pushed into the medicinal solution storage unit 141 (the direction in which the volume of the accommodating space decreases), insulin in the accommodating space formed by the medicinal solution storing unit 141 and the extruding member 146a enters the liquid feeding tube 142. The liquid is sent.

  When the battery 144 is connected to the liquid feeding reuse unit 13 and the liquid feeding disposable unit 14, the motor 136, the liquid feeding amount detection unit 132, the first communication unit 133, and the first control unit 134 in the liquid feeding reuse unit 13 are connected. Are electrically connected to each other to supply power. In the present embodiment, the battery 144 is configured by connecting two batteries in series. However, the number of batteries and the connection method such as series or parallel are not particularly limited as long as power can be supplied to each unit.

  As shown in FIG. 2, the second housing 145 has a bottom surface 145 a on which components such as a chemical solution storage unit 141, a liquid feeding pipe 142, an extrusion mechanism 143, and a battery 144 are placed, and an outer peripheral edge portion of the bottom surface 145 a. And a side wall 145b.

  The second housing 145 is configured to be connected to and separated from the injection main body 111. Specifically, in the present embodiment, the side wall 145b has a groove 145c that can be fitted to the protrusion 111d formed on the injection main body 111 and a through hole formed in the injection main body 111 as shown in FIG. A hooking portion 145d that hooks on 111e is formed. When the second housing 145 is slid to the injection main body 111, the projection 111 d of the injection main body 111 and the groove 145 c of the second housing 145 are fitted, and the through hole 111 e of the injection main body 111 is inserted into the through hole 111 e of the second housing 145. The hooking portion 145d is hooked. As a result, the second housing 145 is connected to the injection main body 111.

  The second housing 145 has a concave portion (not shown) that meshes with a convex portion provided on the side wall 135 b of the first housing 135, so that the second housing 145 can be connected to and separated from the first housing 135. By connecting the first housing 135 and the second housing 145, the drive mechanism 131 mounted on the first housing 135 and the push-out mechanism 143 mounted on the second housing 145 are mechanically connected. In addition, the motor 136, the liquid supply amount detection unit 132, the first communication unit 133, and the first control unit 134 mounted on the first housing 135 are electrically connected to the battery 144 mounted on the second housing 145. .

  In the present embodiment, the second housing 145 is made of resin parts such as plastic, but the material is not limited to this as long as the first housing 135 has a certain degree of strength.

  Next, the remote controller 20 will be described. As shown in FIG. 1, the remote controller 20 includes a remote controller body 201, a second communication unit 202 that can wirelessly communicate with the first communication unit 133, and a second control unit 203 that controls the insulin administration device 100 in an integrated manner. The remote control main body 201 has a monitor 204, a button 205 that can accept instructions from the user, and a battery 206 that supplies power to each part of the remote control 20.

  The remote control main body 201 is configured to have a size that can be held by a user with one hand, and is configured by a relatively lightweight resin component such as plastic.

  The second communication unit 202 includes an electronic device necessary for communication with the first communication unit 133 of the liquid feeding main body unit 10. The second communication unit 202 uses the BLE (Bluetooth Low Energy) communication, which is a short-range wireless communication technology capable of performing communication with low power in the present embodiment, to exchange information with the liquid feeding main body unit 10. It is configured to transmit and receive. However, the communication method is not limited to BLE as long as wireless communication can be performed with the liquid feeding main body unit 10.

  The second control unit 203 is configured by a known microcomputer including a CPU, RAM, ROM, and the like. The CPU reads out and executes various programs stored in advance in the ROM, thereby controlling the liquid feeding operation. Note that the monitor 204, the button 205, and the battery 206 have the same configuration as that of a known one, and thus the description thereof is omitted.

  Next, a usage example of the insulin administration device 100 will be described.

  First, prior to the use of the insulin administration device 100, the user attaches the injection unit 11 to the living body, and performs the treatment of placing the cannula 113 in the living body using the puncture tool M as described above.

  In addition, prior to the use of the insulin administration device 100, the user connects and integrates the liquid feeding reuse unit 13 and the liquid feeding disposable unit 14 to form the liquid feeding unit 12. Then, the user operates the remote controller 20 to give an instruction for priming (first priming) for filling the liquid feeding tube 142 of the liquid feeding disposable part 14 with insulin. In response to the instruction from the remote controller 20, the first control unit 134 operates the drive mechanism 131 to move the slide unit 146 of the extrusion mechanism 143 by a predetermined amount, so that the insulin stored in the drug solution storage unit 141 is stored. The liquid is fed to the liquid feeding pipe 142, and the liquid feeding pipe 142 is filled with insulin.

  Next, the liquid feeding part 12 is connected to the injection part 11.

  Next, the user operates the remote controller 20 to instruct priming (second priming) so that the lumen of the cannula 113 is filled with insulin.

  Next, the user operates the remote controller 20 to perform a basal mode in which insulin is delivered over time at a constant amount, a bolus mode in which the amount of insulin delivered per unit time is temporarily increased, and the like. The liquid feeding mode is appropriately selected to deliver insulin into the living body.

  Next, the effect of this embodiment is demonstrated. The insulin administration device 100 according to the present embodiment connects the output shaft 136a of the motor 136 and the first gear 137a, thereby connecting the output shaft 136a to the elastically deformable connecting member that rotates the first gear 137a. 138. Therefore, the influence of the positional deviation between the output shaft 136a of the motor 136 and the rotation shaft of the first gear 137a can be mitigated using the elasticity of the connecting member 138. Therefore, it is possible to suppress transmission loss caused by positional deviation between the output shaft 136a and the rotation shaft of the first gear 137a, and perform an operation of administering a chemical solution when the output is relatively small as in the motor 136 of the present embodiment. It can be done well.

  The connecting member 138 spirally extends between one end 138b connected to the output shaft 136a, the other end 138c connected to the first gear 137a, and the one end 138b and the other end 138c. And a spring member 138a including a deformable portion 138d that is elastically deformable. Therefore, the connection between the motor 136 and the first gear 137a can be ensured by the above configuration.

  The first gear 137a is configured to have a support portion 137k that is inserted into a space portion 138e defined inside the deformable portion 138d of the spring member 138a and supports the spring member 138a. Thereby, the spring member 138a and the 1st gear 137a can be connected favorably.

  In addition, the liquid feeding amount detection unit 132 is provided integrally with the light emitting unit 132b that emits the detection light S, the light receiving unit 132c that receives the detection light S, and the first gear 137a, and rotates with the rotation of the first gear 137a. And a blocking member 132a that switches between blocking and passing the detection light S between the light emitting unit 132b and the light receiving unit 132c. By configuring the liquid feeding amount detection unit 132 as described above, the time interval of the signal that changes in accordance with the rotation of the output shaft 136a of the motor 136 is detected, and thereby the number of rotations of the output shaft 136a of the motor 136 is detected. can do.

  By disposing the spring member 138a between the output shaft 136a of the motor 136 and the first gear 137a, the spring member 138a absorbs vibration from the output shaft 136a, and the blocking member 132a vibrates from the output shaft 136a. Resonance can be suppressed. Thereby, it can suppress that the detection accuracy of the rotation speed of the output shaft 136a of the motor 136 falls.

  In addition, a stepping motor can be used as the motor 136 constituting the drive mechanism 131 as an example. Although the stepping motor operates intermittently, by providing the connecting member 138 between the output shaft 136a of the motor 136 and the first gear 137a as described above, intermittent vibration from the stepping motor is caused by the first gear 137a. Can be suppressed. Therefore, it can contribute to noise reduction.

  In the present embodiment, the drive mechanism 131 includes a second gear 137b, a third gear 137c, and a fourth gear 137d that rotate in conjunction with the rotation of the first gear 137a, and the push-out mechanism 143 includes a fifth gear 148. Thus, the slide portion 146 and the feed screw 147 of the push-out mechanism 143 are configured to convert the rotation from the plurality of gears into forward and backward movements. Therefore, the pushing member 146a can be linearly moved forward and backward by the above-described configuration, so that a drug solution such as insulin can be delivered from the cannula 113.

  The second housing 145 constituting the liquid delivery disposable unit 14 holds the chemical solution storage unit 141 and the extrusion mechanism 143 in an operable manner, and the first housing 135 constituting the liquid delivery reuse unit 13 has a drive mechanism 131. It is configured to be held operatively. That is, among the members constituting the insulin administration device 100, a member with a high replacement frequency is attached to the liquid delivery disposable part 14, and a member with a low replacement frequency is attached to the liquid delivery reuse part 13 as a position to be reused. . Therefore, a member with a high replacement frequency can be easily replaced, which can contribute to a reduction in running cost and the like.

(Modification)
14 and 15 are diagrams for explaining the connecting member 138 and the like of the insulin administration device 100 according to the modification of the present invention. In the following modified examples, description of the same configuration as that of the above-described embodiment is omitted.

  In the above, an embodiment is described in which the connecting member 138 is connected to the first gear 137a by attaching the spring member 138a constituting the connecting member 138 to the convex support portion 137k of the first gear 137a at the other end 138c. However, it is not limited to this.

  In addition to the above, as shown in FIGS. 14 and 15, the spring member 138 h constituting the connecting member 138 g is a hook-shaped hook portion that is hooked and attached to the first gear 137 m on the spiral end portion on the first gear 137 m side. 138j (corresponding to a connection portion) may be provided. In this case, the first gear 137m is provided with an insertion hole 137n (corresponding to a holding portion) through which the hook shape of the hooking portion 138j of the spring member 138h is inserted and attached by hooking the hooking portion 138j.

  With the configuration described above, when the first gear 137m and the output shaft 136a of the motor 136 are displaced, the hooking portion 138j is caught in the insertion hole 137n, so that the rotation from the output shaft 136a is improved. Can be transmitted to the first gear 137a.

  The present invention is not limited to the above-described embodiment, and various modifications can be made within the scope of the claims.

  Although it has been described that the connecting member 138 includes the spring member 138a as a configuration for reducing transmission loss caused by the positional deviation between the output shaft 136a of the motor 136 and the rotation shaft of the first gear 137a, the present invention is not limited thereto. In addition to the above, it is sufficient if the energy caused by the positional deviation can be reduced when the positional deviation occurs between the output shaft 136a of the motor 136 and the rotating shaft of the first gear 137a. For example, in the tube shape made of rubber or the like. You may connect both.

  Further, the blocking member 132a constituting the liquid feeding amount detection unit 132 is provided in the first gear 137a, that is, the first gear 137a and the blocking member 132a are configured as one component. However, the present invention is not limited to this. Not. In addition to the above, it is only necessary that the blocking member 132a rotates integrally with the first gear 137a to detect the rotational speed of the output shaft 136a, and the blocking member 132a and the first gear 137a may be configured as separate parts.

  Further, although the embodiment has been described in which the rotation of the motor 136 from the output shaft 136a is converted into the linear motion by the gear group 137, the fifth gear 148, and the feed screw 147, the present invention is not limited to this. The output shaft 136a and the first gear 137a may be connected by the connecting member 138. In addition to the above, for example, the rotation of the output shaft 136a of the motor 136 may be converted into a linear motion by a rack and pinion.

  Moreover, although the 5th gear 148 which comprises the extrusion mechanism 143 demonstrated the embodiment operatively hold | maintained in the 2nd housing 145 which comprises the liquid feeding disposable part 14, it is not limited to this. The fifth gear 148 may be operatively held in the first housing 135 that constitutes the liquid-feeding reuse unit 13 in the same way as the gear group 137, as long as a frequently exchanged member can be easily replaced.

10 Liquid feeding body,
11 injection part,
12 Liquid feeding part,
13 Liquid Reuse Department,
14 Liquid delivery disposable part,
100 insulin administration device (medical solution administration device),
131 drive mechanism,
132 liquid supply amount detection unit (detection unit),
132a blocking member,
132b light emitting unit,
132c light receiving part,
135 first housing,
136 motor,
136a output shaft,
137 gear group,
137a, 137m first gear (transmission part),
137b second gear (multiple gears),
137c third gear (multiple gears),
137d 4th gear (plural gears),
137k support,
137n insertion hole (holding part),
138, 138g connecting member,
138a, 138h spring member,
138b one end,
138c the other end,
138d deformation part,
138e space part,
138f mounting member,
138j hooking part (connection part),
141 chemical storage part,
143 extrusion mechanism,
145 second housing,
146 slide part (conversion mechanism),
147 feed screw (conversion mechanism),
148 Fifth gear (multiple gears).

Claims (8)

An injection part for injecting a chemical into a living body;
A chemical solution storage unit that communicates with the injection unit and stores the chemical solution to be sent to the injection unit;
An extruding mechanism for moving forward and backward in the chemical liquid storage section and sending the chemical liquid in the chemical liquid storage section to the injection section in accordance with the forward and backward movement;
A driving mechanism for generating a driving force for moving the pushing mechanism forward and backward, and
The drive mechanism is
A motor with a rotating output shaft;
A transmission unit for transmitting rotation of the output shaft to the extrusion mechanism;
A drug solution administration device comprising: an elastically deformable connecting member that rotates the transmission unit in conjunction with rotation of the output shaft by connecting the output shaft and the transmission unit.   The connecting member is elastically deformable extending in a spiral shape between the one end connected to the output shaft, the other end connected to the transmission unit, and the one end and the other end. The medicinal-solution administration device according to claim 1, wherein the medicinal-solution administration device includes a deformable portion.   The medicinal-solution administration device according to claim 2, wherein the transmission unit includes a support unit that is inserted into a space section inside the deformation unit and supports the connection member. The spring member has a connection portion that is formed at the other end portion and extends in a direction intersecting the extending direction of the deformation portion,
The drug solution administration device according to claim 2, wherein the transmission unit includes a holding unit that hooks and holds the connection unit. A detector that detects the rotational speed of the output shaft;
The detector is
A light emitting section for emitting detection light;
A light receiving portion for receiving the detection light;
5. A blocking member that is provided integrally with the transmission unit and switches between blocking and passing the detection light between the light emitting unit and the light receiving unit as the transmission unit rotates. The chemical | medical solution administration apparatus of any one.   The drug solution administration device according to claim 1, wherein the motor is a stepping motor.   A plurality of gears that are mechanically connected to the transmission unit and rotate in conjunction with rotation of the output shaft; and a conversion mechanism that converts the rotation transmitted through the plurality of gears into a forward and backward movement of the push-out mechanism; The medicinal-solution administration device according to any one of claims 1 to 6. A first housing for holding the chemical storage section and the push-out mechanism;
The medicinal-solution administration device according to any one of claims 1 to 7, further comprising: a second housing that holds the drive mechanism and can be connected to and separated from the first housing.